Journal articles: 'Plasmas froids'

1

-Ricard, A. "Introduction aux plasmas froids." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 82. http://dx.doi.org/10.3845/ree.1998.041.

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Douat, Claire, Thierry Dufour, and João Santos Sousa. "Les plasmas froids et le Vivant, de nouvelles avancées." Reflets de la physique, no. 75 (April 2023): 24–30. http://dx.doi.org/10.1051/refdp/202375024.

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Depuis le début des années 2000, des avancées technologiques majeures ont permis l'émergence de plasmas froids à pression atmosphérique ayant de faibles valeurs de courant et des températures proches de la température ambiante. Dans cet article, nous exposons dans un premier temps les principales sources de plasma froid utilisées avec succès dans les applications biomédicales, en insistant notamment sur les propriétés physico-chimiques recherchées. Dans un second temps, nous proposons un état de l'art des dernières avancées médicales (en particulier en cancérologie et en dermatologie), ainsi qu'en agriculture.

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-Oberlin, Claude. "Les plasmas froids : présentation générale." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 81. http://dx.doi.org/10.3845/ree.1998.040.

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4

Roux, Solène, Nofel Merbahi, and Michel Simon. "Les milieux activés par plasma froid à pression atmosphérique." médecine/sciences 41, no. 1 (2025): 40–46. https://doi.org/10.1051/medsci/2024192.

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Les plasmas froids à pression atmosphérique, des gaz partiellement ionisés, sont utilisés pour diverses applications biomédicales, comme la décontamination des instruments chirurgicaux. Récemment, une méthode dérivée et plus facile à mettre en œuvre a été développée : l’utilisation de milieux activés par plasma froid (PAM). Le traitement des plaies cutanées par PAM semble favoriser leur cicatrisation. Grâce aux espèces réactives de l’oxygène et de l’azote qu’ils contiennent, les PAM stimulent en effet la migration des kératinocytes et des fibroblastes ainsi que l’angiogenèse, des mécanismes essentiels à la cicatrisation, tout en inhibant la prolifération bactérienne.

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Comparat, Daniel, Amodsen Chotia, Matthieu Viteau, Thibault Vogt, and Pierre Pillet. "Aux frontières des plasmas : les plasmas ultra-froids." Reflets de la physique, no. 3 (March 2007): 10–14. http://dx.doi.org/10.1051/refdp/2007038.

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6

Jolly, Jacques. "Diagnostics laser dans les plasmas froids." Journal de Physique III 5, no. 7 (1995): 1089–113. http://dx.doi.org/10.1051/jp3:1995179.

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7

Pouvesle, Jean-Michel, and Éric Robert. "Applications thérapeutiques des plasmas froids atmosphériques." Reflets de la physique, no. 33 (March 2013): 17–22. http://dx.doi.org/10.1051/refdp/201333017.

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8

-Segui, Yvan. "Traitement des polymères par plasmas froids." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 88. http://dx.doi.org/10.3845/ree.1998.043.

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9

-Marode, Emmanuel. "Le traitement des effluents gazeux par plasmas froids." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 99. http://dx.doi.org/10.3845/ree.1998.046.

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10

Boeuf, Jean-Pierre, Benoît Bernecker, Thierry Callegari, Stéphane Blanco, and Richard Fournier. "Phénomènes d’auto-organisation dans les plasmas froids hors équilibre." Reflets de la physique, no. 36 (October 2013): 16–21. http://dx.doi.org/10.1051/refdp/201336016.

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11

Legeay, G., J. J. Rousseau, and J. C. Brosse. "Polymérisation de monomères organiques dans les plasmas froids—4." European Polymer Journal 21, no. 1 (1985): 1–7. http://dx.doi.org/10.1016/0014-3057(85)90056-4.

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12

-Perrin, Jérôme. "Les applications des plasmas froids dans l'industrie de l'électronique." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 95. http://dx.doi.org/10.3845/ree.1998.045.

