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Journal articles on the topic 'Plateletcrit'

Author: Grafiati

Published: 5 June 2025

Last updated: 16 July 2025

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Akpinar, I., M. R. Sayin, Y. C. Gursoy, et al. "Plateletcrit." Herz 39, no. 1 (2013): 142–48. http://dx.doi.org/10.1007/s00059-013-3798-y.

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Krishnan, Gokul, M. Mukhyaprana Prabhu, and Weena Stanley. "Platelet indices as diagnostic and prognostic markers in acute coronary syndrome." F1000Research 13 (August 15, 2024): 927. http://dx.doi.org/10.12688/f1000research.152404.1.

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Background Acute coronary syndromes refer to STEMI, NSTEMI and unstable angina. The preferred biomarkers for assessing myocardial damage are cTnI and cTnT, and high-sensitivity cardiac troponin assays are recommended in clinical practice. Other biomarkers such as CK-MB have lower sensitivity and specificity. Platelets play a major role in thrombosis, which is a causative factor for most acute coronary syndromes. In our study, we attempted to analyze the effectiveness of platelet indices (mean platelet volume, platelet count, and platelet distribution width) as diagnostic and prognostic markers in acute coronary syndromes. Our data suggest that mean platelet volume and platelet distribution width are potential diagnostic markers, and plateletcrits can serve as prognostic markers. Methods A total of 290 subjects were recruited for the study, including 145 cases and 145 controls matched for sex and age. Cases presented with the first episode of acute coronary syndrome. Controls are those without acute coronary syndrome during present admission or in the past. Results MPV and plateletcrit correlated with both troponin T and pro-BNP, whereas PDW showed a positive correlation only with troponin T. The only significant correlation was between the plateletcrit and pro-BNP levels. The plateletcrit showed a positive correlation with other parameters (degree of ventricular dysfunction, severity of coronary artery disease, and presence of arrhythmia). On comparing platelet indices with risk factors for coronary artery disease, such as diabetes mellitus and dyslipidemia, MPV showed a positive correlation with HbA1c and the entire lipid profile, whereas PDW showed a positive correlation only with HbA1c and triglycerides. The plateletcrit was positively correlated with HbA1c and total cholesterol levels. Conclusions Our data suggest that mean platelet volume and platelet distribution width are potential diagnostic markers, whereas plateletcrits can serve as prognostic markers.

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Jevtić, Dalibor, Slavoljub Janković, Danijela Marković, Milena Jevtić, Milan Đorđević, and Aleksa Janković. "Incidence of PCT (plateletcrit) decrease in COVID-19 positive patients: Diagnostic and epidemiologic value." Opsta medicina, no. 00 (2024): 12. http://dx.doi.org/10.5937/opmed0-47424.

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Introduction: Platelets play an important role in the pathogenesis of COVID-19. Therefore, their parameters vary in different stages of the disease. The importance of plateletcrit in COVID-19 is not well known. Objective: To examine the diagnostic value of plateletcrit in COVID-19. Methods: From January to March and September-December 2021. during their initial visit to the COVID outpatient clinic at the Primary Healthcare Center Nis, we examined 440 patients who were experiencing possible COVID-19 symptoms. Following the examination, a complete blood count was performed, and they tested positive for COVID-19. We analyzed the plateletcrit in every lab sample collected during their first visit. The control group consisted of 60 patients from the "green zone" from January to December 2021, as well as 48 patients from the pre-COVID period, before 2020. Results: Lower plateletcrit was found in 48,4% of women and 63,3% of men in the first period. Out of the total of 111 patients, lower plateletcrit was found in 54,9%. in the second period lower plateletcrit was found in 72,2% of women and 85% of men. Out of the total number of 329 patients, lower plateletcrit was found in 78,7%. In the control group, from the "green zone" lower plateletcrit was found in 8,3% of 60 patients, and no decrease in plateletcrit levels was observed in 48 patients from the pre-COVID-19 era. Conclusion: Plateletcrit levels are decreased in many patients during their initial visit due to COVID-19. Symptoms. Therefore, variations in plateletcrit levels could raise concerns about potential COVID-19 infection.

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Cerit, Levent, and Zeynep Cerit. "Relationship between coronary tortuosity and plateletcrit coronary tortuosity and plateletcrit." Cardiovascular Journal of Africa 28, no. 6 (2017): 385–88. http://dx.doi.org/10.5830/cvja-2017-023.

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Aslan, Serkan, Ali Rıza Demir, Yusuf Demir, et al. "Usefulness of plateletcrit in the prediction of major adverse cardiac and cerebrovascular events in patients with carotid artery stenosis." Vascular 27, no. 5 (2019): 479–86. http://dx.doi.org/10.1177/1708538119847898.

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Objectives Platelets play an important role in the pathogenesis of atherosclerosis and the physiopathology of cardiovascular events. Plateletcrit provides complete information on total platelet mass. The relationship between plateletcrit values and long-term outcomes in patients with carotid stenosis is not known. The purpose of the present study is to evaluate the reliability of plateletcrit for predicting major adverse cardiac and cerebrovascular events (MACCE) in patients with carotid stenosis. Methods A total of 230 patients with more than 50% stenosis of the carotid artery were retrospectively included in this study. All cases were divided into two groups according to the calculated threshold value of plateletcrit with receiver operating characteristics curve and baseline parameters and clinical outcomes were compared. Univariate and multivariate analyses were used to evaluate the association between the plateletcrit and MACCE. Results The cut-off value for plateletcrit was found to be 0.233 for predicting MACCE, with 56.2% sensitivity and 68.0% specificity. High plateletcrit levels were demonstrated to be statistically higher in patients with MACCE (0.247 in the MACCE (+) group vs. 0.213 in the MACCE (–) group, p < 0.001). In the Kaplan–Meier survival analysis, the long-term mortality rate was higher in the high plateletcrit group ( p = 0.006). Multivariate regression analysis showed that plateletcrit was independently associated with MACCE (OR: 2.196, CI: 1.200–4.018; p = 0.011). Conclusions Our data suggest that plateletcrit has an independently predictive value for long-term mortality and MACCE, and it can be used as a marker to predict the long-term adverse outcomes in patients with carotid stenosis.

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Wang, Jing-Jing, Yin-Ling Wang, Xin-Xin Ge, et al. "Prognostic Values of Platelet-Associated Indicators in Resectable Lung Cancers." Technology in Cancer Research & Treatment 18 (January 1, 2019): 153303381983726. http://dx.doi.org/10.1177/1533033819837261.

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Background: Lung cancer is the leading cause of cancer death. Platelet-related indictors, including platelet count, plateletcrit, mean platelet volume, and platelet distribution width, not only associate with morphology and functions of platelet but also correlate with tumor development and metastasis. In the present study, we investigated the values of platelet-related indictors in the prognosis evaluation of resectable lung cancers. Methods: In total, 101 patients with resectable lung cancer were recruited in this study. Patients were divided into 2 groups according to the median pretreatment values. To evaluate the individual value changes after treatment, we introduced the concept of post-/pretreatment ratio (≤1 indicated value was not increased after treatment, while >1 suggested increased value). Results: The high pretreatment platelet count level was correlated with larger tumor size. High pretreatment plateletcrit level was associated with more lymph nodes metastasis. Patients with high pretreatment plateletcrit level had worse overall survival, whereas pretreatment platelet count, mean platelet volume, and platelet distribution width levels were not correlated with outcomes. Surgery had no impact on the values of platelet count, plateletcrit, mean platelet volume, or platelet distribution width. Adjuvant chemotherapy significantly decreased the values of platelet count and plateletcrit, whereas it had no effect on the values of mean platelet volume or platelet distribution width. Whole course of treatment (surgery combined with adjuvant chemotherapy) significantly decreased the values of platelet count and platelet distribution width, whereas it had no effect on the values of plateletcrit or mean platelet volume. Post-/pretreatment platelet count, plateletcrit, mean platelet volume, and platelet distribution width ratios were not correlated with outcomes. Univariate analyses demonstrated that American Joint Committee on Cancer stage and pretreatment plateletcrit level were significant risk factors for prognosis. Cox regression analysis revealed that no factor independently associated with worse survival. Conclusion: Pretreatment plateletcrit level could be a potential prognostic factor in resectable lung cancers.

