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Relevant bibliographies by topics / Phytochemistry and Pharmacological Aspects / Dissertations / Theses

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Dissertations / Theses on the topic 'Phytochemistry and Pharmacological Aspects'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Kachura, Alexandra. "An Ethnobotanical, Pharmacological, and Phytochemical Analysis of Achillea millefolium L. by Parts." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38516.

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This thesis investigated the pharmacology and phytochemistry of Achillea millefolium L. (yarrow) flowers, roots, stems, and leaves based on ethnobotanical reports in North America, with a focus on applications in a respiratory model. Seasonal changes in the phytochemical profile of yarrow were also assessed. A comprehensive dataset of medicinal Asteraceae was created after collecting ethnobotanical reports from the Native American Ethnobotany (NAEB) database. Using residual and binomial analyses, 14 tribes of Asteraceae were quantitatively evaluated and ranked within ten therapeutic categorie

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2

Bjartmar, Lisa. "Pharmacological and Developmental Aspects on Neuronal Plasticity." Doctoral thesis, Linköpings universitet, Geriatrik, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-51450.

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Neuronal plasticity means the ability of the brain, its cells and networks to adapt and adjust to new challenges, a process which is ongoing throughout life. The goal of this thesis was to gain better understanding of the molecular events that follow different types of stimulations of brain structures such as the hippocampus, a key region for cognitive functions with overriding control on the corticosteroid system. A better knowledge of the mechanisms involved in neuronal plasticity is fundamental in the development of strategies for improving health in patients suffering from major depression

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3

Burri, Christian. "Pharmacological aspects of the trypanocidal drug melarsoprol /." [S.l. : s.n.], 1994. http://www.gbv.de/dms/bs/toc/159096111.pdf.

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4

Garford, M. V. "Biochemical and pharmacological aspects of depressive disorders." Thesis, University of Nottingham, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384286.

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5

Törneke, Karolina. "Pharmacological aspects of adrenoceptor drugs in the horse /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5431-X.pdf.

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6

Khalaf, Laila Fadhel. "Toxicological and pharmacological aspects of some aromatase inhibitors." Thesis, Cardiff University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389975.

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7

Nelson, Mark 1957. "Aspects of pharmacological management of hypertension in general practice." Monash University, Dept. of Epidemiology and Preventive Medicine, 2002. http://arrow.monash.edu.au/hdl/1959.1/7923.

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8

Schwieler, Lilly. "Endogenous kynurenic acid and schizophrenia : physiological and pharmacological aspects /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-704-9/.

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9

Tuninger, Eva. "Depot neuroleptic maintenance treatment clinical, pharmacological and neuropsychological aspects /." Lund : Dept. of Psychiatry, Lund University, University Hospital MAS, 1997. http://catalog.hathitrust.org/api/volumes/oclc/40281424.html.

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10

Husby, Kristin Moksnes. "Optimizing opioid treatment for cancer pain : clinical and pharmacological aspects." Doctoral thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for sirkulasjon og bildediagnostikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-17223.

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Smerter er et fryktet symptom hos pasienter med kreft og deres pårørende. 80 % av pasienter med langtkommet kreft opplever kreftsmerter, og hele 10-30 % opplever smerte og/eller uakseptable bivirkninger til tross for behandling med et sterkt opioid som for eksempel morfin. Hos disse pasientene er et bytte til et annet opioid som metadon et behandlingsalternativ. Mange strategier for opioid-bytte til metadon er foreslått, men ingen randomiserte studier eksisterer. Et alternativ er stopp-og-start-metoden hvor en starter rett på ny metadondose samtidig som det første opioidet avsluttes. Det er he

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11

Power, Kevin George. "Pharmacological and psychological aspects of anxiety management in primary care." Thesis, University of Stirling, 1989. http://hdl.handle.net/1893/21527.

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Pilot Study: a) 21 Generalised Anxiety Disorder (GAD) patients were treated double-blind with either diazepam or placebo for 6 weeks. This active treatment period was preceded by one-week single-blind placebo 'wash-in', and followed by two-week single-blind 'washout'. Results showed that diazepam used in moderate doses for 6 weeks produced anxiety recurrence and withdrawal symptoms. b) 10 GAD patients were randomly allocated to Cognitive-Behaviour Therapy (CBT) and compared with the above diazepam and placebo groups. All treatments were balanced for degree of Psychologist/patient contact. At c

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12

Serreli, Riccardo. "Pharmacological aspects of the inhibition of mammalian respiratory complex I." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/273222.

