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Dissertations / Theses on the topic 'Phytochemicals - Therapeutic use'

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1

Zhang, Qi. "The study of novel dioxin antagonist-euxanthone and its derivatives." HKBU Institutional Repository, 2003. http://repository.hkbu.edu.hk/etd_ra/507.

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2

Xiao, Jia, and 肖佳. "Protective mechanisms of garlic and wolfberry derivatives on acute and chronic liver injury animal models." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/193039.

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Liver is one of the most important organs in the body that maintains the homeostasis of metabolism, immunity, detoxification and hematopoiesis. A large number of acute and chronic intoxications and diseases can influence the normal functions of the liver, leading to irreversible liver damage and even cancer. Currently, applying herbs or herbal derivatives in the prevention and therapy of acute and chronic liver injury receive numerous attentions since they hold great potentials as food supplements in the treatment strategy of liver injuries. There were two major hypotheses of this current work
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3

Lee, Tak-wing Davy, and 李德榮. "Effect of garlic derivative s-allylcysteine (SAC) on the growth of human esophagealand nasopharyngeal carcinoma cells." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B45011278.

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4

Ballentine, Regina. "Chemical Characterization of Pseudognaphalium obtusifolium by Gas Chromatography - Mass Spectrometry (GC-MS) to Assess Potential Therapeutic Phytochemicals and Toxicological Concerns Using Simulated Use Conditions." VCU Scholars Compass, 2019. https://scholarscompass.vcu.edu/etd/6052.

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Chemical Characterization of Pseudognaphalium obtusifolium by Gas Chromatography – Mass Spectrometry (GC-MS) to Assess Potential Therapeutic Phytochemicals and Toxicological Concerns Using Simulated Use Conditions By Regina Ballentine Virginia Commonwealth University, 2019 Director: Sarah C. Rutan, Professor, Department of Chemistry Currently, there is an increasing demand for natural therapies and herbal products to treat various ailments. It is generally believed that natural therapies have fewer side-effects than traditional western medicine; however, they are often used in different stre
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5

Mngeni, Nasipi Zamanala. "Bioactive compounds from selected medicinal plants used in antidiabetic treatment." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2665.

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Thesis (MTech (Chemistry))--Cape Peninsula University of Technology, 2017.<br>The continued use and popularity of plant-based traditional medicine demands scientific validation of the therapeutic potential of the medicinal plants used in disease management and treatment. These medicinal plants are to be evaluated for phytochemical constituents and pharmacologically screened for their bioactivity and include the isolation and identification of their bioactive compounds. The diabetes tea and its eight individual plants constituents were collected from Sing Fefur Herbs in McGregor, Western Cape.
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6

Zhang, Zhu. "Exploration of the anticancer mechanisms of novel chemotherapeutic adjuvants involving autophagy and immune system reprogramming in the treatment of pancreatic cancer." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/755.

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Pancreatic cancer is known to be one of the most life-threatening cancers characterized by aggressive local invasion and distant metastasis. The high basal level of autophagy in pancreatic cancer may be responsible for the low chemotherapeutic drug response rate and poor disease prognosis. However, the clinical application of autophagy inhibitors was unsatisfactory due to their toxicity and minimal single-agent anticancer efficacy. Hence, oncologists begin to consider the tumor microenvironment when exploring new drug targets. In the present study, the anti-tumorigenic mechanisms of two major
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7

Adefuye, Ogheneochuko Janet. "Anti-diabetic and phytochemical analysis of sutherlandia frutescens extracts." Thesis, Nelson Mandela Metropolitan University, 2016. http://hdl.handle.net/10948/3549.