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Ugaragol, Prasad G., Naveen V. Charantimath, and S. J. Sanketh. "Platelet/albumin ratio and plateletcrit levels are potential new biomarkers for assessing acute myocardial infarction: hospital based cross sectional study." International Journal of Research in Medical Sciences 12, no. 11 (2024): 4180–84. http://dx.doi.org/10.18203/2320-6012.ijrms20243369.

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Background: Platelet activation plays a key role in acute myocardial infarction (AMI). Plateletcrit and platelet/albumin ratio are potential new biomarkers, but their diagnostic accuracy for AMI is unclear. Methods: This was a hospital-based cross-sectional study on 90 patients- 45 with AMI, 45 with unstable angina (UA). Plateletcrit and platelet/albumin ratio were compared between groups and ROC analysis was done to determine predictive accuracy for AMI. Results: Plateletcrit (0.49±0.04 versus 0.35±0.03, p<0.001) and platelet/albumin ratio (0.85±0.12 versus 0.65±0.09, p<0.001) were significantly higher in the AMI group compared to UA group. At a cutoff of 0.42, plateletcrit had 92% sensitivity and 89% specificity for diagnosing AMI. Platelet/albumin ratio >0.72 differentiated AMI from UA with 82% sensitivity and 84% specificity. Conclusions: Plateletcrit and platelet/albumin ratio were significantly elevated in AMI compared to UA patients. These biomarkers demonstrated good diagnostic accuracy for detecting AMI at admission. Further large-scale studies are warranted to validate these findings before incorporating into clinical practice.

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Citirik, Mehmet. "Central retinal vein occlusion associated with platelet activation." Therapeutic Advances in Ophthalmology 11 (January 2019): 251584141986484. http://dx.doi.org/10.1177/2515841419864844.

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Purpose:The aim of this article is to determine and compare the platelet activation by three main platelet activation parameters: mean platelet volume, platelet distribution width, and plateletcrit in patients with central retinal vein occlusion and control subjects.Methods:This study included 30 patients with nonischemic central retinal vein occlusion and 30 control subjects. The levels of mean platelet volume, platelet distribution width, and plateletcrit were measured in all groups.Results:The mean serum level of mean platelet volume was 10.01 ± 0.89 fl in central retinal vein occlusion group and 8.74 ± 1.45 fl in control group. The mean serum level of platelet distribution width was 14.31 ± 1.49% and 11.65 ± 1.81% in central retinal vein occlusion group and control group, respectively. Mean serum plateletcrit value was 0.27 ± 0.07% in central retinal vein occlusion group and 0.23 ± 0.07% in control group. Mean platelet volume, platelet distribution width, and plateletcrit levels were significantly higher in central retinal vein occlusion patients than controls ( p < 0.05).Conclusion:Subclinical platelet activation reflected by mean platelet volume, platelet distribution width, and plateletcrit may have an impact on the genesis of vessel occlusion in central retinal vein occlusion. The results may be important for the clinical management of patients with central retinal vein occlusion.

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Yazgan, Serpil, Ugur Celik, Havva Kaldrm, Orhan Ayar, and Mehmet Orcun Akdemir. "Plateletcrit in Ocular Pseudoexfoliation Syndrome." Eye & Contact Lens: Science & Clinical Practice 42, no. 5 (2016): 328–32. http://dx.doi.org/10.1097/icl.0000000000000197.

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Rani, Anupam, Urmila Karya, and Sakshi Nehra. "Significance of maternal hemogram parameters as new inflammatory markers for prediction of threatened preterm labor and preterm premature rupture of membranes." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 12, no. 6 (2023): 1701–5. http://dx.doi.org/10.18203/2320-1770.ijrcog20231539.

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Background: Non-invasive, inexpensive and easily available simple markers are needed for timely prediction of preterm labor and preterm premature rupture of membranes (PPROM) in women at risk. Aims and objectives of current study was to study the significance of maternal hemogram parameters i.e., NLR, PLR, MPV, PDW and plateletcrit in TPL, PPROM. Methods: A total number of 150 pregnant women, 50 with PPROM (group 1), 50 with TPL (group 2) and 50 gestation matched healthy controls (group 3) attending antenatal clinic and labor room in SVBP Hospital and associated LLRM Medical College, Meerut were recruited in study. Complete blood count was done from blood sample collected in EDTA vials using 5-part automated cell analyzer device. Hematological parameters like NLR, PLR, MPV, PDW and plateletcrit were measured from CBC. Results: Patients with PPROM had increased NLR, PLR, MPV, PWD and plateletcrit than patients with threatened preterm labor group and healthy control group. Conclusions: NLR, PLR, MPV, PDW, and Plateletcrit were significantly increased in both PPROM group and TPL group compared to healthy control group and have a predictive value in PPROM and TPL. Monitoring of these parameters can be promising and cost-effective methods in prediction of TPL and PPROM.

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Yildiz, Saliha, and Elif Eker. "Platelet indices in graves disease, especially plateletcrit." Medicine Science | International Medical Journal 9, no. 2 (2020): 338. http://dx.doi.org/10.5455/medscience.2019.08.9194.

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Beyan, Cengiz, and Esin Beyan. "Plateletcrit in patients with gestational diabetes mellitus." Journal of Obstetrics and Gynaecology 36, no. 7 (2016): 885. http://dx.doi.org/10.1080/01443615.2016.1205569.

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Patel, Keyuri Bharat, Mustafa Fakaruddin Ranapurwala, and Anjali Patel. "Utility of Red Cell and Platelet Indices Evaluation of Severity of Dengue Infection." Annals of Pathology and Laboratory Medicine 9, no. 5 (2022): A83–88. http://dx.doi.org/10.21276/apalm.3156.

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Context: Dengue is the most common mosquito-borne viral illness in humans and transmitted by aedes aegypti. Infection may be asymptomatic or present with a mild febrile illness to a life-threatening shock syndrome and diagnosed by virological tests, serological tests, and complete blood count. Aim: The present study was undertaken to evaluate the role of red cell and platelet indices to assess disease activity and severity of dengue infection. Material and Methods: The present study was conducted at a tertiary level teaching hospital in Central Gujarat, India from November 2019 to August 2021.100 dengue positive cases and 100 controls (dengue negative case) were consecutively sampled. Epidemiological, clinical data and complete blood count were collected from online and offline registers of the Central Diagnostic Laboratory. Chi square test, independent sample T – test and Karl pearson coefficient of correlation were used for statistical analysis. Results: Dengue cases have frequently presented with fever 32.65% or fever with chills / rigor 66.33%, headache 37.76%, body ache 44.90% and bleeding manifestations like petechiae 5.10% and bleeding from gum, nose and rectum 5.15%. while, 18% cases have ascites and 07% cases were found to have pleural effusion in dengue positive cases. Haemoconcentration, fall in total WBC count, platelet count and plateletcrit have significant statistical association with severity of dengue infection. Platelet count was directly proportional to plateletcrit in dengue positive cases. Conclusion: Significant statistical association was presented between degree of leukopenia, thrombocytopenia, haemoconcentration and fall in plateletcrit with severity of dengue infection whereas plateletcrit has positive correlation with platelet count in dengue infection.

