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1

Nasti, Jacquelyn. "Dancing Plague." ScholarWorks@UNO, 2018. https://scholarworks.uno.edu/td/2479.

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2

Raynolds, Nicholas. "the emotional plague." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/etd/3773.

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The artist discusses his Master of Fine Arts thesis exhibition “the emotional plague” held at the Reese Museum in Johnson City, Tennessee from March 2nd through March 27th, 2020 in which he examines a number of literary and invented narrative subjects influenced by science fiction, Surrealism and the current political climate in an attempt to reconcile the social and the personal through the creative act. Largely improvisational in their conception, the paintings and drawings in this exhibition reflect ideas derived from writers, thinkers and artists including Wilhelm Reich, J.G. Ballard, W.S. Burroughs and Goya, all distilled through the uncertain territory of Raynolds’ personal, internal landscape. He utilizes an amalgam of characters, tropes, and stories as metaphorical expressions of social psychosis and decay.
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3

Malek, Maliya Alia. "Plague in Maghreb." Thesis, Aix-Marseille, 2016. http://www.theses.fr/2016AIXM5021/document.

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Yersinia pestis, agent causal de la peste, persiste dans la nature maintenu par un cycle enzootique dans des foyers conduisant à la réémergence de la maladie. En Afrique du Nord, où une réémergence a eu lieu après des années de ‘silence’, nous avons répertorié les différents épisodes ainsi que le nombre de cas en sur six pays à compter de 1940 en mettant en évidence l’importation de la maladie et un mode de contamination négligé, la transmission par voie orale. Une étude en Algérie sur 237 micromammifères confirme deux foyers et en revèle trois nouveaux porteurs d’un nouveau génotype (MST) de biotype Orientalis. Apodemus sylvaticus est par la même ajouté à la liste des rongeurs pestiférés. La projection des foyers de peste ainsi actualisés sur une carte géographique et écologique met en évidence la proximité des foyers de peste aux points d’eau saumâtre. Une étude statistique a confirmé une corrélation significative entre foyer de peste/eau salée à une proximité minimale &lt;3 km en comparaison à des zones d’eau douce. Des échantillons environnementaux salés ont permis l’isolement d’une souche Y. pestis Algeria 3. Cette découverte confortée par l’observation expérimentale de la résistance de Y. pestis à un milieu hyper salé à 150g/L NaCl se traduisant par un protéome spécifique en réponse à ce stress avec une forme d’adaptation de type forme L de la bactérie dans ce type d’environnement. Notre travail éclaire de façon originale un facteur méconnu de persistance tellurique de Y. pestis, conditionnant la réémergence de la peste dans des foyers séculaires au Maghreb contrairement aux rivages Nord de la Méditerranée où la peste autochtone a disparu depuis un siècle<br>Yersinia pestis, the causal agent of plague, persists in nature maintained by an enzootic cycle in foci leading to the re-emergence of the disease. In North Africa, where re-emergence took place after years of 'silence', we have listed the various episodes and the number of cases in six countries from 1940 onwards, highlighting the importation of the disease and A method of neglected contamination, oral transmission. A study in Algeria on 237 micromammals confirms two foci and reveals three new carriers of a new genotype (MST) of orientalis biotype. Apodemus sylvaticus is by the same added to the list of plague rodents. The projection of the plague foci thus updated on a geographical and ecological map highlights the proximity of plague foci to brackish water points. A statistical study confirmed a significant correlation between plague / salt water at a minimal proximity &lt;3 km compared to freshwater areas. Saline environmental samples allowed the isolation of a Y. pestis Algeria 3 strain. This discovery was confirmed by the experimental observation of the resistance of Y. pestis to a hyper-saline medium at 150 g / L NaCl resulting in a specific proteome In response to this stress with an adaptation form of form L of the bacterium in this type of environment. Our work illuminates in an original way an unknown factor of telluric persistence of Y. pestis, conditioning the re-emergence of the plague in secular centers in the Maghreb unlike the northern shores of the Mediterranean where the indigenous plague has disappeared for a century
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4

Williamson, Masen J. "Thucydides' Plague, a Narrative Aggressor." BYU ScholarsArchive, 2021. https://scholarsarchive.byu.edu/etd/8884.

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This thesis expands upon the notion that Thucydides’ plague narrative in his History of the Peloponnesian War punctuates his argument for the unique greatness of the Peloponnesian War. Through the plague, Thucydides displays the collapse of Greek society’s standards and practices. He does this by describing a plague which does not conform to 5th century BCE Greek medical ideas. Balance, human art, and divine intervention all fail in their attempts to restore the health of the individual and society. Thucydides portrays the plague as a narrative aggressor whose intent is to topple Athens and its ideals. Lucretius’ plague narrative, because it narrates the same historical moment but from a different perspective, is then discussed in order to demonstrate how other authors have used Thucydides’ technique.
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5

Ast, Bernard Edward Jr 1963. ""The Plague" in Albert Camus's fiction." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/288839.

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This dissertation catalogues and examines Albert Camus's thematic repetitiveness as seen in his fiction and in how this repetitiveness relates to the world view presented in the so-called guillotine passage in his novel The Plague: that the world consists of scourges, victims, and an elusive third domain. A scourge can be an aggressor. It causes suffering and even death. The plague and other infirmities, both physical and mental, are aggressors. They are indiscriminate, merciless, and oftentimes deadly. Tyrants, too, are aggressors, some of which cling to the arbitrary, while others have a considerably more formal agenda. An aggressor can be metaphysical: the inner plague. Some aggressors, Like poverty and the climate, can also have a positive side to them. A scourge can also be an aggression--what the aggressor causes. They usually cannot be justified (existential separation, death, murder, execution, suicide), but some aggressions lead to enlightenment or positive change (exile, imprisonment, separation from loved ones). Yet one aggression, solitude of a certain kind, can actually be a desired and pleasant experience. Victims are the second domain. Camus focuses primarily on children, artists, clergy, judges and lawyers. The first three groups are presented in a balanced fashion, with emphasis on both the positive and the negative. Judges and lawyers are presented in a negative light, with only slight deviations. The third domain consists of true doctors (true friends) and peace/happiness, with true doctors--who are not necessarily doctors--contributing to the attainment of happiness or at least an improvement in circumstances. Light, the sea, other aspects of nature and sensual pleasures can also contribute to finding peace/happiness.
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6

Zhou, Hongxing. "Work methods and procedures for plague surveillance and control in South Africa." Thesis, Nelson Mandela Metropolitan University, 2006. http://hdl.handle.net/10948/649.