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13

-Remy, Michel. "Les applications des plasmas froids dans les secteurs des métaux, des céramiques et du verre." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 91. http://dx.doi.org/10.3845/ree.1998.044.

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14

Debarnot, Dominique, Tiphaine Mérian, Aissam Airoudj, and Fabienne Poncin-Epaillard. "Elaboration de couches de polyaniline pour capteurs optiques d’ammoniac. Les plasmas froids en tant que technique d’élaboration." Instrumentation Mesure Métrologie 11, no. 1-2 (2011): 125–47. http://dx.doi.org/10.3166/i2m.11.1-2.125-147.

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15

Epaillard, F., J. C. Brosse, and G. Legeay. "Polymérisation de monomères organiques dans des plasmas froids—V. Polymérisation de monomères acryliques en présence d'amorceurs et de coamorceurs." European Polymer Journal 23, no. 3 (1987): 233–36. http://dx.doi.org/10.1016/0014-3057(87)90080-2.

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16

-Terrat, J. P. "Les réacteurs à plasma froid technologies." Revue de l'Electricité et de l'Electronique -, no. 04 (1998): 85. http://dx.doi.org/10.3845/ree.1998.042.

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17

Handayani, Airine Hijrah, Arbi Dimyati, Abdul Waris, et al. "Rapid Synthesis of Graphene Oxide Derived from Biomass with Atmospheric Plasma Technology." Journal of Mathematical and Fundamental Sciences 56, no. 1 (2024): 68–84. http://dx.doi.org/10.5614/j.math.fund.sci.2024.56.1.5.

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In this study, we explored a low-cost, green, and renewable approach utilizing biomass resources, i.e., coconut fronds, palm fronds, and rambutan stems, to rapidly synthesize graphene oxide via atmospheric plasma techniques. The plasma treatment, with argon gas as the plasma source and a power source of 960 W, lasted for 5 minutes. Graphene oxide (GO) was confirmed using SEM and TEM images with a C:O content ratio greater than 80% for all samples and the formation of graphene layers. The presence of a D-band and a G-band in Raman spectroscopy as well as O-H and C-O groups in the FTIR confirmed the existence of GO.

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18

Duval, A., I. Marinov, S. M. Starikovskaia, A. Rousseau, and A. Janin. "Étude préclinique sur les applications cutanées des plasmas physiques : effets cellulaires et tissulaires d’un plasma froid nanoseconde." Annales de Dermatologie et de Vénéréologie 140, no. 12 (2013): S500—S501. http://dx.doi.org/10.1016/j.annder.2013.09.316.

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19

Purawiardi, R. I., A. Dimyati, A. H. Handayani, et al. "Plasma-assisted pyrolysis for converting oil palm fronds into reduced graphite oxide." IOP Conference Series: Earth and Environmental Science 1309, no. 1 (2024): 012001. http://dx.doi.org/10.1088/1755-1315/1309/1/012001.

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Abstract One of the oil palm tree’s solid waste is oil palm fronds. Due to its lignocellulosic composition, it has the potency to convert it into carbon. The common heat treatment method to convert oil palm fronds into carbon-based material is pyrolysis. However, this process has some disadvantages, such as being time-consuming and just producing amorphous carbon. Different from common pyrolysis temperatures, in this study we use a higher temperature (4000 °C) generated by DC current arc plasma. This process is faster than the common pyrolysis process (less than 10 minutes) and produces crystalline material. This product is then characterized by Raman spectroscopy, SAED-TEM, XRD, FT-IR, and SEM/EDX. Based on Raman spectroscopy, this crystalline material shows the characteristics of semiconductor carbon. Based on the SAED-TEM, there is a (002) plane of hexagonal crystal structure detected (graphite phase characteristics). An XRD analysis shows the characteristics of the trigonal crystal structure (P3) constructed by O and H atoms. An FT-IR characterization shows that there are C=C, C-H, and O-H bonds, while the EDX analysis result shows a carbon-to-oxygen ratio of about 4.23. Therefore, based on the whole interpretation, the plasma-assisted pyrolysis treatment is successfully used to convert oil palm fronds into reduced graphite oxide (rGO).

