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Dissertations / Theses on the topic 'Phytochemicals compounds'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Mngeni, Nasipi Zamanala. "Bioactive compounds from selected medicinal plants used in antidiabetic treatment." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2665.

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Thesis (MTech (Chemistry))--Cape Peninsula University of Technology, 2017.<br>The continued use and popularity of plant-based traditional medicine demands scientific validation of the therapeutic potential of the medicinal plants used in disease management and treatment. These medicinal plants are to be evaluated for phytochemical constituents and pharmacologically screened for their bioactivity and include the isolation and identification of their bioactive compounds. The diabetes tea and its eight individual plants constituents were collected from Sing Fefur Herbs in McGregor, Western Cape.

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2

Knox, Natalie. "An exploration of ecological concepts in the context of antimicrobial resistance and the use of phytochemical compounds within the ruminant gut microbiome." Agricultural Institute of Canada, publisher of Canadian Journal of Plant Science, 2008. http://hdl.handle.net/1993/14405.

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Secondary plant metabolites have recently been gaining interest in livestock production systems following the ban of in-feed antibiotics within the European Union. The rise in antimicrobial resistance found in pathogenic and non-pathogenic bacteria has lead to increased interest in the research community regarding the use of phythochemicals as an alternative to antibiotics. The purpose of this research was to evaluate the impact of including phytochemicals in a livestock production system. Specifically, a high tannin-containing forage, sainfoin (Onobrychis viciifolia), was evaluated in vitro f

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3

Fujioka, Kazutoshi. "Formation/inhibition and toxicity of reactive carbonyl compounds from oxidized dietary oils : antioxidant properties of phytochemicals measured by headspace solid-phase microextraction/gas chromatography /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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4

Reynertson, Kurt Allerslev. "Phytochemical analysis of bioactive constituents from edible Myrtaceae fruits /." View online, 2007. http://home.earthlink.net/~myrtaceae/Reynertson_dissertation.pdf.

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Thesis (Ph. D.)--City University of New York, 2007.<br>Includes bibliographical references (leaves 100-120) and index. Also available for educational and research purposes in PDF format on the Internet.

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5

Levrier, Claire. "Phytochemical and Biological Investigations of Cytotoxic Compounds from Australian Endemic Plants." Thesis, Griffith University, 2016. http://hdl.handle.net/10072/367364.

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The lack of a cure for advanced prostate cancer (PCa) highlights the need for better therapies to fight this disease, which is the second most common cause of cancer-related death in men. Nature is a rich source of potent anticancer agents, as 75% of the current drugs are derived from natural products, some being microtubule-targeting drugs like vinblastine and docetaxel. While proven to increase overall survival time of PCa patients, docetaxel treatment ultimately fails in part due to the development of drug resistance, presenting a major clinical challenge, given the limited number of altern

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6

GRECO, STEFANIA. "The effect of Phytochemical Compounds on Uterine Myometrial and Leiomyoma Cells." Doctoral thesis, Università Politecnica delle Marche, 2019. http://hdl.handle.net/11566/263604.

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Il fibroma uterino o leiomioma è il tumore benigno più comune che colpisce l’utero nelle donne in età fertile. I fibromi causano, dolore o pressione pelvica, menorragia ossia una perdita ematica mestruale abbondante nonché dolorosa, ed è una delle principali cause d’infertilità e aborti ricorrenti. I fibromi uterini, sono l’indicazione principale d’isterectomia. Nonostante, l'alta prevalenza di questa patologia nelle donne, la patogenesi dei leiomiomi uterini non è stata ancora del tutto chiarita. Recenti studi, hanno dimostrato che una dieta basata su composti fitochimici ha proprietà pr

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7

Perera, Muthukuttige. "Phytochemical analysis of two Australian native plants and their effects on chronic wound healing." Thesis, Queensland University of Technology, 2022. https://eprints.qut.edu.au/229994/1/Muthukuttige%20Madusha%20Nuwanthi_Perera_Thesis.pdf.

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Chronic wounds are a significant burden to national health services worldwide and a potential reason for patients’ declining quality of life. As such, this project focused on assessing the therapeutic effect of two Australian native plants, Alocasia macrorrhizos and Syncarpia hillii for their potential in chronic wound healing, through investigating their antibacterial, anti-inflammatory, and regenerative properties.

