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Relevant bibliographies by topics / Platelet dynamics / Dissertations / Theses

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Dissertations / Theses on the topic 'Platelet dynamics'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Wong, Truman. "Dynamics of platelet shape change and aggregation size-dependent platelet subpopulations." Thesis, McGill University, 1988. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=61778.

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2

Lane, I. F. "The relationship between platelet-vessel wall interaction thrombosis and atherosclerosis." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233551.

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3

Kasirer-Friede, Ana. "Dynamics of von Willebrand factor-mediated platelet aggregation in laminar flow : physical and molecular determinants." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0020/NQ55344.pdf.

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4

Bark, David Lawrence Jr. "Mechanistic numerical study of trhombus growth." Thesis, Atlanta, Ga. : Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/22550.

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5

Sandmann, Rabea [Verfasser], Sarah [Akademischer Betreuer] Köster, and Florian [Akademischer Betreuer] Rehfeldt. "Blood Platelet Behavior on Structured Substrates : From Spreading Dynamics to Cell Morphology / Rabea Sandmann. Betreuer: Sarah Köster. Gutachter: Sarah Köster ; Florian Rehfeldt." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2015. http://d-nb.info/1078420084/34.

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6

Andersen, Brandon Thomas. "Multi-Processor Computation of Thrombus Growth and Embolization in a Model of Blood-Biomaterial Interaction Based on Fluid Dynamics." BYU ScholarsArchive, 2012. https://scholarsarchive.byu.edu/etd/3465.

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This work describes the development and testing of a real-time three-dimensional computational fluid dynamics simulation of thrombosis and embolization to be used in the design of blood-contacting devices. Features of the model include the adhesion and aggregation of blood platelets on device material surfaces, shear and chemical activation of blood platelets, and embolization of platelet aggregates due to shear forces. As thrombus develops, blood is diverted from its regular flow field. If shear forces on a thrombus are sufficient to overcome the strength of adhesion, the thrombus is dislodge

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7

Fiusco, Francesco. "Hemodynamics of artificial devices used in extracorporeal life support." Licentiate thesis, KTH, Teknisk mekanik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-301039.

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Extracorporeal Membrane Oxygenation (ECMO) is a life-saving therapy usedfor support in critical heart and/or lung failure. Patient’s blood is pumped viaan artiﬁcial lung for oxygenation outside of the body. The circuit is composedof a blood pump, cannulae for drainage and reinfusion, a membrane lung,tubing and connectors. Its use is associated with thromboembolic complicationsand hemolytic damage. Detailed numerical studies of two blood pumps anda lighthouse tip drainage cannula were undertaken to characterize the ﬂowstructures in diﬀerent scenarios and their link to platelet activation. The p

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8

Hosseinzadegan, Hamid. "A Physio-chemical Predictive Model of Dynamic Thrombus Formation and Growth in Stenosed Vessels." Diss., Virginia Tech, 2017. http://hdl.handle.net/10919/89325.

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According to the World Health Organization (WHO), Cardiovascular Disease (CVD) is the leading cause of death in the world. Biomechanics and fluid dynamics of blood flow play an important role in CVD mediation. Shear stress plays a major role in platelet-substrate interactions and thrombus formation and growth in blood flow, where under both pathological and physiological conditions platelet adhesion and accumulation occur. In this study, a three-dimensional dynamic model of platelet-rich thrombus growth in stenosed vessels using computational fluid dynamics (CFD) methods is introduced. Platele

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9

Cosemans, Judith Maria Elisabeth Mathijs. "Dynamic regulation of thrombus stability focus on platelet receptors and downstream signaling /." Maastricht : Maastricht : Univeritaire Pers ; University Library, Universiteit Maastricht [host], 2009. http://arno.unimaas.nl/show.cgi?fid=14676.

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10

Naeem, Ali. "Optical properties and exciton dynamics of colloidal quantum dots, rods, and platelets." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/90269/.

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The linear optical properties and exciton dynamics of different semiconductor nanostructures have been studied. A model to describe the absoprtion spectra of cadmium selenide (CdSe) nanoplatelets (NPLs) has been developed, which allows the extraction of parameters relating to excitons confined within the thickness of the NPLs. Giant oscillator strength transitions (GOST) have been observed in NPLs with a lifetime limited dephasing of the ground state excitons at low temperature of about 1 ps, using transient resonant four wave mixing in heterodyne detection. The observation of the GOST effect

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11

Pakalidou, Nikoletta. "Self-assembly of two-dimensional convex and nonconvex colloidal platelets." Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/selfassembly-of-twodimensional-convex-and-nonconvex-colloidal-platelets(072e9fad-3e34-4803-b3df-6aed3ce756c7).html.