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Mitochondrial complex I, a large respiratory enzyme located in the inner mitochondrial membrane, catalyses electron transfer from NADH to ubiquinone while concomitantly translocating protons across the membrane to sustain ATP synthesis. A crucial aspect of the pharmacology of complex I is drug-induced mitochondrial dysfunction, particularly its role in liver toxicity. Complex I inhibition causes an energy deficit and can lead to adverse changes in the status of the mitochondrial [NADH]/[NAD+] pool and increased reactive oxygen species production, causing widespread damage. A library of molecul

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13

Bäckryd, Emmanuel. "The Cerebrospinal Fluid in Severe Pain Conditions : Clinical, Pharmacological and Proteomic Aspects." Doctoral thesis, Linköpings universitet, Avdelningen för samhällsmedicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-121494.

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The treatment of both cancer pain and non-cancer chronic pain is still suboptimal. The overall aim of this PhD thesis was to conduct translational pain research at the interface between clinical pain medicine and the field of human proteomics, using the practice of intrathecal analgesia at our institution as a starting point. Hence, the cerebrospinal fluid (CSF) is at the centre of the present dissertation, both as a target for infusing analgesics (Papers I and II – clinical and pharmacological aspects) and as an important biofluid for human biomarker studies (Papers III and IV – proteomic asp

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14

Josefsson, Kenneth. "Antimicrobial prophylaxis of bacteraemia in oral surgery pharmacological, toxicological and microbiological aspects /." Stockholm : Dept. of Oral Surgery, Karolinska Institutet, 1985. http://catalog.hathitrust.org/api/volumes/oclc/12018190.html.

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15

Ernestam, Sofia. "Rheumatoid arthritis : pharmacological modulation of cytokines - aspects of clinical response and endocrine regulation /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-628-X/.

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16

Kimura, Takashi. "Studies on pharmacological activities of the cauliflower mushroom Sparassis crispa." Kyoto University, 2013. http://hdl.handle.net/2433/180630.

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17

Tome, de la Granja Maria Begona. "Rapid symptomatic treatment in major depression : clinical, pharmacological and economic aspects of a novel regime." Thesis, King's College London (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266648.

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18

Alkamal, Imad [Verfasser]. "Pharmacological unmasking of epigenetically regulated genes in renal cell carcinomas under clinical chemistry aspects / Imad Alkamal." Berlin : Freie Universität Berlin, 2014. http://d-nb.info/1060367823/34.

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19

Hafiz, Taghreed. "Molecular, biochemical and pharmacological characterisation of Mycobacterium tuberculosis cytochrome bd-I oxidase : a putative therapeutic target." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/12633/.

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Tuberculosis (TB) remains one of the most devastating diseases in humans. Nowadays, tuberculosis therapy is not sufficient to control the TB epidemic and only lasts for 6 months to cure patients and prevent relapse; therefore, the treatment of Mycobacterium tuberculosis (Mtb) is particularly challenging (1). New antibiotics, mainly those that are derived from new chemical classes, are more likely to be more effective against resistant strains. Moreover, expanding the knowledge of the mode of action of drugs has important implications in tackling TB. Only empirical approaches can be adopted in

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20

Hassouna, Magdy M. "Studies on the physiological and pharmacological aspects of the lower urinary tract in normal and following spinal lesion." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=71986.

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The mechanisms implicated in voiding and continence are far from being settled in the normal as well as in neurogenic bladder dysfunction. Understanding these mechanisms is an essential step in the management of the bladder dysfunction secondary to neurological lesions. In the course of our studies, we demonstrated the existence of a fine coordination "synergism" between the several components of the lower urinary tract i.e., detrusor, proximal urethral muscle and periurethral striated muscles. This synergism is found to be responsible for adequate bladder emptying during voiding in the animal

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21

Innala, Lena. "Early rheumatoid arthritis aspects of severity and co-morbidity." Doctoral thesis, Umeå universitet, Reumatologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88477.

