Relevant bibliographies by topics / Platelets count

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Platelets count'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Platelets count"

1

Hanson, SR, and SJ Slichter. "Platelet kinetics in patients with bone marrow hypoplasia: evidence for a fixed platelet requirement." Blood 66, no. 5 (1985): 1105–9. http://dx.doi.org/10.1182/blood.v66.5.1105.1105.

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Abstract We have studied 16 normal subjects and 27 patients with stable, untreated thrombocytopenia secondary to bone marrow failure and platelet counts ranging from 12,000 to 70,000/microL. Autologous platelets were labeled with 51Cr for measurement of mean platelet life span in the normal subjects and in 20 patients. Labeled donor cells were used in the remaining subjects. Platelet survival, as determined with both autologous and homologous platelets, correlated directly with platelet count in the thrombocytopenic patients. Platelet life span was only modestly reduced in patients having coun
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Hanson, SR, and SJ Slichter. "Platelet kinetics in patients with bone marrow hypoplasia: evidence for a fixed platelet requirement." Blood 66, no. 5 (1985): 1105–9. http://dx.doi.org/10.1182/blood.v66.5.1105.bloodjournal6651105.

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We have studied 16 normal subjects and 27 patients with stable, untreated thrombocytopenia secondary to bone marrow failure and platelet counts ranging from 12,000 to 70,000/microL. Autologous platelets were labeled with 51Cr for measurement of mean platelet life span in the normal subjects and in 20 patients. Labeled donor cells were used in the remaining subjects. Platelet survival, as determined with both autologous and homologous platelets, correlated directly with platelet count in the thrombocytopenic patients. Platelet life span was only modestly reduced in patients having counts in the
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Goodnough, Lawrence T., David J. Kuter, Jeffrey McCullough, et al. "Prophylactic platelet transfusions from healthy apheresis platelet donors undergoing treatment with thrombopoietin." Blood 98, no. 5 (2001): 1346–51. http://dx.doi.org/10.1182/blood.v98.5.1346.

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Many patients receiving dose-intensive chemotherapy acquire thrombocytopenia and need platelet transfusions. A study was conducted to determine whether platelets harvested from healthy donors treated with thrombopoietin could provide larger increases in platelet counts and thereby delay time to next platelet transfusion compared to routinely available platelets given to thrombocytopenic patients. Community platelet donors received either 1 or 3 μg/kg pegylated recombinant human megakaryocyte growth and development factor (PEG-rHuMGDF) or placebo and then donated platelets 10 to 15 days later.
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Octavira, Imanta Alifia, Agrijanti Agrijanti, Lalu Srigede, and Siti Zaetun. "Perbandingan Jumlah Trombosit pada Pasien COVID-19 dengan Kadar Glukosa yang Berbeda." Jurnal Kesehatan Andalas 11, no. 2 (2022): 95. http://dx.doi.org/10.25077/jka.v11i2.2000.

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Hyperglycemia has increased arachidonic acid thromboxane which is an effective ingredient in platelet activation. Thrombocytopenia in COVID-19 patients occurs through a variety of mechanisms, such as uncontrolled production of cytokines destroying bone marrow progenitor cells, direct inhibition of hematopoiesis viral infection of the bone marrow, increase in autoantibodies and immune complexes that cause platelet destruction, and lung injury that causes platelet aggregation and consumption of platelets so that platelets in the circulation are reduced. Objectives: To analyzed the ratio of plate
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Sallmon, Hannes, Boris Metze, Petra Koehne, et al. "Mature and immature platelets during the first week after birth and incidence of patent ductus arteriosus." Cardiology in the Young 30, no. 6 (2020): 769–73. http://dx.doi.org/10.1017/s1047951120000943.

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AbstractBackground:Thrombocytopenia is a risk factor for patent ductus arteriosus. Immature and mature platelets exhibit distinct haemostatic properties; however, whether platelet maturity plays a role in postnatal, ductus arteriosus closure is unknown.Methods:In this observational study, counts of immature and mature platelets (=total platelet count − immature platelet count) were assessed on days 1, 3, and 7 of life in very low birth weight infants (<1500 g birth weight). We performed echocardiographic screening for haemodynamically significant patent ductus arteriosus on day 7.Results:Co
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Tucker, Erik I., Ulla M. Marzec, Sawan Hurst, András Gruber, and Stephen R. Hanson. "Moderate Pharmacological Platelet Count Reduction Limits Thrombus Formation without Hemostatic Impairment in Primates." Blood 112, no. 11 (2008): 1033. http://dx.doi.org/10.1182/blood.v112.11.1033.1033.

