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1

Toulis, Panagiotis (Panos). "A Useful Pivotal Quantity." American Statistician 71, no. 3 (2017): 272–74. http://dx.doi.org/10.1080/00031305.2016.1237894.

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2

Yu, Philip L. H., Thomas Mathew, and Yuanyuan Zhu. "A generalized pivotal quantity approach to portfolio selection." Journal of Applied Statistics 44, no. 8 (2016): 1402–20. http://dx.doi.org/10.1080/02664763.2016.1214241.

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3

Kim, Joseph H. T., Sanghyun Ahn, and Soohan Ahn. "Parameter estimation of the Pareto distribution using a pivotal quantity." Journal of the Korean Statistical Society 46, no. 3 (2017): 438–50. http://dx.doi.org/10.1016/j.jkss.2017.01.004.

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4

Seo, Jung-In, Young Eun Jeon, and Suk-Bok Kang. "New Approach for a Weibull Distribution under the Progressive Type-II Censoring Scheme." Mathematics 8, no. 10 (2020): 1713. http://dx.doi.org/10.3390/math8101713.

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This paper proposes a new approach based on the regression framework employing a pivotal quantity to estimate unknown parameters of a Weibull distribution under the progressive Type-II censoring scheme, which provides a closed form solution for the shape parameter, unlike its maximum likelihood estimator counterpart. To resolve serious rounding errors for the exact mean and variance of the pivotal quantity, two different types of Taylor series expansion are applied, and the resulting performance is enhanced in terms of the mean square error and bias obtained through the Monte Carlo simulation. Finally, an actual application example, including a simple goodness-of-fit analysis of the actual test data based on the pivotal quantity, proves the feasibility and applicability of the proposed approach.
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5

Seo, Jung-In. "Inference for an exponentiated Pareto record values based on the pivotal quantity." Journal of the Korean Data And Information Science Society 30, no. 4 (2019): 885–93. http://dx.doi.org/10.7465/jkdi.2019.30.4.885.

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6

CHEN, ZHENMIN. "ESTIMATING THE SHAPE PARAMETER OF THE LOG-LOGISTIC DISTRIBUTION." International Journal of Reliability, Quality and Safety Engineering 13, no. 03 (2006): 257–66. http://dx.doi.org/10.1142/s0218539306002240.

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The log-logistic distribution is a useful distribution in survival analysis. Parameter estimation problems have been discussed by many authors. This paper focuses on the interval estimation for the shape parameter of the log-logistic distribution. Bain and Engelhardt3 gave confidence intervals for the parameters of a logistic distribution based on pivotal quantities formed by maximum likelihood estimators. Chen10 proposed another method for obtaining exact confidence intervals of the shape parameter of the log-logistic distribution. Compared with the existing methods for constructing confidence intervals for the parameters of the log-logistic distribution, the method given in Chen10 is easier to use. In the present paper, the pivotal quantity used in Chen10 is adjusted to improve the performance of statistical analysis. Monte Carlo simulation is conducted to compare the performance of different pivotal quantities. The simulation result shows that the adjusted pivotal quantity has better performance, and then should be recommended to the statistics users.
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7

Malekzadeh, Ahad, and Seyed Mahdi Mahmoudi. "Constructing a confidence interval for the ratio of normal distribution quantiles." Monte Carlo Methods and Applications 26, no. 4 (2020): 325–34. http://dx.doi.org/10.1515/mcma-2020-2070.

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AbstractIn this paper, to construct a confidence interval (general and shortest) for quantiles of normal distribution in one population, we present a pivotal quantity that has non-central t distribution. In the case of two independent normal populations, we propose a confidence interval for the ratio of quantiles based on the generalized pivotal quantity, and we introduce a simple method for extracting its percentiles, based on which a shorter confidence interval can be created. Also, we provide general and shorter confidence intervals using the method of variance estimate recovery. The performance of five proposed methods will be examined by using simulation and examples.
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8

Yang, H., and J. Zhang. "A Generalized Pivotal Quantity Approach to Analytical Method Validation Based on Total Error." PDA Journal of Pharmaceutical Science and Technology 69, no. 6 (2015): 725–35. http://dx.doi.org/10.5731/pdajpst.2015.01081.

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9

Hwang, Hyungtae. "A Bayesian Approach to Finite Population Sampling Using the Concept of Pivotal Quantity." Communications for Statistical Applications and Methods 10, no. 3 (2003): 647–54. http://dx.doi.org/10.5351/ckss.2003.10.3.647.

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10

Lee, Jeongwook, Joon Jin Song, Yongku Kim, and Jung In Seo. "Estimation and Prediction of Record Values Using Pivotal Quantities and Copulas." Mathematics 8, no. 10 (2020): 1678. http://dx.doi.org/10.3390/math8101678.

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Recently, the area of sea ice is rapidly decreasing due to global warming, and since the Arctic sea ice has a great impact on climate change, interest in this is increasing very much all over the world. In fact, the area of sea ice reached a record low in September 2012 after satellite observations began in late 1979. In addition, in early 2018, the glacier on the northern coast of Greenland began to collapse. If we are interested in record values of sea ice area, modeling relationships of these values and predicting future record values can be a very important issue because the record values that consist of larger or smaller values than the preceding observations are very closely related to each other. The relationship between the record values can be modeled based on the pivotal quantity and canonical and drawable vine copulas, and the relationship is called a dependence structure. In addition, predictions for future record values can be solved in a very concise way based on the pivotal quantity. To accomplish that, this article proposes an approach to model the dependence structure between record values based on the canonical and drawable vine. To do this, unknown parameters of a probability distribution need to be estimated first, and the pivotal-based method is provided. In the pivotal-based estimation, a new algorithm to deal with a nuisance parameter is proposed. This method allows one to reduce computational complexity when constructing exact confidence intervals of functions with unknown parameters. This method not only reduces computational complexity when constructing exact confidence intervals of functions with unknown parameters, but is also very useful for obtaining the replicated data needed to model the dependence structure based on canonical and drawable vine. In addition, prediction methods for future record values are proposed with the pivotal quantity, and we compared them with a time series forecasting method in real data analysis. The validity of the proposed methods was examined through Monte Carlo simulations and analysis for Arctic sea ice data.
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11

A. Nechval, Nicholas. "Optimization of Statistical Decisions for Age Replacement Problems via a New Pivotal Quantity Averaging Approach." American Journal of Theoretical and Applied Statistics 5, no. 2 (2016): 21. http://dx.doi.org/10.11648/j.ajtas.s.2016050201.14.

