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1

Protocol for a plague: AIDS research, access to life-saving therapies & drug approval. Monument Press, 1994.

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2

Ron, Waksman, and Serruys P. W, eds. Handbook of the vulnerable plaque. Martin Dunitz, 2004.

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3

Valentin, Fuster, and Insull William, eds. Assessing and modifying the vulnerable atherosclerotic plaque. Futura Pub. Co., 2002.

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4

L, Kalkwarf Kenneth, Brunsvold Michael A, and Brooks Carol, eds. Plaque and calculus removal: Considerations for the professional. Quintessence Pub. Co., 1994.

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5

Renu, Virmani, ed. The vulnerable atherosclerotic plaque: Strategies for diagnosis and management. Blackwell Futura, 2007.

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6

Valentin, Fuster, ed. The vulnerable atherosclerotic plaque: Understanding, identification, and modification. Futura Pub. Co., 1999.

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7

Harrison, Sarah (Sarah J. C.). and College of Occupational Therapists, eds. Fatigue management for people with multiple sclerosis. 2nd ed. College of Occupational Therapists, 2007.

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8

La santé par les vitamines et les minéraux. Sélection Reader's Digest, 2003.

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9

MS - living symptom free: The true story of an MS patient. [publisher not identified], 2011.

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10

Dumesnil, Jean G. Bon poids, bon coeur avec la methode Montignac. Flammarion Quebec, 2002.

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11

Jürg, Kesselring, Siva Aksel, Thompson Alan J, and European Committee on Treatment and Research in Multiple Sclerosis. Congress., eds. Frontiers in multiple sclerosis. Martin Dunitz, 1999.

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12

The Hidden Plague: A Field Guide For Surviving and Overcoming Hidradenitis Suppurativa. Primal Nutrition, Inc, 2013.

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13

Grant, Tara. Hidden Plague: A Holistic Field Guide Managing Hidradenitis Suppurativa and Other Skin and Autoimmune Conditions. Bradventures LLC, 2019.

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14

Grant, Tara. The Hidden Plague: A Holistic Field Guide to Managing Hidradenitis Suppurativa & Other Skin and Autoimmune Conditions. Bradventures LLC, 2019.

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15

Fuster, Valentin, and William Insull. Assessing and Modifying the Vulnerable Atherosclerotic Plaque. Wiley & Sons, Incorporated, John, 2008.

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16

Narula, Jagat, Martin B. Leon, Renu Virmani, and James T. Willerson. Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management. Wiley & Sons, Incorporated, John, 2008.

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17

Narula, Jagat, Martin B. Leon, Renu Virmani, and James T. Willerson. Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management. Wiley & Sons, Incorporated, John, 2008.

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18

Verheugt, Freek W. A. Fibrinolytic therapy. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0038.

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Fibrinolytic agents are able to reopen blood vessels that are occluded by a fresh thrombus. Urokinase, streptokinase, and streptokinase derivatives were the first effective agents. Recombinant plasminogen activators became available and they are specific for thrombus-bound fibrin. Significant bleeding is the major side effect of fibrinolysis, a major hurdle for its use. The current era of mechanical reperfusion has made fibrinolytic therapy a niche treatment for acute arterial thrombosis such as ST elevation myocardial infarction and stroke. Only for pulmonary embolism with haemodynamic consequences and mechanical heart valve thrombosis may lytic therapy have a place in selected patients.
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19

Willerson, James T., Martin Leon, and Jagat Narula. The Vulnerable Atherosclerotic Plaque Strategies for Diagnosis and Management. Blackwell Publishing Limited, 2006.

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20

Edwards, Jane. Music Therapy. Edited by Jane Edwards. Oxford University Press, 2015. http://dx.doi.org/10.1093/oxfordhb/9780199639755.013.52.

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This chapter outlines the importance of understanding the dynamics of the service context along with the needs of the population being served in order to achieve effective implementation of music therapy programmes. The new music therapist, and the student, must take care to ensure they understand as much as possible about the population, the services, and the wider policy context in the place where they are providing services before translating research findings or the techniques described in case studies to their own developing practice. Music therapy has an emergent evidence base as provided through case reports, expert opinion, randomized controlled trials, and meta-analyses of existing studies. The evidence base points to the effectiveness of music therapy to address a range of needs, particularly in improving communication and social skills.
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21

Fuster, Valentin. The Vulnerable Atherosclerotic Plaque: Understanding, Identifi- cation and Modification. Blackwell Publishing Limited, 1999.