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Plague is a classic zoonosis caused by the bacterium Yersinia pestis and is subject to the International Health Regulations, 1969. In the last two millennia, plague has become widespread, with three pandemics occurring in the 6th, 14th and 20th centuries. Currently, plague outbreaks and epidemics still occur worldwide. This study attempts to develop formal work methods and procedures for plague surveillance and control by environmental health practitioners as a strategy to ensure that field data can be integrated within the municipal, provincial and national spheres of government. A qualitative, explorative, descriptive, inductive and deductive research design was followed. A documentary research approach was employed as the primary method of data collection. To obtain additional information, both semi-structured personal interviews and physical observations during plague surveillance were adopted by the researcher. The organisational structure of the health care system in South Africa was analysed to identify and explain the role and functions of relevant decision-makers related to the surveillance and control of plague within the different spheres of government. Legislative measures regarding plague surveillance and control were also presented. As a prerequisite for the development of work methods and procedures for plague surveillance and control, the epidemiology of plague was discussed with emphasis on the distribution and characteristics of the disease in South Africa. Important rodent reservoirs and flea vectors of plague in South Africa were identified. Clinical manifestations, diagnosis and treatment of plague were described and discussed. Within this qualitative study an attempt has been made to develop work methods (xiii) and procedures for plague surveillance and control in South Africa. Relevant field data forms to be used during plague surveillance and control strategies were also developed. Recommendations emanating from the study can be found in the final chapter.
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7

Truter, Elsie. "Plague in the Graeco-Roman world, 430 B.C.-A.D. 600." Master's thesis, University of Cape Town, 1988. http://hdl.handle.net/11427/17682.

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Bibliography: pages 115-125.<br>This dissertation concerns itself with the study of epidemics between 430 B.C. - A.D. 600, in an attempt to find positive evidence for the existence of bubonic plague in the ancient world. Most major studies on the Black Death have concerned themselves with the great pandemics of the Middle Ages and none (to my knowledge), have systematically examined the ancient records for earlier evidence of the disease. The time period chosen for this study, from the Athenian Plague to the Plague of Justinian, contains some relatively well documented epidemics, which has made it possible, in some cases, to identify the disease. Plague is a complicated disease, dependent on numerous factors for its successful spread, but few historians have considered this. The word 'plague' was loosely used in ancient texts to denote any epidemic disease with a high mortality rate and not a specific microbial infection. Most historians however translate 'plague' as bubonic plague and make no attempt at a medical analysis of the symptoms given by a particular author. The point of this dissertation is to examine the ancient epidemics from a medical as well as a historical angle. Our evidence for the existence of epidemic diseases comes from a variety of sources, and these are examined. Sculptures and frescoes show numerous chronic and acute disorders. Human remains have shown evidence of certain diseases, while animal and parasitic remains have helped to confirm the existence of certain species instrumental in the spread of a specific disease. However, written texts are the most reliable source for obtaining a detailed account of the symptoms and accurate interpretation of these texts is therefore important. To achieve this, the symptoms mentioned by an ancient author are compared and contrasted, through the use of tables, with the symptoms of some of the known infectious diseases of today. This dissertation will show that epidemics which were previously labelled plague could either not be identified as such, or were misdiagnosed. Evidence does point to the existence of bubonic plague in the ancient world, but it never reached epidemic proportions until A.D. 600.
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8

Clissold, Fiona J. (Fiona Jane) 1967. "Nutritional ecology of the Australian plague locust, Chortoicetes terminifera." Monash University, School of Biological Sciences, 2003. http://arrow.monash.edu.au/hdl/1959.1/5837.

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9

Cooke, Jennifer. "'But I ain't dead' : plague from Defoe to Romero." Thesis, University of Sussex, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.436394.

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10

Benedictow, Ole Jørgen. "Plague in the late medieval nordic countries : epidemiological studies /." Oslo : Middelalderforlaget, 1992. http://catalogue.bnf.fr/ark:/12148/cb35552740m.

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11

Leonard, Marie-Louise. "Plague epidemics and public health in Mantua, 1463-1577." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5704/.

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This thesis investigates how health officials sought to preserve or recover good health during plague epidemics in Mantua, from 1463-1577. Scholarship on health boards in Italy has focused primarily on larger cities such as Milan, Florence and Venice, while many smaller cities and states which formed part of the wider network of interdependent health offices have yet to receive significant attention. This study attempts to address this imbalance by focussing on Mantua, a hitherto neglected area in the heart of northern Italy. Historians have shown by the sixteenth century health offices had wide-ranging responsibilities, yet their most important function remained tackling plague outbreaks through measures including trade and travel bans, quarantine periods and lazaretti. An analysis of the Mantuan health office’s actions and reactions reveal that it does not fit neatly with the health board model historians have established elsewhere in northern and central Italy. I will argue that while the hallmarks of the ‘Italian system’ of public health procedures are evident, closer examination of their organisation and composition reveals that they were shaped by the incidence and severity of outbreaks. Above all, however, they were dependent upon and defined by the evolving state apparatus and by participation of the wider community, both lay and ecclesiastic. Contrary to the view that permanent Italian health offices enforced plague regulations uniformly, there was a degree of flexibility in application within the structures created to fight plague. Further, it will be argued that by examining in detail symbolic acts, such as processions, in conjunction with practical methods we see with greater clarity how civic and ecclesiastical authorities worked together in the attempt to restore the city to good health. By exploring the dialogues between civic authorities, the people they governed and interactions between specific health agencies across the peninsula, this thesis contributes to the understanding of the Gonzagan state-building process and concepts of public health in Renaissance Italy.
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12

Streeter, Richard Thomas. "Tephrochronology, landscape and population : impacts of plague on medieval Iceland." Thesis, University of Edinburgh, 2012. http://hdl.handle.net/1842/6181.

