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1

Steggerda, J. J. "Platinum-Gold Cluster Compounds." Comments on Inorganic Chemistry 11, no. 2-3 (1990): 113–29. http://dx.doi.org/10.1080/02603599008035821.

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2

Hartmann, Jörg Thomas, and Hans-Peter Lipp. "Toxicity of platinum compounds." Expert Opinion on Pharmacotherapy 4, no. 6 (2003): 889–901. http://dx.doi.org/10.1517/14656566.4.6.889.

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3

Martínez-Salvador, Sonia, Juan Forniés, Antonio Martín, and Babil Menjón. "Highly Trifluoromethylated Platinum Compounds." Chemistry - A European Journal 17, no. 29 (2011): 8085–97. http://dx.doi.org/10.1002/chem.201100626.

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4

Kasyanenko, Nina, Zhang Qiushi, Vladimir Bakulev, Petr Sokolov, and Konstantin Yakovlev. "DNA Conformational Changes Induced by Its Interaction with Binuclear Platinum Complexes in Solution Indicate the Molecular Mechanism of Platinum Binding." Polymers 14, no. 10 (2022): 2044. http://dx.doi.org/10.3390/polym14102044.

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Platinum anticancer drugs inhibit the division of cancer cells through a DNA binding mechanism. The bimetallic platinum compounds have a possibility for blocking DNA replication via the cross-linking of DNA functional groups at different distances. Many compounds with metals of the platinum group have been tested for possible antitumor activity. The main target of their biological action is a DNA molecule. A combined approach to the study of the interaction of DNA with biologically active compounds of this type is proposed. The capabilities of various methods (hydrodynamic, spectral, microscop
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5

Romano, Alberto, Michele Antonio Capozza, Stefano Mastrangelo, et al. "Assessment and Management of Platinum-Related Ototoxicity in Children Treated for Cancer." Cancers 12, no. 5 (2020): 1266. http://dx.doi.org/10.3390/cancers12051266.

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Platinum compounds are a group of chemotherapeutic agents included in many pediatric and adult oncologic treatment protocols. The main platinum compounds are cisplatin, carboplatin, and oxaliplatin. Their use in clinical practice has greatly improved long-term survival of pediatric patients, but they also cause some toxic effects: ototoxicity, myelosuppression, nephrotoxicity, and neurotoxicity. Hearing damage is one of the main toxic effects of platinum compounds, and it derives from the degeneration of hair cells of the ear, which, not having self-renewal capacity, cannot reconstitute themse
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6

Crespo, Margarita. "Fluorine in Cyclometalated Platinum Compounds." Organometallics 31, no. 4 (2011): 1216–34. http://dx.doi.org/10.1021/om200835g.

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7

Mingos, D. Michael P., and Robert W. M. Wardle. "Homonuclear cluster compounds of platinum." Transition Metal Chemistry 10, no. 12 (1985): 441–59. http://dx.doi.org/10.1007/bf00620708.

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8

MELNIK, M., and C. HOLLOWAY. "Stereochemistry of platinum coordination compounds." Coordination Chemistry Reviews 250, no. 17-18 (2006): 2261–70. http://dx.doi.org/10.1016/j.ccr.2006.02.020.

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9

M.J.C. "Platinum Compounds in Cancer Chemotherapy." Platinum Metals Review 29, no. 2 (1985): 72. http://dx.doi.org/10.1595/003214085x2927272.

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10

Aris, Sheena M., and Nicholas P. Farrell. "Towards Antitumor Activetrans-Platinum Compounds." European Journal of Inorganic Chemistry 2009, no. 10 (2009): 1293–302. http://dx.doi.org/10.1002/ejic.200801118.

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11

Multhaupt, T. P., and S. K. Aggarwal. "Novel Second Generation Platinum Containing Antineoplastic Agents Ssp, Sap, and Poly-Plat and Their Effect on Glucose 6 Phosphate Dehydrogenase (Ec 1.1.1.49) in the Liver and Kidney of Male Wistar Rats." Microscopy and Microanalysis 3, S2 (1997): 57–58. http://dx.doi.org/10.1017/s1431927600007170.

