Log in

Relevant bibliographies by topics / PIAS / Journal articles

To see the other types of publications on this topic, follow the link: PIAS.

Journal articles on the topic 'PIAS'

Author: Grafiati

Published: 4 June 2021

Last updated: 13 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'PIAS.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Kotaja, Noora, Saara Aittomäki, Olli Silvennoinen, Jorma J. Palvimo, and Olli A. Jänne. "ARIP3 (Androgen Receptor-Interacting Protein 3) and Other PIAS (Protein Inhibitor of Activated STAT) Proteins Differ in Their Ability to Modulate Steroid Receptor-Dependent Transcriptional Activation." Molecular Endocrinology 14, no. 12 (2000): 1986–2000. http://dx.doi.org/10.1210/mend.14.12.0569.

Full text

Abstract:

Abstract Steroid receptors mediate their actions by using various coregulatory proteins. We have recently characterized ARIP3/PIASxα as an androgen receptor (AR)-interacting protein (ARIP) that belongs to the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] protein family implicated in the inhibition of cytokine signaling. We have analyzed herein the roles that four different PIAS proteins (ARIP3/PIASxα, Miz1/PIASxβ, GBP/PIAS1, and PIAS3) play in the regulation of steroid receptor- or STAT-mediated transcriptional activation. All PIAS proteins are a

APA, Harvard, Vancouver, ISO, and other styles

2

Tirard, M., J. Jasbinsek, OF Almeida, and TM Michaelidis. "The manifold actions of the protein inhibitor of activated STAT proteins on the transcriptional activity of mineralocorticoid and glucocorticoid receptors in neural cells." Journal of Molecular Endocrinology 32, no. 3 (2004): 825–41. http://dx.doi.org/10.1677/jme.0.0320825.

Full text

Abstract:

Corticosteroid actions in the brain are exerted via the mineralocorticoid receptor (MR) and glucocorticoid receptor (GR). These receptors share several structural and functional similarities but their activation in the brain triggers distinct biological actions, for instance on neuronal survival or the regulation of the hypothalamo-pituitary-adrenal axis. Like other hormone-activated receptors, the transcriptional properties of the MR and GR depend on their ability to recruit a variety of co-regulators, which modulate their activity on target promoters, in a specific manner. The N-terminal reg

APA, Harvard, Vancouver, ISO, and other styles

3

Wong, Kelly A., Rachel Kim, Heather Christofk, Jing Gao, Gregory Lawson, and Hong Wu. "Protein Inhibitor of Activated STAT Y (PIASy) and a Splice Variant Lacking Exon 6 Enhance Sumoylation but Are Not Essential for Embryogenesis and Adult Life." Molecular and Cellular Biology 24, no. 12 (2004): 5577–86. http://dx.doi.org/10.1128/mcb.24.12.5577-5586.2004.

Full text

Abstract:

ABSTRACT Protein inhibitor of activated STAT Y (PIASy) is the shortest member of the PIAS family and has been reported to modulate the transcriptional activities of STAT1, lymphoid enhancer factor 1 (LEF-1), and the androgen receptor. PIAS proteins have also been identified as E3 ligases for the small ubiquitin-like modifier (SUMO) proteins. PIASy in particular has been reported to mediate SUMO-2/3 modification of LEF-1, sequestering it into nuclear bodies, and SUMO-1 ligation to c-Myb, modulating its transcriptional activation properties. We have cloned murine Piasy and a splice variant which

APA, Harvard, Vancouver, ISO, and other styles

4

Brayman, Melissa Jo, Neeraja Dharmaraj, Errin Lagow, and Daniel D. Carson. "MUC1 Expression Is Repressed by Protein Inhibitor of Activated Signal Transducer and Activator of Transcription-y." Molecular Endocrinology 21, no. 11 (2007): 2725–37. http://dx.doi.org/10.1210/me.2006-0539.

Full text

Abstract:

Abstract Mucin 1 (MUC1) is a transmembrane glycoprotein that modulates the interaction between the embryo and the uterine epithelial cell surface. MUC1 also is a tumor marker and has been implicated in the protection of cancer cells from immune cell attack as well as in cell signaling in some tumors. We and others have shown that MUC1 expression is activated by progesterone (P), TNF-α, and interferon-γ (IFN-γ). Here we demonstrate that MUC1 expression is down-regulated by overexpression of members of the protein inhibitor of activated signal transducer and activator of transcription (PIAS) fam

APA, Harvard, Vancouver, ISO, and other styles

5

Tan, Joseph-Anthony T., Jing Song, Yuan Chen, and Linda K. Durrin. "Phosphorylation-Dependent Interaction of SATB1 and PIAS1 Directs SUMO-Regulated Caspase Cleavage of SATB1." Molecular and Cellular Biology 30, no. 11 (2010): 2823–36. http://dx.doi.org/10.1128/mcb.01603-09.