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12

Pascual, Francis, Sansi Yang, and Min Ye. "Monitoring Weibull Quantiles by EWMA Charts Based on a Pivotal Quantity Conditioned on Ancillary Statistics." Quality and Reliability Engineering International 33, no. 1 (2016): 103–19. http://dx.doi.org/10.1002/qre.1993.

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13

Lewis, Richard A., and Steven J. Novick. "A Generalized Pivotal Quantity Approach to the Parametric Tolerance Interval Test for Dose Content Uniformity Batch Testing." Statistics in Biopharmaceutical Research 4, no. 1 (2012): 28–36. http://dx.doi.org/10.1080/19466315.2011.636282.

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14

Nechval, N. A., G. Berzins, S. Balina, I. Steinbuka, and K. N. Nechval. "Constructing unbiased prediction limits on future outcomes under parametric uncertainty of underlying models via pivotal quantity averaging approach." Automatic Control and Computer Sciences 51, no. 5 (2017): 331–36. http://dx.doi.org/10.3103/s0146411617050054.

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15

Sossé, Saad Alaoui, Taoufiq Saffaj, and Bouchaib Ihssane. "Validation and Measurement Uncertainty Assessment of a Microbiological Method Using Generalized Pivotal Quantity Procedure and Monte-Carlo Simulation." Journal of AOAC INTERNATIONAL 101, no. 4 (2018): 1205–11. http://dx.doi.org/10.5740/jaoacint.17-0423.

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Abstract Recently, a novel and effective statistical tool called the uncertainty profile has been developed with the purpose of graphically assessing the validity and estimating the measurement uncertainty of analytical procedures. One way to construct the uncertainty profile is to compute the β-content, γ-confidence tolerance interval. In this study, we propose a tolerance interval based on the combination of the generalized pivotal quantity procedure and Monte-Carlo simulation. The uncertainty profile has been applied successfully in several fields. However, in order to further confirm its universality, this newer approach has been applied to assess the performance of an alternative procedure versus a reference procedure for counting of Escherichia coli bacteria in drinking water. Hence, the aims of this research were to expose how the uncertainty profile can be powerfully applied pursuant to ISO 16140 standards in the frame of interlaboratory study and how to easily make a decision concerning the validity of the procedure. The analysis of the results shows that after the introduction of a correction factor, the alternative procedure is deemed valid over the studied range because the uncertainty limits lie within the acceptability limits set at ±−0.3 log unit/100 ml for a β = 66.7% and γ = 90%.
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16

Wang, Fu-Kwun, Berihun Bizuneh, and Xiao-Bin Cheng. "EWMA chart based on Bayes-conditional pivotal quantity for Weibull percentiles under complete data and type-II censoring." Quality and Reliability Engineering International 34, no. 5 (2018): 707–17. http://dx.doi.org/10.1002/qre.2281.

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17

LU, MENGYING, and JIE MI. "STATISTICAL INFERENCE ABOUT AVAILABILITY OF SYSTEM WITH GAMMA LIFETIME AND REPAIR TIME." International Journal of Reliability, Quality and Safety Engineering 18, no. 01 (2011): 1–24. http://dx.doi.org/10.1142/s0218539311004007.

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Availability is an important measure of performance of repairable system. The steady state system availability has special importance since it demonstrates the performance of a system after it has been operated for long. The statistical inference about the steady state availability are particularly useful for practitioners. Much work has been done in this regard. Most of these researches proposed certain pivotal quantities for constructing confidence intervals of the steady state availability. Assuming both the lifetime and repair time follow gamma distribution with known shape parameters and unknown scale parameters, we propose a pivotal quantity for making inferences, and further derive the likelihood ratio tests. Tables of critical values are given for the convenience of applying the two-sided likelihood ratio test. Confidence intervals are also obtained by converting the acceptance regions.
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18

Pan, Xia, Yuning Gao, Dong Guo, and Wenyin Cheng. "Does Higher Education Promote Firm Innovation in China?" Sustainability 12, no. 18 (2020): 7326. http://dx.doi.org/10.3390/su12187326.

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Endogenous growth theories have underpinned the pivotal role of education in innovation. However, our empirical study uncovers a mixed effect of higher education on firm innovation in China. Using Chinese Patent Census Data, a unique dataset, this paper is able to quantify innovation in China by incorporating a quality dimension for the first time. By merging the patent data with the Chinese Industrial Enterprise Database and province-level data on education, we find that the number of higher education institutions has a negative impact on firm-level innovation. However, the quantity of elite higher education institutions at the provincial level exerts a positive impact on firm innovation. In addition, heterogeneity analyses show that the effect of elite higher education on firm innovation is significantly positive for privately owned enterprises, but insignificant for state- and foreign-owned enterprises. Furthermore, the positive effect of elite higher education on innovation in high-tech industries is larger than in other industries.
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19

Tashenova, Zhuldyz, Elmira Nurlybaeva, and Anarbay Kudaykulov. "Method Preparation and Solution Algorithm for Resolving Stationary Problem of a Rod under Thermo - Stressed Condition Restrained at both Ends Affected by Heat Exchange and Heat Flows." Advanced Materials Research 875-877 (February 2014): 858–62. http://dx.doi.org/10.4028/www.scientific.net/amr.875-877.858.