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22

Narula, Jagat, Martin B. Leon, Renu Virmani, and James T. Willerson. Vulnerable Atherosclerotic Plaque: Strategies for Diagnosis and Management. Wiley & Sons, Limited, John, 2007.

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23

(Contributor), Pierre Amarenco, Mark Brezinski (Contributor), Allen Burke (Contributor), and Valentin Fuster (Editor), eds. Assessing and Modifying the Vulnerable Atherosclerotic Plaque (American Heart Association Monograph Series). Blackwell Publishing Limited, 2002.

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24

Khachigian, Levon Michael. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. CRC, 2004.

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25

Saraiya, Ami, Deep Joshipura, and Alice Gottlieb. Psoriasis treatment. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198737582.003.0026.

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Psoriasis is an immune-mediated skin disease that is associated with various factors, including genetics, stress, infections, and environmental triggers. Numerous treatment options exist for plaque psoriasis including topical therapy, phototherapy, systemic therapy, and biological therapy. In order to select a treatment for a patient, a clinician must consider many aspects. First, one must assess the impact and burden of the disease on a patient as well as a patient’s expectations from therapy. Other important factors to consider include the severity of skin disease, location of psoriatic plaques, comorbidities and presence of psoriatic arthritis, efficacy of different treatments, potential side-effects, safety, and cost. In this chapter, an evidence-based review is presented on the treatment armamentarium for psoriasis as well as new biological treatments and those under investigation. In order to guide practitioners, several treatment algorithms are provided and others are referenced from the literature.
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26

Sutton, Caitlin D., and Olutoyin A. Olutoye. Anesthesia for Ex Utero Intrapartum Therapy. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0052.

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Fetuses with congenital head and neck anomalies which will result in impaired spontaneous respiration and difficulty in securing the airway after delivery may suffer asphyxia at birth. The ex utero intrapartum therapy (EXIT) offers such affected babies a chance at survival by allowing airway manipulations to occur after partial delivery of the baby, while the baby remains on utero-placental support. This very unique procedure requires extensive planning and multidisciplinary coordination with a multiplicity of specialties including maternal fetal medicine, pediatric surgery, pediatric otolaryngology, pediatric anesthesiology, neonatology, and pediatric cardiology. The preoperative planning takes place several days prior to the procedure and also involves meeting with the family. It is the intricacies of multidisciplinary team that require EXIT procedures to take place in certain highly specialized tertiary care fetal centers.
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27

Wong, Muh Geot, Bruce A. Cooper, and Carol A. Pollock. Preparation for renal replacement therapy. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0143_update_001.

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Although the primary aim of management in chronic kidney disease (CKD) is to prevent progression to stage 5 CKD, for many patients renal replacement therapy (RRT) is inevitable. Planning for the initiation of dialysis is aimed at ensuring that it takes place in a supported environment in which adverse events will be minimized, that the modality chosen is appropriate for the individual circumstances, and the patient has full knowledge of what RRT entails. Beginning dialysis inevitably involves medical, psychological, family, and social issues, and preparation for RRT is optimally managed by a team with appropriate expertise in these areas. Multidisciplinary education programmes that inform patients and their families about their disease and the treatment options are likely to result in patients starting dialysis in a planned and elective manner.
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28

Opie, Lionel. Optimal Medical Therapy Post-AMI. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199544769.003.0006.

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• The management of an acute myocardial infarction can be divided into four phases: (a) The initial acute ischaemia causes severe prolonged chest pain when the patient is rushed to a Coronary or Intensive Care Unit; (b) Within the next few hours as ischaemia changes into infarction, the aim at this step is to restore blood flow in the occluded artery by thrombolysis or by percutaneous coronary intervention (PCI); (c) Next, the infarct is established and the left ventricle undergoes early remodeling; (d) Finally, follows the post-AMI post-hospital phase when continued left ventricular remodeling takes place• The therapeutic management of each of these steps can be optimized using appropriate medical therapy including antiplatelet and antithrombotic therapy, beta-blockers, ACE-inhibitors and angiotensin receptor blockers, lipid-lowering drugs, aldosterone antagonists, omega-3 fatty acids and so on.
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29

Horton, Patrick, Deborah J. Peet, David G. Sutton, and Colin J. Martin. Radiotherapy: brachytherapy and unsealed radionuclide therapy. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199655212.003.0020.

