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Journal articles on the topic 'PMAD'

Author: Grafiati

Published: 30 June 2021

Last updated: 29 July 2025

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1

Floyd James, Kortney, Keisha Reaves, Misty C. Richards, and Kristen R. Choi. "Enhancing Obstetric Healthcare Providers’ Knowledge of Black Maternal Mental Health: A Feasibility Study." International Journal of Environmental Research and Public Health 21, no. 10 (2024): 1374. http://dx.doi.org/10.3390/ijerph21101374.

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Despite guidelines for screening and treating perinatal mood and anxiety disorders (PMADs), systemic issues and clinician biases often result in unmet mental health needs in Black women. This study assessed the feasibility and impact of comprehensive PMAD training on obstetric healthcare providers’ attitudes, knowledge, and implicit racial biases. We conducted a feasibility study with two cohorts of healthcare providers who received either in-person or virtual training. The training focused on PMADs, implicit bias, and culturally responsive care. Participants completed pre- and post-training a

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Dorfman, R., and B. Z. Shilo. "Biphasic activation of the BMP pathway patterns the Drosophila embryonic dorsal region." Development 128, no. 6 (2001): 965–72. http://dx.doi.org/10.1242/dev.128.6.965.

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The BMP pathway patterns the dorsal region of the Drosophila embryo. Using an antibody recognizing phosphorylated Mad (pMad), we followed signaling directly. In wild-type embryos, a biphasic activation pattern is observed. At the cellular blastoderm stage high pMad levels are detected only in the dorsal-most cell rows that give rise to amnioserosa. This accumulation of pMad requires the ligand Screw (Scw), the Short gastrulation (Sog) protein, and cleavage of their complex by Tolloid (Tld). When the inhibitory activity of Sog is removed, Mad phosphorylation is expanded. In spite of the uniform

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Puspitasari, Ajeng J., Dagoberto Heredia, Elise Weber, et al. "Perinatal Mood and Anxiety Disorder Management in Multicenter Community Practices: Clinicians’ Training, Current Practices and Perceived Strategies to Improve Future Implementation." Journal of Primary Care & Community Health 12 (January 2021): 215013272199688. http://dx.doi.org/10.1177/2150132721996888.

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Background: This study aimed to explore clinicians’ perspectives on the current practice of perinatal mood and anxiety disorder (PMAD) management and strategies to improve future implementation. Methods: This study had a cross-sectional, descriptive design. A 35-item electronic survey was sent to clinicians (N = 118) who treated perinatal women and practiced at several community clinics at an academic medical center in the United States. Results: Among clinicians who provided care for perinatal women, 34.7% reported never receiving PMAD management training and 66.3% had less than 10 years of e

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Nguyen, Tho Huu, Tae Hee Han, Stuart J. Newfeld, and Mihaela Serpe. "Selective Disruption of Synaptic BMP Signaling by a Smad Mutation Adjacent to the Highly Conserved H2 Helix." Genetics 216, no. 1 (2020): 159–75. http://dx.doi.org/10.1534/genetics.120.303484.

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Bone morphogenetic proteins (BMPs) shape normal development and function via canonical and noncanonical signaling pathways. BMPs initiate canonical signaling by binding to transmembrane receptors that phosphorylate Smad proteins and induce their translocation into the nucleus and regulation of target genes. Phosphorylated Smads also accumulate at cellular junctions, but this noncanonical, local BMP signaling modality remains less defined. We have recently reported that phosphorylated Smad (pMad in Drosophila) accumulates at synaptic junctions in protein complexes with genetically distinct comp

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Shklarski, Liat, and Lauren Kalogridis. "Promotion and Prevention of Perinatal Mood and Anxiety Disorders: Doulas’ Roles and Challenges." Journal of Perinatal Education 31, no. 2 (2022): 82–93. http://dx.doi.org/10.1891/jpe-2021-00058.

