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Relevant bibliographies by topics / Plant cytotoxicity / Dissertations / Theses

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Dissertations / Theses on the topic 'Plant cytotoxicity'

Author: Grafiati

Published: 19 February 2023

Last updated: 20 February 2023

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1

Lindholm, Petra. "Cytotoxic Compounds of Plant Origin – Biological and Chemical Diversity." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-5728.

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2

Lamola, Makgabo Stella. "Antimicrobial activity and cytotoxicity of extracts and an isolated compound from the edible plant Grewia flava against four enteric pathogens." Diss., University of Pretoria, 2015. http://hdl.handle.net/2263/52021.

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Bacterial infections of the gastrointestinal tract (GIT) causes vomiting, diarrhoea and even systemic infection. There is resistance to the commonly used antibiotics used to combat bacterial infection; there is a need for development of natural products into alternative and safer medicines. Studies have been conducted on the other species of the genus Grewia and there are reports of pharmacologically active compounds. There are no published studies up to date on Grewia flava. This study evaluated the antimicrobial activity of extracts prepared from berries, leaves, bark and roots of the edibl

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3

Bendová, Agáta. "Příprava bioaktivních krytů ran a testování jejich interakce s lidskými buňkami." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2019. http://www.nusl.cz/ntk/nusl-401867.

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The thesis was focused on the preparation and optimization of the preparation of wound dressing from materials with bioactive ingredients. In this work were prepared nanofiber dressings based on polyhydroxybutyrate and non-fibrous dressings from alginate and chitosan. Nanofibers were prepared by electrospinning and forcespinning methods. The bioactive components, which were used to functionalize the prepared dressings, were plant extracts, clotrimazole, ampicillin, lysozyme, and proteolytic enzymes. The theoretical part is focused on the description of the use of nanofibrous and non-fibrous ma

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4

Assis, Maria Angélica de Sá. "Ação antimicrobiana e citotoxicidade de extratos aquoso e glicólico de própolis sobre bactérias anaeróbias de importância odontológica /." São José dos Campos, 2018. http://hdl.handle.net/11449/180563.

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Orientador: Luciane Dias de Oliveira<br>Banca: Luis Felipe das Chagas e Silva de Carvalho<br>Banca: Jônatas Rafael de Oliveira<br>Resumo: As plantas medicinais e os fitoterápicos têm sido utilizados como coadjuvantes e alternativos no combate a diversas doenças com crescente frequência, no entanto, na Odontologia seu uso ainda é bastante limitado. Com isso, o objetivo deste estudo é avaliar a ação antimicrobiana dos extratos aquoso e glicólico de própolis verde sobre micro-organismos anaeróbios de interesse odontológico, bem como sua citotoxicidade, a fim de introduzir e incentivar o uso efeti

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5

Akter, Raushanara. "Isolation and Structural Elucidation of Bioactive Compounds from Bangladeshi Medicinal Plants with a Focus on Novel Anticancer Compounds." Thesis, Griffith University, 2014. http://hdl.handle.net/10072/366507.

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The present study describes the bioactivity guided isolation and structural elucidation of novel anticancer compounds from the Bangladeshi medicinal plant Blumera lacera. At the outset nineteen Bangladeshi medicinal plants were selected and collected from different parts of Bangladesh. Plants underwent preliminary cytotoxicity screening based on their traditional medicinal uses, limited previous research on them, and their availability. The selected plants were extracted with methanol and screened for their cytotoxic potential using the MTT assay against two healthy cell lines (mouse fibroblas

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6

Uzu, Gaëlle. "Spéciation, transfert vers les végétaux et approche toxicologique des émissions atmosphériques d'une usine de recyclage de plomb." Thesis, Toulouse, INPT, 2009. http://www.theses.fr/2009INPT008A/document.

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Depuis la révolution industrielle en Europe (XIXe siècle), les nombreuses activités anthropiques ont provoqué des changements environnementaux globaux considérables. La composition de l'atmosphère terrestre en particulier, a été fortement modifiée par l'émission de polluants gazeux et particulaires. Actuellement, l'industrie métallurgique de seconde fusion contribue de façon significative aux émissions atmosphériques de métaux. C'est pourquoi ce travail de thèse s'est focalisé sur l'étude des transferts et impacts sur les sols, les végétaux et l'homme, des particules émises par le procédé de r

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7

Miller, Andrew B. "Antimicrobial and Anticancer Activity of Essential Oils from Guatemalan Medicinal Plants." BYU ScholarsArchive, 2010. https://scholarsarchive.byu.edu/etd/2411.

