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1

Mohamed Yoosuf, Ahamed Badusha, Geraldine Workman, Monica M. O'Toole, et al. "Use of sector analysis of I-125 permanent prostate brachytherapy to evaluate and compare pre- and postimplant dosimetry." Journal of Clinical Oncology 30, no. 5_suppl (2012): 242. http://dx.doi.org/10.1200/jco.2012.30.5_suppl.242.

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242 Background: To evaluate 12 sector analysis in the assessment and comparison of pre- and post- implant dosimetric parameters during the development of an I-125 prostate brachytherapy (PPB) service. Methods: 50 consecutive men being treated with PPB had dose volume analysis in 12 sectors of their pre implant ultrasound (PIUS) and post implant CT (PICT) data using a Variseed 8.0 treatment planning system. PIUS dosimetry was performed 2 weeks prior to implantation and PICT dosimetry 4 weeks post implant. Individual sectors were created by dividing the cranio-caudal prostate length into 3 equal
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2

Hussain, Nadir, Sadam Hussain, Mujahid Mehdi, et al. "Introducing Deep Eutectic Solvents as a Water-Free Dyeing Medium for Poly (1,4-cYclohexane Dimethylene Isosorbide Terephthalate) PICT Nanofibers." Polymers 13, no. 16 (2021): 2594. http://dx.doi.org/10.3390/polym13162594.

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Water, one of the most priceless sources of life, is becoming dangerously threatened and contaminated due to population growth, industrial development, and climatic variations. The drainage of industrial, farming, and municipal sewage into drinking water sources pollutes the water. The textile processing industry is one of the major consumers of water. Herein, the idea of water-free dyeing of electrospun poly (1, 4-cyclohexane dimethylene isosorbide terephthalate) PICT nanofibers is proposed. For this, two different deep eutectic solvents (DE solvents) were introduced as an alternative to wate
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3

Hoppensteadt, Debra A., Josephine Cunanan, Jeanine M. Walenga, and Jawed Fareed. "Development of Prothrombinase Induced Clotting Time (Pefakit ®, PiCT) Assay and its Validation in the Monitoring of Anti-Xa and Anti-FIIa Drugs." Blood 104, no. 11 (2004): 1858. http://dx.doi.org/10.1182/blood.v104.11.1858.1858.

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Abstract Unfractionated heparin (UFH), low molecular weight heparin (LMWH), fondaparinux, danaparoid, direct and indirect (via a cofactor) acting anti-FIIa and anti-Xa anticoagulant drugs are being used in patients for the prophylaxis and treatment of thrombosis. The aPTT does not reliably measure the effects of these drugs. Therefore, there is no simple/reliable method for monitoring patients administered these drugs, particularly those with renal insufficiency and obesity. The newly developed Prothrombinase Induced Clotting Time (PiCT) assay (Pefakit®; Pentapharm, Ltd.; Basel, Switzerland) w
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4

Hoppensteadt, D., M. Tobu, R. Wahi, et al. "Comparative Study on the Anticoagulant Effects of Low Molecular Weight Heparins as Measured by Whole Blood Act, Anti-Xa and a Newly Developed Prothrombinase Induced Clotting Time (PiCT) Assay." Blood 106, no. 11 (2005): 4148. http://dx.doi.org/10.1182/blood.v106.11.4148.4148.

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Abstract Low Molecular Weight Heparins (LMWHs) are currently developed for anticoagulation in various intravenous indications such as DVT treatment and percutaneous interventions (PCI). Traditionally, these drugs are administered in anti-Xa units. The purpose of this study was to compare the relative levels of anticoagulation produced by different LMWHs in whole blood ACT (Hemochron), an amidolytic anti-Xa method and a plasma-based global anticoagulant assay, the PiCT test (Pentapharm, Basel, Switzerland). Various LMWHs such as dalteparin, enoxaparin, reviparin and a synthetic pentasaccharide
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5

Hoppensteadt, Debra, Jeanine M. Walenga, Josephine Cunanan, et al. "Selection of a Suitable Rapid Turn Around and Sensitive Test for the Laboratory Monitoring of Newer Oral Anticoagulants, Rivaroxaban, Apixaban and Dabigatran,." Blood 118, no. 21 (2011): 3363. http://dx.doi.org/10.1182/blood.v118.21.3363.3363.

