Academic literature on the topic 'Phytosomes'

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Journal articles on the topic "Phytosomes"

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JAIN, ARIHANT, RICHA VERMA, and PARULBEN D. MEHTA. "FORMULATION AND EVALUATION OF PHYTOSOMES LOADED WITH PITHECELLOBIUM BIJENINUM LEAF EXTRACT." Current Research in Pharmaceutical Sciences 13, no. 3 (2023): 151–56. http://dx.doi.org/10.24092/crps.2023.130306.

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The objective of the present study was to prepare phytosomal formulation loaded with aqueous extract of Pithecellobium bijeninum leaves. The extraction of leaf powder was done by maceration technique using 90:10 ethanol-water mixture with an extraction yield of 6.12%. The extract was found to contain alkaloids, and flavonoids and the total phenolic content was found to be 23.2 ± 0.827 %w/w. Phytosomes of the extract were prepared by solvent evaporation method using lecithin as the lipid molecule. The particle size of the phytosomes was from 468 nm to 1827 nm in size with a polydispersity index
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Mavi, Nitin, Pankaj Kumar Sharma, and Dilip Kumar Gupta. "Phytosomes: Bridging Nature And Nanotechnology For Enhanced Drug Delivery." International Journal of Environmental Sciences 11, no. 8s (2025): 801–18. https://doi.org/10.64252/qj5e5a23.

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The development of phytosomal drug delivery systems represents a significant advancement in natural medicine, addressing longstanding challenges associated with botanical compounds, including poor absorption and permeation rates, as well as limited bioavailability. The molecular interaction between phytoconstituents and phospholipids, particularly phosphatidylcholine, results in the formation of phytosomes, which substantially improve the lipophilicity and absorption characteristics of hydrophilic extracts. This phytosomal system provides two primary advantages through its pharmaco-absorptive
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Kumar, Arun, Bimlesh Kumar, Sachin Kumar Singh, Barinder Kaur, and Saurabh Singh. "A REVIEW ON PHYTOSOMES: NOVEL APPROACH FOR HERBAL PHYTOCHEMICALS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 10 (2017): 41. http://dx.doi.org/10.22159/ajpcr.2017.v10i10.20424.

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The poor oral bioavailability of polyphenolic compound can be enhanced through the incorporation of them into phospholipid based self-assembled delivery system, i.e. popularly known as phytosome. “Phyto” means plants and “some” resembles a covering around/or a structure. Phytosome is generally prepared by reacting one or two moles of polyphenolic phytoconstituents and phospholipid. It may be either in the ratio of 1:1 and 1:2. By using phytosomes, one can also achieve enhanced rate and extent of the passage of lipophilic herbal constituents across lipid membrane that explains its character as
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Alhakamy, Nabil A., Shaimaa M. Badr-Eldin, Usama A. Fahmy, et al. "Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells." Pharmaceutics 12, no. 8 (2020): 761. http://dx.doi.org/10.3390/pharmaceutics12080761.

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Thymoquinone (TQ), a natural polyphenol, has been associated with various pharmacological responses; however, low bioavailability of TQ limits its clinical application. Thus, a novel phytosomal delivery system of TQ-Phospholipon® 90H complex (TQ-phytosome) was developed by refluxing combined with anti-solvent precipitation. This TQ delivery system was optimized by a three-factor, three-level Box-Behnken design. The optimized TQ-phytosome size was (45.59 ± 1.82 nm) and the vesicle size was confirmed by transmission electron microscopy. The in vitro release pattern of the formulation indicated a
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Pawar, Harshal A., and Bhagyashree D. Bhangale. "Development and Evaluation of Sustained Release Lipid Nanocarriers for Curcumin." Current Nanomaterials 5, no. 3 (2020): 224–35. http://dx.doi.org/10.2174/2405461505999200917122147.

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Background: Lipid based excipients have increased acceptance nowadays in the development of novel drug delivery systems in order to improve their pharmacokinetic profiles. Drugs encapsulated in lipids have enhanced stability due to the protection they experience in the lipid core of these nano-formulations. Phytosomes are newly discovered drug delivery systems and novel botanical formulation to produce lipophilic molecular complex which imparts stability, increases absorption and bioavailability of phytoconstituent. Curcumin, obtained from turmeric (Curcuma longa), has a wide range of biologic
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Tiwari, Gaurav, Desu Brahma Srinivasa Rao, Gurinderdeep Singh, and NG Raghavendra Rao. "Development and Assessment of Phytosomes for the Treatment of Polycystic Ovarian Syndrome." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 02 (2024): 660–63. http://dx.doi.org/10.25258/ijddt.14.2.07.