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Abstract Despite the established contribution of platelets to thrombotic cardiovascular disorders, documented in part by the effectiveness of platelet function inhibitors and the increased risk of thrombosis associated with high normal and supranormal platelet counts, relationships between circulating platelet count and thrombotic events remain largely undefined. Since the initiation and propagation of arterial, platelet-dependent thrombus must depend upon platelet count, albeit in a manner that could be nonlinear, we hypothesized that reducing platelet count within the normal range would prod
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Prasetya, Hieronymus Rayi, Maria Irena Dentri, and Sistiyono Sistiyono. "Perbedaan Hitung Jumlah Trombosit Menggunakan Darah Vena dan Darah Kapiler." Journal of Health 3, no. 2 (2016): 81. http://dx.doi.org/10.30590/vol3-no2-p81-84.

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Background: Platelets play a role in hemostasis which is the body's mechanisms to prevent and stop the bleeding. Platelets participate in the effort to close the wound, so that the body does not experience a loss of blood and protected from foreign cells. Examination of the platelet count is very important in the diagnosis of diseases, one of which is the diagnosis of dengue hemorrhagic fever (DHF). Examination of blood counts, especially platelets in clinical laboratories causes blood samples in use are not always the venous blood but could use capillary blood. Capillary blood samples are use
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Hoffmann, Johannes J. M. L., Nicole M. A. van den Broek, and Joyce Curvers. "Reference Intervals of Reticulated Platelets and Other Platelet Parameters and Their Associations." Archives of Pathology & Laboratory Medicine 137, no. 11 (2013): 1635–40. http://dx.doi.org/10.5858/arpa.2012-0624-oa.

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Context.—Reticulated platelets are platelets recently released from the bone marrow, and they can serve as a noninvasive indicator of recent megakaryopoietic activity. Widespread clinical use has been hampered by laborious methods and lack of standardization. Recently, a fully automated method was released on the Abbott CELL-DYN Sapphire hematology analyzer. Objective.—To establish reference ranges for reticulated platelets. Secondary aims were to investigate associations between reticulated platelets and other platelet parameters like mean platelet volume, plateletcrit, and platelet distribut
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Shiwangi, Chhanwal, Joshi Jigyasu, Rajak Vijay, and Nishu. "Changes in Platelet Parameters in Conditions of Leucocytosis." International Journal of Pharmaceutical and Clinical Research 16, no. 8 (2024): 981–83. https://doi.org/10.5281/zenodo.13620627.

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<strong>Background:&nbsp;</strong>Platelets are primarily concerned with haemostatic function but there are accumulating evidences to suggest their role in the pathophysiology of different clinical conditions that can be correlated with platelet parameters to some extent. This study was aimed to find out the relationship between WBC count in conditions of leucocytosis and platelet count and platelet parameters namely mean platelet volume, platelet distribution width and plateletcrit.&nbsp;<strong>Method:&nbsp;</strong>Complete blood count records of total 1000 cases were evaluated dividing the
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Speer, Oliver, Markus Schmugge, Imane Azzouzi, Margaret L. Rand, and Sabine Kroiss. "Apoptosis in Platelets from Pediatric Patients with Acute Immune Thrombocytopenic Purpura (ITP) Is Ameliorated by IV Ig." Blood 112, no. 11 (2008): 3417. http://dx.doi.org/10.1182/blood.v112.11.3417.3417.

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Abstract Interaction of auto-antibodies with platelet surface glycoproteins (GP) has been implicated in the accelerated clearance of platelets in ITP. It was recently shown, using a murine model, that the ITP induced by injection of anti-GPIIb is associated with apoptotic-like processes in platelets. These apoptotic-like processes in platelets were similar to those observed during apoptosis in nucleated cells: activation of caspase-3 (aCASP3), loss of mitochondrial inner transmembrane potential and externalisation of phosphatidylserine (PS). Administration of IVIg, that ameliorates the ITP in
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Dissertations / Theses on the topic "Platelets count"

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Ekbom, Lisa H. "Evaluation of the ADVIA®60 on highvalue platelets." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6149.