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Abstract Abstract 3363 Recently, several of the newer oral anticoagulants such as Rivaroxaban (Bayer Healthcare) (R) Apixaban (BMS/Pfizer) (A) and Dabigatran (Boehringer Ingleheim) (D) have been approved for different indications in the US and European countries. Although the monitoring is not required or promoted to manage the approved dosages of these drugs in different indications, population based bleeding complications with some of these agents have been reported warranting the monitoring of these drugs to optimize therapy. Conventionally the Xa based drugs such as Rivaroxaban and Apixaba
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6

Calatzis, Andreas, Armin J. Reininger, and Michael Spannagl. "Assessment of Heparins, Heparinoids and Direct Thrombin Inhibitors Using a New FXa-and RVV-V-Based Assay." Blood 104, no. 11 (2004): 1856. http://dx.doi.org/10.1182/blood.v104.11.1856.1856.

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Abstract UFH and direct thrombin inhibitors are usually monitored using the activated partial thromboplastin time (aPTT), which has many known limitations. These include non-linear-dose response-relationships as well as a high variability among different reagents. In addition the aPTT has a low sensitivity towards low molecular weight heparin (LMWH). Newer methods such as chromogenic substrate analysis, ecarin clotting time or the Heptest assay have provided improved sensitivity and specificity, but still have not reached broad application in routine or emergency laboratories. The performance
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7

Hoppensteadt, Debra, Daneyal Syed, Mateja Jezovnik, et al. "Circulating Levels of Rivaroxaban Provide Different Results in Different Clot Based and Amidolytic Assays. a Study on Patients Treated with Two Different Dosages of Rivaroxaban." Blood 124, no. 21 (2014): 5084. http://dx.doi.org/10.1182/blood.v124.21.5084.5084.

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Abstract Introduction: Rivaroxaban is an orally active anti-Xa agent which is approved for various clinical indications including DVT/ PE management. Although monitoring of this agent is not commonly required, in certain clinical conditions circulating anti-Xa levels may be useful for the optimal management of patients treated with this drug. The circulating plasma levels of anti-Xa activity can be obtained by using amidolytic methods; however, their relevance to observed bleeding and antithrombotic effects is not clear. Plasma based assays, such as the PT/APTT, are largely dependent on other
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8

Iwayama, I., S. Ueda, A. Yamamoto, et al. "Jc enhancement of high density MgB2 bulk made by Premix-PICT-Diffusion method." Physica C: Superconductivity and its Applications 460-462 (September 2007): 581–82. http://dx.doi.org/10.1016/j.physc.2007.04.108.

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9

Hoppensteadt, D., W. Jeske, D. Fareed, et al. "Clinical and Laboratory Validation of the 2nd International Standard of Low Molecular Weight Heparin (IS 2003-01/608) in the Anti-Xa, Anti-LIA Heptest and Prothrombinase Induced Clotting (PiCT) Tests." Blood 106, no. 11 (2005): 4147. http://dx.doi.org/10.1182/blood.v106.11.4147.4147.

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Abstract Background: Because of the relative insensitivity of the global clot based assays such as the activated partial thromboplastin time (APTT), the low molecular weight heparins (LMWHs) are potency evaluated/optimized in the anti-Xa (AXa) and heptest. A new clot based assay namely, prothrombin induced clotting time (PiCT) is sensitive to the anticoagulant effects of LMWHs and related drugs. As the LMWHs are standardized using the anti-Xa methods, using the International Standards, this study was designed to cross validate the 2nd International Standard for LMWHs(NIBSC 01/608) in various a
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10

Hall, T. F., R. C. Waterfall, G. J. Kakabadse, E. O. Olatoye, R. Perry, and A. E. Tipping. "Computer-Controlled On-Line Moisture Measurement in Organic Solvents Using a Novel Potentiometric Technique." Measurement and Control 22, no. 8 (1989): 240–44. http://dx.doi.org/10.1177/002029408902200803.

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A microcomputer-based monitoring system for the determination of residual water in organic solvents using ion-selective electrodes in a novel potentiometric method, called the proton iso-concentration technique (PICT), has been developed at UMIST. In the monitor, a sample stream is bled off and mixed with a buffer solution before passing through a cell containing a pH glass electrode, a reference electrode and an automatic temperature compensation probe. The instrument is calibrated with standard solutions containing water in the same solvent. The automatic monitoring system comprises a microc
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11

Harenberg, Job, Ingrid Joerg, Christel Weiss, and Tivadar Fenyvesi. "Long Acting Anticoagulant Effects of Idraparinux in Patients Treated for Prophylaxis of Recurrent Venous Thromboembolism." Blood 108, no. 11 (2006): 899. http://dx.doi.org/10.1182/blood.v108.11.899.899.

