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1

Martínez-Martínez, Luis, María Eliecer Cano, José Manuel Rodríguez-Martínez, Jorge Calvo, and Álvaro Pascual. "Plasmid-mediated quinolone resistance." Expert Review of Anti-infective Therapy 6, no. 5 (2008): 685–711. http://dx.doi.org/10.1586/14787210.6.5.685.

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2

DRABU, Y. J., P. H. BLAKEMORE, D. M. COX, and A. McLAREN. "Plasmid-mediated ceftazidime resistance." Journal of Antimicrobial Chemotherapy 23, no. 2 (1989): 287–90. http://dx.doi.org/10.1093/jac/23.2.287.

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3

PHILLIPS, IAN, ANNA KING, and KEVIN SHANNON. "Plasmid-mediated ceftazidime resistance." Journal of Antimicrobial Chemotherapy 24, no. 1 (1989): 85. http://dx.doi.org/10.1093/jac/24.1.85.

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4

Schultsz, Constance, and Suzanne Geerlings. "Plasmid-Mediated Resistance in Enterobacteriaceae." Drugs 72, no. 1 (2012): 1–16. http://dx.doi.org/10.2165/11597960-000000000-00000.

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5

Piekarska, Katarzyna. "PLASMID-MEDIATED QUINOLONE RESISTANCE - PMQR." Postępy Mikrobiologii - Advancements of Microbiology 57, no. 1 (2019): 47–57. http://dx.doi.org/10.21307/pm-2018.57.1.047.

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6

Starliper, Clifford E., Richard K. Cooper, Emmett B. Shotts, and Peter W. Taylor. "Plasmid-Mediated Romet Resistance ofEdwardsiella ictaluri." Journal of Aquatic Animal Health 5, no. 1 (1993): 1–8. http://dx.doi.org/10.1577/1548-8667(1993)005<0001:pmrroe>2.3.co;2.

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7

Rodriguez-Martinez, Jose-Manuel, Laurent Poirel, Alvaro Pascual, and Patrice Nordmann. "Plasmid-Mediated Quinolone Resistance in Australia." Microbial Drug Resistance 12, no. 2 (2006): 99–102. http://dx.doi.org/10.1089/mdr.2006.12.99.

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8

Tran, J. H., and G. A. Jacoby. "Mechanism of plasmid-mediated quinolone resistance." Proceedings of the National Academy of Sciences 99, no. 8 (2002): 5638–42. http://dx.doi.org/10.1073/pnas.082092899.

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9

Jacoby, George A., Nancy Chow, and Ken B. Waites. "Prevalence of Plasmid-Mediated Quinolone Resistance." Antimicrobial Agents and Chemotherapy 47, no. 2 (2003): 559–62. http://dx.doi.org/10.1128/aac.47.2.559-562.2003.

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ABSTRACT Quinolone resistance encoded by the qnr gene and mediated by plasmid pMG252 was discovered in a clinical strain of Klebsiella pneumoniae that was isolated in 1994 at the University of Alabama at Birmingham Medical Center. The gene codes for a protein that protects DNA gyrase from quinolone inhibition and that belongs to the pentapeptide repeat family of proteins. The prevalence of the gene has been investigated by using PCR with qnr-specific primers with a sample of more than 350 gram-negative strains that originated in 18 countries and 24 states in the United States and that included
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10

Dolejska, Monika, and Costas C. Papagiannitsis. "Plasmid-mediated resistance is going wild." Plasmid 99 (September 2018): 99–111. http://dx.doi.org/10.1016/j.plasmid.2018.09.010.

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11

Rodríguez-Martínez, José Manuel, Carmen Velasco, Álvaro Pascual, et al. "Plasmid-mediated quinolone resistance: an update." Journal of Infection and Chemotherapy 17, no. 2 (2011): 149–82. http://dx.doi.org/10.1007/s10156-010-0120-2.

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12

Molnár, Annamária, Gabriella Spengler, and Yvette Mándi. "Infectious Plasmid Resistance and Efflux Pump Mediated Resistance." Acta Microbiologica et Immunologica Hungarica 51, no. 3 (2004): 333–49. http://dx.doi.org/10.1556/amicr.51.2004.3.11.

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13

Chub, О. І., O. V. Bilchenko, and S. V. Teslenko. "BACTERIAL SUSCEPTIBILITY-RESISTANCE LEVELS OF CHRONIC PYELONEPHRITIS PATHOGENS’, DEPENDING ON EXPRESSION OF DIFFERENT TYPES OF PLASMID-MEDIATED RESISTANCE GENES." Ukrainian Journal of Nephrology and Dialysis, no. 2(54) (June 1, 2017): 33–39. http://dx.doi.org/10.31450/ukrjnd.2(54).2017.07.