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Guatemalan medicinal plants were collected and screened for the presence of essential oils using steam distillation. Oil was found in 63 species from 24 families and was tested in tube dilution assays for activity against Escherichia coli, Staphylococcus aureus, Streptococcus mutans, Lactobacillus acidophilus and Candida albicans. Several essential oils were highly active with 20 instances of oils inhibiting the microbes at an MIC of 0.31 µl/ml. Oils were also tested against cancerous and established cell lines using a 15% (v/v) agar-media which was developed to improve essential oil solubilit

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8

Marques, Milene Bueno. "Triagem fitoquímica e avaliação da sensibilidade antimicrobiana e da genotoxicidade de Sedum praealtum DC. (Bálsamo)." Universidade Jose do Rosario Vellano, 2015. http://tede2.unifenas.br:8080/jspui/handle/jspui/102.

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Made available in DSpace on 2016-05-02T13:55:21Z (GMT). No. of bitstreams: 1 Milene Bueno Marques-Dissertacao.pdf: 825475 bytes, checksum: cd33a50c8ba95cbc3e9504abcf1d976c (MD5) Previous issue date: 2015-02-25<br>Sedum praealtum DC. (Crassulaceae) is one of 350 species pharmacologically active from the genus Sedum, whose actions in treatment of eyes (pain and swelling) and ulcer, inflammatory problems, as contraception and anti-fertilization, antinociceptive and anti-inflammatory have been reported. The objective was to evaluate the hydroethanolic extract of S. praealtum regarding their pote

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9

Sekhoacha, Mamello. "Antimalarial activity and cytotoxicity of some South African medicinal plants and their active constituents." Doctoral thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/3300.

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10

Deng, Ye. "Bioactive Constituents of Two Medicinal Plants from Indonesia." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1274289346.

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11

Janse, van Rensburg Catharina Scholtz. "In vitro evaluation of antioxidant properties of Rosa roxburghii plant extract / Catharina Scholtz Janse van Rensburg." Thesis, North-West University, 2003. http://hdl.handle.net/10394/191.

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Rosa roxburghii, also known as "Burr Rose" or "Chestnut Rose", originated in southwest China and was introduced to the botanic garden in Calcutta around 1824. It was named after William Roxburgh who was the superintendent. The extract of fruit of the Rosa roxburghii plant is the base ingredient of a range of products that is commercially sold under the Cili Bao label. The extract is composed of a wide range of substances of nutritional value, in particular a relatively high amount of antioxidants such as ascorbate and plant phenols. It has been reported before that supplementation with the fru

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12

Maja, Matshidiso Patricia. "In Vitro cytotoxicity and antibacterial activity of selected South African medicinal plants used in the treatment of periodontitis." Diss., University of Pretoria, 2009. http://hdl.handle.net/2263/24855.

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The use of medicinal plants in the treatment of infectious diseases is an acceptable and popular phenomenon in South Africa and worldwide. The potential of extracts from these plants as antimicrobial agents necessitates their scientific evaluation. Therefore, this study evaluated the antimicrobial activity of Carpobrotus edulis; Cotyledon orbiculata; Datura stramonium; Dodonaea angustifolia; and Zanthoxylum capense against Porphyromonas gingivalis; Tannerella forsythensis and Actinobacillus actinomycetemcomitan. Given that most currently used drugs are cytotoxic, the possible cytotoxic effect

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13

Uddin, Shaikh Jamal. "Cytotoxicity Screening of Bangladeshi Medicinal Plants and Isolation and structural Elucidation of Novel Anti-Cancer Compounds from Acrostichum aureum." Thesis, Griffith University, 2011. http://hdl.handle.net/10072/365889.

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This thesis describes the cytotoxicity and phytochemical screening of 16 selected medicinal plants collected from the tidal forests of the coastal Sundarban and locations within the Khulna district of Bangladesh. The selected plants were successively extracted with n-hexane, dichloromethane, methanol and water. The methanol and aqueous extracts were then screened for cytotoxic activity (MTT assay) against one normal mouse fibroblast and three human cancer cell lines (gastric, colon and breast cancer). The results supported some of the traditional uses and reported cytotoxic activity for some o

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14

Babajide, Jelili Olalekan. "Chemical and biological investigation into some selected African indigenous medicinal plants." Thesis, University of the Western Cape, 2009. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_7625_1297404173.

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<p>African medicinal plants are commonly used throughout Africa to treat a variety of ailments including wounds and ulcers, cough and chest complaints, gingivitis, fever and gonorrhoea, indication all related to infection and inflammation. In screening several plant species from an inventory of common medicinal plants from both South and West Africa for diverse medicinal purposes, 6 plants were selected because of their interesting and useful ethnomedicinal values.</p>

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15

Odeyemi, Samuel Wale. "A comparative study of the in vitro antidiabetic properties, cytotoxicity and mechanism of action of Albuca bracteata and Albuca setosa bulb extracts." Thesis, University of Fort Hare, 2015. http://hdl.handle.net/10353/3154.

