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Journal articles on the topic 'Pilomatricoma'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

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1

Harsha, Muvva Sri, Rajesh Goud E., and Srikanth Jakkula. "Benign proliferative pilomatricoma over sternum: a rare case." International Surgery Journal 5, no. 7 (2018): 2657. http://dx.doi.org/10.18203/2349-2902.isj20182792.

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Pilomatricoma is a benign, uncommon, subcutaneous tumor arising from the outer root sheath cell or hair matrix cells. Pilomatrixoma, benign calcifying epithelioma of Malherbe, trichomatricoma are synonyms for pilomatricoma. They occur mostly on head, neck and upper limb extremities. Histologically they classically consist of peripheral basiloid cells and central enucleated ghost or shadow cells. Malignant changes are rare in pilomatricomas. However, the proliferative variety is aggressive and considered to be precursor of malignancy. Here we present a case of benign proliferative pilomatricoma

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2

Eng, Renee K., Ahmed Shehabeldin, Megan Ketcham, Parul Shah, Seema Mullick, and Jae Y. Ro. "Multiple pilomatricomas: Recurrent skin nodules in myotonic dystrophy." Case Reports in Clinical Pathology 7, no. 1 (2020): 34. http://dx.doi.org/10.5430/crcp.v7n1p34.

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Pilomatricoma is a relatively uncommon benign tumor derived from the matrix of hair follicles. Multiple pilomatricomas may arise sporadically or in association with other disease entities. These entities include myotonic dystrophy type-1, a multisystem disorder that confers increased susceptibility to developing neoplasms, as well as familial adenomatous polyposis-related syndromes (including Gardner syndrome) and others. Here we present two case reports of multiple pilomatricomas that were initially misidentified clinically. We discuss pilomatricoma as a differential diagnosis of multiple ski

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3

Chessa, Marco Adriano, Maria Francesca Baracca, Alice Nadia Rossi, et al. "Pilomatricoma: Clinical, Dermoscopic Findings and Management in 55 Pediatric Patients and Concise Review of the Literature With Special Emphasis on Dermoscopy." Dermatology Practical & Conceptual 14, no. 2 (2024): e2024140. http://dx.doi.org/10.5826/dpc.1402a140.

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Introduction: Pilomatricoma is a benign adnexal dermal or subcutaneous tumor derived from immature hair matrix cells. Objectives: The aim of our study is to evaluate clinical and dermoscopic features of pilomatricomas, with a specific focus on pediatric lesions, and to provide a concise review of the existing literature. Methods: A single-center retrospective study was undertaken on 55 patients with a histopathological diagnosis of pilomatricoma referred to the Dermatology Unit, University of Bologna, Bologna, Italy, between 2005 and 2023. Pilomatricomas were retrospectively evaluated relying

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4

Bouabdella, Sara, Afaf Khouna, Siham Dikhaye, and Nada Zizi. "Isolated pilomatricoma of the arm: A case and a review of the literature." Our Dermatology Online 13, no. 1 (2022): 86–88. http://dx.doi.org/10.7241/ourd.20221.21.

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Pilomatricoma is a relatively rare tumor of the skin derived from primitive basal cells of the epidermis that differentiate into hair matrix cells. These tumors appear as solitary, firm nodules, showing a normal to pearl white epidermis. Its most frequent locations are the head and neck, while involvement of the upper extremities is relatively uncommon. Herein, we present the case of a seventeen-year-old female with pilomatricoma of the arm and review the literature regarding pilomatricomas of the upper extremities. The diagnosis of pilomatricoma is confirmed histologically and its treatment i

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5

Chakrabarti, Indranil. "Ossifying pilomatricoma: A rare entity." IP Archives of Cytology and Histopathology Research 7, no. 3 (2022): 202–4. http://dx.doi.org/10.18231/j.achr.2022.045.

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Pilomatricomas are rare benign skin adnexal tumors usually occurring in the head, neck or upper extremities of children and young adults. Ossifying pilomatricoma is a still rarer entity. Here, a case of a 22-year-old lady is reported, who presented with a firm to hard swelling in the right side of the neck. Histopathological examination of the resected specimen showed features of ossifying pilomatricoma with the formation of bone marrow elements. The patient was free of recurrence on 6-month follow-up. The case highlights a rare entity with characteristic histopathological features.

