Relevant bibliographies by topics / Placenta and rats

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers

Academic literature on the topic 'Placenta and rats'

Author: Grafiati
Published: 4 June 2021
Last updated: 6 February 2022

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Journal articles on the topic "Placenta and rats"

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Martínez, N., E. Capobianco, V. White, M. C. Pustovrh, R. Higa та A. Jawerbaum. "Peroxisome proliferator-activated receptor α activation regulates lipid metabolism in the feto-placental unit from diabetic rats". REPRODUCTION 136, № 1 (2008): 95–103. http://dx.doi.org/10.1530/rep-08-0028.

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Maternal diabetes promotes an overaccumulation of lipids in the feto-placental unit and impairs feto-placental development and growth. Here, we investigated the role played by the nuclear receptor peroxisome proliferator-activated receptor (PPAR)α in lipid metabolism in fetuses and placentas from control and neonatal streptozotocin-induced diabetic rats. Placentas and fetuses were studied on day 13.5 of gestation. The concentrations of PPARα (by Western blot) and its endogenous agonist leukotriene B4 (LTB4) (by enzyme immunoassay) were analysed. Placental explants and fetuses were cultured wit
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Reyes-Hernández, Cynthia, David Ramiro-Cortijo, Pilar Rodríguez-Rodríguez, et al. "Effects of Arachidonic and Docosohexahenoic Acid Supplementation during Gestation in Rats. Implication of Placental Oxidative Stress." International Journal of Molecular Sciences 19, no. 12 (2018): 3863. http://dx.doi.org/10.3390/ijms19123863.

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Arachidonic and docosahexaenoic acids (ARA and DHA) are important during pregnancy. However, the effects of dietary supplementation on fetal growth and oxidative stress are inconclusive. We aimed to assess the effect of high ARA and DHA diet during rat gestation on: (1) ARA and DHA availability in plasma and placenta, (2) fetal growth, and (3) placental oxidative stress, analyzing the influence of sex. Experimental diet (ED) was prepared by substituting soybean oil in the control diet (CD) by a fungi/algae-based oil containing ARA and DHA (2:1). Rats were fed with CD or ED during gestation; pl
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Dehghani, Leila, Hedayat Sahraei, Rokhsareh Meamar, and Masoomeh Kazemi. "Time-Dependent Effect of Oral Morphine Consumption on the Development of Cytotrophoblast and Syncytiotrophoblast Cells of the Placental Layers during the Three Different Periods of Pregnancy in Wistar Rats." Clinical and Developmental Immunology 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/974205.

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Previous studies have shown that morphine abuse during pregnancy cancause a delay in the development of the placenta and embryo and also bring about birth defects. The present study investigates the effect of the duration of maternal morphine consumption during pregnancy, as well as the impacts of morphine abuse on the development of placental layers during the three different periods of pregnancy in Wistar rats.Materials and Methodology. Female Wistar rats have been used in the present study. Experimental groups received morphine (0.05 mg/mL of drinking water) after one night of coupling with
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Pustovrh, M. C., A. Jawerbaum, V. White, et al. "The role of nitric oxide on matrix metalloproteinase 2 (MMP2) and MMP9 in placenta and fetus from diabetic rats." Reproduction 134, no. 4 (2007): 605–13. http://dx.doi.org/10.1530/rep-06-0267.

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Matrix metalloproteinases (MMPs) play an important role in tissue remodeling that accompanies the rapid growth, differentiation, and structural changes of the placenta and several fetal organs. In the present study, we investigated whether the diabetic maternal environment may alter the regulatory homeostasis exerted by nitric oxide (NO) on MMPs activity in the feto-placental unit from rats at midgestation. We found that NADPH-diaphorase activity, which reflects the distribution and activity of NO synthases (NOS), was increased in both placenta and fetuses from diabetic rats when compared with
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El-din, Eman Y. Salah, and Amel R. Omar. "EFFECT OF PRENATAL ADMINISTRATION OF THERAPEUTIC DOSE OF TOPIRAMATE ON PLACENTAE ALBINO RATS' FETUSES." International Journal of Pharmacy and Pharmaceutical Sciences 9, no. 3 (2017): 54. http://dx.doi.org/10.22159/ijpps.2017v9i3.16208.