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Abstract Prophylaxis of recurrent venous thromboembolism (VTE) has been investigated in patients with acute VTE participating in the VanGogh DVT, PE and Extension studies for a minimum of 6 months. These patients were given a fixed dose of Idraparinux once a week subcutaneously without coagulation monitoring. The VanGogh DVT/PE studies randomized patients to Idraparinux versus INR-adjusted Warfarin. Patients were then able to follow on to the double-blind VanGogh Extension study comparing Idraparinux versus placebo. Determination of the anticoagulant effects may still be necessary for patients
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12

Fenyvesi, T., I. Jörg, and J. Harenberg. "Effect of Phenprocoumon on Monitoring of Lepirudin, Argatroban, Melagatran and Unfractionated Heparin with the PiCT Method." Pathophysiology of Haemostasis and Thrombosis 32, no. 4 (2002): 174–79. http://dx.doi.org/10.1159/000070423.

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13

SHIMADA, Yusuke, Tetsuya OHASHI, Satoshi HATA, et al. "Influences of Microstructure on Critical Current Properties in MgB2 Superconducting Bulk Fabricated using a Premix-PICT Method." TEION KOGAKU (Journal of the Cryogenic Society of Japan) 44, no. 12 (2009): 613–20. http://dx.doi.org/10.2221/jcsj.44.613.

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14

Siddiqui, Fakiha, Debra Hoppensteadt, Walter Jeske, Omer Iqbal, Alfonso Tafur, and Jawed Fareed. "Factor Xa Inhibitory Profile of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban Does Not Fully Reflect Their Biologic Spectrum." Clinical and Applied Thrombosis/Hemostasis 25 (January 1, 2019): 107602961984752. http://dx.doi.org/10.1177/1076029619847524.

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The currently available oral anti-Xa agents are claimed to produce their anticoagulant and antithrombotic effects solely by the inhibition of factor Xa. This study profiled various anti-Xa drugs in routinely used laboratory assays to demonstrate that their effects are not solely related to the anti-Xa activities. Apixaban, betrixaban, edoxaban, and rivaroxaban were obtained commercially. Native and citrated whole blood was used for the activated clotting time (ACT) and thromboelastography (TEG). Citrated plasma was used for monitoring the prothrombin time (PT), activated partial thromboplastin
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15

Siddiqui, Fakiha, Debra Hoppensteadt, Emily Bontekoe, Ambar Farooqui, Walter Jeske, and Jawed Fareed. "Comparative Anticoagulant and Thrombin Generation Inhibitory Profile of Heparin, Sulodexide and Its Components." Clinical and Applied Thrombosis/Hemostasis 26 (January 1, 2020): 107602962095491. http://dx.doi.org/10.1177/1076029620954913.

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Introduction: Sulodexide represents a mixture of fast-moving heparin (FMH) and dermatan sulfate (DS) and has been used for the management of venous diseases such as DVT and related disorders. The purpose of this study is to compare sulodexide and its components with unfractionated heparin (UFH) to determine its suitability for the indications in which UFH is used. Materials and Method: Active pharmaceutical ingredients (API) versions of sulodexide, FMH and DS were obtained from Alfasigma. API versions of UFH were obtained from Medefil Inc. Normal human citrated plasma was obtained from blood b
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16

Bansal, Vinod, Kristiyana Kaneva, Debra Hoppensteadt, Josephine Cunanan, and Jawed Fareed. "Variations in the Circulating Heparin Levels During Maintenance Hemodialysis in End Stage Renal Disease Patients." Blood 120, no. 21 (2012): 3412. http://dx.doi.org/10.1182/blood.v120.21.3412.3412.

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Abstract Abstract 3412 Introduction: Unfractionated heparin has remained the anticoagulant of choice for hemodialysis patients. The anticoagulation facilitates blood flow through the dialysis circuit and assures the patency of the dialysis membrane. Wide variations in the heparinization responses have been observed in patients undergoing this procedure. The purpose of this investigation was to measure circulating heparin levels in patients prior to and after hemodialysis. Methods: This study included 119 ESRD patients undergoing maintenance hemodialysis after appropriate IRB approval and patie
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17

Kristensen, Kerstin, and Anders Möller. "Development of Pict-O-Stat: violence – focus on experiences of violence and a survey that can be completed by the individuals themselves." Journal of Adult Protection 19, no. 3 (2017): 146–57. http://dx.doi.org/10.1108/jap-08-2016-0018.

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Purpose The purpose of this paper is to find a method that makes it possible for people with intellectual disabilities to independently contribute to population-based research in areas that is sensitive. It is important to be able to answer questionnaires independently in research areas that are sensitive because the informant maybe does not want to ask for help to answer a questionnaire about sexual violence, domestic violence, etc. Maybe they not even have talked to anyone about their experiences and then have to tell a staff/relative that helps them to complete the survey is probably unthin
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18

Antwi, Kwadwo, Patricia Wiesner, Elmar M. Merkle, et al. "Investigating difficult to detect pancreatic lesions: Characterization of benign pancreatic islet cell tumors using multiparametric pancreatic 3-T MRI." PLOS ONE 16, no. 6 (2021): e0253078. http://dx.doi.org/10.1371/journal.pone.0253078.