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Doulas are uniquely positioned to support women during birth and the postpartum period and can serve as a great asset to identify symptoms of perinatal mood and anxiety disorders (PMADs) and refer women to treatment. The goal of this study is to increase knowledge of doulas’ training on PMADs and their work with women who experienced symptoms. Results from a survey of 156 doulas and interviews with 27 doulas indicate that they felt ill-prepared to identify PMAD symptoms. They struggled in referring patients to the appropriate services and finding professional support related to supporting clie

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Miranda, Veronica. "Perinatal Mood and Anxiety Disorder in Times of COVID." Commoning Ethnography 5, no. 1 (2023): 45–66. http://dx.doi.org/10.26686/ce.v5i1.8057.

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Between 15-20% of pregnant and birthing people in the United States experience symptoms of Perinatal Mood and Anxiety Disorders (PMAD). This percentage is higher for individuals who are low income, racially minoritized, and/or marginalized. Social systems of care and support have been shown to reduce symptoms of PMAD and help optimize the health of pregnant and postpartum people. For many people, COVID-19 further exacerbated the negative impacts of PMAD, largely because of disruptions of social support networks and health care resources. This article uses testimonio and autoethnography to disc

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Sardi, Justin, Muhammed Burak Bener, Taylor Simao, Abigail E. Descoteaux, Boris M. Slepchenko, and Mayu Inaba. "Mad dephosphorylation at the nuclear pore is essential for asymmetric stem cell division." Proceedings of the National Academy of Sciences 118, no. 13 (2021): e2006786118. http://dx.doi.org/10.1073/pnas.2006786118.

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Stem cells divide asymmetrically to generate a stem cell and a differentiating daughter cell. Yet, it remains poorly understood how a stem cell and a differentiating daughter cell can receive distinct levels of niche signal and thus acquire different cell fates (self-renewal versus differentiation), despite being adjacent to each other and thus seemingly exposed to similar levels of niche signaling. In theDrosophilaovary, germline stem cells (GSCs) are maintained by short range bone morphogenetic protein (BMP) signaling; the BMP ligands activate a receptor that phosphorylates the downstream mo

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Zhou, Nan, Qianhao Zhao, Rui Li, et al. "Does Anatomic Phenotype of Mitral Annular Disjunction Impact Survival? An Autopsy-Based Retrospective Study." Journal of Cardiovascular Development and Disease 8, no. 12 (2021): 174. http://dx.doi.org/10.3390/jcdd8120174.

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Controversies have been raised regarding the prevalence and potential clinical significance of mitral annular disjunction (MAD). We aim to address the anatomic characteristics of MAD and their association, if any, on survival. We retrospectively reviewed 1373 consecutive dissected hearts (1017 men, mean age at death 44.9 ± 0.4 y) and frequently detected MAD (median disjunctional length: 2.0 mm, range: 1.5 mm~8.5 mm), with the prevalence of 92.1% over the entire mitral annulus and 74.9% within the posterior annulus (pMAD). The presence of pMAD was associated with increased all-cause mortality (

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Dolezal, Darin, Zhiyan Liu, Qingxiang Zhou, and Francesca Pignoni. "Fly LMBR1/LIMR-type protein Lilipod promotes germ-line stem cell self-renewal by enhancing BMP signaling." Proceedings of the National Academy of Sciences 112, no. 45 (2015): 13928–33. http://dx.doi.org/10.1073/pnas.1509856112.

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Limb development membrane protein-1 (LMBR1)/lipocalin-interacting membrane receptor (LIMR)-type proteins are putative nine-transmembrane receptors that are evolutionarily conserved across metazoans. However, their biological function is unknown. Here, we show that the fly family member Lilipod (Lili) is required for germ-line stem cell (GSC) self-renewal in the Drosophila ovary where it enhances bone morphogenetic protein (BMP) signaling. lili mutant GSCs are lost through differentiation, and display reduced levels of the Dpp transducer pMad and precocious activation of the master differentiat

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Feng, Ganlin, Yaoliang Chen, Lamin R. Mansaray, Hongfeng Xu, Aoni Shi, and Yanling Chen. "Propagation of Meteorological Drought to Agricultural and Hydrological Droughts in the Tropical Lancang–Mekong River Basin." Remote Sensing 15, no. 24 (2023): 5678. http://dx.doi.org/10.3390/rs15245678.

