Academic literature on the topic 'Phytophenoles'

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Journal articles on the topic "Phytophenoles"

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Roubicek, Cierra, Raghavendra G. Amachawadi, T. G. Nagaraja, Yonghui Li, Jinrong Wang, and Harith M. Salih. "48 Evaluation of Antimicrobial Activities of Phytophenols Against Bacterial Pathogens That Cause Liver Abscesses in Feedlot Cattle." Journal of Animal Science 99, Supplement_1 (2021): 151. http://dx.doi.org/10.1093/jas/skab054.258.

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Abstract Liver abscesses occur in finishing cattle fed high-grain, low-roughage diets. Cattle with abscessed livers do not show any clinical signs and are detected only at slaughter. Liver abscesses, which account for 67% of all liver abnormalities in cattle slaughtered in the United States, are of major economic concern to the beef industry. Fusobacterium necrophorum, Trueperella pyogenes, and Salmonella enterica, particularly the serotype Lubbock, are the main etiologic agents. Currently, the control of liver abscesses is based on in-feed use of antibiotics. The emergence and dissemination of antimicrobial resistance to antibiotics use in animals is a public health concern. Plant-based phenolic compounds, called phytophenols, are known to have antimicrobial properties. Our objectives were to evaluate antimicrobial activities of phytophenols on the liver abscess bacterial pathogens. Phytophenols extracted from rosemary, green tea, grapeseed, organic goji berry, and green coffee were selected for testing. The phytophenols were extracted using 75% aqueous acetone and total phenolic content was determined by a spectrophotometric analysis. Bacteria were cultured in Mueller-Hinton broth (S. Lubbock and T. pyogenes) or anaerobic brain-heart infusion broth (F. necrophorum with and without phytophenols, at 6, 12, 24, and 48 hours and bacterial concentrations were determined. If phytophenol was inhibitory, a micro-broth dilution method was used to quantify the inhibition. Phytophenols from green tea, grape seed, and rosemary inhibited T. pyogenes. Further studies are ongoing to investigate different concentrations of phenolic compounds on the pathogens. Phytophenols that inhibit the pathogens may have the potential to be used as feed additives to prevent liver abscesses.
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Ghazi, Al-Karaki, and Altuntas Ozlem. "Growth, mineral content and antioxidant activity of romaine lettuce in relation to development stage in soilless system." International Journal of Agricultural Sciences and Technology 1, no. 3 (2021): 27–31. https://doi.org/10.51483/IJAGST.1.3.2021.27-31.

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Lettuce is an important vegetable crop worldwide that widely grown hydroponically and usually consumed raw as salad. Developing an optimal harvest strategy could increase lettuce production and nutritional quality. The aim of the present research was to evaluate growth, mineral content, total phenols and flavonoids content and antioxidant activity of soilless (hydroponic) grown romaine lettuce (<em>Lactuca sativa</em> L. var. longifolia) leaves at three growth stages (&ldquo;S1&rdquo;-28 days after planting (DAP), &ldquo;S2&rdquo;-42 DAP, &ldquo;S3&rdquo;-56 DAP). Head fresh weight and number of leaves per head were higher at third growth stage; however, at this stage the size of lettuce head and leaf tissue hydration is highest which might affect the consumer choice for the produce. Regarding leaf chemical composition, the highest content of total phenols, flavonoids and antioxidant activity were observed during the first two growth stages. Mineral content of leaves generally decreased during plant development with significant highest contents being observed during the first growth stage for N and during the first two growth stages for P, K, Ca and Mg. In conclusion, the results of this study indicate that chemical composition of lettuce is highly dependent on plant development stage, and harvest stage might be considering for product biomass and bioactivity content to attain consumer&rsquo;s acceptance.
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Chen, Ban, Xican Li, Xiaojian Ouyang, Jie Liu, Yangping Liu, and Dongfeng Chen. "Comparison of Ferroptosis-Inhibitory Mechanisms between Ferrostatin-1 and Dietary Stilbenes (Piceatannol and Astringin)." Molecules 26, no. 4 (2021): 1092. http://dx.doi.org/10.3390/molecules26041092.

