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Relevant bibliographies by topics / Pirimidine

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Dissertations / Theses

Academic literature on the topic 'Pirimidine'

Author: Grafiati

Published: 11 March 2023

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Dissertations / Theses on the topic "Pirimidine"

1

Fantinel, Leonardo. "Síntese de 2-fenil-3H-pirimidin-4-onas 6-metilsubstituídas e 4- trifluormetil-2-ureído pirimidinas." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/4171.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This study was carried out in three parts: At first, three methods for the bromination of 6-alkylsubstituted 2-phenyl-3H-pyrimidin-4-ones was developed for the synthesis of: (i) a new series of 6-alkylsubstituted 5-bromo-2-phenyl-3H-pyrimidin-4-ones, (ii) a new series of 6-(1-bromoalkyl)-2-phenyl-3H-pyrimidin-4-ones, and (iii) e new series of 5-bromo-6-(1-bromoalkyl)-2-phenyl-3H-pyrimidin-4-ones. On the second part, the brominated pyrimidines obtained, were used to synthesize new 6-methylsubstituted 2-phenyl-3Hpyrimidin-4-ones from

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2

Bolcato, Chiara. "Progettazione sintesi e valutazione biologica di sistemi eterociclici quali antagonisti per i recettori adenosinici. Validazione di modelli recettoriali." Doctoral thesis, Università degli studi di Trieste, 2008. http://hdl.handle.net/10077/2567.

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2006/2007<br>La tesi illustra il lavoro di dottorato mirato allo sviluppo di nuovi antagonisti adenosinici attivi nei confronti dei vari sottotipi recettoriali del ligando naturale Adenosina.<br>XX Ciclo<br>1977

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3

Vaitiulionytė, Diana. "Furo[2,3-d]pirimidinų sintezė ir savybės." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2006. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2006~D_20060613_174528-81935.

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We report herein on the results of N- and O-alkylation of 5-cyano-2-methylsulfanyl-4(3H)- pyrimidinone with 4-substituted ω-bromoacetophenones. Synthesized N-(phenacyl)-4- pyrimidinones and 4-(phenacyloxy)pyrimidines with suitable substituents in pyrimidine ring are versatile synthons for the preparation of fused pyrimidine heterocycles. Chemical properties of new furo[2,3-d]pyrimidines were investigated. The structure of synthesized compounds was confirmed by data of 1H NMR, IR and UV spectra.

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4

Juškėnas, Robertas. "Triciklių heterosistemų, turinčių pirazolo[3,4-d]pirimidino fragmentą, sintezė. Intramolekulinės pirimidino azoto atomo reakcijos su O,O-acetaliais tyrimas." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140630_154058-49723.

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Heterociklų chemijos vystymasis turi didelę reikšmę įvairioms mokslo sritims ir pramonės raidai. Pagrindinis šios chemijos srities uždavinys – kurti naujus heterociklinių junginių sintezės metodus, leidžiančius paprasčiau, efektyviau gauti norimos struktūros junginius. Tai apima ne tik heterociklų formavimo būdus, bet ir jų funkcionalizavimą, leidžiantį sukurti įvairiomis cheminėmis ir fizikinėmis savybėmis pasižyminčių junginių įvairovę. Šios mokslo srities pasiekimai pritaikomi biochemijoje, farmacijoje, fotofizikoje ir kitose mokslo ir pramonės šakose. Šiame darbe buvo siekiama sukurti efek

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5

Sūdžius, Jurgis. "Pirimidino junginių - potencialių karboanhidrazių slopuklių - sintezė ir savybės." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110519_082321-15451.

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Šio darbo tikslas – pirimidino junginių – potencialių karboanhidrazių (CA) slopiklių –kūrimas. Teoriniai 4-[N-(pirimidin-4-il)]aminobenzensulfonamidų, turinčių pakaitus 2-, 5- ir 6-oje pirimidino žiedo padėtyje, sąveikos su aktyviuoju hCA centru tyrimai parodė, kad šie junginiai gali įsiterpti į aktyvųjį baltymo centrą ir su hCA turėtų sąveikauti kaip tipiški klasikiniai CA slopikliai. Tiksliniai 4-[N-(2,5,6-pakeisti pirimidin-4-il)amino]benzensulfonamidai sintetinti 4,6-dichlorpirimidinuose, 5-oje padėtyje turinčiuose cian-, formil- arba nitrogrupes, chloro atomą keičiant 4-aminobenzensulfona