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In this article the computational algorithm and solution technique of the problem of identifying temperature field as well as strain and stress components throughout the rod length exposed to heat flows supplied to cross section areas of both ends and heat exchange in its lateral surface on the basis of heat quantity variation law are developed. Herewith the tested rod physical and mechanical properties are taken into account. The solutions so acquired are presented in a graphical form. Certain dependencies between temperature pivotal values and capacities of the set heat flows are found.
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20

Nkurunziza, Sévérien, and Fuqi Chen. "Equivariance and Generalized Inference in Two-Sample Location-Scale Families." Journal of Probability and Statistics 2011 (2011): 1–16. http://dx.doi.org/10.1155/2011/474826.

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We are interested in-typical Behrens-Fisher problem in general location-scale families. We present a method of constructing generalized pivotal quantity (GPQ) and generalizedPvalue (GPV) for the difference between two location parameters. The suggested method is based on the minimum risk equivariant estimators (MREs), and thus, it is an extension of the methods based on maximum likelihood estimators and conditional inference, which have been, so far, applied to some specific distributions. The efficiency of the procedure is illustrated by Monte Carlo simulation studies. Finally, we apply the proposed method to two real datasets.
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21

Delfi, Masoud, Matineh Ghomi, Ali Zarrabi, et al. "Functionalization of Polymers and Nanomaterials for Biomedical Applications: Antimicrobial Platforms and Drug Carriers." Prosthesis 2, no. 2 (2020): 117–39. http://dx.doi.org/10.3390/prosthesis2020012.

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The use of polymers and nanomaterials has vastly grown for industrial and biomedical sectors during last years. Before any designation or selection of polymers and their nanocomposites, it is vital to recognize the targeted applications which require these platforms to be modified. Surface functionalization to introduce the desired type and quantity of reactive functional groups to target a cell or tissue in human body is a pivotal approach to improve the physicochemical and biological properties of these materials. Herein, advances in the functionalized polymer and nanomaterials surfaces are highlighted along with their applications in biomedical fields, e.g., antimicrobial therapy and drug delivery.
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22

Boubakar, Traoré, Diabaté Lassina, Touré Belco, and Fané Abdou. "The Shortest Confidence Interval for the Mean of a Normal Distribution." International Journal of Statistics and Probability 7, no. 2 (2018): 33. http://dx.doi.org/10.5539/ijsp.v7n2p33.

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An interesting topic in mathematical statistics is that of the construction of the confidence intervals. Two kinds of intervals which are both based on the method of pivotal quantity are the shortest confidence interval and the equal tail confidence intervals. The aim of this paper is to clarify and comment on the finding of such intervals and to investigation the relation between the two kinds of intervals. In particular, we will give a construction technique of the shortest confidence intervals for the mean of the standard normal distribution. Examples illustrating the use of this technique are given.
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23

Nhuong, Do Thi, and Chu Tuan Anh. "Development of Vietnamese Medical Staff in the Period of Accelerated Industrialization and Modernization of the Country and International Integration." Asian Journal of Social Science Studies 5, no. 1 (2020): 39. http://dx.doi.org/10.20849/ajsss.v5i1.729.

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Medical staff holds a pivotal role in the Vietnamese health system, and is crucial to the efficiency and quality of health care services in Vietnam. It is their professional and dedicated work that is a permanent basis to guarantee protection of and care for people’s health in the provision of health care services to people in all regions, including remote areas, borders and islands. The continuous growth in the quantity and quality of health workers in Vietnam has affirmed the right leadership of the Communist Party of Vietnam in building this health workforce over the years.
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24

Palacio, Facundo Xavier. "Seed dispersal effectiveness by frugivorous birds: Identifying functional equivalent species in bird assemblages." Avian Biology Research 12, no. 3 (2019): 103–8. http://dx.doi.org/10.1177/1758155919832189.

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Seed dispersal by birds is a pivotal ecosystem function worldwide; yet, the rapid and ongoing global biodiversity loss poses a major threat to this essential ecosystem service. Seed dispersal effectiveness (SDE) is a key outcome of the interaction, represented by the product of seed dispersal quantity (number of seed dispersed) and quality (probability of recruitment of dispersed seeds). Therefore, identifying functional equivalent species in terms of SDE should become a key issue for bird conservation, since the effects of local extinctions on seed dispersal services may be weakened by remaining equivalent species. However, a method to quantitatively identify functional equivalent species in frugivorous bird assemblages is still lacking. To estimate SDE overlap between seed dispersers and assess whether two species may be functionally equivalent, I apply a novel nonparametric niche overlap index based on kernel functions and null models to test its statistical significance. For each bird species, I account for intraspecific variation in seed dispersal effectiveness to obtain a distribution of seed dispersal effectiveness values, an often neglected source of variation in seed dispersal assemblages. Non-significant differences in seed dispersal effectiveness overlap support the hypothesis that two species are functional equivalent, thus playing similar functional roles. The model proposed is applicable to any other quantity or quality component and is independent from the method or sampling design used to quantify SDE. The identification of functional equivalent species in seed dispersal assemblages adds to the theoretical framework of seed dispersal effectiveness and offers new insights into the ecology of the seed dispersal service provided by birds.
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25

Han, Li. "The Modeling of Sky in the Large Virtual Scene." Applied Mechanics and Materials 543-547 (March 2014): 3029–32. http://dx.doi.org/10.4028/www.scientific.net/amm.543-547.3029.

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When developing a project about big games or the large virtual simulation, the modeling of sky is a pivotal part, in order to effectively reflect the authenticity of the scene. However, because of the demand of updating data in a large quantity real-time, the theme is always a difficult problem to be researched that the ordinary simulation cannot satisfy. According to the researching theme, the paper puts forward a method which replace the required texture of the sky model in real time. The approach is not only meet the simulation on computers of low configuration, but also reflects the authenticity of the virtual scene better.
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26

Yu, Jianqi. "Hierarchical Missing Data and Multivariate Behrens–Fisher Problem." Journal of Mathematics 2021 (January 27, 2021): 1–9. http://dx.doi.org/10.1155/2021/8837044.