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The search for cheap, non toxic and readily available antidiabetic drugs has been a challenge for researchers and the pharmaceutical industries. Diabetes mellitus is a metabolic disease characterized by defects in the synthesis of insulin and/or insensitivity to the action of insulin at the target cells. The disease has been on the increase mostly in developing countries where large proportions of the population have little access to good medical care due to either accessibility or non availability of synthetic drugs. This has led to the use of medicinal plants to treat diabetes because it is

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16

Pimentel, Vanessa Nascimento. "Liquen plano oral e doença do enxerto contra o hospedeiro cronica da mucosa oral = analise histologica e imuno-histoquimica." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/311046.

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Orientador: Maria Leticia Cintra<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas<br>Made available in DSpace on 2018-08-15T17:26:59Z (GMT). No. of bitstreams: 1 Pimentel_VanessaNascimento_M.pdf: 2864833 bytes, checksum: 3ee9e69bb5f58fae7867132642bdf6e6 (MD5) Previous issue date: 2010<br>Resumo: O líquen plano oral (LPO) e o acometimento oral da doença do enxerto contra o hospedeiro crônica (DECHc) apresentam características clínicas e histológicas semelhantes, apesar da etiologia distinta. A apoptose, induzida por linfócitos T citotóxicos, tem sid

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17

Monteiro, Maria Cristina. "Cytogenotoxicity of chromium and cadmium in plants and in human cells." Doctoral thesis, Universidade de Aveiro, 2016. http://hdl.handle.net/10773/18613.

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Doutoramento em Biologia<br>Os metais têm sido alvo de preocupação devido à sua persistência no ambiente e potencial toxicidade para os seres vivos, após a atividade humana desmensurada. Nesta tese é dada relevância ao Cr e ao Cd, considerados metais poluentes prioritários. Assim, o objetivo do trabalho foi avaliar e compreender os efeitos cito- e genotóxicos putativamente induzidos por sais de Cr e Cd em plantas e células humanas. O Capítulo 1 expõe as fontes de poluição de Cr e Cd, os seus efeitos tóxicos para os seres vivos e mecanismos de absorção a nível celular em plantas e humano

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18

Khiralla, Afra. "Études phytochimique, cytotoxique et antibactérienne de champignons endophytes issus de plantes médicinales du Soudan." Thesis, Université de Lorraine, 2015. http://www.theses.fr/2015LORR0159/document.

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Pour la première fois, l’étude de la flore fongique endophytique de cinq plantes médicinales soudanaises : Calotropis procera (Ait.), Catharanthus roseus (L.), Euphorbia prostrata (Ait.), Trigonella foenum-graecum (L.), and Vernonia amygdalina (Del.) a été réalisée. Un total de 23 souches de champignons endophytes ont été isolées à partir des plantes après la stérilisation de surface puis les différentes analyses biologiques ont été effectuées. Les extraits bruts d’acétate d’éthyle de 21 endophytes ainsi que de leurs plantes hôtes ont été évalués pour leur teneur en phénols totaux et leur acti

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Guedes, Alessandra da Silva. "Contribuição ao estudo farmacognóstico das espécies medicinais Averrhoa bilimbi L. e Poiretia bahiana C. Muller." reponame:Repositório Institucional da UFBA, 2009. http://www.repositorio.ufba.br/ri/handle/ri/9868.

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Submitted by Ana Hilda Fonseca (anahilda@ufba.br) on 2013-04-09T15:57:22Z No. of bitstreams: 1 Dissertação Alessandra (4).pdf: 2685859 bytes, checksum: 5365f2b719ecbda7464c4a77b11585ec (MD5)<br>Approved for entry into archive by Ana Hilda Fonseca(anahilda@ufba.br) on 2013-04-18T17:37:07Z (GMT) No. of bitstreams: 1 Dissertação Alessandra (4).pdf: 2685859 bytes, checksum: 5365f2b719ecbda7464c4a77b11585ec (MD5)<br>Made available in DSpace on 2013-04-18T17:37:08Z (GMT). No. of bitstreams: 1 Dissertação Alessandra (4).pdf: 2685859 bytes, checksum: 5365f2b719ecbda7464c4a77b11585ec (MD5) Previous i

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20

Talag, Agela Hussain Mohammed. "Phytochemical investigation and biological activities of Sanicula europaea and Teucrium davaeanum : isolation and identification of some constituents of Sanicula europaea and Teucrium davaeanum and evaluation of the antioxidant activity of ethanolic extracts of both plants and cytotoxic activity of some isolated compounds." Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/14482.

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The aim of this research was to investigate the phytochemistry of two species Sanicula europaea and Teucrium davaeanum which are traditionally used in treatment of wounds. Four compounds were isolated from the 80% methanolic extract of S. europaea; bis-(2-ethylhexyl) phthalate (1), palmitic acid (2), rosmarinic acid (3), saniculoside N (4). Compounds 1 and 2 were isolated for the first time from this species. The structure elucidation of the isolated compounds was on the basis of 1D, 2D NMR spectroscopy and mass spectrometry measurements. Two compounds were isolated from the crude glycosides e

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Silva, Filho Eliezer Fernandes da. "Avaliação tóxica, citotóxica e mutagênica de extratos aquosos de Ipomoea asarifolia (Convolvulaceae)." Universidade Federal Rural do Semi-Árido, 2015. http://bdtd.ufersa.edu.br:80/tede/handle/tede/792.