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8

Richmond, Oliver H. III. "Extraction, Purification and Evaluation of PRMT5-Inhibitory Phytochemical Compounds for the Treatment of Prostate Adenocarcinoma." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2019. http://digitalcommons.auctr.edu/cauetds/185.

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The development and advancement of prostate cancer is supported by a plethora of genetic and proteomic abnormalities, including events of post-translational modifications. The protein arginine methyltransferase 5 (PRMT5) enzyme regulates epigenetic events of histone modifications and protein post-translational modifications within protein signaling pathways. PRMT5 functions by catalyzing the symmetric dimethylation of terminal arginine residues on target protein substrates. Under abnormal conditions of overexpression and upregulation, PRMT5 methyltransferase activity constitutively drives the

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9

Tang, Sharon Shuk Lan. "Phytochemical and biochemical investigation of Ochna macrocalyx and Bupleurum fruitcosum - searching for NF-kB inhibitory compounds." Thesis, University College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406410.

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10

Okoh, Omobola Oluranti. "Chemical transformations and phytochemical studies of bioactive components from extracts of Rosmarinus officinalis L." Thesis, University of Fort Hare, 2010. http://hdl.handle.net/10353/354.

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Variations in the yield, chemical composition, antibacterial, and antioxidant properties of the essential oils of Rosmarinus officinalis L. cultivated in Alice, Eastern Cape of South Africa over a period of 12 months using the solvent-free microwave extraction and traditional hydrodistillation methods were evaluated. The GC-MS analyses of the essential oils revealed the presence of 33 compounds with 1,8-cineole, a-pinene, camphor, verbenone, bornyl acetate and camphene constituting about 80 percent of the oils throughout the period of investigation, with the solvent-free microwave extraction m

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11

Rasul, Mohammed Golam. "Phytochemical investigation of some medicinal plants transformative reaction on the isolated organic compounds and studied on their biological activities." Thesis, University of North Bengal, 2010. http://hdl.handle.net/123456789/1370.

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12

Nguyen, Thi Thu Tram. "Screening of mycosporine-like compounds in the dermatocarpon genus : phytochemical study of the lichen dermatocarpon luridum (WITH.) J.R Laundon." Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S177/document.

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Un criblage phytochimique à partir de quatre lichens saxicoles hydrophiles du genre Dermatocarpon a mis en évidence la présence inattendue de composés de type mycosporines dans ces chlorolichens. Leur présence a été confirmée dans des échantillons historiques d'herbiers couvrant une période de plus de 170 ans. Leur teneur était comprise entre 0,1 et 1,4 mg/g de lichen sec. Trois mycosporines ont été isolées de Dermatocarpon luridum collecté en Bretagne sur des rochers d'eau vive: deux mycosporines natives, la mycosporine glutaminol et la mycosporine glutamicol ainsi qu'un artéfact d'isolement,

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13

Uddin, Shaikh Jamal. "Cytotoxicity Screening of Bangladeshi Medicinal Plants and Isolation and structural Elucidation of Novel Anti-Cancer Compounds from Acrostichum aureum." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/365889.

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This thesis describes the cytotoxicity and phytochemical screening of 16 selected medicinal plants collected from the tidal forests of the coastal Sundarban and locations within the Khulna district of Bangladesh. The selected plants were successively extracted with n-hexane, dichloromethane, methanol and water. The methanol and aqueous extracts were then screened for cytotoxic activity (MTT assay) against one normal mouse fibroblast and three human cancer cell lines (gastric, colon and breast cancer). The results supported some of the traditional uses and reported cytotoxic activity for some o

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Colusso, Ariane Schneider. "PRODUÇÃO E CARACTERIZAÇÃO DE NANOCÁPSULAS CONTENDO TRANS-ANETOL E AVALIAÇÃO IN VITRO DA CAPACIDADE ANTIOXIDANTE." Centro Universitário Franciscano, 2016. http://www.tede.universidadefranciscana.edu.br:8080/handle/UFN-BDTD/545.