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This article firstly defines hierarchical data missing pattern, which is a generalization of monotone data missing pattern. Then multivariate Behrens–Fisher problem with hierarchical missing data is considered to illustrate that how ideas in dealing with monotone missing data can be extended to deal with hierarchical missing pattern. A pivotal quantity similar to the Hotelling T 2 is presented, and the moment matching method is used to derive its approximate distribution which is for testing and interval estimation. The precision of the approximation is illustrated through Monte Carlo data simulation. The results indicate that the approximate method is very satisfactory even for moderately small samples.
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27

Bueno-Pardo, Juan, Graham J. Pierce, Edna Cabecinha, et al. "Trends and drivers of marine fish landings in Portugal since its entrance in the European Union." ICES Journal of Marine Science 77, no. 3 (2020): 988–1001. http://dx.doi.org/10.1093/icesjms/fsaa010.

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Abstract Marine landings in Portugal have decreased at a higher rate than fishing effort in the last 20 years. Identifying the variables driving the quantity and composition of landings is pivotal to understand the dynamics of the fisheries sector, which entails complex social and environmental aspects. In this study, we investigate the main drivers of marine fish landings in continental Portugal between 1989 and 2014. To identify common trends in time series, and quantify the importance of environmental factors, we applied a dynamic factor analysis considering four regions and three types of gear (trawling, purse-seine, and a multi-gear fishery). Our results show the importance of fishing effort as the most relevant factor driving marine landings in Portugal, both at the long and short terms. In addition, the effect of environmental factors such as the winter river discharge and the spring East Atlantic Teleconnection index should not be neglected, probably through mechanisms affecting coastal productivity. We provide a comprehensive amount of information that permits to improve our understanding of the trends of the most important commercial species in Portugal during the period of study.
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28

Beh, Eric. "Exploring How to Simply Approximate the P-value of a Chi-squared Statistic." Austrian Journal of Statistics 47, no. 3 (2018): 63–75. http://dx.doi.org/10.17713/ajs.v47i3.757.

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Calculating the p-value of any test statistic is of paramount importance to all statistically minded researchers across all areas of study. Many, these days, take for granted how the p-value is calculated and yet it is a pivotal quantity in all forms of statistical analysis. For the study of 2x2 tables where dichotomous variables are assessed for association, the chi-squared statistic, and its p-value, are fundamental quantities to all analysts, especially those in the health and allied disciplines. Examining the association between dichotomous variables is easily achieved through a very simple formula for the chi-squared statistic and yet the p-value of this statistic requires far more computational power.This paper proposes and explores a very simple approximation of the p-value for a chi-squared statistic given its degrees of freedom. After providing a review a variety of common ways for determining the quantile of the chi-squared distribution given the level of significance and degrees of freedom, we shall derive an approximation based on the classic quantile formula given in 1977 by D. C. Hoaglin. We examine this approximation using a simple 2x2 contingency table example then show that it is extremely precise for all chi-squared values ranging from 0 to 50.
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29

Warren, Christian. "Toxic Purity: The Progressive Era Origins of America' s Lead Paint Poisoning Epidemic." Business History Review 73, no. 4 (1999): 705–36. http://dx.doi.org/10.2307/3116131.

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This paper examines a pivotal moment in the history of the built environment in America. At the beginning of the twentieth century, factions within the American paint industry fought in state and federal legislatures over the definition of paint: What was pure paint? Were new paint formulations to be encouraged, or labeled “adulterated”? Was the known toxicity of lead to be a consideration? Despite some opponents' recourse to a rhetoric of toxicity and public health, all sides agreed that the best paints contained a significant quantity of lead, and that government should stay out of setting industry standards. This accord all but assured that Americans would apply tons of lead paint on the walls of their homes.
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30

Mehmood, Rashid, Muhammed Hisyam Lee, Muhammad Riaz, and Iftikhar Ali. "Generalized Performance Measures of X- Control Charts Based on Different Sampling Schemes." Journal of Probability and Statistics 2019 (June 4, 2019): 1–11. http://dx.doi.org/10.1155/2019/5269357.

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Different versions of X- control chart structure are available under various ranked set strategies. In these control charts, computation of performance measures was carried out through Monte Carlo simulation method (MCSM). In this article, we have defined a generalized structure of X- control charts under variant sampling strategies followed by derivation of their different performance measures. For the derivation of different performance measures, we have proposed pivotal quantity. For comparative analysis, we have presented results of generalized performance measures by involving numerical method (NM) as computation. We found that values of generalized performance measures based on NM are almost similar to values of performance measures based on MCSM. Also, NM is time efficient and can be considered as an alternative of MCSM.
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31

Wei, Shuanzeng, and Tahseen Al-Saleem. "The Pathology and Molecular Genetics of Sarcomatoid Renal Cell Carcinoma: A mini-review." Journal of Kidney Cancer and VHL 4, no. 2 (2017): 19–23. http://dx.doi.org/10.15586/jkcvhl.2017.70.

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Sarcomatoid renal cell carcinoma is a highly aggressive tumor. It is not a distinct histologic entity as it can be found in any subtypes of renal cell carcinoma. Recent molecular and genetic evidence suggest that sarcomatoid component is transformed from a common progenitor of the associated renal cell carcinoma, and the TP53 gene plays a pivotal role in this process. The presence of sarcomatoid carcinoma indicates poor prognosis, which also correlates with the amount of the sarcomatoid component. Therefore, the presence and quantity of sarcomatoid component should be reflected in pathology reports. However, pathology reporting seems to vary among laboratories prompting the need for a unified reporting system. We propose a pathology reporting system similar to that of transformed follicular lymphoma that is consistent with the molecular pathogenesis to ensure uniform reporting.
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32

Mailhammer, Robert, William W. Kruger, and Alexander Makiyama. "Type frequency influences phonological generalizations: Eliminating stressed open syllables with short vowels in West Germanic." Journal of Germanic Linguistics 27, no. 3 (2015): 205–37. http://dx.doi.org/10.1017/s1470542715000069.