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Introduction Pancreatic islet-cell tumors (PICT) often present with atypical signal-characteristics and are often missed on preoperative imaging. The aim of this study is to provide a multiparametric PICT characterization and investigate factors impeding PICT detection. Material and methods This is a detailed MRI analysis of a prospective, monocenter study, including 49 consecutive patients (37 female, 12 male; median age 50) with symptoms due to endogenous hyperinsulinemic hypoglycemia (EHH) and mostly negative prior-imaging. All patients received a 3-T MRI and a 68Ga-DOTA-exendin-4-PET/CT. P
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Campillo-Cora, Claudia, Diego Soto-Gómez, Manuel Arias-Estévez, Erland Bååth, and David Fernández-Calviño. "Bacterial community tolerance to Cu in soils with geochemical baseline concentrations (GBCs) of heavy metals: Importance for pollution induced community tolerance (PICT) determinations using the leucine incorporation method." Soil Biology and Biochemistry 155 (April 2021): 108157. http://dx.doi.org/10.1016/j.soilbio.2021.108157.

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20

Pérez Montilla, CA, S. Moroni, N. González, G. Moscatelli, JM Altcheh, and F. García Bournissen. "P38 Identification of Nifurtimox metabolites in urine of pediatric Chagas disease patients by UHPLC-MS/MS." Archives of Disease in Childhood 104, no. 6 (2019): e32.3-e33. http://dx.doi.org/10.1136/archdischild-2019-esdppp.76.

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BackgroundNifurtimox (NFX) is one of the only 2 available drugs for the treatment of Chagas disease, a parasitic disease endemic to Latin America. In spite of widespread use of this medication, little is known regarding its metabolism, particularly in children.The objective of this study was to develop a method to identify NFX metabolites in human samples, and apply it to the discovery of NFX metabolites in urine from pediatric patients undergoing treatment for Chagas disease.MethodsUrine was collected from 12 pediatric patients and 8 healthy volunteers (controls), and anonymized before analys
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Shimels, Tariku. "The Trend of Health Service Utilization and Challenges Faced During the COVID-19 Pandemic at Primary Units in Addis Ababa: A Mixed-Methods Study." Health Services Research and Managerial Epidemiology 8 (January 1, 2021): 233339282110311. http://dx.doi.org/10.1177/23333928211031119.

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Introduction: The COVID-19 pandemic has imposed an extraordinary challenge to the health and socio-economic facet of nations globally. Health facilities have encountered tremendous challenges to contain service delivery at all levels. This study aims to assess the trend of health service utilization and challenges faced during the COVID-19 pandemic at primary units in Addis Ababa, Ethiopia. Method: A multi-facility-based cross-sectional study was conducted in Addis Ababa between 1 and 30 of August 2020. A mixed-methods design was employed, and both quantitative and qualitative data were collec
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Greene, Rachel, Cydni N. Williams, and Trevor A. Hall. "A-38 Post-Intensive Care Syndrome in a Cohort of School-Aged Children & Adolescents Receiving Integrated Care Via a Pediatric Critical Care & Neurotrauma Recovery Program." Archives of Clinical Neuropsychology 36, no. 6 (2021): 1079. http://dx.doi.org/10.1093/arclin/acab062.56.

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Abstract Objective We aimed to identify critical issues related to Post-Intensive Care Syndrome (PICS) through an integrated model of care whereby children and families participate in follow-up clinics with a neuropsychologist and a critical care physician. To demonstrate the impact of direct assessment, we present pilot program findings on early identification and treatment of PICS in a cohort of school-aged children and adolescents through a combination of multi-professional direct assessment and parent proxy questionnaires. Method 64 children and adolescents ages 8–17 years participated in
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Dong, Lei, Siyu Zhai, Bukang Wang, Liang Dong, Junyuan Wang, and Ruimin Shi. "Single Pick Cutting Rock Load Identification Based on Improved Regularization Method." Shock and Vibration 2021 (July 12, 2021): 1–9. http://dx.doi.org/10.1155/2021/9994569.