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This thesis examines the extent to which geomorphological change in sub-arctic landscapes may be driven by rapid declines in population over timescales of decades to centuries. Demographic decline driven by disease in pastoral agricultural systems is expected to alter patterns of land use. Using a chronology with 20 visible dated tephra layers from AD 870 to present, 2625 tephra layers were identified in 200 sediment profiles. Rates of sediment accumulation dated by tephra provide a record of erosion in Skaftártunga, South Iceland. The scale of enquiry is that of individual landholdings (5–10 km2) over decades to centuries; in order to tackle questions of resilience and change within coupled socio-ecological systems larger and smaller spatial scales (regions of 400 km2 and individual sediment profiles) and longer and shorter temporal scales (2.6 ka and years to decades) are also considered. The novel application of photogrammetric techniques to recording stratigraphic sections increases the frequency of measurement from tens to hundreds per stratigraphic unit and the resolution from ±2.5 mm to ±1 mm. This technique improves the accuracy of representative measures of sediment accumulation and their use in measuring landscape change. Two little known 15th century AD Grímsvötn tephras are mapped and dated to AD 1432±5 and AD 1457± 5 using sediment accumulation rates. A period of landscape stability from AD 1389–1597 is consistent with reduced grazing pressure due to population declines of more than 30% after plague in AD 1402–1404 and AD 1494. Climatic deterioration from AD 1450-1500 does not increase erosion as much as expected; this may be due to decreased grazing pressure after population decline in the 15th century. Increased erosion from AD 935–1262 is related to woodland clearance and increases in sediment accumulation post AD 1625 are related to climatic cooling during the Little Ice age and the migration of erosion fronts into deep lowland sediments.
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13

Frederick, Eva Charles Anna. "Plague of absence : insect declines and the fate of ecosystems." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/123783.

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Thesis: S.M. in Science Writing, Massachusetts Institute of Technology, Department of Comparative Media Studies/Writing, 2019<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 25-26).<br>In November of 2017, a group of researchers published a paper showing that since the 1980s, insect populations in protected areas in Germany have decreased by over 75 percent. The decline, dubbed by one reporter the "insect armageddon," was widespread, affecting sites on nature reserves across the country. It was also indiscriminate, affecting not just certain species, but overall biomass. In the following years, similar studies from Greenland, Puerto Rico, and locations in North America have also shown declines in number of insect species, abundance, and habitat. These declines have serious implications for ecosystems and for humans, some of which we can already see in effect, and some that scientists can't even predict to their full extent. This thesis will profile a research team in Costa Rica who are using caterpillar-parasitoid interactions to make estimates about insect population health, and explore the reasons for and extent of insect declines and their consequences for humans.<br>by Eva Charles Anna Frederick.<br>S.M. in Science Writing<br>S.M.inScienceWriting Massachusetts Institute of Technology, Department of Comparative Media Studies/Writing
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14

Campbell, Jason. "Responding to the Plague Years: AIDS Theatre in the 1980s." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1698.

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Acquired Immune Deficiency Syndrome (AIDS) was first discovered in 1981 and consequently changed United States history. Initially, it affected the gay community, and the United States Government did not actively combat the spread of the disease for the first four years of the epidemic. In response to a need for education, the theatre community took it upon itself to raise awareness about the disease. Artists such as Robert Chesley and Larry Kramer created pieces of theatre that helped society deal with AIDS. This thesis explores the AIDS theatre canon while focusing on two major works: Robert Chesley’s Night Sweat: A Romantic Comedy in Two Acts and Larry Kramer’s The Normal Heart. I also created a class on AIDS theatre that I taught in the fall semester of 2008 at Virginia Commonwealth University. Information on the process of teaching the class as well as the class outcome is also addressed.
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15

Rodgers, M. "The biology of crayfish plague (Aphanomyces astaci : Schikora) in Great Britain." Thesis, London Metropolitan University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233882.

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16

Kreppel, Katharina Sophia. "The effect of climate on the epidemiology of plague in Madagascar." Thesis, University of Liverpool, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.569175.

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Many infectious diseases of humans and animals are influenced by climate and changes in climate have an impact on future disease distribution and intensity. Understanding the processes involved is important to enable better disease prediction and effective prevention. The studies presented in this thesis aim to investigate the effects of climate on the epidemiology of plague in Madagascar. The influence of climate is explored from different angles aiming to fill some of the knowledge gaps still present in the understanding of the disease. The effect of large scale climate phenomena on inter-annual cycles of plague in Madagascar showed a change in the relationship between the El Nino Southern Oscillation the Indian Ocean Dipole and the plague incidence. To investigate the mechanisms by which climate affects the disease further, environmental variables associated with climate were examined for their effects on the spatial distribution of human plague cases in Madagascar. Altitude, vegetation cover and temperature were the main drivers identified when modelling human plague occurrence at the district level. An investigation into the micro-climate inside rat burrows, variations in flea vector abundance and vector species composition suggested that the climate in the highlands allows plague vectors, for the maintenance of the plague cycle, to be present in fairly high numbers throughout the year. A subsequent laboratory experiment obtained results on the effect of constant temperatures and humidity, as found in rodent burrows on the development stages of two plague vectors. Evidence for different climatic adaptations of the developmental stages of the species was found and development times and mortality rates differed significantly between species. X cheopis was far more successful under laboratory conditions than the endemic S. fonquerniei. However, changes in adult abundance recorded in the field did not reflect predicted changes in development rates estimated using findings from the laboratory study.
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17

Phoofolo, Pule. "In time of plague : the Basotho and the rinderpest, 1896-8." Thesis, Rhodes University, 2000. http://hdl.handle.net/10962/d1002405.

