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Dissertations / Theses on the topic 'Plant cell cycle'

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1

Jopson, Martin Frederick. "Plant microtubules, their associated proteins and the cell cycle." Thesis, University of East Anglia, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318090.

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2

Kulaveerasingam, Harikrishna. "A molecular study of dedifferentiation and cell cycle reactivation in mechanically isolated asparagus cells." Thesis, University of Leicester, 1989. http://hdl.handle.net/2381/33631.

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Mechanically isolated cell cultures were chosen as a model system to examine wound-induced dedifferentiation at the molecular level as large quantities of physiologically and morphologically similar G1-arrested mesophyll cells could be obtained. Within 5 days of culture such non-dividing, photosynthetic cells become heterotrophic, and have completed a first nuclear division and cytokinesis. There are few changes in cell morphology during the first 2-3 days in culture. However, during this period there is a massive increase in respiration rate and total RNA synthesis. Following DNA synthesis th
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3

Harper, John D. I. "Genetical and ultrastructural analysis of the Chlamydomonas cell cycle." Thesis, Queen's University Belfast, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236312.

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4

Rafiei, Golnaz. "Studies on the role of WEE1 in the plant cell cycle." Thesis, Cardiff University, 2012. http://orca.cf.ac.uk/30683/.

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WEE 1 is a key eukaryotic cell cycle regulator. In plants it has a clear role at the DNA damage/ DNA replication checkpoints. I aimed to discover the functional significance of interactions between WEE1 and other cellular proteins in Arabidopsis thaliana and Nicotiana tabacum. First I examined effects of ectopic expression of Arabidopsis WEE1 (Arath;WEE1) in transgenic tobacco and tobacco WEE1 (Nicta;WEE1) in transgenic Arabidopsis. Western blotting using a plant WEE1 antibody showed that expression of Nicta;WEE1 in Arabidopsis caused increases in total WEE1 protein. The response of primary ro
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5

Spadafora, N. D. "Effect of CDC25 and WEE1 on plant cell cycle and morphogenesis." Thesis, University of Worcester, 2010. http://eprints.worc.ac.uk/745/.

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The cell cycle comprises the four phases of, G1, S-phase, G2 and mitosis. Two critical transitions are G1/S and G2/M; the latter is regulated by WEE1 kinase and CDC25 phosphatases. The scope of this thesis was to investigate the regulation of the G2/M transition of the cell cycle by WEE1 and CDC25, and how these genes interface with plant growth regulators in Arabidopsis thaliana. In Arabidopsis roots, the frequency of lateral roots was found to be increased by ectopic expression of Schizosaccharomyces pombe (Sp)cdc25e and reduced by Arath;WEE1 expression. I examined the effect of Arath;WEE1 a
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6

Webb, Penelope 1967. "Effects of yeast cell cycle gene expression in transgenic Nicotiana tabacum." Monash University, Dept. of Biological Sciences, 2001. http://arrow.monash.edu.au/hdl/1959.1/9084.

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7

He, Enuo. "Stochastic modelling of the cell cycle." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:04185cde-85af-4e24-8d06-94b865771cf1.

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Precise regulation of cell cycle events by the Cdk-control network is essential for cell proliferation and the perpetuation of life. The unidirectionality of cell cycle progression is governed by several critical irreversible transitions: the G1-to-S transition, the G2-to-M transition, and the M-to-G1 transition. Recent experimental and theoretical evidence has pulled into question the consensus view that irreversible protein degradation causes the irreversibility of those transitions. A new view has started to emerge, which explains the irreversibility of cell cycle transitions as a consequen
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8

Vieira, Paulo. "Cell cycle maneuvering : a strategy taken by plant parasitic nematodes to induce specialized feeding sites in plant roots." Nice, 2012. http://www.theses.fr/2012NICE4114.

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9

Fülöp, Katalin. "Analysis of two plant protein complexes associated with transcription and cell cycle progression." Szegedi Tudományegyetem, 2005. http://www.theses.fr/2005PA112194.

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10

Su, Yingtao. "Function and regulation of myc-family bHLHZip transcription factors during the animal and plant cell cycle /." Uppsala : Dept. of Plant Biology and Forest Genetics, Swedish University of Agricultural Sciences, 2008. http://epsilon.slu.se/200836.pdf.