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Poly-(trans-l,2-diaminocyclohexane) platinumj-carboxyamylose (Poly-Plat); 5-SuIfosalicylato-trans-(l,2-diaminocyclohexane) platinum (SSP); and 4-Hydroxy-a-sulfonylphenylacetato (trans 1,2-diaminocyclohexane) platinum (II) (SAP) (Andrulis Pharmaceuticals, Bethesda, MD) are three novel second generation platinum containing antineoplastic compounds. Initial studies indicate that these agents are more effective in the treatment of cancer while at the same time less toxic to the organism as a whole than cisplatin (CDDP). The present study was undertaken to examine the effects of these new compounds
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12

Sharutin, V., and E. Mekhanoshina. "Platinum nitrile compounds. Synthesis, structure, possibilities of practical application." Bulletin of the South Ural State University series "Chemistry" 15, no. 2 (2023): 5–34. http://dx.doi.org/10.14529/chem230201.

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Methods of preparation, some reactions, structural features of platinum nitrile compounds and examples of their possible application are systematized and described based on analysis of the literature published mainly from 2020 to 2023. At the same time, attention is paid to the most effective approaches to obtaining platinum nitrile compounds. The formation reactions of platinum nitrile compounds are considered and information about their biological and catalytic activity is given.
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13

Dey, Sandip, and Vimal K. Jain. "Platinum Group Metal Chalcogenides." Platinum Metals Review 48, no. 1 (2004): 16–29. http://dx.doi.org/10.1595/003214004x4811629.

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Some salientfeatures of platinum group metal compounds with sulfur, selenium or tellurium, known as chalcogenides, primarily focusing on binary compounds, are described here. Their structural patterns are rationalised in terms of common structural systems. Some applications of these compounds in catalysis and materials science are described, and emerging trends in designing molecular precursors for the syntheses of these materials are highlighted.
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14

Ali, Mayyadah Mahmood, and Tavga Ahmed Aziz. "Toxic Effect of Platinum Compounds: Molecular Mechanisms of Toxicity." Al-Rafidain Journal of Medical Sciences ( ISSN: 2789-3219 ) 1 (October 30, 2021): 81–88. http://dx.doi.org/10.54133/ajms.v1i.32.

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Despite their effectiveness as a crucial component of combination chemotherapy regimens against solid tumors, platinum compounds have many serious side effects that limit their use. This review article focuses on the various toxic effects of platinum compounds in cancer patients and the mechanisms of toxicity associated with each of these toxic effects. It also describes the future directions for developing novel platinum compounds, using both animal and human studies. The reference lists of relevant publications were included after searching the Google and Google Scholar databases, PubMed, an
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15

Igarashi, Kentaro, Norio Yamamoto, Toshiharu Shirai, et al. "Efficacy of newly developed platinum complexes against osteosarcoma, bone-targeting platinum, and proteasome inhibitory platinum." Journal of Clinical Oncology 30, no. 15_suppl (2012): 10075. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.10075.

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10075 Background: Cisplatin is one of the most effective anti-cancer drugs available for the treatment of human solid tumors including osteosarcoma. As we had already reported, we have utilized caffeine in our chemotherapy protocol. And we achieved excellent clinical results. But effectiveness of cisplatin has been limited by side effects, and resistance. Here we developed two novel platinum compounds. 3Pt is trinuclear platinum complex bearing geminal bisphosphonate moieties, 1Pt is mononuclear platinum complex which has proteasome inhibitory activity. We performed comparative studies of our
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16

Soejima, Takashi, and Kei-ji Iwatsuki. "Innovative Use of Palladium Compounds To Selectively Detect Live Enterobacteriaceae in Milk by PCR." Applied and Environmental Microbiology 82, no. 23 (2016): 6930–41. http://dx.doi.org/10.1128/aem.01613-16.

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ABSTRACTEthidium monoazide and propidium monoazide (EMA and PMA) have been used in combination with PCR for more than a decade to facilitate the discrimination of live and dead bacteria (LD discrimination). These methods, however, require many laborious procedures, including the use of a darkroom. Here, we demonstrate an innovative use of palladium compounds involving lower limits of detection and quantification of targeted live cells, fewer laborious procedures, lower costs, and potentially higher-throughput analysis than the use of EMA and PMA. We have also recently reported platinum compoun
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17

Galanski, M., and B. K. Keppler. "Synthesis and Characterization of New Ethylenediamine Platinum(IV) Complexes Containing Lipophilic Carboxylate Ligands." Metal-Based Drugs 2, no. 1 (1995): 57–63. http://dx.doi.org/10.1155/mbd.1995.57.