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Objective: Topiramate is an antiepileptic drug (AED) used for the treatment of partial seizure in adult and children epileptic patients. It passed through the placenta causing a birth defect. However, little literature focused on placental alteration due to the administration of topiramate during pregnancy. So, applying different predictive parameters; placental weight, histopathological (Haematoxylin and Eosin), histochemical (periodic acid Schiff’s) and immunohistochemistry (Caspase-3).Methods: Topiramate was orally administrated to the pregnant rats with dose 100 mg/kg rats from 5th to 19th
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Achur, Rajeshwara N., Sean T. Agbor-Enoh, and D. Channe Gowda. "Rat Spongiotrophoblast-specific Protein Is Predominantly a Unique Low Sulfated Chondroitin Sulfate Proteoglycan." Journal of Biological Chemistry 281, no. 43 (2006): 32327–34. http://dx.doi.org/10.1074/jbc.m605841200.

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We have previously demonstrated that the human placenta contains a uniquely low sulfated extracellular aggrecan family chondroitin sulfate proteoglycan (CSPG). This CSPG is a major receptor for the adherence of Plasmodium falciparum-infected red blood cells (IRBCs) in placentas, causing pregnancy-specific malaria. However, it is not known whether such low sulfated CSPGs occur in placentas of other animals and, if so, whether IRBCs bind to those CSPGs. In this study, we show that rat placenta contains a uniquely low sulfated extracellular CSPG bearing chondroitin sulfate (CS) chains, which comp
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Thomas, Chris R., Beryl B. Oon, and Clara Lowy. "Placental Transfer of Lactate, Glucose and 2-deoxyglucose in Control and Diabetic Wistar Rats." International Journal of Experimental Diabetes Research 2, no. 2 (2001): 113–20. http://dx.doi.org/10.1155/edr.2001.113.

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Placental transfer of lactate, glucose and 2-deoxyglucose was examined employing thein situperfused placenta. Control and streptozotocin induced diabetic Wistar rats were infused with U-14C]-glucose and [3H]-2-deoxyglucose (2DG). The fetal side of the placenta was perfuseci with a cell free medium and glucose uptake was calculated in the adjacent fetuses. Despite the 5-fold higher maternal plasma glucose concentration in the diabetic dams the calculated fetal glucose metabolic index was not significantly different between the 2 groups. Placental blood flow was reduced in the diabetic animals c
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Capobianco, E., A. Jawerbaum, M. C. Romanini та ін. "15-Deoxy-Δ12,14-prostaglandin J2 and peroxisome proliferator-activated receptor γ (PPARγ) levels in term placental tissues from control and diabetic rats: modulatory effects of a PPARγ agonist on nitridergic and lipid placental metabolism". Reproduction, Fertility and Development 17, № 4 (2005): 423. http://dx.doi.org/10.1071/rd04067.

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15-Deoxy-Δ12,14-prostaglandin J2 (15dPGJ2) is a peroxisome proliferator-activated receptor γ (PPARγ) ligand that regulates lipid homeostasis and has anti-inflammatory properties in many cell types. We postulated that 15dPGJ2 may regulate lipid homeostasis and nitric oxide (NO) levels in term placental tissues and that alterations in these pathways may be involved in diabetes-induced placental derangements. In the present study, we observed that, in term placental tissues from streptozotocin-induced diabetic rats, 15dPGJ2 concentrations were decreased (83%) and immunostaining for nitrotyrosine,
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Prokopyuk, V., O. Chub, M. Shevchenko, and O. Prokopyuk. "Placental stem cells, organotypic culture and human placenta extract have neuroprotective activity in vitro." Cell and Organ Transplantology 5, no. 1 (2017): 39–42. http://dx.doi.org/10.22494/cot.v5i1.67.