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11

Douglas, Mary Elizabeth. "Cost analysis and balance-of-plant of a solid oxide fuel cell/gas turbine combined cycle." Thesis, Georgia Institute of Technology, 2003. http://hdl.handle.net/1853/17960.

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12

Siciliano, Ilario. "Effect of plant WEE1 on the cell cycle and development in Arabidopsis thaliana and Nicotiana tabacum." Thesis, Cardiff University, 2006. http://orca.cf.ac.uk/56100/.

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In eukaryotes the regulatory cell cycle gene, WEE1, encodes a protein kinase. In late G2, it inactivates cyclin-dependent kinase (CDKs) in the CDK-cyclinA/B complexes, by phosphorylating the CDK on tyrosine 15. This can result in a delay in mitosis. Expression of Arabidopsis thaliana homologue of WEE1 (AtWEEl) in fission yeast resulted in an elongated cell length phenotype in the same way as over expression of fission yeast weel. I have tested whether At WEE1 could also induce this effect in tobacco cells and Arabidopsis plant roots. The tobacco BY-2 cells have been transformed with AtWEEl, bo
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13

Novak, Zsofia A. "The role and regulation of Asterless in the centrosome cycle." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:4fadaef1-8c9e-4c70-ac59-47f35af3988e.

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Centrosomes are the main microtubule organizing centres in animal cells and are formed by a pair of centrioles together with surrounding pericentriolar material (PCM). Cycling cells duplicate their centrosomes strictly once per cell cycle. This process is driven by the semi-conservative duplication of the centrioles that are found at the centrosome core. During the exit from mitosis the two centrioles within the single inherited centrosome separate, and upon the start of S-phase each of these inherited mother centrioles assembles an adjacent daughter at its side. This process results in two co
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14

Farrar, Kerrie. "Exordium : a novel gene in Arabidopsis identified by promoter trapping." Thesis, Durham University, 2000. http://etheses.dur.ac.uk/4361/.

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The aim of the project was to characterize the expression of a GUS promoter trap in a transgenic line of Arabidopsis thaliana, and to investigate the function of the tagged gene. GUS expression in the transgenic line, designated line EM2, was found to be localized to embryos, and to the regions of most active cell division in the seedling, notably the apical meristems and young leaves. The tagged gene was named EXORDIUM (EXO). Line EM2, which contains a single copy of the promoter trap T-DNA, was found to have no obvious phenotype when homozygous for the T-DNA insertion, and when grown under a
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15

Tan, Yi-Hsun. "Investigation of G1 Arrest Mechanisms Induced by Sanguisorba officinalis Extracts in B16F10 Cells." Kyoto University, 2019. http://hdl.handle.net/2433/245331.

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16

Taylor, Marcus Andrew. "The effects of light on the cell cycle in the shoot apex of Silene coeli-rosa (L.) Godron during floral evocation." Thesis, Cardiff University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304803.

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17

Skirycz, Aleksandra. "Functional analysis of selected DOF transcription factors in the model plant Arabidopsis thaliana." Phd thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2008/1698/.

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Transcription factors (TFs) are global regulators of gene expression playing essential roles in almost all biological processes, and are therefore of great scientific and biotechnological interest. This project focused on functional characterisation of three DNA-binding-with-one-zinc-finger (DOF) TFs from the genetic model plant Arabidopsis thaliana, namely OBP1, OBP2 and AtDOF4;2. These genes were selected due to severe growth phenotypes conferred upon their constitutive over-expression. To identify biological processes regulated by OBP1, OBP2 and AtDOF4;2 in detail molecular and physiologi
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18

Kryvych, Sergiy. "Gene expression profiling in different stages of development of Arabidopsis thaliana leaftrichomes at the single cell level." Phd thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2008/1747/.

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Each organ of a multicellular organism is unique at the level of its tissues and cells. Furthermore, responses to environmental stimuli or developmental signals occur differentially at the single cell or tissue level. This underlines the necessity of precise investigation of the “building block of life” -the individual cell. Although recently large amount of data concerning different aspects of single cell performance was accumulated, our knowledge about development and differentiation of individual cell within specialized tissue are still far from being complete. To get more insight into p
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19

Kesoglidou, Poli Xenia. "E2F7 : a member of the E2F family with a novel mechanism of transcriptional repression." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:5694f75b-0e73-493c-a6bd-da10793aded3.