Full text

Abstract:

ABSTRACT Special AT-rich sequence-binding protein 1 (SATB1) is a tissue-restricted genome organizer that provides a key link between DNA loop organization, chromatin modification/remodeling, and transcription factor association at matrix attachment regions (MARs). The SUMO E3 ligase PIAS1 enhances SUMO conjugation to SATB1 lysine-744, and this modification regulates caspase-6 mediated cleavage of SATB1 at promyelocytic leukemia nuclear bodies (PML NBs). Since this regulated caspase cleavage occurs on only a subset of SATB1, and the products are relatively stable, proteolysis likely mediates ce

APA, Harvard, Vancouver, ISO, and other styles

6

Santti, H., L. Mikkonen, A. Anand, et al. "Disruption of the murine PIASx gene results in reduced testis weight." Journal of Molecular Endocrinology 34, no. 3 (2005): 645–54. http://dx.doi.org/10.1677/jme.1.01666.

Full text

Abstract:

PIASx belongs to the PIAS protein family, the members of which modulate activities of several transcription factors and act as E3 ligases in the sumoylation pathway. The PIASx gene is highly expressed in testis, suggesting a role in spermatogenesis. To investigate the function of PIASx in vivo, we have disrupted the PIASx gene in mice. Interestingly, the knockout mice were viable and fertile. Despite the normal fertility, the testis weight of the mutant animals was reduced and their number of apoptotic testicular cells was increased. Also, the sperm count of mutant mice tended to be reduced, b

APA, Harvard, Vancouver, ISO, and other styles

7

Conn, Kristen L., Peter Wasson, Steven McFarlane, et al. "Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response." Journal of Virology 90, no. 9 (2016): 4807–26. http://dx.doi.org/10.1128/jvi.03055-15.

Full text

Abstract:

ABSTRACTSmallubiquitin-likemodifier (SUMO) is used by the intrinsic antiviral immune response to restrict viral pathogens, such as herpes simplex virus 1 (HSV-1). Despite characterization of the host factors that rely on SUMOylation to exert their antiviral effects, the enzymes that mediate these SUMOylation events remain to be defined. We show that unconjugated SUMO levels are largely maintained throughout infection regardless of the presence of ICP0, the HSV-1 SUMO-targeted ubiquitin ligase. Moreover, in the absence of ICP0, high-molecular-weight SUMO-conjugated proteins do not accumulate if

APA, Harvard, Vancouver, ISO, and other styles

8

West, Peter W. "PIAs adorer." Manufacturing Engineer 68, no. 5 (1989): 16. http://dx.doi.org/10.1049/me:19890016.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Ungureanu, Daniela, Sari Vanhatupa, Noora Kotaja, et al. "PIAS proteins promote SUMO-1 conjugation to STAT1." Blood 102, no. 9 (2003): 3311–13. http://dx.doi.org/10.1182/blood-2002-12-3816.

Full text

Abstract:

AbstractSignal transducer and activator of transcription 1 (STAT1) is a critical mediator of interferon-γ (IFN-γ)–induced transcription that is regulated through posttranslational modifications and through transacting proteins such as protein inhibitor of activated STAT1 (PIAS1). PIAS proteins have been shown to function as E3-type small ubiquitin-like modifier (SUMO) ligases, and sumoylation has been identified as a modulatory mechanism for several transcription factors. Here we show that STAT1 is subject to SUMO-1 modification, and sumoylation occurs in vivo and in vitro at a single, evoluti

APA, Harvard, Vancouver, ISO, and other styles

10

Munarriz, Eliana, Daniela Barcaroli, Anastasis Stephanou, et al. "PIAS-1 Is a Checkpoint Regulator Which Affects Exit from G1 and G2 by Sumoylation of p73." Molecular and Cellular Biology 24, no. 24 (2004): 10593–610. http://dx.doi.org/10.1128/mcb.24.24.10593-10610.2004.