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6

D, Yogesh, Rashmi R. Mallya, Zigu S. Krishn, and K. Yashwanth Reddy. "Multiple malherbe’s calcifying epithelioma: A case report." IP Indian Journal of Clinical and Experimental Dermatology 8, no. 2 (2022): 135–37. http://dx.doi.org/10.18231/j.ijced.2022.029.

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Pilomatricoma, is an appendageal tumour of the skin usually seen in head and neck area. They are usually solitary, derived from the ectoderm and arise from the outer root sheath cells of the hair follicle. Multiple pilomatricomas are rare. We present a case of multiple pilomatricomas over the arm of a 13 year old girl.

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7

Sparling, Kennedy, and Christina Harview. "Pilomatricoma on the Abdomen with Overlying Striae Distensae: A Unique Presentation." SKIN The Journal of Cutaneous Medicine 8, no. 1 (2024): 1287–90. http://dx.doi.org/10.25251/skin.8.1.12.

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Pilomatricomas are benign neoplasms of the hair follicle. Alterations in the skin overlying pilomatricomas are rarely reported, and there are no reports with overlying striae distensae. We present an unusual case of pilomatricoma with overlying striae distensae on the flank of a young man and report its clinical findings. Recognition of this unique presentation of pilomatricomas is important for timely diagnosis and improved patient care, as these lesions have the potential for malignant transformation into pilomatrix carcinoma.

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8

Cavalcante, Mateus Barros, Éwerton Daniel Rocha Rodrigues, Caio Pimenteira Uchôa, et al. "Abordagem cirúrgica de pilomatricoma – relato de caso." Research, Society and Development 9, no. 10 (2020): e839108244. http://dx.doi.org/10.33448/rsd-v9i10.8244.

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Pilomatricoma ou epitelioma calcificante de Malherbe é uma neoplasia cutânea benigna rara, com origem nas células da matriz do folículo piloso que surge na maioria dos casos durante a infância ou adolescência. Clinicamente apresentam-se frequentemente como nódulos assintomáticos, com coloração geralmente semelhante à pele normal, localizados predominantemente na cabeça, pescoço ou extremidades superiores, de consistência habitualmente dura, crescimento lento e na maioria dos casos solitárias. A excisão cirúrgica é geralmente recomendada para os pilomatricomas, para prevenir o seu crescimento o

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9

Yasin, Rafeya, Sameen Afzal, Ghazi Zafar, and Samina Zaman. "Pilomatricoma with extensive ossification and marrow formation: a case report and review of literature." Pakistan Journal of Pathology 36, no. 1 (2025): 63–65. https://doi.org/10.55629/pakjpathol.v36i1.828.

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Pilomatricomas are follicular cystic neoplasms involving the dermis and subcutaneous tissue and have a benign behavior. Clinically they may present as hard papules or nodules. Histologically, they comprise of mummified cells, fibrillary bodies and trichohyaline granules. Excision is usually curative. Here we present a case of female patient with a lesion on back that turned out to be pilomatricoma but with extensive ossification.

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10

Leblebici, Cem, Begüm Yeni, Ozan Erdem, Ayşe Esra Koku Aksu, Erol Rüştü Bozkurt, and Cuyan Demirkesen. "Superficial variant of pilomatricoma, so‐called pilomatricomal horn." Journal of Cutaneous Pathology 46, no. 11 (2019): 801–4. http://dx.doi.org/10.1111/cup.13495.

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11

Charalsawadi, Chariyawan, Sasipong Trongnit, Kanoot Jaruthamsophon, et al. "No Evidence of Abnormal Expression of Beta-Catenin and Bcl-2 Proteins in Pilomatricoma as One Clinical Feature of Tetrasomy 9p Syndrome." International Journal of Pediatrics 2021 (December 15, 2021): 1–8. http://dx.doi.org/10.1155/2021/2612846.