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A series of new ethylenediamine (en) platinum(IV) complexes of the type Pt(IV)enX2A2 , with X2 = cyclobutane-1,1-dicarboxylato (CBDCA), dichloro or bis(decanoato) and A = acetato, dodecanoato, tetradecanoato, hexadecanoato, octadecanoato, adamantanecarboxylato (Ad) or 3α, 12α -diformoxy-5β-cholato (DFCA) were synthesized and characterized by elemental analysis, infrared and NMR (H1 and C13) spectroscopic techniques. Previous platinum(IV) compounds were usually restricted to trans-dihydroxo or trans-dichloro platinum(IV) complexes. Recently trans-dicarboxylato platinum(IV) complexes with mainly
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18

Chung, Tae Shin, Young Mee Na, Shin Won Kang, Ok-Sang Jung, and Young-A. Lee. "Facile generation of platinum(IV) compounds with mixed labile moieties. Hydrogen peroxide oxidation of platinum(II) to platinum(IV) compounds." Transition Metal Chemistry 30, no. 5 (2005): 541–45. http://dx.doi.org/10.1007/s11243-005-2653-2.

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19

Fetoni, A. R., A. Ruggiero, D. Lucidi, et al. "Audiological Monitoring in Children Treated with Platinum Chemotherapy." Audiology and Neurotology 21, no. 4 (2016): 203–11. http://dx.doi.org/10.1159/000442435.

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Platinum compounds constitute the standard treatment for solid tumors in pediatric oncology. The purpose of this study is to assess the impact of platinum compounds in the development of ototoxicity in children following chemotherapy. This study included 160 patients treated with cisplatin and carboplatin for malignant solid diseases from 2007 to 2014. Their audiograms were classified according to the Boston SIOP ototoxicity scale. Twenty-five percent of the children treated with platinum compounds developed ototoxicity. The incidence of ototoxicity was correlated with the type of platinum der
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20

Bulgakov, Roman A., Nina A. Kuznetsova, Olga V. Dolotova, et al. "Synthesis and photophysical properties of covalent conjugates of aqua platinum(II) and octacarboxy-substituted zinc phthalocyanine." Journal of Porphyrins and Phthalocyanines 16, no. 11 (2012): 1217–24. http://dx.doi.org/10.1142/s1088424612501209.

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New covalent conjugates of aqua platinum(II) and octacarboxy-substituted zinc phthalocyanine, bearing one, two, three and four aqua platinum moieties on the periphery of the Pc ligand have been synthesized and characterized. The effect of the stepwise introduction of the aqua platinums on the photophysical and photochemical properties of these compounds has been investigated in dimethylsulfoxide solution. It has been found that aqua platinum moieties have only a limited effect on the dynamics of the singlet and triplet excited states, on the ability to sensitize singlet oxygen formation and on
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21

Ferrari, Giulia, Ines Lopez-Martinez, Thomas Wanek, Claudia Kuntner, and Diego Montagner. "Recent Advances on Pt-Based Compounds for Theranostic Applications." Molecules 29, no. 15 (2024): 3453. http://dx.doi.org/10.3390/molecules29153453.

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Since the discovery of cisplatin’s antitumoral activity and its approval as an anticancer drug, significant efforts have been made to enhance its physiological stability and anticancer efficacy and to reduce its side effects. With the rapid development of targeted and personalized therapies, and the promising theranostic approach, platinum drugs have found new opportunities in more sophisticated systems. Theranostic agents combine diagnostic and therapeutic moieties in one scaffold, enabling simultaneous disease monitoring, therapy delivery, response tracking, and treatment efficacy evaluation
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22

Sharutin, V., and A. Zykova. "Organic platinum compounds containing one platinum–carbon bond. Synthesis, structure, possibilities of practical application." Bulletin of the South Ural State University series "Chemistry" 15, no. 3 (2023): 5–44. http://dx.doi.org/10.14529/chem230301.

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The synthesis methods and structural features of organic platinum compounds containing one platinum–carbon bond have been systematized and described on the basis of analysis of the literature sources published mainly from 2020 to 2023. The discussion of the synthesis methods focuses on the most efficient approaches. Chemical properties of these platinum compounds, schemes of preparation and some mechanisms of reactions are presented. Information on biological activity, catalytic and photoluminescent properties is given.
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23

Szefler, Beata, and Przemysław Czeleń. "Docking of Platinum Compounds on Cube Rhombellane Functionalized Homeomorphs." Symmetry 12, no. 5 (2020): 749. http://dx.doi.org/10.3390/sym12050749.