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According to WHO, 6.7 million people die from stroke every year. The search for new neuroprotective substances remains an urgent task.The purpose of this study was to investigate the neuroprotective activity of factors of placental origin.Materials and methods. Neuroprotective activity of media conditioned with cryopreserved placenta derived mesenchymal stem cells (MSCs), organotypic culture of placenta and placental extract was studied on in vitro models of glutamate excitotoxicity in rats` neural cells. Neural cells were cultured with placental factors without glutamate treatment, before and
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Mayeur, Sylvain, Steve Lancel, Nicolas Theys, et al. "Maternal calorie restriction modulates placental mitochondrial biogenesis and bioenergetic efficiency: putative involvement in fetoplacental growth defects in rats." American Journal of Physiology-Endocrinology and Metabolism 304, no. 1 (2013): E14—E22. http://dx.doi.org/10.1152/ajpendo.00332.2012.

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Low birth weight is associated with an increased risk for developing type 2 diabetes and metabolic diseases. The placental capacity to supply nutrients and oxygen to the fetus represents the main determiner of fetal growth. However, few studies have investigated the effects of maternal diet on the placenta. We explored placental adaptive proteomic processes implicated in response to maternal undernutrition. Rat term placentas from 70% food-restricted (FR30) mothers were used for a proteomic screen. Placental mitochondrial functions were evaluated using molecular and functional approaches, and
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Dissertations / Theses on the topic "Placenta and rats"

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Matos, Marcelo Alexandre de. "Efeitos do ciclamato de sódio na placenta de ratas: estudo morfométrico." Faculdade de Medicina de São José do Rio Preto, 2006. http://bdtd.famerp.br/handle/tede/8.

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Made available in DSpace on 2016-01-26T12:51:10Z (GMT). No. of bitstreams: 1 marceloalexandrematos_dissert.pdf: 295732 bytes, checksum: b602897faf078224a99d93671326e504 (MD5) Previous issue date: 2006-05-24<br>Objective: To evaluate the effects of sodium cyclamate on the rat placenta by its administration in the period of embryogenesis. Method: The sodium cyclamate was administered by intraperitoneal route in rats of the treated group at the dose of 60 mg/kg, from the tenth to fourteenth day of gestation, while the equivalent volume of saline solution was given to the control group, by th
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Lippi, Luciana Lucinio. "Estudo da toxicidade da Ipomoea carnea em ratas durante o período perinatal. Avaliação dos possíveis efeitos lesivos no tecido placentário." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/10/10133/tde-17122009-173640/.

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A Ipomoea carnea é uma planta tóxica amplamente distribuída no Brasil e em outros países tropicais. Durante os períodos de seca esta planta se mantém verde, podendo servir como fonte de alimento para os animais de produção. A intoxicação natural é de caráter crônico e ocorre quando ruminantes particularmente, caprinos ingerem a planta, estes animais desenvolvem, principalmente, sintomatologia de origem nervosa. Dois tipos de princípios ativos tóxicos foram isolados desta planta, um alcalóide nortropânico, as calisteginas B1, B2, B3 e C1 e principalmente o alcalóide indolizidínico, a suainsonin
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Weis, Simone Nardin. "Efeitos de compostos orgânicos de selênio sobre o desenvolvimento intra-uterino da prole de ratas wistar." Universidade Federal de Santa Maria, 2007. http://repositorio.ufsm.br/handle/1/11081.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>Selenium (Se) is an essential trace element for man and is known for its role in regulating growth and development of the fetus and newborn. It is well known that Se deficiency is related to miscarriages and pre-term deliveries. However, it is established that Se compounds, depending of dose, can be highly toxic to several species of animals. The organoselenium compounds, diphenyl diselenide [(PhSe)2] and 3 3- ditrifluoromethyldiphenyl diselenide [(F3CPhSe)2] were the target of this study since they present important pharmacologi
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Leandro, Sandra Márcia. "Sobrecarga e restrição de sal na dieta durante a gestação em ratas Wistar: efeitos sobre o sistema renina-angiotensina, função renal, resistência à insulina e pressão arterial." Universidade de São Paulo, 2006. http://www.teses.usp.br/teses/disponiveis/5/5148/tde-08012007-172716/.