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The mammalian E2F family of transcription factors plays a crucial role in the regulation of cellular proliferation, apoptosis and differentiation. E2F7 and E2F8 are the most recently identified family members and have unusual features that distinguish them from other members in the E2F family, including two distinct DNA-binding domains that bind to DNA in a DP-independent manner. E2F7 and E2F8 have been shown to be transcriptional repressors. However, the mechanism by which E2F7 represses E2F responsive gene expression remains to be elucidated. The results presented here provide the first insi
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20

Cabral, do Nascimento Danila. "La biogenèse des galles induites par des phyto-nématodes dépend de l'hyperactivation du cycle cellulaire : études fonctionnelles des nouveaux acteurs du cycle mitotique et de l'endocycle dans les cellules géantes." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2019. http://theses.univ-cotedazur.fr/2019AZUR6001.

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Lors des vingt dernières années, l’utilisation d’Arabidopsis thaliana en tant que plante modèle a permis d’accélérer les découvertes biologiques dans l’étude de nombreuses interactions plante-pathogènes tant au niveau moléculaire que cellulaire. Arabidopsis réagis de manière similaire aux plantes cultivées face aux attaques de nombreux pathogènes, y compris les nématodes. Meloidogyne incognita est un nématode endoparasite de la racine des plantes causant de lourdes pertes agronomiques estimées à plusieurs milliards de dollars par an. Afin d’induire la formation de sites nourriciers dans la rac
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21

Savarin, Julie. "Caractérisation de la voie TCTP (TRANSLATIONALLY CONTROLLED TUMOR PROTEIN) chez Arabidopsis thaliana : identification des régulateurs de son accumulation et importance de la voie au cours du développement embryonnaire." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEN001.

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TCTP (Translationally Controlled Tumor Protein) est une protéine très conservée chez l'ensemble des eucaryotes. C’est une protéine vitale impliquée dans divers processus essentiels, et pour de nombreux organismes son absence conduit à la létalité dès les stades embryonnaires.Chez les animaux comme chez les végétaux, TCTP joue un rôle primordial dans la croissance et le développement des individus. En plus de son implication dans l’apoptose et la réparation de l’ADN, TCTP favorise la prolifération cellulaire, et se trouve donc être un élément important de la tumorigenèse. Chez les végétaux, la
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22

Hall-Ponselè, Andrew M. "Genetic engineering of the primary/secondary metabolic interface in tobacco BY-2 cells." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:be5a3ee3-33c7-455c-b043-409987395f98.

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The supply of precursors from primary metabolism is often overlooked when engineering secondary metabolism for increased product yields. This is because precursor supply may be assumed to be non-limiting, and it is considered difficult to engineer primary metabolism, because control of carbon flow (flux) is generally distributed among most enzymes of the pathway. The aim of this thesis was to increase the production of sterols, part of the isoprenoid class of secondary metabolites, in tobacco (Nicotiana tabacum) Bright Yellow 2 (BY-2) cell cultures. This was achieved by genetically engineering
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23

Lee, Weon-Keun. "Screening for homologues of fission yeast cell cycle genes in plants." Thesis, University of Cambridge, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621893.

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24

Trolet, Adrien. "Cell cycle-dependent regulation and function of ARGONAUTE 1 in plants." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ110.

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Chez tous les eucaryotes, la régulation de l’expression génique est primordiale pour le contrôle du cycle cellulaire. Un large éventail de gènes, incluant des régulateurs essentiels du cycle, mais aussi d’autre gènes impliqués dans la transduction du signal, la régulation hormonale et le métabolisme sont ainsi exprimé à certaines phases du cycle. Ces changements sont contrôlés à de multiples niveaux, notamment de façon transcriptionnelle et post-traductionnelle. Chez les mammifères, il est aujourd’hui évident que les micro ARNs contribuent à cette régulation en ciblant spécifiquement les trans
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25

Lewis, Spenser M. "Simplified core physics and fuel cycle cost model for preliminary evaluation of LSCR fueling options." Thesis, Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/51772.