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Platinum compounds are anti-cancer drugs and can bind to canonical purine bases, mainly guanine, found within double helical DNA. Platinum compounds can be transferred directly to pathologically altered sites in a specific and site-oriented manner by nanocarriers as potential nanocarriers for carboplatin. Two types of nanostructures were used as potential nanocarriers for carboplatin, the first were functionalized C60 fullerene molecules and the second were rhombellanes. The analyzed nanostructures show considerable symmetry, which affects the affinity of the studied nanocarriers and ligands.
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24

Frolov, V. M. "Platinum Metals Complex Catalysts for Liquid-Phase Hydrogenations." Platinum Metals Review 40, no. 1 (1996): 8–18. http://dx.doi.org/10.1595/003214096x401818.

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Results of the syntheses and applications of platinum metals complex catalysts, which are uniquely active for the liquid-phase hydrogenation of unsaturated organic compounds, such as olefins, dienes, acetylenes and aromatics, are described. The platinum metals complex catalysts are synthesised by the interaction between platinum metals compounds and aliphatic amines with sufficiently long alkyl groups (C8 and higher). Similarities are shown in the production of palladium-, platinum-, and rhodium-based catalysts, which involves the formation of hydride ligands, using the hydrogen atoms of the a
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25

De Castro, Federica, Erik De Luca, Michele Benedetti, and Francesco Paolo Fanizzi. "Platinum compounds as potential antiviral agents." Coordination Chemistry Reviews 451 (January 2022): 214276. http://dx.doi.org/10.1016/j.ccr.2021.214276.

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26

Ruggiero, Antonio, Giovanna Trombatore, Silvia Triarico, et al. "Platinum compounds in children with cancer." Anti-Cancer Drugs 24, no. 10 (2013): 1007–19. http://dx.doi.org/10.1097/cad.0b013e3283650bda.

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27

Chakraborty, Bimal K., Nupur Biswas, Kanakendu Choudhury, Rajat K. Neogy, and Das Sarma. "Antitumour Activity of Some Platinum Compounds." Chemotherapy 31, no. 1 (1985): 55–59. http://dx.doi.org/10.1159/000238314.

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28

Muggia, Franco, and Nicholas Farrell. "Platinum coordination compounds in cancer chemotherapy." Critical Reviews in Oncology/Hematology 53, no. 1 (2005): 1–2. http://dx.doi.org/10.1016/j.critrevonc.2004.11.007.

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29

Howell, B. A., R. Rashidianfar, J. R. Glass, B. J. Hutchinson, and D. A. Johnson. "Substitutedcatecholato(1,2-diaminocyclohexane)-platinum(II) compounds." Inorganica Chimica Acta 142, no. 2 (1988): 181–83. http://dx.doi.org/10.1016/s0020-1693(00)81554-6.

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30

van der Vijgh, W. J. F., and I. Klein. "Protein binding of five platinum compounds." Cancer Chemotherapy and Pharmacology 18, no. 2 (1986): 129–32. http://dx.doi.org/10.1007/bf00262281.

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31

Goodisman, Jerry, Douglas Hagrman, Kirk A. Tacka, and Abdul-Kader Souid. "Analysis of cytotoxicities of platinum compounds." Cancer Chemotherapy and Pharmacology 57, no. 2 (2005): 257–67. http://dx.doi.org/10.1007/s00280-005-0041-4.

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32

Reedijk, J., E. L. M. Lempers, A. F. Struik, and N. Boogaard. "Intracellular reactions of platinum antitumor compounds." Journal of Inorganic Biochemistry 36, no. 3-4 (1989): 282. http://dx.doi.org/10.1016/0162-0134(89)84397-1.

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33

Gibson, D., H. Sheshinski, H. M. Greenblatt, A. Bino, and G. Shoham. "Adducts of platinum compounds with proteins." Journal of Inorganic Biochemistry 43, no. 2-3 (1991): 605. http://dx.doi.org/10.1016/0162-0134(91)84576-u.