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To explore the relationship between the cutting vibration and the cutting load of a single pick, this paper studied a new method for a single pick cutting rock load identification. This paper improved the low accuracy problem of the regularization method in the inverse process of frequency response function in the traditional load identification method by introducing a filter operator. By combining the inverse pseudoexcitation method and the improved regularization method, the identification of the load dependent on the vibration signal was realized. A single pick cutting rock test equipment w
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Elias, Beth L., Shea Polancich, Carolynn Jones, and Sean Colvin. "Evolving the PICOT Method for the Digital Age: The PICOT-D." Journal of Nursing Education 54, no. 10 (2015): 594–99. http://dx.doi.org/10.3928/01484834-20150916-09.

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25

James, Gareth, and Trevor Hastie. "The Error Coding Method and PICTs." Journal of Computational and Graphical Statistics 7, no. 3 (1998): 377. http://dx.doi.org/10.2307/1390710.

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26

James, Gareth, and Trevor Hastie. "The Error Coding Method and PICTs." Journal of Computational and Graphical Statistics 7, no. 3 (1998): 377–87. http://dx.doi.org/10.1080/10618600.1998.10474782.

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Ryu, Soyoung, Byron Gallis, Young Ah Goo, Scott A. Shaffer, Dragan Radulovic, and David R. Goodlett. "Comparison of a Label-Free Quantitative Proteomic Method Based on Peptide Ion Current Area to the Isotope Coded Affinity Tag Method." Cancer Informatics 6 (January 2008): CIN.S385. http://dx.doi.org/10.4137/cin.s385.

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Recently, several research groups have published methods for the determination of proteomic expression profiling by mass spectrometry without the use of exogenously added stable isotopes or stable isotope dilution theory. These so-called label-free, methods have the advantage of allowing data on each sample to be acquired independently from all other samples to which they can later be compared in silico for the purpose of measuring changes in protein expression between various biological states. We developed label free software based on direct measurement of peptide ion current area (PICA) and
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28

Wang, Yanxiang, Daolong Yang, Bangsheng Xing, Wenqiang Yu, Jie Guo, and Hao Xu. "Recent Patents on Conical Pick and Flat Pick for Coal Mining." Recent Patents on Mechanical Engineering 13, no. 4 (2020): 295–302. http://dx.doi.org/10.2174/2212797613999200525134542.

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Background: Coal mining machines are the primary equipment used for the comprehensive mining of medium and thick coal seams. A shield machine is used to modify the geological structure of the soil, especially in urban subway tunnel engineering. The cutting and tunneling equipment have greatly improved the efficiency of coal seam mining and rock tunneling construction, but the consumption of picks in mining and tunneling is very high. Objective: In order to reduce the consumption of picks, it is necessary to obtain the change of temperature inside the pick in the process of cutting. Methods: Th
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He, Chong Dong, Hai Chen Qin, and Jian Kui Chen. "A Fuzzy Adaptive Force Controller Design of Robotic Manipulators for Pick-and-Placing Thin Brittle Materials." Applied Mechanics and Materials 303-306 (February 2013): 1666–73. http://dx.doi.org/10.4028/www.scientific.net/amm.303-306.1666.

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For the pick-and-place operations of GDL, this paper presents and obtains the control system model using system identification method, and analyzes three distinct stages for the motion characteristics in pick-and-place operations. To satisfy the stick requirements for contact force control, a force controller based on fuzzy adaptive PID algorithm and a position controller based on feed-forward control are presented and designed. Simulations are carried out to verify the feasibility and effectiveness of the proposed control method. The above control strategies and methods are applied to pick up
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Bołoz, Łukasz, Antoni Kalukiewicz, Greg Galecki, Liubomyr Romanyshyn, Taras Romanyshyn, and Rafael Barrionuevo Giménez. "Conical Pick Production Process." New Trends in Production Engineering 3, no. 1 (2020): 231–40. http://dx.doi.org/10.2478/ntpe-2020-0019.

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AbstractOne of the basic methods of mechanical rock mining is cutting, which faces increasingly difficult working conditions. Despite the rapid development of machines used in underground and opencast mining as well as in tunnel building, construction industry and road engineering, the problem of insufficient durability of mining tools remains unsolved. In addition to drilling and, to a lesser extent, planing, cutting provides a huge market for tools. Currently, the process of cutting is mainly based on conical picks. The cutterheads of cutting machines are equipped with several dozen, and fre
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Kim, Sam-Taek. "The Wireless Controller using PCB mounted PIC MICOM Control Method for Tactical Training." Journal of the Institute of Webcasting, Internet and Telecommunication 12, no. 4 (2012): 51–56. http://dx.doi.org/10.7236/jiwit.2012.12.4.51.

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Monsky, Wayne L., Armando S. Garza, Shaun Loh, and Daniel P. Link. "Snare Technique for the Placement of a Peripherally Inserted Central Catheter in the Neonatal and Pediatric Patient." Journal of Vascular Access 11, no. 2 (2010): 100–105. http://dx.doi.org/10.1177/112972981001100203.