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Synthetic arylamines and dietary phytophenolics could inhibit ferroptosis, a recently discovered regulated cell death process. However, no study indicates whether their inhibitory mechanisms are inherently different. Herein, the ferroptosis-inhibitory mechanisms of selected ferrostatin-1 (Fer-1) and two dietary stilbenes (piceatannol and astringin) were compared. Cellular assays suggested that the ferroptosis-inhibitory and electron-transfer potential levels decreased as follows: Fer-1 &gt;&gt; piceatannol &gt; astringin; however, the hydrogen-donating potential had an order different from that observed by the antioxidant experiments and quantum chemistry calculations. Quantum calculations suggested that Fer-1 has a much lower ionization potential than the two stilbenes, and the aromatic N-atoms were surrounded by the largest electron clouds. By comparison, the C4′O-H groups in the two stilbenes exhibited the lowest bond disassociation enthalpies. Finally, the three were found to produce corresponding dimer peaks through ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry analysis. In conclusion, Fer-1 mainly depends on the electron transfer of aromatic N-atoms to construct a redox recycle. However, piceatannol and astringin preferentially donate hydrogen atoms at the 4′-OH position to mediate the conventional antioxidant mechanism that inhibits ferroptosis, and to ultimately form dimers. These results suggest that dietary phytophenols may be safer ferroptosis inhibitors for balancing normal and ferroptotic cells than arylamines with high electron-transfer potential.
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Liu, Qianru, Xican Li, Xiaojian Ouyang, and Dongfeng Chen. "Dual Effect of Glucuronidation of a Pyrogallol-type Phytophenol Antioxidant: A Comparison between Scutellarein and Scutellarin." Molecules 23, no. 12 (2018): 3225. http://dx.doi.org/10.3390/molecules23123225.

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To explore whether and how glucuronidation affects pyrogallol-type phytophenols, scutellarein and scutellarin (scutellarein-7-O-glucuronide) were comparatively investigated using a set of antioxidant analyses, including spectrophotometric analysis, UV-vis spectra analysis, and ultra-performance liquid chromatography coupled with electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (UPLC-ESI-Q-TOF-MS/MS) analysis. In spectrophotometric analyses of the scavenging of 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+•), and 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide radicals (PTIO•) and the reduction of Cu2+ ions, scutellarein showed lower IC50 values than scutellarin. However, in •O2−-scavenging spectrophotometric analysis, scutellarein showed higher IC50 value than scutellarin. The analysis of UV-Vis spectra obtained after the Fe2+-chelating reaction of scutellarin showed a typical UV-Vis peak (λmax = 611 nm), while scutellarein showed no typical peak. In UPLC-ESI-Q-TOF-MS/MS analysis, mixing of scutellarein with DPPH• yielded MS peaks (m/z 678, 632, 615, 450, 420, 381, 329, 300, 288, 227, 196, 182, 161, and 117) corresponding to the scutellarein-DPPH adduct and an MS peak (m/z 570) corresponding to the scutellarein-scutellarein dimer. Scutellarin, however, generated no MS peak. On the basis of these findings, it can be concluded that glucuronidation of pyrogallol-type phytophenol antioxidants has a dual effect. On the one hand, glucuronidation can decrease the antioxidant potentials (except for •O2− scavenging) and further lower the possibility of radical adduct formation (RAF), while on the other hand, it can enhance the •O2−-scavenging and Fe2+-chelating potentials.
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Jayaraj, Premkumar, Chandrakala A. Narasimhulu, Sanjay Rajagopalan, Sampath Parthasarathy, and Rajagopal Desikan. "Sesamol: a powerful functional food ingredient from sesame oil for cardioprotection." Food & Function 11, no. 2 (2020): 1198–210. http://dx.doi.org/10.1039/c9fo01873e.

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Zhang, Wenhui, Xican Li, Yujie Hua, et al. "Antioxidant product analysis of Hulu Tea (Tadehagi triquetrum)." New Journal of Chemistry 45, no. 43 (2021): 20257–65. http://dx.doi.org/10.1039/d1nj02639a.