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Submitted by MARCIA ROVADOSCHI (marciar@unifra.br) on 2018-08-17T11:20:26Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissetacao_ArianeSchneiderColusso.pdf: 1387386 bytes, checksum: ca5b21fd4ec8eb3de7d6668c214ecd67 (MD5)<br>Made available in DSpace on 2018-08-17T11:20:26Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Dissetacao_ArianeSchneiderColusso.pdf: 1387386 bytes, checksum: ca5b21fd4ec8eb3de7d6668c214ecd67 (MD5) Previous issue date: 2016-01-08<br>The trans-anethole (TA) is an aromatic

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Takaidza, Samkeliso. "Phytochemical analysis and biological activities of crude extracts from selected Tulbaghia species." Thesis, Vaal University of Technology, 2018. http://hdl.handle.net/10352/434.

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PhD (Department of Biotechnology, Faculty of Applied and Computer Sciences), Vaal Universtiy of Technology<br>The genus Tulbaghia has been used in traditional medicine to treat various ailments such as fever, earache, tuberculosis and esophageal cancer. However, there is limited scientific evidence to support its use. Therefore the objectives of this study were to perform phytochemical analysis, investigate the antioxidant, antimicrobial, anticancer, immunomodulatory activities and toxicity of crude acetone and water extracts from selected Tulbaghia species. Standard methods were used for pr

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16

Canova, Érika Breda. "Eficiência de plantas taniníferas no controle de helmintos gastrintestinais de ovinos." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/64/64134/tde-11112016-091819/.

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Os endoparasitas têm demonstrado resistência aos principais anti-helmínticos. Por isso é necessário investigar estratégias sustentáveis, sendo uma das alternativas a utilização de plantas leguminosas (Fabaceae) no controle de nematóides. Objetivou-se avaliar a atividade anti-helmíntica de 17 extratos de plantas no teste de inibição da eclodibilidade dos ovos, teste de inibição de desembainhamento de larvas de Haemonchus contortus e o teste de motilidade do Caenorhabditis elegans, in vitro. As duas melhores plantas foram levadas para teste in vivo (Arachis pintoi cv Amarillo e Caesalpinia echin

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Silva, Claudia Tatiana Araujo da Cruz. "Análise fitoquímica, antioxidante e fitotóxica dos extratos de folhas de salvia officinalis l. sobre lycopersicon esculentum." Universidade Estadual do Oeste do Parana, 2016. http://tede.unioeste.br:8080/tede/handle/tede/261.

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Made available in DSpace on 2017-05-12T14:47:35Z (GMT). No. of bitstreams: 1 Claudia Tatiana_ silva.pdf: 2022908 bytes, checksum: a04e53fead9716247a3d90eaa7333faf (MD5) Previous issue date: 2016-01-18<br>Allelochemicalare substances present in plants, released into the environment that influence on the community, since the allelopathic potential of one plant can inhibit the development of others. Medicinal plants that have essential oils in their composition have typically been promising in weed control. Thus, this study evaluated the phytotoxic potential of dried leaves, extracts and essent

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18

Mangoba, Paula Maria Alexandre. "Prospecção de características fitoquímicas, antibacterianas e físico-químicas de portulaca oleracea l. (beldroega)." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/115207.

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A Portulaca oleracea L. (beldroega) possui propriedades antioxidantes e antimicrobianas, podendo ser utilizada como planta medicinal e alimento funcional. O estudo objetivou determinar: a composição centesimal e mineral da beldroega in natura; a intensidade da atividade de inibição bacteriana (IINIB) e a intensidade da atividade de inativação bacteriana (IINAB) das concentrações de 50, 25, 12.5 e 6.25 % de extratos alcoólicos da beldroega sobre diferentes inóculos bacterianos de interesse em alimentos (Staphylococcus aureus, Escherichia coli, Salmonella Enteritidis e Enterococcus faecalis), pe

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19

Lima, Karisia Sousa Barros de. "Phytochemical Study of Two Species of Hyptis from Northeast of Brazil: Hyptis carvalhoi Harley and Hyptis crassifolia Mart. ex Benth. and Anticancer Activity of the Isolated Compound." reponame:Repositório Institucional da UFC, 2014. http://www.repositorio.ufc.br/handle/riufc/18345.