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In Africa, the importance of medicinal plants in folklore medicine and their contribution to primary healthcare is well recognized. Across the continent, local herbal mixtures still provide the only therapeutic option for about 80% of the population. The vast floral diversity and the intrinsic ethnobotanical knowledge has been the backbone of localized traditional herbal medical practices. In Africa, an estimated 5400 of the 60000 described plant taxa possess over 16300 therapeutic uses. Similarly, with a therapeutic flora comprising of approximately 650 species, herbal medical practitioners i
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8

Wang, Jingrong. "Phytochemical and pharmacological studies of the root of ilex pubescens." HKBU Institutional Repository, 2008. http://repository.hkbu.edu.hk/etd_ra/899.

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9

Sagbo, Idowu Jonas. "Phytochemical analysis and antibacterial properties of aqueous and ethanol extracts of Brachylaena elliptica (Thurb.) dc. and Brachylaena ilicifolia (Lam.) Phill & Schweick." Thesis, University of Fort Hare, 2015. http://hdl.handle.net/10353/d1021289.

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Resistance of human pathogenic bacterial strains results in selective pressure against known antibiotic. However, plant derived compounds that possess antibacterial potential are currently being investigated for treatment of wound infections in diabetic patients as they are inexpensive and non-toxic. Hence, this dissertation was designed to evaluate two medicinal plants (Brachylaena elliptica and Brachylaena ilicifolia) traditionally used in the treatment of various diseases such as diabetes, and its secondary complications in diabetic patients. The in vitro antioxidant activity of both plants
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10

Harris, Taahir. "Bambara groundnut (Vigna subterranean) from Mpumalanga province of South Africa: phytochemical and antimicrobial properties of seeds and product extracts." Thesis, Cape Peninsula University of Technology, 2017. http://hdl.handle.net/20.500.11838/2789.

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Thesis MTech (Food Technology))--Cape Peninsula University of Technology, 2017.<br>Bambara groundnut (Vigna subterranea) an indigenous legume cultivated in Sub-Saharan Africa has been proclaimed to have medicinal properties from communities and in rural areas. However, there is not enough scientific information to validate these claims. Therefore, this study aimed to identify possible medicinal properties of Bambara groundnut (BGN), by analysing the phytochemical and antimicrobial properties of BGN seed and product extracts from Mpumalanga province within South Africa. The BGN extracts (70% me
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11

Manyi-Loh, Christy E. "Antibacterial and phytochemical studies of selected South African honeys on clinical isolates of Helicobacter pylori." Thesis, University of Fort Hare, 2012. http://hdl.handle.net/10353/d1001056.

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Infection with Helicobacter pylori has been associated with the pathogenesis of numerous stomach and gastroduodenal diseases that pose threats to public health. Eradicaftion of this pathogen is a global challenge due to its alarming rate of multidrug resistance. Consequently, to find an alternative treatment, the search is increasingly focused on new antimicrobial product from natural sources including honey. Honey has been used as medicine in several cultures since ancient time due to its enormous biomedical activities. Its beneficial qualities have been endorsed to its antimicrobial, antioxi
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12

Nethathe, Bono Bianca. "Bioactivity and phytochemical analysis of Hydnora Africana on some selected bacterial pathogens." Thesis, University of Fort Hare, 2011. http://hdl.handle.net/10353/d1001063.

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Abstract Medicinal plants have been for long remedies for human diseases because they contain components of therapeutic value. The growing problem of antibiotic resistance by organisms demands the search for novel compounds from plant based sources. The present study was aimed at evaluating the bioactivity and phytochemical analysis of Hydnora africana on clinical and standard strains of Helicobacter pylori (PE 252C and ATCC 43526), Aeromonas hydrophila ATCC 35654, and Staphylococcus aureus NCT 6571 in an effort to identify potential sources of cheap starting materials for the synthesis of new
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13

Chaovanalikit, Arusa 1974. "Cherry phytochemicals." Thesis, 2003. http://hdl.handle.net/1957/27184.

