Academic literature on the topic 'Plasmacytoïde dendritic cells'

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Journal articles on the topic "Plasmacytoïde dendritic cells"

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Jegalian, Armin G., Fabio Facchetti, and Elaine S. Jaffe. "Plasmacytoid Dendritic Cells." Advances in Anatomic Pathology 16, no. 6 (2009): 392–404. http://dx.doi.org/10.1097/pap.0b013e3181bb6bc2.

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Waller, Edmund K. "Mobilizing plasmacytoid dendritic cells." Blood 129, no. 19 (2017): 2600–2602. http://dx.doi.org/10.1182/blood-2017-03-774703.

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Maroso, Mattia. "Depleting plasmacytoid dendritic cells." Science 372, no. 6545 (2021): 929.17–929. http://dx.doi.org/10.1126/science.372.6545.929-q.

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Smit, Joost J., Brian D. Rudd, and Nicholas W. Lukacs. "Plasmacytoid dendritic cells inhibit pulmonary immunopathology and promote clearance of respiratory syncytial virus." Journal of Experimental Medicine 203, no. 5 (2006): 1153–59. http://dx.doi.org/10.1084/jem.20052359.

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Respiratory syncytial virus (RSV) infection is widely spread and is a major cause of bronchiolitis in infants and high-risk adults, often leading to hospitalization. RSV infection leads to obstruction and inflammation of the airways and induction of innate and acquired immune responses. Because dendritic cells (DCs) are essential in the elicitation of these immune responses, we investigated the presence and the role of dendritic cell subtypes upon RSV infection in the lung. Here, we report that RSV infection increased the number of both conventional and plasmacytoid dendritic cells in the lung
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Weslow-Schmidt, Janet L., Nancy A. Jewell, Sara E. Mertz, J. Pedro Simas, Joan E. Durbin, and Emilio Flaño. "Type I Interferon Inhibition and Dendritic Cell Activation during Gammaherpesvirus Respiratory Infection." Journal of Virology 81, no. 18 (2007): 9778–89. http://dx.doi.org/10.1128/jvi.00360-07.

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ABSTRACT The respiratory tract is a major mucosal site for microorganism entry into the body, and type I interferon (IFN) and dendritic cells constitute a first line of defense against viral infections. We have analyzed the interaction between a model DNA virus, plasmacytoid dendritic cells, and type I IFN during lung infection of mice. Our data show that murine gammaherpesvirus 68 (γHV68) inhibits type I IFN secretion by dendritic cells and that plasmacytoid dendritic cells are necessary for conventional dendritic cell maturation in response to γHV68. Following γHV68 intranasal inoculation, t
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Bardawil, Tara, Samar Khalil, Mazen Kurban, and Ossama Abbas. "Diagnostic utility of plasmacytoid dendritic cells in dermatopathology." Indian Journal of Dermatology, Venereology and Leprology 87 (February 5, 2021): 3–13. http://dx.doi.org/10.25259/ijdvl_638_19.

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Differentiating cutaneous diseases that mimic each other clinically and histopathologically can at times be a challenging task for the dermatopathologist. At the same time, differentiation of entities with overlapping features may be crucial for patient management. Although not seen in normal skin, plasmacytoid dendritic cells usually infiltrate the skin in several infectious, inflammatory/autoimmune and neoplastic entities. Plasmacytoid dendritic cells can be identified in tissue using specific markers such as CD123 and/or blood-derived dendritic cell antigen-2. Plasmacytoid dendritic cells a
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Tassone, Laura, Daniele Moratto, William Vermi, et al. "Defect of plasmacytoid dendritic cells in warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome patients." Blood 116, no. 23 (2010): 4870–73. http://dx.doi.org/10.1182/blood-2010-03-272096.

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Abstract Warts, hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome is a genetic disease that is caused by heterozygous mutations of the CXCR4 gene. These mutations confer an increased leukocyte response to the CXCR4-ligand CXCL12, resulting in abnormal homeostasis of many leukocyte types, including neutrophils and lymphocytes. Analysis of the myeloid and plasmacytoid dendritic cell blood counts in WHIM patients revealed a striking defect in the number of plasmacytoid dendritic cells as well as a partial reduction of the number of myeloid dendritic cells, compared with healthy sub
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Fuchsberger, Martina, Hubertus Hochrein, and Meredith O'Keeffe. "Activation of plasmacytoid dendritic cells." Immunology & Cell Biology 83, no. 5 (2005): 571–77. http://dx.doi.org/10.1111/j.1440-1711.2005.01392.x.