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Diversos estudos epidemiológicos têm relacionado doenças na vida adulta, como diabetes tipo-2 e hipertensão, e ambiente inadequado durante a vida fetal. Fatores distintos relacionados aos hábitos alimentares, como ingestão de sal na dieta, podem ter impacto importante no período perinatal. Recentemente, demonstramos que dieta hipossódica (HO) durante a gestação está associada com baixo peso ao nascimento e alterações na vida adulta. O objetivo do presente estudo foi avaliar o efeito da dieta HO e hipersódica (HR) durante gestação em ratas. Ratas Wistar foram alimentadas com dieta HO, dieta nor
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Possignolo, Luiz Fernando 1987. "Efeito da ingestão crônica de dieta hiperlipídica no metabolismo de ratas, e sobre a expressão de SR-BI e ABCA1 na placenta, intestino delgado, fígado e rins da prole destes animais = Effect of high fat diet chronic ingestion on the metabolism of female rats, and on the SR-BI and ABCA1 expression in the placenta, small intestine, liver and kidney of the offspring." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/309926.

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Orientador: José Antonio Rocha Gontijo<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas<br>Made available in DSpace on 2018-08-21T06:22:30Z (GMT). No. of bitstreams: 1 Possignolo_LuizFernando_M.pdf: 4767580 bytes, checksum: b843458e4c7049fc29741e4aca9f918d (MD5) Previous issue date: 2012<br>Resumo: Devido ao maior consumo de alimentos ricos em gordura e um estilo de vida mais sedentário, houve um aumento na incidência de desordens metabólicas relacionadas ao metabolismo lipídico como a resistência à insulina, dislipidemias, e sua associação com doe
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Soto, Sônia de Fátima. "Alterações placentárias em resposta à exposição de ratas Wistar à poluição atmosférica." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5148/tde-20052015-081635/.

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Introdução: A exposição à poluição atmosférica durante a gestação provoca alterações nas características da placenta e pode resultar em restrição de crescimento intrauterino. Sabe-se que o transforming growth factor beta 1 (TGFbeta1), o sistema renina-angiotensina uteroplacentário (SRA) e os fatores angiogênicos, tais como vascular endothelial growth factor A (VEGF-A) participam do processo de placentação e regulação do fluxo sanguíneo uteroplacentário. Assim, o objetivo do presente estudo foi investigar o efeito da exposição à poluição do ar sobre a morfologia, função e SRA placentários. Méto
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Buffat, Christophe. "Retard de croissance intra utérin et origine précoce des maladies de l'adulte : mécanismes physiopathologiques et moléculaires." Paris 7, 2008. http://www.theses.fr/2008PA077053.

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La restriction de croissance intra-uterine et une croissance postnatale trop rapide sont reconnues comme des facteurs de risques des maladies cardiovasculaires de l'adulte. Les mecanismes qui en sont responsable ne sont pas reellement connus. Au cours de ce travail de these, 2 approches ont ete suivies a l'aide d'un modele rat. La 1ere partie a pour but de caracteriser a l'aide de microarrays des alterations precoces de l'expression de genes du placenta et du rein de ratons hypotrophes. Une vue hierarchique des mecanismes regulant massivement des familles de genes modules ainsi qu'une regulati
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Freitas, Murilo Rodrigues Barbosa de. "O efeito do selênio em ratas Wistar prenhas infectadas pela cepa Y de Trypanosoma cruzi." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/60/60135/tde-31102014-102620/.