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Shi, Yimin, Side Yao, Zhongjian Jia, Nianyun Lin, and Rongliang Zheng. "Dietary phytophenols act as scavengers of reducing radicals." Food Chemistry 124, no. 4 (2011): 1322–27. http://dx.doi.org/10.1016/j.foodchem.2010.07.075.

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Divisha, R., V. Ranganathan, K. Vijayakaran, A. Elamaran, and Senthil Kumar P. "Quantifying phytophenols in Andrographis paniculata and Withania somnifera leaf extracts." Journal of Phytopharmacology 7, no. 6 (2018): 477–79. http://dx.doi.org/10.31254/phyto.2018.7604.

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Andrographis paniculata (Nilavembu) and Withania somnifera (Ashwagandha) are some of the commonly available herbs, used for treating a wide range of ailments in man and animals. Both the plants possesses a wide spectrum of pharmacological effects attributed to their various active phytochemical constituents. The present study was undertaken to assess the qualitative phytochemistry and to estimate the total phenolic content of leaf extracts of the two plants by Spectrophotometry and Thin Layer Chromatography. The results thus obtained suggest that the leaves of Andrographis paniculata and Withania somnifera are potential sources of healthy phytochemicals especially phenols
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Shah, Kamal, and Gaurav Krishna. "Chemical Characterization and Pharmacological Evaluation of Phytophenols-Etodolac Mutual Prodrugs." Iraqi Journal of Pharmaceutical Sciences( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 32, no. 3 (2023): 49–59. http://dx.doi.org/10.31351/vol32iss3pp49-59.

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Etodolac is choice of drug for pain and inflammation but has major side effects of gastric ulcers that are due to free carboxylic group. Etodolac belongs to the chemical class of non-selective COX-inhibitor but preferentially COX-2 inhibitor. Here the ester linked mutual prodrugs of etodolac with phytophenols like vanillin, carvacrol, umbelliferone, guaiacol, sesamol and syringaldehyde were synthesized. All the prodrugs were characterized by IR-spectroscopy, 1H-NMR, 13C-NMR and mass spectrometry. Among the synthesized prodrugs, the Eto-van, Eto-umbe, Eto-sesa and Eto-syr showed improved analgesic and anti-inflammatory activity compared to etodolac. All the synthesized prodrugs showed less ulcerogenic side effects compared to etodolac.
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Montagu, Angelique, Patrick Saulnier, Elisabeth Rossines, and Marie-Laure Joly Guillou. "Prevention of Bacterial Infections Using Encapsulated Phytophenolic Actives." Journal of Nanopharmaceutics and Drug Delivery 2, no. 1 (2014): 1–16. http://dx.doi.org/10.1166/jnd.2014.1036.

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Dissertations / Theses on the topic "Phytophenoles"

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Kaniewska, Joanna J. "Effect of increased fruit and vegetable intake on phytophenolic levels in humans and the impact on antioxidant capacity, DNA damage and protein expression." Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=225810.

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Montagu, Angélique. "Composants aromatiques nano-encapsulés : une alternative face à la résistance aux antibiotiques : Démonstration des effets biologiques seuls ou nano-encapsulés de l’in vitro à l’in vivo Prevention of Bacterial Infections Using Encapsulated Phytophenolic Actives Aromatic and terpenic compounds loaded in lipidic nanocapsules: activity against multi-drug resisant Acinobacter baumannii assessed in vitro and in a murine model of sepsis Demonstration of the interactions between aromatic compound-loaded lipid nanocapsules and Acinetobacter baumannii bacterial membrane." Thesis, Angers, 2016. http://www.theses.fr/2016ANGE0072.

