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Relevant bibliographies by topics / Picroside II

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Journal articles

Academic literature on the topic 'Picroside II'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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Journal articles on the topic "Picroside II"

1

Liu, Qing Shan, Rui Liu, Hong Min He, Jian Cui, Zong Ran Pang, and Xiao Ying Yin. "Preparation and Application of Picroside II Molecularly Imprinted Ploymer for TCM Researching." Advanced Materials Research 287-290 (July 2011): 1987–90. http://dx.doi.org/10.4028/www.scientific.net/amr.287-290.1987.

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PicrosideⅡ, one of the most effective components extracted from picrorhiza, has been reported with neuronal protective activity. To isolate the picroside Ⅱ and similar structure moleculars from picrorhiza effectively, molecularly imprinted polymer (MIP) was prepared by precipitation polymerization with Picroside Ⅱ as template molecule and TRIM as cross-linkers. The MIP was with high affinity and excellent stereo-selectivity toward Picroside Ⅱ and similar structure molecular. The purity of picroside is 70% of target sample. This research might offer a novel method for the enrichment and determi

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2

Sud, Amit, Rajinder Singh Chauhan, and Chanderdeep Tandon. "Mass Spectrometric Analysis of Differentially Expressed Proteins in an Endangered Medicinal Herb,Picrorhiza kurroa." BioMed Research International 2014 (2014): 1–12. http://dx.doi.org/10.1155/2014/326405.

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Picrorhiza kurroagrown in the Northwestern Himalayan region is used in various herbal formulations but extensive harvesting of this plant has led it to near extinction. The active constituents responsible for the medicinal properties ofP. kurroahave been identified as picroside-I and picroside-II which are present in a particular ratio (1 : 1.5) in herbal formulations like Picroliv. The biosynthetic pathway of picrosides has been partially deciphered till date and needs to be elucidated completely. Review of literature revealed that no information is available as of today on the proteome analy

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3

Bhusari, S., A. Chaudhary, G. Shrangare, M. Rindhe, and P. Wakte. "PHYSICOCHEMICAL PROPERTIES DETERMINATION OF PICROSIDE-II." INDIAN DRUGS 56, no. 08 (2019): 27–37. http://dx.doi.org/10.53879/id.56.08.11807.

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The aim of the present study is to determine the physicochemical properties of Picroside-II, a phytochemical obtained from the herb of Picrorhiza kurroa. The solubility study of picroside-II shows that it has better solubility in water up to 2.46 mg/mL than organic solvents. The solubility of picroside-II in linseed oil was found to be 71.46 mg/mL. The solubility of Picroside-II in surfactant like Transcutol P and labrasol was found to be 907.80 and 535.90 mg/mL, respectively. Picroside-II had a melting point in the range of 130 to 135°C. The log P value of picroside-II was estimated using sha

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4

Wang, L., W. Lv, L. Rong, and G. Liu. "Picroside II Diminishes Oxidative Stress Induced By Cerebral Ischemic Injury In Rats." International Journal of Clinical Therapeutics and Diagnosis 1, no. 4 (2013): 27–31. https://doi.org/10.19070/2332-2926- 130006.

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Objective: To optimize the therapeutic dose and time window of picrosede II in cerebral ischemic injury in rats by orthogonal test. Methods The forebrain ischemia model was established by a bilateral common carotid artery occlusion (BCCAO) Method: Rats were randomly grouped according to orthogonal experimental design and treated by injecting picroside II intraperitonenally at different ischemic times with different doses. The concentration of lipid perioxide malondialdehyde (MDA) in serum and brain was determined by thiobarbituric acid assay. The activity of superoxide dismutase (SOD

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5

Wang, Fanchen, Jiacong Xiao, Miao Li та ін. "Picroside II suppresses chondrocyte pyroptosis through MAPK/NF-κB/NLRP3 signaling pathway alleviates osteoarthritis". PLOS ONE 19, № 8 (2024): e0308731. http://dx.doi.org/10.1371/journal.pone.0308731.

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Background Picroside II (P-II) is the main bioactive constituent of Picrorhiza Kurroa, a traditional Chinese herb of interest for its proven anti-inflammatory properties. Its beneficial effects have been noted across several physiological systems, including the nervous, circulatory, and digestive, capable of treating a wide range of diseases. Nevertheless, the potential of Picroside II to treat osteoarthritis (OA) and the mechanisms behind its efficacy remain largely unexplored. Aim This study aims to evaluate the efficacy of Picroside II in the treatment of osteoarthritis and its potential mo

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6

Do Yen, Nhi, Huong Nguyen Thi Anh, Phuong Pham Minh, Nhi Trinh Yen, Thuy Le Thi, and Trang Vu Thi. "Simultaneous determination of picroside I and picroside II in dietary supplements by high performance liquid chromatography with PDA detector." Heavy metals and arsenic concentrations in water, agricultural soil, and rice in Ngan Son district, Bac Kan province, Vietnam 7, no. 3 (2024): 226–36. http://dx.doi.org/10.47866/2615-9252/vjfc.4352.