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Submitted by Lara Oliveira (lara@ufersa.edu.br) on 2017-08-08T21:47:01Z No. of bitstreams: 1 EliezerFSF_DISSERT.pdf: 825442 bytes, checksum: 4e1f858f4401bb5bd1feb35cb8a2ae1e (MD5)<br>Approved for entry into archive by Vanessa Christiane (referencia@ufersa.edu.br) on 2017-08-17T22:39:18Z (GMT) No. of bitstreams: 1 EliezerFSF_DISSERT.pdf: 825442 bytes, checksum: 4e1f858f4401bb5bd1feb35cb8a2ae1e (MD5)<br>Approved for entry into archive by Vanessa Christiane (referencia@ufersa.edu.br) on 2017-08-17T22:41:48Z (GMT) No. of bitstreams: 1 EliezerFSF_DISSERT.pdf: 825442 bytes, checksum: 4e1f858f4401bb5

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Mbeng, Wilfred Otang. "Antifugal evaluation and phytochemical analysis of selected medicinal plants used in the treatment of fungal diseases associated with HIV infection in the Eastern Cape Province, South Africa." Thesis, University of Fort Hare, 2013. http://hdl.handle.net/10353/d1006834.

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Background. As a result of the AIDS pandemic, many people areimmuno compromised andopportunistic fungal infections (OFIs) such as candidiasis are common. Despite the widespread use of medicinal plants in South Africa, there is a dearth of knowledge regarding the use of such plants in the management of these infections. This study evaluates three South African medicinal plants (Arctotis arctotoides, Pittosporum viridiflorum, and Gasteria bicolor) traditionally used in the treatment of OFIs in HIV/AIDS patients, in the Eastern Cape Province, South Africa. Materials and methods. A six-stage proce

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Peixoto, Iza Teixeira Alves. "Atividade antimicrobiana do óleo essencial de diferentes acessos de Mentha spp. contra Candida albicans e Candida dubliniensis." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289367.

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Orientadores: José Francisco Hofling, Marta Cristina Teixeira Duarte<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia<br>Made available in DSpace on 2018-08-17T21:24:04Z (GMT). No. of bitstreams: 1 Peixoto_IzaTeixeiraAlves_D.pdf: 4732148 bytes, checksum: cd8cbf98531ac28e12f9feba2f8edd34 (MD5) Previous issue date: 2010<br>Resumo: O objetivo desse estudo foi avaliar a ação antimicrobiana de óleos essenciais e frações de diferentes acessos de Mentha spp. contra Candida spp., identificando seus compostos e verificando sua citotoxicidade. Os 64 óleos essenciais de

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Silva, Viviane Araújo da. "Avaliação citotóxica e genotóxica de Mimosa tenuiflora (Willd.) Poir. (Mimosaceae)." Universidade Federal da Paraíba, 2012. http://tede.biblioteca.ufpb.br:8080/handle/tede/6722.

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Made available in DSpace on 2015-05-14T12:59:31Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 1623079 bytes, checksum: 1db342a9defb06c8f56de918c6d74da7 (MD5) Previous issue date: 2012-02-13<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES<br>Mimosa tenuiflora (Willd.) Poir., popularly known as Jurema preta, is a plant family Mimosaceae, found mainly in the states of Piauí, Ceará, Rio Grande do Norte, Paraiba, Pernambuco, Alagoas, Sergipe and Bahia, which this species is typical of semi-arid areas of Brazil. In folk medicine, the bark of the stem is the main part of t

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Carvalho, José Carlos Borges de. "Estudo químico e biológico das espécies vegetais caboverdianas Echium hypertropicum Webb e Echium stenosiphon Webb subsp. Stenosiphon." Niterói, 2017. https://app.uff.br/riuff/handle/1/3281.

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Submitted by Biblioteca da Faculdade de Farmácia (bff@ndc.uff.br) on 2017-04-04T17:26:03Z No. of bitstreams: 1 Carvalho, José Carlos Borges de [Dissertação, 2013].pdf: 4019706 bytes, checksum: 84b0655827cda5d4ea9ce98d03f1736c (MD5)<br>Made available in DSpace on 2017-04-04T17:26:03Z (GMT). No. of bitstreams: 1 Carvalho, José Carlos Borges de [Dissertação, 2013].pdf: 4019706 bytes, checksum: 84b0655827cda5d4ea9ce98d03f1736c (MD5)<br>Echium hypertropicum Webb e Echium stenosiphon Webb subsp. stenosiphon são arbustos endêmicos de Cabo Verde, usados na medicina popular para o tratamento de dis

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Oliveira, Aline Mylena Guedes da Costa. "Avalia??o da atividade antimal?rica e citot?xica de plantas medicinais dos Biomas Caatinga e Amaz?nico." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13074.