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34

Bednarski, Patrick J., Ronald Gust, Thilo Spruss, et al. "Platinum compounds with estrogen receptor affinity." Cancer Treatment Reviews 17, no. 2-3 (1990): 221–31. http://dx.doi.org/10.1016/0305-7372(90)90052-h.

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35

Bremi, Juliane, Margherita Fontana, Walter Caseri, and Paul Smith. "Polymeric Quasi-one-dimensional Platinum Compounds." Macromolecular Symposia 235, no. 1 (2006): 80–88. http://dx.doi.org/10.1002/masy.200650311.

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36

Turkson, James, Shumin Zhang, Jay Palmer, et al. "Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity." Molecular Cancer Therapeutics 3, no. 12 (2004): 1533–42. http://dx.doi.org/10.1158/1535-7163.1533.3.12.

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Abstract DNA-alkylating agents that are platinum complexes induce apoptotic responses and have wide application in cancer therapy. The potential for platinum compounds to modulate signal transduction events that contribute to their therapeutic outcome has not been extensively examined. Among the signal transducer and activator of transcription (STAT) proteins, Stat3 activity is frequently up-regulated in many human tumors. Various lines of evidence have established a causal role for aberrant Stat3 activity in malignant transformation and provided validation for its targeting in the development
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37

Coffetti, Giulia, Martina Moraschi, Giorgio Facchetti, and Isabella Rimoldi. "The Challenging Treatment of Cisplatin-Resistant Tumors: State of the Art and Future Perspectives." Molecules 28, no. 8 (2023): 3407. http://dx.doi.org/10.3390/molecules28083407.

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One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In particular, the research studies reported herein focus on the capability of some platinum-based anticancer agents to bypass resistance to chemotherapy, which is typical of well-known drugs such as cisplatin. Regarding platinum (II) complexes, this review deals with complexes in
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38

Xiao, Xiao, James Trevor Oswald, Ting Wang, Weina Zhang, and Wenliang Li. "Use of Anticancer Platinum Compounds in Combination Therapies and Challenges in Drug Delivery." Current Medicinal Chemistry 27, no. 18 (2020): 3055–78. http://dx.doi.org/10.2174/0929867325666181105115849.

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As one of the leading and most important metal-based drugs, platinum-based pharmaceuticals are widely used in the treatment of solid malignancies. Despite significant side effects and acquired drug resistance have limited their clinical applications, platinum has shown strong inhibitory effects for a wide assortment of tumors. Drug delivery systems using emerging technologies such as liposomes, dendrimers, polymers, nanotubes and other nanocompositions, all show promise for the safe delivery of platinum-based compounds. Due to the specificity of nano-formulations; unwanted side-effects and dru
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39

Yumuk, P. F., M. Teomete, F. Dane, D. Cabuk, G. Basaran, and N. S. Turhal. "Impact of dose reductions of platinum compounds on survival in stage IIIB/IV non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 27, no. 15_suppl (2009): e19055-e19055. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e19055.

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e19055 Background: Platinum compounds are the main component of the CT in NSCLC. Standard recommended doses of cisplatin/carboplatin is usually couldn’t be administered and dose reductions are necessary because of side effects. We aimed to determine the effect of dose reductions of platinums on outcome of stage IIIB/IV NSCLC. Methods: Data of 420 patients were retrospectively reviewed. A platinum analogue was used in combination with vinorelbine, gemcitabine, paclitaxel, docetaxel or etoposide as first line treatment in 85% patients. Cumulative platinum doses and dose reduction ratios compared
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40

Ivanova, Stefka, Stefan Balkanski, Petar Atanasov, et al. "Antitumor and antioxidant activity of some metal complex compounds." Pharmacia 70, no. 2 (2023): 375–82. http://dx.doi.org/10.3897/pharmacia.70.e105845.

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In the last few years, interest in platinum drugs has increased. Successful treatment depends to a large extent on complex therapy and early diagnosis, which determines the great importance of knowledge of risk groups, clinical symptoms, and targeted use of diagnostic methods with biomarkers, biopsy and diagnostic imaging for early detection of the malignant process. Today, the mono-target strategy is being replaced by a poly-target therapy strategy, which achieves greater clinical efficacy in tumors with defined biomarkers. Key developments include elucidation of the mechanisms of tumor resis
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41

Ivanova, Stefka, Stefan Balkanski, Petar Atanasov, et al. "Antitumor and antioxidant activity of some metal complex compounds." Pharmacia 70, no. (2) (2023): 375–82. https://doi.org/10.3897/pharmacia.70.e105845.