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The aim of the study is to determine the bacterial susceptibility-resistance levels of uropathogens depending on expression of different types of plasmid-mediated resistance genes.&#x0D; Methods. A cross-sectional study of105 patients with chronic pyelonephritis was carried. Screening for the presence of plasmid-mediated genes was performed by polymerase chain reaction. The antimicrobial susceptibility of isolates was determined by the Kirby Bauer disk diffusion method on Mueller–Hinton agar-containing plates. The size of zone around each antimicrobial disk was interpreted as sensitive, interm
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14

Velhner, Maja, Gordana Kozoderović, Zora Jelesić, Igor Stojanov, Dubravka Potkonjak, and Jelena Petrović. "PLASMID MEDIATED RESISTANCE TO QUINOLONES IN SALMONELLA." Archives of Veterinary Medicine 5, no. 1 (2012): 19–29. http://dx.doi.org/10.46784/e-avm.v5i1.158.

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Plasmid mediated resistance to quinolones in Salmonella enterica is briefly presented. World wide spread of qnr determinants is evident, indicating the necessity for prudent use of antimicrobials in human and veterinary medicine. In discovering plasmid mediated resistance to quinolones antimicrobial resistance monitoring for β-lactam antibiotics is helpful, since their target genes frequently coexist in plasmid. Nevertheless, 100% reliable method for screening of qnr determinants has not been discovered. The finding of qnr genes and other determinants from the large collection of Salmonella is
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15

Erac, Bayri, Fethiye Ferda Yilmaz, Ismail Ozturk, Sabire Sohret Aydemir, and Mine Hosgor-Limoncu. "Analyses of Plasmids Harbouring Quinolone Resistance Determinants in Enterobacteriaceae Members." Polish Journal of Microbiology 66, no. 4 (2017): 529–32. http://dx.doi.org/10.5604/01.3001.0010.7084.

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The aim of this study was to explore the plasmid characteristics of eight clinical Enterobacteriaceae strains containing extended broad spectrum beta-lactamases and plasmid-mediated quinolone resistance. Plasmids were transferred by conjugation or transformation and resistance determinants were investigated by PCR. We showed that at least one plasmid harbouring qnrB or qnrS determinant was transferred by conjugation in five isolates. QepA determinant was confirmed to be on a non-conjugative plasmid. We found at least one beta-lactamase gene in seven of the eight clinical isolates having plasmi
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16

Nordmann, P., and L. Poirel. "Plasmid-mediated colistin resistance: an additional antibiotic resistance menace." Clinical Microbiology and Infection 22, no. 5 (2016): 398–400. http://dx.doi.org/10.1016/j.cmi.2016.03.009.

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17

Alawi, Marwa, Trinidad Velasco Torrijos, and Fiona Walsh. "Plasmid-mediated antimicrobial resistance in drinking water." Environmental Advances 8 (July 2022): 100191. http://dx.doi.org/10.1016/j.envadv.2022.100191.

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18

Panigrahi, D., Abdulaziz H. Al-Aneziz, and P. W. J. West. "Plasmid-mediated multidrug resistance inSalmonella typhiin Kuwait." Tropical Medicine & International Health 1, no. 4 (1996): 439–42. http://dx.doi.org/10.1046/j.1365-3156.1996.d01-80.x.

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19

Strahilevitz, Jacob, George A. Jacoby, David C. Hooper, and Ari Robicsek. "Plasmid-Mediated Quinolone Resistance: a Multifaceted Threat." Clinical Microbiology Reviews 22, no. 4 (2009): 664–89. http://dx.doi.org/10.1128/cmr.00016-09.

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SUMMARY Although plasmid-mediated quinolone resistance (PMQR) was thought not to exist before its discovery in 1998, the past decade has seen an explosion of research characterizing this phenomenon. The best-described form of PMQR is determined by the qnr group of genes. These genes, likely originating in aquatic organisms, code for pentapeptide repeat proteins. These proteins reduce susceptibility to quinolones by protecting the complex of DNA and DNA gyrase or topoisomerase IV enzymes from the inhibitory effect of quinolones. Two additional PMQR mechanisms were recently described. aac(6′)-Ib
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20

Kehrenberg, C. "Plasmid-mediated florfenicol resistance in Pasteurella trehalosi." Journal of Antimicrobial Chemotherapy 58, no. 1 (2006): 13–17. http://dx.doi.org/10.1093/jac/dkl174.