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6

Scapin, Elisandra. "Pirazolo[1,5-a]pirimidinas: síntese e bromação." Universidade Federal de Santa Maria, 2006. http://repositorio.ufsm.br/handle/1/10375.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The synthesis of a series of 2-methyl-7-trichloromethylpyrazolo[1,5-a]pyrimidines from the cyclocondensation reaction of 3-amino-5-methylpyrazole with 1,1,1-trichloro-4- alkoxyalk-3-en-2-ones [CCl3C(O)CH=C(R1)OR where R1 = H, Me, Et, Pr, Bu, t-Bu e R = Me, Et] in good yields (69-98%) is reported. Also, was performed the synthesis of 2- methyl-7-arylpyrazolo[1,5-a]pyrimidines from de cyclocondensation reaction of 3-amino-5-methylpyrazole with β-dimethylaminovinyl ketones [R2C(O)CH=CHNMe2, where R= Ph, Ph-4-NO2, Ph-4-Me, Ph-4-Br, P

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7

MONTE, Zenaide Severina do. "Pirimidinas: de potenciais fármacos a marcadores fluorescentes." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/19607.

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Submitted by Fabio Sobreira Campos da Costa (fabio.sobreira@ufpe.br) on 2017-07-13T14:09:49Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Zenaide S Monte - Tese Doutorado - Defesa 15-jul-2016.pdf: 10509605 bytes, checksum: 9a625f96607c0ccae6d58b896ba38772 (MD5)<br>Made available in DSpace on 2017-07-13T14:09:49Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Zenaide S Monte - Tese Doutorado - Defesa 15-jul-2016.pdf: 10509605 bytes, checksum: 9a625f96607c0ccae6d58b896ba38772 (MD5) Prev

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8

Zanelato, Aurelio Izuka. "Investigação teórica do espalhamento de elétrons pela molécula de Pirimidina (C4H4N2)." Universidade Federal do Amazonas, 2014. http://tede.ufam.edu.br/handle/tede/4814.

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Submitted by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-01-26T14:01:02Z No. of bitstreams: 1 Dissertação - Aurelio Izuka Zanelato.pdf: 1806931 bytes, checksum: 4c3ce4091083533c8e83aecb05590538 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 2016-01-28T12:40:37Z (GMT) No. of bitstreams: 1 Dissertação - Aurelio Izuka Zanelato.pdf: 1806931 bytes, checksum: 4c3ce4091083533c8e83aecb05590538 (MD5)<br>Approved for entry into archive by Divisão de Documentação/BC Biblioteca Central (ddbc@ufam.edu.br) on 20

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9

Barreto, Igor Ramon Lomba. "Planejamento de derivados 1H-pirazolo[1,5-a]pirimidina com potencial atividade antichagásica." Niterói, 2018. https://app.uff.br/riuff/handle/1/5822.

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Submitted by Biblioteca da Faculdade de Farmácia (bff@ndc.uff.br) on 2018-02-26T14:19:29Z No. of bitstreams: 1 Igor Ramon Lomba Barreto.pdf: 3736181 bytes, checksum: ecfcbc6577d554a095f221827960499b (MD5)<br>Made available in DSpace on 2018-02-26T14:19:29Z (GMT). No. of bitstreams: 1 Igor Ramon Lomba Barreto.pdf: 3736181 bytes, checksum: ecfcbc6577d554a095f221827960499b (MD5)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>A doença de Chagas, causada pelo parasita Trypanosoma cruzi, é uma infecção que possui maior impacto na América Latina, onde a doença é endêmica em vários

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10

Vargas, Pâmela Schütz de. "Reações de β-enaminodicetonas com ncn dinucleófilos: obtenção de pirimidinas e sistemas heterocíclicos fundidos". Universidade Federal de Santa Maria, 2016. http://repositorio.ufsm.br/handle/1/4288.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>In this study the reactivity of β-enamino diketones [RC(O)C(=CHNMe2)C(O)CO2Et, R = C6H5, 4-Me-C6H4, 4-MeO-C6H4, 4-F-C6H4, 4-Br-C6H4, 4-NO2-C6H4, tien-2-il] with NCN bisnucleophiles as amidine and guanidine was investigated. The tiopirimidines ethyl 2-benzylthio-pyrimidine-4-carboxylates, (65-91 %) and Ethyl 2-metiltiopirimidine-4-carboxylates (69-91 %) were obtained in a highly regioselective manner by cyclocondensation reaction of β-enamino diketones with benzylisothiourea hydrochloride and methylisothiourea sulfate, respectivel

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