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Rinderpest, the most dreaded bovine plague, struck the cattle of the BaSotho in British Basutoland early in 1897. By December the murrain had spent itself, having reduced the cattle population by half As it did so, the rinderpest claimed the primary historical significance of an epidemic. By sharpening behaviour and illuminating latent or developing tendencies, the rinderpest helped to reveal the nooks and crannies of contemporary historical processes that would have otherwise eluded historical visibility. This thesis brings out the complexities and ambiguities surrounding the epidemic. It uses the crisis occasioned by the panzootic in its multifaceted manifestations as a prism through which we might view the complex aspects of contemporary historical processes. It goes beyond the narrow limits of the crisis itself to discerning the broader and wider historical patterns that the rinderpest helped to highlight.
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18

Muckart, Heather Diane. "The face of death : prints, personifications and the great plague of London." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/5103.

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This thesis examines a mass-produced broadsheet printed during the Great Plague of London (1664-1666), which unites the textual modes of poetry and medical prescription with imagery and statistical tabulation, titled Londons Lord Have Mercy Upon Us. The central woodcut on the broadsheet presents a view of London as a bounded expansion, and relegates the images of death, particularly registered in the personification of Death, to the outskirts of the city. This visual separation of the city from the plague sick (and the plague dead) is most profoundly registered on the border of the broadsheet, which is adorned with momento mori imagery. The ordered presentation of the plague city is likewise established in the mortality tabulations on the sheet. These tabulations, which were culled from the contemporaneous London Bills of Mortality, make visible the extent of the disease in the city, while simultaneously linking the plague to the poor London suburbs. Of particular interest are the representation of faces on the broadsheet – the face of the dead, the face of Death and the face of the city – and how these images relate to the plague orders imposed on the city population by the Corporation of London. These orders sought medically and legally to contain, and spatially to control, the larger social body of London through enacting a kind of erasure upon the identities of the sick and dead. These erasures registered themselves in material form as a kind of facelessness, a motif found on the figure of Death and in the skull-faces of the dead. This motif visually registers the various anxieties expressed towards the faces of the plague-sick by many contemporaries living in plague-London, an anxiety about those who visibly displayed the signs of their contagion and, more threatening still, about those who were asymptomatic. An increasing understanding of the plague as both visible and controllable in the early modern city of London was continuously being challenged by the conflicting belief that plague was a disease of invisible extension and manifestation. This variance is deeply registered in the ambiguous depiction of the plague-dead in the frame of the sheet.
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Chamberland, Celeste Catherine Marie. "Female healers and the boundaries of medical practice in post-plague England." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp04/mq25957.pdf.

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Hill, Taryn Nicole. "The American Plague: Milk Sickness and the Trans-Appalachian West, 1810-1930." OpenSIUC, 2014. https://opensiuc.lib.siu.edu/theses/1567.

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Milk sickness, attributed to a native plant called white snakeroot, was transmitted predominantly from cattle to humans via milk in the nineteenth- and twentieth-centuries in the states of Ohio, Indiana, Illinois, Missouri, Kentucky, and Tennessee, as well as in remote pockets of North Carolina. Milk sickness was responsible for many deaths throughout the region and is most commonly associated with the death of Nancy Hanks Lincoln, mother of President Abraham Lincoln. Milk sickness was more than an illness; it profoundly reshaped the landscape of an entire region, spawned a lesser-known regional conflict, and highlighted the question of what responsibilities were delegated to public officials as citizens were faced with looming environmental conditions that affected their mortality and economy.
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Ascenzo, Battistini Alessandra Milagros. "“Especies de Aphididae (Orden: Hemiptera) encontrados en cultivos en el distrito de Asia”." Bachelor's thesis, Universidad Ricardo Palma, 2016. http://cybertesis.urp.edu.pe/handle/urp/825.

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Los áfidos (Hemiptera: Aphididae) son insectos fitófagos, de tamaño pequeño, se pueden presentar en su forma alada o áptera, son considerados una plaga que afectan diversos cultivos agrícolas y ornamentales. Algunas especies pueden ser transmisores de virus que causan enfermedad en las plantas. Por lo general se encuentran en zonas tropicales. Este estudio nos ayudará a identificar las diversas especies de áfidos encontrados en cultivos del distrito de Asia, Cañete para poder ampliar el estudio de afidofauna peruana. Los áfidos de este trabajo se colectaron en plantas de interés económico y ornamental, tales como manzana, níspero, plátano, naranja, cucarda, hemerocallis, papiro, molle, tomate y granada. Se reportan nueve especies de àfidos en el distrito de Asia, Provincia de Cañete, Perú. Las especies fueron: Aphis craccivora,Aphis gossypii, Aphis nasturtii, Aphis spiraecola, Aphis punicae, Myzus hemerocallis, Pentalonia nigronervosa, Toxoptera aurantii y Schizaphis rotundiventris. Cuatro de ellas se registraron por primera vez para el distrito de Asia, Cañete, Aphis nasturtii, Aphis punicae, Pentalonia nigronervosa y Schizaphis rotundiventris.Aphids (Hemiptera: Aphididae) are phytophagous insects with small size, we can found them alate or apterous forms. The aphids are a pest that affect many crops. Some species could be virus transmitters that cause plants disease. This study could help us to identificate the diversity of aphid species founding in crops from Asia, Cañete so we can amplify the study of peruvian aphid fauna. Plants aphids of this study were collected in plants with economical and ornamental interest like apple, loquat, banana, orange, hibiscus, lily, papyro, molle, tomato and pomengranate. Nine species of aphids from Asia, Cañete in Peru are reported. The following species were: Aphis craccivora, Aphis gossypii, Aphis nasturtii, Aphis spiraecola, Aphis punicae, Myzus hemerocallis, Pentalonia nigronervosa, Toxoptera aurantii y Schizaphis rotundiventris. Four of them were registered for the first time in Asia, Cañete, Aphis nasturtii, Aphis punicae, Pentalonia nigronervosa y Schizaphis rotundiventris.
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Winzoski, Karen Jane. "A plague on both our houses, àCanada, the United States, and biological terrorism." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ64930.pdf.