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A pivotal process in the loss of phonological quantity in West Germanic languages is what is traditionally known as Open Syllable Lengthening. Existing accounts have found no explanation for why languages such as English apply this change in less than 50% of the relevant cases. This paper presents the results of a corpus investigation of four West Germanic languages showing that whether Open Syllable Lengthening occurs in more than 50% of predicted cases correlates with the ratio of closed syllables with short vowels to open syllables with long vowels. We interpret this as the result of frequency effects that have markedly shaped the application of Open Syllable Lengthening in West Germanic. This has implications for phonological change in general, as well as for the relationship between stress and syllable structure in West Germanic languages.*
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33

Kim, Yuho, Matthew Triolo, and David A. Hood. "Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–16. http://dx.doi.org/10.1155/2017/3165396.

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Mitochondria are characterized by its pivotal roles in managing energy production, reactive oxygen species, and calcium, whose aging-related structural and functional deteriorations are observed in aging muscle. Although it is still unclear how aging alters mitochondrial quality and quantity in skeletal muscle, dysregulation of mitochondrial biogenesis and dynamic controls has been suggested as key players for that. In this paper, we summarize current understandings on how aging regulates muscle mitochondrial biogenesis, while focusing on transcriptional regulations including PGC-1α, AMPK, p53, mtDNA, and Tfam. Further, we review current findings on the muscle mitochondrial dynamic systems in aging muscle: fusion/fission, autophagy/mitophagy, and protein import. Next, we also discuss how endurance and resistance exercises impact on the mitochondrial quality controls in aging muscle, suggesting possible effective exercise strategies to improve/maintain mitochondrial health.
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34

WU, SHUO-JYE, HSIU-MEI LEE, and DAR-HSIN CHEN. "ESTIMATIONS FOR A SIMPLE STEP-STRESS MODEL WITH PROGRESSIVELY TYPE-II CENSORED DATA." International Journal of Reliability, Quality and Safety Engineering 12, no. 05 (2005): 385–95. http://dx.doi.org/10.1142/s0218539305001902.

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With today's high technology, some life tests result in no or very few failures by the end of test. In such cases, an approach is to do life test at higher-than-usual stress conditions in order to obtain failures quickly. This study discusses the point and interval estimations of parameters on the simple step-stress model in accelerated life testing with progressive type II censoring. An exponential failure time distribution with mean life that is a log-linear function of stress and a cumulative exposure model are considered. We derive the maximum likelihood estimators of the model parameters. Confidence intervals for the model parameters are established by using pivotal quantity and can be applied to any sample size. A numerical example is investigated to illustrate the proposed methods.
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35

JAYACHANDRAN, S. ARUL, V. KALYANARAMAN, and R. NARAYANAN. "A CO-ROTATION BASED SECANT MATRIX PROCEDURE FOR ELASTIC POSTBUCKLING ANALYSIS OF TRUSS STRUCTURES." International Journal of Structural Stability and Dynamics 04, no. 01 (2004): 1–19. http://dx.doi.org/10.1142/s0219455404001124.

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To investigate the geometrically nonlinear behavior of space structures using finite elements, the total Lagrangian (TL), updated Lagrangian (UL) and co-rotational (CR) procedures have been used by researchers. For 3D truss structures, the CR formulation has been reported to be computationally more efficient as it possesses the rigid body displacement components during deformations. In this paper, the secant stiffness matrix of truss element will be derived using a simple co-rotational, total Lagrangian (CR–TL) formulation. The incremental rotation matrix, which is the pivotal quantity in the CR formulation, is derived from geometric principles. The secant stiffness matrix is presented in terms of the natural degrees-of-freedom of the truss element. The efficiency and reliability of the present formulation is demonstrated in the solution of several truss problems involving the postbuckling behavior.
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36

Musvoto, Saratiel Weszerai. "Introducing The Representational Measurement Project In Accounting." Journal of Applied Business Research (JABR) 27, no. 5 (2011): 97. http://dx.doi.org/10.19030/jabr.v27i5.5596.

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<span style="font-family: Times New Roman; font-size: small;"> </span><p style="margin: 0in 0.5in 0pt; text-align: justify;" class="MsoNormal"><span lang="EN-GB" style="font-size: 10pt; mso-fareast-language: EN-GB; mso-ansi-language: EN-GB;"><span style="font-family: Times New Roman;">This study introduces a representational measurement (a theory that establishes measurement in the social sciences) perspective to the accounting concept of measurement. Accounting studies have long sought to establish foundations (theory) of measurement in accounting without success. This is because the accounting concept of measurement is based on the axioms of quantity which ultimately result in the classical theory of measurement and are not suitable for social science disciplines such as accounting, but rather for the natural sciences. The measurement of attributes of social science phenomena does not give rise to a natural concatenation operation, which is pivotal to invoking a theoretical concept of an absolute continuous quantity that forms the basis of the classical theory of measurement. As a result, this study suggests criteria whose development might eventually lead to the construction of representational measurements in accounting.<span style="mso-spacerun: yes;"> </span></span></span></p><span style="font-family: Times New Roman; font-size: small;"> </span>
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37

Kavouras, Menelaos, Emmanouil E. Malandrakis, Eleni Golomazou, et al. "Hox gene expression profiles during embryonic development of common sole." Animal Biology 69, no. 2 (2019): 183–98. http://dx.doi.org/10.1163/15707563-17000123.