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One of the most promising routes to create advanced materials is self-assembly. Self-assembly refers to the self-organisation of building blocks to form ordered structures. As the properties of the self-assembled materials will inherit the properties of the basic building blocks, it is then possible to engineer the properties of the materials by tailoring the properties of the building blocks. In order to create mesoscale materials, the self-assembly of molecular building blocks of different sizes and interactions is important. Mesoscopic materials can be obtained by using larger building bloc

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12

Haghighi, Fatemeh. "Prediction of ticagrelor's effect on the lipid composition and the P2Y12 receptor of platelet's membrane by molecular dynamic and docking." Thesis, Bourgogne Franche-Comté, 2019. http://www.theses.fr/2019UBFCE019.

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Les récepteurs P2Y12 constituent une cible majeure des médicaments antiplaquettaires dans le traitement préventif des évènements thromboemboliques chez les patients ayant un syndrome coronarien aigu. A ce titre, le ticagrelor, un antagoniste sélectif et réversible des récepteurs P2Y12, a une place de choix dans l’arsenal thérapeutique. L’objectif de ce travail est d’étudier les interactions entre le ticagrelor, l’ADP et les récepteurs P2Y12 et les lipides membranaires des plaquettes.Dans la première partie de ce travail, nos résultats ont montré que le ticagrelor et l’ADP modifient la composit

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13

Sandmann, Rabea. "Blood Platelet Behavior on Structured Substrates." Doctoral thesis, 2015. http://hdl.handle.net/11858/00-1735-0000-0023-9668-C.

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14

Bender, Markus. "Studies on platelet cytoskeletal dynamics and receptor regulation in genetically modified mice." Doctoral thesis, 2009. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-48390.

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Blutplättchen werden von Megakaryozyten im Knochenmark in einem Prozess produziert, an dem Aktin beteiligt ist. Aktin-Depolymerisierungsfaktor (ADF) und Cofilin sind Aktin-bindende Proteine, die als entscheidende Regulatoren im Aktinumsatz agieren, indem sie das Schneiden und Depolymerisieren von Filamenten unterstützen. Die Bedeutung von ADF/Cofilin und des Aktinumsatzes in der Bildung von Blutplättchen ist gegenwärtig nicht bekannt. In der vorliegenden Arbeit wurden Mäuse untersucht, die eine konstitutive ADF-Defizienz und/oder die eine konditionale n-Cofilin Defizienz (Cre/loxP) aufweisen.

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15

Bender, Markus [Verfasser]. "Studies on platelet cytoskeletal dynamics and receptor regulation in genetically modified mice = Untersuchungen zur Zytoskelettdynamik und Rezeptorregulation in Blutplättchen genetisch modifizierter Mäuse / submitted by Markus Bender." 2009. http://d-nb.info/1003257860/34.

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16

徐朝賢. "The Static and Dynamic Analysis of Platelets Adhered Images." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/31105886654740086827.

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碩士<br>國立成功大學<br>醫學工程研究所<br>83<br>An in vitro flow system is usually used to investigate the distribution features of adhered platelets under different flow conditions. The four controlled conditions are: (1) fibrin-coated surface, shear rate 445/s; (2) fibrincoated surface, shear rate 70/s; (3) fibrinogen-coated surface, shear rate 445/s; (4) fibrinogen-coated surface, shear rate 70/s. 　　The purpose of this study is to apply image processing technique for quantitative analysis of the platelets images. First of all, the identification of platelets is realized by sequential procedures, including

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17

Wagner, Christopher Todd. "Effects of fluid dynamic shear stress on platelet aggregability under pathophysiologic conditions." Thesis, 1997. http://hdl.handle.net/1911/19227.

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The objective of this work was to further our understanding of the influence hemodynamic forces have on the cardiovascular system. Specifically, the effect of shear stress on platelet aggregability under two pathophysiological conditions was studied. Elevated shear stress levels in stenosed vessels induce platelet aggregation. Increased plasma catecholamine concentrations have also been implicated in the onset of acute coronary ischemic syndromes. This first study was designed to examine the synergistic platelet activation by the interaction of shear stress and epinephrine. Platelets suspensio

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18

"Regulation of constitutive platelet-derived growth factor receptor degradation by the 105 kilodalton isoform of ankyrin3." Thesis, 2014. http://hdl.handle.net/10388/ETD-2014-03-1496.

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Deregulation of platelet-derived growth factor receptor (PDGFR) signaling is a driving event in glioblastoma, promotes tumor progression epithelial to mesenchymal transition (EMT) in multiple cancers, modulates the tumor stroma to facilitate tumorigenesis and reduces tumor uptake of chemotherapeutics. Previous studies identified the 105 kDa isoform of ankyrin3 (Ank105) as a binding partner of the PDGFR signaling machinery and demonstrated that expression of Ank105 promoted PDGFR degradation (Ignatiuk et al., 2006)(Ignatiuk et al., 2006)(Ignatiuk et al., 2006). Receptor tyrosine kinases are tar

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