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<p>Platelets are the smallest cells in the blood. They are formed in the bone-marrow and are important for the blood coagulation. Platelet tranfusions are given to patients propyhlactically before an operation but also in therapeutical purpose in connection with bleeding. It’s importent that the quality controls of the platelet concentrates are reliable.</p><p>ADVIA®60 (Bayer HealthCare) is a fully automated cell counter which uses impedance principle to count platelets in blood samples. The purpose of the study was to evaluate this new instrument for use in the blood bank of Akademiska Sjukhu
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Corbett, Eric J. "Effects of Oral L-arginine Supplementation on Platelet Count and Maximal Oxygen Consumption in Healthy Males." University of Akron / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=akron1239596277.

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Mitander, Maria. "Evaluation of platelet parameters from Advia 2120 and Sysmex XT-2000iV in samples from dogs, horses and cats." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9260.

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<p>Haematology instruments using optical and fluorescence techniques have improved the platelet count in domestic animals. There are still some difficulties present, especially when counting cat thrombocytes due to their ability to aggregate and the occurrence of large platelets.</p><p>The objective of this study was to evaluate and compare the platelet count, mean platelet volume and platelet crit in dogs, horses and cats on Advia 2120 and Sysmex XT-2000iV.</p><p>Fresh blood samples from 64 dogs, 40 horses and 39 cats with various medical conditions were analysed on both instruments. Manual b
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Hlavac, Nicole Regina Capacchi. "Avaliação de parâmetros plaquetários em cães saudáveis: efeitos da temperatura, tempo e tipo de anticoagulante." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/49946.

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A contagem de plaquetas é um exame de rotina utilizado no auxilío do diagnóstico de diversos distúrbios hemostáticos, além de ser usada no monitoramento de pacientes, portanto existe a necessidade de obter parâmetros fidedignos para assegurar a existência de plaquetopenia ou plaquetose e alterações morfológicas destas células. A comum ocorrência de agregação plaquetária “in vitro” dificulta a análises destes parâmetros, evento devido ao uso incorreto da metodologia de coleta, armazenamento inadequado da amostra, assim como o uso incorreto do anticoagulante. O diagnóstico errôneo de plaquetopen
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Istrefi, Linda. "EN JÄMFÖRELSESTUDIE AV PLAST- OCH GLASHEMOCYTOMETRAR FÖR BERÄKNING AV BLODCELLER I VENÖST OCH KAPILLÄRT HELBLOD." Thesis, Malmö högskola, Fakulteten för hälsa och samhälle (HS), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-26966.

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Hematology-instruments that analyze blood cells can at specific casesbe followed by manual counting with a hemocytometer. The plastic hemocytometer which has a fixed coverslip and is assigned for disposable use, appears to reduce the problems arising from the use of the traditional glass hemocytometer, for instance coverslip-application difficulty and dust particles. Capillary whole blood sampling may be useful for patients at the emergency department and in addition, a smaller volume of blood is taken compared to venous blood sampling. This study will focus on the platelet- and leukocyte coun
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Puertas, Monica A. "Statistical and Prognostic Modeling of Clinical Outcomes with Complex Physiologic Data." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5106.

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Laboratory tests are a primary resource for diagnosing patient diseases. However, physicians often make decisions based on a single laboratory result and have a limited perspective of the role of commonly-measured parameters in enhancing the diagnostic process. By providing a dynamic patient profile, the diagnosis could be more accurate and timely, allowing physicians to anticipate changes in the recovery trajectory and intervene more effectively. The assessment and monitoring of the circulatory system is essential for patients in intensive care units (ICU). One component of this system is the
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Karlsson, Jessica. "Sample cradle prevents pre-analytic error on platelet counts but is not essential for hemoglobin measurement and prothrombin time." Thesis, Uppsala universitet, Institutionen för medicinsk biokemi och mikrobiologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-182146.