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21

Chandrasekaran, S., and D. Lalithakumari. "Plasmid-mediated rifampicin resistance in Pseudomonas fluorescens." Journal of Medical Microbiology 47, no. 3 (1998): 197–200. http://dx.doi.org/10.1099/00222615-47-3-197.

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22

Etienne, Jérôme, Guy Gerbaud, Patrice Courvalin, and Jean Fleurette. "Plasmid-mediated resistance to fosfomycin inStaphylococcus epidermidis." FEMS Microbiology Letters 61, no. 1-2 (1989): 133–38. http://dx.doi.org/10.1111/j.1574-6968.1989.tb03566.x.

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23

Minsavage, G. V. "Plasmid-Mediated Resistance to Streptomycin inXanthomonas campestrispv.vesicatoria." Phytopathology 80, no. 8 (1990): 719. http://dx.doi.org/10.1094/phyto-80-719.

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24

Schwarz, S., M. Cardoso, and H. Blobel. "Plasmid-mediated Chloramphenicol Resistance in Staphylococcus hyicus." Microbiology 135, no. 12 (1989): 3329–36. http://dx.doi.org/10.1099/00221287-135-12-3329.

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25

Sukupolvi, Soila, Petri Riikonen, Suvi Taira, Hannu Saarilahti, and Mikael Rhen. "Plasmid-mediated serum resistance in Salmonella enterica." Microbial Pathogenesis 12, no. 3 (1992): 219–25. http://dx.doi.org/10.1016/0882-4010(92)90056-t.

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26

Facinelli, B., and P. E. Varaldo. "Plasmid-mediated sulfonamide resistance in Neisseria meningitidis." Antimicrobial Agents and Chemotherapy 31, no. 10 (1987): 1642–43. http://dx.doi.org/10.1128/aac.31.10.1642.

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27

Li, C. G. "Qnr Prevalence of Plasmid-Mediated Quionlone Resistance." International Journal of Infectious Diseases 12 (December 2008): e108. http://dx.doi.org/10.1016/j.ijid.2008.05.270.

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28

Rodríguez-Martínez, José Manuel, Jesús Machuca, María Eliecer Cano, Jorge Calvo, Luis Martínez-Martínez, and Alvaro Pascual. "Plasmid-mediated quinolone resistance: Two decades on." Drug Resistance Updates 29 (November 2016): 13–29. http://dx.doi.org/10.1016/j.drup.2016.09.001.

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29

Aruhomukama, Dickson, Ivan Sserwadda, and Gerald Mboowa. "Investigating colistin drug resistance: The role of high-throughput sequencing and bioinformatics." F1000Research 8 (February 4, 2019): 150. http://dx.doi.org/10.12688/f1000research.18081.1.

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Bacterial infections involving antibiotic resistant gram-negative bacteria continue to increase and represent a major global public health concern. Resistance to antibiotics in these bacteria is mediated by chromosomal and/or acquired resistance mechanisms, these give rise to multi-drug resistant (MDR) or extensive drug resistant (XDR) bacterial strains. Most recently, a novel acquired plasmid mediated resistance mechanism to colistin, an antibiotic that had been set apart as the last resort antibiotic in the treatment of infections involving MDR and XDR gram-negative bacteria, has been report
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30

Aruhomukama, Dickson, Ivan Sserwadda, and Gerald Mboowa. "Investigating colistin drug resistance: The role of high-throughput sequencing and bioinformatics." F1000Research 8 (May 20, 2019): 150. http://dx.doi.org/10.12688/f1000research.18081.2.

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Bacterial infections involving antibiotic-resistant gram-negative bacteria continue to increase and represent a major global public health concern. Resistance to antibiotics in these bacteria is mediated by chromosomal and/or acquired resistance mechanisms, these give rise to multi-drug resistant (MDR), extensive-drug resistant (XDR) or pan-drug resistant (PDR) bacterial strains. Most recently, plasmid-mediated resistance to colistin, an antibiotic that had been set apart as the last resort antibiotic in the treatment of infections involving MDR, XDR and PDR gram-negative bacteria has been rep
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31

Chub, О., and O. Bilchenko. "PLASMID-INDUCED ANTIBIOTIC RESISTANCE AMONG PATHOGENS OF CHRONIC PYELONEPHRITIS: PREVALENCE OF GENES AND MAJOR RISK FACTORS." Ukrainian Journal of Nephrology and Dialysis, no. 2(50) (June 3, 2016): 52–55. http://dx.doi.org/10.31450/ukrjnd.2(50).2016.04.

