Relevant bibliographies by topics / Piperidine and morpholine

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Piperidine and morpholine'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Piperidine and morpholine"

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Khamitova, A. E., and D. A. Berillo. "Overview of Piperidine and Morpholine Derivatives as Promising Sources of Biologically Active Compounds (Review)." Drug development & registration 12, no. 2 (2023): 44–54. http://dx.doi.org/10.33380/2305-2066-2023-12-2-44-54.

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Introduction. The search for new, effective and safe pharmacologically active substances remains an urgent task in the field of pharmacy. Many compounds of the piperidine and morpholine series are widely used in medical practice and belong to an important group of biologically active compounds. An informational, literature search on the synthesis of new derivatives of piperidine and morpholine was carried out. The article summarizes the results of studies of new derivatives of piperidine and morpholine as potential sources of biologically active substances.Text. The review is devoted to the re
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Petrov, Oleg A., and Irina N. Sadovskaya. "CATALYTIC ACTION OF NITROGEN-CONTAINING BASES ON KINETICS OF ZINC AND HEXA- (m-TRIFLUOROMETHYLPHENYL)BENZOPORPHYRAZINE COMPLEX FORMATION." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENIY KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 60, no. 3 (2017): 36. http://dx.doi.org/10.6060/tcct.2017603.5543.

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A complexation reaction of hexa(m-trifluoromethylphenyl)benzoporphyrazine with zinc acetate in the system “morpholine (piperidine) – benzene” was studied. Preliminary studies have shown that at concentrations of morpholine and piperidine in benzene less than 0.95 and 0.2 mol/l respectively, the reactions between hexa(m-trifluoromethylphenyl)benzoporphyrazine and zinc acetate not observed. The reaction takes place only at the range of concentrations of morpholine of 0.95 to 8.70 mol /l in benzene and at the range of concentrations of piperidine of 0.2 to 7.74 mol /l in benzene. The changes in t
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OLIVEIRA, MAILCAR F., TELMA L. G. LEMOS, MARCOS C. DE MATTOS, TACIANA A. SEGUNDO, GILVANDETE M. P. SANTIAGO, and RAIMUNDO BRAZ-FILHO. "New enamine derivatives of lapachol and biological activity." Anais da Academia Brasileira de Ciências 74, no. 2 (2002): 211–21. http://dx.doi.org/10.1590/s0001-37652002000200004.

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A convenient synthesis of the new enamine derivatives 2-(4-morpholinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione, 2-(1-piperidinyl)-3-(3-methyl-2-butenyl)-1,4-naphtalenedione and 2-(1-pyrrolidinyl)-3-(3-methyl-2-butenyl)-1,4-naphthalenedione was carried out from natural 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione (lapachol) and morpholine, piperidine and pyrrolidine. The structures of the products were established mainly by NMR analysis, including 2D experiments. Biological activities of these products were evaluated against Artemia salina, Aedes aegypti and cytotoxicity using A54
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P.Badiger, Naveen, and I. M. Khazi. "Synthesis & Evaluation of Antitubercular Activity of Novel Mannich Bases of imidazo[2,1-b][1,3,4]thiadiazoles." Advanced Materials Research 816-817 (September 2013): 1197–201. http://dx.doi.org/10.4028/www.scientific.net/amr.816-817.1197.

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A series of 2-(4-methoxybenzyl)-6-aryl-5-pyrrolidin/piperidin/morpholin-1-ylmethyl-imidazo [2,1-[1,3, thiadiazoles (3a-e, 4a-e & 5a-e) were synthesized by Mannich reaction by condensing 2-(4-methoxybenzyl)-6-arylimidazo [2,1-[1,3,thiadiazoles with pyrrolidine, piperidine and morpholine. The title compounds were screened for antitubercular activity againstMycobacterium tuberculosisH37Rv using the BACTEC 460 radiometric assay. Mannich bases with pyrrolidine substitution were found to be most active antitubercular agents. It proves that as the ring size decreases it becomes much potent in its
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Shalaby, ElSayed M., Aisha M. Moustafa, Adel S. Girgis, and Aida M. ElShaabiny. "Crystal Structures of Ethyl 4-(4-Florophenyl)-6-phenyl-2-substituted-3-pyridinecarboxylates." Journal of Crystallography 2014 (May 4, 2014): 1–7. http://dx.doi.org/10.1155/2014/148741.

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Three substituted pyridinecarboxylates were synthesized; (I) ethyl 2-bromo-4-4(fluorophenyl)-6-phenyl-3-pyridinecarboxylate, C20H15BrFNO2, (II) ethyl 4-(4-fluorophenyl)-2-(4-morpholinyl)-6-phenyl-3-pyridinecarboxylate, C24H23FN2O3, and (III) ethyl 4-(4-fluorophenyl)-6-phenyl-2-(1-piperidinyl)-3-pyridinecarboxylate, C25H25FN2O2. It was found that compound (I) belongs to the orthorhombic system with space group P212121, compound (II) to the monoclinic system with space group P21/c, and compound (III) to the monoclinic system with space group C2/c. The morpholine ring in (II) and piperidine ring
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Poupin, P., J. J. Godon, E. Zumstein, and N. Truffaut. "Degradation of morpholine, piperidine, and pyrrolidine by mycobacteria: evidences for the involvement of a cytochrome P450." Canadian Journal of Microbiology 45, no. 3 (1999): 209–16. http://dx.doi.org/10.1139/w99-002.

