Academic literature on the topic 'Planar cell polarity pathway'

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Journal articles on the topic "Planar cell polarity pathway"

1

Harrison, Carl, Hongyu Shao, Helen Strutt, and David Strutt. "Molecular mechanisms mediating asymmetric subcellular localisation of the core planar polarity pathway proteins." Biochemical Society Transactions 48, no. 4 (2020): 1297–308. http://dx.doi.org/10.1042/bst20190404.

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Planar polarity refers to cellular polarity in an orthogonal plane to apicobasal polarity, and is seen across scales from molecular distributions of proteins to tissue patterning. In many contexts it is regulated by the evolutionarily conserved ‘core' planar polarity pathway that is essential for normal organismal development. Core planar polarity pathway components form asymmetric intercellular complexes that communicate polarity between neighbouring cells and direct polarised cell behaviours and the formation of polarised structures. The core planar polarity pathway consists of six structura
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2

Kacker, Sandeep, Varuneshwar Parsad, Naveen Singh, et al. "Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation." Journal of Developmental Biology 12, no. 2 (2024): 12. http://dx.doi.org/10.3390/jdb12020012.

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The planar cell polarity (PCP) system is essential for positioning cells in 3D networks to establish the proper morphogenesis, structure, and function of organs during embryonic development. The PCP system uses inter- and intracellular feedback interactions between components of the core PCP, characterized by coordinated planar polarization and asymmetric distribution of cell populations inside the cells. PCP signaling connects the anterior–posterior to left–right embryonic plane polarity through the polarization of cilia in the Kupffer’s vesicle/node in vertebrates. Experimental investigation
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3

Wansleeben, Carolien, and Frits Meijlink. "The planar cell polarity pathway in vertebrate development." Developmental Dynamics 240, no. 3 (2011): 616–26. http://dx.doi.org/10.1002/dvdy.22564.

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4

Wu, Gang, Jiao Ge, Xupei Huang, Yimin Hua, and Dezhi Mu. "Planar Cell Polarity Signaling Pathway in Congenital Heart Diseases." Journal of Biomedicine and Biotechnology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/589414.

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Congenital heart disease (CHD) is a common cardiac disorder in humans. Despite many advances in the understanding of CHD and the identification of many associated genes, the fundamental etiology for the majority of cases remains unclear. The planar cell polarity (PCP) signaling pathway, responsible for tissue polarity inDrosophilaand gastrulation movements and cardiogenesis in vertebrates, has been shown to play multiple roles during cardiac differentiation and development. The disrupted function of PCP signaling is connected to some CHDs. Here, we summarize our current understanding of how PC
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5

Werner, Michael E., Peter Hwang, Fawn Huisman, Peter Taborek, Clare C. Yu, and Brian J. Mitchell. "Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells." Journal of Cell Biology 195, no. 1 (2011): 19–26. http://dx.doi.org/10.1083/jcb.201106110.

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Planar cell polarization represents the ability of cells to orient within the plane of a tissue orthogonal to the apical basal axis. The proper polarized function of multiciliated cells requires the coordination of cilia spacing and cilia polarity as well as the timing of cilia beating during metachronal synchrony. The planar cell polarity pathway and hydrodynamic forces have been shown to instruct cilia polarity. In this paper, we show how intracellular effectors interpret polarity to organize cellular morphology in accordance with asymmetric cellular function. We observe that both cellular a
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Funato, Yosuke, Tatsuo Michiue, Takeshi Terabayashi, et al. "Nucleoredoxin regulates the Wnt/planar cell polarity pathway inXenopus." Genes to Cells 13, no. 9 (2008): 965–75. http://dx.doi.org/10.1111/j.1365-2443.2008.01220.x.

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7

LaMonica, Kristi A., Maya Bass, and Laura Grabel. "The planar cell polarity pathway regulates parietal endoderm outgrowth." Developmental Biology 306, no. 1 (2007): 371. http://dx.doi.org/10.1016/j.ydbio.2007.03.542.

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8

LaMonica, Kristi, Maya Bass, and Laura Grabel. "The planar cell polarity pathway directs parietal endoderm migration." Developmental Biology 330, no. 1 (2009): 44–53. http://dx.doi.org/10.1016/j.ydbio.2009.03.008.

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9

Peunova, Natalia, and Grigori Enikolopov. "P61. NO links planar cell polarity pathway with ciliogenesis." Nitric Oxide 19 (2008): 57. http://dx.doi.org/10.1016/j.niox.2008.06.158.

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10

Rocque, Brittany, and Elena Torban. "Planar Cell Polarity Pathway in Kidney Development and Function." Advances in Nephrology 2015 (February 25, 2015): 1–15. http://dx.doi.org/10.1155/2015/764682.

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The evolutionarily conserved planar cell polarity (PCP) signaling pathway controls tissue polarity within the plane orthogonal to the apical-basal axis. PCP was originally discovered in Drosophila melanogaster where it is required for the establishment of a uniform pattern of cell structures and appendages. In vertebrates, including mammals, the PCP pathway has been adapted to control various morphogenetic processes that are critical for tissue and organ development. These include convergent extension (crucial for neural tube closure and cochlear duct development) and oriented cell division (n
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