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The aim of the study is to determine the prevalence of plasmid-mediated resistance genes among uro- pathogens from hospitalized patients with chronic pyelonephritis.&#x0D; Methods. A cross-sectional study of 105patients with chronic pyelonephritis and different stage of chronic kidney disease, was carried. Screening for the presence ofplasmid-mediated genes was performed by polymerase chain reaction. Determining the risk factors was performed by analysis of prevalence Odd-ratio.&#x0D; Results. The prevalence of plasmid-mediated resistance mechanisms among uropathogens is 36.7%, mainly due to e
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32

Antonelli, Alberto, Marco Maria D'Andrea, Tommaso Giani, and Gian Maria Rossolini. "Plasmid-mediated or chromosomally mediated colistin resistance in Klebsiella pneumoniae ?" Lancet Infectious Diseases 17, no. 1 (2017): 26–27. http://dx.doi.org/10.1016/s1473-3099(16)30552-7.

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33

Sami, ManalMahmoud, ThankamMariam Boniface, CrystalSharon Danthi, Iqra Rafiq, Priyanka Lalwani, and MahmoodY Hachim. "Characterization of plasmid-mediated versus non-plasmid-mediated bacterial antibiotic resistance in Escherichia coli isolate." Hamdan Medical Journal 7, no. 2 (2014): 269. http://dx.doi.org/10.7707/hmj.v7i2.367.

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34

Yang, Xiaoman, Rundong Shu, Leqi Hou, et al. "mcr-1-Mediated In Vitro Inhibition of Plasmid Transfer Is Reversed by the Intestinal Environment." Antibiotics 11, no. 7 (2022): 875. http://dx.doi.org/10.3390/antibiotics11070875.

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Colistin is regarded as an antibiotic of last resort against multidrug-resistant Gram-negative bacteria, including Klebsiella pneumoniae and Escherichia coli. Colistin resistance is acquired by microorganisms via chromosome-mediated mutations or plasmid-mediated mobile colistin resistance (mcr) gene, in which the transfer of mcr is the predominant factor underlying the spread of colistin resistance. However, the factors that are responsible for the spread of the mcr gene are still unclear. In this study, we observed that mcr-1 inhibited the transfer of the pHNSHP45 backbone in liquid mating. S
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35

Dalmolin, Tanise, Daiana Lima-Morales, and Afonso Barth. "Plasmid-mediated Colistin Resistance: What Do We Know?" Journal of Infectiology 1, no. 2 (2018): 16–22. http://dx.doi.org/10.29245/2689-9981/2018/2.1109.

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36

Becker, Karsten, Sarah van Alen, Evgeny A. Idelevich, et al. "Plasmid-Encoded TransferablemecB-Mediated Methicillin Resistance inStaphylococcus aureus." Emerging Infectious Diseases 24, no. 2 (2018): 242–48. http://dx.doi.org/10.3201/eid2402.171074.

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37

LEMAÎTRE, JEAN-PAUL, H. ECHCHANNAOUI, G. MICHAUT, C. DIVIES, and A. ROUSSET. "Plasmid-Mediated Resistance to Antimicrobial Agents among Listeriae." Journal of Food Protection 61, no. 11 (1998): 1459–64. http://dx.doi.org/10.4315/0362-028x-61.11.1459.

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The resistance to 14 antiseptic-disinfectant and dye compounds of 208 strains of Listeria (132 L. monocytogenes, 63 L. innocua, 8 L. seeligeri, 1 L. ivanovii, 1 L. welshimeri, and 3 Listeria spp.) was tested by the agar-dilution procedure. The Listeria strains were isolated from different varieties of foods, environments of cheese dairies, humans, and wildbirds. A total of 14 (6.7%) Listeria strains (12 L. monocytogenes and 2 L. innocua) were resistant to benzalkonium chloride, hexamidine diisethionate, and ethidium bromide. This multiple resistance was observed more frequently from strains of
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38

Hopkins, Katie L., Martin Day, and E. John Threlfall. "Plasmid-mediated Quinolone Resistance inSalmonella enterica, United Kingdom." Emerging Infectious Diseases 14, no. 2 (2008): 340–42. http://dx.doi.org/10.3201/eid1402.070573.

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39

Jacoby, George A., Nancy Gacharna, Todd A. Black, George H. Miller, and David C. Hooper. "Temporal Appearance of Plasmid-Mediated Quinolone Resistance Genes." Antimicrobial Agents and Chemotherapy 53, no. 4 (2009): 1665–66. http://dx.doi.org/10.1128/aac.01447-08.