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LIMA, Karisia Sousa Barros de. Estudo Fitoquímico de Duas Espécies de Hyptis do Nordeste do Brasil: Hyptis carvalhoi Harley e Hyptis crassifolia Mart. ex Benth. e Atividade Anticâncer dos Compostos Isolados. 2014. 393 f. Tese (Doutorado em química)- Universidade Federal do Ceará, Fortaleza-CE, 2014.<br>Submitted by Elineudson Ribeiro (elineudsonr@gmail.com) on 2016-06-02T18:50:49Z No. of bitstreams: 1 2014_tese_ksblima.pdf: 15717636 bytes, checksum: 462d1018effc4c80bfd29e17576abf17 (MD5)<br>Approved for entry into archive by José Jairo Viana de Sousa (jairo@ufc.br) on 2016-07-14T23:21:49Z (GMT

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20

Silva, Analú Barbosa da. "Caracterização antibacteriana, química e fitoquímica de flores de Hibiscus rosa-sinensis L. (mimo-de-vênus) e Hibiscus syriacus L. (hibisco-da-síria) como fonte de alimento." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2014. http://hdl.handle.net/10183/101498.

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O Hibiscus rosa-sinensis L. e o Hibiscus syriacus L., da família Malvaceae são utilizados na área ornamental, mas nos últimos anos vem ganhando espaço na área alimentícia como flores comestíveis. Alguns estudos demonstram o potencial antibacteriano destas variedades frente a diversos microrganismos e sobre sua composição nutricional e fitoquímica há poucas pesquisas. Este trabalho teve por objetivo analisar a intensidade de atividade de inibição (IINIB) e a inativação bacteriana (IINAB) in vitro dos dois extratos alcoólicos das flores dos hibiscos e a relação com os polifenóis e antocianinas,

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Dambros, Juliele Ilone. "Estabilidade de compostos potencialmente bioativos e alterações de qualidade em frutos e produtos de pimenta (Capsicum spp.)." Universidade Federal de Pelotas, 2014. http://repositorio.ufpel.edu.br:8080/handle/prefix/3089.

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Submitted by Gabriela Lopes (gmachadolopesufpel@gmail.com) on 2016-10-10T17:23:40Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) DAMBROS, JULIELE ILONE. DISSERTAÇÃO. 2014.pdf: 2962958 bytes, checksum: 34d825a9cf92ff3104e711a2674f58f6 (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2016-10-11T20:49:06Z (GMT) No. of bitstreams: 2 DAMBROS, JULIELE ILONE. DISSERTAÇÃO. 2014.pdf: 2962958 bytes, checksum: 34d825a9cf92ff3104e711a2674f58f6 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)<br>

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Talag, Agela Hussain Mohammed. "Phytochemical investigation and biological activities of Sanicula europaea and Teucrium davaeanum : isolation and identification of some constituents of Sanicula europaea and Teucrium davaeanum and evaluation of the antioxidant activity of ethanolic extracts of both plants and cytotoxic activity of some isolated compounds." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/14482.

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The aim of this research was to investigate the phytochemistry of two species Sanicula europaea and Teucrium davaeanum which are traditionally used in treatment of wounds. Four compounds were isolated from the 80% methanolic extract of S. europaea; bis-(2-ethylhexyl) phthalate (1), palmitic acid (2), rosmarinic acid (3), saniculoside N (4). Compounds 1 and 2 were isolated for the first time from this species. The structure elucidation of the isolated compounds was on the basis of 1D, 2D NMR spectroscopy and mass spectrometry measurements. Two compounds were isolated from the crude glycosides e

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23

Sá, Giulian César da Silva. "Caracterização nutricional, antinutricional, bioquímica e atividades biológicas de sementes de Sesbania Virgata (cav.) pers." Universidade Federal da Paraíba, 2017. http://tede.biblioteca.ufpb.br:8080/handle/tede/9817.