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The Liquid Salt Cooled Reactor (LSCR) provides several potential benefits compared to pressurized water-cooled reactor systems. These include low operating pressure of the liquid salt coolant, the high burnup tolerance of the fuel, and the high operating temperatures which leads to increases in efficiency. However, due to inherently low heavy metal loading, the fuel cycle design presents specific challenges. In order to study options for optimizing the fuel design and fuel cycle, SCALE6.1 was used to create simplified models of the reactor and look at various parameters. The primary parameters
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26

Silva, Tereza Cristina da. "Efeitos anti-neoplásicos da raiz de Pfaffia paniculata (Ginseng brasileiro) no modelo de hepatocarcinogênese murina e em cultura de células de hepatocarcinoma humano." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/10/10133/tde-02062008-095506/.

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A raiz pulverizada de Pfaffia paniculata e seu extrato butanólico apresentam propriedades antineoplásicas, quimiopreventivas e antiangiogênicas, onde muitos indícios conferem às saponinas triterpenóides presentes nestas raízes as propriedades antitumorais observadas. Sabe-se que saponinas de diversos tipos de plantas possuem capacidade de interferir diretamente no ciclo celular de células tumorais. Assim, considerando os efeitos inibitórios das raízes e extratos de P. paniculata sobre a proliferação celular, o objetivo deste trabalho foi compreender os mecanismos envolvidos na ação quimiopreve
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27

Lebogo, Kgomotso Welheminah. "The evaluation of the effects of semi-purified extracts of Commelina benghalensis on the molecular events associated with the growth, apoptosis and cell cycle progression of Jurkat-T cells." Thesis, University of Limpopo (Turfloop Campus), 2007. http://hdl.handle.net/10386/914.

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28

Mbazima, Vusi G. "The Effects of Crude Methanolic Extract of Commelina benghalensis Linn on the Expression of Apoptotic and Cell Division Cycle Genes in Jurkat T and Wil-2 NSCancer Cell Lines." Thesis, University of Limpopo (Turfloop Campus), 2009. http://hdl.handle.net/10386/937.

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Thesis (Ph.D. (Biochemistry)) --University of Limpopo, 2009<br>Commelina benghalensis Linn is used in traditional medicine in several Asian and African countries for the treatment of various ailments such as stomach irritations, burns, sore throat and feet, diarrhoea and as an anti-inflammatory agent. Recently, our laboratory showed that the crude methanolic extract of Commelina benghalensis L (CMECB) exhibits growth inhibitory and proapoptotic effects in Jurkat T and Wil-2 NS cancer cell lines. In this study, the precise molecular mechanism(s) associated with CMECB-induced growth inhib
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29

Nafati, Mehdi. "Caractérisation fonctionnelle des inhibiteurs de Cyclin-Dependent Kinase (CDK) dans le fruit de tomate (Solanum lycopersicum)." Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21712/document.

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Au sein de l’unité mixte de recherche 619 de l’Institut National de Recherche Agronomique, le groupe « Organogénèse du Fruit et Endoréduplication » étudie les acteurs moléculaires prenant part au contrôle du cycle cellulaire dans le fruit de tomate. L’objet de la présente thèse est l’étude de l’inhibiteur du cycle cellulaire Kip-Related Protein, et son rôle durant le développement du fruit. Identification de motifs protéiques fonctionnels chez l’Inhibiteur de Kinase Cycline-Dependent SlKRP1 chez Solanum lycopersicum : Leur rôle dans les interactions avec des partenaires du cycle cellulaire Les
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30

Lubini, Greice. "Caracterização do Gene NtCDKG;2 Expresso no Pistilo de Nicotiana tabacum L." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/17/17135/tde-22042013-141248/.

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A biologia da reprodução sexual de plantas é um campo de pesquisa de grande importância, já que a maioria dos alimentos consumidos pelo homem é composta de partes reprodutivas das plantas (frutos e sementes), oriundas do desenvolvimento de partes do pistilo fertilizado. Em Nicotiana tabacum, identificou-se um gene específico de estigma/estilete, SCI1 (Stigma/style Cell-cycle Inhibitor 1), que atua na inibição da proliferação celular (DePaoli et al., 2011). Através de ensaios de pull-down, verificou-se a interação da proteína SCI1 com uma proteína quinase dependente de ciclina (CDK) (Strin
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31

Brundin, Carl. "Alternative energy concepts for Swedish wastewater treatment plants to meet demands of a sustainable society." Thesis, Umeå universitet, Institutionen för tillämpad fysik och elektronik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-146831.