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Mushtaq, Huma, Muhammad Shabbir, Shahid Mukarram, and Maria Altaf. "Association of Admission Platelet Crit with In-Hospital Outcomes in Non ST-Elevation Myocardial Infarction (NSTEMI)." Pakistan Armed Forces Medical Journal 75, SUPPL-3 (2025): S397—S403. https://doi.org/10.51253/pafmj.v75isuppl-3.12679.

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Objective: To determine the association of admission plateletcrit with in-hospital outcomes in non ST-elevation myocardial infarction (NSTEMI). Study Design: Analytical Cross-sectional study Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, Rawalpindi; from Nov 2023 to Apr 2024 Methodology: Using non-probability consecutive sampling, 270 patients were included in this study. ECG findings were noted. Patients were divided into three tertiles based upon plateletcrit value such as T1=lower than normal PCT value (<0.21), T2=normal PCT(0.21-0.22) and T3= higher than normal PCT value (>0.22). PCT values were obtained from complete blood count sent at the time of presentation to AFIC emergency using Mandray BC 6200 CBC analyzer available at the AFIC pathology laboratory. Results: The study included 270 patients, out of which 137(50.7%) were males and 133(49.3%) were females and median age was 62.00(55.00-70.00) years. T1, T2 and T3 had 71(26.3%), 34(12.6%) and 165(61.1%) patients, respectively. Significant frequency differences of hypertensive and hyperlipidemia patients, and in-hospital outcomes were found between tertiles (p<0.01). Plateletcrit value was identified as an independent predictor for in-hospital outcomes including coronary revascularization (OR=0.08, 95% CI: 0.04-1.58, p<0.01), cardiogenic shock (OR=0.24, 95% CI: 0.15-0.37, p<0.01) and mortality (OR=0.04, 95% CI: 0.02-0.11, p<0.01), when adjusted for covariates. Conclusion: Plateletcrit value is an important predictor of in-hospital outcomes in NSTEMI patients, particularly coronary revascularization, cardiogenic shock, and mortality.

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Chalise, Sanat, Nishant Acharya, and Sailesh B. Pradhan. "Correlation between Iron Parameters and Platelet Parameters in Iron Deficiency Anemia." Journal of Institute of Medicine Nepal 41, no. 3 (2019): 35–38. http://dx.doi.org/10.3126/jiom.v41i3.37362.

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Introduction Iron deficiency anemia is the most common type of anemia and is diagnosed by iron studies. Reactive thrombocytosis is usually seen in iron deficiency anemia. The objectives of the study is to correlate between iron parameters and platelet parameters in patient with iron deficiency anemia. MethodsThis was a cross-sectional study done in Department of Pathology at Kathmandu Medical College, Sinamangal between December 2018 to May 2019. Blood samples of 81 iron deficiency anemia patients were analysed to determine iron parameters and platelet parameters. SPSS version 20 was used to analyse the data. ResultsThrombocytosis was seen in 62 (76.5%) patient with iron deficiency anemia. Platelet count was negatively correlated with serum iron, percentage saturation and platelet distribution width (p˂0.001, for all) while positive correlation was obtained between platelet count and plateletcrit (p<0.05). Plateletcrit showed negative correlation with serum iron (p˂0.001) and platelet distribution width (p<0.05) while positive correlation was obtained with mean platelet volume, total iron binding capacity and platelet (p<0.05, for all). There was negative correlation between mean platelet volume and platelet count (p<0.001). Positive correlation was obtained between mean platelet volume and plateletcrit (p<0.05). Correlation was not found between mean platelet volume and iron parameters (p>0.05). Platelet distribution width showed negative correlation with total iron binding capacity, platelet (p˂0.001, for both), plateletcrit (p<0.05). ConclusionThrombocytosis is more commonly observed as compared to thrombocytopenia in patient with iron deficiency anemia. Serum iron and percentage saturation are the most important parameters affecting the platelet count.

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Introduction: Iron deficiency anemia is the most common type of anemia and is diagnosed by iron studies. Reactive thrombocytosis is usually seen in iron deficiency anemia. The objectives of the study is to correlate between iron parameters and platelet parameters in patient with iron deficiency anemia. Methods: This was a cross-sectional study done in Department of Pathology at Kathmandu Medical College, Sinamangal between December 2018 to May 2019. Blood samples of 81 iron deficiency anemia patients were analysed to determine iron parameters and platelet parameters. SPSS version 20 was used to analyse the data. Results: Thrombocytosis was seen in 62 (76.5%) patient with iron deficiency anemia. Platelet count was negatively correlated with serum iron, percentage saturation and platelet distribution width (p˂0.001, for all) while positive correlation was obtained between platelet count and plateletcrit (p<0.05). Plateletcrit showed negative correlation with serum iron (p˂0.001) and platelet distribution width (p<0.05) while positive correlation was obtained with mean platelet volume, total iron binding capacity and platelet (p<0.05, for all). There was negative correlation between mean platelet volume and platelet count (p<0.001). Positive correlation was obtained between mean platelet volume and plateletcrit (p<0.05). Correlation was not found between mean platelet volume and iron parameters (p>0.05). Platelet distribution width showed negative correlation with total iron binding capacity, platelet (p˂0.001, for both), plateletcrit (p<0.05). Conclusion: Thrombocytosis is more commonly observed as compared to thrombocytopenia in patient with iron deficiency anemia. Serum iron and percentage saturation are the most important parameters affecting the platelet count.

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Liu, Xiaoyan, Guanqun Yi, Guoyang Zhang, et al. "The relationship between platelet parameters and bacterial types in patients with bacteremia: A retrospective observational study." Journal of Infection in Developing Countries 19, no. 03 (2025): 381–90. https://doi.org/10.3855/jidc.20548.

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Objective: To analyze the relationship between platelet parameters and bacterial types in patients with bacteremia. Methodology: Data from 265 patients with positive blood bacterial cultures were collected. Clinical parameters and procalcitonin (PCT) were recorded. Results: In 265 patients with bacteremia, gram-negative (G-) bacteria accounted for 56% of cases, and gram-positive (G +) bacteria accounted for 44% of cases. In patients with bacteremia, white blood cell counts (WBC), neutrophil counts (NEUT), the percentage of neutrophils (NEUT%), and PCT were increased, and lymphocyte counts (LYM) and the percentage of lymphocytes (LYM%) were decreased. The differences in plateletcrit values, NEUT%, LYM%, and PCT between the G- and the G + bacteria group were significantly different. The cutoff values of PCT, platelet, plateletcrit, and NEUT% were 1.31 ng/mL, 211 × 109/L, 0.205%, and 87.41%, respectively. The incidence of thrombocytopenia was 12%. There was no significant difference in WBC, NEUT%, PCT, platelet, platelet nadir, and days of thrombocytopenia between the G- and the G + bacteria among patients with thrombocytopenia. Conclusions: Platelet, plateletcrit, NEUT%, and PCT are helpful for the early identification of G- and G + bacteria. The combination of PCT and hemogram parameters is more conducive to the early differential diagnosis of bacterial classification.

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Singhal, Priyamvada, Vishal Agarwal, Narayan S. Ingole, and Nitin Gangane. "Do platelet indices play a role in assessing severity of pre-eclampsia and eclampsia?" Journal of Pathology of Nepal 11, no. 2 (2021): 1790–95. http://dx.doi.org/10.3126/jpn.v11i2.31241.