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Phytosomes, a novel drug delivery system, have gained attention for their potential in the treatment of polycystic ovarian syndrome (PCOS). Polycystic ovaries, unpredictable menstrual cycles, and hormonal imbalances are the hallmarks of PCOS, a frequent endocrine disorder affecting women of reproductive age. The main aim is to prepare and evaluate phytosomes for the treatment of PCOS. The materials used were guggul from Commiphora mukul, berberine from Berberis vulgaris and green tea from Camellia sinensis. All the phytosomal formulations are prepared in ratios and further evaluated. Phytosoma
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Tiwari, Gaurav, Desu Brahma Srinivasa Rao, Gurinderdeep Singh, and N. G. Raghavendra Rao. "Development and Assessment of Phytosomes for the Treatment of Polycystic Ovarian Syndrome." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 15, no. 02 (2024): 845–48. http://dx.doi.org/10.25258/ijpqa.15.2.47.

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Phytosomes, a novel drug delivery system, have gained attention for their potential in the treatment of polycystic ovarian syndrome (PCOS). Polycystic ovaries, unpredictable menstrual cycles, and hormonal imbalances are the hallmarks of PCOS, a frequent endocrine disorder affecting women of reproductive age. The main aim is to prepare and evaluate phytosomes for the treatment of PCOS. The materials used were Guggul from Commiphora mukul, berberine from Berberis vulgaris and green tea from Camellia sinensis. All the phytosomal formulations are prepared in ratios and further evaluated. Phytosoma
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Kaur, Baljeet, Anamika Saxena, Kirti Roy, Manoj Bhardwaj, and Manoj Bisht. "DEVELOPMENT AND IN-VITRO EVALUATION OF PHYTOSOMES CONTAINING HERBAL EXTRACT OF CENTELLA ASIATICA FOR ANTIULCER AND ANTIOXIDANT ACTIVITY." Journal of Advanced Scientific Research 14, no. 03 (2023): 29–44. http://dx.doi.org/10.55218/jasr.2023140305.

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Herbal medications have a diverse range of active constituents allowing us to use them in a variety of ways, but active constituents are poorly absorbed due to their strong polarity and low lipophilicity, resulting in low bioavailability. The aim of this research was to improve bioavailability by development and in-vitro evaluation of phytosomes containing herbal extract of Centella asiatica for its antioxidant and gastroprotective activity. Phytosomes of Centella asiatica were prepared by reflex method and further it is characterized and evaluated. The complex formation was estimated by FTIR
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Alhakamy, Nabil A., Usama A. Fahmy, Shaimaa M. Badr-Eldin, et al. "Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells." Pharmaceutics 12, no. 4 (2020): 346. http://dx.doi.org/10.3390/pharmaceutics12040346.

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Icariin (ICA) is a flavonol glycoside that has pleiotropic pharmacological actions. It has cytotoxic effects against ovarian cancer cells and increases their chemosensitivity to chemotherapeutic drugs. Phytosomes are identified for their potential in drug delivery of cytotoxic agents. Thus, the purpose of this study was to determine the potential enhancement of ICA cytotoxicity activity in OVCAR-3 ovarian cancer cells via its formulation in phytosomes. ICA-phytosomal formulation was optimized using a Box–Behnken design. Particle size, shape, and in vitro drug release were used to characterize
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Sonali, Balasaheb Pawar *. Abdul Wahid Ambekar Satyam Chemate. "FORMULATION AND CHARACTERIZATIONS OF AN HERBAL ANTI - INFLAMMATORY PHYTOSOME OF GINGER EXTRACT." Journal of Pharma Research 7, no. 7 (2018): 167–70. https://doi.org/10.5281/zenodo.1322958.

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<strong><em>ABSTRACT</em></strong> <strong><em>P</em></strong><em>hytosomes are introduced advanced microsphere or cell forms of herbal products. These are the lipid vesicles in which large variety of phytochemicals can be incorporated. These are the lipid compatible molecular complex. Phytosome is a novel approach of herbal drug delivery, are superior in comparison to liposome and other conventional drug delivery system. Phytosomes are better absorbed than liposome and showing better bioavailability. Phytosomes are lipid compatible molecular complex and it has been found in various skin care
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Dissertations / Theses on the topic "Phytosomes"

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Bepe, Nyashadzashe. "Preparation, characterisation and evaluation of Artemisia afra phytosomes with modified release properties." University of the Western Cape, 2017. http://hdl.handle.net/11394/6083.