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In the last few years, interest in platinum drugs has increased. Successful treatment depends to a large extent on complex therapy and early diagnosis, which determines the great importance of knowledge of risk groups, clinical symptoms, and targeted use of diagnostic methods with biomarkers, biopsy and diagnostic imaging for early detection of the malignant process. Today, the mono-target strategy is being replaced by a poly-target therapy strategy, which achieves greater clinical efficacy in tumors with defined biomarkers. Key developments include elucidation of the mechanisms of tumor resis
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42

Chotkowski, Maciej, Franciszek Miklaszewicz, and Andrzej Czerwinski. "The Platinum Catalyst Prepared from Platinum Carbonyls." Journal of New Materials for Electrochemical Systems 16, no. 4 (2013): 263–67. http://dx.doi.org/10.14447/jnmes.v16i4.151.

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Pt catalysts for methanol electro-oxidation were prepared by thermal decomposition of platinum carbonyls. [Pt3(CO)6]n2- were synthesized from inorganic platinum compounds (PtCl4 or (NH4)2PtCl4) in H2O-MeOH solutions using carbon monoxide as a reducing agent. The progress of the platinum carbonyls synthesis reaction and its performance were monitored using UV-Vis spectroscopy. The obtained results clearly indicate the possibility of using platinum carbonyls as intermediates for the synthesis of pure and finely divided platinum particles. The electrochemical tests of the platinum powders perform
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43

Muenchen, H. J., S. K. Aggarwal, H. K. Misra, and P. J. Andrulis. "Morphological and Histochemical Changes in Macrophage Activity After Novel Anti-Neoplastic Platinum Agents." Microscopy and Microanalysis 3, S2 (1997): 11–12. http://dx.doi.org/10.1017/s1431927600006942.

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Poly-[(trans-1,2-diaminocyclohexane) platinumj-carboxyamylose (“poly-plat”), 5-sulfosalicylato-trans -(1,2-diaminocyclohexane) platinum (SSP), and 4-hydroxy-∝-sulfonylphenylacetato (trans 1,2-diaminocyclohexane) platinum (II) (SAP) are second generation analogs of cisplatin (CDDP) with higher efficacy and potency than cisplatin. This is particularly true of “poly-plat” which contains 1/5 the platinum of CDDP. In order to understand the mechanism of action of these compounds, isolated murine peritoneal macrophages in culture medium were treated with “poly-plat”, SSP, or SAP (5 μg/ml) for 2 h. D
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44

Sharutin, V., and A. Rybakova. "Organic platinum compounds containing two or more platinum–carbon bonds. Synthesis, structure, possibilities of practical application." Bulletin of the South Ural State University series "Chemistry" 15, no. 3 (2023): 45–88. http://dx.doi.org/10.14529/chem230302.

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Methods of obtaining together with some reactions, and structural features of organic platinum compounds containing two or more platinum-carbon bonds, as well as examples of their possible use, have been systematized and described based on the analysis of the literature published mainly from 2020 to 2023, In discussion of the synthesis methods, the attention is mainly paid to the most efficient approach to obtain them. Formation reactions of organic platinum compounds are considered and information about their biological and catalytic activity is given.
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45

R.N., PANDEY, KUMAR ARUN, S. P. SINGH R., N. SAHAY A., and KANT KUMAR SHASHI. "Some Low-valent Organometallic Complexes of Palladium(o), Platinum(o) and Rhodium(I)." Journal of Indian Chemical Society Vol. 69, Dec 1992 (1992): 804–6. https://doi.org/10.5281/zenodo.6017809.