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Background: Pre-eclampsia and eclampsia is a multisystem disorder affecting approximately 2-7% of all pregnancies and is a significant cause of maternal and fetal morbidity and mortality. Many hemostatic abnormalities have been reported in association with hypertensive disorder of pregnancy. We conducted this prospective case-control study to assess and analyze the platelet parameters in 3rd-trimester normotensives, pre-eclamptic, and eclamptic pregnant women. Materials and methods: This study was conducted in the hematology division of the Department of Pathology, in a rural population-based medical institute over 2 years. In all subjects (cases and controls) 2 ml of blood sample was collected in EDTA vials for platelet counts and platelet indices. The blood samples were run on an automated blood cell counter (Beckman coulter) within 2 hours of collection. The data obtained were tabulated and statistical analyses were performed. Results: The mean platelet count was significantly decreased in cases as compared to controls with increased frequency of thrombocytopenia associated with progression of the disease. Platelet indices, mean platelet volume, and platelet distribution width were increased, whereas the plateletcrit was decreased in cases as compared to the controls. However, the statistically significant difference was found only in platelet distribution width and plateletcrit. Conclusions: We concluded that platelet indices like platelet distribution width and plateletcrit can be useful along with platelet count in early detection of pre-eclampsia and eclampsia instead of relying on platelet count alone.

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Song, YoungHee, Jeong-Yeal Ahn, Soon Ho Park, et al. "Evaluation of Platelet Indices for Differential Diagnosis of Thrombocytosis by ADVIA 120." Blood 114, no. 22 (2009): 4472. http://dx.doi.org/10.1182/blood.v114.22.4472.4472.

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Abstract Abstract 4472 Background Because there is no single clinical or laboratory finding for the diagnosis of essential thrombocythemia (ET), a differential diagnosis of other myeloproliferative neoplasms or reactive thrombocytosis (RT) is always necessary. Developments in automated blood cell analysers can now measure various platelet indices and were used in this study to differentiate between ET and RT in patients with a platelet count of 600×103/μL or more. Method The subjects studied were 31 patients with ET and 224 patients with RT. The platelet counts, mean platelet volume (MPV), plateletcrit (PCT), platelet distribution width (PDW), mean platelet mass (MPM), mean platelet component concentration (MPC) and large platelets (LPLT) were measured by ADVIA 120 (Bayer Diagnostics, USA) and the sensitivity and specificity of the two groups were determined. Results In essential thrombocythemia, all parameters except MPC were higher than those of reactive thrombocytosis and were statistically significant. The sensitivity and specificity were 74.2% and 84.4% when the platelet count was more than 820×103/μL. The sensitivity and specificity were 80.6% and 80.0% when the plateletcrit was more than 0.63%. The sensitivity and specificity were 64.5% and 99.1%, respectively, when LPLT was more than 23×103/μL. Conclusion The platelet counts and platelet indices are important for the differential diagnosis of thrombocytosis. The comparison of the plateletcrit and LPLT is particularly useful when the platelet count is markedly increased. Disclosures: No relevant conflicts of interest to declare.

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Shanker, Swathy, and Niranjana Murthy B. "Plateletcrit - An important indicator of hypertension induced organ damage." Research Journal of Medical and Allied Health Sciences 3, no. 2 (2021): 1–5. http://dx.doi.org/10.46319/rjmahs.2020.v03i02.001.

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Ergelen, Mehmet, and Huseyin Uyarel. "Plateletcrit: A novel prognostic marker for acute coronary syndrome." International Journal of Cardiology 177, no. 1 (2014): 161. http://dx.doi.org/10.1016/j.ijcard.2014.09.054.

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Aynıoglu, Oner, Hatice Isık, Ahmet Sahbaz, Mehmet I. Harma, Metin Isık, and Furuzan Kokturk. "Can Plateletcrit be a Marker for Recurrent Pregnancy Loss?" Clinical and Applied Thrombosis/Hemostasis 22, no. 5 (2014): 447–52. http://dx.doi.org/10.1177/1076029614565882.

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Mangshetty, Roopa, Apurva A. B., and Shweta Harwal. "A study of relationship between various platelet indices and outcome of dengue fever in pediatric patients." International Journal of Contemporary Pediatrics 10, no. 8 (2023): 1216–21. http://dx.doi.org/10.18203/2349-3291.ijcp20232237.

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Background: The study analyzed clinical characteristics and platelet indices in 200 children (1 month to 15 years) diagnosed with dengue fever, admitted to affiliated hospitals. It aimed to explore the relationship between platelet indices and disease severity in pediatric patients of teaching hospitals affiliated with MRMC College with a confirmed diagnosis of dengue fever. Methods: In this study, the majority of patients were aged (10-15) years, with a small percentage (3.5%) being infants. Females accounted for 50% of the cases. Fever was the most common symptom, followed by headache, abdominal pain, and myalgia. Rash occurred in (14.5%) of cases. Among 200 cases, 80 exhibited warning signs, with varying positivity for NS1 and IgM. All patients required fluid therapy, and (77.5%) needed ICU care. Platelet count and Plateletcrit decreased initially but improved later, while PDW, MPV, and PLCR increased and then decreased. NS1-positive cases had lower platelet count and Plateletcrit but higher PLCR and MPV compared to IgM-positive cases. Results: The study found that lower platelet count and Plateletcrit, as well as higher mean platelet volume, were associated with more severe disease outcomes, including longer hospital stays, increased intensive care unit care, and higher fluid therapy requirements. However, there was no significant correlation between other platelet indices (PLCR and PDW) and disease severity indicators. Conclusions: In conclusion, this study provided valuable insights into the clinical features and platelet indices of patients with dengue fever. Understanding the relationship between these indices and disease severity can help in predicting the progression of the illness and improving patient management strategies.

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KC, Shiva Raj, S. Shrestha, G. KC, P. Gyawali, S. Dahal, and B. Maharjan. "Complete Blood Count Parameters in Arthritis." Nepal Medical College Journal 22, no. 3 (2020): 99–105. http://dx.doi.org/10.3126/nmcj.v22i3.32621.

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Osteoarthritis, rheumatoid arthritis, and gout are frequently encountered diseases in the orthopedic clinic. CRP is done to evaluate and monitor these disease processes. This study aimed to evaluate total leukocyte count with differential count, neutrophil/lymphocyte ratio, platelet, platelet/lymphocyte ratio, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit in patients with arthritis. This was a cross-sectional study conducted at KIST Medical College, Teaching Hospital from 15 Ashad 2075 to 14 Ashad 2076. The patient’s demographic data and laboratory findings: total leukocyte count, differential count, hemoglobin, platelet count, plateletcrit, mean platelet volume, platelet distribution width, and plateletcrit. CRP, ESR, RA factor/anti-CCP, and Uric acid tests were also performed. Among 67 patients, osteoarthritis was seen in 53 (79.1%), rheumatoid arthritis among 11(16.4%), and Gout among 3(4.5%). The ROC area under the curve was within acceptable limits for the neutrophil count, neutrophil/lymphocyte ratio, mean platelet volume, platelet distribution width. The sensitivity and specificity of the neutrophil count were 75% and 62% respectively (cut-off: 64.5%). Neutrophil/Lymphocyte ratio was increased and correlated with CRP (p-value: <0.001). PDW had a sensitivity of 90% and specificity of 83.0% (cut-off: 16.8 CV). For MPV, the sensitivity was 80% and specificity was 81% (cut-off: 9.1 fL). At 1.92 cut-off value, the sensitivity and specificity of neutrophil/lymphocyte ratio were 80.0% and 62.0% respectively. CBC parameters can provide an important clue to the treating physician, which helps to manage a patient with arthritis effectively. Neutrophil count, Neutrophil/Lymphocyte ratio, MPV, and PDW correlated with other inflammatory biomarkers and can be used to assess the patient with arthritis.