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O selênio (Se) é um micronutriente importante na dieta de mamíferos e tem sido descrito com importante papel na função imune. É constituinte de mais de 25 selenoproteínas na forma do aminoácido selenocisteína, sendo este elemento crítico na manutenção do sistema de defesa antioxidante. Uma dieta complementar com Se pode ser benéfica no tratamento de doenças correlacionadas com altos níveis de estresse oxidativo, como a doença de Chagas, enfermidade negligenciada causada por Trypanosoma cruzi. O objetivo deste estudo foi avaliar os efeitos do Se em ratas Wistar prenhas infectadas pela cepa Y de
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Robinson, N. R. "Calcium transfer across the rat placenta." Thesis, University of Manchester, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234186.

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Chura, Lindsay R. "The effect of chronic and acute maternal stress on expression of placental barrier genes in the rat /." Connect to online version, 2006. http://ada.mtholyoke.edu/setr/websrc/pdfs/mhc/2006/143.pdf.

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Books on the topic "Placenta and rats"

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Hudson, Lionel. The Rats of Rangoon: The inside story of the 'fiasco' that took placeat the end of the war in Burma. Arrow Bks., 1989.

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Palmer, Julie R. Choriocarcinoma. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190238667.003.0050.

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Gestational choriocarcinoma is an extremely rare cancer that occurs in women of childbearing age. The malignancy arises from the trophoblastic epithelium of the placenta, which is formed from embryonic tissue. Choriocarcinoma is one of several related gestational trophoblastic diseases, which include complete and partial hydatidiform mole, invasive mole, and the extremely rare placental site and epithelioid trophoblastic tumors. Because at least 50% of choriocarcinomas occur after a recognized hydatidiform mole, incidence patterns of the latter are of interest. The only established risk factor
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Rizzuto, Gabrielle A., and Anna I. Bakardjiev. Listeria monocytogenes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190604813.003.0020.

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Listeria monocytogenes is a intracellular bacterial pathogen that causes serious foodborne illness in humans. Among all infectious diseases caused by gastrointestinal pathogens, listeriosis has the highest mortality rate, likely because of its ability to cross the gastrointestinal barrier and cause sepsis and infection of other organs such as the brain and placenta. Infection of the placenta leads to fetal infection, and otherwise healthy pregnant women have a significantly increased incidence of listeriosis than the general population, likely due to changes in the maternal cell-mediated immun
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Book chapters on the topic "Placenta and rats"

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Masuda, Ryuichi, Michihiro C. Yoshida, and Motomichi Sasaki. "Chromosomal Mapping of the Placental Glutathione S-Transferase Gene and Its Expression in Livers of LEC Rats." In The LEC Rat. Springer Japan, 1991. http://dx.doi.org/10.1007/978-4-431-68153-3_37.

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Illsley, Nicholas P., S. Hall, and T. E. Stacey. "The Modulation of Glucose Transfer Across the Human Placenta by Intervillous Flow Rates: An In Vitro Perfusion Study." In Cellular Biology and Pharmacology of the Placenta. Springer US, 1987. http://dx.doi.org/10.1007/978-1-4757-1936-9_38.

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Hamlett, William C. "Ontogeny of the umbilical cord and placenta in the Atlantic sharpnose shark, Rhizoprionodon terraenovae." In The reproduction and development of sharks, skates, rays and ratfishes. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-3450-9_23.

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Wourms, John P. "Maximization of evolutionary trends for placental viviparity in the spadenose shark, Scoliodon laticaudus." In The reproduction and development of sharks, skates, rays and ratfishes. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-017-3450-9_24.

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Hazelhoff Roelfzema, W., A. M. Roelofsen, J. H. J. Copius Peereboom-Stegemann, and R. F. M. Herber. "ZINC AND CADMIUM CONCENTRATIONS IN LIVER AND PLACENTAS OF RATS: ARE THEY INTERRELATED?" In Proceedings of the 4. International Workshop, Neuherberg, F. R. G., April 1986, edited by Peter Brätter. De Gruyter, 1987. http://dx.doi.org/10.1515/9783111692449-025.