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Nine bacterial strains that grew on morpholine and pyrrolidine as sole carbon, nitrogen, and energy sources were isolated from three different environments with no known morpholine contamination. One of these strains could also degrade piperidine. These bacteria were identified as Mycobacterium strains. A phylogenetic analysis based on the partial 16S rDNA sequences indicated that the isolated strains clustered within the fast growing group of mycobacteria. When the above-mentioned cyclic amines were used as growth substrates, the synthesis of a soluble cytochrome P450 was induced in all these
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Modec, Barbara, Nina Podjed, and Nina Lah. "Beyond the Simple Copper(II) Coordination Chemistry with Quinaldinate and Secondary Amines." Molecules 25, no. 7 (2020): 1573. http://dx.doi.org/10.3390/molecules25071573.

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Copper(II) acetate has reacted in methanol with quinaldinic acid (quinoline-2-carboxylic acid) to form [Cu(quin)2(CH3OH)]∙CH3OH (1) (quin− = an anionic form of the acid) with quinaldinates bound in a bidentate chelating manner. In the air, complex 1 gives off methanol and binds water. The conversion was monitored by IR spectroscopy. The aqua complex has shown a facile substitution chemistry with alicyclic secondary amines, pyrrolidine (pyro), and morpholine (morph). trans-[Cu(quin)2(pyro)2] (2) and trans-[Cu(quin)2(morph)2] (4) were obtained in good yields. The morpholine system has produced a
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Yadav, Bodke, and S. Sangapure S. "Synthesis and biological activity of some benzofuro[3,2-d]pyrimidines." Journal of Indian Chemical Society Vol. 80, Mar 2003 (2003): 187–89. https://doi.org/10.5281/zenodo.5839259.

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Department of Studies and Research in Chemistry. Gulbarga University, Gulbarga-585 106, India <em>E-mail :</em> bodke___yd@rediffmail.com <em>Manuscript received 21 December 2001 .revised 18 April 2002, accepted 12 December 2002</em> The condensation of ethyl 3-amino-2-benzofuran carboxylate (1) with phenyl isocyanate gave 3-phenylureido-2-benzofuran carboxylate (2), which upon treatment&nbsp;with phosphorus oxychloride gave 2-chloro-3-phenyl-3,4-dihydro-4-oxohenzofnro[3,2-<em>d</em>]pyrimidine (4). The reaction of 4 with alicyclic amines like piperidine and morpholine yielded 2-piperidino/mor
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Parkin, Andrew, Iain D. H. Oswald, and Simon Parsons. "Structures of piperazine, piperidine and morpholine." Acta Crystallographica Section B Structural Science 60, no. 2 (2004): 219–27. http://dx.doi.org/10.1107/s0108768104003672.

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The crystal structures of piperazine, piperidine and morpholine have been determined at 150 K. All three structures are characterized by the formation of NH...N hydrogen-bonded chains. In piperazine these are linked to form sheets, but the chains are shifted so that the molecules interleave. In morpholine there are in addition weak CH...O interactions. Topological analyses show that these three structures are closely related to that of cyclohexane-II, which can be described in terms of a pseudo-cubic close-packed array of molecules in a familiar ABC layered arrangement. While the positions of
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CHAITANYA, G. DAVE, R. SHAH P., S. PANDYA P., and K. SHAH G. "Pyridopyrimidines. Part-VII. Synthesis and Antibacterial Activity of 4-lminopyrido[2, 3 - d] pyrimidin- 2( 1 H)-thiones, 2-Thioxopyrido[2, 3 - d]pyrimidin-4(3H)-ones and related Compounds." Journal of Indian Chemical Society Vol. 66, Nov 1989 (1989): 810–12. https://doi.org/10.5281/zenodo.6106035.

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Department of Chemistry, St. Xavier&#39;s College, Navarangpura, Ahmedabad-380 009 <em>Manuscript received 27 December 1988, revised 23 June 1989, accepted 26 June 1989</em> 2-Amino-3-cyano-4-(4-chlorophenyl)-6-phenylpyridine (I) and 2-amino&middot;3&middot;carboxamido-4-(4-chlorophenyl)&middot;6-phenylpyridine (3) when reacted with various isothiocyanates, 4-amino-3&middot;substituted-5-(4&middot;chlorophenyl)-7&middot;phenylpyrido[2,3-<em>d</em>]pyrimidin-2(1<em>H</em>)-thiones(2) and 2&middot;thioxo-3-substituted-5-(4-chlorophenyl)-7-phenylpyrido[2,3-<em>d</em>]pyrimidin-4(3<em>H</em>)-ones
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Dissertations / Theses on the topic "Piperidine and morpholine"

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Zziwa, Miriam C. N. "Fungicide resistance to morpholine and piperidine fungicides in barley and wheat powdery mildew, Erysiphe graminis D.C." Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/27744.