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20

Benoist, Pascale, and Gilbert Legeay. "Traitement de surface d'un polyurethane par plasma froid: fixation de fluor." European Polymer Journal 30, no. 11 (1994): 1283–87. http://dx.doi.org/10.1016/0014-3057(94)90139-2.

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21

Poncin-Epaillard, Fabienne, and Jean-Claude Brosse. "Quelques avantages de la polymérisation induite par un plasma froid microonde." Die Makromolekulare Chemie 191, no. 3 (1990): 691–99. http://dx.doi.org/10.1002/macp.1990.021910324.

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22

Benoist, P., G. Legeay, R. Morello, and F. Poncin-Epaillard. "Preparation de surfaces de polymeres par plasma froid pour metallisation par galvanochimie." European Polymer Journal 28, no. 11 (1992): 1383–93. http://dx.doi.org/10.1016/0014-3057(92)90280-f.

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23

Lauque, P., H. Carchano, and C. Jacolin. "Polymérisation par plasma froid d'un revêtement sur la surface interne de cathéters." European Polymer Journal 32, no. 6 (1996): 725–33. http://dx.doi.org/10.1016/0014-3057(95)00209-x.

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24

Garrigues, Laurent, Freddy Gaboriau, Alexandre Guglielmi, and Jean-Pierre Boeuf. "Missions du futur et nouveaux concepts en propulsion plasma." Reflets de la physique, no. 70 (October 2021): 24–30. http://dx.doi.org/10.1051/refdp/202170024.

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L’intérêt d’utiliser des particules chargées accélérées à de grandes vitesses pour propulser un engin spatial a germé dans la tête de C. Tsiolkovski (1857-1935), qui a posé les fondements de l’astronautique dans son ouvrage de 1903. Il a fallu néanmoins attendre la course à l’espace durant la guerre froide pour voir émerger les premiers concepts de propulseurs à plasma, puis leur utilisation sur les satellites et les premières sondes d’exploration à la fin du XXe siècle. Le XXIe siècle ouvre la voie à de nouveaux concepts pour des plateformes de satellites toujours plus massives, des sondes d’exploration envoyées toujours plus loin, ou des vols habités pour l’exploration de la planète Mars.

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25

Chasset, René, Gilbert Legeay, Jean-Charles Touraine, and Bernard Arzur. "Fluoration du polyéthylène par plasma froid: mouillabilité, indice limite d'oxygène, coefficient de frottement." European Polymer Journal 24, no. 11 (1988): 1049–55. http://dx.doi.org/10.1016/0014-3057(88)90064-x.

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26

Kazadi, M. B., and L. B. Lofo. "Sur la Propagation d’ondes Electromagnétiques dans un Plasma Froid dans un Champ Electromagnétique en Rotation." Physica Scripta 58, no. 5 (1998): 496–98. http://dx.doi.org/10.1088/0031-8949/58/5/012.

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27

Ben Taleb, A., O. Dessaux, D. Djebabra, and P. Goudmand. "Formation d'etats triplets du biacetyle dans sa reaction en phase gazeuse avec un plasma froid d'azote." Journal of Photochemistry and Photobiology A: Chemistry 40, no. 2-3 (1987): 233–43. http://dx.doi.org/10.1016/1010-6030(87)85003-7.

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BADIE, J. M., B. GRANIER, and B. BONDUELLE. "CARACTÉRISATION DES FLUX ÉCHANGÉS ENTRE UN ÉCOULEMENT DE PLASMA D'ARGON DANS L'AIR ET UNE CIBLE PLANE FROIDE." Le Journal de Physique Colloques 51, no. C5 (1990): C5–273—C5–279. http://dx.doi.org/10.1051/jphyscol:1990533.