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23

Thiagarajan, Bala. "Community dynamics of rodents, fleas and plague associated with black-tailed prairie dogs." Diss., Manhattan, Kan. : Kansas State University, 2006. http://hdl.handle.net/2097/246.

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24

Ayyadurai, Saravanan. "Specificity of the Yersinia Pestis biotype orientalis in the natural history of plague." Thesis, Aix-Marseille 2, 2010. http://www.theses.fr/2010AIX20674/document.

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Yesinia pestis est l'agent de la peste, maladie infectieuse spontanément mortelle, et une bactérie classée parmi les agents de bioterrorisme de groupe A [http://www.bt.cd.gov/agent/plague]. Les cas sporadiques ont été rapportés dans plusieurs pays d'Asie, d'Afrique, et d'Amérique et la peste reste endémique en Afrique (République Démocratique du Congo; Madagascar) qui déclare le plus grand nombre de cas annuels. La majorité de cas de peste chez les humains et les animaux sauvages se manifeste dans les régions délimitées géographiquement et appelées communément les foyers de la peste. Les mécanismes de la résistance de la peste dans le sol des foyers reste de nos jours un sujet de recherche alors que la peste est maintenant considérée comme une maladie re-émergente. Au cours de notre travail, nous avons développé un outil pour l'identification de Y. pestis par spectrométrie de masse MALDI-TOF MS. Cette méthode s'est avérée très simple et efficace pour l'identification au niveau des espèces, et constitue une méthode de première ligne d'identification. Nous avons ensuite montré que Y. pestis survivait et maintenait sa virulence pendant au moins neuf mois dans le sol stérilisé par la vapeur et humidifié, dépourvu d'éléments nutritifs ajoutés et d'invertébrés du sol. Afin de contribuer à l'étude de l'épidémiologie de la peste, nous avons démontré que seul le biovar Oriantalis est transmis dans un modèle animal par les poux d'homme (Pediculus humanus), les biovars Antiqua et Medievalis de Y. pestis n'étant pas transmissibles par les poux de corps. Le mécanisme impliqué dans la transmission de la peste par les poux de corps reste inconnu, ce qui voudrait dire que le mécanisme de l'adaptation de Y. pestis Orientalis à des nouveaux vecteurs qui sont corrélés aux circonstances de l'épidémie mortelle provoquée par la peste bubonique, reste aussi inconnu. Au cours d'un dernier travail, nous avons étudié des nouveaux composés pour la prophylaxie de la peste. Notamment, nous avons évalué le potentiel du lovastatine dans la prévention de la mortalité pendant la peste. Il a été démontré sur un modèle d'expérimentation avec les souris que la lovastatine réduisait considérablement le taux de mortalité associée à la peste. Toutes les données que nous avons rapportées dans ce rapport de thèse sont destinées à mieux comprendre le cycle épidémiologique de la peste<br>Yersinia pestis is the agent of deadly plague and a bacterium listed in the group A of potential bioterrorism agents [http://www.bt.cdc.gov/agent/plague/]. Sporadic cases are reported in several countries in Asia, Africa and America. Majority of human plague cases and enzootic animals occur in the geographical areas of so-called plague foci. The mechanisms sustaining geographical foci of plague remain poorly understood and plague been classified as a currently re-emerging disease. As first step, we established new front line tool for Y. pestis identification by using MALDI-TOF MS. This method was demonstrated to be simple and effective for Y. pestis identification at species level. Second step, we demonstrated that Y. pestis survived fully virulent for at least 9 months in a steam sterilized, humidified soil devoid of any nutritional supplements or any soil invertebrates. In third step we successfully demonstrated that the human louse (Pediculus humanus) as vector of plague and the body lice transmission of plague was restricted to Orientalis biovar; Antiqua and Medievalis biovars of Y. pestis were not able to transmit by body lice. This result shows that a un- explained mechanism is involved in the body lice transmission of plague and Y. pestis Orientalis adaptation to newly described vectors which effectively correlates the mass death caused by bubonic plague in Black Death individuals. Finally we conclude our study by exploring new compounds for the plague prophylaxis. The potential role of lovastatin in the prevention of mortality during plague was assessed. Lovastatin could significantly reduce the mortality associated with plague in an experimental mouse model. All These data herein we reported in our study may help to better understanding the epidemiology of plague
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Bubeck, Sarah S. "Mechanism by which Yersinia pestis blocks pro-inflammatory host responses : a dissertation /." San Antonio : UTHSC, 2007. http://proquest.umi.com/pqdweb?did=1394663471&sid=4&Fmt=2&clientId=70986&RQT=309&VName=PQD.

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26

Griffin, Kate Frances. "An investigation of the V antigen of Yersinia pestis as a potential vaccine antigen." Thesis, University of Newcastle Upon Tyne, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324934.

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Hardy, Nat Wayne. "Anatomy of pestilence, the satiric disgust of plague in early modern London, 1563-1625." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ59596.pdf.

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Verney, Susannah. "Panacea or plague : Greek political parties and accession to the European Community, 1974-1979." Thesis, King's College London (University of London), 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287853.

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Antonsen, Christopher W. "\"Its character shall not be destroyed\" : narrative, heritage, and tourism in the plague village /." The Ohio State University, 2001. http://rave.ohiolink.edu/etdc/view?acc_num=osu148639447597969.

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Ortega, Jessica. "Pestilence and prayer saints and the art of the plague in italy from 1370 - 1600." Honors in the Major Thesis, University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/594.