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Introduction: It is recommended to place all the vacuum tubes directly on a sample cradle after vein puncture to prevent analytic error. This recommendation is not always easy to follow because the samples are taken by different professionals under different situations.  The three most common analyses, platelets count, haemoglobin and prothrombin time were tested.  Therefore, it was interesting to compare results from the three most common analyses with or without sample cradle, to evaluate the influence of this step on the result. Methods: Three analyses were preformed, using blood from 50 di
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Santander, Mercado Alcides Ricardo. "Identification of Patient Recovery Patterns after Cardiovascular Surgery Based on Laboratory Tests Results." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3332.

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In this dissertation is proposed a methodology to identify patient's recovery patterns after cardiovascular surgery based on laboratory tests results. The main purpose is to enhance the understanding of the manifestations of postsurgical complications in patients who underwent cardiovascular surgery. The analysis of patients' recovery process is based on the relationship between plasma calcium, ionized calcium and platelet count over time. Laboratory results from the James A. Haley Veterans' Hospital databases, related to patients admitted to the Surgical Intensive Care Unit (SICU) after cardi
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Morowski, Martina [Verfasser], Bernhard Gutachter] Nieswandt, Thomas [Gutachter] [Dandekar, and Alma [Gutachter] Zernecke-Madsen. "Relevance of platelet count and ITAM-signalling pathway in murine models of haemostasis, thrombosis and thrombo-inflammation / Martina Morowski. Gutachter: Bernhard Nieswandt ; Thomas Dandekar ; Alma Zernecke-Madsen." Würzburg : Universität Würzburg, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-99193.

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Morowski, Martina Verfasser], Bernhard [Gutachter] Nieswandt, Thomas [Gutachter] [Dandekar, and Alma [Gutachter] Zernecke-Madsen. "Relevance of platelet count and ITAM-signalling pathway in murine models of haemostasis, thrombosis and thrombo-inflammation / Martina Morowski. Gutachter: Bernhard Nieswandt ; Thomas Dandekar ; Alma Zernecke-Madsen." Würzburg : Universität Würzburg, 2014. http://d-nb.info/1109749910/34.

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Books on the topic "Platelets count"

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Benoit, Elna. Understanding the complete blood count: The white blood cells : red blood cells, white blood cells or platelets. Concept Media, 2006.

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Benoit, Elna. Understanding the complete blood count: The red blood cells : red blood cells, white blood cells or platelets. Concept Media, 2006.

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Albert, Tyler J., and Erik R. Swenson. The blood cells and blood count. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0265.

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Blood is a dynamic fluid consisting of cellular and plasma components undergoing constant regeneration and recycling. Like most physiological systems, the concentrations of these components are tightly regulated within narrow limits under normal conditions. In the critically-ill population, however, haematological abnormalities frequently occur and are largely due to non-haematological single- or multiple-organ pathology. Haematopoiesis originates from the pluripotent stem cell, which undergoes replication, proliferation, and differentiation, giving rise to cells of the erythroid, myeloid, and
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Kuiper, Gerhardus J. A. J. M., and Hugo ten Cate. Coagulation monitoring. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0266.

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Haemostasis is a dynamic process to stop bleeding after vessel wall damage. Platelets form a platelet plug via activation, adherence, and aggregation processes. The coagulation proteins are activated one-by-one, cascading towards fibrin polymerization, a process controlled by thrombin generation. Fibrinolysis is the process responsible for fibrin mesh degradation, which is also controlled by thrombin. Besides procoagulant proteins, anticoagulant proteins maintain a balance in the haemostatic system. Measuring platelet count and function can be done as part of the monitoring of haemostasis, whi
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Okeke, Peter. Platelet Count and Indices of Mean Platelet Volume, Platelet Distribution Width and Platelet Large Cell Ratio - Is There Any Sex Difference? GRIN Verlag GmbH, 2012.

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Provan, Drew, Trevor Baglin, Inderjeet Dokal, and Johannes de Vos. Clinical approach. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199683307.003.0001.

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History taking in patients with haematological disease - Physical examination - Splenomegaly - Lymphadenopathy - Unexplained anaemia - Patient with elevated haemoglobin - Elevated white blood cell (WBC) count - Reduced WBC count - Elevated platelet count - Reduced platelet count - Easy bruising - Recurrent thromboembolism - Pathological fracture - Raised ESR - Serum or urine paraprotein - Anaemia in pregnancy - Thrombocytopenia in pregnancy - Prolonged bleeding after surgery - Positive sickle test (HbS solubility test)
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Provan, Drew, Trevor Baglin, Inderjeet Dokal, Johannes de Vos, and Hassan Al-Sader. Clinical approach. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199683307.003.0001_update_001.

