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Journal articles on the topic 'Plant stem cells'

Author: Grafiati
Published: 24 April 2022

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1

Voronina, A. S., and E. S. Pshennikova. "Plant Stem Cells." Molecular Biology 54, no. 2 (March 2020): 163–77. http://dx.doi.org/10.1134/s002689332002017x.

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2

Greb, Thomas, and Jan U. Lohmann. "Plant Stem Cells." Current Biology 26, no. 17 (September 2016): R816—R821. http://dx.doi.org/10.1016/j.cub.2016.07.070.

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3

Perez-Garcia, Pablo, and Miguel A. Moreno-Risueno. "Stem cells and plant regeneration." Developmental Biology 442, no. 1 (October 2018): 3–12. http://dx.doi.org/10.1016/j.ydbio.2018.06.021.

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4

Sang, Ya Lin, Zhi Juan Cheng, and Xian Sheng Zhang. "Plant stem cells andde novoorganogenesis." New Phytologist 218, no. 4 (March 25, 2018): 1334–39. http://dx.doi.org/10.1111/nph.15106.

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5

Dodueva, I. E., V. E. Tvorogova, M. Azarakhsh, M. A. Lebedeva, and L. A. Lutova. "Plant stem cells: unity and diversity." Vavilov Journal of Genetics and Breeding 20, no. 4 (January 1, 2016): 441–58. http://dx.doi.org/10.18699/vj16.172.

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6

Dodueva, I. E., V. E. Tvorogova, M. Azarakhsh, M. A. Lebedeva, and L. A. Lutova. "Plant stem cells: Unity and diversity." Russian Journal of Genetics: Applied Research 7, no. 4 (June 2017): 385–403. http://dx.doi.org/10.1134/s2079059717040025.

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7

Scheres, Ben. "Stem Cells: A Plant Biology Perspective." Cell 122, no. 4 (August 2005): 499–504. http://dx.doi.org/10.1016/j.cell.2005.08.006.

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8

Wu, Haijun, Xiaoya Qu, Zhicheng Dong, Linjie Luo, Chen Shao, Joachim Forner, Jan U. Lohmann, et al. "WUSCHEL triggers innate antiviral immunity in plant stem cells." Science 370, no. 6513 (October 8, 2020): 227–31. http://dx.doi.org/10.1126/science.abb7360.

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Stem cells in plants constantly supply daughter cells to form new organs and are expected to safeguard the integrity of the cells from biological invasion. Here, we show how stem cells of the Arabidopsis shoot apical meristem and their nascent daughter cells suppress infection by cucumber mosaic virus (CMV). The stem cell regulator WUSCHEL responds to CMV infection and represses virus accumulation in the meristem central and peripheral zones. WUSCHEL inhibits viral protein synthesis by repressing the expression of plant S-adenosyl-l-methionine–dependent methyltransferases, which are involved in ribosomal RNA processing and ribosome stability. Our results reveal a conserved strategy in plants to protect stem cells against viral intrusion and provide a molecular basis for WUSCHEL-mediated broad-spectrum innate antiviral immunity in plants.
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9

G, Subramanyam, Himakar Reddy K, and Mahaboob V. Shaik. "Mobilization of Stem Cells Using Plant Extracts." Stem Cell & Regenerative Medicine 2, no. 2 (December 30, 2018): 1–4. http://dx.doi.org/10.33425/2639-9512.1030.

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10

Singh, Mohan B., and Prem L. Bhalla. "Plant stem cells carve their own niche." Trends in Plant Science 11, no. 5 (May 2006): 241–46. http://dx.doi.org/10.1016/j.tplants.2006.03.004.

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11

Albert, E. V., and T. A. Ezhova. "Genetic regulation of plant shoot stem cells." Russian Journal of Genetics 49, no. 2 (February 2013): 127–40. http://dx.doi.org/10.1134/s1022795413020026.

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12

Wild, Jennifer. "Overview of Plant Stem Cells in Cosmeceuticals." Plastic Surgical Nursing 34, no. 3 (2014): 148–49. http://dx.doi.org/10.1097/psn.0000000000000050.