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Stemming from a lack of scholarship on minor plague saints, this study focuses on the saints that were invoked against the plague but did not receive the honorary title of plague patron. Patron saints are believed to transcend geographic limitations and are charged as the sole reliever of a human aliment or worry. Modern scholarship focuses on St. Sebastian and St. Roch, the two universal plague saints, but neglects other important saints invoked during the late Medieval and early Renaissance periods. After analyzing the reasons why St. Sebastian and St. Roch became the primary plague saints I noticed that other "minor" saints fell directly in line with the particular plague associations of either Sebastian or Roch. I categorized these saints as "second-tier" saints. This categorization, however, did not cover all the saints that periodically reoccurred in plague-themed artwork, I grouped them into one more category: the "third-tier" plague saints. This tier encompasses the saints that were invoked against the plague but do not have a direct association to the arrow and healing patterns seen in Sts. Sebastian and Roch iconographies. This thesis is highly interdisciplinary; literature, art, and history accounts were all used to determine plague saint status and grouping, but art was my foundation. I examined important works of art directly associated with the plague and noted which saints appeared multiple times. The results from that assessment spurred further hagiographic and literary study. It was clear that these saints had multivarient connections to the plague. This study into the lives of the saints reaffirms their placement in the artistic and religious history of the pestilential epidemic of the Medieval and early Renaissance periods.<br>B.A.<br>Bachelors<br>Arts and Humanities<br>Art History
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May, Madeline Adele. "The Passion of the Plague: The Representation of Suffering and Salvation in Art and Literature." Kent State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=kent1619453120236161.

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Burger, Andrew E. "A Modern Plague: U.S. Racial and Ethnic Vaccination Disparities During the 2009 H1N1 Influenza Pandemic." DigitalCommons@USU, 2018. https://digitalcommons.usu.edu/etd/7279.

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On June 11, 2009 the World Health Organization announced that a novel strain of H1N1 influenza was being classified a Phase 6 pandemic, the highest level of alarm indicating that the disease was present worldwide and its spread was inevitable. While seasonal influenza epidemics occur annually, the 2009 H1N1 strain was the first novel pandemic influenza since the 1968 Hong Kong flu. The 2009 H1N1 pandemic provides a case study of how the U.S. population responded to an emergent and potentially lethal infectious disease. The richness and variety of public health data presents an opportunity to examine predictors of vaccination among men and women from different racial/ethnic groups. Because vaccination is often the most effective way to prevent influenza, it is important to understand the predictors of low vaccination uptake during the H1N1 pandemic to better prepare for future novel outbreaks of influenza. Through a series of three research papers, my dissertation provides a comprehensive examination of the ways that race, ethnicity and gender affected H1N1 vaccination behavior. Paper 1 explores the diversity of the U.S. Hispanic population by estimating H1N1 vaccination uptake among U.S-born and foreign-born Hispanics. In Paper 2, I shift my focus to H1N1 vaccination disparities between non-Hispanic whites and non-Hispanic blacks in the U.S. This paper further explores racial disparities in vaccination by examining intersections with gender and analyzing the influence of attitudes and beliefs about the H1N1 vaccine. In Paper 3, I provide a more detailed account of the socioeconomic and attitudinal mechanisms through which race, ethnicity and gender influence H1N1 vaccination. My research confirms large racial/ethnic disparities in H1N1 vaccination and identifies mechanisms amenable to policy change that could reduce the disease burden of a future influenza pandemic.
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McKenzie, Linda M. "The Stereotypes and Biases That Plague Millennial Leaders| Best Practices and Strategies for Job Promotion." Thesis, Pepperdine University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10615236.

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<p> A dichotomy within U.S. organizations needs attention. Society has labeled millennials as a narcissistic people who have entitlement issues and lack the competencies necessary for globalization. Millennials are firing back with a desire for purposeful work. Meanwhile, the cohort is employed in the workforce with this stigma and experience challenges promoting into executive leadership roles. </p><p> The purpose of this study is to understand the challenges that millennials face being promoted to executive leadership roles. The literature review explored the top U.S. organizations to discover what sets them apart in distinction. The findings determined that the most successful organizations followed three guided principles of (a) investing heavily in people, (b) valuing diversity inclusion, and (c) providing guidance in holistic leadership practices that promote emotional literacy.</p><p> Fifteen millennial leaders were interviewed using a phenomenological methodology. Four research questions guided the study to address challenges, practices, strategies, measuring success, and recommendations. Findings from the study resulted in 849 characteristics and 58 themes.</p><p> Three overarching challenges in addition to three overarching consequential lived experiences were interpreted through the data. Millennial leaders used holistic learning strategies, authentic leadership characteristics and ethical leadership practices to overcome challenges. Growth, meaning, and value were the three overarching desires that measured their success. Three overarching leadership themes emerged that recommended future aspiring leaders be authentic, purposeful and virtuous. Indeed, the millennials will birth virtuous leadership practices in U.S. organizations (McKenzie, 2017).</p><p> The data revealed a series of personality traits and practices that coincide with the competency skills necessary for executive leadership and considered most important for success. Key findings discovered a common theme in the discussions on the benefits of feedback for leadership success. The crux of development for millennials is to resolve their definition of purpose and meaningful work, and then develop learning opportunities that support organizational outcomes. McKenzie (2017) postulates a T.E.A.M. (Teaching Empathy and Mindfulness) framework that uses the &ldquo;U&rdquo; and &ldquo;I&rdquo; in TEAM to facilitate purpose through positive psychology. The leadership model is guided by teaching empathy and mindfulness with the utilization of best practices, strategies, and measurements of success highlighted in the study.</p><p>
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Scott, Susan. "Demographic study of Penrith, Cumberland, 1557-1812, with particular reference to famine, plague and smallpox." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.260366.

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Chapman, David A. G. "The role of the immunoglobulin like periplasmic chaperone Caf1M in the export of the F1 capsular antigen of Yersinia pestis." Thesis, University of Reading, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312433.

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Walsh, Morrissey Jake. "The world "up so doun" : plague, society, and the discourse of order in the Canterbury tales." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=83845.