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In the past several decades, drought events have occurred frequently around the world. However, research on the propagation of drought events has not been adequately explored. This study investigated the drought propagation process from meteorological drought to agricultural drought (PMAD) and from meteorological drought to hydrological drought (PMHD) using a 72-year reanalysis dataset in the tropical Lancang–Mekong River Basin. Firstly, we used a new method—Standardized Drought Analysis Toolbox—to construct drought indices. Then, a linear method (Pearson correlation analysis) and a nonlinear

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Yao, Xincheng, Chongyang Zhang, Ruoqi Li, Jun Sun, and Zhenyu Liu. "One-for-All: Proposal Masked Cross-Class Anomaly Detection." Proceedings of the AAAI Conference on Artificial Intelligence 37, no. 4 (2023): 4792–800. http://dx.doi.org/10.1609/aaai.v37i4.25604.

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One of the most challenges for anomaly detection (AD) is how to learn one unified and generalizable model to adapt to multi-class especially cross-class settings: the model is trained with normal samples from seen classes with the objective to detect anomalies from both seen and unseen classes. In this work, we propose a novel Proposal Masked Anomaly Detection (PMAD) approach for such challenging multi- and cross-class anomaly detection. The proposed PMAD can be adapted to seen and unseen classes by two key designs: MAE-based patch-level reconstruction and prototype-guided proposal masking. Fi

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Cruz, Bruno de Oliveira, Thiago Mendes Rosa, and Luiz Rubens Câmara de Araújo. "Área metropolitana de Brasília e quantificação de fluxos a partir de pesquisas domiciliares." Boletim Regional, Urbano e Ambiental (BRUA): n. 22 22 (December 22, 2020): 83–99. http://dx.doi.org/10.38116/brua22art7.

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Este artigo apresenta um histórico da a Pesquisa Metropolitana por Amostra de Domicílios (PMAD), incluindo alguns detalhes sobre avanços na metodologia de coleta e melhoria nos cadastros de endereços. Em seguida são analisados os diversos fluxos, começando pelo deslocamento casa-trabalho, incluindo o impacto sobre salários do local de trabalho. Os demais fluxos são descritos nas subseções sobre saúde, educação e consumo. O que se evidencia dos dados da PMAD é uma dinâmica metropolitana clara entre o Distrito Federal e os demais municípios da Periferia Metropolitana de Brasília (PMB), ainda que

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Hunt, Joanna. "Implementing a PMAD Screening Program for Antepartum Inpatients." Journal of Obstetric, Gynecologic & Neonatal Nursing 52, no. 4 (2023): S44. http://dx.doi.org/10.1016/j.jogn.2023.05.063.

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Wu, Qi, Shaohua Gou, Jinglun Huang, Guijuan Fan, Shiwei Li, and Mengyu Liu. "Hyper-branched structure—an active carrier for copolymer with surface activity, anti-polyelectrolyte effect and hydrophobic association in enhanced oil recovery." RSC Advances 9, no. 29 (2019): 16406–17. http://dx.doi.org/10.1039/c9ra01554j.

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Herein, a hyper-branched polymer h-PMAD with, simultaneously, surface activity, an anti-polyelectrolyte effect and a hydrophobic association was prepared via aqueous solution free radical polymerization, and characterized by IR, NMR, TG–DTG and SEM.

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Hutchens, Bridget F., and Frances E. Likis. "A mental health acronym that must be stopped: PMAD." Archives of Women's Mental Health 22, no. 5 (2018): 709. http://dx.doi.org/10.1007/s00737-018-0932-0.