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The facilities and safe procedures required for afterloading (remote low, pulsed, and high dose-rate and manual), permanent seed implants, external plaques, intraoperative radiotherapy with X-ray sources, and unsealed radionuclide therapy (inpatient and outpatient) are described. Treatment room design makes particular reference to the shielded rooms required for high dose-rate afterloading and unsealed radionuclide therapy with I-131 and examples are included for calculating shielding thickness to achieve required dose constraints. Room location, layout, good practice, and engineering controls are also described, together with radiation surveys of completed facilities. The storage, handling, and record-keeping for both sealed and unsealed sources is discussed. The need for risk assessments and contingency plans is emphasized. Data for calculating shielding thickness and X-ray scatter for maze design are provided.
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30

Harrison, Amy. Cognitive Remediation Therapy for Eating Disorders. Edited by W. Stewart Agras and Athena Robinson. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780190620998.013.21.

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Eating disorders (EDs) have been described as among the most difficult psychiatric disorders to treat. Intervening early appears to be associated with better prognosis, although a subgroup of 20% of individuals may develop a more severe and enduring form of illness, which is associated with higher rates of mortality. Many patients with EDs who come into contact with clinical services may have extreme ambivalence toward change, which is often observed through high treatment dropout rates and difficulties engaging in treatment. This chapter outlines cognitive remediation therapy (CRT) for eating disorders, a treatment enhancer designed to support individuals with severe and complex forms of illness. This chapter explores how CRT has been used, examines its efficacy, reflects on its place as part of an overall treatment package for patients with EDs, and finally, explores options for future research in the field.
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31

Michael, Khachigian Levon, ed. High-risk atherosclerotic plaques: Mechanisms, imaging, models, and therapy. CRC Press, 2005.

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32

Khachigian, Levon Michael. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. Taylor & Francis Group, 2004.

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33

Khachigian, Levon Michael. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. Taylor & Francis Group, 2004.

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34

Khachigian, Levon Michael. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. Taylor & Francis Group, 2010.

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35

Khachigian, Levon Michael. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. Taylor & Francis Group, 2004.

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36

Khachigian, Levon Michael. High-Risk Atherosclerotic Plaques: Mechanisms, Imaging, Models, and Therapy. Taylor & Francis Group, 2004.

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37

Ali, Ased, and Rob Pickard. Complicated urinary tract infection. Edited by Neil Sheerin. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0178.

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‘Complicated’ urinary tract infection (UTI) indicates infection occurring in anatomically or functionally abnormal urinary tract. Infections are not only more likely in such circumstances, but they are more likely to lead to complications such as acute pyelonephritis, and are frequently more difficult to eradicate, requiring more prolonged antimicrobial therapy. Some causes may be associated with susceptibility to specific micro-organisms. There may occasionally be a limited place for prophylactic therapy.
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38

Ramrakha, Punit, and Jonathan Hill, eds. Coronary artery disease. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199643219.003.0005.

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Atherosclerosis: pathophysiology 212Development of atherosclerotic plaques 214Epidemiology 216Assessment of atherosclerotic risk 218Risk factors for coronary artery disease 220Hypertension 226Treatment of high blood pressure 228Combining antihypertensive drugs 230Lipid management in atherosclerosis 232Lipid-lowering therapy 236When to treat lipids ...
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39

Kidd, Edwina, and Ole Fejerskov. Essentials of Dental Caries. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780198738268.001.0001.

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Dental caries (tooth decay) is one of the most highly prevalent disease around the world affecting a significant proportion of the population. Dental caries may take place on any tooth surface in the oral cavity where dental plaque is allowed to develop over a period of time. Understanding its causes and progression allows the dental team to prevent and manage it so that patients can maintain healthy teeth for life. The fourth edition of Essentials of Dental Caries provides readers with an up-to-date, clinically relevant guide to dental caries. Written in an accessible style, the authors explain the biological and socioeconomic background of lesion development and progress. Current methods of clinical diagnosis and evidence based management are outlined in clearly laid out and highly illustrated chapters. This book is essential reading for students and practitioners of dentistry, dental therapy, dental hygiene, and oral health educators.
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40

Bueno, Héctor, and José A. Barrabés. Non-ST-segment elevation acute coronary syndromes. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0046.

