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Books on the topic 'Pleiotropy'

Author: Grafiati

Published: 4 June 2021

Last updated: 26 July 2025

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1

Kumar, Ravinder, Muhammad Ahsan Altaf, Milan Kumar Lal, and Rahul Kumar Tiwari, eds. Melatonin in Plants: A Pleiotropic Molecule for Abiotic Stresses and Pathogen Infection. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-6741-4.

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2

Hildebrand, Dominic. The 'inhibitor of NF-kappa B zeta' is a pleiotropic key regulator of macrophage function. s.n.], 2013.

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3

Brown, Kyle Michael. The evolutionary genetics of epistasis an pleiotropy. 2009.

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4

Renton, Alan E., and Alison M. Goate. Genetics of Dementia. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0051.

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The genetic architecture of dementia is polygenic and complex, with risk alleles spanning frequency–effect size space. Despite significant progress, most genes influencing these disorders await discovery. Known risk loci implicate perturbed pathways that coalesce around recurring mechanistic themes, notably the autophagosome-lysosome system, the cytoskeleton, endocytosis, innate immunity, lipid metabolism, mitochondria, and the ubiquitin-proteasome system. Phenotypic and pathophysiological pleiotropy suggests some conditions form continuous clinicopathogenetic disease spectra blurring classica

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5

Gu, Xun. Statistical Analysis of Molecular and Genomic Evolution. Oxford University PressOxford, 2024. http://dx.doi.org/10.1093/oso/9780198816515.001.0001.

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Abstract This book introduces up-to-date methods in statistics and bioinformatics for the study of molecular and genome evolution. It first provides a concise overview of molecular evolutionary analysis and phylogenetic inference. The following chapters cover four research themes: evolution of protein functionality and functional divergence (Chapters 3 and 4); effective gene pleiotropy estimation under the genotype-phenotype mapping model of protein evolution (Chapter 5); evolution of genetic robustness after gene duplication (Chapter 6), and the statistical models of transcriptome evolution (

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6

Khavandi, Kaivan, Halima Amer, Sarah Withers, and Behdad Afzali. Pleiotropic effects of vitamin D. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0127.

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Vitamin D is a fat-soluble steroid pro-hormone integral to physiological health, fulfilling a central role in skeletal mineralization, bone metabolism, and immune biology. Although vitamin D is synthesized photochemically in the skin and some is absorbed from dietary sources, vitamin D insufficiency and deficiency are very common. Epidemiological studies have demonstrated a strong association between vitamin D and kidney and heart disease, and some supplementation studies have suggested that repletion may prevent and/or ameliorate cardiorenal injury. This chapter focuses on vitamin D biology a

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7

Baloch, Faheem Shahzad, and Yong Suk Chung. Melatonin: An Ubiquitous Pleiotropic Molecule. Elsevier Science & Technology, 2024.

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8

Pludowski, Pawel, William B. Grant, Jerzy Konstantynowicz, and Michael F. Holick, eds. Classic and Pleiotropic Actions of Vitamin D. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88963-008-0.

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9

Lohmeyer, Michael. Nickeltransport bei Alcaligenes eutrophus und Pleiotropie chromosomaler Transportmutanten. 1985.

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10

Vitamin B and Vitamin E: Pleiotropic and Nutritional Benefits. IntechOpen, 2024.

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11

Pludowski, Pawel, ed. COVID-19 and Other Pleiotropic Actions of Vitamin D. MDPI, 2023. http://dx.doi.org/10.3390/books978-3-0365-6935-2.

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12

Hladkykh, Fedir, Nataliia Stepaniuk, and Heorhyi Stepaniuk. Pharmacodynamics of ibuprofen in the light if pleiotropic effects of Vinboron. ТОВ «Твори», 2022. http://dx.doi.org/10.46879/2022.2.