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Magister Pharmaceuticae - Mpharm<br>Dissolution studies on various dosage forms (powder, tablets, teabags and alginate beads) of the Artemisia afra freeze dried aqueous extract (FDAE) all exhibit a rapid release profile. Generally, such a release profile may be therapeutically undesirable as it may affect absorption and hence the therapeutic outcome. In addition, also associated with rapid release profiles, is frequent dosing required (to maintain therapeutic plasma concentrations) and unavoidable fluctuations in plasma drug concentrations, leading to under and or over dosing. Based on the afo
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Daghman, Mohamed Ibrahim. "Comparison of the physicochemical characteristics and flavonoid release profiles of Sutherlandia frutescens phytosomes versus liposomes." University of the Western Cape, 2016. http://hdl.handle.net/11394/5055.

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Magister Pharmaceuticae - MPharm<br>Sutherlandia frutescens is a traditional plant medicine widely used in South Africa. Traditionally, the leaves of S. frutescens are mainly used as a tea, but these traditional dosage forms have several disadvantages, including that they are not particularly convenient to prepare and store, encourage dosage inaccuracy and are highly susceptible to microbial contamination. To solve these problems, dried aqueous extract forms, e.g. freeze dried aqueous extract (FDAE) of S. frutescens were prepared, but they, in turn, may still suffer from instability
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Book chapters on the topic "Phytosomes"

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Tahir, Uzma, and Mohammad Rafiq Khan. "Cardamom-Based Phytosomes." In Cardamom (Elettaria cardamomum): Production, Processing and Properties. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-35426-7_16.

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Saleemi, Mansab Ali, and Vuanghao Lim. "Phytosomes Used for Herbal Drug Delivery." In Nanotechnology in the Life Sciences. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-12658-1_9.

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Kaur, Palakdeep, and Uttam Kumar Mandal. "Phytosomes: Preparations, Characterization, and Future Uses." In Medicinal Plants. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003277408-13.

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Telange, Darshan R., Shirish P. Jain, Anil M. Pethe, and Vivek S. Dave. "Phytosomes and Phytosomal Nanoparticles: A Promising Drug Delivery System for Flavonoids and Nutraceuticals." In Nutraceutical Delivery Systems. Apple Academic Press, 2022. http://dx.doi.org/10.1201/9781003189671-9.

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Güngör, Sevgi, Özlem Akbal-Dağıstan, Evren Algın Yapar, Murat Kartal, and Yıldız Özsoy. "Phytosomes as Novel Carriers of Herbal Extracts." In Novel Drug Delivery Systems for Phytoconstituents. CRC Press, 2019. http://dx.doi.org/10.1201/9781351057639-4.

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Purkayastha, Jubilee, and Jayita Ghosh. "Phytosomes: The Novel Drug Delivery System for Phytomedicine." In New Age Herbals. Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8291-7_21.

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Kumar, Dinesh, Nitin Vats, Kamal Saroha, and Avtar Chand Rana. "Phytosomes as Emerging Nanotechnology for Herbal Drug Delivery." In Sustainable Agriculture Reviews. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41838-0_7.

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Sumant, Subh Naman, and Ashish Baldi. "Quality-by-Design Perspectives of Phytosomes for Pharmaceutical Benefits." In Advances in Novel Phytopharmaceuticals. CRC Press, 2024. http://dx.doi.org/10.1201/9781003300588-10.

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Froiio, Francesca, Agnese Gagliardi, Massimo Fresta, Donato Cosco, and Donatella Paolino. "Phytosomes as Useful Drug Delivery Systems for Cosmeceutical Application." In Novel Drug Delivery Systems for Phytoconstituents. CRC Press, 2019. http://dx.doi.org/10.1201/9781351057639-6.

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Hatamipour, Mahdi, Tannaz Jamialahmadi, Mahin Ramezani, et al. "Protective Effects of Curcumin Phytosomes Against High-Fat Diet-Induced Atherosclerosis." In Pharmacological Properties of Plant-Derived Natural Products and Implications for Human Health. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-64872-5_4.

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Conference papers on the topic "Phytosomes"

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Joshi, Mamta, Amrita Pargaien, Sunita Waila Tiwari, Garima Chand, Neha Joshi, and Heena. "Phytosomes: The Inventive and Futuristic Technology for Boosting the Bioavailability of Botanicals and Nutraceuticals Through Artificial Intelligence." In 2024 International Conference on Intelligent Systems and Advanced Applications (ICISAA). IEEE, 2024. https://doi.org/10.1109/icisaa62385.2024.10829205.