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13

Batygina, T. B., and I. V. Rudskii. "Role of stem cells in plant morphogenesis." Doklady Biological Sciences 410, no. 1 (October 2006): 400–402. http://dx.doi.org/10.1134/s0012496606050164.

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14

PI, LiMin, YuXian ZHU, and YuanZheng LIU. "Antiviral innate immunity in plant stem cells." SCIENTIA SINICA Vitae 51, no. 1 (December 3, 2020): 102–4. http://dx.doi.org/10.1360/ssv-2020-0371.

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15

Pierre-Jerome, Edith, Colleen Drapek, and Philip N. Benfey. "Regulation of Division and Differentiation of Plant Stem Cells." Annual Review of Cell and Developmental Biology 34, no. 1 (October 6, 2018): 289–310. http://dx.doi.org/10.1146/annurev-cellbio-100617-062459.

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A major challenge in developmental biology is unraveling the precise regulation of plant stem cell maintenance and the transition to a fully differentiated cell. In this review, we highlight major themes coordinating the acquisition of cell identity and subsequent differentiation in plants. Plant cells are immobile and establish position-dependent cell lineages that rely heavily on external cues. Central players are the hormones auxin and cytokinin, which balance cell division and differentiation during organogenesis. Transcription factors and miRNAs, many of which are mobile in plants, establish gene regulatory networks that communicate cell position and fate. Small peptide signaling also provides positional cues as new cell types emerge from stem cell division and progress through differentiation. These pathways recruit similar players for patterning different organs, emphasizing the modular nature of gene regulatory networks. Finally, we speculate on the outstanding questions in the field and discuss how they may be addressed by emerging technologies.
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16

Kong, Lingbo. "Plant-Derived Compounds in Regulating Bone Stem Cells." Current Stem Cell Research & Therapy 15, no. 1 (March 19, 2020): 3. http://dx.doi.org/10.2174/1574888x1501200206121632.

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17

Heidstra, Renze, and Sabrina Sabatini. "Plant and animal stem cells: similar yet different." Nature Reviews Molecular Cell Biology 15, no. 5 (April 23, 2014): 301–12. http://dx.doi.org/10.1038/nrm3790.

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18

Kofuji, Rumiko, Yasushi Yagita, Takashi Murata, and Mitsuyasu Hasebe. "Antheridial development in the moss Physcomitrella patens : implications for understanding stem cells in mosses." Philosophical Transactions of the Royal Society B: Biological Sciences 373, no. 1739 (December 18, 2017): 20160494. http://dx.doi.org/10.1098/rstb.2016.0494.

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Stem cells self-renew and produce precursor cells that differentiate to become specialized cell types. Land plants generate several types of stem cells that give rise to most organs of the plant body and whose characters determine the body organization. The moss Physcomitrella patens forms eight types of stem cells throughout its life cycle. Under gametangium-inducing conditions, multiple antheridium apical stem cells are formed at the tip of the gametophore and each antheridium apical stem cell divides to form an antheridium. We found that the gametophore apical stem cell, which typically forms leaf and stem tissues, changes to become a new type of stem cell, which we term the antheridium initial stem cell. This antheridium initial stem cell produces multiple antheridium apical stem cells, resulting in a cluster of antheridia at the tip of gametophore. This is the first report of a land plant stem cell directly producing another type of stem cell during normal development. Notably, the antheridium apical stem cells are distally produced from the antheridium initial stem cell, similar to the root cap stem cells of vascular plants, suggesting the use of similar molecular mechanisms and a possible evolutionary relationship. This article is part of a discussion meeting issue ‘The Rhynie cherts: our earliest terrestrial ecosystem revisited’.
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19

Palmberg, Irmeli. "Stem cells in microturbellarians." Protoplasma 158, no. 3 (October 1990): 109–20. http://dx.doi.org/10.1007/bf01323123.

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20

Czajkowski, Robert, Waldo J. de Boer, Johannes A. van Veen, and Jan M. van der Wolf. "Downward Vascular Translocation of a Green Fluorescent Protein-Tagged Strain of Dickeya sp. (Biovar 3) from Stem and Leaf Inoculation Sites on Potato." Phytopathology® 100, no. 11 (November 2010): 1128–37. http://dx.doi.org/10.1094/phyto-03-10-0093.