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This monograph summarizes the experimental studies on the pleiotropic effects of vinboron on pharmacodynamics of ibuprofen which is a widely used non-steroidal anti-inflammatory drug. Data on the effect of ibuprofen and its combination with vinboron on gastric secretion, proliferation and apoptosis of gastric epitheliocytes are presented. The effectiveness of the combined use of ibuprofen and vinboron in the treatment of experimental rheumatoid arthritis was evaluated in hematological, biochemical and pathomorphological studies. The monograph will be of intersest for clinicians, pharmacologist

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13

Crum, Albert B. Glutathione Synthesis: Unraveling the Pleiotropic Paradox and Its Vital Immune Role. Wiley & Sons, Incorporated, John, 2017.

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14

Calcitonin gene-related peptide: The first decade of a novel pleiotropic neuropeptide. New York Academy of Sciences, 1992.

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15

Altaf, Muhammad Ahsan, Milan Kumar Lal, and Rahul Kumar Tiwari. Melatonin in Plants: A Pleiotropic Molecule for Abiotic Stresses and Pathogen Infection. Springer, 2023.

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16

Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases. MDPI, 2019. http://dx.doi.org/10.3390/books978-3-03897-693-6.

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17

Hellweg, Rainer. Nerve Growth Factor Bei Neuropsychiatrischen Erkrankungen: Ein Pleiotroper Modulator Mit Peripherer und Zentralnervöser Wirkung. Steinkopff, Dietrich, 2013.

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18

Rustum, Youcef M. Pleiotropic Action of Selenium in the Prevention and Treatment of Cancer, and Related Diseases. Mdpi AG, 2019.

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19

Hellweg, Rainer. Der Nerve Growth Factor bei neuropsychiatrischen Erkrankungen: Ein pleiotroper Modulator mit peripherer und zentralnervöser Wirkung. Steinkopff, 2012.

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20

Friel, Howard, and Sally A. Frautschy. Paradigm Shift to Prevent and Treat Alzheimer's Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols. Elsevier Science & Technology Books, 2017.

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21

Ladda, Ekkehart. R-Verapamil als Modulator der pleiotropen Zytostatikaresistenz in Kombination mit zytostatischer Chemotherapie: Eine Phase-I-Studie. 1995.

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22

(Editor), Peter Holzer, Yvette Tache (Editor), and Michael G. Rosenfeld (Editor), eds. Calcitonin Gene-Related Peptide: The First Decade of a Novel Pleiotropic Neuropeptide (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1992.

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23

(Editor), Yvette Tache, Peter Holzer (Editor), and M. Geoff Rosenfeld (Editor), eds. Calcitonin Gene-related Peptide: The First Decade of a Novel Pleiotropic Neuropeptide (Annals of the New York Academy of Sciences). New York Academy of Sciences, 1992.

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24

Diederich, Nico J., Martin Brüne, Katrin Amunts, and Christopher G. Goetz, eds. The Evolutionary Roots of Human Brain Diseases. Oxford University PressNew York, 2024. http://dx.doi.org/10.1093/med/9780197676592.001.0001.

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Abstract The Evolutionary Roots of Human Brain Diseases takes an innovative approach and assembles recent findings ranging from evolutionary biology and anthropology to clinical neurosciences, all showing the price on health of human brain evolution. Written by experts in their field, the chapters explore the tenet that extensive human brain development during evolution has given rise to exclusively human brain diseases, both priming and impacting their clinical expression. There are presentations on cerebral cellular specificities or human-specific network developments, detailed discussions o

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25

Gropler, Robert J. Imaging of Myocardial Metabolism. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.003.0025.

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Abnormalities in myocardial substrate metabolism play a key role in the pathogenesis of a host of cardiac disease processes. The importance is highlighted by the routine clinical use of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) to measure myocardial glucose metabolism to detect viable tissue in patients with ischemic cardiomyopathy and the development of novel therapies designed to modulate myocardial metabolism. Our understanding of myocardial metabolism has benefitted from the application of advanced molecular biologic techniques and the development of elegant gen

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