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Abstract Common sole (Solea solea) aquaculture production is based mostly on wild-caught breeders. Recently, the successful reproduction of first-generation fish that were reared in captivity was accomplished. A consistent good quality and quantity of produced eggs throughout the year, and of next-generation broodstock, is important for reducing the overall cost of production. Hox genes play a pivotal role in normal embryonic development and alterations of their temporal expression level may be important for egg viability. Expression profile analysis of five hox genes (hoxa1a, hoxa2a, hoxa2b, hoxb1a and hoxb1b) involved in early embryonic development and of hoxa13a, which is involved in late stages, was carried out. Results revealed a premature and/or maternal expression of hoxa13a in sole embryos, and the detection of hoxa2a and hoxa2b genes as members of paralog group 2. Principal Component Analysis of hox gene expression in 54 ± 6 hours post fertilization embryos coming from wild-caught broodstock and a first-generation one reared in the hatchery, unveiled that these broodstocks are clearly distinct. In addition, their pairwise comparison revealed significant differences in the expression levels of hoxb1a and hoxb1b genes. Hox gene regulation during embryonic development could give valuable insight into rearing sole broodstocks with different origin in concert, and also into gaining a steady mass production of eggs, either in quality or quantity, all year round.
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38

Kembe, M. M., A. R. Kimbir, and E. M. Ogbuagu. "Minimizing the Cost of Transporting Goods Produced in an Integrated Foods Company." NIGERIAN ANNALS OF PURE AND APPLIED SCIENCES 6 (December 28, 2015): 106–11. http://dx.doi.org/10.46912/napas.15.

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The transportation cost of goods in any company or organization is a pivotal element in determining the total cost of production and also the net profit that will be made. The main aim of this study is to minimize the cost of transporting goods produced at Grand Cereals Limited, Jos, which is reducing the cost of transportation from the major plant where the goods are produced to the various distribution centers. Data was collected on the average quantity of Brabusco Maize Flour (10 kg), Grand Pure Soya Oil (10 litres), Vita Chicks Pelletized Feeds (25 kg, 9 mm) and Royal Layer Concentrate Feeds (25 kg) produced monthly at the Jos plant, the average quantity demanded by major distributors across the country (Yola, Dutse, Minna, Abuja, Aba, Onitsha, Calabar and Ikeja) and the cost of transporting them. The Vogel's Approximation Method of the TORA Optimization System Software was used in solving the formulated transportation problem, and an optimal solution of N3,427,821.00 was obtained, which reduced the monthly transportation cost by N332,179.00. Furthermore, sensitivity analysis was carried out on the parameters after the optimal solution was obtained, which shows that the optimal solution is strongly sensitive to changes in the problem parameters. It was concluded that this work has reduced the transportation cost of the company and therefore recommended to the management of the company for adoption in planning their transportation schedule at a minimum cost.
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39

Sutter, Louis, and Matthias Albrecht. "Synergistic interactions of ecosystem services: florivorous pest control boosts crop yield increase through insect pollination." Proceedings of the Royal Society B: Biological Sciences 283, no. 1824 (2016): 20152529. http://dx.doi.org/10.1098/rspb.2015.2529.

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Insect pollination and pest control are pivotal functions sustaining global food production. However, they have mostly been studied in isolation and how they interactively shape crop yield remains largely unexplored. Using controlled field experiments, we found strong synergistic effects of insect pollination and simulated pest control on yield quantity and quality. Their joint effect increased yield by 23%, with synergistic effects contributing 10%, while their single contributions were 7% and 6%, respectively. The potential economic benefit for a farmer from the synergistic effects (12%) was 1.8 times greater than their individual contributions (7% each). We show that the principal underlying mechanism was a pronounced pest-induced reduction in flower lifetime, resulting in a strong reduction in the number of pollinator visits a flower receives during its lifetime. Our findings highlight the importance of non-additive interactions among ecosystem services (ES) when valuating, mapping or predicting them and reveal fundamental implications for ecosystem management and policy aimed at maximizing ES for sustainable agriculture.
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40

Joanisse, Sophie, Changhyun Lim, James McKendry, Jonathan C. Mcleod, Tanner Stokes, and Stuart M. Phillips. "Recent advances in understanding resistance exercise training-induced skeletal muscle hypertrophy in humans." F1000Research 9 (February 24, 2020): 141. http://dx.doi.org/10.12688/f1000research.21588.1.

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Skeletal muscle plays a pivotal role in the maintenance of physical and metabolic health and, critically, mobility. Accordingly, strategies focused on increasing the quality and quantity of skeletal muscle are relevant, and resistance exercise is foundational to the process of functional hypertrophy. Much of our current understanding of skeletal muscle hypertrophy can be attributed to the development and utilization of stable isotopically labeled tracers. We know that resistance exercise and sufficient protein intake act synergistically and provide the most effective stimuli to enhance skeletal muscle mass; however, the molecular intricacies that underpin the tremendous response variability to resistance exercise-induced hypertrophy are complex. The purpose of this review is to discuss recent studies with the aim of shedding light on key regulatory mechanisms that dictate hypertrophic gains in skeletal muscle mass. We also aim to provide a brief up-to-date summary of the recent advances in our understanding of skeletal muscle hypertrophy in response to resistance training in humans.
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41

Verma, Apoorv, Alok Kumar, and N. B. Singh. "Application of Multi Linear Model for Forecasting Municipal Solid Waste Generation in Lucknow City: A Case Study." Current World Environment 14, no. 3 (2019): 421–32. http://dx.doi.org/10.12944/cwe.14.3.10.

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The objective of this study is to forecast the Municipal Solid Waste (MSW) quantity output in Lucknow city by 2025, establishing a relationship between various socio-economic variables and waste generated using Multiple Linear Regression Analysis (MLRA). It is found that the rate of generation of MSW in Lucknow increases after 1383 M ton d-1 in the year 2015 to 2075 M ton d-1 in the year 2025 and per capita waste increases after 0.465 kg capita-1 day-1 in 2015 to 0.616 kg capita-1 day-1 in 2025 respectively. The outcomes of the research are reliable to ascertain waste generation quantities in future, a pool of factors pivotal in the prevalent composition of the waste and a feasible way ahead towards a proper MSW management system as per the varying composition of solid wastes. The statistics provided in this paper is very useful for proper arrangement and executing the best waste management system in Lucknow City to avoid system failures.
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42

Zhang, Deng Zhi, and Bin Quan. "Research on Learning Beliefs and Strategies of Freshmen's Vocabulary Based on Regression Analysis and Mathematical Statistics." Applied Mechanics and Materials 380-384 (August 2013): 1886–90. http://dx.doi.org/10.4028/www.scientific.net/amm.380-384.1886.