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Submitted by Leonardo Cavalcante (leo.ocavalcante@gmail.com) on 2018-04-23T23:19:25Z No. of bitstreams: 1 Arquivototal.pdf: 1967881 bytes, checksum: 7ca8d86d26370955fcc5937ad9344abc (MD5)<br>Made available in DSpace on 2018-04-23T23:19:25Z (GMT). No. of bitstreams: 1 Arquivototal.pdf: 1967881 bytes, checksum: 7ca8d86d26370955fcc5937ad9344abc (MD5) Previous issue date: 2017-05-19<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Sesbania virgata is a shrub belonging to a family Leguminosae whose fruit presents seeds with high protein content. Considering the potential

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SAMRIDHI. "Molecular dynamics simulation studies of matrix metalloproteinases MMP2 and MMP9 and computer aided drug designing using phytochemicals as their potential inhibitors." Thesis, 2015. http://dspace.dtu.ac.in:8080/jspui/handle/repository/14351.

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Matrix metalloproteinases (MMPs), also designated matrixins, hydrolyze components of the extracellular matrix. These proteinases play a central role in many biological processes, such as embryogenesis, normal tissue remodeling, wound healing, and angiogenesis, and in diseases such as atheroma, arthritis, cancer, and tissue ulceration (Visse et al.,2003). MMPs, especially those capable of cleaving type IV basement membrane collagen (MMP-2 and -9) were considered to be ideal targets for drug development.Two gelatinases, MMP-2 (72-kDa gelatinase) and MMP-9 (92-kDa gelatinase), are key proteina

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Pereira, Carolina Velhinho. "Effect of Citrus Bioactive Compounds on Targeting Human Colorectal Cancer Stem Cells." Master's thesis, 2016. http://hdl.handle.net/10362/25157.

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Recently, there has been an increase in the interest of the application of natural extract for cancer prevention and treatment, where phenolic compounds are associated with a high effectiveness in prevention and treatment of the disease. One of the promising targets for cancer therapy is the cancer stem cells population, which has been recognized as responsible for tumor initiating, relapse and chemo-resistance. The main goal of this thesis was to evaluate the chemotherapeutical potential of polymethoxylated flavones (PMFs) from orange peel extracts, using HT29 3D colorectal cancer model. Thi

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Bhuyan, Deep Jyoti. "Phytochemicals derived from Australian eucalypts as anticancer agents for pancreatic malignancies." Thesis, 2018. http://hdl.handle.net/1959.13/1388005.

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Research Doctorate - Doctor of Philosophy (PhD)<br>The poorest prognostic outcome for pancreatic cancer (PC) patients, among all gastrointestinal malignancies, can be attributed to the molecular heterogeneity and lack of specific therapeutic strategies. The emergence of resistance against the common chemotherapeutic drug gemcitabine has also been widely reported. Several studies have demonstrated improved efficacy using gemcitabine in conjunction with plant polyphenolics and antioxidants for PC treatment. This suggests that plant secondary metabolites should be investigated further in a search

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Sobers, Hana Shatara. "Accessing The Bioavailability Of Phytochemicals In Caco-2 Cell Model And Developing A Sensitive Method For The Detection And Quantification Of These Compounds." 2012. https://scholarworks.umass.edu/theses/950.

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Numerous studies have found certain unmethylated phytochemicals to possess anti-carcinogenic activity; however, they have been associated with poor oral bioavailability which is a major limiting factor in their usage in chemopreventative treatment. The purpose of this study was to investigate if methylation of a compound would affect bioavailability, in terms of transport and permeability, in a Caco-2 cell model as well as the effect of cell viability and cellular uptake in human colon cancer cell lines. Furthermore, a new analytic method using reversed-phase high performance liquid chromatogr

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Zikalala, Bongekile Octavia. "The chemical composition of baby spinach (Spinacia oleracea L,) as affected by nitrogen, phosphorus and potassium nutrition." Diss., 2014. http://hdl.handle.net/10500/18674.

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Baby spinach (Spinacia oleracea L.) is considered to be the one of the extremely nutritious vegetables, rich both in phytochemicals and core nutrients. Nowadays, phytochemicals in plants are raising interest in consumers for their roles in the maintenance of human health. Variation in content of bioactive compounds and core nutrients is the main concern in vegetable production. Factors such as cultural practices specially fertilization, may affect the nutritional and medicinal properties of the plants Therefore, three parallel trials for NPK to investigate the response of baby spinach leaves

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Setshedi, Itumeleng Bridgette. "Phytochemical isolation of compounds from the plant sceletium tortuosum." Diss., 2012. http://hdl.handle.net/10500/13237.