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29

Gomes de Lima, P., J. Lopez, B. Despax, and C. Mayoux. "Sur l'efficacité des ions et des électrons dans un plasma froid venant en contact avec un polymère." Revue de Physique Appliquée 24, no. 3 (1989): 331–35. http://dx.doi.org/10.1051/rphysap:01989002403033100.

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30

Ben Taleb, A., O. Dessaux, and P. Goudmand. "Etudes spectroscopiques comparees des interactions d'un plasma froid differe d'azote avec le formaldehyde, le glyoxal et le biacetyle." Journal of Photochemistry and Photobiology A: Chemistry 46, no. 1 (1989): 1–14. http://dx.doi.org/10.1016/1010-6030(89)87028-5.

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31

Liu, Xuqiang, Jing Dong, Qiongxin Liang, et al. "Coagulant Effects and Mechanism of Schefflera heptaphylla (L.) Frodin." Molecules 24, no. 24 (2019): 4547. http://dx.doi.org/10.3390/molecules24244547.

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Schefflera heptaphylla (L.) Frodin, are commonly used in anti-inflammatory, analgesic, traumatic bleeding and hemostasisas. In this paper, the coagulation effect of the ethanol extract (Set), ethyl acetate phase (Sea) and n-butanol phase (Sbu) was evaluated by prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT) and fibrinogen content (FIB) assays in vitro. Then, Three main lupanine triterpenes (compounds A–C) were isolated and identified from Sea and Sbu by a bioassay-guided method and their structure were identified as 3α-Hydroxy-lup-20(29)-ene-23, 28-dioic acid, betulinic acid 3-O-sulfate and 3α-Hydroxy-lup-20(29)-ene-23, 28-dioic acid 28-O-(α-l-rhamnopyranosyl(1→4)-O-β-d-glucopyranosyl(1→6))-β-d-glucopyranoside) by spectroscopic data analysis. Among of them, compound B was confirmed to have significant coagulant effect in vitro. Furthermore, the pro-coagulation mechanism of S. heptaphylla extracts and compound B were investigated by measuring whole blood viscosity (WBV), plasma viscosity (PV), erythrocyte sedimentetion rate (ESR), pack cell volume (PCV), APTT, PT, TT, and FIB in vivo. Meanwhile, the levels of thromboxane B2 (TXB2), 6-keto prostaglandin F1α (6-keto-PGF1α), endothelial nitric oxide synthase (eNOS) and (endothelin-1) ET-1 were detected. The bleeding time (BT) was tested by tail bleeding method, which proved the traumatic bleeding and hemostasis activities of S. heptaphylla. The pharmacology experiments showed that the Set, Sea, Sbu and compound B has significant pro-coagulation effect. In addition, compound B might be the main constituent of pro-coagulation in S. heptaphylla These results could support the fact that S. heptaphylla could be used traditionally to cure traumatic bleeding, and the pro-coagulation effects were associated with the regulation of vascular endothelium active substance and hemorheology parameters.

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G., V. "Pathological and anatomical basis of inflammation (Zeitschr. F. Pathologie, 1920, Bd. 24)." Kazan medical journal 18, no. 1 (2021): 149–50. http://dx.doi.org/10.17816/kazmj79650.

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With his classical experiments on the frog's mesentery, Conheim established, as is known, that inflammation is based on the emigration of leukocytes per diapedesin through the vascular wall, and Conheim relates to this emigration the marks that appear in the tissues undergoing inflammation. Subsequently, Marchand, Herzog and others made a significant amendment to the teachings of Conheim'a - that, in addition to emigrated leukocytes, the cells of the inflammatory infiltrate located around the vessels also have a histogenic origin, being the results of the proliferation of especially adventitiae elements, and those found in infiltration of polynuclear cells, not to mention lymphocytes, mast and plasma cells.