Full text

Abstract:

ABSTRACT p73 is a recently described member of the p53 family, and, like p53, it undergoes a number of posttranslational modifications. Here we show, by yeast two-hybrid screening, pull-down assays, and coimmunoprecipitation, that p73α, -β, and -γ bind to the protein inhibitor of activated STAT-1 (PIAS-1) and that this binding stabilizes p73. PIAS-1 also sumoylates p73α, although not the C-terminally truncated isoforms p73β and -γ, and this requires the RING finger domain of PIAS-1. The ΔNp73α isoform can also bind, and be sumoylated by, PIAS-1. PIAS-1-mediated sumoylation decreases p73 transc

APA, Harvard, Vancouver, ISO, and other styles

11

Kotaja, Noora, Ulla Karvonen, Olli A. Jänne, and Jorma J. Palvimo. "PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases." Molecular and Cellular Biology 22, no. 14 (2002): 5222–34. http://dx.doi.org/10.1128/mcb.22.14.5222-5234.2002.

Full text

Abstract:

ABSTRACT PIAS (protein inhibitor of activated STAT) proteins interact with and modulate the activities of various transcription factors. In this work, we demonstrate that PIAS proteins xα, xβ, 1, and 3 interact with the small ubiquitin-related modifier SUMO-1 and its E2 conjugase, Ubc9, and that PIAS proteins themselves are covalently modified by SUMO-1 (sumoylated). PIAS proteins also tether other sumoylated proteins in a noncovalent fashion. Furthermore, recombinant PIASxα enhances Ubc9-mediated sumoylation of the androgen receptor and c-Jun in vitro. Importantly, PIAS proteins differ in the

APA, Harvard, Vancouver, ISO, and other styles

12

Hsieh, Hsiang-Tsan, Chih-Hung Wang, Mei-Ling Wu, Feng-Ming Yang, Yu-Chen Tai, and Meng-Chun Hu. "PIASy inhibits LRH-1-dependent CYP11A1 expression by competing for SRC-1 binding." Biochemical Journal 419, no. 1 (2009): 201–9. http://dx.doi.org/10.1042/bj20081402.

Full text

Abstract:

The orphan nuclear receptor LRH-1 (liver receptor homologue-1; NR5A2) plays a critical role in development, bile acid synthesis and cholesterol metabolism. LRH-1 is also expressed in the ovary where it is implicated in the regulation of steroidogenic genes for steroid hormone synthesis. In the present study, we investigated the molecular mechanisms of the transcriptional regulation of CYP11A1 by LRH-1 and found that LRH-1-mediated transactivation was markedly repressed by PIASy [protein inhibitor of activated STAT (signal transducer and activator of transcription) y], the shortest member of th

APA, Harvard, Vancouver, ISO, and other styles

13

O'Shea, John J., and Wendy Watford. "A peek at PIAS." Nature Immunology 5, no. 9 (2004): 875–76. http://dx.doi.org/10.1038/ni0904-875.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Lonsdale, Tom. "AVA, ACAC and PIAS." Australian Veterinary Journal 78, no. 10 (2000): 673. http://dx.doi.org/10.1111/j.1751-0813.2000.tb10395.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Palvimo, J. J. "PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription." Biochemical Society Transactions 35, no. 6 (2007): 1405–8. http://dx.doi.org/10.1042/bst0351405.

Full text

Abstract:

Transcriptional activity of signal-dependent transcription factors, including nuclear receptors, relies on interacting co-regulator proteins, many of which possess protein-modifying activity. SUMOs (small ubiquitin-related modifiers) and their conjugation pathway components act as co-regulator proteins for numerous transcription factors that also are often targets for SUMO modification. PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] proteins promote SUMOylation in a manner that resembles the action of RING-type ubiquitin E3 ligases. PIAS proteins

APA, Harvard, Vancouver, ISO, and other styles

16

Depaux, A., F. Regnier-Ricard, A. Germani, and N. Varin-Blank. "A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation." Oncogene 26, no. 46 (2007): 6665–76. http://dx.doi.org/10.1038/sj.onc.1210486.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Iwata, Makoto, Kyohei Kanoh, Takuya Imaoka, and Kazuo Nagasawa. "Total synthesis of (+)-cylindradine A." Chem. Commun. 50, no. 53 (2014): 6991–94. http://dx.doi.org/10.1039/c4cc00137k.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Yakass, Michael B., David Franco, and Osbourne Quaye. "Yellow Fever Virus Down-Regulates mRNA Expression of SOCS1 in the Initial Phase of Infection in Human Cell Lines." Viruses 12, no. 8 (2020): 802. http://dx.doi.org/10.3390/v12080802.