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The teaching goals of higher vocational college English courses require English workers to directly face the problems of students English vocabulary learning. The quantity of vocabulary directly affects the improvement of many language abilities of listening, speaking, reading and writing, and the vocabulary teaching is the basis and pivotal issue of English teaching. This paper firstly analyzes the current situation of vocabulary learning of higher vocational colleges freshmen, and it provides the urgently discussed problem and research methods of vocabulary learning of current higher vocational colleges freshmen. It uses linear regression to discuss and analyze the importance of vocabulary learning, and it has the corresponding empirical study. This paper uses the latest edition SPSS19.0 of the statistical package for social sciences to have statistical analysis of the survey data, and it puts forward the English vocabulary teaching strategy that is suitable for higher vocational colleges. In this way it can cultivate the cognitive thinking ability of students' vocabulary learning to improve the efficiency of learning vocabulary.
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43

Thiericke, Ralf. "Drug discovery from Nature: automated high-quality sample preparation." Journal of Automated Methods and Management in Chemistry 22, no. 5 (2000): 149–57. http://dx.doi.org/10.1155/s1463924600000249.

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Secondary metabolites from plants, animals and microorganisms have been proven to be an outstanding source for new and innovative drugs and show a striking structural diversity that supplements chemically synthesized compounds or libraries in drug discovery programs. Unfortunately, extracts from natural sources are usually complex mixtures of compounds:: often generated in time consuming and for the most part manual processes. As quality and quantity of the provided samples play a pivotal role in the success of high-throughput screening programs this poses serious problems. In order to make samples of natural origin competitive with synthetic compound libraries, we devised a novel, automated sample preparation procedure based on solid-phase extraction (SPE). By making use of a modified Zymark RapidTrace®SPE workstation an easy-to-handle and effective fractionation method has been developed which allows the generation of highquality samples from natural origin, fulfilling the requirements of an integration into high-throughput screening programs.
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44

Pham, Van Thinh, Hong-Tham T. Nguyen, Duyen Thi Cam Nguyen, et al. "Process Optimization by a Response Surface Methodology for Adsorption of Congo Red Dye onto Exfoliated Graphite-Decorated MnFe2O4 Nanocomposite: The Pivotal Role of Surface Chemistry." Processes 7, no. 5 (2019): 305. http://dx.doi.org/10.3390/pr7050305.

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Natural graphite, a locally available, eco-friendly, and low-cost carbonaceous source, can be easily transformed into exfoliated graphite (EG) with many surface functional groups via a chemical oxidation route. Combination between EG and magnetic MnFe2O4 is a promising strategy to create a hybrid kind of nanocomposite (EG@MnFe2O4) for the efficient adsorptive removal of Congo red (CR) dye from water. Here, we reported the facile synthesis and characterization of chemical bonds of EG@MnFe2O4 using several techniques such as Fourier-transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS). In particular, the quantity method by Boehm titration was employed to identify the content of functional groups: Carboxylic acid (0.044 mmol/g), phenol (0.032 mmol/g), lactone (0.020 mmol/g), and total base (0.0156 mmol/g) on the surface of EG@MnFe2O4. Through the response surface methodology-optimized models, we found a clear difference in the adsorption capacity between EG-decorated MnFe2O4 (62.0 mg/g) and MnFe2O4 without EG decoration (11.1 mg/g). This result was also interpreted via a proposed mechanism to elucidate the contribution of surface functional groups of EG@MnFe2O4 to adsorption efficiency towards CR dye.
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45

Nordin, Aimi Norhanani, Gabriel Hoh Teck Ling, Mou Leong Tan, Chin Siong Ho, and Hishamuddin Mohd Ali. "Spatial and Non-Spatial Factors Influencing Willingness to Pay (WTP) for Urban Green Spaces (UGS): A Review." Journal of Sustainable Development 13, no. 6 (2020): 130. http://dx.doi.org/10.5539/jsd.v13n6p130.

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With numerous ecosystem services of urban green spaces (UGS), contributing to sustainability and a better quality of life, UGS provision is perceived as a pivotal role in urban planning. However, concern arises as to what extent local governments have effectively provided good quality and adequate quantity of UGS for the public? Provisioning those UGS aspects has been given a low priority due to insufficient resources and the limited budget allocated by local governments. As such, maintenance and management effectiveness of UGS is detrimentally affected, resulting in disused, overused spaces and thus hot spots for crimes. Therefore, public monetary contribution via taxation is suggested as an alternative to ensuring the continuity and sustainability of UGS services. This review paper is vital to identify and showcase specific factors and mediators, influencing the willingness to pay (WTP) of residents/users for UGS services. Methodologically, after conducting Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for the purpose of article screening and selection based on the two primary databases (Google Scholar and Elsevier), this paper reviewed 18 journal articles, from the year 2013 to 2020. Along with the indirect sub-factors, namely environmental behaviour/attitude and socioeconomic profiles of users, there are three main spatial and non-spatial variables (factors) identified: (i) accessibility/proximity to the nearest UGS; (ii) quantity/adequacy of UGS; and (iii) quality of UGS within a township area, influencing satisfaction and enjoyment as well as reasons and frequency of park visiting of users (mediators), which consequently affect their WTP for UGS.
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46

Gao, Jing, Kehan Bai, and Wenhao Gui. "Statistical Inference for the Inverted Scale Family under General Progressive Type-II Censoring." Symmetry 12, no. 5 (2020): 731. http://dx.doi.org/10.3390/sym12050731.