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Gouanvé, Fabrice, Stéphane Marais, Michel Métayer, Claudine Morvan, and Fabienne Poncin-Epaillard. "Composites polyester insaturé renforcés par des fibres de lin. Effets de traitements plasma froid et autoclave sur les propriétés perméamétriques." Revue des composites et des matériaux avancés 16, no. 1 (2006): 115–28. http://dx.doi.org/10.3166/rcma.16.115-128.

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34

Tokmakov, Alexander A., Ryuga Teranishi, and Ken-Ichi Sato. "Spontaneous Overactivation of Xenopus Frog Eggs Triggers Necrotic Cell Death." International Journal of Molecular Sciences 25, no. 10 (2024): 5321. http://dx.doi.org/10.3390/ijms25105321.

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The excessive activation of frog eggs, referred to as overactivation, can be initiated by strong oxidative stress, leading to expedited calcium-dependent non-apoptotic cell death. Overactivation also occurs spontaneously, albeit at a low frequency, in natural populations of spawned frog eggs. Currently, the cytological and biochemical events of the spontaneous process have not been characterized. In the present study, we demonstrate that the spontaneous overactivation of Xenopus frog eggs, similarly to oxidative stress- and mechanical stress-induced overactivation, is characterized by the fast and irreversible contraction of the egg’s cortical layer, an increase in egg size, the depletion of intracellular ATP, a drastic increase in the intracellular ADP/ATP ratio, and the degradation of M phase-specific cyclin B2. These events manifest in eggs in the absence of caspase activation within one hour of triggering overactivation. Importantly, substantial amounts of ATP and ADP leak from the overactivated eggs, indicating that plasma membrane integrity is compromised in these cells. The rupture of the plasma membrane and acute depletion of intracellular ATP explicitly define necrotic cell death. Finally, we report that egg overactivation can occur in the frog’s genital tract. Our data suggest that mechanical stress may be a key factor promoting egg overactivation during oviposition in frogs.

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35

Capobianco, Giuseppe, Giuseppe Bonifazi, Silvia Serranti, et al. "A Green Approach Based on Micro-X-ray Fluorescence for Arsenic, Micro- and Macronutrients Detection in Pteris vittata." Water 14, no. 14 (2022): 2202. http://dx.doi.org/10.3390/w14142202.

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In this study, benchtop micro-X-ray fluorescence spectrometry (µXRF) was evaluated as a green and cost-effective multielemental analytical technique for P. vittata. Here, we compare the arsenic (As) content values obtained from the same samples by µXRF and inductively coupled plasma-optical emissions spectrometry (ICP–OES). To obtain samples with different As concentrations, fronds at different growth time points were collected from P. vittata plants grown on two natural As-rich soils with either high or moderate As (750 and 58 mg/kg). Dried samples were evaluated using multielement-µXRF analysis and processed by PCA. The same samples were then analysed for multielement concentrations by ICP–OES. We show that As concentrations detected by ICP–OES, ranging from 0 to 3300 mg/kg, were comparable to those obtained by µXRF. Similar reliability was obtained for micro- and macronutrient concentrations. A positive correlation between As and potassium (K) contents and a negative correlation between As and iron (Fe), calcium (Ca) and manganese (Mn) contents were found at both high and moderate As. In conclusion, we demonstrate that this methodological approach based on μXRF analysis is suitable for monitoring the As and element contents in dried plant tissues without any chemical treatment of samples and that changes in most nutrient concentrations can be strictly related to the As content in plant tissue.

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Basanta, David, Ryan Bishop, Anna Miller, et al. "Abstract B019: The bone microenvironment's impact on the heterogeneity of resistance to proteasome inhibitors in multiple myeloma." Cancer Research 84, no. 3_Supplement_2 (2024): B019. http://dx.doi.org/10.1158/1538-7445.canevol23-b019.