Full text

Abstract:

Flaviviruses are constantly evolving diverse immune evasion strategies, and the exploitation of the functions of suppressors of cytokine signalling (SOCS) and protein inhibitors of activated STATs (PIAS) to favour virus replication has been described for Dengue and Japanese encephalitis viruses but not for yellow fever virus (YFV), which is still of global importance despite the existence of an effective vaccine. Some mechanisms that YFV employs to evade host immune defence has been reported, but the expression patterns of SOCS and PIAS in infected cells is yet to be determined. Here, we show

APA, Harvard, Vancouver, ISO, and other styles

19

Wattimena, Jessica D., and Mansye Ronal Ayal. "Analisis Perubahan Garis Pantai Desa Rutong Kota Ambon." Jurnal Teknik Sipil 14, no. 2 (2019): 115–36. http://dx.doi.org/10.28932/jts.v14i2.1796.

Full text

Abstract:

Ambon sebagai ibukota Provinsi Maluku merupakan Daerah Kepulauan yang mana sebagian besardesanya berada pada Daerah pesisir pantai. Hal ini membuat timbulnya berbagai permasalahanpantai. Pantai Desa Rutong Kecamatan Leitmur Selatan Kota Ambon merupakan salah satu daerahyang sering mendapat serangan gelombang dan mengakibatkan kerusakan yang cukup parah.Berdasarkan informasi dan tinjauan yang dilakukan, jenis pantai pada Desa Rutong ialah pantaipasir (Sandy Beach). Kondisi ini menyebabkan sejumlah besar material (Pasir) terbawa akibatgelombang angin dan pasang tertinggi sehingga terjadi erosi y

APA, Harvard, Vancouver, ISO, and other styles

20

Imaoka, Takuya, Makoto Iwata, Takafumi Akimoto, and Kazuo Nagasawa. "Synthetic Approaches to Tetracyclic Pyrrole Imidazole Marine Alkaloids." Natural Product Communications 8, no. 7 (2013): 1934578X1300800. http://dx.doi.org/10.1177/1934578x1300800722.

Full text

Abstract:

Oroidin derived pyrrole imidazole marine alkaloids (PIAs) are attractive targets for synthetic organic chemists because of their structural complexity and diversity as well as their interesting biological activities. A number of efforts have been carried out to develop strategies for the synthesis of these natural products. Members of PIAs ( eg., 2-7) which contain tetracyclic ring systems possessing characteristic cyclic guanidine or urea moieties show significant biological activities including anticancer activity and agonistic activity against the adrenoceptor. In this review investigations

APA, Harvard, Vancouver, ISO, and other styles

21

Живковић, Валентина. "ПОМЕНИ ГРОБНОГ МЕСТА У ТЕСТАМЕНТИМА КОТОРАНА (1326–1337) REFERENCES TO BURIAL PLACES IN THE TESTAMENTS OF KOTOR CITIZENS (1326–1337)". Историјски часопис, № 66/2017 (31 грудня 2017): 129–47. http://dx.doi.org/10.34298/ic1766129z.

Full text

Abstract:

Апстракт: У раду ce разматрају помени гробног места у оквиру сачуваног корпуса тестамената Которана из времена од 1326. до 1337. године. Основни задатак рада јесте утврђивање заступљености ове врсте завештања у оквиру формалне и садржајне структуре легата ad pias causas, а потом и анализа избора гробног места са становишта ширег контекста фунерарне праксе у касносредњовековном Котору. Кључне речи: тестаменти, касносредњовековни Котор, гробно местo, легати ad pias causas, катедрала Светог Трипуна, фрањевачки манастир, prandium pro anima. Abstract: The paper examines references to burial places

APA, Harvard, Vancouver, ISO, and other styles

22

Beliakoff, Jason, and Zijie Sun. "Zimp7 and Zimp10, two novel PIAS-like proteins, function as androgen receptor coregulators." Nuclear Receptor Signaling 4, no. 1 (2006): nrs.04017. http://dx.doi.org/10.1621/nrs.04017.

Full text

Abstract:

The androgen receptor (AR) plays a critical role in male sexual development and in normal and malignant prostate cell growth and survival. It has been shown that AR transcriptional activation is regulated through interactions with a variety of transcriptional co-regulators. The Protein Inhibitors of Activated STATs (PIAS) are transcriptional co-regulators, and have been shown to modulate AR-mediated transcription. In this brief, we summarize our recent studies on two novel PIAS-like proteins, Zimp7 and Zimp10. Particularly, we address the functional interactions between the AR and these two pr

APA, Harvard, Vancouver, ISO, and other styles

23

Miyauchi, Yasuhiro, Satomi Yogosawa, Reiko Honda, Tamotsu Nishida, and Hideyo Yasuda. "Sumoylation of Mdm2 by Protein Inhibitor of Activated STAT (PIAS) and RanBP2 Enzymes." Journal of Biological Chemistry 277, no. 51 (2002): 50131–36. http://dx.doi.org/10.1074/jbc.m208319200.