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Made available in DSpace on 2014-12-17T14:10:24Z (GMT). No. of bitstreams: 1 AlineMGCO_DISSERT.pdf: 3644884 bytes, checksum: e2e3e578d2fb797531853d76567fdc2b (MD5) Previous issue date: 2011-03-15<br>Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico<br>Resistance of Plasmodium falciparum to the usual antimalarials, as well as their adverse effects and high cost, has led to the search of new drugs against malaria. Several of these have been developed from medicinal plants based on ethnopharmacology, including the most widely used antimalarials today: quinine and artemisinin. In the

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Carvalho, Gabriel Costa de. "Análise do perfil fenotípico e funcional das células natural Killer e linfócitos TCD8+ no Líquen plano." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5133/tde-09082016-164859/.

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INTRODUÇÃO: Líquen plano (LP) é uma doença mucocutânea de natureza inflamatória crônica de etiologia ainda desconhecida. Alterações na resposta imune inata, como aos padrões moleculares associados à patógenos (PAMPs) e padrões moleculares associados ao dano (DAMPs) podem levar à inflamação crônica e contribuir com a patogênese do LP. OBJETIVO: Avaliar o efeito da ativação via o DAMP S100A8 e o receptor Toll-like 4 (TLR-4) em células Natural killer (NK) e TCD8 citotóxicas e suas subpopulações de memória/efetoras em pacientes com LP. MÉTODOS: Foram selecionados 25 pacientes com LP (22 mulheres,

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Rezk, Ahmed Verfasser], Matthias [Akademischer Betreuer] Ullrich, Klaudia [Akademischer Betreuer] [Brix, Nikolai [Akademischer Betreuer] Kuhnert, and Dirk [Akademischer Betreuer] Albach. "From Ethnomedicine to Application: Biological Activities and Cytotoxicity of Leaf Extracts from Plants of the Genus Rhododendron / Ahmed Rezk. Betreuer: Matthias Ullrich ; Klaudia Brix. Gutachter: Matthias Ullrich ; Klaudia Brix ; Nikolai Kuhnert ; Dirk Albach." Bremen : IRC-Library, Information Resource Center der Jacobs University Bremen, 2015. http://d-nb.info/1087325749/34.

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Lima, Maíra Conceição Jeronimo de Souza. "Estudo sobre a toxicidade da Aspidosperma pyrifolium (pereiro)." Universidade Federal Rural do Semi-Árido, 2011. http://bdtd.ufersa.edu.br:80/tede/handle/tede/411.

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Made available in DSpace on 2016-08-15T20:31:37Z (GMT). No. of bitstreams: 1 MairaCJSL_DISSERT.pdf: 420836 bytes, checksum: 822f4cc895779b5cc7c308d8152a664d (MD5) Previous issue date: 2011-02-25<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This study aimed to evaluate the spontaneous cases of poisoning in goats, rats and toxicity in vitro cytotoxicity of Aspidospema pyrifolium. In all spontaneous cases studied, the plant is ingested and the abortion cases occurred exclusively in goats. Most cases of abortion occurred during the dry season and early rainy season, and expe

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Gonçalves, Carolina Lambrecht. "Bacteriostasia, citotoxicidade, atividade antioxidante e sinergismo com antibacterianos comerciais de plantas bioativas com inidicativo medicinal." Universidade Federal de Pelotas, 2014. http://repositorio.ufpel.edu.br:8080/handle/prefix/3029.

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Submitted by Ubirajara Cruz (ubirajara.cruz@gmail.com) on 2016-09-21T12:58:52Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_carolina_goncalves.pdf: 1889685 bytes, checksum: 46a4396ab85d8faec733bba0c7fa0d94 (MD5)<br>Approved for entry into archive by Aline Batista (alinehb.ufpel@gmail.com) on 2016-09-21T16:28:31Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) dissertacao_carolina_goncalves.pdf: 1889685 bytes, checksum: 46a4396ab85d8faec733bba0c7fa0d94 (MD5)<br>Made available in DSpace o

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Carvalho, Nayane Chagas. "Análise da citotoxicidade e genocitoxicidade da Aloe vera associada a medicamento endodôntico e fotobiomodulação a laser." Universidade Federal de Sergipe, 2016. https://ri.ufs.br/handle/riufs/5909.