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Traditionally, Sceletium tortuosum has been used as a medicine and for social and spiritual purposes. The genus is distributed in the south-western parts of South Africa. This project phytochemically analysed and characterised Sceletium plant extracts and determined if any extract showed anti-malarial properties. Extracts were prepared in ethanol and methanol and various compounds were purified using column chromatography with hexane and ethyl acetate as mobile phase. The structure of isolated compounds, including mesembrine, pinitol, sucrose, mesembrenone and obtusalin, was confirmed usi

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Ngwenya, Nomcebo Marcia. "Biological and phytochemical screening of major compounds in Cephalanthus natalensis." Thesis, 2012. http://hdl.handle.net/10210/4673.

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M.Sc.<br>Cephalanthus natalensis of the Rubiaceae family of plants is used in traditional medical systems. Different parts of this shrubby plant are used to treat different ailments. In this study, the use of C. natalensis for medicinal purposes was investigated. Plant materials (leaves, bark and fruits) were collected from different localities in Swaziland. Extraction of phytochemicals in C. natalensis was done by maceration in four solvents of increasing polarities: hexane, dichloromethane, ethyl acetate and methanol. Amino acids and alkaloids were also extracted in boiling water and mild ac

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Puwavicheanchai, Prokprae, and 卜瑋彩. "Phytochemical compounds and chemoprotective effect of dried Siraitia grosvenorii fruit extracts." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/42275366936480282846.

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碩士<br>國立屏東科技大學<br>熱帶農業暨國際合作系<br>102<br>The fruits of Siraitia grosvenorii (Luo Han Kuo), belonging to family Cucurbitaceae, are traditional Chinese medicine and edible plant cultivated in south-western China. S. grosvenorii fruit extracts have been approved generally recognized as safe (GRAS) status by the Food and Drug Administration of the United States (USFDA). The effects of extraction solvents (hot water and 80% ethanol) in dried fruit flesh and peel extraction and effects of yeast strains (Saccharomyces bayanus and S. cerevisiae) and fermentation time in dried fruit flesh and peel fermen

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Zikalala, Bongekile Octavia. "Chemical composition of baby spinach (Spinacia oleracea L.) as affected by nitrogen, phosphorous and potassium nutrition." Diss., 2014. http://hdl.handle.net/10500/18762.

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Baby spinach (Spinacia oleracea L.) is considered to be the one of the extremely nutritious vegetables, rich both in phytochemicals and core nutrients. Nowadays, phytochemicals in plants are raising interest in consumers for their roles in the maintenance of human health. Variation in content of bioactive compounds and core nutrients is the main concern in vegetable production. Factors such as cultural practices specially fertilization, may affect the nutritional and medicinal properties of the plants Therefore, three parallel trials for NPK to investigate the response of baby spinach leaves

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33

Wangchuk, Phurpa. "Phytochemical analysis, bioassays and the identification of drug lead compounds from seven Bhutanese medicinal plants." Thesis, 2014. http://ro.uow.edu.au/theses/4076/.

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The Bhutanese traditional medicine (BTM) has been integrated with biomedicine since 1967 and serves as one of the important health care delivery systems in Bhutan. Therefore, the need to improve its quality through scientific studies have become paramount. In our efforts to address this important issue, we authenticated the botanical names of low altitude medicinal plants, determined the major classes of phytochemicals of 25 selected species, evaluated the bioactivities of the crude extracts of seven of them, and finally isolated the phytochemicals from six of these plants. We have established

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Fernandes, Tomásia Micaela Gomez. "Exploring Pavlova pinguis and Hemiselmis cf. andersenii as natural sources of high-value lipids." Doctoral thesis, 2022. http://hdl.handle.net/10400.13/4034.