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Non-ST-segment elevation acute coronary syndromes are life-threatening disorders, usually caused by acute coronary thrombosis and subsequent myocardial ischaemia, presenting without persistent ST-segment elevation in the initial electrocardiogram. According to the occurrence of myocardial necrosis, non-ST-segment elevation acute coronary syndromes are divided into non-ST-segment myocardial infarction or unstable angina. The management of non-ST-segment elevation acute coronary syndromes requires an early diagnosis and risk stratification, urgent hospitalization, monitoring, and medical treatment, including antithrombotic therapy with dual antiplatelet therapy (aspirin plus one P2Y12 inhibitor) and parenteral anticoagulation, anti-ischaemic treatment, and preventative therapies. After the initial medical therapy is established, an invasive strategy, consisting of coronary angiography with coronary revascularization (either percutaneous coronary intervention or coronary bypass graft surgery), as appropriate, should be decided. The timing of the invasive strategy should be adjusted, according to the patient’s risk. Given the high event rate of patients with non-ST-segment elevation acute coronary syndromes after hospital discharge, an aggressive long-term preventative therapy should be put in place to improve prognosis.
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41

Bueno, Héctor, and José A. Barrabés. Non-ST-segment elevation acute coronary syndromes. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0046_update_001.

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Non-ST-segment elevation acute coronary syndromes are life-threatening disorders, usually caused by acute coronary thrombosis and subsequent myocardial ischaemia, presenting without persistent ST-segment elevation in the initial electrocardiogram. According to the occurrence of myocardial necrosis, non-ST-segment elevation acute coronary syndromes are divided into non-ST-segment myocardial infarction or unstable angina. The management of non-ST-segment elevation acute coronary syndromes requires an early diagnosis and risk stratification, urgent hospitalization, monitoring, and medical treatment, including antithrombotic therapy with dual antiplatelet therapy (aspirin plus one P2Y12 inhibitor) and parenteral anticoagulation, anti-ischaemic treatment, and preventative therapies. After the initial medical therapy is established, an invasive strategy, consisting of coronary angiography with coronary revascularization (either percutaneous coronary intervention or coronary bypass graft surgery), as appropriate, should be decided. The timing of the invasive strategy should be adjusted, according to the patient’s risk. Given the high event rate of patients with non-ST-segment elevation acute coronary syndromes after hospital discharge, an aggressive long-term preventative therapy should be put in place to improve prognosis.
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42

Bueno, Héctor, and José A. Barrabés. Non-ST-segment elevation acute coronary syndromes. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0046_update_002.

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Non-ST-segment elevation acute coronary syndromes are life-threatening disorders, usually caused by acute coronary thrombosis and subsequent myocardial ischaemia, presenting without persistent ST-segment elevation in the initial electrocardiogram. According to the occurrence of myocardial necrosis, non-ST-segment elevation acute coronary syndromes are divided into non-ST-segment myocardial infarction or unstable angina. The management of non-ST-segment elevation acute coronary syndromes requires an early diagnosis and risk stratification, urgent hospitalization, monitoring, and medical treatment, including antithrombotic therapy with dual antiplatelet therapy (aspirin plus one P2Y12 inhibitor) and parenteral anticoagulation, anti-ischaemic treatment, and preventative therapies. After the initial medical therapy is established, an invasive strategy, consisting of coronary angiography with coronary revascularization (either percutaneous coronary intervention or coronary bypass graft surgery), as appropriate, should be decided. The timing of the invasive strategy should be adjusted, according to the patient’s risk. Given the high event rate of patients with non-ST-segment elevation acute coronary syndromes after hospital discharge, an aggressive long-term preventative therapy should be put in place to improve prognosis.
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43

Multiple Sclerosis: Etiology, Diagnosis, and New Treatment Strategies. Humana, 2010.

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44

Waje-Andreassen, Ulrike, and Nicola Logallo. Vascular imaging: Ultrasound. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198722366.003.0009.

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After computed tomography and computed tomography angiography or magnetic resonance imaging and magnetic resonance angiography at admission, ultrasound is the most important diagnostic tool to confirm angiographic findings and to closely follow-up patients until the clinical situation has stabilized. Thrombolysis and interventional therapy have given transcranial ultrasound a very important role in bedside monitoring of occlusions, collaterals, cerebral haemodynamics, and vasoreactivity. Detection of flow changes in sickle cell disease, circulating emboli, and right-to-left shunts may guide treatment decisions. Sonothrombolysis and targeted drug delivery are today’s research projects for acute treatment by ultrasound. Extracranial cerebrovascular ultrasound is an ‘all-round’ diagnostic tool modifying angiographic results, showing minor arterial wall disease, plaques, and plaque instability. Microembolic signals during scanning may contribute to finding the cause of stroke. In stroke prevention, ultrasound delivers the possibility for staging of arteries and improving targeted intervention. Ultrasound images may also serve as educational tools for patients to underline the need for continuous medical treatment and lifestyle changes, and may improve compliance.
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45

Teasdale, John D. The relationship between cognition and emotion: the mind-in-place in mood disorders. Oxford University Press, 2015. http://dx.doi.org/10.1093/med:psych/9780192627254.003.0004.