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This report travels through multiple disciplines to seek innovative and sustainable energy solutions for wastewater treatment plants. The first subject is a report about increased global temperatures and an over-exploitation of natural resources that threatens ecosystems worldwide. The situation is urgent where the current trend is a 2°C increase of global temperatures already in 2040. Furthermore, the energy-land nexus becomes increasingly apparent where the world is going from a dependence on easily accessible fossil resources to renewables limited by land allocation. A direction of the requ
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Koch, Garance. "Effet du stress hydrique sur la croissance de la tomate : une étude multi-échelle : de la cellule à la plante entière pour une meilleure compréhension des interactions entre les différentes échelles." Thesis, Avignon, 2018. http://www.theses.fr/2018AVIG0347.

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Comme pour les autres organes multicellulaires, la croissance et le développement de la feuille et du fruit sont caractérisés par la coordination de la division et de l'expansion des cellules qui sont des processus majeurs de la croissance. Les cellules du péricarpe du fruitcharnu connaissent également des endocycles successifs entrainant ainsi une augmentationimportante de la ploïdie des cellules. Il existe un lien évident entre la croissance cellulaire etl'endoréduplication, cependant, celui-ci est encore mal connu du point de vue fonctionnel. Lesprocessus cellulaires interagissent fortement
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33

Weinl, Christina [Verfasser]. "Challenging the plant cell cycle : analysis of key cell cycle regulators in Arabidopsis thaliana / vorgelegt von Christina Weinl." 2005. http://d-nb.info/97680610X/34.

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Chang, Kerong. "Regulatory proteins and genes in plant cell division and differentiation." Phd thesis, 1993. http://hdl.handle.net/1885/142233.

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Chen, Yi-Lun, and 陳宜倫. "Study on a Plant Product, THKM76: Cytotoxicity and Cell Cycle Effect." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/04684269170185130156.

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碩士<br>國立清華大學<br>生命科學系<br>88<br>Many anticancer agents are currently available for clinical therapy, but very few agents are effective against some types of cancer. Fortunately, we have obtained a potential anticancer agent THKM76 from a plant product. In this purpose, we studied the effects of THKM76 on the morphology, cytotoxicity, and cell cycle progression in a human colon adenocarcinoma cell line (RKO) and a human fibroblast cell line (HF). For RKO cells, characteristic morphological changes and drug-induced apoptosis, related to the administration of the cytotoxic agent, were interpreted
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Badelt, Kim. "Location and enzyme activity of the key cell cycle protein p34 ͨ ᵈ ͨ ² in maize". Phd thesis, 1996. http://hdl.handle.net/1885/145964.

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Sakuanrungsirikul, Suchirat. "Cyclic AMP and the Chlamydomonas reinhardtii cell division cycle." Phd thesis, 1991. http://hdl.handle.net/1885/142214.

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Wu, Li-Ping. "Mutational and biochemical analysis of the cell cycle in Chlamydomonas reinhardtii." Phd thesis, 1993. http://hdl.handle.net/1885/142311.

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"Active fraction of licorice inhibits proliferation of lung cancer cells A549 via inducing cell cycle arrest and apoptosis." 2012. http://library.cuhk.edu.hk/record=b5549045.

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肺癌是導致男性死亡的最常見原因以及是排在乳腺癌和結腸癌之後的導致女性死亡的第三大原因。雖然肺癌如此嚴重,但是如今治疗肺癌仍然是一个挑战。現今對肺癌的治療主要集中在化學治療和靶點藥物治療,但是由於這些治療有著很大的副作用和低治愈率,尋找其他的醫學替代方法十分迫切。甘草是其中最常用的中藥,它常常用作食品工業中的甜味劑。以往的研究表明,甘草具有多種的生物活性。但是甘草提取物對於肺癌的治療卻是十分匱乏的。<br>本論文主要目的是評價甘草提取物以及其中的有效成份對非小型肺癌細胞株A549 的影響,以及其作用的機理。我們的數據表明,甘草的乙酸乙酯(EAL)成份比甘草的乙醇提取物有著比較強的抑制癌細胞的作用。另外,對甘草的五個單體進行的測試中發現lico-3 是最具有抑制肺癌作用的。利用高效液相色譜法對甘草活性成份分析表明,lico-3 是EAL中的其中一個單體。<br>乳酸脫氫酶滲漏(LDH)的檢測結果以及异硫氰酸荧光素-碘化丙啶(FITC-PI)雙染的結果表明,EAL 能夠引起肺癌細胞的凋亡現象而非壞死現象。實驗結果表明由EAL引起的A549細胞凋亡是跟Bcl-2家族及Caspase家族有關係,同時EAL還能夠抑制Akt途徑從而導致細胞的死亡。<br>致肺癌細胞死亡的原因進行進一步研究表明,EAL還能夠引起抑制細胞週期的運作,停留在G2/M 時期。這可能是由於EAL引發了p53與p21的上調
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Liu, Bo. "Cell-Cycle Engineering And Gfp-Online Monitoring Of Heterologous Protein Production In High Density Plant Suspension Cultures." Thesis, 2005. http://hdl.handle.net/10125/10513.