Full text

Abstract:

Mdm2, a ubiquitin ligase that acts on p53, is regulated by sumoylation. In the current study, we identify the enzymes responsible for the sumoylation of Mdm2. When mammalian cells are co-transfected with cDNAs encoding Mdm2 and PIAS1 or PIASxβ (proteininhibitor ofactivatedSTAT) as sumoylation enzymes, Mdm2 is highly sumoylated. Mdm2 is also sumoylated in anin vitrosystem containing PIASxβ, PIAS1, and RanBP2. When several lysine residues of Mdm2 were sequentially mutated to arginine, the K182R mutant was not sumoylated in intact cells; however, in thein vitrosystem this mutant was sumoylated by

APA, Harvard, Vancouver, ISO, and other styles

24

Haryanto, Yanuar, Iman Satyarno, and Djoko Sulistyo. "ANALISIS DAYA DUKUNG BEBAN BALOK BETON BERTULANG TAMPANG T DENGAN PERKUATAN WIRE ROPE PADA DAERAH MOMEN NEGATIF MENGGUNAKAN PROGRAM RESPONSE-2000 DAN METODE PIAS." Jurnal Teknik Sipil 13, no. 3 (2017): 173. http://dx.doi.org/10.24002/jts.v13i3.873.

Full text

Abstract:

Abstrak: Response-2000 adalah suatu program yang dapat digunakan untuk menganalisis elemen beton bertulang akibat beban aksial, momen, geser, maupun kombinasi ketiganya sehingga respon beban-lendutan dapat diprediksi dan kekuatannya dapat diketahui. Makalah ini membahas perbandingan kapasitas daya dukung beban hasil pengujian balok bertulang tampang T yang diperkuat wire rope pada daerah momen negatif dengan analisis menggunakan Response-2000 dan metode pias. Metode pias dilakukan dengan cara membagi penampang menjadi sejumlah pias dengan ketebalan tertentu, kemudian menganalisis gaya-gaya yan

APA, Harvard, Vancouver, ISO, and other styles

25

Kawata, Takefumi, Tatsunori Hirano, Shun Ogasawara, Ryota Aoshima, and Ayako Yachi. "Evidence for a functional link between Dd-STATa and Dd-PIAS, a Dictyostelium PIAS homologue." Development, Growth & Differentiation 53, no. 7 (2011): 897–909. http://dx.doi.org/10.1111/j.1440-169x.2011.01296.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Brown, James R., Kristen L. Conn, Peter Wasson, et al. "SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1." Journal of Virology 90, no. 13 (2016): 5939–52. http://dx.doi.org/10.1128/jvi.00426-16.

Full text

Abstract:

ABSTRACTAspects of intrinsic antiviral immunity are mediated bypromyelocyticleukemianuclearbody (PML-NB) constituent proteins. During herpesvirus infection, these antiviral proteins are independently recruited to nuclear domains that contain infecting viral genomes to cooperatively promote viral genome silencing. Central to the execution of this particular antiviral response is thesmallubiquitin-likemodifier (SUMO) signaling pathway. However, the participating SUMOylation enzymes are not fully characterized. We identify the SUMO ligaseproteininhibitor ofactivatedSTAT1 (PIAS1) as a constituent

APA, Harvard, Vancouver, ISO, and other styles

27

Pujiastuti, Asih. "Segmentasi Citra Kartu Pias Tipe SO-40U (1400-40S) Pada Perhitungan Lama Penyinaran Matahari." Angkasa: Jurnal Ilmiah Bidang Teknologi 9, no. 2 (2017): 9. http://dx.doi.org/10.28989/angkasa.v9i2.174.

Full text

Abstract:

The measurement of the duration of solar irradiation at the climatology station can be done using campbell stokes and pias cards. The aim of this research is to assist the climatology station operator to determine the burn object on the SO-40U (1400-40S) type of pias cards, making it easier to calculate the duration of solar irradiation. This app is designed and built to successfully segmentation the burn on the card automatically. In this research, the data was collected at a climatology station located in Barongan, Sumberagung Jetis, Bantul. Based on the test conducted segmentation generated

APA, Harvard, Vancouver, ISO, and other styles

28

PUTRI, LINDA MATARINA KARTIKA. "Peningkatan Keterampilan Membaca Nyaring Melalui Media Pias-Pias Kata pada Siswa Kelas I SDN 1 Mojorejo Ponorogo." Trapsila: Jurnal Pendidikan Dasar 1, no. 01 (2019): 81. http://dx.doi.org/10.30742/tpd.v1i01.726.