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The distribution of anthocyanin pigments and polyphenolics of sweet (Prunus avium) and sour cherries (Prunus cerasus) were determined by Ultraviolet- Visible (UV-Visible) spectrophotometry and High Performance Liquid Chromatography with photodiode array detector (HPLC-DAD). Their antioxidant properties were determined by Oxygen Radical Absorbance Capacity (ORAC) and Ferric Reducing Antioxidant Power (FRAP). The effect of frozen storage, canning, and brining on those properties was measured. Experiments were conducted on three sweet cherry cultivars; Bing, Rainier, Royal Ann and one sour cherry
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14

"Anticancer effects of the phytochemicals from Schefflera heptaphylla." 2007. http://library.cuhk.edu.hk/record=b5893103.

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Yeung Chung Man.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2007.<br>Includes bibliographical references (leaves 83-97).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Abstract (Chinese) --- p.iv<br>Acknowledgements --- p.vii<br>Table of contents --- p.ix<br>List of figures --- p.xii<br>List of tables --- p.xiv<br>List of abbreviations --- p.xv<br>Chapter Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- General Introduction --- p.1<br>Chapter 1.2 --- Literature Review --- p.5<br>Chapter 1.2.1 --- Cancer and melanoma --- p.5<br>Chapter 1.2.2 --- Anticance
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15

"Effect of phytochemicals on estrogen biosynthesis in human breast cancer and placental cells." Thesis, 2005. http://library.cuhk.edu.hk/record=b6074044.

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A breast cancer cell line stably transfected with the CYP19 gene had been employed for aromatase inhibition. Among the phytochemicals tested, the major dietary flavonoids, such as genistein and daidzein, produced very weak inhibition. On the other hand, the red clover isoflavone biochanin A, the hydroxychalcone butein and the red grape phytoalexin resveratrol were found to be effective aromatase inhibitors. Cell proliferation assay had shown that they could inhibit ER-positive cell proliferation induced by testosterone, and the inhibitory effect was specifically attributed to the reduction of
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16

Ndhlala, Ashwell Rungano. "Pharmacological, phytochemical and safety evaluaton of commercial herbal preparations common in South Africa." Thesis, 2009. http://hdl.handle.net/10413/729.

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17

"Pharmacological and phytochemical investigations on selected Chinese herbs with regards to their anti-diabetic activities." 2004. http://library.cuhk.edu.hk/record=b5892121.

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by Lau Chun Hong.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.<br>Includes bibliographical references (leaves 179-195).<br>Abstracts in English and Chinese.<br>Abstract --- p.i<br>Abstract in Chinese 摘要 --- p.iv<br>Acknowledgements --- p.vi<br>Table of Contents --- p.vii<br>List of Abbreviations --- p.xiii<br>List of Figures --- p.xvi<br>List of Tables --- p.xviii<br>Publications --- p.xix<br>Chapter Chapter1 --- Introduction --- p.1<br>Chapter 1.1 --- Epidemiology of Diabetes Mellitus --- p.1<br>Chapter 1.2 --- Definition of Diabetes Mellitus --- p.2<br>Chapter 1.3 -
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18

"Phytochemical and biological studies of phyllanthus species: effects on hepatitis B virus." Thesis, 2005. http://library.cuhk.edu.hk/record=b6074039.

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A number of recent research studies have been done on different species of the plants of the genus Phyllanthus. The plants are widely distributed in most tropical and subtropical countries and have long been used for the treatment of liver diseases in China and India.<br>Hepatitis B virus (HBV) is a major pathogen of human viral hepatitis. It has been estimated that 350 million people are chronic carriers of HBV throughout the world. Increasing evidence indicates that persistent viral infection of the liver is associated with cirrhosis and hepatocellular carcinoma. Hepatitis B virus belongs to
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19

"In vitro and in vivo mechanistic studies of the wound-healing effects of Astragali Radix and phytochemical analysis of its active fractions/components isolated using bioassay-guided fractionation." 2013. http://library.cuhk.edu.hk/record=b5884429.

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Lai, Kwok Kin.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2013.<br>Includes bibliographical references (leaves 229-251).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.
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