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Translocation of a green fluorescent protein (GFP)-tagged Dickeya sp. from stems or from leaves to underground parts of potato plants was studied in greenhouse experiments. Thirty days after stem inoculation, 90% of plants expressed symptoms at the stem base and 95% of plants showed browning of internal stem tissue. The GFP-tagged Dickeya sp. was detected by dilution plating in extracts of the stem interiors (100%), stem bases (90%), roots (80%), stolons (55%), and progeny tubers (24%). In roots, the GFP-tagged Dickeya sp. was found inside and between parenchyma cells whereas, in stems and stolons, the GFP-tagged Dickeya sp. was found in the xylem vessels and protoxylem cells. In progeny tubers, this strain was detected in the stolon end. Thirty days after leaf inoculation, the GFP-tagged Dickeya sp. was detected in extracts of 75% of the leaves, 88% of the petioles, 63% of the axils, and inside 25% of the stems taken 15 cm above the ground level. UV microscopy confirmed the presence of the GFP-tagged Dickeya sp. inside petioles and in the main leaf veins. No blackleg or aerial stem rot and no translocation of the GFP-tagged Dickeya sp. to underground plant parts was observed. The implications for contamination of progeny tubers are discussed.
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21

Nishang, Liu, Liu Yulin, and Ma Yinyue. "Research progress of natural plant products inducing apoptosis of tumor stem cells." E3S Web of Conferences 292 (2021): 03068. http://dx.doi.org/10.1051/e3sconf/202129203068.

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Compared to general cancer cells, cancer stem cells are stronger and more difficult to be killed by drugs. Therefore, traditional treatment methods have low efficacy according to cancer stem cells. In essence, one of the main causes of cancer survival, proliferation, transfer, and recurrence is the presence of cancer stem cells. In recent years, a large number of studies have demonstrated that natural plant products have powerful in killing cancer cells and have various structures, which possess low toxicity, multi-target regulation advantages in inducing cancer stem cells to apoptosis. Therefore, this provides new ideas for developing anti-cancer drugs by inducing cancer stem cell apoptosis by natural plant products. In this article, we will introduce the apoptotic mechanism of tumor stem cells, the importance of eliminating tumor stem cells, and the benefits of natural plant products in cancer treatment. In addition, this paper reviewed nine categories of chemicals in natural plant products that induce apoptosis of tumor stem cells and their mechanisms of action. We also summarized the mechanism of natural plant products inducing apoptosis of tumor stem cells. This review provides an important reference for the personalized treatment of cancer.
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22

Sengupta, Shouvonik, Moni Philip Jacob Kizhakedathil, and Deepa P. Sankar. "Plant Stem Cells-Regulation and Applications: A Brief Review." Research Journal of Pharmacy and Technology 11, no. 4 (2018): 1535. http://dx.doi.org/10.5958/0974-360x.2018.00286.x.

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23

Doerner, Peter. "Plant stem cells: The only constant thing is change." Current Biology 10, no. 22 (November 2000): R826—R829. http://dx.doi.org/10.1016/s0960-9822(00)00791-0.

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24

VERDEIL, J., L. ALEMANNO, N. NIEMENAK, and T. TRANBARGER. "Pluripotent versus totipotent plant stem cells: dependence versus autonomy?" Trends in Plant Science 12, no. 6 (June 2007): 245–52. http://dx.doi.org/10.1016/j.tplants.2007.04.002.

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25

Sablowski, Robert. "Plant and animal stem cells: conceptually similar, molecularly distinct?" Trends in Cell Biology 14, no. 11 (November 2004): 605–11. http://dx.doi.org/10.1016/j.tcb.2004.09.011.

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26

Fujimoto, Masaru, Takashi Sazuka, Yoshihisa Oda, Hiroyuki Kawahigashi, Jianzhong Wu, Hideki Takanashi, Takayuki Ohnishi, et al. "Transcriptional switch for programmed cell death in pith parenchyma of sorghum stems." Proceedings of the National Academy of Sciences 115, no. 37 (August 27, 2018): E8783—E8792. http://dx.doi.org/10.1073/pnas.1807501115.