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Background. Little is currently known about the genetics of pilomatricoma. A number of studies have reported some evidence that this disease may have a genetic association with mutations of CTNNB1 gene or expression of the beta-catenin protein. In this study, we reviewed literatures involving 30 patients with various genetic syndromes that have been linked to pilomatricoma and found that somatic mutations of the CTNNB1 gene were reported in 67% of patients. Pilomatricoma has been reported in patients with chromosome 9 rearrangements, including 4 patients with tetrasomy 9p syndrome and one pati

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12

Hsieh, Tsyh-Jyi, Chien-Kuo Wang, Kun-Bow Tsai, and Yu-Wen Chen. "Pilomatricoma." Journal of Computer Assisted Tomography 32, no. 2 (2008): 320–23. http://dx.doi.org/10.1097/rct.0b013e3180ca77ff.

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13

Barco, Leonardo, Clara Iglesias, and Inés Gonzalo. "Pilomatricoma." Piel 16, no. 8 (2001): 340–43. http://dx.doi.org/10.1016/s0213-9251(01)72487-2.

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14

Thompson, Lester D. R. "Pilomatricoma." Ear, Nose & Throat Journal 91, no. 1 (2012): 18–20. http://dx.doi.org/10.1177/014556131209100106.

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15

Sakai, Atsuko, Yu Maruyama, and Akiteru Hayashi. "Proliferating pilomatricoma: a subset of pilomatricoma." Journal of Plastic, Reconstructive & Aesthetic Surgery 61, no. 7 (2008): 811–14. http://dx.doi.org/10.1016/j.bjps.2007.02.013.

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16

Won, Seongjun, Ki Ju Cho, Somi Ryu, Ji-Hyun Seo, Jong Sil Lee, and Jung Je Park. "Evaluation of Ultrasonography and CT for Imaging of Head and Neck Pilomatricoma in Children and Adolescents." Korean Journal of Otorhinolaryngology-Head and Neck Surgery 64, no. 12 (2021): 922–27. http://dx.doi.org/10.3342/kjorl-hns.2021.00381.

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Background and Objectives Pilomatricoma is a frequently diagnosed skin lesion of the head and neck that may often be misdiagnosed as other skin lesions. This study evaluated whether ultrasonography (USG) or computed tomography (CT) is the most helpful imaging modality for the accurate preoperative diagnosis of pilomatricoma in head and neck regions of children and adolescents.Subjects and Method A retrospective review was conducted for 59 patients with pilomatricoma under the age of 19 years. All cases were pathologically confirmed with pilomatricoma in the head or neck.Results Preoperative im

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17

HORIUCHI, Yasuhiro, Kazunobu OTOYAMA, and Atsushi ITOH. "Malignant pilomatricoma." Nishi Nihon Hifuka 51, no. 5 (1989): 906–8. http://dx.doi.org/10.2336/nishinihonhifu.51.906.

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18

AO, Masakazu, Okiharu MAE, and You NAGASE. "Malignant pilomatricoma." Nishi Nihon Hifuka 52, no. 1 (1990): 54–59. http://dx.doi.org/10.2336/nishinihonhifu.52.54.

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19

Ozkaya, Dilek Biyik, Ozlem Su, Banu Taskin, Betul Tas, Mehmet Sar, and Nahide Onsun. "Bullous pilomatricoma." European Journal of Dermatology 23, no. 1 (2013): 104–5. http://dx.doi.org/10.1684/ejd.2012.1886.

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20

Niiyama, Shiro, Yasuyuki Amoh, Norimitsu Saito, Hiroshi Takasu, and Kensei Katsuoka. "Proliferating pilomatricoma." European Journal of Dermatology 19, no. 2 (2009): 188–89. http://dx.doi.org/10.1684/ejd.2008.0610.

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21

Uchiyama, N., Y. Shindo, and T. Saida. "Perforating pilomatricoma." Journal of Cutaneous Pathology 13, no. 4 (1986): 312–18. http://dx.doi.org/10.1111/j.1600-0560.1986.tb01528.x.

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22

Zulaica, A., C. Peteiro, C. Quintas, M. Pereiro, and J. Toribio. "Perforating pilomatricoma." Journal of Cutaneous Pathology 15, no. 6 (1988): 409–11. http://dx.doi.org/10.1111/j.1600-0560.1988.tb00575.x.

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23

Kaddu, Steven, H. Peter Soyer, Ingrid H. Wolf, and Helmut Kerl. "Proliferating pilomatricoma." Journal of Cutaneous Pathology 24, no. 4 (1997): 228–34. http://dx.doi.org/10.1111/j.1600-0560.1997.tb01586.x.

