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Dissertations / Theses on the topic 'PIP5K1'

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1

黒田, 凌. "シロイヌナズナにおけるPIP5K7,PIP5K8およびPIP5K9の機能解析". Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/264646.

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2

Gonzales, Baptiste. "Etudes des facteurs cellulaires et lipidiques déterminant la localisation du site d'assemblage et de bourgeonnement du VIH-1." Electronic Thesis or Diss., Tours, 2019. http://www.theses.fr/2019TOUR3811.

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La formation des particules du VIH-1 résulte de l'assemblage des précurseurs Gag sur le feuillet interne de la membrane plasmique (MP) des cellules infectées. Les protéines Gag sont spécifiquement adressées à la MP grâce à des interactions entre le domaine MA et le PI(4,5)P2. Cette étude décrit le rôle des phosphadidylinosito1-4-phosphate 5-kinase de type 1 (PIP5K1alpha, beta et sigma) au cours des étapes tardives du VIH-1 dans le modèle celllulaire HeLa. Nous avons démontré que la PIP5K1alpha est l'enzyme principalement impliquée dans la production du PI(4,5P2. En suivant le trafic de Gag à l
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3

Liu, Chen [Verfasser], and Anton [Akademischer Betreuer] Schäffner. "The PIP1 protein expression is positively regulated by PIP2;1 and PIP2;2 in Arabidopsis thaliana / Chen Liu. Betreuer: Anton Schäffner." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1078852243/34.

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4

Champeyroux, Chloé. "Caractérisation fonctionnelle de protéines en interaction avec l'aquaporine PIP2;1." Thesis, Montpellier, 2017. http://www.theses.fr/2017MONTT120.

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La conductivité hydraulique racinaire (Lpr) traduit la capacité de transport d’eau de la racine. Lors de son trajet du sol vers le xylème, l’eau diffuse au sein de l’apoplasme ou au travers des cellules (voie de cellule-à-cellule). Au niveau de l’endoderme, la diffusion apoplasmique de l’eau est bloquée par le cadre de Caspari et des lamelles de subérine. La voie de cellule-à-cellule dépend principalement de l’activité des aquaporines régulées en partie par des interactions protéiques. Ce travail caractérise de nouveaux interactants de l’aquaporine racinaire PIP2;1 : le récepteur kinase RKL1 e
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5

Kurenbach, Brigitta. "Konjugativer DNA-Transfer zwischen Gram-positiven und Gram-negativen Spezies: Transferkomponenten des Multiresistenzplasmids pIP501 aus Streptococcus agalactiae." [S.l.] : [s.n.], 2004. http://deposit.ddb.de/cgi-bin/dokserv?idn=971485305.

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6

Toscano, Sarah. "Functional characterisation of PIP4K in Drosophila melanogaster." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609822.

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7

Tavelis, Christodoulos. "Investigating the potential role of PIP4Ks in PI3K/Akt signalling." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/investigating-the-potential-role-of-pip4ks-in-pi3kakt-signalling(e70d9473-5932-468a-bdad-01668a68db58).html.

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Class I phosphoinositide 3-kinases (PI3Ks) generate the essential lipid second messenger PtdIns(3,4,5)P3 which plays a key role in the regulation of numerous cellular processes including cell growth and survival, gene transcription, cytoskeletal organisation and glucose metabolism through its downstream effectors and in particular the serine/threonine protein kinase Akt. Therefore, the PI3K/Akt signalling plays a critical regulatory role in diverse cellular processes and its dysregulation is implicated in the pathogenesis of many human diseases including cancer and type 2 diabetes. Overexpress
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8

Jouette, Julie. "Phosphoinositides et contrôle de la polarité cellulaire : régulations croisées entre la PIP5K Skittles et les protéines de polarité PAR1 et PAR3." Thesis, Sorbonne Paris Cité, 2017. http://www.theses.fr/2017USPCC118.

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La polarité cellulaire est un processus fondamental qui contrôle les spécificités fonctionnelle et physiologique de la plupart des cellules eucaryotes. Cette asymétrie intracellulaire repose sur l’existence de compartiments membranaires distincts, à la fois dans leur composition en protéines mais également en phosphatidyl-inositols (PIs). Ainsi, la mise en place et le maintien de la localisation asymétrique de modules multi-protéiques associés notamment aux protéines PAR sont essentiels pour l’élaboration des domaines de polarité cellulaire. Durant ma thèse, j’ai étudié les relations entre les
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9

Gerth, Angela Katharina [Verfasser]. "Phosphoinositide im Kern pflanzlicher Zellen : Kernlokalisierung der ubiquitären PI4P 5-Kinase PIP5K2 und ihr Einfluss auf die Entwicklung von Arabidopsis thaliana / Angela Katharina Gerth." Halle, 2018. http://d-nb.info/1155760921/34.

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10

Othman, Arige. "Pharmacomodulation on the piperidinol skeleton: Synthesis of novel PIPD1 derivatives as Mycobacterium abscessus agents." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13396/.