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Purpose The placement of a peripherally inserted central catheter (PICC) for neonatal or pediatric patients may at times be technically challenging. We describe an alternate method of placing a PICC in neonatal and pediatric patients with difficult venous access. Methods An Amplatz gooseneck snare is advanced from the femoral vein to the basilic vein, as a target for puncture and guidewire positioning, allowing PIcc placement. Between 1999 and 2006, 44 PICCs were placed in the manner described. The medical records were reviewed allowing for up to 7 yrs of patient follow-up. Results Ninety-five
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Nababan, Sudarwati, Maritjie Fransina Papilaya, and Muchlis Achsan Udji Sofro. "Hubungan Pengetahuan dan Persepsi Ibu dengan Pemanfaatan Layanan Provider Initiated HIV Testing Counselling di Maluku." Medica Hospitalia : Journal of Clinical Medicine 7, no. 1 (2020): 6–11. http://dx.doi.org/10.36408/mhjcm.v7i1.420.

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Latar belakang : Maluku Tenggara berada pada peringkat ke-2 tertinggi kasus HIV/AIDS dari 11 kabupaten di Maluku. Ibu rumah tangga di Wilayah Kerja Puskesmas Kolser rentan tertular HIV dari suaminya. Rumah tangga daerah ini 40% tidak tinggal bersama karena suami bekerja tidak menetap, selain itu di daerah ini juga terdapat lokalisasi. Ibu hamil yang memanfaatkan layanan Provider Initiated HIV Testing Counselling tahun 2017 sebanyak 76% dari 321 kunjungan, data ini menunjukkan Puskesmas Kolser belum mencapai target Maluku Tenggara terkait program yakni 89%. 
 Tujuan : Mengetahui faktor yan
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Kuitunen, Anne, Jari Petäjä, Sorella Ilveskero, Riitta Lassila, and Peter Raivio. "Monitoring high-dose heparinization during cardiopulmonary bypass – A comparison between prothrombinase-induced clotting time (PiCT) and two chromogenic anti-factor Xa activity assays." Thrombosis and Haemostasis 99, no. 02 (2008): 427–34. http://dx.doi.org/10.1160/th07-04-0307.

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SummaryHeparinization requires monitoring, but optimal methods for measuring the anticoagulant effects of heparin remain to be determined. We compared prothrombinase-induced clotting time (PiCT) and two chromogenic anti-factor Xa activity (anti-Xa) assays in monitoring high-dose heparinization during cardiopulmonary by-pass (CPB). Heparin effects were serially measured with PiCT and two anti-Xa assays in 100 patients. Antithrombin and protein C activities were measured preoperatively, and antithrombin activity was measured during CPB. Activation of coagulation was assessed with measurements of
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Hoppensteadt, Debra, Emily Bontekoe, Fakiha Siddiqui, et al. "Prothrombinase Induced Clotting Time Is More Sensitive then aPTT and PT and Can be Used for the Monitoring of Anti-Xa Agents in Whole Blood and Plasma." Blood 134, Supplement_1 (2019): 3374. http://dx.doi.org/10.1182/blood-2019-131221.

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Introduction: Currently there are four commercially available oral anti-Xa agents namely apixaban, betrixaban, edoxaban and rivaroxaban available for indication specific clinical use. All agents used are at a fixed dosage and their use may be associated with potential hemorrhagic complications. Although factor Xa inhibitory effect is considered to be a surrogate marker for the biologic action of these drugs we have demonstrated that factor Xa inhibitory profile of apixaban, betrixaban, edoxaban, and rivaroxaban does not fully reflect their biologic spectrum (https://doi.org/10.1177/10760296198
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Kang, Sang Hun, and Eunji Jun. "Numerical Simulation of an Electric Thruster Plume Behavior Using the PIC-DSMC Method." Journal of the Korean Society of Propulsion Engineers 25, no. 4 (2021): 1–11. http://dx.doi.org/10.6108/kspe.2021.25.4.001.

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Kobayashi, S., H. Karasudani, Y. Koguchi, et al. "Endovascular Treatment for Ruptured VA Dissecting Aneurysm Involving the Origin of PICA." Interventional Neuroradiology 10, no. 1_suppl (2004): 173–79. http://dx.doi.org/10.1177/15910199040100s130.