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Witnesses believed that the Black Death and subsequent fourteenth-century plagues threatened profound social change. However, Geoffrey Chaucer (c.1340-1400) does not appear to accord the plague a place of any importance in his works. This is especially surprising in the case of the Canterbury Tales , which presents a complex portrait of plague-era society. Chaucer's silence on the plague is reinforced by critical positions that deemphasize the effects of the plague and emphasize Chaucer's supposed lack of interest in his world. This thesis contends that the plague is in fact present in the Canterbury Tales in the guise of the changes that it threatened. By situating the Canterbury Tales in a network of literary and non-literary responses to the plague, I demonstrate that Chaucer participated in a discourse that attempted to restore order to a world that was seen to have been disordered---morally, socially, and physically---by the plague.
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Gascoine, Kelly Gayle. "Saving Children From the White Plague: The Marion County Tuberculosis Association's Crusade Against Tuberculosis, 1911-1936." Thesis, Connect to resource online, 2010. http://hdl.handle.net/1805/2188.

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Thesis (M.A.)--Indiana University, 2010.<br>Title from screen (viewed on June 4, 2010). Department of History, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): William H. Schneider, Robert G. Barrows, Stephen J. Jay. Includes vitae. Includes bibliographical references (leaves 107-112).
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Jillings, Karen. "'For the safte and preservation of the toune' : plague and the poor in early modern Aberdeen." Thesis, University of Aberdeen, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.394553.

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This thesis examines the incidence and effects of plague in early modern Aberdeen. In so doing, it refutes the presumption that Scotland lacks the sources necessary to allow the impact of past epidemics to be gauged and redresses the current imbalance in the historiography of plague studies. The unparalleled survival of Aberdeen's bureaucratic records allows detailed study of the city to be undertaken and enables the focus of responses to plague to shift from Italy to Northern Europe. Sixteenth-century Aberdeen was one of the nation's largest and most important burghs. Its supposed 'isolation' belied its diverse offerings, from which towns across the North Sea particularly benefited. The city as susceptible to plague yet suffered a comparatively low incidence of outbreaks. Free from plague for the entire fifteenth century, magistrates passed innovative regulations to combat the French Disease and subsequently dealt with two major plague epidemics, in the 1510s and 1540s. Aberdeen shared many of its myriad effects - social instability, disruption of government, and commercial disaster. Subsequent impoverishment overwhelmingly dictated the bureaucratic treatment of the poor; unlike elsewhere begging was not inherently considered a threat to social health, despite the acknowledgement that plague flourished amongst society's most deprived (and depraved) members. Poor relief became necessary only during outbreaks, when government had to implement temporary solutions in the absence of regulated charitable provision. Thereafter the city avoided outbreaks for a century. After the Reformation of 1560 plague was acknowledged as a divine punishment, whereas beforehand epidemics had been met with no apparent religious reaction. In three areas - the incidence of outbreaks, the bureaucratic treatment of the poor and the absence of a religious response - Aberdeen's experience of plague belies many traditional assumptions about early modern epidemics.
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TAYE, KISSI JIMMA. "VACCINE DEVELOPMENT AGAINST PLAGUE, GLANDERS AND MELIOIDOSIS IN THE FORMER SOVIET UNION IN COMPARSION TO THE CURRENT STATE OF GLOBAL KNOWLEDGE." Doctoral thesis, Universitätsbibliothek Leipzig, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-38336.

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The causative agents of plague (Y. pestis), glanders (B. mallei) and melioidosis (B. pseudomallei) are included in critical agents of bioterrorisim. They belong to the most intensively studied agents during cold war, specially in the former Soviet Union (FSU). Mostly what is known about these agents, particularly (Y. pestis ) is not available in English language publications. Many of the studies are written in Russian language and published in Russian scientific journals. Thus, the work is designed to evaluate, published and unpublished Russian language written data obtained, in comparisions to the current state of global knowledge on the pathogens in concern.
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Shakya, Arvind. "Mechanism of matrix metalloproteinase-14 (mmp-14) regulation during atherosclerosis." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/4436.

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Thesis (Ph. D.)--University of Missouri-Columbia, 2006.<br>"December 2006" The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Vita. Includes bibliographical references.
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Isherwood, Karen Elizabeth. "Quorum sensing in Yersinia pestis." Thesis, University of Nottingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.364667.

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42

Minardi, Diana. "Development of new genome-informed genotyping tools for Aphanomyces astaci." Thesis, University of Exeter, 2017. http://hdl.handle.net/10871/30137.

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Aphanomyces spp. are water moulds, eukaryotic fungus-like organisms, belonging to the class Oomycota. This genus contains primary pathogens of plants and animals as well as opportunistic and saprotrophic species. One of the animal parasites (A. astaci) is the causal agent of the crayfish plague, a disease listed by the World Organisation for Animal Health (OIE). It is believed that A. astaci was first introduced into Italy from the US in the late 19th century and rapidly spread in Europe causing the decline of native crayfish. It currently threatens to wipe out the UK native white-clawed crayfish (Austropotamobius pallipes). Random amplified polymorphic DNA (RAPD-PCR) on pure isolates of A. astaci distinguished five genotypes (A, B, C, D, and E). This distinction proved to be a useful tool for epidemiological studies aimed at understanding the history and spread of the disease in Europe; furthermore, there are differences in virulence among genotypes. No discriminatory morphological or physiological characters are available and widely used markers such as the internal transcribed spacer (ITS), the divergent domains regions (D1-D2) of nuclear large subunit (LSU) rDNA, and cytochrome c oxidase subunit I (COI) also fail to discriminate between A. astaci genotypes. There are some practical drawbacks to genotype by the currently available genotyping methods. Whole genome sequencing (WGS) was used to catalogue DNA single nucleotide variants and genotype-unique genomic regions that could be exploited as phylogenetic markers. These newly developed molecular markers were tested both on pure cultures and historical samples derived from outbreaks and carrier crayfish available in our laboratories, validating these genotyping methods, which represent new diagnostic tools aiding the detection and prevention of crayfish plague.
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Reddin, Karen Margaret. "Purification, immunogenicity and protective potency of the F1 antigen from Yersinia pestis." Thesis, Open University, 1998. http://oro.open.ac.uk/54548/.