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Pith parenchyma cells store water in various plant organs. These cells are especially important for producing sugar and ethanol from the sugar juice of grass stems. In many plants, the death of pith parenchyma cells reduces their stem water content. Previous studies proposed that a hypothetical D gene might be responsible for the death of stem pith parenchyma cells in Sorghum bicolor, a promising energy grass, although its identity and molecular function are unknown. Here, we identify the D gene and note that it is located on chromosome 6 in agreement with previous predictions. Sorghum varieties with a functional D allele had stems enriched with dry, dead pith parenchyma cells, whereas those with each of six independent nonfunctional D alleles had stems enriched with juicy, living pith parenchyma cells. D expression was spatiotemporally coupled with the appearance of dead, air-filled pith parenchyma cells in sorghum stems. Among D homologs that are present in flowering plants, Arabidopsis ANAC074 also is required for the death of stem pith parenchyma cells. D and ANAC074 encode previously uncharacterized NAC transcription factors and are sufficient to ectopically induce programmed death of Arabidopsis culture cells via the activation of autolytic enzymes. Taken together, these results indicate that D and its Arabidopsis ortholog, ANAC074, are master transcriptional switches that induce programmed death of stem pith parenchyma cells. Thus, targeting the D gene will provide an approach to breeding crops for sugar and ethanol production.
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27

Krüger, H., A. Viljoen, and P. S. Van Wyk. "Histopathology of Albugo tragopogonis on stems and petioles of sunflower." Canadian Journal of Botany 77, no. 1 (June 1, 1999): 175–78. http://dx.doi.org/10.1139/b99-016.

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Stem lesions in sunflower caused by Albugo tragopogonis (Pers.) S.F. Gray developed individually from primary infections and did not result from a systemic infection. Cell division and callose formation were not observed, but weak lignin deposition occurred in infected tissues. Hyphae occurred intercellularly in stems in the cortex, cambium, vascular rays, and pith. In petioles parenchymatous tissue was heavily colonized in contrast to lightly colonized collenchymatous hypodermis. The middle lamellae of cells in infected tissue were dissolved, and cells degenerated and eventually collapsed. Stem infections lead to deterioration of tissue integrity, weakening of stems, and finally to lodging of stems (breaking over).Key words: Albugo tragopogonis, Helianthus annuus, histopathology, stem lodging.
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28

Davamani, V., E. Parameswari, S. Arulmani, P. Doraisamy, J. S. Kennedy, and M. Maheswari. "Evaluation of localization of lead and nickel in plant cells of Amaranthus sp. and Brassica sp. absorbed from mine spoil waste." Journal of Applied and Natural Science 8, no. 3 (September 1, 2016): 1611–14. http://dx.doi.org/10.31018/jans.v8i3.1009.

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A detailed survey was undertaken in the sewage water contaminated areas of Coimbatore to select the natural hyper accumulators to rehabilitate the contaminated mine spoils. From this experiment the Pb and Ni accumulators, Amaranthus sp. and Brassica sp. were selected for further studies towards remediating the metal contaminated mine spoils. Microtomy of root, stem and leaf of Amaranthus sp. and Brassica sp. showed that the colour development in the plant species is evidence for accumulation of metals in different parts of plants and also tolerance mechanism employed by plant species under metal stress condition. The accumulation of heavy metals from soil to plant did not follow any particular pattern and varied with respect to metals, species and plant parts. However, the maximum Pb localization took place in root portion than in aerial parts. But the Ni accumulation was almost equal or higher in aerial parts (leaf and stem) compared to roots. This study revealed that the Amaranthus sp and Brassica sp stored lead and nickel in roots, leaves and stems. The roots showed more localization of metals followed by leaves and stems.
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29

Motte, Hans, Boris Parizot, Tao Fang, and Tom Beeckman. "The evolutionary trajectory of root stem cells." Current Opinion in Plant Biology 53 (February 2020): 23–30. http://dx.doi.org/10.1016/j.pbi.2019.09.005.

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30

Miastkowska, Małgorzata, and Elżbieta Sikora. "Anti-Aging Properties of Plant Stem Cell Extracts." Cosmetics 5, no. 4 (September 22, 2018): 55. http://dx.doi.org/10.3390/cosmetics5040055.