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Beyan, Cengiz, and Esin Beyan. "Plateletcrit values may not be higher in patients with vitiligo." Archives of Dermatological Research 313, no. 6 (2021): 499–500. http://dx.doi.org/10.1007/s00403-021-02191-5.

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Ji, Shuaifei, Xiaona Ning, Babo Zhang, Heng Shi, Zheng Liu, and Jie Zhang. "Platelet distribution width, platelet count, and plateletcrit in diabetic retinopathy." Medicine 98, no. 29 (2019): e16510. http://dx.doi.org/10.1097/md.0000000000016510.

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Beyan, Cengiz, and Esin Beyan. "Plateletcrit May Not be a Marker for Recurrent Pregnancy Loss." Clinical and Applied Thrombosis/Hemostasis 21, no. 6 (2015): 588–89. http://dx.doi.org/10.1177/1076029615579100.

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Coskun, ME, A. Alidris, MT Temel, S. Akbayram, and S. Hizli. "Plateletcrit: A possible biomarker of inflammation in hepatitis A infection." Nigerian Journal of Clinical Practice 22, no. 5 (2019): 727. http://dx.doi.org/10.4103/njcp.njcp_331_18.

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Reddy, Uma Maheswara, Aditya Khandekar, Sourya Acharya, Samarth Shukla, and Neema Acharya. "Study of Platelet Indices in Patients with Metabolic Syndrome." International Journal of Recent Surgical and Medical Sciences 05, no. 01 (2019): 010–14. http://dx.doi.org/10.1055/s-0039-1688542.

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Abstract Introduction Metabolic syndrome (MetS) is a combination of abdominal obesity, atherogenic dyslipidemia, elevated blood pressure, and elevated plasma glucose. MetS patients have higher chances of developing insulin resistance, visceral adiposity, atherogenic dyslipidemia, and thus coronary artery disease and stroke. Alteration of platelet indices in diabetes mellitus, atherosclerosis, and other proinflammatory states has been described in multiple studies. Thus, this study was carried out to assess platelet indices in MetS. Objectives This study was carried out to assess platelet indices in MetS. Methods A cross-sectional study was carried out at Acharya Vinoba Bhave Rural Hospital, a tertiary care center over a period of 2 months from June 1, 2018 to July 31, 2018. Fifty patients diagnosed as having MetS, and 50 healthy controls were chosen. Estimation of anthropometric parameters including waist circumference; measurement of blood pressure; biochemical parameters including lipid profile; and platelet indices including plateletcrit, mean platelet volume (MPV), and platelet distribution width (PDW) were carried out. Statistical Analysis Statistical analyses were carried out using inferential statistics, including chi-square test and Student's unpaired t-test, and software SPSS version 22.0 (IBM Corporation, Armonk, New York, United States) with GraphPad Prism version 6.0 (Informer Technologies, Inc. Los Angeles, California, United States) was used, with p < 0.05 being considered as significant. Results A statistically significant, positive correlation was found between the waist circumference, systolic blood pressure, serum triglyceride levels, and plateletcrit, with the MetS status of patients (p < 0.05). Conclusion This study revealed that MetS is a proinflammatory and prothrombotic state, characterized by alteration of platelet indices. Plateletcrit was shown to be a statistically significant biomarker along with other parameters such as waist circumference, systolic blood pressure, and serum triglyceride levels. Early detection and follow-up of patients using these markers can lead to an overall decline in morbidity and mortality owing to MetS.

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Shaviya, Nathan, Valentine Budambula, Mark K. Webale, and Tom Were. "Circulating Interferon-Gamma Levels Are Associated with Low Body Weight in Newly Diagnosed Kenyan Non-Substance Using Tuberculosis Individuals." Interdisciplinary Perspectives on Infectious Diseases 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/9415364.

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Although interferon-gamma, interleukin-10, and adiponectin are key immunopathogenesis mediators of tuberculosis, their association with clinical manifestations of early stage disease is inconclusive. We determined interferon-gamma, interleukin-10, and adiponectin levels in clinically and phenotypically well-characterised non-substance using new pulmonary tuberculosis patients (n=13) and controls (n=14) from Kenya. Interferon-gamma levels (P<0.0001) and interferon-gamma to interleukin-10 (P<0.001) and interferon-gamma to adiponectin (P=0.027) ratios were elevated in tuberculosis cases. Correlation analyses in tuberculosis cases showed associations of interferon-gamma levels with body weight (ρ=-0.849;P<0.0001), body mass index (ρ=0.664;P=0.013), hip girth (ρ=-0.579;P=0.038), and plateletcrit (ρ=0.605;P=0.028); interferon-gamma to interleukin-10 ratio with diastolic pressure (ρ=-0.729;P=0.005); and interferon-gamma to adiponectin ratio with body weight (ρ=-0.560;P=0.047), body mass index (ρ=-0.604;P=0.029), and plateletcrit (ρ=0.793;P=0.001). Taken together, our results suggest mild-inflammation in early stage infection characterised by upregulation of circulating interferon-gamma production in newly infected TB patients.

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Isık, H., O. Aynıoglu, A. Sahbaz, et al. "Can plateletcrit, an underestimated platelet parameter, be related with preterm labour?" Journal of Obstetrics and Gynaecology 35, no. 7 (2015): 676–80. http://dx.doi.org/10.3109/01443615.2015.1004530.

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Polat, H., M. T. Gulpinar, M. A. Sarıca, and C. Benlioglu. "Relationship between mean platelet volume, platelet distribution width, plateletcrit and varicocele." Andrologia 49, no. 1 (2016): e12594. http://dx.doi.org/10.1111/and.12594.

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Ozbalci, Demircan, Emine Guchan Alanoglu, Kamuran Yuceer, and Hande Nur Eroglu. "Plateletcrit as a prognostic marker in Hodgkin lymphoma: A pilot study." Journal of Surgery and Medicine 7, no. 1 (2023): 91–94. http://dx.doi.org/10.28982/josam.7634.

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Background/Aim: Hodgkin lymphoma (HL) is a lymphoproliferative malignancy associated with inflammation. Plateletcrit (PCT) is a mean platelet volume (MPV) and platelet count-derived marker that is useful for evaluating malignancies and inflammatory diseases. International Prognostic Score (IPS-7) and more recently, IPS-3, are two indices indicating the prognosis of patients; however, widespread and easy to interpret prognostic markers are still needed for HL evaluation. Very few studies evaluating the prognostic significance of platelet indices in HL have been published, so we aimed to show the relationship between PCT and other adverse prognostic factors in HL and evaluate whether PCT can be used as a prognostic marker in HL. Methods: After excluding patients with insufficient data, 75 patients diagnosed with HL and 150 healthy controls were retrospectively analyzed in this case-control study. Evaluation of relationship of PCT and adverse HL prognostic factors, such as age, gender, hemoglobin, leukocytes, lymphocytes (absolute value and percentage), albumin, Ann Arbor stage and B symptoms, IPS-3 and-7 prognostic scores and post-treatment relapse, and progression-free survival of the patients were studied. Results: Mean MPV values were significantly lower, mean platelet values were significantly higher inpatient group (all P<0.001). Patients with high sedimentation had significantly higher mean PCT than those without (P=0.031) and a moderately positive correlation between PCT and sedimentation were found (r=0.33, P<0.01). Mean PCT values after treatment significantly decreased compared to baseline levels (P<0.001). Conclusion: PCT may be useful as a prognostic marker in HL. Further studies were needed to evaluate the relationship between PCT and other prognostic factors, such as IPS-3 and -7.