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24

Alli, Nuran, Emel Gu¨ngo¨r, and Ferda Artu¨z. "Perforating pilomatricoma." Journal of the American Academy of Dermatology 35, no. 1 (1996): 116–18. http://dx.doi.org/10.1016/s0190-9622(96)90523-x.

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25

Monteagudo Sánchez, B., E. León Muiños, C. Durana, J. M. Cacharrón Carreira, and C. de las Heras Sotos. "Pilomatricoma anetodérmico." Anales de Pediatría 64, no. 2 (2006): 181–82. http://dx.doi.org/10.1157/13084187.

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26

Taaffe, A., E. H. Wyatt, and H. P. R. Bury. "Pilomatricoma (Malherbe)." International Journal of Dermatology 27, no. 7 (1988): 477–80. http://dx.doi.org/10.1111/j.1365-4362.1988.tb00924.x.

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27

Nakayama, H., M. Mihara, and S. Shimao. "Acantholytic Pilomatricoma." Dermatology 181, no. 4 (1990): 314–16. http://dx.doi.org/10.1159/000247836.

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28

Lozzi, Gian Piero, H. Peter Soyer, Julia Fruehauf, Cesare Massone, Helmut Kerl, and Ketty Peris. "Giant Pilomatricoma." American Journal of Dermatopathology 29, no. 3 (2007): 286–89. http://dx.doi.org/10.1097/dad.0b013e318053db45.

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29

Byun, Ji-Won, Chan-Yl Bang, Bo-Hee Yang, et al. "Proliferating Pilomatricoma." American Journal of Dermatopathology 33, no. 7 (2011): 754–55. http://dx.doi.org/10.1097/dad.0b013e31820a1d47.

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30

Li, Li, Yueping Zeng, Kai Fang, et al. "Anetodermic Pilomatricoma." American Journal of Dermatopathology 34, no. 4 (2012): e41-e45. http://dx.doi.org/10.1097/dad.0b013e31823583f5.

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31

Carretero Hernández, Gregorio, María del Pino Rivero Suárez, Pilar de la Rosa Rey, and Paloma Santamaría Blanco. "Pilomatricoma pigmentado." Actas Dermo-Sifiliográficas 93, no. 9 (2002): 558–60. http://dx.doi.org/10.1016/s0001-7310(02)76639-8.

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32

Li, Yu-Rong, Kai-Jen Lin, and Tun-Yen Hsu. "Auricle Pilomatricoma." Journal of Pediatrics 158, no. 3 (2011): 511–511. http://dx.doi.org/10.1016/j.jpeds.2010.09.064.

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33

Ratnayake, R. M. P., R. L. P. R. Liyanage, and I. K. Rambukwella. "Pilomatricoma revisited." Journal of Diagnostic Pathology 6, no. 1 (2012): 12. http://dx.doi.org/10.4038/jdp.v6i1.4417.

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34

de Souza, Elemir M., Andrelou F. Ayres Vallarelli, Maria L. Cintra, Claudia-S. Vetter-Kauczok, and Eva-B. Brocker. "Anetodermic pilomatricoma." Journal of Cutaneous Pathology 36, no. 1 (2009): 67–70. http://dx.doi.org/10.1111/j.1600-0560.2008.01008.x.

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35

Tay, Yong‐Kwang. "Exophytic pilomatricoma." Pediatric Dermatology 20, no. 4 (2003): 373. http://dx.doi.org/10.1046/j.1525-1470.2003.20326_4.x.

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36

Fujiwara, Takashi, Hiroshi Yamamoto, and Makoto Hashiro. "Malignant pilomatricoma." Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 36, no. 2 (2002): 119–21. http://dx.doi.org/10.1080/028443102753575310.

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37

Gund, Tapasaya, Rahul A. Telang, Kireet Yathati, and Prakhar Kumar. "Exceptionally rare site:the occurrence of pilomatricoma of the ear lobule." International Journal of Otorhinolaryngology and Head and Neck Surgery 10, no. 5 (2024): 584–87. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20242719.