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41

Jordan, Chad Victor. "Geminivirus-induced gene silencing as a method to determine the role of essential cell cycle genes in plant development." 2005. http://www.lib.ncsu.edu/theses/available/etd-05182005-011034/unrestricted/etd.pdf.

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42

Nadal, Marina. "Exploring the role of autophagy and cell wall degrading enzymes in the life cycle and pathogenic development of the basidiomycete fungal plant pathogen Ustilago maydis." 2009. http://purl.galileo.usg.edu/uga%5Fetd/nadal%5Fmarina%5F200912%5Fphd.

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43

Carmichael, Jeremy Paddon. "Strategies for cloning cell division cycle genes in plants." Phd thesis, 1990. http://hdl.handle.net/1885/141097.

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44

DiasBaltazar, Miguel Ângelo. "Cytogenetic and biochemical characterization of the progeny of plants of bread wheat ‘Jordão’ biofortified with Iron and/or Zinc." Master's thesis, 2020. http://hdl.handle.net/10348/9980.

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Dissertação de Mestrado em Genética Molecular Comparativa e Tecnológica<br>Seed priming with micronutrients (nutripriming) has several agronomic advantages if performed with suitable dosages. Nutripriming has been commonly used in the biofortification of crops such as bread wheat (Triticum aestivum L. em Thell.). However, the usage of excessive amounts of micronutrients like Iron (Fe) and Zinc (Zn) can induce cytotoxicity (traceable by both cytogenetic and biochemical analyses) and phytotoxicity (detectable upon the characterization of yield-related components). Nutripriming is performed in ea
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Taniwiryono, Darmono. "Analyses of haploid cells in the life cycle of the plant pathogenic fungus Armillaria mellea." 1993. http://catalog.hathitrust.org/api/volumes/oclc/29968851.html.

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Abraham, Ambily. "Chimeric Virus Like Particles as Nanocarriers for Antibody Delivery in Mammalian Cells & Role of Groundnut Bud Necrosis Virus NSs in Viral Life Cycle." Thesis, 2015. http://etd.iisc.ac.in/handle/2005/3987.

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Knowledge of the dissociation constants of the ionizable protons of weak acids in aqueous media is of fundamental importance in many areas of chemistry and biochemistry. The pKa value, or equilibrium dissociation constant, of a molecule determines the relative concentration of its protonated and deprotonated forms at a specified pH and is therefore an important descriptor of its chemical reactivity. Considerable efforts have been devoted to the determination of pKa values by different experimental techniques. Although in most cases the determination of pKa values from experimental is straightforw
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47

Abraham, Ambily. "Chimeric Virus Like Particles as Nanocarriers for Antibody Delivery in Mammalian Cells & Role of Groundnut Bud Necrosis Virus NSs in Viral Life Cycle." Thesis, 2015. http://etd.iisc.ernet.in/2005/3920.

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Abstract:
Knowledge of the dissociation constants of the ionizable protons of weak acids in aqueous media is of fundamental importance in many areas of chemistry and biochemistry. The pKa value, or equilibrium dissociation constant, of a molecule determines the relative concentration of its protonated and deprotonated forms at a specified pH and is therefore an important descriptor of its chemical reactivity. Considerable efforts have been devoted to the determination of pKa values by different experimental techniques. Although in most cases the determination of pKa values from experimental is straightforw
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