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Abstract Multiple myeloma (MM) is an osteolytic plasma cell malignancy that, despite being responsive to therapies such as proteasome inhibitors, frequently relapses. Understanding the mechanism and the niches where resistant disease evolves remains of major clinical importance. Cancer cell intrinsic mechanisms and bone ecosystem factors are known contributors to the evolution of resistant MM but the exact contribution of each is difficult to define with current in vitro and in vivo models. Using a novel bmathematical model that incorporates key cellular species of the bone ecosystem that control normal bone remodeling and, in MM, yields a protective environment we studied how, under therapy, the bone ecosystem contributes to the evolutionary dynamics of resistant MM under control and proteasome inhibitor treatment. Our results show that Environmentally-Mediated Drug Resistance (EMDR) might not be sufficient to explain resistant disease. But our results highlight the importance of EMDR in facilitating the emergence of resistance, and more importantly facilitating the survival of tolerant cells, allowing the tumor multiple routes for resistant disease. Our results also provide evidence that intervention with therapies targetting the bone ecosystem would significantly improve the ability of treatment to increase the time to progression for patients with multiple myeloma and, potentially, other diseases where EMDR plays a role. Citation Format: David Basanta, Ryan Bishop, Anna Miller, Conor C. Lynch, Matthew Froid, Ariosto S. Silva, Kenneth H. Shain. The bone microenvironment's impact on the heterogeneity of resistance to proteasome inhibitors in multiple myeloma [abstract]. In: Proceedings of the AACR Special Conference in Cancer Research: Translating Cancer Evolution and Data Science: The Next Frontier; 2023 Dec 3-6; Boston, Massachusetts. Philadelphia (PA): AACR; Cancer Res 2024;84(3 Suppl_2):Abstract nr B019.

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POINTU, Anne-Marie, Jérôme PERRIN, and Jacques JOLLY. "Plasmas froids de décharge - Propriétés électriques." Conversion de l'énergie électrique, February 1998. http://dx.doi.org/10.51257/a-v1-d2830.

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POINTU, Anne-Marie, Jérôme PERRIN, and Jacques JOLLY. "Plasmas froids de décharge - Applications et diagnostic." Conversion de l'énergie électrique, November 1997. http://dx.doi.org/10.51257/a-v1-d2835.

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39

Antenozio, M. L., G. Giannelli, R. Marabottini, et al. "Phytoextraction efficiency of Pteris vittata grown on a naturally As-rich soil and characterization of As-resistant rhizosphere bacteria." Scientific Reports 11, no. 1 (2021). http://dx.doi.org/10.1038/s41598-021-86076-7.

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AbstractThis study evaluated the phytoextraction capacity of the fern Pteris vittata grown on a natural arsenic-rich soil of volcanic-origin from the Viterbo area in central Italy. This calcareous soil is characterized by an average arsenic concentration of 750 mg kg−1, of which 28% is bioavailable. By means of micro-energy dispersive X-ray fluorescence spectrometry (μ-XRF) we detected As in P. vittata fronds after just 10 days of growth, while a high As concentrations in fronds (5,000 mg kg−1), determined by Inductively coupled plasma-optical emission spectrometry (ICP-OES), was reached after 5.5 months. Sixteen arsenate-tolerant bacterial strains were isolated from the P. vittata rhizosphere, a majority of which belong to the Bacillus genus, and of this majority only two have been previously associated with As. Six bacterial isolates were highly As-resistant (> 100 mM) two of which, homologous to Paenarthrobacter ureafaciens and Beijerinckia fluminensis, produced a high amount of IAA and siderophores and have never been isolated from P. vittata roots. Furthermore, five isolates contained the arsenate reductase gene (arsC). We conclude that P. vittata can efficiently phytoextract As when grown on this natural As-rich soil and a consortium of bacteria, largely different from that usually found in As-polluted soils, has been found in P. vittata rhizosphere.

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40

Gongwala, J., A. Paltahe, G. Payom, and D. Njopwouo. "Analyse et traitement par plasma froid des eaux de rejet de « l’abattoir des Brasseries » à Yaoundé." International Journal of Biological and Chemical Sciences 6, no. 6 (2013). http://dx.doi.org/10.4314/ijbcs.v6i6.41.