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Ruptured vertebral artery dissecting aneurysms (VADA) re-bleed frequently especially during first 24 hours, which makes the prognosis of the patients with this disease poor. Recently endovascular trapping with detachable platinum coils at an acute stage has been done for preventing re-bleeding. However, for the cases with dissecting aneurysm involving the origin of the posterior inferior cerebellar artery (PICA), these methods are hardly indicated because of the risk of ischemic complication in the PICA territory. We proposed a simple and effective therapeutic method for these cases. We occlud
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Cho, Wan Goo. "Stability of W/O Nanoemulsions with Low Viscosity Prepared by PIC Method." Journal of the Society of Cosmetic Scientists of Korea 42, no. 2 (2016): 127–33. http://dx.doi.org/10.15230/scsk.2016.42.2.129.

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Kimple, Travis, Niaman Nazir, and Chad M. Cannon. "Anatomically Associated Venous Thromboembolism in Patients With Peripherally Inserted Central Catheters." Journal of the Association for Vascular Access 22, no. 4 (2017): 182–87. http://dx.doi.org/10.1016/j.java.2017.09.001.

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Abstract Background: Peripherally inserted central catheters (PICCs) are ubiquitous in modern hospitals, but are associated with venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and/or pulmonary embolism (PE). We retrospectively examined this association in hospitalized patients, highlighting anatomically associated VTEs (those with DVT in the PICC extremity). Methods: Charts with an International Classification of Diseases, Ninth Revision (ICD9) code for VTE were collected from a discharge database of PICC-managed patients at a tertiary hospital. A sample (52.3%) of the
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Lu, Zhenguo, Qingliang Zeng, Zhihai Liu, Guanshun Gao, and Peisi Zhong. "Research on Cutting Characteristics of Rock Plate with Two Sides Fixed and Two Sides Free." Advances in Materials Science and Engineering 2020 (October 23, 2020): 1–15. http://dx.doi.org/10.1155/2020/4198010.

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Conical pick wear is an urgent problem in the roadway excavation caused by hard rock difficult to break. The traditional method of increasing cutting power to improve cutting performance of conical pick significantly increases pick wear. In the paper, a saw blade and conical pick combined cutting method is proposed based on increased free surface. To research the fracture morphology and cutting force of rock plate, theoretical, numerical, and experimental methods are used. By theoretical research, the bending mechanical model of rock plate bending is established. The cutting position and the j
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Brandão, Fabiana A. S., Benner G. Alves, Kele A. Alves, et al. "Laparoscopic ovarian biopsy pick-up method for goats." Theriogenology 107 (February 2018): 219–25. http://dx.doi.org/10.1016/j.theriogenology.2017.10.042.

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Hamada, Jun-ichiro, Tatemi Todaka, Shigetoshi Yano, Yutaka Kai, Motohiro Morioka, and Yukitaka Ushio. "Vertebral artery—posterior inferior cerebellar artery bypass with a superficial temporal artery graft to treat aneurysms involving the posterior inferior cerebellar artery." Journal of Neurosurgery 96, no. 5 (2002): 867–71. http://dx.doi.org/10.3171/jns.2002.96.5.0867.

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Object. In patients with aneurysms that require occlusion of the posterior inferior cerebellar artery (PICA), revascularization of this artery should be performed. A novel surgical method for revascularization of the PICA is presented. Methods. After a segment of the superficial temporal artery (STA) was harvested, the aneurysm was treated by trapping, followed by placement of a vertebral artery (VA)—PICA bypass in which the STA segment was used as a graft. When the length of the proximal PICA was inadequate, the distal end of the STA was anastomosed to the proximal PICA in an end-to-side fash
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Park, Jong-Cheon, Kyung-Mo Kim, and Kwang-Ho Kim. "Minimization of Warpage in Plastic Injection-Molded Parts Based on the ‘Pick-the-Winner' Rule and Design Space Reduction Method." Journal of the Korea Academia-Industrial cooperation Society 11, no. 4 (2010): 1171–77. http://dx.doi.org/10.5762/kais.2010.11.4.1171.

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Wu, Shih-Jeh, Hsiang-Chen Hsu, and Wen-Fei Lin. "GLASS CUTTING WITH ELONGATION OPTICS IN COMPARISON TO CONVENTIONAL METHODS BY LASER." Transactions of the Canadian Society for Mechanical Engineering 40, no. 5 (2016): 923–32. http://dx.doi.org/10.1139/tcsme-2016-0076.

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In this study, the authors applied a pico-second 532 nm laser with state of art elongated optics on cutting soda lime glasses and compared the results with three other methods by conventional focusing technique namely; dice-and break, direct wobbling cut (both by UV laser), and stealth cut (by pico-second IR laser). The dice-and-break method has the fastest speed, however, the roughness is poor. The wobbling method is poor in both roughness and cutting speed. The dual-focused beam has the smoothest cross-section with fast speed in one step. Of the four methods, the elongation optics has the be
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Fager, Patrik. "Kit preparation for mixed-model assembly: efficiency impact of confirmation methods." Industrial Management & Data Systems 119, no. 3 (2019): 547–60. http://dx.doi.org/10.1108/imds-07-2018-0287.