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This work was carried out to study the sensitivity of barley and wheat powdery mildew (<I>Erysiphe graminis </I>f.sp. <I>hordei</I> and <I>E. graminis </I>f.sp. <I>tritici</I> respectively) to morpholine fungicides. Morpholine fungicides are classified as compounds with a low risk of resistance development. On the other hand, barley and wheat powdery mildews belong to the group of high risk fungi as far as development of fungicide resistance is concerned. Firstly, mildew isolates collected in the UK were assessed, over the period 1992 to 1995, for their sensitivity to three morpholine fungicid
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Silvestrini, Filippo. "A DFT study on chemodivergent preparation of piperidinic and morpholinic heterocycles." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amslaurea.unibo.it/20660/.

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The topic of this thesis is the DFT computational study of the mechanisms for the synthesis of chiral 3,4,5-trisubstituted piperidines and 2,6-disubstituted morpholines. The goal of this synthesis is to use, the same substrate containing two electrophilic sites: an α,β-unsaturated ester and a ketone, which evolve according to the nucleophile used (cyanide, phenyl sulfide) through different addition and cyclization reactions. A quaternary ammonium salt is used as a catalyst for these reactions, which leads to a diastereoisomeric excess both for the reactions of morpholine and piperidine product
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GHOBSI, MEBROUK. "Synthese d'heterocycles azotes satures (morpholines et piperidines multihydroxylees) enantiomeriquement pures a partir de lactones monosaccharidiques." Clermont-Ferrand 2, 1991. http://www.theses.fr/1991CLF21319.

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Un axe important de la chimie des glucides est leur transformation en des composes chiraux possedant des proprietes biologiques et des applications dans le domaine industriel. Notre objectif a ete la synthese de morpholines et de piperidines multihydroxylees enantiomeriquement pures. Deux series de morpholines fonctionnalisees et une piperidine hydroxylee ont ete preparees par synthese multistade a partir de lactones glucidiques aisement disponibles (d-ribonolactone, d-gulonolactone et d-isosaccharinolactone). Les reactions de protection selective des fonctions alcool d'une lactone glucidique
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Gruhn, Veit Joshua [Verfasser]. "Wirkungseffizienz von Fungiziden (Strobilurine, Triazole, Morpholine, Piperidine, Spiroketalamine) hinsichtlich Leistung und biologisch-epidemiologischer Effekte gegenüber pilzlichen Krankheitserregern in Winterweizen / vorgelegt von Veit Josua Gruhn." 2003. http://d-nb.info/971597081/34.

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Book chapters on the topic "Piperidine and morpholine"

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Raissi, Hanen, Imen Chérif, Hajer Ayachi, et al. "Structure-Property Relationships in Benzofurazan Derivatives: A Combined Experimental and DFT/TD-DFT Investigation." In Density Functional Theory - Recent Advances, New Perspectives and Applications [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99246.

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In this work we seek to understand and to quantify the reactivity of benzofurazan derivatives toward secondary cyclic amines, like pyrrolidine, piperidine and morpholine, acting as nucleophile groups in SNAr reactions. For this aim, physico-chemical and structural descriptors were determined experimentally and theoretically using the DFT/B3LYP/6-31+ g (d,p) methodology. Thus, different 4-X-7-nitrobenzofurazans (X = OCH3, OC6H5 and Cl) and products corresponding to the electrophilic aromatic substitution by pyrrolidine, piperidine and morpholine, were investigated. Particularly, the HOMO and LU
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Chartrain, Laetitia, and James K. M. Brown. "Molecular evolution and mechanisms of fungicide resistance in plant pathogenic fungi." In Understanding and minimising fungicide resistance. Burleigh Dodds Science Publishing, 2023. http://dx.doi.org/10.19103/as.2022.0116.02.

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Since the introduction in the late 1960s of systemic fungicides with modes of action involving inhibition of single target sites, resistance to many of these products has evolved in populations of fungal pathogens. Many important pathogens have developed reduced sensitivity to many of the major classes of systemic fungicide used in agriculture and horticulture. This chapter reviews mechanisms of resistance to the most widely-used, broad-spectrum groups of fungicide over the last 50 years, including methyl benzimidazole carbamate (MBC) fungicides, azoles, amines including morpholines and piperi
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Conference papers on the topic "Piperidine and morpholine"

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Sravya, G., N. Bakthavatchala Reddy, and Grigory V. Zyryanov. "Synthesis, structural elucidation and bioassay of morpholine/thiomorpholine and piperidine containing oxazoles." In PROCEEDINGS OF INTERNATIONAL CONFERENCE ON RECENT TRENDS IN MECHANICAL AND MATERIALS ENGINEERING: ICRTMME 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0018089.

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