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1

Chenna, Deepika, Shamee Shastry, and Soumya Das. "Cocktail Protocol for Preparation of Platelet-Rich Fibrin Glue for Autologous Use." Malaysian Journal of Medical Sciences 28, no. 1 (2021): 35–40. http://dx.doi.org/10.21315/mjms2021.28.1.5.

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Background: Biomaterials containing platelets have been used to promote healing of ulcers and burns, as well as in implantology and maxillofacial and plastic surgery to achieve wound healing and tissue repair. Commercial devices to prepare autologous biomaterials involve diverse preparation methods that can have high production costs and low yields. Hence, we designed a protocol for preparation of large amounts of autologous platelet-rich fibrin (PRF) glue using conventional processing techniques for blood components. Methods: Autologous whole blood collected 72 h before surgery was processed
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Yazawa, Masaki, Hisao Ogata, Tatsuo Nakajima, Taisuke Mori, Naohide Watanabe, and Makoto Handa. "Basic Studies on the Clinical Applications of Platelet-Rich Plasma." Cell Transplantation 12, no. 5 (2003): 509–18. http://dx.doi.org/10.3727/000000003108747073.

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Platelets, which contain many growth factors such as platelet-derived growth factor (PDGF) and transforming growth factor-β (TGF-β), are being used in clinical applications as platelet-rich plasma (PRP). Only a few studies, however, have been conducted on the growth factors present in PRP and on the clinical applications using the drug delivery system (DDS). For the purpose of clinical application, we first modified the PRP preparation method and assessed the amounts of growth factors contained in the human platelet concentrates. Furthermore, we assessed fibrin glue as a DDS of platelet concen
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Xiuwen, Wu, Ren Jianan, Yao Genhong, et al. "Biocompatibility, biodegradation, and neovascularization of human single-unit platelet-rich fibrin glue: an in vivo analysis." Chinese Medical Journal 127, no. 3 (2014): 408–11. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20130412.

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Background The clinical applications of fibrin glue span over several surgical modalities. The aim of this study was to evaluate the biocompatibility and biodegradation of different formulations of platelet-rich fibrin glue in vivo and examine its effects on the neovascularization of wound sites. Methods Human-derived single-unit fibrin glue was prepared. Incisions were made on the backs of rats, and these were coated with homemade glues containing different concentrations of aminomethylbenzoic acid (Groups A-F) or commercial adhesives (Group G). A sham control group was included (Group H). Th
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Tsai, Jui-Che, Shyh Ming Kuo, Shwu Jen Chang, Ioannis Manousakas, and Tim-Mo Chen. "A NOVEL TGD®DEVICE TO GENERATE THERAPEUTIC PLATELET GLUE." Biomedical Engineering: Applications, Basis and Communications 19, no. 04 (2007): 225–29. http://dx.doi.org/10.4015/s1016237207000306.

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The surgical applications of platelet glue (a mixture of platelet gel and fibrin glue) are so far particularly prominent in plastic and orthopedic surgeries. It is shown to accelerate bone fracture and wound healing in many clinical practices. Over the years, one of the components used to prepare platelet glue (PG), thrombin, could only be obtained from pooled human plasma or bovine blood after repeated centrifugation processes. The quantity from this thrombin source is limited and its process deemed time consuming and the risk of infection does exist. Here, we present a stand alone device (TG
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Valbonesi, M., G. Giannini, F. Migliori, R. Dalla Costa, and A. Galli. "The Role of Autologous Fibrin-Platelet Glue in Plastic Surgery: A Preliminary Report." International Journal of Artificial Organs 25, no. 4 (2002): 334–38. http://dx.doi.org/10.1177/039139880202500413.

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To promote wound healing, we used autologous fibrin-platelet glue in 14 patients with skin and soft tissue losses caused by recent trauma or chronic pathology. The level of improvement was scored, arbitrarily, from 0 to 4. Very favourable results (score 3–4) were seen in 11 out of 14 patients. The glue preparation is very easy, inexpensive and creates excellent and stable hemostasis. From a general point of view, we have confirmed the utility of fibrin-platelet glue in terms of reduced infections and length of hospital stay.
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Suzan, Salem, and Saad Islam. "Evaluation of Blood Banked Fibrin Glue versus Blood Banked Platelet Glue as a Local Hemosatic Agent and a Healing Promoter in Patients with Acute Leukemia Undergoing Tooth Extraction." British Journal of Medicine & Medical Research 21, no. 7 (2017): 1–13. https://doi.org/10.9734/BJMMR/2017/33470.