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Herbst, Kelsey, Natasha P. Malmin, Sudeshna Paul, et al. "Examining recurrent hurricane exposure and psychiatric morbidity in Medicaid-insured pregnant populations." PLOS Mental Health 1, no. 1 (2024): e0000040. http://dx.doi.org/10.1371/journal.pmen.0000040.

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The wide-ranging mental health consequences of a major hurricane have been widely documented, but important gaps remain in understanding the mental health burden of recurrent exposure to multiple hurricanes. The objective of this study was to examine the mental health burden in at-risk pregnant populations recurrently exposed to major hurricanes Matthew (2016), Florence (2018), Michael (2018), and Dorian (2019). Daily emergency department (ED) admissions were obtained on pregnant Medicaid beneficiaries for incident maternal disorders of pregnancy (MDP), perinatal mood and anxiety disorders (PM

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Erdonmez, D., S. Mosayyebi, K. Erkan, et al. "Nanofabrication and characterization of PVA–organofiller/Ag nanocoatings on pMAD plasmids." Applied Surface Science 318 (November 2014): 127–31. http://dx.doi.org/10.1016/j.apsusc.2014.02.007.

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Arnaud, Maryvonne, Arnaud Chastanet, and Michel DÃ¯Â¿Â½barbouillÃ¯Â¿Â½. "New Vector for Efficient Allelic Replacement in Naturally Nontransformable, Low-GC-Content, Gram-Positive Bacteria." Applied and Environmental Microbiology 70, no. 11 (2004): 6887–91. http://dx.doi.org/10.1128/aem.70.11.6887-6891.2004.

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ABSTRACT A shuttle vector designated pMAD was constructed for quickly generating gene inactivation mutants in naturally nontransformable gram-positive bacteria. This vector allows, on X-Gal (5-bromo-4-chloro-3-indolyl-β-d-galactopyranoside) plates, a quick colorimetric blue-white discrimination of bacteria which have lost the plasmid, greatly facilitating clone identification during mutagenesis. The plasmid was used in Staphylococcus aureus, Listeria monocytogenes, and Bacillus cereus to efficiently construct mutants with or without an associated antibiotic resistance gene.

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Bowen, A. "World maternal mental health day." European Psychiatry 41, S1 (2017): s900. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1838.

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IntroductionAs many as 20% of mothers experiences some type of perinatal mood and anxiety disorder (PMAD) worldwide. Women of every culture, age, income level, and race are at risk for PMADs with potential effects to mother and child.ObjectivesTo promote awareness of maternal mental health and PMADs.MethodAn international task force met via online videoconference to make plans for the inaugural World Maternal Mental Health Day. The task force soon grew to include representatives from around the globe with a common goal to increase awareness of and influence policy about maternal mental health.

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Bloyd, Cooper, Snehal Murthy, Clara Song, Linda S. Franck, and Christina Mangurian. "National Cross-Sectional Study of Mental Health Screening Practices for Primary Caregivers of NICU Infants." Children 9, no. 6 (2022): 793. http://dx.doi.org/10.3390/children9060793.

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Universal screening for postpartum mood and anxiety disorders (PMADs) has been recommended for all new parents at outpatient postpartum and well-child visits. However, parents of newborns admitted to the NICU are rarely able to access these services during their infant’s prolonged hospitalization. The objective of this study was to determine the prevalence of mental health screening and treatment programs for parents or other primary caregivers in NICUs across the country. In this cross-sectional study, US NICU medical directors were invited to complete an online survey about current practices

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Babu, J. Jai Jaganath, M. Rohith, L. S. Monish Krishnan, and T. Chanakkiyan. "Hybrid Despeckling for Ultrasound Images Using Sticks Filter and Fourth-Order PDE for Enhanced Diagnostic Precision." Journal of Computers, Mechanical and Management 3, no. 5 (2024): 1–8. https://doi.org/10.57159/jcmm.3.5.24167.