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History taking in patients with haematological disease - Physical examination - Splenomegaly - Lymphadenopathy - Unexplained anaemia - Patient with elevated haemoglobin - Elevated white blood cell (WBC) count - Reduced WBC count - Elevated platelet count - Reduced platelet count - Easy bruising - Recurrent thromboembolism - Pathological fracture - Raised ESR - Serum or urine paraprotein - Anaemia in pregnancy - Thrombocytopenia in pregnancy - Prolonged bleeding after surgery - Positive sickle test (HbS solubility test)
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Turner, Neil, and Bertrand Knebelmann. MYH9 and renal disease. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0342_update_001.

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MYH9 encodes one of three heavy chain isoforms for the non-muscle myosin II (NM II) molecule. NM II is involved in cell structure and shape and motility. Myosin II is very widely expressed but MYH9 is highly expressed in podocytes. MYH9 diseases are characterized by various combinations of autosomal dominant progressive, proteinuric renal disease, giant platelets with low platelet counts, progressive sensorineural hearing impairment, granulocyte inclusions, and in some patients also cataracts. Although the eponyms Epstein and Fechtner have been given to MYH9 renal syndromes, there is a spectru
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Luna, Dotty. Coloring Book - You Will Get Better - Low Platelet Count. Independently Published, 2021.

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Kothari, Jaimal, and Marie Scully. Thrombocytopenia in the critically ill. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0272.

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Thrombocytopenia is an extremely common finding in patients in intensive care. This can lead to serious morbidity and mortality from bleeding, and also uncertainty with regards to how to assess this risk in the wider context of the underlying pathology, which may be multifactorial, when specific blood products should be transfused, and the associated risks of carrying out interventional procedures. Haemodilution, platelet consumption, increased platelet destruction, reduced production, and increased sequestration are the main mechanisms that account for thrombocytopenia, and in the ICU setting
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Book chapters on the topic "Platelets count"

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Aramendi, Ignacio, Martín Angulo, and Gastón Burghi. "Blood Count Profiles as Biomarkers in Burns: Red Cells, Platelets, and Beyond." In Biomarkers in Trauma, Injury and Critical Care. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-07395-3_19.

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Valcárcel, David, Isabel Sánchez-Ortega, and Anna Sureda. "Graft Failure." In The EBMT Handbook. Springer International Publishing, 2024. http://dx.doi.org/10.1007/978-3-031-44080-9_41.

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AbstractThe current definition for hematological recovery includes neutrophil recovery, defined as the first of three consecutive days with an absolute neutrophil count ≥0.5 × 109/L and platelet recovery which is defined as a platelet count of ≥20 × 109/L in the absence of platelet transfusion for 7 consecutive days.
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Peterson-Layne, Cathleen, and Beth R. Burton. "Platelet Count and Neuraxial Anesthesia." In Transfusion Management of the Obstetrical Patient. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-77140-3_10.

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Skoczyński, Szymon, Damian Krzyżak, Aleksandra Studnicka, et al. "Chronic Obstructive Pulmonary Disease and Platelet Count." In Advances in Pulmonary Medicine: Research and Innovations. Springer International Publishing, 2019. http://dx.doi.org/10.1007/5584_2019_379.

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Mascaretti, Luca G., and Paola Pradella. "The Critically Ill Patient with Abnormal Platelet Count." In Hematologic Problems in the Critically Ill. Springer Milan, 2014. http://dx.doi.org/10.1007/978-88-470-5301-4_6.

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Baryshnikova, Ekaterina. "COVID-19 Associated Coagulopathy: Platelet Count and Function." In The Coagulation Labyrinth of Covid-19. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-82938-4_6.

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Zandecki, Marc, Franck Genevieve, Jérémie Gérard, and Alban Godon. "Spurious Counts and Spurious Results on Hematology Analyzers: Platelets." In Laboratory Hematology Practice. Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781444398595.ch7.