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Picroside I and picroside II are two compounds found in the Picrorhiza Kurroa plant, which have anti-cirrhosis, antioxidant, anti-inflammatory, fever, and asthma effects, etc. They are included in the ingredients of many dietary supplement products that help protect the liver and bile, prevent oxidation, etc. Therefore, determining the content of these two active ingredients in dietary supplements is necessary to evaluate product quality. In this study, highperformance liquid chromatography (HPLC-PDA) was used to simultaneously determine picroside I and picroside II in dietary supplements. The

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7

Lee, Kiram, Jin Choi, Bo Kyong Choi, et al. "Picroside II Isolated from Pseudolysimachion rotundum var. subintegrum Inhibits Glucocorticoid Refractory Serum Amyloid A (SAA) Expression and SAA-induced IL-33 Secretion." Molecules 24, no. 10 (2019): 2020. http://dx.doi.org/10.3390/molecules24102020.

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Chronic obstructive pulmonary disease (COPD) is a major inflammatory lung disease characterized by irreversible and progressive airflow obstruction. Although corticosteroids are often used to reduce inflammation, steroid therapies are insufficient in patients with refractory COPD. Both serum amyloid A (SAA) and IL-33 have been implicated in the pathology of steroid-resistant lung inflammation. Picroside II isolated from Pseudolysimachion rotundum var. subintegrum (Plantaginaceae) is a major bioactive component of YPL-001, which has completed phase-2a clinical trials in chronic obstructive pulm

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8

Ma, Chunmei, та Aijie Shi. "Picroside II prevents inflammation injury in mice with diabetic nephropathy via TLR4/NF-κB pathway". Quality Assurance and Safety of Crops & Foods 13, № 4 (2021): 38–43. http://dx.doi.org/10.15586/qas.v13i4.984.

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The purpose of this study was to investigate the therapeutic effects of picroside II on diabetic nephropathy and reveal the involved underlying signal pathway. Male Sprague–Dawley (SD) mice were used to construct an animal model of streptozotocin (STZ)-induced diabetic nephropathy. Body weight and fasting blood glucose values were recorded. Enzyme-linked immunosorbent assay (ELISA) was used to measure the levels of proteinuria, blood urea nitrogen (BUN), serum creatinine (Scr), interleukin (IL)-1β, IL-6, monocyte chemoattractant protein-1 (MCP-1) and necrosis factor alpha (TNF-α). Protein expr

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9

Li, Ting, Jian-Wen Liu, Xiao-Dong Zhang, Ming-Chuan Guo, and Guang Ji. "The Neuroprotective Effect of Picroside II from Hu-Huang-Lian against Oxidative Stress." American Journal of Chinese Medicine 35, no. 04 (2007): 681–91. http://dx.doi.org/10.1142/s0192415x0700517x.

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Picroside II is an active constituent extracted from the traditional Chinese medicine (TCM) Hu-Huang-Lian. To evaluate the neuroprotective effect of picroside II, PC12 cells were treated with glutamate in vitro and male ICR mice were treated with AlCl 3in vivo. Pre-treatment of PC12 cells with picroside II could enhance the cell viability and decrease the level of intracellular reactive oxygen species (ROS) induced by glutamate. By DNA fragmentation and flow cytometry assay, picroside II (1.2 mg/ml) significantly prevented glutamate-induced cell apoptosis. In the animal study, amnesia was indu

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10

Xie, Haili, Xiaojie Lu, Weiqiang Jin, et al. "Pharmacokinetics of Picroside I, II, III, IV in Rat Plasma by UPLCMS/ MS." Current Pharmaceutical Analysis 16, no. 4 (2020): 438–45. http://dx.doi.org/10.2174/1573412916666191022161501.

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Background: Modern pharmacological studies show that rhizoma coptidis has protective effects on the liver, gallbladder, kidney, cerebral ischemia-reperfusion, local hypoxia injury, antiinflammatory, bone injury, nerve cells and myocardial cells. The effective components have been isolated from picroside I, II, III and IV. Introduction: A selective and sensitive ultra-performance liquid chromatography electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) method was developed for the simultaneous quantitative determination of picroside I, II, III and IV in rat plasma to aid the pharm

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