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Mycobacterium abscessus (M. abscessus) is a rapidly growing mycobacterium which is able to generate different problems in human infections, such as chronic lung diseases, pulmonary diseases and skin infection. M. abscessus is considered as the first emergent opportunistic pathogen and the number of the infections due to this pathogen increases each year. Since the natural multidrug resistance and the absence of specific treatment to fight it, M. abscessus has become a serious problem of the public health. In this context, an original approach of a phenotypic screen was performed and allowed to
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11

和田, 悠貴香. "リン酸欠乏に応答した根毛伸長におけるシロイヌナズナのPIP5K遺伝子の機能解析". 京都大学 (Kyoto University), 2015. http://hdl.handle.net/2433/199149.

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12

Xia, Yang. "The localisation and regulation of phosphatidylinositol-4-phosphate 5-Kinase gamma splice variants and the discovery of a new mammalian splice variant, PIP5KIγ_v6". Thesis, University of Cambridge, 2011. https://www.repository.cam.ac.uk/handle/1810/240633.

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Type I PIP kinases (phosphatidylinositol 4-phosphate 5-kinases, PIP5Ks) catalyse the majority of cellular synthesis of PI(4,5)P2. To date, three mammalian isoforms (r1, r2, r3) have been found. PIP5KIr is subject to complex C-terminal splice variation, enhancing its transcriptional diversity through evolution and producing at least 5 known spliceoforms in the mammals. This study addresses several important questions. (1) Several remarkable differences have been discovered between the neuronal splice variant PIP5KIr_i3 and its close variant, Ir_i2, whose peptide lacks a 26-AA insert near its C-
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13

Kopec, Jolanta. "Structure analysis of DNA relaxases, the key enzymes of bacterial conjugation traA and its N-terminal relaxase domain of the Gram-positive plasmid pIP501 show specific oriT binding and behave as dimers in solution /." [S.l.] : [s.n.], 2006. http://deposit.ddb.de/cgi-bin/dokserv?idn=981331483.

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14

Alves, Rui Jorge Andrade. "Role of PIP5K in heat-stress signalling and tolerance in Arabidopsis thaliana." Master's thesis, 2018. http://hdl.handle.net/1822/59485.

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Dissertação de mestrado em Plant Molecular Biology, Biotechnology and Bioentrepreneurship<br>Plants are exposed to a wide variety of biotic and abiotic stresses that disturb their development and productivity, such as extreme temperatures that can gravely affect the plant morphology, physiology and metabolism. On its turn, plants have developed responses to cope with heat stress, a process termed thermotolerance. Basal thermotolerance refers to the innate capacity of plants to survive when exposed to high temperatures while acquired thermotolerance involves a prior acclimation to a modera
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15

Chen, Ling-Tzu, and 陳伶慈. "EZH2 Regulates Neuronal Differentiation of Human Mesenchymal Stem Cells through PIP5K1C-Dependent Calcium Signaling." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/88592703611820272542.

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碩士<br>亞洲大學<br>生物科技學系碩士班<br>98<br>Enhancer of zeste homolog 2 (EZH2), a polycomb group (PcG) protein, regulates stem cells renewal and differentiation. Phosphatidylinositol-4-phosphate 5-kinase, type I gamma (PIP5K1C) plays an important role in synthesis of phosphatidylinositol 4, 5-bisphosphate [PI(4,5)P2]. Phospholipase C (PLC) hydrolyzes PI(4,5)P2 into inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), in which IP3 is an intracellular messenger to activate calcium signaling. Change in intracellular calcium concentration is required and critical in neuronal differentiation. However,
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16

Kurenbach, Brigitta [Verfasser]. "Konjugativer DNA-Transfer zwischen Gram-positiven und Gram-negativen Spezies: Transferkomponenten des Multiresistenzplasmids pIP501 aus Streptococcus agalactiae / vorgelegt von Brigitta Kurenbach." 2004. http://d-nb.info/971485305/34.

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17

Abajy, Mohammad Yaser [Verfasser]. "Molekularbiologische und biochemische Untersuchungen zum Typ-IV-Sekretion-ähnlichen System (T4SLS) des konjugativen Antibiotikaresistenzplasmids pIP501 in Enterococcus faecalis / vorgelegt von Mohammad Yaser Abajy." 2007. http://d-nb.info/985309326/34.

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18

Arends, Karsten [Verfasser]. "Entwicklung von gfp-basierten Monitoring-Tools zur Verfolgung von horizontalem Gentransfer und Studien zum T4SLS des konjugativen Plasmids pIP501 aus Enterococcus faecalis / vorgelegt von Karsten Arends." 2010. http://d-nb.info/1013322037/34.

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19

Kopec, Jolanta [Verfasser]. "Structure analysis of DNA relaxases, the key enzymes of bacterial conjugation : traA and its N-terminal relaxase domain of the Gram-positive plasmid pIP501 show specific oriT binding and behave as dimers in solution / vorgelegt von Jolanta Kopec." 2006. http://d-nb.info/981331483/34.

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