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<strong>Aims: </strong>The purpose of this study was to compare the effectiveness of blood banked platelet glue and blood banked fibrin glue as a local hemostatic agent after tooth extraction in patients diagnosed with acute leukemia with concomitant thrombocytopenia. <strong>Study Design:</strong> Randomized clinical trial. <strong>Place and Duration of Study:</strong> Hematology Unit, Internal Medicine Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt between June 2015 and July 2016. <strong>Methodology:</strong> 21 patients who underwent 60 dental extractions diagnos
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7

Liang, Min, Zhenzhu Li, Cengceng Gao, Fuping Wang, and Zhongmin Chen. "Preparation and characterization of gelatin/sericin/carboxymethyl chitosan medical tissue glue." Journal of Applied Biomaterials & Functional Materials 16, no. 2 (2017): 97–106. http://dx.doi.org/10.5301/jabfm.5000384.

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Background: The development and application of medical glue has been continuously expanding and advancing. However, there are few glues that combine low-cost with excellent biocompatibility. Methods: We have prepared a medical tissue glue using a gelatin (Gel), sericin (SS) and carboxymethyl chitosan (CMCS) blend solution, cross-linked with 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC). The combination’s characteristics and microstructure morphology were observed by Fourier transform infrared spectroscopy (FT-IR) and scanning electron microscope (SEM). Bond strength tests were used to m
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Norjannah, Siti, Ririn Arminsih Wulandari, and Al Asyary. "Benzene Exposure Analysis through S-Phenylmercapturic Acid in Urine at Platelet Levels in Footwear Workers in Sukajaya Village, Bogor Regency." Open Access Macedonian Journal of Medical Sciences 9, E (2021): 260–64. http://dx.doi.org/10.3889/oamjms.2021.5783.

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BACKGROUND: Benzene is a toxic and carcinogenic compound whose presence in glue is endangering the health of workers in footwear workshops. One of its negative effects is its disruption of the bone marrow, which is where red blood cells, white blood cells, and platelets are produced. AIM: The purpose of this study was to analyze the relationship of benzene exposure with platelet levels in workers through examination of S-phenylmercapturic acid (S-PMA) concentrations in urine. METHODS: The design of the study was cross sectional, with 73 workers used as samples. The concentration of S-PMA was m
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Chen, Tim Mo, Jui-Che Tsai, and Thierry Burnouf. "Cranioplasty Using Osteoconductive Scaffold and Platelet Glue." Journal of Trauma: Injury, Infection, and Critical Care 65, no. 6 (2008): 1321–27. http://dx.doi.org/10.1097/ta.0b013e3181574edf.

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Burnouf, T., C. Y. Su, M. Radosevich, H. Goubran, and M. El-Ekiaby. "Blood-derived biomaterials: fibrin sealant, platelet gel and platelet fibrin glue." ISBT Science Series 4, no. 1 (2009): 136–42. http://dx.doi.org/10.1111/j.1751-2824.2009.01222.x.

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Hermeto, Larissa Correa, Rafael de Rossi, Santiago Benites de Pádua, Elenir Rose Jardim Pontes, and Aureo Evangelista Santana. "Comparative study between fibrin glue and platelet rich plasma in dogs skin grafts." Acta Cirurgica Brasileira 27, no. 11 (2012): 789–94. http://dx.doi.org/10.1590/s0102-86502012001100008.

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PURPOSE: Compare fibrin glue (Tissucol®) and platelet-rich plasma in full-thickness mesh skin grafts in dogs. METHODS: Eighteen dogs were used, divided into two groups: fibrin glue (FG) and platelet-rich plasma (PRP). In all the animals, a full-thickness 3x3 cm mesh skin graft was implanted. In the left limb, the biomaterial was place between the graft and the receptor bed, according to the group, while the right limb served as the control group. All the animals were evaluated clinically every 48 hours until the 14th day, using the variables of exudation, coloration, edema and cosmetic appeara
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12

Green, David M., and Brian Klink. "PLATELET GEL AS AN INTRAOPERATIVELY PROCURED PLATELET-BASED ALTERNATIVE TO FIBRIN GLUE." Plastic & Reconstructive Surgery 101, no. 4 (1998): 1161. http://dx.doi.org/10.1097/00006534-199804040-00067.