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Rabbani, Aftab, Saqib Allah Dad, Ahsan Ayub, Bushra Adeel, Muhammad Azam, and Ayesha Masood. "Association between Platelet and Iron Parameters in Patients with Iron Deficiency Anemia." Pakistan Journal of Medical and Health Sciences 16, no. 2 (2022): 1002–3. http://dx.doi.org/10.53350/pjmhs221621002.

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Iron deficiency anemia is the most prevalent anemia type and is identified by the use of blood tests for iron levels. In iron deficiency anemia, reactive thrombocytosis is a common complication. The study's primary goal is to determine if there is a relationship between platelet and iron parameters in patients with iron deficient anemia. Place and Duration: This cross-sectional research was done among patients with iron deficiency anemia in the Department of Medicine and Pathology, Sharif Medical College, Lahore for one-year duration from January 2021 to December 2021. Method: This Observational research was conducted in the Department of Medicine and Pathology order to collect information. The platelet and iron parameters of 70 iron deficiency anemia patients were determined using blood samples taken from the patients. The data was analyzed with the help of SPSS version 20. Results: Patients with iron deficiency anemia were found to have thrombocytosis in 58 (82.9 percent) of the cases. When serum iron, percentage saturation, and platelet distribution were taken into consideration (all p0.001), platelet count was shown to be adversely connected to these variables, but a positive association was found between plateletcrit and platelet count (all p<0.05). There was a negative link between serum iron and plateletcrit (p<0.001) and PDW (p<0.05), but only a positive relationship was found with TIBC, mean platelet volume (p<0.05), and platelet (all p<0.05). There was a significant negative relationship between platelet count and mean platelet volume (p<0.001). Platelet and mean platelet volume correlated positively (p<0.05), while plateletcrit and mean platelet volume correlated negatively (p<0.05). Neither a correlation nor a non-correlation between iron parameters and mean platelet volume were discovered (p>0.05). Conclusion: When it comes to patients with iron deficient anemia, thrombocytosis is more prevalent than thrombocytopenia. The most critical factors impacting platelet count are serum iron and percentage saturation. Keywords: Hemoglobin, thrombocytosis and iron deficiency anemia.

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Tarasov, D. O., I. A. Lebedev, S. N. Suplotov, O. A. Nesterova, G. O. Tersenov, and T. E. Werbach. "Evaluation of platelet parameters in cerebral stroke in patients with HIV infection." Medical alphabet, no. 22 (September 29, 2021): 48–51. http://dx.doi.org/10.33667/2078-5631-2021-22-48-51.

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The article reﬂects the results of studying platelet parameters in HIV-positive patients with different types of stroke.Aim. To identify changes in laboratory parameters of a complete blood count which characterize the morphofunctional features of platelets in stroke among HIV-positive patients.Materials and methods. 110 HIV-positive patients who received treatment for stroke in hospitals of the Tyumen region were examined. The study of blood parameters was carried out at the analyzer Sysmex XE2100 (Japan). Blood sampling was carried out on the day of patients admission.The number of platelets and platelet indices were analyzed: MPV – mean platelet volume, PDW – platelet distribution width, PCT – plateletcrit and P-LCR – platelet large cell ratio. The control group consisted of 117 patients. The signifcance of the differences was determined at the twotailed signifcance level of p < 0.05.Results. There was a signifcant decrease in the number of platelets (p < 0.05), in average, on 34.3% among patients with hemorrhages and HIV infection. Among patients with ischemic stroke this decrease was less pronounced (p = 0.05). A signifcant decrease in plateletcrit was established among patients with intracranial hemorrhages, while it did not change signifcantly among patients with cerebral infarction. During evaluation of other platelet parameters, no signifcant differences were found between patients in experimental and control groups. The coeffcient of giant platelets prevailed by one and a half times in patients with hemorrhages associated with HIV infection, which turned out to be beyond the statistical signifcance.Conclusion. The presence of HIV infection leads to a more pronounced, reliable decrease in the number of platelets and plateletcrit among patients that have acute phase of the development of hemorrhagic stroke than in patients with cerebral infarction. The development of intracranial hemorrhage among HIV-positive patients is characterized by an increase of blood platelets with a high volume, the level of which increased by one and a half times being beyond the statistical signifcance and having as a leading mechanism the intensifcation of platelet formation in the bone marrow.

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Asmah, Richard Harry, Pomah Sackey, Patrick Adjei, et al. "Haematological Indices and Antioxidant Enzyme Activity in Ghanaian Stroke Patients." BioMed Research International 2022 (March 3, 2022): 1–8. http://dx.doi.org/10.1155/2022/1203120.

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Background. Stroke is a cardiovascular disorder causing mortality globally and long-lasting harm worldwide. The disease occurs when the blood flow to the brain is either interrupted or blocked. This disruption leads to the increase in reactive oxygen species (ROS), especially superoxide free radicals, resulting in oxidative stress. The superoxide radicals are removed by superoxide dismutase (SOD), a key antioxidant enzyme. In this work, we investigated haematological indices and superoxide dismutase enzyme activity in Ghanaian patients with stroke and healthy control participants. Materials and Methods. Thirty stroke patients attending a stroke clinic and thirty apparently healthy control participants were recruited into the study. Blood samples were collected to determine haematological indices and SOD enzyme activity in red blood cells. Results. The stroke patients had significantly high blood parameters such as white blood cell ( p < 0.001 ), neutrophil ( p < 0.001 ), lymphocyte ( p = 0.003 ), and eosinophil ( p < 0.001 ) comparing with study participants without stroke, who were the control group in the study. Other blood parameters such as red blood cell, ( p < 0.001 ), haemoglobin ( p < 0.001 ), and haematocrit ( p < 0.001 ) levels and mean cell haemoglobin concentration ( p = 0.030 ), platelet ( p = 0.010 ), and plateletcrit ( p = 0.027 ) were high in stroke patients comparing with study control participants and statistically significant. Blood lymphocyte levels observed in stroke patients correlated negatively and significantly with SOD activity levels. SOD activity levels were significantly lower in stroke patients compared with the control group ( p < 0.001 ). Low values of the antioxidant enzyme SOD activity levels, lymphocytes, and high values of plateletcrit were significant predictors of stroke. Conclusion. Haematological parameters such as WBC, lymphocyte, platelet levels, and red cell indices were significantly different in the stroke patients being studied. There was negative correlation between lymphocyte significantly with SOD activity and high oxidative stress in stroke patients compared with the control group. Lymphocytes and plateletcrit levels were also good predictors of the occurrence of stroke.

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Mutala, Abdul-Hakim, Kingsley Badu, Christian Owusu, et al. "Impact of malaria on haematological parameters of urban, peri-urban and rural residents in the Ashanti region of Ghana: a cross-sectional study." AAS Open Research 2 (June 5, 2020): 27. http://dx.doi.org/10.12688/aasopenres.12979.2.