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Pilomatricoma, a rare benign tumor primarily affecting the head and neck region, presents diagnostic challenges and requires histopathological confirmation for accurate diagnosis. A case of pilomatricoma in a 70-year-old female with a chronic swelling on the Left ear lobule is reported. Surgical excision was performed, confirming the diagnosis histopathologically, highlighting the importance of accurate recognition and management. Timely surgical excision of pilomatricoma is crucial, with low recurrence rates reported. Accurate diagnosis aids in appropriate management and optimal patient outco

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38

Erkayman, Merve Hatun, Melike Güven, Merve Bingöl, Numan Bulut, and Rabia Demirtaş. "Pilomatricoma Growing at the SARS-CoV-2 mRNA Vaccination Site." Indian Journal of Dermatology 68, no. 5 (2023): 588. http://dx.doi.org/10.4103/ijd.ijd_409_23.

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A healthy 21-year-old woman was presented to our outpatient clinic with an asymptomatic swelling on her left arm. She reported the administration of two doses of BNT162b2 mRNA vaccination at the lesion site earlier. The pathology report confirmed the diagnosis of pilomatricoma. Previously, needlestick trauma and various immunisations have been attributed to the development of pilomatricoma. We present this case to emphasise the possible association between BNT162b2 mRNA vaccination and pilomatricoma development. The role of persistent inflammation is also discussed.

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39

Xin, Tan Ying, Jeyasakthy Saniasiaya, Jeyanthi Kulasegarah, and Chiew Seow Fan. "Commonly Misdiagnosed Facial Lesion: Pilomatricoma." Acta Medica (Hradec Kralove, Czech Republic) 66, no. 4 (2023): 158–60. http://dx.doi.org/10.14712/18059694.2024.11.

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Pilomatricoma, also known as Pilamatrixoma or Malherbe’s calcifying epithelioma, is a benign skin tumour with a bimodal age distribution between the paediatric and elderly age groups. Although it was previously thought to be rare, recent studies have revealed that it is quite common. Typically, pilomatricoma is diagnosed following histopathological examination of the lesion as it is frequently misdiagnosed with other types of skin pathology. In our case, the child presented with painless swelling of the left infraauricular region. The initial cytology and imaging were unable to provide a defin

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40

Ghartimagar, D., A. Ghosh, K. Gautam, S. Thapa, SR Shrestha, and R. Narasimhan. "Clinicopathological features of pilomatricoma cases: Analysis of 21 cases." Journal of Pathology of Nepal 4, no. 7 (2014): 530–33. http://dx.doi.org/10.3126/jpn.v4i7.10293.

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Background: Pilomatricoma is a slow-growing, asymptomatic tumour originating from outer sheath cells of hair follicle. In this study, we describe the clinical presentation and histopathological features of pilomatricoma. Materials and Methods: This was a hospital based retrospective study carried out in all patients who were diagnosed as pilomatricoma over a period of January 2001 to December 2013. The study was done in department of pathology, Manipal Teaching Hospital, Nepal. Results: A total of 21 cases of pilomatricoma were reported with age range of 9-53 years (mean age 23.7) and male fem

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41

Lim, Seok Beom, In Chang Koh, Hoon Kim, Kun Young Kwon, and Soo Yeon Lim. "Pigmented Pilomatricoma on the Ear Resembling Vascular Tumor before Surgery: A Case Report." Korean Society for Head and Neck Oncology 39, no. 2 (2023): 31–34. http://dx.doi.org/10.21593/kjhno/2023.39.2.31.

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Pilomatricoma is characterized by a semi-transparent epidermis, especially pigmented pilomatricoma, containing melanocytes in basaloid cells, which are dark and purple, resembling vessel-derived skin masses. If the vascularity at doppler ultrasound is high before surgery, it may be misdiagnosed.A 10-year-old female patient visited our clinic because of a mass in the right ear triangular fossa. Ultrasonography was performed, and a vascular-origin tumor was suspected because of the high vascularity. The excised mass was diagnosed as pigmented pilomatricoma by a pathologist.Pilomatricoma is mista

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42

Chakiri, Radia, and Youssef Bouhajeb. "Dermoscopy of pilomatricoma: A case report with a review of the literature." Our Dermatology Online 13, no. 1 (2022): 82–85. http://dx.doi.org/10.7241/ourd.20221.20.