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Costa, Micaela, Cristina Soares, Aurora Silva, Clara Grosso, and Cristina Delerue-Matos. "Characterization of Codium tomentosum Phytosomes and Their Neuroprotective Potential." In Foods 2022. MDPI, 2022. http://dx.doi.org/10.3390/foods2022-13009.

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Portela, Mariana, Aurora Silva, Maria Carpena, et al. "Phytosomes-Based Nanocarriers Enhanced with Seaweed Extracts: Overcoming the Blood–Brain Barrier." In ASEC 2024. MDPI, 2025. https://doi.org/10.3390/engproc2025087075.

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O.I., Vasiliadi, Kuzminova E.V., and Dolgov E.P. "STUDYING THE PHARMACOLOGICAL PROPERTIES OF A HEPATOPROTECTIVE DRUG DURING EXPERIMENTAL AMMONIA INTOXICATION OF BROILER CHICKENS." In OF THE ANNIVERSARY Х INTERNATIONAL SCIENTIFIC AND PRACTICAL CONFERENCE «INNOVATIVE TECHNOLOGIES IN SCIENCE AND EDUCATION» («ITSE 2022» CONFERENCE). DSTU-Print, 2022. http://dx.doi.org/10.23947/itse.2022.33-36.

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The article presents the results of the study of the pharmacological efficiency of the hepatoprotective drug phytosomin in experimental ammonia intoxication of broiler chickens. The conducted studies have determined that phytosomin contributes to an increase in body weight gain in poultry, and its preventive use allows to increase the period of manifestation of clinical signs of ammonia intoxication and their severity, to reduce pathological changes in the organs of the respiratory and circulatory systems.
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Dewi, Nur Aini, Ganet Eko, and Muhamad Dzakwan. "Development of the Myricetin Nano-Phytosome Formula with Phosphatidylcholine Variations." In 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019). Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.200523.066.

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Muley, Mrunal, and Manjusha Bhange. "An overview of phytosome as an innovative drug delivery system." In INTERNATIONAL CONFERENCE ON INTELLIGENT TECHNOLOGIES FOR SUSTAINABLE ENERGY MANAGEMENT AND CONTROL 2023: ITSEMC2023. AIP Publishing, 2024. https://doi.org/10.1063/5.0240458.

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Saputra, Yuli Edy, Muhammad Dzakwan, and Nur Aini Dewi. "Evaluation Nano-Phytosome of Myricetin with Thin Layer Film Hydration-Sonication Method." In 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019). Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.200523.070.

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Al-Yasari, Ali Mosa Rashid, Mohammed A. Aboktifa, Zainab Abdulkaleq Ahmed, Hadeel S. Almaliki, Ruqaya K. Abbas, and Adnan Mansour Jasim. "The physiological role of phytosomal curcumin to mitigate hemolytic anemia and cytogenic effect induced by phenylhydrazine in rats." In TRANSPORT, ECOLOGY, SUSTAINABLE DEVELOPMENT: EKO VARNA 2023. AIP Publishing, 2024. http://dx.doi.org/10.1063/5.0191865.

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PAIVA, RAFAEL DA SILVA, ALINE MEDEIROS LIMA, ADRYANA TRABASSOS DOS SANTOS, and ELIZA DE JESUS BARROS DOS SANTOS. "IDENTIFICAÇÃO E CARACTERIZAÇÃO GENÔMICA DE GENES DA GLUTATIONA PEROXIDASE EM (MANIHOT ESCULENTA) CRANTZ." In III Congresso Brasileiro de Ciências Biologicas. Revista Multidisciplinar de Educação e Meio Ambiente, 2022. http://dx.doi.org/10.51189/iii-conbracib/6187.

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Introdução: A mandioca (Manihot esculenta Crantz) é cultivada em inúmeros países apresentando grande importância socioeconômica, no entanto, a sua produção pode sofrer prejuízos econômicos quando a planta está exposta a patógenos. Nesse contexto, os vegetais em resposta ao estresse biótico recorrem a genes envolvidos a tais sinais, como o gene da peroxidase (POD) que constitui uma classe de enzimas oxidoredutases que possui a função de catalisar a oxidação do substrato utilizando o poder oxidante do peroxido de hidrogênio. Objetivo: Portanto, este estudo tem como objetivo identificar e caracte
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