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This study aims to evaluate the effect of a drug in order to avoid the appearance of side effects of human pulp fibroblasts. The groups were divided into: CTR with culture medium with fibroblasts; CL, FTL only; AA, Aloe vera with distilled water; AL, Aloe vera with distilled water and FTL; HA, calcium hydroxide P.A. With distilled water; HL, calcium hydroxide P.A. With distilled water and FTL; HAA, calcium hydroxide P.A. With Aloe vera and distilled water; HAL, calcium hydroxide P.A. With Aloe vera, distilled water and FTL. Cytotoxicity evaluation was performed with the MTT reagent at 24, 48 a

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Vasconcelos, Inácio Ricardo Alves. "Investigação dos efeitos antibacteriano, antioxidante, citotóxico e genotóxico do óleo essencial do caule de Croton tricolor Klotzsch ex Baill." Universidade Federal da Paraíba, 2015. http://tede.biblioteca.ufpb.br:8080/handle/tede/8639.

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Submitted by Márcio Maia (marciokjmaia@gmail.com) on 2016-09-08T20:43:23Z No. of bitstreams: 1 arquivototal.pdf: 1314156 bytes, checksum: 53176e3b5e1286467ff179df2731a8da (MD5)<br>Made available in DSpace on 2016-09-08T20:43:23Z (GMT). No. of bitstreams: 1 arquivototal.pdf: 1314156 bytes, checksum: 53176e3b5e1286467ff179df2731a8da (MD5) Previous issue date: 2015-08-26<br>The use of natural products by man goes back to the origins of the human species, which over the evolutionary process, was learning how to select plants for their food and for the relief of their ailments and diseases. E

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Lima, Rafaely Nascimento. "Caracterização química dos óleos essenciais e extratos supercríticos de três espécies de Piper de Sergipe." Pós-Graduação em Química, 2014. https://ri.ufs.br/handle/riufs/6097.

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To contribute to the knowledge of the chemical species P. klotzschianum, P. hispidum and P. arboreum, analyzes of volatile obtained by hydrodistillation-(HD), extracts obtained by supercritical fluid extraction-(SFE) and identification of isolated compounds were performed using techniques such as GC/MS/FID, NMR (1D, 2D) and IV. Sesquiterpenes present in P. klotzschianum, P. hispidum and P. arboreum as the (E)-caryophyllene, bicyclogermacrene and germacrene D observed only in P.hispidum and P. klotzschianum were the main substances responsible for the high values obtained sesquiterpenes identif

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Erdelyi, Maria Carolina. "Contribuição à farmacognosia de Annona squamosa L. (Annonaceae) - Acompanhamento da variação sazonal de constituintes, aspectos botânicos e avaliação da atividade antileishmania in vitro." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/9/9138/tde-14092017-114936/.

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As doenças tropicais endêmicas representam um grave problema sócio-econômico, no Brasil e no mundo. A leishmaniose insere-se neste quadro. Considerando o surgimento da resistência dos parasitas e a séria toxicidade da terapêutica convencional, a busca de novas alternativas é urgente. A família Annonaceae tem mostrado ser rica fonte de compostos com atividade antiprotozoária. Neste contexto, Annona squamosa L. foi selecionada. Sendo mais conhecida como \"fruta-do-conde\", apresenta uso na medicinal popular, como: antihelmíntica e no combate aos ectoparasitas. Entre os principais metabólitos sec

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AHMAD, NURIE AHMAD. "Contribution a l'etude de la croissance et de la toxinogenese du genre fusarium (link) sur mais apres recolte." Nantes, 1986. http://www.theses.fr/1986NANT2036.

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La premiere partie des travaux a porte sur la mise au point des methodes permettant le dosage de cinq toxines du groupe des trichothecenes. Les methodes mises au point concernent les toxines responsables de contaminations naturelles; t2-toxine, ht2-toxine, t2-tetraol, diacetoxyscirpenol, deoxynivalenol. L'etude de modalites des biosyntheses de ces toxines a ete precedee de differents essais preliminaires: une trentaine de souches, appartenant a une dizaine d'especes fusariennes frequentes sur mais en france, ont ete examinees pour leur aptitude a la synthese des trichothecenes. Deux especes ca

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DERRIEN, Anne-Cécile. "Synthèse et caractérisation physico-chimique de matériaux géopolymères. Application : cinétique de minéralisation de géopolymères et du biomatériau CaCO3 synthétique." Phd thesis, Université Rennes 1, 2004. http://tel.archives-ouvertes.fr/tel-00007911.

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Dans le domaine de la chirurgie orthopédique ou maxillo-faciale, les praticiens sont confrontés à des pertes de substance osseuse qui nécessitent l'utilisation de matériaux de comblement (ou de substitution). L'utilisation de biomatériaux synthétiques (dont la disponibilité est très importante) permet de limiter les réponses immunitaires. Dans ce travail nous nous intéressons à deux matériaux : les géopolymères et le carbonate de calcium synthétique sous forme d'aragonite pure. Dans le domaine des biomatériaux de comblement, l'optimisation du compromis entre le pourcentage de porosité et les p

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Chen, Yi-Lun, and 陳宜倫. "Study on a Plant Product, THKM76: Cytotoxicity and Cell Cycle Effect." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/04684269170185130156.