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Skin aging is a complex process which involves all the layers of the epidermis and dermis. In order to slow skin aging, methods are researched which would strengthen and protect skin stem cells. Science is in search of the right method to stimulate the proliferation of epidermal stem cells. Plant stem cells show outstanding anti-aging properties, as they can, among other activities, stimulate fibroblasts to synthesise collagen, which, in turn, stimulates skin regeneration. One of the most important agents which give anti-aging properties to plant stem cell extracts is kinetin (6-furfuryladenine). This compound belongs to a cytokine group and is considered to be a strong antioxidant which protects protein and nucleic acids from oxidation and glycoxidation processes. It enables cells to remove the excess of free radicals to protect them from oxidative stress.
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31

Wang, Xiaoting, Uddhab Karki, Hasara Abeygunaratne, Carmela UnnoldCofre, and Jianfeng Xu. "Plant cell-secreted stem cell factor stimulates expansion and differentiation of hematopoietic stem cells." Process Biochemistry 100 (January 2021): 39–48. http://dx.doi.org/10.1016/j.procbio.2020.09.029.

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32

Rieu, Ivo, and Thomas Laux. "Signaling pathways maintaining stem cells at the plant shoot apex." Seminars in Cell & Developmental Biology 20, no. 9 (December 2009): 1083–88. http://dx.doi.org/10.1016/j.semcdb.2009.09.013.

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33

Dijkwel, Paul P., and Alvina G. Lai. "Hypothesis: Plant stem cells hold the key to extreme longevity." Translational Medicine of Aging 3 (2019): 14–16. http://dx.doi.org/10.1016/j.tma.2018.12.002.

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34

Sablowski, R. "Cytokinin and WUSCHEL tie the knot around plant stem cells." Proceedings of the National Academy of Sciences 106, no. 38 (September 15, 2009): 16016–17. http://dx.doi.org/10.1073/pnas.0909300106.

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35

Prhal, Jelena, Jela Milic, Danina Krajisnik, and Gordana Vuleta. "Properties and use of plant stem cells in cosmetic products." Arhiv za farmaciju 64, no. 1 (2014): 26–37. http://dx.doi.org/10.5937/arhfarm1401026p.

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36

Zhou, Jing, Jose Sebastian, and Ji-Young Lee. "Signaling and gene regulatory programs in plant vascular stem cells." genesis 49, no. 12 (October 13, 2011): 885–904. http://dx.doi.org/10.1002/dvg.20795.

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37

Zhou, Jing, Jose Sebastian, and Ji-Young Lee. "Signaling and gene regulatory programs in plant vascular stem cells." genesis 49, no. 12 (December 2011): spcone. http://dx.doi.org/10.1002/dvg.20830.

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38

Trehan, Sonia, Bozena Michniak-Kohn, and Kavita Beri. "Plant stem cells in cosmetics: current trends and future directions." Future Science OA 3, no. 4 (November 2017): FSO226. http://dx.doi.org/10.4155/fsoa-2017-0026.

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39

Warghat, Ashish R., Kanika Thakur, and Archit Sood. "Plant stem cells: what we know and what is anticipated." Molecular Biology Reports 45, no. 6 (September 8, 2018): 2897–905. http://dx.doi.org/10.1007/s11033-018-4344-z.

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40

Liu, Chun-Ming, and Yuxin Hu. "Plant stem cells and their regulations in shoot apical meristems." Frontiers in Biology 5, no. 5 (October 2010): 417–23. http://dx.doi.org/10.1007/s11515-010-0880-1.

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41

Aggarwal, Srishti, and Amrish Chandra. "An insight into patent landscape analysis of plant stem cells." World Patent Information 65 (June 2021): 102025. http://dx.doi.org/10.1016/j.wpi.2021.102025.

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42

Best, Violet M., Archana Vasanthakumar, and Patricia S. McManus. "Anatomy of Cranberry Stem Gall and Localization of Bacteria in Galls." Phytopathology® 94, no. 11 (November 2004): 1172–77. http://dx.doi.org/10.1094/phyto.2004.94.11.1172.