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Pilomatricoma is a benign tumor originating from hair follicle matrix cells and characterized by the presence of cutaneous and subcutaneous nodules up to 3.0 cm in diameter, usually on the head, neck, and upper extremities, rarely on the trunk and lower extremities. An eleven-year-old female with a painless, erythematous-purplish tumor of the back. A dermoscopic examination revealed irregular linear vessels, white structures, and structureless grayish-blue areas. Histological examination after excision confirmed the diagnosis of pilomatricoma. Dermoscopy may be a useful tool for improving the

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43

Radovanovic-Bobic, Anica, and Zoran Latkovic. "Pilomatrikom kao oftalmohirurski problem." Acta chirurgica Iugoslavica 50, no. 4 (2003): 135–37. http://dx.doi.org/10.2298/aci0304134r.

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Pilomatricoma, relativly rare benign tumour of the hair matrix cells, is usually misdiagnosed preoperativly. This result in unnecessary extensive surgery. In order to improve diagnosis and treatment of pilomatricoma, autors discusse their ten years experience (28 cases) with this tumour.

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44

Weichert, Gabriele E., Kevin L. Bush, and Richard I. Crawford. "Bullous Pilomatricoma: A Report of Clinical and Pathologic Findings and Review of Dermal Bullous Disorders." Journal of Cutaneous Medicine and Surgery 5, no. 5 (2001): 394–96. http://dx.doi.org/10.1177/120347540100500504.

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Background: Pilomatricoma is a common benign adnexal tumor differentiating toward elements of the hair matrix and shaft. It typically presents as a solitary, deep, dermal nodule. We describe a case of a pilomatricoma with the unusual feature of a thick-walled dermal bulla overlying the tumor. Objective: We describe a case of bullous pilomatricoma and discuss the potential etiology of the bullous feature of the lesion. Methods: This article includes a case report and a literature review. Conclusions: Bullous pilomatricoma has rarely been described. A common pathological feature in this type of

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45

Sano, Y., M. Mihara, T. Miyamoto, and S. Shimao. "Simultaneous occurrence of calcification and amyloid deposit in pilomatricoma." Acta Dermato-Venereologica 70, no. 3 (1990): 256–59. http://dx.doi.org/10.2340/0001555570256259.

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Amyloid deposition was encountered in 10 of 16 samples of pilomatricoma, indicating that the deposition of amyloid is nearly as common as calcification in pilomatricoma. In addition, a simultaneous occurrence of calcification and amyloid deposit in pilomatricoma was recognized in 9 of 16 samples. The calcification and the deposition of amyloid developed topographically in the same area within the shadow cell masses. Such an area was revealed as moderately basophilic, amorphous, or hyalinized by H&E staining. Electron microscopy revealed spotty calcium deposits in amyloid. No light chains o

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46

OBATA, Chikage, Hiromaro KIRYU, and Masahiro USHIJIMA. "Giant Pedunculated Pilomatricoma." Nishi Nihon Hifuka 61, no. 5 (1999): 606–8. http://dx.doi.org/10.2336/nishinihonhifu.61.606.

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47

Kim, Dong Hun, Kyu Sung Cho, and Do Hyun Kim. "Pilomatricoma: Case Report." Journal of the Korean Radiological Society 48, no. 2 (2003): 189. http://dx.doi.org/10.3348/jkrs.2003.48.2.189.

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48

UCHIMIYA, Hiroshi, Takuro KANEKURA, Akiyo GUSHI, Seita FUKUMARU, Yasutada BABA, and Tamotsu KANZAKI. "Multiple giant pilomatricoma." Journal of Dermatology 33, no. 9 (2006): 644–45. http://dx.doi.org/10.1111/j.1346-8138.2006.00151.x.

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49

Garioni, E., G. M. Danesino, and L. Madonia. "Pilomatricoma: Sonographic features." Journal of Ultrasound 11, no. 2 (2008): 76–78. http://dx.doi.org/10.1016/j.jus.2008.03.001.

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50

Gati, Carolina Alves Dos Reis, Paulo de Camargo Moraes, Victor Montalli, et al. "Pilomatricoma: case report." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139, no. 5 (2025): e32. https://doi.org/10.1016/j.oooo.2025.01.164.

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