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Marrie, Thomas J. "Coxiella burnetii infections (Q fever)." In Oxford Textbook of Medicine, edited by Christopher P. Conlon. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198746690.003.0146.

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Q fever is a zoonosis caused by Coxiella burnetii, an intracellular Gram-negative spore-forming bacterium, the common animal reservoirs of which are cattle, sheep, and goats. Rats and mice have been implicated as reservoirs in some areas. In French Guiana the three-toed sloth is the reservoir. C. burnetti is trophic for the endometrium and mammary glands of female animals, and during pregnancy the organism reaches very high concentrations in the placenta such that at the time of parturition organisms are aerosolized and contamination of the environment occurs. Inhalation of even one microorganism can result in infection. Diagnosis is confirmed by serological testing: in acute disease antibodies to phase II antigen are higher than those to phase I, whereas the reverse is true in chronic disease.
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"Endocrine Disrupters." In Environmental Toxicology, edited by Sigmund F. Zakrzewski. Oxford University Press, 2002. http://dx.doi.org/10.1093/oso/9780195148114.003.0011.

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The first indications that hormonal imbalance during pregnancy may result in abnormal development of the fetus goes back to the 1930s. In 1939 researchers at Northwestern University Medical School reported that when pregnant rats were given an extra dose of external estrogen, the offspring suffered structural defects in their sex organs, both females and males (1) For years, this phenomenon was considered by the scientific and medical community as specifically related to rodents and thus did not concern humans. Furthermore, it had been generally believed that human placenta represented a barrier impenetrable by chemicals to which a pregnant woman was exposed. The myth of the placental barrier was shattered by the thalidomide tragedy. Thalidomide was developed in 1957 and found extensive use in Europe and Australia as a prescription drug to be used in pregnancy as a tranquilizer and against nausea. Soon, however, it had to be withdrawn from the market because some babies of women who took thalidomide were born highly deformed, lacking whole limbs or having underdeveloped limbs. Not all babies of women taking thalidomide suffered deformities There was no relationship between the total dose of the drug and the effect. Rather the effect depended on timing—on the time during the pregnancy during which the drug was taken. The deformities occurred only when thalidomide was taken during the organ-forming period—between the fifth and eighth week. Diethylstilbestrol (DES) was first synthesized as a synthetic estrogen-analog in 1943. In decades to follow it was widely prescribed to pregnant women for prevention of miscarriages. However, in 1952 an epidemiological study conducted at the University of Chicago indicated that there was no difference in the frequency of miscarriages between women who did not take DES and those that did take it. Despite this finding many physicians kept prescribing the drug through the 1960s. In 1971 two independent case-control epidemiological studies had shown that among girls born to women who took DES there was a high frequency of vaginal cancer occurring at unusually young age of 15 to 22 (2,3).
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Janssen, Matthew K., and Steven J. Ralston. "Maternal Morbidity Associated With Multiple Repeat Cesarean Deliveries." In 50 Studies Every Obstetrician-Gynecologist Should Know. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780190947088.003.0019.

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The article provides a review of a landmark study characterizing the risk of repeat cesarean deliveries. This multicenter prospective cohort study of over 30,000 cesarean deliveries demonstrates that risks of cesarean delivery increase sequentially, even in the absence of placenta accreta. The most dramatic increase is noted in the high rates of accreta with placenta previa and multiple cesarean deliveries, greater than 40% with 3 of more cesarean deliveries. This review highlights the key findings, methodology, and impact of this landmark study. It discusses other studies that continue to verify these results as well as contextualize them in the management of placenta accreta with developing centers of excellence. Finally, the article provides a sample clinical case scenario that applies the findings of this study.
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Westgate, Jenny. "Computerizing the Cardiotocogram (CTG)." In Medical Informatics in Obstetrics and Gynecology. IGI Global, 2009. http://dx.doi.org/10.4018/978-1-60566-078-3.ch010.