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P. G. Centre of Chemistry (M. U.), College of Commerce, Patna-800 020 <em>Manuscript received 19 January 1992, revised 6 July 1992, accepted 25 August 1992</em> Some low-valent organometallic complexes of Pd<sup>0</sup>, Pt<sup>0</sup>&nbsp;and Rh<sup>I</sup>&nbsp;have been prepared and their tentative structure are assigned using various physicochemical data All Pd<sup>O</sup>&nbsp;and Pt<sup>O</sup>&nbsp;compounds are tetrahedral but compounds of Int have square planar configuration. Oxidation state of metals in these compounds are determined iodometrically. The ligand 3-(4 pyridyl) 4-phenyl
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46

Bissinger, Herbert, та Wolfgang Beck. "Metallkomplexe mit biologisch wichtigen Liganden, XXXIX [1]. Platin(IV)-Komplexe mit α-Aminosäure-und Peptidestern; 15N-und 195Pt-NMR-Spektren von α-Aminosäuren-Platin-Komplexen / Metal Complexes with Biologically Important Ligands, XXXIX [1]. Platinum(IV) Complexes with α-Amino Acid Esters and Peptide Esters; 13N and 195Pt NMR Spectra of Platinum Complexes with α-Amino Acids". Zeitschrift für Naturforschung B 40, № 4 (1985): 507–11. http://dx.doi.org/10.1515/znb-1985-0412.

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The platinum(IV) complexes PtX4L2 (X = Cl, Br; 2 X = oxalate; L = glyOEt, glyglyOEt, gly-cleuOEt; 2 L = metOEt) have been obtained by oxidative addition of halogenes to platinum(II) compounds PtX2L2. A high field shift of δ15N ( ∼ 50 ppm) is observed for the coordinated amino acid ligand of various platinum complexes, compared to the free ligand. Platinum(II) and platinum(IV) can be distinguished by their 195Pt NMR signals.
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47

Melník, Milan, Peter Mikuš, and Clive Eduard Holloway. "Platinum organometallic compounds: classification and analysis of crystallographic and structural data of monomeric five and higher coordinated." Reviews in Inorganic Chemistry 33, no. 1 (2013): 13–103. http://dx.doi.org/10.1515/revic-2013-0001.

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AbstractFour hundred and twenty monomeric organoplatinum compounds, in which platinum atoms are five- and higher coordinated, are analyzed. The platinum atoms are found in the oxidation states +2, +3 and +4. The Pt(II) compounds by far prevail. There are wide varieties of the inner coordination spheres about the platinum centers. The Pt(II) compounds are five-coordinated (trigonal bipyramidal and square pyramidal), six-coordinated (different degrees of distortion), seven-coordinated (pentagonal bipyramidal, piano stool) and sandwiched (PtC10). The Pt(III) compound is square-planar. The Pt(IV)
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48

Galanski, M., B. K. Keppler, and Th Klenner. "Antitumor platinum compounds linked to amino phosphonic acids: Drug targeting with osteotropic platinum compounds against bone malignancies." Journal of Inorganic Biochemistry 59, no. 2-3 (1995): 212. http://dx.doi.org/10.1016/0162-0134(95)97318-k.

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49

Melník, Milan, Peter Mikuš, and Clive Holloway. "Crystalographic and structural characterization of heterometallic platinum compounds. Part III: heterotrinuclear compounds." Open Chemistry 11, no. 6 (2013): 827–900. http://dx.doi.org/10.2478/s11532-013-0226-3.

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AbstractThis review article includes over three hundred and sixty heterotrinuclear platinum complexes of the composition Pt2M (205 examples), PtM2 (132 examples) and PtMM (24 examples). The heterometals include the non-transition and transition metals. Three metal atoms form a wide variability of frameworks: M3 triangular, dicapped M3 triangular, V shaped M3, M3 linear, five-, six- and seven- metallocycles and unique structures of which triangular and linear are the most common. This has led to a rich chemistry of platinum not only from variability of metals, but also from their framework and
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50

Rochon, F. D., and P. C. Kong. "Iodo-bridged complexes of platinum(II) and synthesis of cis mixed-amine platinum(II) compounds." Canadian Journal of Chemistry 64, no. 9 (1986): 1894–96. http://dx.doi.org/10.1139/v86-312.

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Iodo-bridged platinum(II) dimers, [Pt(L)I2]2 with ligands (L) containing nitrogen as the donor atom, have been synthesized from the reactions of cis-[Pt(L)2I2] with perchloric acid. The dimers can be cleaved in aqueous media by a second nitrogen ligand to produce isometrically pure cis-[Pt(L)(L′)I2].These compounds can finally be converted to the chloro or carboxylato compounds by precipitating the iodo ligands with a silver salt and adding KCl or a carboxylate salt. Several compounds of the types cis-[Pt(L)(L′)Cl2] and cis-[Pt(L)(L′)(dicarboxylate)] were thus prepared. A few dimers of the typ
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