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13

Oz, Mehmet C., Valluvan Jeevanandam, Craig R. Smith, et al. "Autologous fibrin glue from intraoperatively collected platelet-rich plasma." Annals of Thoracic Surgery 53, no. 3 (1992): 530–31. http://dx.doi.org/10.1016/0003-4975(92)90291-b.

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14

Dascombe, William H., Gregory Dumanian, Chull Hong, et al. "Application of Thrombin Based Fibrin Glue and Non-Thrombin Based Batroxobin Glue on Intact Human Blood Vessels: Evidence for Transmural Thrombin Activity." Thrombosis and Haemostasis 78, no. 02 (1997): 947–51. http://dx.doi.org/10.1055/s-0038-1657657.

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SummaryAn alternative method of uniting small diameter vessels to obtain tissue union while limiting the thrombogenic effect of suture placement at a vessel anastomosis involves the use of a thrombin based fibrin glue as a surgical sealant. This investigation addresses whether the in vitro application of a thrombin based glue (TG), or batroxobin glue (BG), a non-thrombin based glue made with the snake venom enzyme batroxobin, alters intravascular platelet deposition (PD) or cleaves blood fibrinogen, as measured by fibrinopeptide A (FPA) production, when the respective glue is applied to the ex
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Aslam, Sohail, Adnan Asghar, Syed Muhammad Asad Shabbir Bukhari, Sunarays Akhtar, Hamza Mumtaz, and Muhammad Fahad Waseem. "ROLE OF FIBRIN GLUE FOR BETTER SUCCESS RATE IN MYRINGOPLASTY." PAFMJ 71, Suppl-3 (2021): S603–06. http://dx.doi.org/10.51253/pafmj.v71isuppl-3.4298.

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Objective: To see graft uptake success rate in platelet rich fibrin aided underlay myringoplasties using temporalis fascia graft compared to conventional underlay myringoplasties.&#x0D; Study Design: Double blind randomized controlled trial study.&#x0D; Place and Duration of Study: ENT department, Pakistan Naval Ship Shifa Hospital, from Jan to Jun 2019.&#x0D; Methodology: Sixty cases with dry central tympanic membrane perforations were recruited. The patients suffering from sensori-neural hearing loss and co-morbidities like diabetes were excluded. The sampling technique was probability simpl
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Ghiasi, Mahdieh. "Regeneration of Cartilage Tissue by Comparing the Natural and Synthetic Biomaterials during ADSCs Differentiation." Journal of Orthopedics & Bone Disorders 7, no. 1 (2023): 1–9. http://dx.doi.org/10.23880/jobd-16000231.

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Objectives: Human adipose-derived stem cells have shown chondrogenic differentiation for cartilage engineering. In the present study, we evaluated different scaffolds for chondrogenic differentiation of Human adipose-derived stem cells. Methods: cells were cultured and chondrogenic differentiation was investigated in Polycaprolactone, Platelet Rich Plasma, and Fibrin glue scaffolds by MTT, Real time and histology. Results: Cell proliferation and collagen levels in Platelet Rich Plasma scaffolds were significantly higher than other scaffolds. The levels of Sox9 and col II were up regulated in P
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Titani, Koiti, and Kenneth A. Walsh. "Human von Willebrand factor: The molecular glue of platelet plugs." Trends in Biochemical Sciences 13, no. 3 (1988): 94–97. http://dx.doi.org/10.1016/0968-0004(88)90048-5.

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18

Man, Daniel, Harvey Plosker, and Jill E. Winland-Brown. "The Use of Autologous Platelet-Rich Plasma (Platelet Gel) and Autologous Platelet-Poor Plasma (Fibrin Glue) in Cosmetic Surgery." Plastic and Reconstructive Surgery 107, no. 1 (2001): 238–39. http://dx.doi.org/10.1097/00006534-200101000-00038.

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Man, Daniel, Harvey Plosker, and Jill E. Winland-Brown. "The Use of Autologous Platelet-Rich Plasma (Platelet Gel) and Autologous Platelet-Poor Plasma (Fibrin Glue) in Cosmetic Surgery." Plastic and Reconstructive Surgery 107, no. 1 (2001): 229–36. http://dx.doi.org/10.1097/00006534-200101000-00037.