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ABSTRACT One hundred fifty AAC(6′)-Ib-positive gram-negative isolates collected between 1981 and 1991 were examined by PCR for the presence of the aac(6′)-Ib-cr variant and other plasmid-mediated quinolone resistance (PMQR) genes. None had the aac(6′)-Ib-cr variant, qnrA, qnrS, qnrC, or qepA, but two strains collected in 1988 had qnrB alleles, making these the earliest known PMQR genes.
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40

Geis, A., T. Janzen, M. Teuber, and F. Wirsching. "Mechanism of plasmid-mediated bacteriophage resistance in lactococci." FEMS Microbiology Letters 94, no. 1-2 (1992): 7–13. http://dx.doi.org/10.1111/j.1574-6968.1992.tb05279.x.

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41

DUNCAN, R., J. CAMAKARIS, B. T. O. LEE, and R. K. J. LUKE. "Inducible Plasmid-mediated Copper Resistance in Escherichia coli." Microbiology 131, no. 4 (1985): 939–43. http://dx.doi.org/10.1099/00221287-131-4-939.

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42

Robicsek, Ari, George A. Jacoby, and David C. Hooper. "The worldwide emergence of plasmid-mediated quinolone resistance." Lancet Infectious Diseases 6, no. 10 (2006): 629–40. http://dx.doi.org/10.1016/s1473-3099(06)70599-0.

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43

Poirel, Laurent, Jose-Manuel Rodriguez-Martinez, Hedi Mammeri, Alain Liard, and Patrice Nordmann. "Origin of Plasmid-Mediated Quinolone Resistance Determinant QnrA." Antimicrobial Agents and Chemotherapy 49, no. 8 (2005): 3523–25. http://dx.doi.org/10.1128/aac.49.8.3523-3525.2005.

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ABSTRACT Plasmid-mediated resistance to quinolones is increasingly reported in studies of Enterobacteriaceae. Using a PCR-based strategy, a series of gram-negative species were screened for qnrA-like genes. Shewanella algae, an environmental species from marine and fresh water, was identified as its reservoir. This is a one of the very few examples of progenitor identification of an acquired antibiotic resistance gene.
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44

Jacoby, George A., Kelley E. Walsh, Debra M. Mills, et al. "qnrB, Another Plasmid-Mediated Gene for Quinolone Resistance." Antimicrobial Agents and Chemotherapy 50, no. 4 (2006): 1178–82. http://dx.doi.org/10.1128/aac.50.4.1178-1182.2006.

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ABSTRACT A novel plasmid-mediated quinolone resistance gene, qnrB, has been discovered in a plasmid encoding the CTX-M-15 β-lactamase from a Klebsiella pneumoniae strain isolated in South India. It has less than 40% amino acid identity with the original qnr (now qnrA) gene or with the recently described qnrS but, like them, codes for a protein belonging to the pentapeptide repeat family. Strains with qnrB demonstrated low-level resistance to all quinolones tested. The gene has been cloned in an expression vector attaching a polyhistidine tag, which facilitated purification to ≥95% homogeneity.
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45

Omidvar Panah, M., M. Najafi, and A. Peymani. "Plasmid-mediated quinolones resistance in clinically important bacteria." Journal of Qazvin University of Medical Sciences 22, no. 2 (2018): 90–99. http://dx.doi.org/10.29252/qums.22.2.90.

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46

Lian, C. J., W. S. Hwang, and C. H. Pai. "Plasmid-mediated resistance to phagocytosis in Yersinia enterocolitica." Infection and Immunity 55, no. 5 (1987): 1176–83. http://dx.doi.org/10.1128/iai.55.5.1176-1183.1987.

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47

Chugh, T. D., A. Suheir, A. G. Mahboob, L. Neil, and E. El-Bishbishi. "Plasmid-mediated drug resistance of shigellae in Kuwait." Antonie van Leeuwenhoek 51, no. 2 (1985): 241–47. http://dx.doi.org/10.1007/bf02310016.

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48

Walter, Emily G., and Diane E. Taylor. "Plasmid-mediated resistance to tellurite: Expressed and cryptic." Plasmid 27, no. 1 (1992): 52–64. http://dx.doi.org/10.1016/0147-619x(92)90006-v.

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49

Rani, D. B. Rajini, and A. Mahadevan. "Plasmid mediated metal and antibiotic resistance in marinePseudomonas." Biometals 5, no. 2 (1992): 73–80. http://dx.doi.org/10.1007/bf01062217.

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50

POYARTSALMERON, C. "Transferable plasmid-mediated antibiotic resistance in Listeria monocytogenes." Lancet 335, no. 8703 (1990): 1422–26. http://dx.doi.org/10.1016/0140-6736(90)91447-i.

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