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Cranberry stem gall is characterized by tumors that girdle stems, thereby killing all distal leaves, flowers, and fruit. Bacteria that produce high levels of the plant growth hormone indole-3-acetic acid (IAA) are associated with and believed to cause cranberry stem gall. The anatomy of naturally occurring galls on woody cranberry plants and galls caused by inoculation of micropropagated cranberry plants with Pantoea agglomerans strain 4/99 was consistent with elevated levels of IAA in plants. Field galls exhibited hypertrophy and hyperplasia of tissue external to the vascular cambium, resulting in extensive stem swelling and splitting of the periderm. Similarly, galls on micropropagated plants contained enlarged cortical parenchyma cells. The current year's xylem vessels in field galls were narrow and dense compared with xylem vessels of healthy stems. Curved xylem elements apparently developed de novo within field galls and galls on inoculated plants. Cavities and fissures in both types of galls contained dense aggregates of bacteria. Treatment of micropropagated plants with synthetic IAA caused hypertrophy of cortical parenchyma and formation of adventitious roots. The results support the hypothesis that IAA-producing bacteria cause cranberry stem gall.
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43

Xue, Wenqing, Jinhua Yu, and Wu Chen. "Plants and Their Bioactive Constituents in Mesenchymal Stem Cell-Based Periodontal Regeneration: A Novel Prospective." BioMed Research International 2018 (August 5, 2018): 1–15. http://dx.doi.org/10.1155/2018/7571363.

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Periodontitis is a common chronic inflammatory disease, which causes the destruction of both the soft and mineralized tissues. However, current treatments such as bone graft materials, barrier membranes, and protein products all have difficulties in regenerating the complete periodontal tissue structure. Stem cell-based tissue engineering has now emerged as one of the most effective treatments for the patients suffering from periodontal diseases. Plants not only can be substrates for life processes, but also contain hormones or functional molecules. Numbers of preclinical studies have revealed that products from plant can be successfully applied in modulating proliferation and differentiation of human mesenchymal stem cells. Plant-derived substances can induce stem cells osteogenic differentiation, and they also possess angiogenic potency. Furthermore, in the field of tissue engineering, plant-derived compounds or plant extracts can be incorporated with biomaterials or utilized as biomaterials for cell transplantation. So it is speculated that botanical products may become a new perspective in stem cell-based periodontal regeneration. However, the lack of achieving predict clinical efficacy and quality control has been the major impediment to its extensive application. This review gives an overview of the prospect of applying different plant-derived substances in various human mesenchymal stem cells-based periodontal regeneration.
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44

Antonio Alonso, Alexandre, and Silvia Rodrigues Machado. "Stem Protective Tissue in Erythroxylum Tortuosum (Erythroxylaceae), A Fire Tolerant Species from Cerrado." IAWA Journal 29, no. 1 (2008): 69–77. http://dx.doi.org/10.1163/22941932-90000171.

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The origin and structure are described of the secondary protective tissue in the stem of Erythorxylum tortuosum Mart., a fire tolerant shrubby species common in Brazilian cerrado. The highly tortuous stems are covered with thick bark which is more developed at the base of the stem. After fire in the cerrado, rhytidome fragments of the burned stem flake off, revealing newly formed cork. The first periderm appears near of the terminal buds and is iniated by periclinal divisions in subepidermal cells giving rise to radial rows of cells. The first phellogen is discernible only after the differentiation of the several radial rows of cork cells. Other phellogens have their origin in successively deeper layers of the cortex. The sucessive periderms are discontinuous around the circumference. The collapsed cells with phenolic substances and the accumulated dead cells cause the formation of discontinuous blackish lines, which delimit the sucessive periderms in the rhytidome. The rhytidome contains large quantities of sclereids developed from cell wall thickening of cortex cells. The occurrence of periderm in the young parts of the stem and of rhytidome in the older parts represents pyrophytic characteristics and may explain, in part, the fire tolerance of this species.
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45

Machado, Silvia Rodrigues, Carmen Regina Marcati, Berta Lange de Morretes, and Veronica Angyalossy. "Comparative Bark Anatomy of Root and Stem in Styrax Camporum (Styracaceae)." IAWA Journal 26, no. 4 (2005): 477–87. http://dx.doi.org/10.1163/22941932-90000129.