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碩士<br>國立清華大學<br>生命科學系<br>88<br>Many anticancer agents are currently available for clinical therapy, but very few agents are effective against some types of cancer. Fortunately, we have obtained a potential anticancer agent THKM76 from a plant product. In this purpose, we studied the effects of THKM76 on the morphology, cytotoxicity, and cell cycle progression in a human colon adenocarcinoma cell line (RKO) and a human fibroblast cell line (HF). For RKO cells, characteristic morphological changes and drug-induced apoptosis, related to the administration of the cytotoxic agent, were interpreted

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Wu, Tzu-Min, and 吳慈敏. "Size Distributions and Cytotoxicity of Ambient Aerosols Collected Near a Semiconductor Plant." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/45715067978685890933.

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碩士<br>國立屏東科技大學<br>環境工程與科學系所<br>100<br>In this study, PS-1, Dichot, MOUDIs and Nano-MOUDIs were used to collect TSP, PM2.5-10, PM2.5, PM0.01-10 (as PM10 thereafter), PM0.01-2.5 (as PM2.5), PM0.01-1 (as PM1.0), PM0.01-0.1 (as PM0.1) and PM0.01-0.056 (as PM0.056) samples on the rooftops of a semiconductor plant and a wastewater treatment plant (48.9 and 16 m high, respectively) (from March to September, 2011) in a Southern Taiwan Science Park to characterize the size distributions of sampled particles and the cytotoxicity of particle extracts. In addition to the analyses of particulate water-solu

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Chou, Chi-Jung, and 周奇蓉. "Studies on the Chemical Constituents and Cytotoxicity of the Seeds of Formosan Annonaceous Plant - Annona muricata." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/21728336200448344316.

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碩士<br>高雄醫學大學<br>天然藥物研究所<br>88<br>Twenty eight compounds including twenty mono-THF ring acetogenins, annonacin (1), annonacinone (2), annomontacin (3), cis- annomontacin (4), xylopiacin (5), murisolin (6), muricatetrocin A (7) & B (8), muricin A (9), muricin B (10), muricin C (11), muricin D (12), muricin E (13)、muricin F (14), muricin G (15), longifolicin (16), corossolin (17), corossolone (18), muricin H (19) and muricin I (20), one adjacent bis-THF rings acetogenin, annocatacin B (21), one linear acetogenin, cohibin A (22), one epoxyl acetogenin, epomuricin (23), one amide, N-palmitryltrypta

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Taiwo, Bamigboye J., Amos A. Fatokun, O. O. Olubiyi, O. T. Bamigboye-Taiwo, Heerden F. R. van, and Colin W. Wright. "Identification of compounds with cytotoxic activity from the leaf of the Nigerian medicinal plant, Anacardium occidentale L. (Anacardiaceae)." 2017. http://hdl.handle.net/10454/11940.

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Yes<br>Cancer is now the second-leading cause of mortality and morbidity, behind only heart disease, necessitating urgent development of (chemo)therapeutic interventions to stem the growing burden of cancer cases and cancer death. Plants represent a credible source of promising drug leads in this regard, with a long history of proven use in the indigenous treatment of cancer. This study therefore investigated Anacardium occidentale, one of the plants in a Nigerian Traditional Medicine formulation commonly used to manage cancerous diseases, for cytotoxic activity. Bioassay-guided fraction

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Félix, Carina Rafaela Faria da Costa. "Multi-omics approach to study responses to temperature in Lasiodiplodia theobromae, a human and plant fungal pathogen." Doctoral thesis, 2018. http://hdl.handle.net/10773/26082.

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Lasiodiplodia theobromae is a phytopathogenic fungus considered an aggressive pathogen, especially for some crops, and has also been associated to opportunistic human infections. Small environmental alterations, such as the increasing of the global temperature, can have a huge impact on the dynamic between hosts and their pathogens, leading to changes in virulence or even to the colonization of different hosts. Thus, the main goal of this work was to characterize the molecular mechanisms of pathogenicity of L. theobromae under increasing temperatures. To achieve this, a multi-omics appr

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Adewusi, Emmanuel Adekanmi. "In vitro effect of selected medicinal plants on β-amyloid induced toxicity in neuroblastoma cells". Thesis, 2012. http://hdl.handle.net/2263/28325.

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Neurodegenerative diseases occur as a result of the breakdown and deterioration of the neurons of the central nervous system (CNS). They are commonly found in elderly people and are a major cause of morbidity and mortality, thereby imposing severe strains on the social welfare systems. Alzheimer’s disease (AD) is the most common age-related neurodegenerative disorder. Cholinergic deficit, senile plaque/amyloid-β peptide deposition and oxidative stress have been identified as three main pathogenic pathways which contribute to the progression of AD. The current therapeutic options cause several

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Thorburn, Anzelle. "Phytochemical analysis and antimicrobial activity of Piper capensis L.f." Diss., 2011. http://hdl.handle.net/2263/25752.