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Valbonesi, Mauro. "Fibrin glue and cryo-platelet gel for surgical application in Italy." Transfusion and Apheresis Science 30, no. 2 (2004): 137–38. http://dx.doi.org/10.1016/j.transci.2004.01.002.

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Schettino, Angélica Maria, Diogo Franco, Talita Franco, João Medeiros Tavares Filho, and Fabiel Spani Vendramin. "Use of Autologous Fibrin Glue (Platelet-Poor Plasma) in Abdominal Dermolipectomies." Aesthetic Plastic Surgery 36, no. 6 (2012): 1296–301. http://dx.doi.org/10.1007/s00266-012-9978-y.

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Hamidi-Alamdari, Daryoush, Maryam Joudi, Mehran Hyradfar, et al. "Successful treatment of congenital chylous ascites with platelet-rich fibrin glue." Clinical Biochemistry 44, no. 13 (2011): S60—S61. http://dx.doi.org/10.1016/j.clinbiochem.2011.08.1073.

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23

Gutowski, K. A. "Use of Autologous Fibrin Glue (Platelet-Poor Plasma) in Abdominal Dermolipectomies." Yearbook of Plastic and Aesthetic Surgery 2015 (2015): 104. https://doi.org/10.1016/j.yprs.2013.11.019.

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24

Qureshi, Ahsan, Nisar Akber Khan, Muhammad Saleem, et al. "An Investigation on the Fibrin Glue's Impact on Myringoplasty's Success Rate: A Randomized Controlled Study." Pakistan Journal of Medical and Health Sciences 17, no. 4 (2023): 655–57. http://dx.doi.org/10.53350/pjmhs2023174655.

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Objective: The study's goal is to evaluate the success rates of graft uptake in platelet-rich fibrin-assisted underlay myringoplasties employing temporalis fascia grafts to those in traditional underlay myringoplasties. Methods: This study was conducted in Mayo Hospital in Lahore's ENT department carried out this double-blind, randomized, controlled trial investigation. We recruited 60 individuals with dry central tympanic membrane perforations. Patients with co-morbidities such as diabetes and sensorineural hearing loss were not included. Probability basic random sampling was used. The patien
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Shirvan, Maliheh Keshvari, Daryoush Hamidi Alamdar, Alireza Ghorifi, and Hamid Reza Rahimi. "A Novel Treatment for Urethrovaginal Fistula: Autologous Platelet-Rich–Plasma Injection and Platelet-Rich–Fibrin-Glue Interposition." Journal of Gynecologic Surgery 29, no. 5 (2013): 268–70. http://dx.doi.org/10.1089/gyn.2013.0011.

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Zhu, Shi-Jiang, Byung-Ho Choi, Jae-Hyung Jung, et al. "A comparative histologic analysis of tissue-engineered bone using platelet-rich plasma and platelet-enriched fibrin glue." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 102, no. 2 (2006): 175–79. http://dx.doi.org/10.1016/j.tripleo.2005.08.034.

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Sanghani-Kerai, Anita, Melanie Coathup, Robyn Brown, et al. "The development of a novel autologous blood glue aiming to improve osseointegration in the bone-implant interface." Bone & Joint Research 9, no. 7 (2020): 402–11. http://dx.doi.org/10.1302/2046-3758.97.bjr-2019-0073.r3.

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Aims For cementless implants, stability is initially attained by an interference fit into the bone and osteo-integration may be encouraged by coating the implant with bioactive substances. Blood based autologous glue provides an easy, cost-effective way of obtaining high concentrations of growth factors for tissue healing and regeneration with the intention of spraying it onto the implant surface during surgery. The aim of this study was to incorporate nucleated cells from autologous bone marrow (BM) aspirate into gels made from the patient’s own blood, and to investigate the effects of incorp
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Tashnizi, Mohhamad Abbasi, Mahmood Hossinzadeh Maleki, Omid Javedanfar, et al. "Platelet-rich plasma fibrin glue for treatment of chylothorax following cavopulmonary connections." European Journal of Cardio-Thoracic Surgery 58, no. 6 (2020): 1269–73. http://dx.doi.org/10.1093/ejcts/ezaa243.