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Nabila, Nabila, Rahma Yuantari, and Ety Sari Handayani. "The Effect of Diabetes Mellitus’s Duration on Platelet Count and Mean Platelet Volume’s Rat Stroke Model." In Proceedings of the 3rd International Conference on Cardiovascular Diseases (ICCvD 2021). Atlantis Press International BV, 2022. http://dx.doi.org/10.2991/978-94-6463-048-0_2.

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Damodaran, Senthilkumar, and Spero R. Cataland. "Excessive Bleeding with Normal Prothrombin Time, Partial Thromboplastin Time, and Platelet Count." In The Coagulation Consult. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-9560-4_6.

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Ruban, S., Mohammed Moosa Jabeer, and Sanjeev Rai. "Daily Platelet Count Prediction in Treating Dengue Patients Using Deep Learning Algorithm." In Lecture Notes in Electrical Engineering. Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-7633-1_38.

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Conference papers on the topic "Platelets count"

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Slichter, Sherrill J. "PATHOPHYSIOLOGY OF THROMBOCYTOPENIA AND RESULTANT CLINICAL INDICATIONS FOR PLATELET TRANSFUSION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643996.

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Careful evaluation of platelet survival data in normal individuals and patients with thrombocytopeniasecondary to marrow aplasia has demonstrated that platelets are lost from circulation by two mechanisms a fixed fraction of platelets, amounting to approxi mately 7,100 platelets/ul/day, are lost randomly while the remaining platelets are removed by senescent mechanisms. At platelet counts of &lt;100,000/ul, platelet survival becomes progressively shorter as the fixed platelet loss becomes a proportionately greater fraction of the circulating platelets. Thus, there is a direct relationship betw
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Yamazaki, H., K. Tanoue, K. Kuroiwa, H. Suzuki, M. Shibayama, and Y. Mano. "ACQUIRED STORAGE POOL DISEASE IN DECOMPRESSION SICKNESS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644563.

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The presence of hemostatic abnormalities has been reported in decompression sickness. It is suggested that platelets recognize air bubbles in the blood stream as a foreign surface and adhere to them with ensuing platelet aggregation. It is important to determine if consumption of platelets occurs in vivo to understand a role of platelets in the genesis of decompression sickness. To analyse the problem, platelet behavior was studied in 34 rabbits with decompression sickness which was brought about by the exposure to 6 ATA (atmospheres absolute) for 40 min followed by rapid decompression. All ra
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Dalby Kristensen, S., K. M. Roberts, and J. F. Martin. "INCREASE IN MEGAKARYOCYTE SIZE AND PLOIUY PRECEDES ACCELERATION OF ATHEROGENESIS IN THE HYPERCHOLESTEROLAEMIC RABBIT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643412.

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Platelet derived growth factor(s) probably synthesized by the megakaryocyte are important in atherogenesis. In a pilot study destruction of the circulating platelets was induced by injection of goat serum containing a specific platelet antibody (APS) to rabbits fed a high cholesterol diet (2g per day) for 12 weeks. Seven days after APS the percentage of atheroma in the aorta measured by planimetry was increased in these animals compared to control animals on the same diet that had been injected with goat serum (GS) 7 days before. In a new study 15 pairs of male litter mate rabbits on high chol
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Ikeda, Y., M. Murata, Y. Araki, et al. "BINDING OF FIBRINOGEN TO PLATELET GLYCOPROTEIN (GP) IIb/IIIa IS CRUCIAL FOR SHEAR-INDUCED PLATELET AGGREGATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643527.

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It is well known that human platelets can aggregate in vitro under certain shear stress without adding aggregating inducers. However, the mechanism of this shear-induced platelet aggregation has not been clarified yet. In this paper, we have investigated the role of fibrinogen and GP IIb/IIIa in shear-induced platelet aggregation. Citrated human platelet-rich plasma (PRP) was subjected to controlled shear stress levels in a polycarbonate cone and plate viscometer at 37°C for 2 minutes. After shearing the particle count was measured by an electronic particle counter. Particles with sizes from 3
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Badenhorst, P. N., H. F. Kotze, A. duP Heyns, M. G. Lotter, P. Wessels, and J. P. Roodt. "THE EFFECT OF INTRAVENOUS IMMUNOGLOBULIN ON PLATELET KINETICS IN CHRONIC IMMUNE THROMBOCYTOPAENIC PURPURA (ITP)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644585.