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PurposeConfirmations are applied in kit preparation for mixed-model assembly to promote quality, but research that explains the impact on time efficiency has been lacking. The purpose of this paper is to determine the extent to which the type of confirmation method relates to time-efficient kit preparation when order batching is applied.Design/methodology/approachAn industrially relevant laboratory experiment is applied, simulating kit preparation with order batching for mixed-model assembly. The time efficiency is studied as associated with four confirmation methods – barcode ring scanner, bu
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Syofi'i, Imam, Dendy Adanta, Aji Putro Prakoso, and Dewi Puspita Sari. "Application of Computational Fluid Dynamics Method for Cross-flow Turbine in Pico Scale." Journal of Energy Mechanical Material and Manufacturing Engineering 6, no. 1 (2021): 1–8. http://dx.doi.org/10.22219/jemmme.v6i1.12813.

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Crisis electricity was a crucial issue in the rural area. Crossflow turbine (CFT) in pico in pico scale is the best option for electricity provider for rural areas. Due to its usefulness and development of computer technology, computational fluid dynamics method application for CFT study becomes increasingly frequent. This paper compiles the implementation of the computational fluid dynamic (CFD) approach for CFT on a pico scale. Based on the literature, the Renormalization Group (RNG) turbulence model is recommended to predict the flow field that occurs in CFT because its error is lower than
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Oud, M. S., B. J. Houston, L. Volozonoka, et al. "Exome sequencing reveals variants in known and novel candidate genes for severe sperm motility disorders." Human Reproduction 36, no. 9 (2021): 2597–611. http://dx.doi.org/10.1093/humrep/deab099.

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Abstract STUDY QUESTION What are the causative genetic variants in patients with male infertility due to severe sperm motility disorders? SUMMARY ANSWER We identified high confidence disease-causing variants in multiple genes previously associated with severe sperm motility disorders in 10 out of 21 patients (48%) and variants in novel candidate genes in seven additional patients (33%). WHAT IS KNOWN ALREADY Severe sperm motility disorders are a form of male infertility characterised by immotile sperm often in combination with a spectrum of structural abnormalities of the sperm flagellum that
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Liu, Chunsheng, Chunping Ren, and Nengjian Wang. "Load Identification Method Based on Interval Analysis and Tikhonov Regularization and Its Application." Journal of Electrical and Computer Engineering 2019 (July 17, 2019): 1–8. http://dx.doi.org/10.1155/2019/1985025.

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In order to study the dynamic force identification method of an end-plate pick of shearer, a dynamic force identification technique based on interval theory was proposed. The dynamic force interval identification model is established by describing and quantifying the identified parameters. By using the interval analysis method of the first-order Taylor expansion, the dynamic force identification is transformed into two kinds of deterministic inverse problems at the midpoint of the uncertain parameter and its gradient identification. The Tikhonov regularization method is used to solve two kinds
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Pesicek, Jeremy D., Duncan Child, Brad Artman, and Konrad Cieślik. "Picking versus stacking in a modern microearthquake location: Comparison of results from a surface passive seismic monitoring array in Oklahoma." GEOPHYSICS 79, no. 6 (2014): KS61—KS68. http://dx.doi.org/10.1190/geo2013-0404.1.

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We present location results for a group of [Formula: see text] microearthquakes that occurred in 2012 in a region of Oklahoma hosting ongoing exploration activities. Using a local passive surface seismic monitoring network of 15 broadband stations, we applied two modern location techniques that use fundamentally different approaches. The first is a pick-based double-difference relocation method with waveform crosscorrelation. Multiple-event location techniques such as these are generally regarded as the best approach for obtaining high-precision locations from pick data. The second approach is
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Dawson, Robert B. "PICC Zone Insertion Method™ (ZIM™): A Systematic Approach to Determine the Ideal Insertion Site for PICCs in the Upper Arm." Journal of the Association for Vascular Access 16, no. 3 (2011): 156–65. http://dx.doi.org/10.2309/java.16-3-5.

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Abstract The consequences of random PICC practice can be serious and manifest as deep vein thrombosis, pulmonary embolism, catheter related bloodstream infection, and post thrombotic syndrome. Risk factors related to site selection have been well established for other central venous access devices, but not for ultrasound guided PICC insertion in the upper arm. The author presents observations of upper arm PICC insertion designated by color zones to highlight the variability of PICC practice. The author also details site risk factors associated with each color zone and proposes an ideal inserti
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