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The area of self-esteem in people with learning disabilities has been largely neglected, and previous researchers have employed a variety of approaches. It is important to further our understanding in the context of providing appropriate clinical interventions and in monitoring the effect of social policy developments on the individuals at the receiving end of service provision. The study aimed to assess the reliability and validity of a set of measures devised specifically for use with learning disabled people, by Szivos-Bach (1993). The measures assess social comparisons, perception of stigma and aspirations and expectations. The study was carried out with 30 adults with mild and moderate learning disabilities between the ages of 18 and 65. The results provide initial support for the social comparisons test as a measure of self-esteem. Less evidence was found for the stigma questionnaire and the aspirations-expectations test. The results are discussed in the light of comparable research into self-esteem measures with non-learning disabled populations. Further research is required, and the most profitable way forward seems to be development of multi-dimensional measures of self-esteem.
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Vavlas, Belinda A. "Anti-Chinese Discrimination in Twentieth Century America: Perceptions of Chinese Americans During the Third Bubonic Plague Pandemic in San Francisco, 1900-1908." Youngstown State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1299600446.

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45

Fritts, Rachel(Rachel A. ). "Plague on the Prairie : the fight to save black-footed ferrets from the West's most insidious disease." Thesis, Massachusetts Institute of Technology, 2020. https://hdl.handle.net/1721.1/128984.

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Thesis: S.M. in Science Writing, Massachusetts Institute of Technology, Department of Comparative Media Studies/Writing, 2020<br>Cataloged from student-submitted PDF version of thesis.<br>Includes bibliographical references (pages 15-17).<br>When a single remaining population of black-footed ferrets was discovered in Meeteetse, Wyoming in 1981, scientists had one last chance to save North America's only native ferret from extinction. Though the discovered population numbered over 100 individuals when it was found, ferrets began to die at an alarming rate just a few years after the rediscovery of the species. With their options running out, the United States Fish and Wildlife Service made the drastic choice of pulling every single surviving ferret into captivity. Thanks to decades of captive breeding and release efforts involving hundreds of people, there are now a few hundred black-footed ferrets back in the wild today. The black-footed ferret recovery effort has yet to overcome its greatest challenge, however: plague. Keeping ferrets alive in the wild is time consuming and cost intensive. Every wild ferret needs to be rounded up and vaccinated, and insecticides are sprayed over hundreds of thousands of acres each year to stave off the looming threat of a plague outbreak. To make matters worse, ferrets are becoming more inbred each year, making them even more susceptible to disease. Recently the black-footed ferret recovery effort has turned to cutting-edge genetic technologies to introduce more diversity into the ferret line, and, eventually, resistance to the plague. Some researchers think that such drastic measures might now be the only way for black-footed ferrets to ever have a hope of surviving on their own in the wild again.<br>by Rachel Fritts.<br>S.M. in Science Writing<br>S.M.inScienceWriting Massachusetts Institute of Technology, Department of Comparative Media Studies/Writing
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46

Conlin, David Byrd. "Abundance of rodents on grasslands characterized by a patchy distribution of prairie dogs, urban development, and plague epidemics." Diss., Connect to online resource, 2005. http://wwwlib.umi.com/cr/colorado/fullcit?p1425773.

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47

Spyrou, Maria Alexandra [Verfasser]. "The evolutionary history of plague as revealed through the analysis of ancient Yersinia pestis genomes / Maria Alexandra Spyrou." Tübingen : Universitätsbibliothek Tübingen, 2020. http://d-nb.info/1218073055/34.

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48

Palace, Samantha G. "Plague and the Defeat of Mammalian Innate Immunity: Systematic Genetic Analysis of Yersinia pestis Virulence Factors: A Dissertation." eScholarship@UMMS, 2016. http://escholarship.umassmed.edu/gsbs_diss/836.

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Yersinia pestis, the causative agent of plague, specializes in causing dense bacteremia following intradermal deposition of a small number of bacteria by the bite of an infected flea. This robust invasiveness requires the ability to evade containment by the innate immune system. Of the various mechanisms employed by Y. pestis to subvert the innate immune response and to proliferate rapidly in mammalian tissue, only a few are well-characterized. Here, I present two complementary genetic analyses of Y. pestis adaptations to the mammalian environment. In the first, genome-wide fitness profiling for Y. pestis by Tn-seq demonstrates that the bacterium has adapted to overcome limitation of diverse nutrients during mammalian infection. In the second, a series of combinatorial targeted mutations disentangles apparent functional redundancy among the effectors of the Y. pestis type III secretion system, and we report that YpkA, YopT, and YopJ contribute to virulence in mice. We have also begun to investigate a novel relationship between Y. pestis and mammalian platelets, a highly abundant cell type in plasma. I present evidence that Y. pestis has evolved specific mechanisms to interfere with platelet activation, likely in order to evade immune responses and promote maintenance of bacteremia by undermining platelet thrombotic and innate immune functions. The principles guiding this work – systematic genetic analysis of complex systems, coupled with rational modification of in vitro assays to more closely mimic the in vivo environment – are a generalizable approach for increasing the efficiency of discovering new virulence determinants in bacterial pathogens.
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Hartman, Krysten Brooke. "The Shame of Preserving Honor: Why Honor Killings Still Plague the Hashemite Kingdom of Jordan in the 21st Century." Scholarship @ Claremont, 2010. http://scholarship.claremont.edu/cmc_theses/34.

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In Jordan, a woman is often murdered by members of her own family if she is found to have tainted the family's honor in any way. Refusing to enter into an arranged marriage, being seen alone with a male stranger or even wearing makeup have all been cited as incidents that shame the family and result in what are called "honor killings". These honor killings have continued to plague Jordan, and other countries in the Middle East, well into the 21st century, despite the country's progress towards modernization. The dominance of the patriarchal family and the inability of the country to experience economic growth are strong contributors to the perpetuation of these horrible crimes in a country that is considered to be relatively modern in this day and age.
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Brinkerhoff, Robert Joris. "Mammal and flea occurrence in association with black-tailed prairie dog (Cynomys ludovicianus) colonies: Implications for interspecific plague transmission." Connect to online resource, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3303859.

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