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During pregnancy the fetus requires an adequate supply of oxygen and clearance of carbon dioxide which is a waste product of metabolism. In fetal life, the placenta provides this function. After birth the lungs are aerated and perform this. If there is a failure to transport these chemicals across the placenta, the fetus can become hypoxic and acidotic, which can lead to permanent brain damage. In the neonate this can manifest in a number of ways, but most seriously cerebral palsy. Assessment of the fetal heart rate has been shown to identify fetuses where this maybe occurring. However the inter observer variation amongst clinicians assessing the heart rate monitoring is high and interpretation skills are often not good. Computer assessment of the fetal heart rate has been used and developed. Expert system techniques have been used to develop a system. The systems developed have been shown in studies to perform better than humans and to be able to identify subtleties not seen by the human eye. Future research is further assessing the value of these systems.
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Lobmaier, Silvia M., Karl-Theo M. Schneider, and Gerard H. A. Visser. "Heart Rate Changes and Autonomic Nervous System in Fetal Growth Restriction." In Placental-Fetal Growth Restriction. Cambridge University Press, 2018. http://dx.doi.org/10.1017/9781316181898.021.

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Conference papers on the topic "Placenta and rats"

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Cherkashova, Elvira, Veronika Burunova, Daria Namestnikova, et al. "THE EFFECTIVENESS AND DISTRIBUTION OF INTRAVENOUS TRANSPLANTATION OF MESENCHYMAL STEM CELLS DERIVED FROM HUMAN PLACENTA AND NEURAL PROGENITOR CELLS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS IN RATS WITH FOCAL CEREBRAL ISCHEMIA." In XVII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2021. http://dx.doi.org/10.29003/m2398.sudak.ns2021-17/417-418.

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Godal, H. C., F. Brosstad, and B. Holm. "CONGENITAL HYPOFIBRINOGENEMIA, DEEP VEIN THROMBOSIS AND RECURRENT PLACENTAL ABRUPTION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644279.

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A patient with hypofibrinogenemia, deep vein thrombosis and recurrent placental abruption is reported. The persistently low plasma fibrinogen concentration strongly suggested that the condition was inherited, and this was supported by low fibrinogen levels and thrombosis tendency in the patient's brother. The exact nature of the condition is not known, but the close agreement between the clottable and immunologic fibrinogen -indicates the presence of a hyperfibrinogenemia sensu stricte rather than dysfibrinogenemia, and this was supported by uniformly negative tests to detect fibrinogen abnorm
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3

Yadav, Sushma. "Unusual clinical presentation of chriocarcinoma in young patients – Neulological meatastasis." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685389.

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Introduction: Choriocarcinoma is a malignant trophoblastic tumor, usually of placenta and characterized by ‘early hematogenous spread’ to lungs. Choriocarcinoma of placenta is preceded by – H. Mole (50%), spontaneous abortion (20%), ectopic pregnancy (2%) and normal term pregnancy (20%-30%). It is chemosensitive tumor and even in metastatic lesion cure rate is 90%-95%. Most common site of metastasis is lung and vagina, vulva, kidney, liver, ovaries, brain and intestine. If tumor is not diagnosed and managed timely, because of its vascularity, it bleeds profusely leading to death. Cases: We enc
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Novell, Anthony, Vanda Mendes, Arthuis Chloe, Ayache Bouakaz, and Franck Perrotin. "Notice of Removal: Evaluation of utero-placental perfusion in intrauterine growth restriction rat model using CEUS." In 2017 IEEE International Ultrasonics Symposium (IUS). IEEE, 2017. http://dx.doi.org/10.1109/ultsym.2017.8092965.

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Philips, M., A. G. Juul, S. Thorsen, J. Selmer, and L. Thim. "PURIFICATION AND CHARACTERIZATION OF REACTIVE AND NON-REACTIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) FROM HUMAN PLACENTA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642806.