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Background Rheumatoid arthritis (RA) is a systemic progressive destructive joint disease with an increased risk for co-morbidity and premature death if untreated. Cardiovascular disease (CVD) is the main cause of death but also other co-morbid conditions contribute to the patient’s shorter life expectancy. Inflammation is important for the development of CVD, but knowledge of its relationship with other co-morbidities is sparse. Early disease modifying anti rheumatic drugs (DMARDs) can suppress disease activity and improve the long-term outcome. The aim of this thesis was to evaluate prospecti

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22

Nordquist, Jenny. "Semicarbazide-sensitive amine oxidase and vascular complications in diabetes mellitus : Biochemical and molecular aspects." Doctoral thesis, Uppsala University, Pharmacology, 2002. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2566.

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<p>Plasma activity of the enzyme semicarbazide-sensitive amine oxidase (SSAO; EC.1.4.3.6) has been reported to be high in disorders such as diabetes mellitus, chronic congestive heart failure and liver cirrhosis. Little is known of how the activity is regulated and, consequently, the cause for these findings is not well understood. Due to the early occurrence of increased enzyme activity in diabetes, in conjunction with the production of highly cytotoxic substances in SSAO-catalysed reactions, it has been speculated that there could be a causal relationship between high SSAO activity and vascu

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23

Cheung, Kwok-ho Alvin, and 張國豪. "Genetic and pharmacological approaches to study the role of the polyolpathway enzymes in diabetic and ischemic retinopathy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39558617.

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24

Cenni, Bruno. "Pharmacological aspects of malaria chemotherapy : interactions of the antimalarial drug halofantrine with human blood cells, serum proteins and Plasmodium falciparum parasitised red blood cells /." [S.l. : s.n.], 1994. http://www.gbv.de/dms/bs/toc/159397723.pdf.

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25

Gabriel, Thomas [Verfasser], Onur [Gutachter] Güntürkün, and Daniel [Gutachter] Durstewitz. "Pharmacological induced activity in a rat prefrontal cortex preparation : dynamical aspects and implications for neuronal information processing / Thomas Gabriel ; Gutachter: Onur Güntürkün, Daniel Durstewitz ; Fakultät für Psychologie." Bochum : Ruhr-Universität Bochum, 2011. http://d-nb.info/1211174166/34.

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26

Klaassen, Nicolene. "Aspects of the usage of gastro–intestinal medication in South Africa : a geographical approach / N. Klaassen." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4860.

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One of the aims included in the United Nations Millennium Development Goals is to decrease the number of the world’s population without access to sanitation and water that is safe, by half by the year 2015. The use of water that is not safe for consumption leads to water–related diseases. For the purpose of this study gastro–intestinal disease was redefined as diseases of the gastro–intestinal tract caused by pathogens that spread via contaminated drinking water, poor sanitation and inadequate hygiene. Information obtained regarding the use of gastro–intestinal disease medication, may provide

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27

Bossaer, John B., and Christian M. Thomas. "Adjuvant Treatment of Newly Diagnosed Breast Cancer." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/2313.

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28

Orwig, Susan D. "Biophysical and structural characterization of proteins implicated in glaucoma and Gaucher disease." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/45816.

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The inherited form of primary open angle glaucoma, a disorder characterized by increased intraocular pressure and retina degeneration, is linked to mutations in the olfactomedin (OLF) domain of the myocilin gene. Disease-causing myocilin variants accumulate within trabecular meshwork cells instead of being secreted to the trabecular extracellular matrix thought to regulate aqueous humor flow and control intraocular pressure. Like other diseases of protein misfolding, we hypothesize myocilin toxicity originates from defects in protein biophysical properties. In this thesis, the first preparativ

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29

Kamatou, Guy Paulin Poungoue. "Indigenous Salvia species : an investigation of their pharmacological activities and phytochemistry." Thesis, 2008. http://hdl.handle.net/10539/5692.

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The genus Salvia belongs to the family Lamiaceae and encompasses 900 species worldwide of which 26 are found in southern Africa and many of them are used in local traditional medicine. However, the phytochemistry and pharmacological activities of the South African species have not been extensively investigated. The leaf trichome morphology that may be used to distinguish species was investigated with the scanning electron and light microscopy. Both glandular (capitate or peltate) and non-glandular trichomes were identified in all species. The essential oils were isolated by hydro-distil

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