Full text

Abstract:

This classroom action research was conducted on grade 1 students of SD Negeri 1 Mojorejo Ponorogo 2014/2015 Academic Year, due to the existence of problems, namely the learning outcomes of Indonesian language subjects especially reading aloud were still low. Through word-of-mouth media this problem is tried to be improved and improved. The design of this study was to use classroom action research (PTK) methods which aimed to improve or improve the quality of continuous learning practices. The study was conducted at SD Negeri 1 Mojorejo Ponorogo and the students studied were grade 1 students to

APA, Harvard, Vancouver, ISO, and other styles

29

Martin, Nadine, Klaus Schwamborn, Henning Urlaub, Boyi Gan, Jun-Lin Guan, and Anne Dejean. "Spatial Interplay between PIASy and FIP200 in the Regulation of Signal Transduction and Transcriptional Activity." Molecular and Cellular Biology 28, no. 8 (2008): 2771–81. http://dx.doi.org/10.1128/mcb.01210-07.

Full text

Abstract:

ABSTRACT The members of the protein inhibitor of activated STAT (PIAS) family of proteins are implicated in fundamental cellular processes, including transcriptional regulation, either through action as E3 SUMO ligases or through SUMO-independent effects. We report here the identification of FIP200 (focal adhesion kinase family-interacting protein of 200 kDa) as a new PIASy-interacting protein. We show that the interaction depends on the integrity of the RING finger of PIASy and the carboxy terminus of FIP200. Both in vitro and in vivo sumoylation assays failed to reveal any sumoylation of FIP

APA, Harvard, Vancouver, ISO, and other styles

30

Fredrikzon, Johan. "Cybernetics: The Macy Conferences." Sensorium Journal 3 (March 26, 2021): 56–59. http://dx.doi.org/10.3384/sens.2002-3030.2021.3.56-59.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Sturm, Sabine, Manuel Koch та Fletcher A. White. "Cloning and Analysis of a Murine PIAS Family Member, PIASγ, in Developing Skin and Neurons". Journal of Molecular Neuroscience 14, № 1-2 (2000): 107–22. http://dx.doi.org/10.1385/jmn:14:1-2:107.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Deng, Zhiyong, Meimei Wan, and Guangchao Sui. "PIASy-Mediated Sumoylation of Yin Yang 1 Depends on Their Interaction but Not the RING Finger." Molecular and Cellular Biology 27, no. 10 (2007): 3780–92. http://dx.doi.org/10.1128/mcb.01761-06.

Full text

Abstract:

ABSTRACT As a multifunctional protein, Yin Yang 1 (YY1) has been demonstrated to regulate both gene expression and protein posttranslational modifications. However, gaps still exist in our knowledge of how YY1 can be modified and what the consequences of its modifications are. Here we report that YY1 protein can be sumoylated both in vivo and in vitro. We have identified lysine 288 as the major sumoylation site of YY1. We also discovered that PIASy, a SUMO E3 ligase, is a novel YY1-interacting protein and can stimulate the sumoylation of YY1 both in vitro and in vivo. Importantly, the effects

APA, Harvard, Vancouver, ISO, and other styles

33

Liu, Yang, Ya-Dong Zhang, Liang Guo та ін. "Protein Inhibitor of Activated STAT 1 (PIAS1) Is Identified as the SUMO E3 Ligase of CCAAT/Enhancer-Binding Protein β (C/EBPβ) during Adipogenesis". Molecular and Cellular Biology 33, № 22 (2013): 4606–17. http://dx.doi.org/10.1128/mcb.00723-13.

Full text

Abstract:

It is well recognized that PIAS1, a SUMO (small ubiquitin-like modifier) E3 ligase, modulates such cellular processes as cell proliferation, DNA damage responses, and inflammation responses. Recent studies have shown that PIAS1 also plays a part in cell differentiation. However, the role of PIAS1 in adipocyte differentiation remains unknown. CCAAT/enhancer-binding protein β (C/EBPβ), a major regulator of adipogenesis, is a target of SUMOylation, but the E3 ligase responsible for the SUMOylation of C/EBPβ has not been identified. The present study showed that PIAS1 functions as a SUMO E3 ligase