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Background: We aimed at investigating the impact of malaria on the haematological parameters of residents from different demographic settlements in the Ashanti Region of Ghana. Malaria parasites trigger changes in certain haematological parameters, which may result in a number of clinical manifestations. Differences in demographic settlements, such as rural, peri-urban and urban settlements may also influence these changes, but this has not been extensively studied in Ghana. Methods: We conducted a hospital-based, cross-sectional study from January to December 2018 in three different settlements. A total of 598 participants were recruited. Blood smears were examined to detect and quantify malaria parasitaemia, while haematological parameters were measured using a haematology analyser. Results: Participants from the rural settlement had the highest malaria prevalence (21.3%) compared to the urban (11.8%) and peri-urban areas (13.3%); however, the peri-urban area had the highest median parasite density (568; IQR=190.0-1312.0). Age was significantly associated with the odds of malaria positivity (OR: 0.97; CI:0.96 — 0.99). When haematological parameters of the malaria-infected study participants were compared to the parameters of uninfected participants, red blood cell count (p=0.017), haemoglobin (p=0.0165), haematocrit (p=0.0015), mean corpuscular volume (p=0.0014), plateletcrit (p<0.0001) and platelet count (p<0.0001) were all significantly lower in the malaria infected group. In addition to age, haemoglobin and plateletcrit levels were also inversely correlated with the odds of testing positive for malaria, suggesting that children who were anaemic and/or thrombocytopaenic were likely to be infected. After fitting the data to a logistic regression model comprising the three variables, the model correctly categorised 78% of uninfected study participants, but only 50% of the malaria-positive participants. Conclusions: Study participants who were positive for malaria were younger and had low haemoglobin and plateletcrit levels compared to uninfected individuals. Further studies are needed to more precisely elucidate the relationship between malaria infection,demographic and haematological parameters.

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Mutala, Abdul-Hakim, Kingsley Badu, Christian Owusu, et al. "Impact of malaria on haematological parameters of urban, peri-urban and rural residents in the Ashanti region of Ghana: a cross-sectional study." AAS Open Research 2 (July 9, 2020): 27. http://dx.doi.org/10.12688/aasopenres.12979.3.

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Background: We aimed at investigating the impact of malaria on the haematological parameters of residents from different demographic settlements in the Ashanti Region of Ghana. Malaria parasites trigger changes in certain haematological parameters, which may result in a number of clinical manifestations. Differences in demographic settlements, such as rural, peri-urban and urban settlements may also influence these changes, but this has not been extensively studied in Ghana. Methods: We conducted a hospital-based, cross-sectional study from January to December 2018 in three different settlements. A total of 598 participants were recruited. Blood smears were examined to detect and quantify malaria parasitaemia, while haematological parameters were measured using a haematology analyser. Results: Participants from the rural settlement had the highest malaria prevalence (21.3%) compared to urban (11.8%) and peri-urban areas (13.3%); however, the peri-urban area had the highest median parasite density (568; IQR=190.0-1312.0). Age was significantly associated with the odds of malaria positivity (OR: 0.97; CI:0.96 — 0.99; p=4.96*10-4). When haematological parameters of the malaria-infected study participants were compared to the parameters of uninfected participants, red blood cell count (p=0.017), haemoglobin (p=0.0165), haematocrit (p=0.0015), mean corpuscular volume (p=0.0014), plateletcrit (p<0.0001) and platelet count (p<0.0001) were all significantly lower in the malaria infected group. In addition to age, haemoglobin and plateletcrit levels were also inversely correlated with the odds of testing positive for malaria, suggesting that children who were anaemic and/or thrombocytopaenic were likely to be infected. After fitting the data to a logistic regression model comprising the three variables, the model correctly categorised 78% of uninfected study participants, but only 50% of the malaria-positive participants. Conclusions: Study participants who were positive for malaria were younger and had low haemoglobin and plateletcrit levels compared to uninfected individuals. Further studies are needed to more precisely elucidate the relationship between malaria infection,demographic and haematological parameters.

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ALTUNOK, İbrahim, and Serdar ÖZDEMİR. "Akut Pankreatit Hastalarında Trombosit İndeksleri ile Uzamış Yatış Arasındaki İlişki: Retrospektif Gözlemsel Bir Çalışma." Journal of Contemporary Medicine 12, no. 5 (2022): 743–48. http://dx.doi.org/10.16899/jcm.1131462.

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Aim: To investigate relationship between platelet count, platelet mass index, mean platelet volume, platelet distribution width and plateletcrit and prolonged hospitalization in patients with acute pancreatitis. Material and Method: This study was conducted as a retrospective cohort study of all patients with acute pancreatitis from a tertiary level, academic emergency department between June 2017 and July 2021. Demographics, comorbidities, laboratory parameters, length of stay in the hospital and 30-day mortality information of the patients were recorded using computer-based data system of the hospital. Hospitalizations lasting longer than 7 days were considered as prolonged hospitalization. Results: 752 patients with a median of age of 58 years (25th-75th percentiles: 43.5-75) were included in the study. The median length of hospital stay of the enrolled patients was 4 days (25th-75th percentiles: 3-7). The hospitalization of 166 patients was prolonged, and the prolonged hospitalization rate was 22.1%. The univariate analysis for platelet indices showed that there was no statistically significant difference [Platelet count (p=0.543), mean platelet volume (p=0.656), plateletcrit (p=0.427), platelet distribution width (p=0.497), and platelet mass index (p=0.484)]. Conclusion: There is no clear relationship between platelet indices and prolonged hospitalization and they could not be predictors of prolonged hospitalization in patients with acute pancreatitis.

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Hamur, Hikmet, Kamuran Kalkan, Hakan Duman, et al. "Plateletcrit and Platelet Distribution Width as Independent Predictors of Coronary Artery Ectasia." Kosuyolu Heart Journal 19, no. 3 (2016): 173–78. http://dx.doi.org/10.5578/khj.20979.

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ÇOLAKOĞLU, EKREM ÇAĞATAY, and ALI EVREN HAYDARDEDEOĞLU. "Thrombocyte indices and plateletcrit in dogs with primary immune-mediated hemolytic anemia." Medycyna Weterynaryjna 75, no. 05 (2019): 6262–2019. http://dx.doi.org/10.21521/mw.6262.

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Primary immune-mediated hemolytic anemia (IMHA) is one of the most common autoimmune disorders in dogs. Platelet indices in dogs with IMHA have not been commonly used in daily clinical practice. The purpose of this study was to evaluate trombocyte indices, including platelet count (PLT), mean platelet volume (MPW), platelet size deviation width (PDW), and plateletcrit (PCT) in dogs with primary IMHA and to compare them with the corresponding values in a control series of healthy dogs. This study was performed on 21 dogs diagnosed with primary IMHA and 11 healthy dogs. The inclusion criteria were the presence of a positive Coombs’ test, true agglutination, anemia with HCT <35 %, hyperbilirubinemia, bilirubinuria, hemoglobinemia, hemoglobinuria, and spherocytosis. MPV and PDW were significantly higher in the dogs with IMHA compared to the reference population. No significant differences were found in PLT and PCT between the groups. The use of MPV and PDW values in evaluating the bone marrow response would be helpful in dogs with primary IMHA.

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Schwartz, D., L. Sharkey, P. J. Armstrong, C. Knudson, and J. Kelley. "Platelet Volume and Plateletcrit in Dogs with Presumed Primary Immune-Mediated Thrombocytopenia." Journal of Veterinary Internal Medicine 28, no. 5 (2014): 1575–79. http://dx.doi.org/10.1111/jvim.12405.

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Sahin, Sevim, Betul Diler Durgut, Beril Dilber, Elif Acar Arslan, Tulay Kamasak, and Ali Cansu. "Increased hemoglobin and plateletcrit levels indicating hemoconcentration in pediatric patients with migraine." Journal of Pediatric Neurosciences 15, no. 2 (2020): 99. http://dx.doi.org/10.4103/jpn.jpn_73_19.

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Rani, Varada Vidya, and Ravichandrer Balasundaram. "Study of platelet parameters in sick children." International Journal of Contemporary Pediatrics 8, no. 3 (2021): 522. http://dx.doi.org/10.18203/2349-3291.ijcp20210658.