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Abstract OBJECTIVES The postoperative persistence of chylothorax is a fatal complication of paediatric cardiac surgery. There is an urgent need for an effective treatment of chylothorax. This study reports the application of allogenic platelet-rich plasma fibrin glue (PRP-FG) as a conservative therapy before reoperation. METHODS Over a 9-year period, from 2010 to 2019, 27 patients with persistent chylothorax following a cavopulmonary connection, with a mean latency period of 11 days (range 10–15 days), were treated with PRP-FG. These patients were selected because they had not responded positi
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Giannini, Gabriella, Valbonesi Mauro, Tel Agostino, and Bindi Gianfranco. "Use of autologous fibrin-platelet glue and bone fragments in maxillofacial surgery." Transfusion and Apheresis Science 30, no. 2 (2004): 139–44. http://dx.doi.org/10.1016/j.transci.2003.11.009.

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Von Knorring, Lars, and Lars Oreland. "Personality traits and platelet monoamine oxidase in tobacco smokers." Psychological Medicine 15, no. 2 (1985): 327–34. http://dx.doi.org/10.1017/s0033291700023606.

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SynopsisA study was made of the smoking habits of an unselected series of 1129 18-year-old men from the general population. Their smoking habits were related to personality traits, intellectual level and platelet monoamine oxidase (MAO). Regular smokers were found to be extraverts, sensation seekers who were easily bored and with a strong tendency to avoid monotony. They also had a lower than average intellectual level, and were more prone to the abuse of alcohol, glue, cannabis, amphetamine and morphine. Furthermore, they had a low platelet MAO.The results are discussed in relation to the pha
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Ananthakrishnan Nair, Manju, Khadar Vali Shaik, Adiseshu Kokkiligadda, and Harsha Gorrela. "Tissue-engineered Maxillofacial Skeletal Defect Reconstruction by 3D Printed Beta-tricalcium phosphate Scaffold Tethered with Growth Factors and Fibrin Glue Implanted Autologous Bone Marrow-Derived Mesenchymal Stem Cells." Journal of Medicine and Life 13, no. 3 (2020): 418–25. http://dx.doi.org/10.25122/jml-2020-0044.

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The study aimed to investigate whether a 3D printed beta-tricalcium phosphate (β-TCP) scaffold tethered with growth factors and fibrin glue implanted autologous bone marrow-derived mesenchymal stem cells would provide a 3D platform for bone regeneration resulting in new bone formation with plasticity. Twenty 3D printed β-TCP scaffolds, ten scaffolds engrained with osteogenic mesenchymal stem cells with fibrin glue (group A), and ten scaffolds used as a control group with β-TCP scaffold and fibrin glue inoculation only (group B) were included in the study. Cell infiltration, migration, and prol
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Kozlova, Yu V., S. V. Churashov, A. N. Kulikov, A. Yu Malafeeva, V. V. Karpovich, and A. G. Ianushko. "Autolimbal Transplantation and Two-component Autofibrin Glue in the Treatment of Repeatedly Recurrent Pterygium." Ophthalmology in Russia 22, no. 1 (2025): 41–46. https://doi.org/10.18008/1816-5095-2025-1-41-46.

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We have proposed a method for fixing an autolimbal graft using a two-component autofibrin glue. The use of this adhesive composition is justified by the formation for strong adhesion and tissues fixation, as well as the relief of local inflammatory reaction due to the platelet-rich plasma (PRP) included in its composition.Objective. To compare the effectiveness of autolimbal transplantation using a two-component autofibrin glue and suture fixation in multiple recurring pterygium over a two-year follow-up period.Patients and methods. The study included 19 patients (20 eyes) with repeatedly recu
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Daglioglu, Yusuf Kenan, Ozgul Duzgun, Inanc Samil Sarici, and Kemal Turker Ulutas. "Comparison of platelet rich plasma versus fibrin glue on colonic anastomoses in rats." Acta Cirurgica Brasileira 33, no. 4 (2018): 333–40. http://dx.doi.org/10.1590/s0102-865020180040000005.

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Joudi, Marjan, Daryoush Hamidi Alamdari, Mehran Hyradfar, et al. "Lateral Traumatic Esophago-Cutaneous fistula in a Child; Platelet-Rich Fibrin Glue Challenge." Iranian Red Crescent Medical Journal 15, no. 3 (2013): 256–9. http://dx.doi.org/10.5812/ircmj.7975.

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Tsai, Chun-Hao, Horng-Chaung Hsu, Yen-Jen Chen, Mou-Jyn Lin, and Hsien-Te Chen. "Using the Growth Factors-enriched Platelet Glue in Spinal Fusion and its Efficiency." Journal of Spinal Disorders & Techniques 22, no. 4 (2009): 246–50. http://dx.doi.org/10.1097/bsd.0b013e3181753ae2.