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Medicinal plants are the focus of intense study, in particular whether their traditional uses are supported by real pharmacological effects, or merely based on folklore. Piper capense L.f. (Piperaceae) is used traditionally for the treatment of infectious diseases, and has the potential to be a source of novel antimicrobial compound(s). Crude solvent extracts (water, methanol, hexane and acetone) and sequentially extracted subfractions of the root-bark of P. capense were prepared, of which the hexane-soluble subfraction MsAsHs was identified as the most promising antimicrobial subfraction. Phy

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AnilaKumar, K. R. "Studies on the effect of plant foods on antioxidant enzyme system and their influnce on the chemically induced cytotoxicity in rats." Thesis, 2002. http://hdl.handle.net/2009/1430.

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Mishra, Ritu. "Mechanism of Abrin-Induced Apoptosis and Insights into the Neutralizing Activity of mAb D6F10." Thesis, 2014. http://hdl.handle.net/2005/2787.

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Abrin is a potent toxin obtained from the seeds of Abrus precatorius. It is a heterodimeric glycoprotein consisting of an A and a B subunit linked together by a disulfide bond. The toxicity of the protein comes from the A subunit harboring RNA-N-glycosidase activity which cleaves the glycosidic bond between the ribose sugar and the adenine at position 4324 in 28S rRNA. The depurination of a specific adenine residue at position 4324 results in loss of conformation of the 28S rRNA at the α sarcin/ricin loop to which elongation factor-2 (EF-2) binds, during the transloction step of translation, l

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peng, Hui-Hsuan, and 彭惠鉉. "Evaluation of cytotoxicity, mutagenicity and antimutagenicity of nine non-traditionally edible plants." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/35828413540347641141.

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碩士<br>國立中興大學<br>食品科學系<br>85<br>The Ames test was used to evaluate the toxic, mutagenic, and antimutagenic effects from edible parts of nine non- traditionally edible plants, including Crassocephalum creidioides S. Moore (Cra), Sechium americanum Poir (Sec), Portulaca oleracea L. (Por), Boussingaultia gracilis Miers var. (Bou), Corchorus capsularis L. (Cor), Centella asiatica L. Urban (Cen), Solanum nigrum L. (Sol), Basella rubra L. (Bas), and Anisogonium esculentum Presl (Ani). Comet assay

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Tshikalange, T. E. (Thilivhali Emmanuel). "In vitro anti-HIV-1 properties of ethnobotanically selected South African plants used in the treatment of sexually transmitted diseases." Thesis, 2008. http://hdl.handle.net/2263/26030.

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Yang, Mei-Hsin, and 楊美欣. "Analysis and Study on the Free Radical Scavenging and Cytotoxicity of Human Breast Cancer Tumor Cell Lines for the Methanol Extracts of Coastal Plants." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/9aab9n.

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碩士<br>國立虎尾科技大學<br>生物科技研究所<br>100<br>The coastal plants refer to the plants growing in the coastal areas. Due to the harsh climate and geographical environments, the coastal plants developed various forms of special construction and physiological mechanisms to adapt to the environment, including the complicated colorful patterns, wind preventive, drought resistant, and salt tolerant features. The aim of this study is to investigate the coastal medicinal plants in Taiwan for the development of medicines and preservation of the plant resources. After the practical investigation, plant materials c

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Mboweni, Hlayisa Fredah. "Antimicrobial, cytotoxic and prelimenary phytochemical analysis of four medicinal plants and their formulation." Diss., 2018. http://hdl.handle.net/11602/1096.

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MSc (Microbiology)<br>Department of Microbiology<br>BACKGROUND: Medicinal plants form an important part of the Southern African cultural heritage. Indigenous populations, for example the Vha-Venda people, tend to use medicinal plants in formulations rather than western medicines for health and survival. In order to certify and give scientific credibility to the use of medicinal plants formulations used by Vha-Venda people for the treatment of diseases, several assays were carried out. The present study was aimed at assessing phytochemical content, antimicrobial, antioxidant and cytotoxic

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Chowdhury, Abu Khayer Md Muktadirul Bari. "Composting of agro-industrial wastes." Thesis, 2014. http://hdl.handle.net/10889/8573.

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The olive oil extraction industry represents a substantial share of the economies of Mediterranean countries but leads to serious environmental problems by producing huge amounts of wastes (by-products) within a short production period. The production rate of olive oil is about 1.4-1.8 million tonnes per year in the Mediterranean, resulting in 30 million m3 of by-products and 20 million tonnes of olive pomace. A small portion of these wastes can be used as raw materials in different industries as they contain valuable natural resources. Greece has about 2300 small-scale, rural, agro-industrial

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