APA, Harvard, Vancouver, ISO, and other styles

34

Betz, A., N. Lampen, S. Martinek, M. W. Young, and J. E. Darnell. "A Drosophila PIAS homologue negatively regulates stat92E." Proceedings of the National Academy of Sciences 98, no. 17 (2001): 9563–68. http://dx.doi.org/10.1073/pnas.171302098.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Pechan, P. "PIAS - The Prague Institute of Advanced Studies." TATuP - Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis 5, no. 4 (1996): 50–51. http://dx.doi.org/10.14512/tatup.5.4.50.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Ghaffari, Saghi. "PIAS adds methyl-bias to HSC-differentiation." EMBO Journal 33, no. 2 (2014): 93–95. http://dx.doi.org/10.1002/embj.201387332.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Schmidt, D., and S. M�ller. "PIAS/SUMO: new partners in transcriptional regulation." Cellular and Molecular Life Sciences (CMLS) 60, no. 12 (2003): 2561–74. http://dx.doi.org/10.1007/s00018-003-3129-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Škoda, Jan. "The Prague Institute of Advanced Studies (PIAS)." Biochemical Education 19, no. 4 (1991): 203–4. http://dx.doi.org/10.1016/0307-4412(91)90102-e.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Tolkunova, Elena, Anna Malashicheva, Vladimir N. Parfenov, Claudio Sustmann, Rudolf Grosschedl, and Alexey Tomilin. "PIAS Proteins as Repressors of Oct4 Function." Journal of Molecular Biology 374, no. 5 (2007): 1200–1212. http://dx.doi.org/10.1016/j.jmb.2007.09.081.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Rytinki, Miia M., Sanna Kaikkonen, Petri Pehkonen, Tiina Jääskeläinen, and Jorma J. Palvimo. "PIAS proteins: pleiotropic interactors associated with SUMO." Cellular and Molecular Life Sciences 66, no. 18 (2009): 3029–41. http://dx.doi.org/10.1007/s00018-009-0061-z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

von Cranach, M., and J. Valdes-Stauber. "Struktur und Entwicklung einer Institutsambulanz." Nervenheilkunde 24, no. 08 (2005): 686–95. http://dx.doi.org/10.1055/s-0038-1630007.

Full text

Abstract:

ZusammenfassungIn Folge der Psychiatrie-Enquete wurden bundesweit psychiatrische Institutsambulanzen (PIAs) installiert. Diese bemühen sich um multiprofessionelle, nachgehend aufsuchende Behandlung und Rehabilitation schwer psychisch Kranker orientiert nach Komplexleistungsprogrammen, um somit das Leistungsspektrum der niedergelassenen Psychiater im Sinne der Enquete zu ergänzen, nicht zuletzt mit Notfallbehandlung und Konsiliardienst. Die Institutsambulanz am Bezirkskrankenhaus Kaufbeuren entwickelte sich allmählich seit deren Gründung 1981 in diesem Sinne, ähnlich wie die meisten bundesweit

APA, Harvard, Vancouver, ISO, and other styles

42

Astrodjojo, Susilawati, Suratman Sudjud, and Sri Soenarsih DAS. "Effectiveness Test of Parasitization by Parasitoid Tricogramma japonicum in Controlling White Rice Stem Borer (Scirphopaga innotata)." International Journal on Food, Agriculture and Natural Resources 2, no. 1 (2021): 25–30. http://dx.doi.org/10.46676/ij-fanres.v2i1.26.

Full text

Abstract:

Rice is an essential food crop besides corn and soybeans. The need for rice each year increases along with population growth. One of the pests affecting rice is the white rice stem borer. The present research aimed to test the effectiveness and to examine the interaction between plant age and the number of Tricogramma japonicum parasitoid. The research was carried out at the Agrotechnology Laboratory of the Faculty of Agriculture, Khairun University, Ternate, and the rice fields of Bumi Restu village SP I, East Wasile district. The research design operative was a randomized block design where

APA, Harvard, Vancouver, ISO, and other styles

43

Besperi, Besperi, Gusta Gunawan, and Tessa Dwi Utari. "Pemodelan Transpor Sedimen Pantai Kualo Kota Bengkulu." Inersia: Jurnal Teknik Sipil 13, no. 1 (2021): 25–30. http://dx.doi.org/10.33369/ijts.13.1.25-30.

Full text

Abstract:

Provinsi Bengkulu merupakan salah satu daerah dengan pantai terpanjang di Indonesia. Secara umum keadaan pantai di Bengkulu telah banyak mengalami kerusakan berupa abrasi dan sedimentasi. Perubahan garis pantai disebabkan oleh faktor alam dan/atau faktor manusia. Secara geografis, Pantai Kualo terletak di bagian Barat Pulau Sumatera yang berhadapan langsung dengan Samudera Hindia. Ini berarti, seluruh tepian barat merupakan daerah laut lepas dengan sedikit pulau yang menghalanginya. Sehingga pada saat nantinya, pihak yang berwenang dapat mempertimbangkan hal-hal yang harus dilakukan dalam menj

APA, Harvard, Vancouver, ISO, and other styles

44

Heo, Kyung-Sun, Hakjoo Lee, Patrizia Nigro та ін. "PKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation". Journal of Cell Biology 193, № 5 (2011): 867–84. http://dx.doi.org/10.1083/jcb.201010051.