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Background: Prediction of outcome of a patient plays a key role in the management of PICU. Studies have predicted that platelet parameters are novel predictors of mortality. Hence, present study was designed to assess the accuracy of platelet parameters (platelet count, MPV (mean platelet volume), PDW (platelet distribution width), PCT (Plateletcrit), MPV/PCT, PDW/Platelet count, MPV/platelet count in prediction of mortality and morbidity. Methods: Total 66 children requiring admission to PICU, were divided as sick (with sick score≥3) and non-sick (with sick score<3). Their platelet parameters were compared. Platelet parameters were further studied with respect to morbidity and mortality. Statistical analysis was done using SPSS 22 version software. Chi-square test was used as test of significance for qualitative data. Continuous data was represented as mean and standard deviation. Independent t test was used as test of significance to identify the mean difference between two quantitative variables. Results: Both groups were comparable in terms of age and gender. Significant difference in all platelet parameters were noted in between groups (p<0.001). Platelet parameters and their ratios were significant predictors of mortality and morbidity, with negative correlation to platelet count and plateletcrit (PCT), and positive correlation to the rest.Conclusions: Simple analysis of platelet indices at admission by haematology counter analysers could give us a great idea in predicting the mortality and morbidity of the children.

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Yang, Xue-Jiao, Le-Yang Zhang, Qing-Hua Ma, et al. "Platelet parameters in Chinese older adults with metabolic syndrome." Endocrine Connections 9, no. 7 (2020): 696–704. http://dx.doi.org/10.1530/ec-20-0209.

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Purpose: We aimed to examine the associations of platelet parameters with the presence of metabolic syndrome in community-dwelling older Chinese adults. Methods: Study sample was from the Weitang Geriatric Diseases Study, which included 4338 individuals aged 60 years or above. The mean age of the participants was 68 years. Metabolic syndrome was defined based on the Adult Treatment Panel III criteria. Platelet parameters were assessed using an automated hematology analyzer. Multiple logistic regression models were fitted to examine relationships between the platelet parameters and the presence of metabolic syndrome after adjusting for potential confounders. Results: The adjusted odds ratio (95% CI) of metabolic syndrome for the highest quartile of platelet parameters (platelet count, mean platelet volume, plateletcrit, platelet distribution width, platelet larger cell ratio) when compared to the lowest quartile were 1.32 (1.06, 1.64), 1.00 (0.81, 1.24), 1.37 (1.10, 1.71), 1.45 (1.14, 1.83), 1.11 (0.89, 1.39), respectively. Hypertension and diabetes modified the relationship between platelet distribution width and metabolic syndrome with the associations being significant in hypertensive and non-diabetic groups. The levels of platelet distribution width increased with the risk of metabolic syndrome in men but not in women. Conclusion: The levels of platelet count, plateletcrit and platelet distribution width increased in older adults with metabolic syndrome, suggesting that these parameters may be useful biomarkers for further risk appraisal of metabolic syndrome in aged population.

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Ustaoglu, Gülbahar, Emrah Erdal, and Mehmet İnanır. "Does periodontitis affect mean platelet volume(MPV) and plateletcrit (PCT) levels in healthy adults?" Revista da Associação Médica Brasileira 66, no. 2 (2020): 133–38. http://dx.doi.org/10.1590/1806-9282.66.2.133.

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SUMMARY OBJECTIVE Periodontitis may stimulate infectious and immune response and cause the development of atherogenesis, coronary heart disease, and myocardial infarction. The aim of this study was to compare the plateletcrit (PCT) and mean platelet volume (MPV) levels derived from complete blood count (CBC) tests in patients suffering from stage 3 periodontitis with those of healthy individuals without periodontal disease. METHODS The study included 57 patients (28 females and 29 males) with Stage 3 Periodontitis and 57 volunteering individuals (31 females and 26 males) who were periodontally healthy. The age of study participants ranged from 18 to 50 years. Their periodontal condition was investigated with probing depth (PD), clinical attachment level, bleeding on probing, and plaque index. Leukocyte (WBC) and erythrocyte count (RBC), hemoglobin (Hb) and hematocrit (HCT) levels, mean corpuscular volume (MCV) and red cell distribution width (RDW), thrombocyte count, mean platelet volume (MPV), plateletcrit (PCT ), and neutrophil and lymphocyte counts were evaluated based on the CBC test results of the study participants. RESULTS PCT, WBC, Neutrophil, and MPV values were found to be significantly higher in the periodontitis group (p<0.05). There were no significant differences in RBC counts, Hb, HCT, MCV, RDW, and platelet and lymphocyte counts between the two study groups (p>0.05). CONCLUSIONS PCT and MPV levels may be a more useful marker to determine an increased thrombotic state and inflammatory response in periodontal diseases.

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Hafeez, Ammara, Nasir ud Din Khattak, Samina Naeem, Helen Mary Robert, Shamaila Mohsin, and Amal Mahmood. "Platelet Indices as a Tool for Differentiation between Clonal Thrombocytosis and Reactive Thrombocytosis." Pakistan Armed Forces Medical Journal 73, SUPPL-1 (2023): S79–83. http://dx.doi.org/10.51253/pafmj.v73isuppl-1.6350.

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Objective: To determine the efficacy of platelet indices as a tool for differentiation between clonal thrombocytosis and reactive thrombocytosis. Study Design: Cross sectional study. Place and Duration of Study: Department of Pathology, Combined Military Hospital, Lahore Pakistan, from Nov 2019 to Oct 2020. Methodology: Fifty-six subjects were included in Reactive thrombocytosis group and 56 in Clonal thrombocytosis group. Fresh blood in EDTA anticoagulant was analyzed to determine complete blood counts and platelet parameters (Platelet distribution width, mean platelet volume, Platelet large cell ratio, Plateletcrit) using the automated hematological analyzer Sysmex KX-21. Results: Mean age of the patients was 45.76 years with a range of 17-75 years. Assessing the cause of reactive thrombocytosi revealed that 20(35.7%) was infection and 16(28.5%) was iron deficiency anemia. In clonal thrombocytosis group 21(37.5%) were diagnosed with Chronic myeloid leukemia, 13(23.2%) with Essential thrombocythemia and 14(25%) with Polycythemia rubera vera. Platelet indices were compared in clonal thrombocytosis group and the reactive thrombocytosis group. Mean platelet volume, Platelet large cell ratio and Plateletcrit were significantly higher in the clonal thrombocytosis group (p=0.001). Difference in Platelet distribution width was not found to be statistically significant in the two groups (p=0.07) Conclusion: Platelet indices were higher in the clonal thrombocytosis group. Along with platelet count, they can serve as an efficient and cost-effective method in differentiating between clonal and reactive thrombocytosis.

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Cikrikci Isik, Gulsah, Cansu Ozturk, Seref Kerem Corbacioglu, Selma Uysal Ramadan, and Yunsur Cevik. "Plateletcrit as a Determinant of Diffusion-Restricted Lesion Volume in Diffusion-Weighted Imaging." Cyprus Journal of Medical Sciences 6, no. 1 (2021): 50–53. http://dx.doi.org/10.5152/cjms.2021.2580.

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Gou, Bo, Hong Cao, Xinghua Cheng, Wei Shang, Mingqin Xu, and Wei Qian. "Prognostic value of mean platelet volume to plateletcrit ratio in patients with osteosarcoma." Cancer Management and Research Volume 11 (February 2019): 1615–21. http://dx.doi.org/10.2147/cmar.s193949.

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Wang, Jian, Juan Xia, Xiaomin Yan, et al. "Plateletcrit as a potential index for predicting liver fibrosis in chronic hepatitis B." Journal of Viral Hepatitis 27, no. 6 (2020): 602–9. http://dx.doi.org/10.1111/jvh.13264.

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