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Face à la montée en puissance des bactéries multi-résistantes, la découverte de nouvelles stratégies antibactériennes s’impose. Une alternative est l’utilisation de substances actives antibactériennes issues d’huiles essentielles. Ces actifs de nature lipophile, ont été encapsulés via les nanocapsules lipidiques (NCL) pour une utilisation par voie systémique. L’efficacité de ces NCL chargées en actifs a été montrée dans un modèle de sepsis à Acinetobacter baumannii avec un taux de survie de 45% à 55%. Notre étude a montré le pouvoir d’attraction et de pénétration du carvacrol (Car) encapsulé via les fonctions hydroxyles vis-à-vis de la membrane bactérienne. Les effets biologiques de ces actifs ont été caractérisés par une dégradation de l’ARNr et une surexpression des gènes codant pour des heat shock protein. Une surexpression de la catalase due au Car est également observée, en lien avec le stress oxydatif (rôle de détoxification). Nos travaux ont montré que les bactéries pourraient utiliser dans ce processus une stratégie de défense contre le Car en utilisant les ROS endogènes lors d’une réponse au stress environnemental. Ces effets biologiques sont conservés après l’encapsulation des actifs par les NCL. Dans un modèle in vivo de pneumopathie, aucune survie animale n’a été constatée, malgré la post-insertion des NCL, qui est censée augmenter leur furtivité dans le sang. L’infection pulmonaire n’a pas favorisé d’accumulation des NCL dans les poumons. Ce phénomène pourrait s’expliquer par la métabolisation du Cin en acide cinnamique dans le sang, forme oxydée de l’actif qui réduirait drastiquement l’activité antibactérienne des NCL chargées en Car-Cin<br>Faced with the rise of multidrug-resistant bacteria, the discovery of new antibacterial strategies is imperative. An alternative is the use of antibacterial active substances from essential oils. These lipophilic compounds were encapsulated via lipidic nanocapsules(LNC) allowing a use by systemic way. The efficacy of actives loaded LNC has been showed in a murine model of sepsis against Acinetobacter baumannii with a survival rate of 45% to 55%. Our study showed the power of attraction and penetration of the encapsulated carvacrol (Car) via the hydroxyl functions. The biological effects of these compounds were characterized by a degradation of rRNA, an over expression of genes encoding heat shock proteins. A catalase overexpression was also observed which is related to an oxidative stress (role of detoxification). Our works showed that bacteria could use in this process, a defense strategy against Car using the endogenous reactive oxygen species in response to environmental stress. These biological effects are preserved after encapsulation by LNC. In an in vivo model of pneumonia, no animal survival has been observed, despite the use of pegylated LNC, which is supposed to increase their stealth in the blood. Pulmonary infection did not promote the LNC accumulation in the lungs. This phenomenon could be explained by the metabolization of Cin in cinnamic acid in the blood, the oxidized form ofthe compound which would drastically reduce the antibacterial activity of Car-Cin loaded LNC
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Book chapters on the topic "Phytophenoles"

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Hoda, Muddasarul, Shanmugam Hemaiswarya, and Mukesh Doble. "Synergistic Behavior of Phytophenolics with Antidiabetic Drugs." In Role of Phenolic Phytochemicals in Diabetes Management. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-8997-9_5.

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Bahorun, Theeshan, Deena Ramful-Baboolall, Vidushi Neergheen-Bhujun, et al. "Phytophenolic Nutrients in Citrus: Biochemical and Molecular Evidence." In Advances in Citrus Nutrition. Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-4171-3_3.

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Kling, Danielle N., Guillermo E. Marcial, Dana N. Roberson, Graciela L. Lorca, and Claudio F. Gonzalez. "The Synergistic Contribution of Lactobacillus and Dietary Phytophenols in Host Health." In Probiotics and Prebiotics in Human Nutrition and Health. InTech, 2016. http://dx.doi.org/10.5772/63787.

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Bahorun, Theeshan, Vidushi Neergheen-Bhujun, Naushad A. Toolsee, Jhoti Somanah, Amitabye Luximon-Ramma, and Okezie I. Aruoma. "Bioactive Phytophenolics and Antioxidant Functions of Aqueous and Organic Tea Extracts." In Tea in Health and Disease Prevention. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-384937-3.00030-6.

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