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Colonna, Marco, Giorgio Trinchieri, and Yong-Jun Liu. "Plasmacytoid dendritic cells in immunity." Nature Immunology 5, no. 12 (2004): 1219–26. http://dx.doi.org/10.1038/ni1141.

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Biessen, Erik A. L., and Anette Christ. "Plasmacytoid Dendritic Cells in Atherosclerosis." Circulation 130, no. 16 (2014): 1340–42. http://dx.doi.org/10.1161/circulationaha.114.012641.

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Dissertations / Theses on the topic "Plasmacytoïde dendritic cells"

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Assil, Sonia. "Mechanism of viral immunostimulatory signal transmission from infected cells to plasmacytoid dendritic cells." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSEN069.

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Les cellules dendritiques plasmacytoides (pDCs), spécialisées dans la réponse antivirale, produisent de fortes quantités d’interféron (IFN) lorsqu’elles sont en contact avec des cellules infectées par des virus. Pourtant, les pDCs sont réfractaires à l’infection. Ce mécanisme d’activation de la réponse antivirale par le contact physique avec les cellules infectées, nouvellement découvert, constituerait un aspect général des voies de défense de l’hôte contre les virus.En utilisant le virus de l’Hépatite C et de la Dengue comme modèle viral, nous avons observé une réorganisation moléculaire au n
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Ceroi, Adam. "Les "Liver X Receptors" : modulateurs des fonctions des cellules dendritiques plasmocytoïdes et leur contrepartie leucémique." Thesis, Besançon, 2015. http://www.theses.fr/2015BESA3015/document.

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Chaque cadre doit contenir un résumé de 1700 caractères maximum, espaces compris. En cas de dépassement, la coupure sera automatique. Le doctorant adresse son texte sous forme électronique selon les recommandations de la bibliothèqueLes "Liver X receptors " (LXR) sont des récepteurs nucléaires impliqués dans Phoméostasie du cholestérol. Dans les macrophages, la stimulation de la voie LXR accroît la clairance des corps apoptotiques et réprime la réponse inflammatoire. Les LXR inhibent également la prolifération et la survie de cellules malignes.L'activation des LXR dans les cellules dendritique
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Futsch, Nicolas. "Caractérisation de l’activation des cellules dendritiques plasmacytoïdes par les virus HTLV-1 et HTLV-2 et de son importance dans la symptomatologie viro-induite." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSEN067/document.

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Le virus T-lymphotrope humain de type 1 (HTLV-1) est l’agent étiologique de deux principales pathologies : la leucémie/lymphome à cellules T de l’adulte (ATLL) et la paraparésie spastique tropicale/myélopathie associée à HTLV-1 (HAM/TSP). Ces deux maladies sont caractérisées par des phénotypes immunitaires opposés, puisque l’ATLL est associée à une immunosuppression et l’HAM/TSP à une réponse pro-inflammatoire. Les mécanismes qui déterminent l’évolution de l’infection chronique vers l’une ou l’autre de ces maladies sont peu connus. L’interféron de type 1 (IFN-I) a une fonction ambiguë dans l’o
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Netravali, Ilka Arun. "Elucidation of plasmacytoid dendritic cell development." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11311.

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Most currently defined hematopoietic progenitor pools are heterogeneous, contributing to uncertainty regarding the development of certain blood cells. The origins of plasmacytoid dendritic cells, for instance, have long been controversial and progenitors exclusively committed to this lineage have never been described. We show here that the fate of hematopoietic progenitors is determined in part by their surface levels of 9-O-acetyl sialic acid. Pro-plasmacytoid dendritic cells were identified as lineage negative 9-O-acetyl sialic acid low progenitors that lack myeloid and lymphoid potential
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Kim, Jong-won. "Signalling initiation by blood dendritic cell antigen 2, a novel immunoglobulin receptor on plasmacytoid dendritic cells." Thesis, Imperial College London, 2018. http://hdl.handle.net/10044/1/63862.