Full text

Abstract:

Atherosclerosis is readily observed in regions of blood vessels where disturbed blood flow (d-flow) is known to occur. A positive correlation between protein kinase C ζ (PKCζ) activation and d-flow has been reported, but the exact role of d-flow–mediated PKCζ activation in atherosclerosis remains unclear. We tested the hypothesis that PKCζ activation by d-flow induces endothelial cell (EC) apoptosis by regulating p53. We found that d-flow–mediated peroxynitrite (ONOO−) increased PKCζ activation, which subsequently induced p53 SUMOylation, p53–Bcl-2 binding, and EC apoptosis. Both d-flow and ON

APA, Harvard, Vancouver, ISO, and other styles

45

Wright, David, Raphael Gellert, Serge Gutwirth, and Michael Friedewald. "Minimizing Technology Ricks with PIAs, Precaution, and Participation." IEEE Technology and Society Magazine 30, no. 4 (2011): 47–54. http://dx.doi.org/10.1109/mts.2011.943460.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Takahashi, Yoshimitsu, and Yoshiko Kikuchi. "Cytoplasmic sumoylation by PIAS-type Siz1-SUMO ligase." Cell Cycle 7, no. 12 (2008): 1738–44. http://dx.doi.org/10.4161/cc.7.12.6156.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Shuai, Ke. "Regulation of cytokine signaling pathways by PIAS proteins." Cell Research 16, no. 2 (2006): 196–202. http://dx.doi.org/10.1038/sj.cr.7310027.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Sayad, Arezou, Mohammad Taheri, Iman Azari, Vahid Kholghi Oskoei, and Soudeh Ghafouri‐Fard. "PIAS genes as disease markers in bipolar disorder." Journal of Cellular Biochemistry 120, no. 8 (2019): 12937–42. http://dx.doi.org/10.1002/jcb.28564.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Fitri, Yulia, Bibin Sulianto, Neneng Fitrya, and Sri Fitria Retnowati. "PERANCANGAN ALAT DIGITAL PENGUKUR INTENSITAS RADIASI MATAHARI DAN LAMA PENYINARAN MATAHARI." Photon: Jurnal Sain dan Kesehatan 9, no. 1 (2018): 143–50. http://dx.doi.org/10.37859/jp.v9i1.1069.

Full text

Abstract:

Intensitas radiasi matahari dan lama penyinaran matahari mempunyai pengaruh yang besar terhadap perubahan cuaca. Alat yang digunakan untuk mengukur intensitas radiasi matahari yaitu Phyrometer sedangkan lama penyinaran matahari diukur dengan alat Campbell Stokes dengan mengukur panjang jejak bakar di pias matahari. Prototype yang dirancang bertujuan sebagai alat alternatif untuk mengukur intensitas radiasi matahari dan lama penyinaran matahari. Prototype mengukur intensitas radiasi matahari dan lama penyinaran matahari menggunakan sensor LDR. Data intensitas radiasi matahari yang diperoleh dar

APA, Harvard, Vancouver, ISO, and other styles

50

Pascual-Le Tallec, Laurent, Olivier Kirsh, Marie-Christine Lecomte, et al. "Protein Inhibitor of Activated Signal Transducer and Activator of Transcription 1 Interacts with the N-Terminal Domain of Mineralocorticoid Receptor and Represses Its Transcriptional Activity: Implication of Small Ubiquitin-Related Modifier 1 Modification." Molecular Endocrinology 17, no. 12 (2003): 2529–42. http://dx.doi.org/10.1210/me.2003-0299.

Full text

Abstract:

Abstract Molecular mechanisms underlying mineralocorticoid receptor (MR)-mediated gene expression are not fully understood but seem to largely depend upon interactions with specific coregulators. To identify novel human MR (hMR) molecular partners, yeast two-hybrid screenings performed using the N-terminal domain as bait, allowed us to isolate protein inhibitor of activated signal transducer and activator of transcription (PIAS)1 and PIASxβ, described as SUMO (small ubiquitin-related modifier) E3-ligases. Specific interaction between PIAS1 and hMR was confirmed by glutathione-S-transferase pul

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!