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The bark of Styrax camporum Pohl (Styracaceae) differs anatomically in the root and stem. Roots have layered secondary phloem; short sieve tubes with simple, transverse or more or less inclined sieve plates; fibres in tangential bands; astrosclereids; wide rays, and a poorly developed periderm. Stems have non-layered secondary phloem; longer sieve tubes with compound, scalariform, inclined sieve plates; sclerified cells and brachysclereids; a developed periderm, and a non-persistent rhytidome. Prismatic crystals, starch grains, phenolic compounds and lipidic contents were observed in root and stem bark cells. The differences between the secondary phloem of root and stem are discussed.
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46

Janocha, Denis, and Jan U. Lohmann. "From signals to stem cells and back again." Current Opinion in Plant Biology 45 (October 2018): 136–42. http://dx.doi.org/10.1016/j.pbi.2018.06.005.

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47

Nishikawa, Shin-Ichi, and Masatake Osawa. "Generating quiescent stem cells." Pigment Cell Research 20, no. 4 (August 2007): 263–70. http://dx.doi.org/10.1111/j.1600-0749.2007.00388.x.

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48

Gupta, Piyush, Mrunmayee Saraff, Rekha Gahtori, Nidhi Negi, Surya Tripathi, Jatin Kumar, Sanjay Kumar, et al. "Phytomedicines Targeting Cancer Stem Cells: Therapeutic Opportunities and Prospects for Pharmaceutical Development." Pharmaceuticals 14, no. 7 (July 15, 2021): 676. http://dx.doi.org/10.3390/ph14070676.

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The presence of small subpopulations of cells within tumor cells are known as cancer stem cells (CSCs). These cells have been the reason for metastasis, resistance with chemotherapy or radiotherapy, and tumor relapse in several types of cancers. CSCs underwent to epithelial–mesenchymal transition (EMT) and resulted in the development of aggressive tumors. CSCs have potential to modulate numerous signaling pathways including Wnt, Hh, and Notch, therefore increasing the stem-like characteristics of cancer cells. The raised expression of drug efflux pump and suppression of apoptosis has shown increased resistance with anti-cancer drugs. Among many agents which were shown to modulate these, the plant-derived bioactive agents appear to modulate these key regulators and were shown to remove CSCs. This review aims to comprehensively scrutinize the preclinical and clinical studies demonstrating the effects of phytocompounds on CSCs isolated from various tumors. Based on the available convincing literature from preclinical studies, with some clinical data, it is apparent that selective targeting of CSCs with plants, plant preparations, and plant-derived bioactive compounds, termed phytochemicals, may be a promising strategy for the treatment of relapsed cancers.
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49

Liskova, Alena, Peter Kubatka, Marek Samec, Pavol Zubor, Milos Mlyncek, Tibor Bielik, Samson Mathews Samuel, Anthony Zulli, Taeg Kyu Kwon, and Dietrich Büsselberg. "Dietary Phytochemicals Targeting Cancer Stem Cells." Molecules 24, no. 5 (March 4, 2019): 899. http://dx.doi.org/10.3390/molecules24050899.

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There is an increasing awareness of the importance of a diet rich in fruits and vegetables for human health. Cancer stem cells (CSCs) are characterized as a subpopulation of cancer cells with aberrant regulation of self-renewal, proliferation or apoptosis leading to cancer progression, invasiveness, metastasis formation, and therapy resistance. Anticancer effects of phytochemicals are also directed to target CSCs. Here we provide a comprehensive review of dietary phytochemicals targeting CSCs. Moreover, we evaluate and summarize studies dealing with effects of dietary phytochemicals on CSCs of various malignancies in preclinical and clinical research. Dietary phytochemicals have a significant impact on CSCs which may be applied in cancer prevention and treatment. However, anticancer effects of plant derived compounds have not yet been fully investigated in clinical research.
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50

S, Jana. "Impact of the Trivedi Effect ® - Energy of Consciousness Healing on the Proliferation of Plant, Mouse and Human Stem Cells." Journal of Embryology & Stem Cell Research 3, no. 1 (2019): 1–8. http://dx.doi.org/10.23880/jes-16000115.

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