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The focus of this project is a human-specific C-type lectin with potential roles in cell signalling: blood dendritic cell antigen 2 (BDCA-2). BDCA-2, a plasmacytoid dendritic cell-specific molecular marker, has been evaluated as a therapeutic target against auto-immune disorders, because antibodies to BDCA-2 inhibit the production of type I interferon. Accordingly, key goals of the project were to identify endogenous ligands for BDCA-2, to characterise the mechanism of ligand binding and ultimately to determine how ligands stimulate signalling pathways. A combination of BDCA-2 affinity chromat
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Seeds, Rosalind E. "Innate recognition of viruses by plasmacytoid dendritic cells." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491973.

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Plasmacytoid dendritic cells (pDCs) are thought to be specialized for early viral recognition and secrete large amounts of the anti-viral cytokines type I interferon (lFNa/f3). This thesis studied viral recognition by pDCs and aimed to identify novel viral sensing receptors for viral glycoproteins. Murine pDCs were found to express the predominantly myeloid restricted lectins (mannose receptor, SIGNRI, Dectin-I and Dectin-2); a scavenger receptor, immunomodulatory receptor-ligand pairs (CD200R, CD200, SIRPa and CD47) and myeloid differentiation antigens (F4/80 and 7/4). This extends the known
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Kawamura, Kazuko. "Virus-stimulated plasmacytoid dendritic cells induce CD4[+] cytotoxic regulatory T cells." Kyoto University, 2006. http://hdl.handle.net/2433/143873.

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Preston, Stephen. "The recruitment of plasmacytoid dendritic cells in DNA vaccination." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497075.

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Singh, Rena. "Phenotypic and functional characterisation of myeloid and plasmacytoid dendritic cells." Thesis, University College London (University of London), 2006. http://discovery.ucl.ac.uk/1446340/.

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Cord blood transplantation (CBT) is an alternative to bone marrow transplantation (BMT) and is associated with a reduced severity of graft versus host disease (GvHD). Recipient and donor dendritic cells (DCs) are involved in the development of GvHD, and two main subsets, myeloid DCs (MDCs) and plasmacytoid DCs (PDCs), with different immunological functions, have been identified in adult peripheral blood (APB). In this thesis, the presence, phenotype and functional characteristics of these two DC subsets were investigated in CB. Absolute cell counts, the expression of a number of markers and th
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Bandoła, Joanna, Cornelia Richter, Martin Ryser, et al. "Neurotrophin Receptor p75NTR Regulates Immune Function of Plasmacytoid Dendritic Cells." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2017. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-230813.

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Plasmacytoid dendritic cells (pDCs) regulate innate and adaptive immunity. Neurotrophins and their receptors control the function of neuronal tissue. In addition, they have been demonstrated to be part of the immune response but little is known about the effector immune cells involved. We report, for the first time, the expression and immune-regulatory function of the low affinity neurotrophin receptor p75 neurotrophin receptor (p75NTR) by the antigen-presenting pDCs, mediated by toll-like receptor (TLR) 9 activation and differential phosphorylation of interferon regulatory factor 3 and 7. The
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Books on the topic "Plasmacytoïde dendritic cells"

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Lane, Andrew A. Blastic Plasmacytoid Dendritic Cell Neoplasm an Issue of Hematology/Oncology Clinics of North America. Elsevier, 2020.

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van der Vlag, Johan, and Jo H. M. Berden. The patient with systemic lupus erythematosus. Edited by Giuseppe Remuzzi. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0161.

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Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with various clinical manifestations. The hallmark of SLE is the presence of antibodies against nuclear constituents, such as double-stranded (ds)DNA, histones, and nucleosomes. Local deposition of antinuclear antibodies in complex with nuclear autoantigens induces serious inflammatory conditions that can affect several tissues and organs, including the kidney.The levels of antinucleosome and anti-dsDNA antibodies seem to correlate with glomerulonephritis and these autoantibodies can often be detected years before the patient
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Book chapters on the topic "Plasmacytoïde dendritic cells"

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Gehrie, Eric, William Van der Touw, Jonathan S. Bromberg, and Jordi C. Ochando. "Plasmacytoid Dendritic Cells in Tolerance." In Methods in Molecular Biology. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-869-0_9.