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Most patients with ITP respond to high doses of intravenous immunoglobulin (IVIg) with a transient increase in platelet count. The effect of IVIg on platelet kinetics was studied in 5 patients with chronic ITP. Autologous platelets were labelled with In-111 and mean platelet lifespan (MPLS) calculated; in vivo distribution and sites of platelet sequestration were determined with a scintillation camera and computer assisted image analysis. The studies were performed before and after treatment with 2 g/kg Sandoglobulin. Two groups of patients were identified: those with a splenic platelet seques
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Murphy, S. "STORAGE OF PLATELETS FOR TRANSFUSION - CURRENT METHODS AND PROBLEMS TO BE SOLVED." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643999.

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In the 1970's, when platelet concentrates (PC) were stored in "first generation" plastic containers at 22°C, many showed a fall in pH.In vivo viability was well maintained as pH fell from the starting level, 7.1, to 6.2 but was progressively lost below thatlevel. pH after a storage interval correlated with the platelet count in the PC, the higher the count, the lower the pH after storage. Since 30-50% of PC might have pH below 6.2 after 3 days of storage, shelflife was severely limited.We now have "second generation" containers which allow storage for 7 days without significant fall in pH.Supe
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Horellou, M. H., C. Capelle, T. Lecompte, et al. "PSEUDO-THROMBOCYTOPENIA ASSOCIATED WITH AN ANTICOAGULANT INDEPENDENT IgM PLATELET AGGLUTININ IN A PATIENT WITH PROLONGED BLEEDING TIME." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643975.

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An original observation of platelet agglutination was found in a 63 y.o. man during 5 years following, without spontaneous bleeding. Low platelet counts (10 × 109/liter) and large agglutinates were observed on blood specimens collected into EDTA (1 to 15 mg/ml whole blood WB), citrate (1/10 volume citrate 0.11 M), sodium heparin (100 units/ml WB), citrate plus acetyl salicylic acid (5 to 100 mg/ml WB), citrate plus prostacyclin (Upjohn 10−5 to 10−6 M)? and buffering anticoagulant (0.8 M citrate, pH 4.65). Low platelet count and large agglutinates were also observed in capillary blood obtained
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Mclaren, M., C. Shiach, B. Gibson, J. Pollock, G. D. O. Lowe, and C. D. Forbes. "THROMBOXANE AND PROSTACYCLIN GENERATION IN CHILDREN UNDERGOING CARDIAC BYPASS SURGERY." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643041.

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Children undergoing surgery involving cardiac bypass frequently have problems with post-operative bleeding, more so than children having the same length of surgery but without cardiac bypass. Although the platelet count is known to fall during bypass surgery it also falls in otter groups of surgical patients inwhom post-operative bleeding is nota problem. The passage of blood through the bypass machine may cause damage to the platelets which may therefore be functionally abnormal after surgery and thus promote bleeding. We studied eight patients undergoing cardiac bypass surgery aged between 4
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Waters, A. H., R. Ireland, R. S. Mibashan, et al. "FETAL PLATELET TRASFUSIONS IN THE MANAGEMENT OF ALLOIMMUNE THROMBOCYTOPENIA." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643977.

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Intracranial haemorrhage is the most serious complication of alloimmune neonatal thrombocytopenia (ANT). It has generally been assumed that this occurs during delivery, but evidence is accumulating that intracranial haemorrhage may have already occurred in utero. Management of the pregnancy at risk is therefore more exacting, and it has been suggested that intrauterine platelet transfusions may be of benefit (Daffos et al, Lancet, Li, 632. 1984). We have used this approach in two pregnancies in PlA1 negative mothers with PlA1 positive fetuses affected by ANT. Both were second pregnancies, the
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Scharf, R. E., A. Wehmeier, and W. Schneider. "REDUCED PLATELET THROMBOXANE FORMATION IN ACUTE THROMBOTIC THROMBOCYTOPENIC PURPURA (TP): EVIDENCE FOR AN ABNORMAL PLATELET POPULATION WITH A TRANSIENT CYCLOOXYGENASE DEFECT." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644588.