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41

Martín-Cófreces, Noa Beatriz, José María Valpuesta, and Francisco Sánchez-Madrid. "Folding for the Immune Synapse: CCT Chaperonin and the Cytoskeleton." Frontiers in Cell and Developmental Biology 9 (April 12, 2021). http://dx.doi.org/10.3389/fcell.2021.658460.

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Lymphocytes rearrange their shape, membrane receptors and organelles during cognate contacts with antigen-presenting cells (APCs). Activation of T cells by APCs through pMHC-TCR/CD3 interaction (peptide-major histocompatibility complex-T cell receptor/CD3 complexes) involves different steps that lead to the reorganization of the cytoskeleton and organelles and, eventually, activation of nuclear factors allowing transcription and ultimately, replication and cell division. Both the positioning of the lymphocyte centrosome in close proximity to the APC and the nucleation of a dense microtubule network beneath the plasma membrane from the centrosome support the T cell’s intracellular polarity. Signaling from the TCR is facilitated by this traffic, which constitutes an important pathway for regulation of T cell activation. The coordinated enrichment upon T cell stimulation of the chaperonin CCT (chaperonin-containing tailless complex polypeptide 1; also termed TRiC) and tubulins at the centrosome area support polarized tubulin polymerization and T cell activation. The proteasome is also enriched in the centrosome of activated T cells, providing a mechanism to balance local protein synthesis and degradation. CCT assists the folding of proteins coming fromde novosynthesis, therefore favoring mRNA translation. The functional role of this chaperonin in regulating cytoskeletal composition and dynamics at the immune synapse is discussed.

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Sravani, T., та K. Sunitha. "Phytochemical Screening and α-Glucosidase Inhibitor Activity of Aerial Parts of Maidenhair Fern: <i>Adiantum lunulatum</i>". Journal of Natural Remedies, 30 червня 2024, 1355–62. http://dx.doi.org/10.18311/jnr/2024/35850.

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Background: Medicinal plants and herbs are used extensively in traditional medicine to treat and manage a wide range of conditions, including diabetes mellitus and its after-effects. As diabetes mellitus is increasing rapidly and is mostly caused by changes in lifestyle, the use of traditional medicines for its treatment and management has increased. Fern extracts have demonstrated tremendous potential in the management of diabetes, cancer, cardiovascular problems and neurological disorders. A prominent class of type 2 antidiabetic drugs and α-glucosidase inhibitors work by lowering postprandial hyperglycemia. Aim: The purpose of this in vitro investigation was to assess any possible inhibitory effects of aerial portions of the Maidenhair Fern (Adiantum lunulatum Burm). Methods: Using extracts of Adiantum lunulatum derived from methanolic and chloroform solvents, the research team performed phytochemical screenings to ascertain if the extracts could stop α-glucosidase. Results: Minimising the postprandial plasma glucose spikes is achieved by delaying the absorption of carbs and glucose by inhibiting the activity of α-glucosidase. The chloroform extract of Adiantum lunulatum exhibited an IC50 value of 705.02 ± 2.122 μg/ml and the methanol extract exhibited an IC50 value of 526.12 ± 1.155 μg/ml. Acarbose was used as a positive control with an IC50 value of 314.11 ± 1.021 μg/ml. The methanol extract exhibited more potent alpha-glucosidase inhibitory activity than other extracts. The phytochemical screening of the extracts showed the presence of polyphenols and flavonoids. The microscopic study of the rachis of the fronds was carried out which showed the presence of a single layer of epidermic, sclerenchyma, stele and exarch xylem which helps in authentication. Conclusion: These findings can pave the way for the development of novel medicinal compounds derived from the Maidenhair Fern and bring more standardisation to the use of traditional herbal therapies for the treatment of diabetes mellitus.

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Journal articles on the topic 'Plasmas froids'

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