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Two estimation problems are studied based on the general progressively censored samples, and the distributions from the inverted scale family (ISF) are considered as prospective life distributions. One is the exact interval estimation for the unknown parameter θ , which is achieved by constructing the pivotal quantity. Through Monte Carlo simulations, the average 90 % and 95 % confidence intervals are obtained, and the validity of the above interval estimation is illustrated with a numerical example. The other is the estimation of R = P ( Y < X ) in the case of ISF. The maximum likelihood estimator (MLE) as well as approximate maximum likelihood estimator (AMLE) is obtained, together with the corresponding R-symmetric asymptotic confidence intervals. With Bootstrap methods, we also propose two R-asymmetric confidence intervals, which have a good performance for small samples. Furthermore, assuming the scale parameters follow independent gamma priors, the Bayesian estimator as well as the HPD credible interval of R is thus acquired. Finally, we make an evaluation on the effectiveness of the proposed estimations through Monte Carlo simulations and provide an illustrative example of two real datasets.
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47

Keuper, Michaela. "On the role of macrophages in the control of adipocyte energy metabolism." Endocrine Connections 8, no. 6 (2019): R105—R121. http://dx.doi.org/10.1530/ec-19-0016.

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The crosstalk between macrophages (MΦ) and adipocytes within white adipose tissue (WAT) influences obesity-associated insulin resistance and other associated metabolic disorders, such as atherosclerosis, hypertension and type 2 diabetes. MΦ infiltration is increased in WAT during obesity, which is linked to decreased mitochondrial content and activity. The mechanistic interplay between MΦ and mitochondrial function of adipocytes is under intense investigation, as MΦ and inflammatory pathways exhibit a pivotal role in the reprogramming of WAT metabolism in physiological responses during cold, fasting and exercise. Thus, the underlying immunometabolic pathways may offer therapeutic targets to correct obesity and metabolic disease. Here, I review the current knowledge on the quantity and the quality of human adipose tissue macrophages (ATMΦ) and their impact on the bioenergetics of human adipocytes. The effects of ATMΦ and their secreted factors on mitochondrial function of white adipocytes are discussed, including recent research on MΦ as part of an immune signaling cascade involved in the ‘browning’ of WAT, which is defined as the conversion from white, energy-storing adipocytes into brown, energy-dissipating adipocytes.
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48

Yao, Li-Juan, and Qing-Yuan Sun. "Characterization of Aurora-A in porcine oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization and cleavage." Zygote 13, no. 1 (2005): 23–30. http://dx.doi.org/10.1017/s0967199405003059.

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Aurora-A is a serine/threonine protein kinase that plays important regulatory roles during mitotic cell cycle progression. In this study, Aurora-A expression, subcellular localization, and possible functions during porcine oocyte meiotic maturation, fertilization and early embryonic cleavage were studied by using Western blot, confocal microscopy and drug treatments. The quantity of Aurora-A protein remained stable during porcine oocyte meiotic maturation. Confocal microscopy revealed that Aurora-A distributed abundantly in the nucleus at the germinal vesicle stage. After germinal vesicle breakdown, Aurora-A concentrated around the condensed chromosomes and the metaphase I spindle, and finally, Aurora-A was associated with spindle poles during the formation of the metaphase II spindle. Aurora-A concentrated in the pronuclei in fertilized eggs. Aurora-A was not found in the spindle region when colchicine or staurosporine was used to inhibit microtubule organization, while it accumulated as several dots in the cytoplasm after taxol treatment. In conclusion, Aurora-A may be a multifunctional kinase that plays pivotal regulatory roles in microtubule assembly during porcine oocyte meiotic maturation, fertilization and early embryonic mitosis.
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49

Schmid, Ingrid, Isabel Sattler, Susanne Grabley, and Ralf Thiericke. "Natural Products in High Throughput Screening: Automated High-Quality Sample Preparation." Journal of Biomolecular Screening 4, no. 1 (1999): 15–25. http://dx.doi.org/10.1177/108705719900400104.

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At present, compound libraries from combinatorial chemistry are the major source for high throughput screening (HTS) programs in drug discovery. On the other hand, nature has been proven to be an outstanding source for new and innovative drugs. Secondary metabolites from plants, animals, and microorganisms show a striking structural diversity that supplements chemically synthesized compounds or libraries in drug discovery programs. Unfortunately, extracts from natural sources are usually complex mixtures of compounds, often generated in time-consuming and, for the most part, manual processes. Because quality and quantity of the provided samples play a pivotal role in the success of HTS programs, this poses serious problems. In order to make samples of natural origin competitive with synthetic compound libraries, we devised a novel, automated sample preparation procedure based on solid-phase extraction (SPE). By making use of modified Zymark (Hopkinton, MA) RapidTrace® SPE workstations, we developed an easy-to-handle and effective fractionation method that generates high-quality samples from natural origin, fulfilling the requirements for an integration in high throughput drug discovery programs.
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50

Buja, Ilaria, Erika Sabella, Anna Grazia Monteduro, et al. "Advances in Plant Disease Detection and Monitoring: From Traditional Assays to In-Field Diagnostics." Sensors 21, no. 6 (2021): 2129. http://dx.doi.org/10.3390/s21062129.

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Human activities significantly contribute to worldwide spread of phytopathological adversities. Pathogen-related food losses are today responsible for a reduction in quantity and quality of yield and decrease value and financial returns. As a result, “early detection” in combination with “fast, accurate, and cheap” diagnostics have also become the new mantra in plant pathology, especially for emerging diseases or challenging pathogens that spread thanks to asymptomatic individuals with subtle initial symptoms but are then difficult to face. Furthermore, in a globalized market sensitive to epidemics, innovative tools suitable for field-use represent the new frontier with respect to diagnostic laboratories, ensuring that the instruments and techniques used are suitable for the operational contexts. In this framework, portable systems and interconnection with Internet of Things (IoT) play a pivotal role. Here we review innovative diagnostic methods based on nanotechnologies and new perspectives concerning information and communication technology (ICT) in agriculture, resulting in an improvement in agricultural and rural development and in the ability to revolutionize the concept of “preventive actions”, making the difference in fighting against phytopathogens, all over the world.
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