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We have recently shown that alpha-granule-depleted platelets circulate in acute TTP. These platelets are hemostatically defective due to partial loss of granular constituents and/or metabolic abnormalities. To further evaluate morphometric and metabolic changes of "exhausted" platelets, we studied their volume distribution and thromboxane A2 (TXA2) formation in a 35-year-old patient with primary TTP. Platelet volume distribution in whole blood was determined by the impedance method using citrate (0.38%)/glutaraldehyde (0.125%) as anticoagulant. TXB2 production was measured radioimmunologically
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Reports on the topic "Platelets count"

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Li, Rongyang, Zheng Ma, and Jianhao Qiu. Prognostic and clinicopathological significance of pretreatment systemic immune-inflammation index in esophageal cancer: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.8.0024.

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Review question / Objective: We performed this systematic review and meta-analysis to investigate the prognostic value of pretreatment systemic immune-inflammation index (SII) in esophageal cancer patients and the association between SII and the clinicopathological features of esophageal cancer. Eligibility criteria: (I) involved patients diagnosed with EC histopathologically; (II) hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) for pretreatment SII and survival outcomes were reported, or the correlation between SII and clinicopathological characteristics of EC was stated;
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Viksna, Ludmila, Oksana Kolesova, Aleksandrs Kolesovs, Ieva Vanaga, and Seda Arutjunana. Clinical characteristics of COVID-19 patients (Latvia, Spring 2020). Rīga Stradiņš University, 2020. http://dx.doi.org/10.25143/fk2/hnmlhh.

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Data include following variables: Demographics, epidemiological history, comorbidities, diagnosis, complications, and symptoms on admission to the hospital. Also, body’s temperature and SpO2. Blood cells: white cells count (WBC), neutrophils (Neu), lymphocytes (Ly), eosinophils (Eo) and monocytes (Mo), percentages of segmented and banded neutrophils, erythrocytes (RBC), platelet count (PLT), hemoglobin (Hb), and hematocrit (HCT); Inflammatory indicators: erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP); Tissue damage indicators: alanine aminotransferase (ALT), lactate dehydrog
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Li, Li, Jianxiu Yu, and Zhongwei Zhou. Platelet count, mean platelet volume and platelet distribution width in NAFLD patients: A PRISMA-compliant systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.2.0069.

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Sowjanya, Dr Kaniti, Dr Bongu Srinivas, and Dr Metta Lakshmana Rao. A STUDY ON FIBROSCAN COMPARED TO AST TO PLATELET RATIO INDEX(APRI) FOR ASSESSMENT OF LIVER FIBROSIS WITH NONALCOHOLIC FATTY LIVER DISEASE(NAFLD). World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/1606016.

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Background : Nonalcoholic fatty liver disease (NAFLD) is increasingly recognized as a cause of chronic liver disease, and often results in the devastating outcomes of decompensated liver cirrhosis and hepatocellular carcinoma and is an important feature of metabolic syndromes and insulin resistance. The assessment of liver brosis is essential for predicting the prognosis and outcome of all forms of chronic liver disease. A liver biopsy is the gold standard for the assessment of liver brosis, but it has its limitations, which include life-threatening complications. Alternative methods of non-
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Lawanprasert, Somsong, Chaiyo Chaichantipyuth, Supatra Srichairat, Nuansri Niwattisaiwong, and Laddawal Phivthong-ngam. Subchronic exposure of Pueraria mirifica in normal - and high cholesterol diet fed rats : influence on hepatic cytochrome P450, lipid profile and toxicity. Chulalongkorn University, 2004. https://doi.org/10.58837/chula.res.2004.28.

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Pueraria mirifica airy shaw and suvatabandhu, know locally as Kwao Keur, is a plant in family Leguminosae. In this study, effects of P.mirifica on hepatic cytochrome P450 (CYP), serum lipid profile and subchronic toxicity were investigated in male Wistar rats. Rats were randomly divided into four treatment groups as following: normal diet-fed group; normal diet-fed supplemented with P.mirifica group; high cholesterol diet-fed group; high cholesterol diet-fed supplemented with P.mirifica group. Each group comprised 10 rats. P.mirifica was administered orally at a dosage of 100 mg/kg/day for 90
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Premature babies have fewer complications if a lower platelet count is accepted. National Institute for Health Research, 2019. http://dx.doi.org/10.3310/signal-000714.

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