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Chapter 4 explores the relationship between cognition and emotion using the metaphor of ‘mind-in-place’. It considers three basic ideas – that we do not have one mind, but many, which vary in dominance; that mood disorders can be thought of in terms of the persistence of particular minds-in-place; and that cognitive behaviour therapies for mood disorders work by helping clients shift out of the mind-in-place in which they are stuck. The chapter also discusses the psychological treatment of depression, and cognitive therapy.
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46

van Lier, Felix, and Robert Jan Stolker. Preoperative assessment and optimization. Edited by Jonathan G. Hardman. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0040.

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Perioperative cardiovascular complications (including myocardial ischaemia and myocardial infarction) are the predominant cause of morbidity and mortality in patients undergoing non-cardiac surgery. The pathophysiology of perioperative myocardial infarction is complex. Prolonged myocardial ischaemia due to the stress of surgery in the presence of a haemodynamically significant coronary lesion, leading to subendocardial ischaemia, and acute coronary artery occlusion after plaque rupture and thrombus formation contribute equally to these devastating events. Perioperative management aims at optimizing the patient’s condition by identification and modification of underlying cardiac risk factors and diseases. The first part of this chapter covers current knowledge on preoperative risk assessment. Current risk indices, the value of additional testing, and new preoperative cardiac risk makers are investigated. During recent decades there has been a shift from the assessment and treatment of the underlying culprit coronary lesion towards a systemic medical therapy aiming at prevention of myocardial oxygen supply–demand mismatch and coronary plaque stabilization. In the second part of this chapter, risk-reduction strategies are discussed, including β‎-blocker therapy, statins, and aspirins. A central theme in this chapter will focus on long-term cardiovascular risk reduction. Patients who undergo non-cardiac (vascular) surgery are particularly prone to long-term adverse cardiac outcomes. The goal of perioperative cardiovascular risk identification and modification should not be limited to the perioperative period, but should extend well into the postoperative period.
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47

Jardine, Alan G., and Rajan K. Patel. Lipid disorders of patients with chronic kidney disease. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0102.

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The risk of developing cardiovascular (CV) disease is increased in patients with chronic kidney disease (CKD) and although dyslipidaemia is a major contributory factor to the development of premature CV disease, the relationship is complex. Changes in lipid fractions are related to glomerular filtration rate and the presence and severity of proteinuria, diabetes, and other confounding factors. The spectrum of CV disease changes from lipid-dependent, atheromatous coronary disease in early CKD to lipid-independent, non-coronary disease, manifesting as heart failure, and sudden cardiac death in advanced and end-stage renal disease. Statin-based lipid-lowering therapy is proven to reduce coronary events across the spectrum of CKD. The relative reduction in overall CV events, however, diminishes as CKD progresses and the proportion of lipid-dependent coronary events declines. There is nevertheless a strong argument for the use of statin-based therapy across the spectrum of CKD. The argument is particularly strong for those patients with progressive renal disease who will eventually require transplantation, in whom preventive therapy should start as early as possible. The SHARP study established the benefits and endorses the use of lipid-lowering therapy in CKD 3-4 but uncertainty about the value of initiation of statin therapy in CKD 5 remains. There is, however, no rationale for stopping agents started earlier in the course of the illness for compelling indications, particularly in those who will ultimately be transplanted. The place of high-density lipoprotein-cholesterol raising and triglyceride lowering therapy needs to be assessed in trials. Modifying dyslipidaemia in CKD has demonstrated that lipid-dependent atheromatous cardiovascular disease is only one component of the burden of CV disease in CKD patients, that this is proportionately less in advanced CKD, and that modification of lipid profiles is only one part of CV risk management.
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48

30-Day Heart Tune-Up: A Breakthrough Medical Plan to Prevent and Reverse Heart Disease. Little, Brown Book Group Limited, 2015.

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49

Masley, Steven, and Douglas D. Schocken. 30-Day Heart Tune-Up: A Breakthrough Medical Plan to Prevent and Reverse Heart Disease. Center Street, 2014.

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50

The 30Day Heart TuneUp. Little, Brown & Company, 2014.

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