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Zarge, Joseph I., Vicki Husak, Peter Huang, and Howard P. Greisler. "Fibrin glue containing fibroblast growth factor type 1 and heparin decreases platelet deposition." American Journal of Surgery 174, no. 2 (1997): 188–92. http://dx.doi.org/10.1016/s0002-9610(97)00090-1.

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Ren, Jianan, Xiuwen Wu, Zhiwu Hong, and Jieshou Li. "Management of a Patient with Colocutaneous Fistula by Autologous Platelet-rich Fibrin Glue." American Surgeon 78, no. 2 (2012): 86–87. http://dx.doi.org/10.1177/000313481207800215.

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Joudi, Marjan, Daryoush Hamidi-Alamdari, Mehran Hyradfar, Mehdi Fathi, Reza Shojaeian, and Mohammad Gharavi. "Lateral traumatic cutaneo-esophageal fistula in a child; platelet-rich fibrin glue challenge." Clinical Biochemistry 44, no. 13 (2011): S180. http://dx.doi.org/10.1016/j.clinbiochem.2011.08.935.

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International, Journal of Medical Science and Innovative Research (IJMSIR). "Comparing The Role of Mesenchymal Stem Cell Glue (MSCS) With Platelet Rich Fibrin (PRF) Gel in Treating Abrasions." International Journal of Medical Science and Innovative Research (IJMSIR) 9, no. 5 (2024): 94–102. https://doi.org/10.5281/zenodo.15436856.

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<strong>Abstract</strong> <strong>Introduction: </strong>Abrasions are minor injuries to the body's skin and inner linings that can be seen on any part of the body, but are most commonly found on the forehead, nose tip, cheek, and chin region. Though, facial abrasions are superficial injuries, but it can also lead to unacceptable scars and appearances. &nbsp;Hence, using the autologous medium as a dressing material over these abrasions can substantially reduce the tendency of scar and hyperpigmentation. A blood clot serves as the focal point for healing, with 95% red blood cells and 5% platele
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Shirvan, Maliheh Keshvari, Daryoush Hamidi Alamdari, and Alireza Ghoreifi. "A Novel Method for Iatrogenic Vesicovaginal Fistula Treatment: Autologous Platelet Rich Plasma Injection and Platelet Rich Fibrin Glue Interposition." Journal of Urology 189, no. 6 (2013): 2125–29. http://dx.doi.org/10.1016/j.juro.2012.12.064.

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Khitaryan, A. G., A. V. Mezhunts, K. S. Oplimakh, et al. "Biological therapy of bariatric surgery complications." Ambulatornaya khirurgiya = Ambulatory Surgery (Russia) 21, no. 1 (2024): 84–90. http://dx.doi.org/10.21518/akh2024-011.

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In recent years, the number of performed bariatric interventions has increased significantly. Despite the high effectiveness of this method of treatment, the occurrence of complications is not uncommon. The most common complications are stapler line leaks, occurring in 1.5–2.4% of cases; anastomotic leakage after One Anastomosis Gastric Bypass – in 2.2–8% of cases. The problem with all methods is the increased duration of treatment and the need to go without food for significant periods of time, which means starting parenteral nutrition and risking malnutrition. The article demonstrates the ef
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Bhalla, R. K., and T. H. J. Lesser. "Simple, painless, cosmetic closure of endaural incisions." Journal of Laryngology & Otology 117, no. 1 (2003): 67–68. http://dx.doi.org/10.1258/002221503321046685.

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Endaural incisions provide a cosmetic approach to the middle-ear cleft, tympanic membrane for myringoplasty, and attic and antrum for small cavity mastoidectomy. These wounds have traditionally been closed with sutures, but platelet or fibrin adhesives provide an alternative. However, discomfort at the time of suture removal, particularly in children, and the risk of transmission of blood-borne infections in gels are limitations to these wound closure techniques. This paper describes our experience with Histoacryl® glue (butyl-2-cyanoacrylate) in closing endaural incisions.
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Manin, Emily, Gianmarco Taraschi, Sarah Berndt, Begoña Martinez de Tejada, and Jasmine Abdulcadir. "Autologous Platelet-Rich Plasma for Clitoral Reconstruction: A Case Study." Archives of Sexual Behavior 51, no. 1 (2021): 673–78. http://dx.doi.org/10.1007/s10508-021-02172-9.