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Zimmermann, Arthur. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26587-2_87-1.

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Zimmermann, Arthur. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26956-6_87.

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Goyal, Amrita, Joi B. Carter, and Lyn McDivitt Duncan. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Atlas of Cutaneous Lymphomas. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-17217-0_21.

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Cascio, Michael J., and Robert S. Ohgami. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Molecular Pathology Library. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62146-3_18.

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Kempf, Werner. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Rare Malignant Skin Tumors. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-2023-5_70.

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Subtil, Antonio. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Diagnosis of Cutaneous Lymphoid Infiltrates. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-11654-5_43.

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Hudnall, S. David, Melissa A. Much, and Alexa J. Siddon. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Pocket Guide to Diagnostic Hematopathology. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-10630-0_5.

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Miranda, Roberto N., Joseph D. Khoury, and L. Jeffrey Medeiros. "Blastic Plasmacytoid Dendritic Cell Neoplasm." In Atlas of Lymph Node Pathology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7959-8_82.

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O’Brien, Meagan, Olivier Manches, and Nina Bhardwaj. "Plasmacytoid Dendritic Cells in HIV Infection." In Advances in Experimental Medicine and Biology. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-4433-6_3.

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Conference papers on the topic "Plasmacytoïde dendritic cells"

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Cooles, Faye AH, Amy E. Anderson, Dennis W. Lendrem, et al. "01.10 Peripheral blood plasmacytoid dendritic cells in early rheumatoid arthritis." In 37th European Workshop for Rheumatology Research 2–4 March 2017 Athens, Greece. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2016-211048.10.

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Van Pottelberge, Geert R. M., Ken R. Bracke, Sarah Vandenbroeck, et al. "Plasmacytoid Dendritic Cells In Pulmonary Lymphoid Follicles Of Patients With COPD." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3882.

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Zhou, Qiao, Richard Cuthbert, Abdulla Watad, et al. "THU0057 PLASMACYTOID DENDRITIC CELLS IN THE ENTHESIS: PHENOTYPING AND FUNCTION INVESTIGATION." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.4845.

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Sapienza, Maria Rosaria, Fabio Fuligni, Maria Antonella Laginestra, et al. "Abstract 1951: miRNA expression profile of Blastic plasmacytoid dendritic cell neoplasm." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-1951.

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Palomares, O., C. Benito-Villalvilla, X. Jaumont, P. Pfister, P. Tassinari, and J. López-Abente. "Omalizumab Restores the Capacity of Human Plasmacytoid Dendritic Cells to Induce FOXP3+ Regulatory T Cells." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1068.

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Lewkowich, IP, KM Dienger, AA Sproles, JR Clark, and M. Wills-Karp. "Plasmacytoid Dendritic Cells (DC) Limit Myeloid DC Activation, Promoting Resistance to Experimental Asthma." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a6087.

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Vey, Nelly, Elena Blanc, Vanja Sisirak, et al. "Abstract 1109: The antimicrobial peptide LL37 activates plasmacytoid dendritic cells in breast cancer." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-1109.

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Koucký, Vladimír, Kamila Hladíková, Jan Bouček, and Anna Fialová. "Abstract B91: Plasmacytoid dendritic cells in HPV+ and HPV- head and neck cancer." In Abstracts: AACR Special Conference on Tumor Immunology and Immunotherapy; November 27-30, 2018; Miami Beach, FL. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/2326-6074.tumimm18-b91.

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Sapienza, Maria Rosaria, Manuela Ferracin, Fabio Fuligni, et al. "Abstract 1805: Integrative analysis of microRNAs in blastic plasmacytoid dendritic cell neoplasm." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-1805.

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Sapienza, Maria Rosaria, Manuela Ferracin, Fabio Fuligni, et al. "Abstract 1805: Integrative analysis of microRNAs in blastic plasmacytoid dendritic cell neoplasm." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-1805.

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