Academic literature on the topic 'Picralima nitida'

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Journal articles on the topic "Picralima nitida"

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Osunbor, J. O., and J. E. Osakue. "Modulatory effect of Picralima Nitida on oxidative stress: Cobalt, thiol, total protein in Drosophila melanogaster exposed to lead." Sokoto Journal of Medical Laboratory Science 8, no. 1 (2023): 78–86. http://dx.doi.org/10.4314/sokjmls.v8i1.10.

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Drosophila melanogaster, commonly known as fruit fly, vinegar fly, is a small model organism used in the study of various disciplines. D. biochemical, neurological and physiological sim ilarities with human beings and has about 75% functional homologs of genes causing diseases in humans. Picralima nitida is a diseases in humans. Picralima nitida is a therapeutic herb used in ethnomedicine for the management of several disease conditions. Theobjective of this study is to induce oxidative stress in Drosophila melanogaster using lead and determine its effect on the levels of selected oxidative st
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Odeyale, O. C., E. B. Olawuyi, A. S. Adetunji, and O. A. Akeredolu. "Evaluation of Socio-Economic and Medicinal Benefits of Picralima nitida in Ibadan South East Local Government Area, Oyo State, Nigeria." Journal of Applied Sciences and Environmental Management 28, no. 12 (2024): 4019–25. https://doi.org/10.4314/jasem.v28i12.9.

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Picralima nitida is medicinal plant that is highly valued for its wide medicinal properties throughout its distribution areas. Hence, the objective of this paper is to evaluate the socio-economic and medicinal benefits of Picralima nitida in Ibadan South East Local Government Area, Oyo State, Nigeria using appropriate standard methods. Results showed that the respondents were dominated by females (86.0%), married (66.0%) with no formal education (29.0%). Based on the likert scale rating, nine perceptional statements were agreed to except combining Picralima nitida with synthetic drug for use w
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Landry, Bangnie Gueladjibi, Kouadio Kouakou John, and Ouattara-Soro Fatou Shcherazade. "Regulatory Activity of the Aqueous Extract of Picralima nitida Seeds (Apocynaceae) on the Glycemia of Normoglycemic and Hyperglycemic Wistar Rats." Journal of Advances in Biology & Biotechnology 28, no. 1 (2025): 1018–24. https://doi.org/10.9734/jabb/2025/v28i11961.

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Picralima nitida is a plant commonly used in traditional African medicine for its antimalarial, antidiuretic, antidiarrheal, anti-inflammatory and antioxidant effects. The aim of this work was to evaluate the effect of the aqueous extract of Picralima seeds nitida on the glycemia of rats. To achieve this objective, we performed phytochemical screening using the tube revelation method. The effect of the aqueous extract of Picralima nitida seeds on glycemia was evaluated in normoglycemic and hyperglycemic rats. The screening results indicated the presence of polyphenols, catechic tannins, flavon
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Obazelu, P. A., and F. O. Ogiza. "Effect of Bi-Herbal Formula of Picralima Nitida and Cymbopogon Citratus Aqueous Leaf Extracts On Cyclooxygenase-2 and Interleukin-10 Gene Expressions in Phenyl-Hydrazine Induced Anaemia in Albino Wistar Rats." Journal of Applied Sciences and Environmental Management 28, no. 6 (2024): 1765–70. http://dx.doi.org/10.4314/jasem.v28i6.15.

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Picralima nitida and Cymbopogon citratus has been associated with anti-inflammatory and hematopoietic properties, hinting at their potential effectiveness in addressing the complications of anaemia. Investigating their impact on the gene expressions of cyclooxygenase-2 (COX-2) and Interleukin 10 (IL-10) can provide insights into their modes of operation and capacity to regulate inflammatory pathways and immune responses linked to anaemia. The aim of this study was to determine the effect of bi-herbal formula of Picralima nitida and Cymbopogon citratus aqueous leaf extracts on COX-2 and IL-10 g
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Obazelu, PA, and CO Gaius-Igboanugwo. "Effect of a bi-herbal formula extract on ETS Variant-6 and Nuclear Factor Erythroid-2 Genes expression in Phenyl-Hydrazine induced anaemia in Albino Wistar rats." Journal of Medicine and Biomedical Research 23, no. 1 (2024): 45–52. http://dx.doi.org/10.4314/jmbr.v23i1.8.

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Background: Alterations in the expressions of ETS variant-6 (ETV6) and Nuclear Factor Erythroid 2 (NFE2) may occur as part of cellular response to phenyl-hydrazine administration and the need to replenish RBCs. Understanding the relationship between phenyl-hydrazine-induced damage, erythropoiesis, and transcriptional regulation mediated by ETV6 and NFE2 provides valuable insights into the mechanisms underlying anaemia. Therefore, this study aimed to determine the effect of bi-herbal formula of Picralima nitida and Cymbopogon citratus aqueous leaf extracts on ETV6 and NFE2 gene expressions in p
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Nwankwo, N.E. Egbuonu A.C.C. *Joshua P.E. Okeke E.S. Cosmas S. Arazu A. V. and Nwodo O.F.C. "INHIBITORY EFFECT OF ETHANOL PICRALIMA NITIDA SEED EXTRACT ON MALARIA PARASITE." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 07 (2019): 13491–96. https://doi.org/10.5281/zenodo.3339388.