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AbstractClitoral reconstruction after female genital mutilation/cutting (FGM/C) is associated with significant post-operative pain and months-long recovery. Autologous platelet-rich plasma (A-PRP) reduces the time of healing and pain in orthopedic and burn patients and could also do so in clitoral reconstruction. In the present case, a 35-year-old Guinean woman who had undergone FGM/C Type IIb presented to our clinic for clitoral reconstruction. Her request was motivated by low sexual satisfaction and body image. We surgically reconstructed the clitoris using the Foldès method and applied plas
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Findikcioglu, Fulya, Kemal Findikcioglu, Reha Yavuzer, Nese Lortlar, and Kenan Atabay. "Effect of Intraoperative Platelet-Rich Plasma and Fibrin Glue Application on Skin Flap Survival." Journal of Craniofacial Surgery 23, no. 5 (2012): 1513–17. http://dx.doi.org/10.1097/scs.0b013e3182597ce6.

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Huh, Jin-Young, Byung-Ho Choi, Shi-Jiang Zhu, Jae-Hyung Jung, Byung-Yong Kim, and Seoung-Ho Lee. "The effect of platelet-enriched fibrin glue on bone regeneration in autogenous bone grafts." Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 101, no. 4 (2006): 426–31. http://dx.doi.org/10.1016/j.tripleo.2005.06.010.

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Chen, Tim-Mo, Yuan-Sheng Tzeng, Jui-Che Tsai, and Thierry Burnouf. "Single-Donor Allogeneic Platelet Fibrin Glue and Osteoconductive Scaffold in Orbital Floor Fracture Reconstruction." Annals of Plastic Surgery 70, no. 3 (2013): 370–74. http://dx.doi.org/10.1097/sap.0b013e31823b6880.

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Rezapanah, Alireza, Elaheh Emadi, and Daryoush Hamidi Alamdari. "Treatment of recalcitrant esophagocutaneous fistula by platelet-rich-plasma-fibrin glue: A case study." International Journal of Surgery Case Reports 116 (March 2024): 109335. http://dx.doi.org/10.1016/j.ijscr.2024.109335.

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Ameida, Flavio X., Khalila C. Cotrim, Eduardo C. Kalil, et al. "Is there an effective way to control pain perception after free gingival graft removal? A systematic review and meta-analysis." Brazilian Dental Journal 34, no. 6 (2023): 10–29. http://dx.doi.org/10.1590/0103-6440202305503.

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Abstract The literature describes multiple ways to stimulate wound healing to reduce the patient's perception of pain. This systematic review aimed to evaluate if methods that enhance wound healing can reduce the patient’s perception of pain after free gingival graft removal from the palate region compared to natural healing. A systematic review protocol was written following the PRISMA checklist. Electronic searches of five databases were performed to identify randomized clinical trials (RCTs) that assessed the patient’s perception of pain after the removal of a free gingival graft from the p
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Siriex, Didier, Eric Chemla, Yves Castier, Simone Massonnet-Castel, Jean Noël, and Jean-François Baron. "Comparative Study of Different Biological Glues in an Experimental Model of Surgical Bleeding in Anesthetized Rats: Platelet-Rich and -Poor Plasma-Based Glue with and without Aprotinin versus Commercial Fibrinogen-Based Glue." Annals of Vascular Surgery 12, no. 4 (1998): 311–16. http://dx.doi.org/10.1007/s100169900160.

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Waldner, Matthias, Tarek Ismail, Alexander Lunger, et al. "Evolution of a concept with enzymatic debridement and autologous in situ cell and platelet-rich fibrin therapy (BroKerF)." Scars, Burns & Healing 8 (January 2022): 205951312110523. http://dx.doi.org/10.1177/20595131211052394.

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Background Deep partial-thickness burns are traditionally treated by tangential excision and split thickness skin graft (STSG) coverage. STSGs create donor site morbidity and increase the wound surface in burn patients. Herein, we present a novel concept consisting of enzymatic debridement of deep partial-thickness burns followed by co-delivery of autologous keratinocyte suspension and plated-rich fibrin (PRF) or fibrin glue. Material and methods In a retrospective case study, patients with deep partial-thickness burns treated with enzymatic debridement and autologous cell therapy combined wit
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