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Reactive and non-reactive forms of PAI-1 have been identified in various biological materials. The structural differences between these forms remain to be determined.A monoclonal antibody specific for a non-reactive PAI-1 and a monoclonal antibody reacting with both the reactive and nonreactive form of the inhibitor were obtained by immunization with a tissue-type plasminogen activator (t-PA)-PAI-1 complex (Philips et al., Thromb Haemostas 1986; 55:213-7). These antibodies were used for the isolation of reactive and non-reactive PAI-1 by solid-phase immunoadsorption from extracts of human plac
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Bajaj, Kanika. "Poster Abstract." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685361.

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Tuberous sclerosis (TS) is a genetic disorder that is inherited in an autosomal dominant fashion with variable clinical manifestations including seizures, mental retardation, renal failure and pneumothorax. The literature on TS in pregnancy is largely based upon case reports which have shown a 43% complication rate including oligohydramnios, polyhydramnios, IUGR, hemorrhage from ruptured renal tumors, PPROM, renal failure, placental abruption and perinatal demise. We reporting a case of 33 yr old female with gravida 3 para 2 and live 2 with period of gestation 9 months with tuberous sclerosis,
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Francis, C. W., and V. J. Marder. "RAPID FORMATION OF LARGE MOLECULAR WEIGHT O-P0LYMERS IN CROSSLINKED FIBRIN INDUCED BY HIGH FACTOR XIII CONCENTRATIONS: ROLE OF PLATELET FACTOR XIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643311.

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Following fibrin polymerization, activated factor XIII stabilizes the clot by catalyzing the formation of specific intermolecular covalent crosslinks between pairs of y chains to form dimers and also among two or more a chains to form polymers. We have identified a series of previously uncharacterized a chain polymers with a wide range of sizes, including some with apparent Mr in excess of several million. Additionally, we establish the role of high concentrations of factor XIII in the extent and rate of α-polymer formation and provide evidence that the factor XIII required can be provided by
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8

Giddings, J. C. "AN IMMUNORADIOMETRIC ASSAY (IRMA) FOR HUMANTHROMBOMODULIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643963.

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Thrombomodulin was separated from detergent-soluble fractions of human placenta using a combination of DEAE-Sepharose and thrombin-Sepharose chromatography. The final product demonstrated one major band (Mr approximately 100000) and three minor bands (Mr 40000 - 80000) on SDS-polyacrylamide gel electrophoresis. The purified protein markedly enhanced the rate of activation of human protein C by thrombin in the presence of calcium ions. Polyclonal antibodies to the isolated thrombomodulin were raised in rabbits and were shown to inhibit thrombin co-factor activity. Immunofluorescence of fibrobla
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Rákóczi, I., Gy Geró, J. Demeter, and I. Gáti. "INFLUENCE OF GLUCOSE AND INSULIN OF PROSTACYCLIN SYNTHESIS IN CULTURED TR0PH0BLAST CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643373.

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It is known that placental cells can produce prostacyclin /PGI2/. At present, the physiological role of trophoblast PGI2 production can only be speculative. PGI2 produced by trophoblast may help to prevent the platelet aggregation and thrombosis in spiral arteries and it can also explain the maintance of, and blood flow through, the spiral arteries during endovascular trophoblast invasion in early pregnancy. It has been previously shown that increased glucose concentrations in the incubation fluid can inhibit the formation of PGI2 by rat aortic rings. The aim of present investigation was to st
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Kruithof, E. KO, W. D. Schleuning, and F. Bachman. "PLASMINOGEN ACTIVATOR INHIBITOR BIOCHEMICAL AND CLINICAL ASPECTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644764.

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Plasminogen activator (PAs) are enzymes that convert the zymogen plasminogen into the trypsin-like protease plasmin, which degrades extracellular matrix proteins and fibrin in the course of fibrinolysis, embryogenesis, tissue remodeling and in tumor metastasis. Plasminogen activator inhibitors (PAIs) are important modulators of PA activity. Several proteins have been identified which inhibit at fast rates urokinase (u-PA) and tissue-type PA (t-PA). In the order of inhibition rate constants these are: a) PAI-1, present in human plasma and platelet extracts and purified from human endothelial ce
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