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A crescente demanda dos consumidores por fontes naturais e sustentáveis de compostos de valor acrescentado tem levado as comunidades científica e industrial a explorar a biodiversidade das microalgas e a sua diversidade química. Na bioprospecção de microalgas para a produção integrada de biomassa e compostos de valor acrescentado, diversos desafios são encontrados, como o cultivo de novas espécies, a identificação de novas moléculas e a otimização das condições de cultivo para a produção dos fitoquímicos desejados. Este estudo investiga o potencial de duas microalgas inexploradas,

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Du, Toit Karen. "A phytochemical investigation of members of the hyacinthaceae family and biological screening of homoisoflavanones and structurally related compounds." Thesis, 2004. http://hdl.handle.net/10413/2259.

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The Hyacinthaceae family is richly represented in southern Africa. Of the five subfamilies, three are found in southern Africa. These are the Urgineoideae (URG), Ornithogaloideae (ORN) and the Hyacinthoideae (HYA). The overview of Pfosser and Speta (1999), revealed chemotaxonomic trends at a subfamily level for the Hyacinthaceae family of the Flora of southern Africa region. Homoisoflavanones were found to define the Hyacinthoideae subfamily whilst the Ornithogaloideae subfamily and the Urgineoideae subfamily are defined by steroidal compounds namely, cholestane glycosides and bufadienolide gl

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Santos, Joana Filipa Morais. "Bioatividade de desperdícios alimentares." Master's thesis, 2018. http://hdl.handle.net/10284/6658.

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O conceito de sustentabilidade resume-se à noção de desenvolvimento económico, social e ambiental, de forma a não provocar danos significativos ao ambiente e aos recursos naturais existentes. Nos dias de hoje, o crescimento da população é uma das questões mais preocupantes, sendo indispensável repensar o problema dos desperdícios originados pelas indústrias agroalimentares. Anualmente, estas indústrias desperdiçam toneladas de resíduos que pouca ou nenhuma utilização têm. Contudo, grande parte destes desperdícios alimentares contém quantidades consideráveis de compostos bioatividade, cu

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Van, Wyk Anna Susanna. "Phytochemical evaluation of Curtisia dentata (Burm.f.) C.A.Sm. stem bark and seasonal and geographical region variability." Thesis, 2020. http://hdl.handle.net/10500/27038.

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The stem bark of the protected tree species, Curtisia dentata (Burm. f.)C.A.Sm., is one of the most popular plant species harvested and traded at traditional medicine markets in South Africa. The overexploitation of C. dentata trees lead to a “Near Threatened” conservation status and the population trend is portrayed as “declining”. In the KwaZulu-Natal Province of South Africa, C. dentata is completely conservation dependent. This study is not based on drug discovery or toxicological studies, but on the concern that the stem bark of C. dentata trees are harvested, prepared into remedies and

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Boukandou, Mounanga Marlaine Michele. "Investigation of plants used in Gabonese traditional medicine for the treatment of opportunistic infections caused by HIV." Thesis, 2019. http://hdl.handle.net/11602/1416.

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PhD (Microbiology)<br>Department of Microbiology<br>Background: Currently, Human Immunodeficiency Virus/ Acquired Immune Deficiency Syndrome (HIV/AIDS) is one of the deadliest diseases in the world. In Gabon, the prevalence is estimated at 4.1%. Because of the several side effects of highly active antiretroviral therapy on the health of people living with HIV, an emphasis on the utilization of based plant treatments have been noticed highlighted with testimonies of patient health improvement. That led researchers to conduct ethnobotanical surveys aiming at reporting medicinal plants used

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Tseng, Chia-Ling, and 曾嘉玲. "To study anticancer effect of a novel compound Yao-ram-2-7 in the presence or absence of phytochemical curcumin on human hepatocellular carcinoma cells and to identify other biological function of Yao-ram-2-7 using Connectivity Map." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/51336614462012391675.

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碩士<br>國立臺灣師範大學<br>人類發展與家庭學系<br>101<br>Hepatocellular carcinoma (HCC) is the fifth most common malignancy worldwide. More than 75% cases of HCC occur in the Asia-Pacific region. High mortality of HCC is due to the difficulty in diagnosis and poor prognosis. Chemotherapy is a traditional choice for inoperable HCC, whereas drug resistant limits the therapeutic effect. Thus, there is an urgent need to develop new potential drugs for HCC. Our research group has synthesized a series of compounds for anti-cancer screening using MTT assay. Yao-ram-2-7 is one of them significantly inhibits the growth o

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