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<em>Parts of Picralima nitida are used by traditional medicine practitioners to treat illnesses such as diabetes and gastro-intestinal problems. Pulverized dried seeds of Picralima nitida were extracted using ethanol. The phytochemical composition of the seeds sample; LD<sub>50</sub> and the effect of seeds extract on parasitaemia were determined. Qualitative and quantitative phytochemical screening of the seeds sample revealed flavonoids, saponins, glycosides, steroids, alkaloids, soluble carbohydrates, reducing sugars, tannins, terpenoids, phenols and hydrogen cyanides. The acute toxicity te
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Ezeja, Maxwell I., Kalu K. Igwe, and Okezie V. Ikpeazu. "Comparative anti-ulcerogenic activities of the leaf, seed and stem bark hydromethanolic extracts of Picralima nitida in rats." International Journal of Basic & Clinical Pharmacology 9, no. 10 (2020): 1485. http://dx.doi.org/10.18203/2319-2003.ijbcp20204085.

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Background: Picralima nitida (Stapf) commonly called akuamma belongs to the family apocynaceae found mostly in forest areas of Africa. It is a shrub or a deciduous tree that can grow up to 35 meters in height. It has a cylindrical trunk measuring about 60 cm in diameter with white latex in its parts. The bark of the trunk is fragile and is greyish brown or black in colour.Methods: The acute oral toxicity test was done using up and down method. The anti-ulcerogenic activities of the leaf, seed and stem bark extracts were evaluated using ethanol-induced ulceration model in rats.Results: There we
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Osunbor, J. O., and A. D. Orobor. "Investigation of Some Oxidative Stress Parameters in Drosophila Melanogaster Exposed to Lead and Treated with Picralima Nitida." Journal of Applied Sciences and Environmental Management 27, no. 5 (2023): 905–10. http://dx.doi.org/10.4314/jasem.v27i5.3.

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Picralima nitida is a plant used as herb in ethno-medicine for management of several health conditions. . Drosophila melanogaster is a species of fly referred to as the fruit fly. The objective of this study was to induce oxidative stress using lead in Drosophila melanogaster and to investigate its effects on the levels of selected oxidative stress parameters (malondialdehyde, nitric oxide and hydrogen peroxide) using standard method after dividing 250 flies into nine groups (A-I). Survival studies and biochemical assays were determined by spectrometry with the homogenized flies. The mean±SD o
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MacDonald, Idu, Ovuakporie-Uvo Oghale, Eze Gerald Ikechi, and Okoro Amarachi Orji. "Hepatoprotective potentials of Picralima nitida against in vivo carbon tetrachloride-mediated hepatotoxicity." Journal of Phytopharmacology 5, no. 1 (2016): 6–9. http://dx.doi.org/10.31254/phyto.2016.5102.

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This research aimed at investigating the in vivo Carbon tetrachloride (CCl4)-mediated hepatotoxicity of methanolic seed extract of Picralima nitida (P. nitida) using Wistar rats. Twenty five (25) rats randomly selected into five groups of five animals were used in this research. Group 1 was administered Normal saline (Negative control); Group II was administered 1 ml of Carbon tetrachloride only (Positive control/ Reference drug); Group III, IV and V got 10 ml P. nitida extract + 1ml Carbon tetrachloride; 100 ml P. nitida extract + 1ml Carbon tetrachloride and 1000 ml P. nitida extract + 1ml C
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Ojo, F. T., O. A. Idowu, K. O. Ademolu, and J. O. Olukunle. "In vivo anthelmintic potentials of Gongronema latifolium and Picralima nitida against gastrointestinal parasite (Heligmosomoides bakeri)." Helminthologia 60, no. 4 (2023): 336–47. http://dx.doi.org/10.2478/helm-2023-0033.

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Summary Gastrointestinal parasites which are responsible for soil-transmitted helminthiases cause illness globally. The control of helminthiasis depends on mass distribution of anthelmintics which has been reported for its resistance, toxicity and low efficacy. In this study, anthelmintic potentials of Gongronema latifolium and Picralima nitida which have wide application in traditional medicine were determined in vivo using Heligmosomoides bakeri a naturally occurring gastro-intestinal parasite of rodents that is closely related to highly prevalent human nematode parasites. Extracts of P. nit
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Book chapters on the topic "Picralima nitida"

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Dzotam, Joachim K., and Victor Kuete. "Picralima nitida as a potential source of antibacterial agents." In Advances in Botanical Research. Elsevier, 2022. http://dx.doi.org/10.1016/bs.abr.2022.08.019.

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