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Speckle noise in ultrasound imaging poses significant challenges by degrading image quality and affecting diagnostic precision. This study evaluates and compares the performance of established despeckling algorithms, including Lee, Kuan, Frost, Non-Local Means, and PMAD filters, as well as advanced techniques such as Fourth-Order Partial Differential Equations (PDEs) and a novel hybrid method combining Sticks filters with Fourth-Order PDE. Quantitative assessment was performed using metrics such as Peak Signal-to-Noise Ratio (PSNR), Mean Squared Error (MSE), Equivalent Number of Looks (ENL), S

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Harris, S., K. S. Rudnicki, and J. E. Haber. "Gene conversions and crossing over during homologous and homeologous ectopic recombination in Saccharomyces cerevisiae." Genetics 135, no. 1 (1993): 5–16. http://dx.doi.org/10.1093/genetics/135.1.5.

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Abstract The pma1-105 mutation reduces the activity of the yeast plasma membrane H(+)-ATPase and causes cells to be both low pH and ammonium ion sensitive and resistant to the antibiotic hygromycin B. Revertants that can grow at pH 3.0 and on ammonium-containing plates frequently arise by ectopic recombination between pma1-105 and PMA2, a diverged gene that shares 85% DNA sequence identity with PMA1. The gene conversion tracts of revertants of pma1-105 were determined by DNA sequencing the hybrid PMA1::PMA2 genes. Gene conversion tracts ranged from 18-774 bp. The boundaries of these replacemen

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Wittenberg, George F., Lorie G. Richards, Lauren M. Jones-Lush, et al. "Predictors and brain connectivity changes associated with arm motor function improvement from intensive robotic practice in chronic stroke." F1000Research 5 (August 31, 2016): 2119. http://dx.doi.org/10.12688/f1000research.8603.1.

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Background and Purpose: The brain changes that underlie therapy-induced improvement in motor function after stroke remain obscure. This study sought to demonstrate the feasibility and utility of measuring motor system physiology in a clinical trial of intensive upper extremity rehabilitation in chronic stroke-related hemiparesis. Methods: This was a substudy of two multi-center clinical trials of intensive robotic arm therapy in chronic, significantly hemiparetic, stroke patients. Transcranial magnetic stimulation was used to measure motor cortical output to the biceps and extensor digitorum c

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Wittenberg, George F., Lorie G. Richards, Lauren M. Jones-Lush, et al. "Predictors and brain connectivity changes associated with arm motor function improvement from intensive practice in chronic stroke." F1000Research 5 (February 28, 2017): 2119. http://dx.doi.org/10.12688/f1000research.8603.2.

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Background and Purpose: The brain changes that underlie therapy-induced improvement in motor function after stroke remain obscure. This study sought to demonstrate the feasibility and utility of measuring motor system physiology in a clinical trial of intensive upper extremity rehabilitation in chronic stroke-related hemiparesis. Methods: This was a substudy of two multi-center clinical trials of intensive robotic and intensive conventional therapy arm therapy in chronic, significantly hemiparetic, stroke patients. Transcranial magnetic stimulation was used to measure motor cortical output to

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Supply, P., A. de Kerchove d'Exaerde, T. Roganti, A. Goffeau, and F. Foury. "In-frame recombination between the yeast H(+)-ATPase isogenes PMA1 and PMA2: insights into the mechanism of recombination initiated by a double-strand break." Molecular and Cellular Biology 15, no. 10 (1995): 5389–95. http://dx.doi.org/10.1128/mcb.15.10.5389.

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Chimeric PMA1::PMA2 sequences, placed under the control of the PMA1 promoter, were constructed by in vivo recombination between a gapped linearized plasmid containing the PMA2 gene and four different fragments of the PMA1 gene. Correct in-frame assembly of the PMA sequences was screened by the expression of the lacZ reporter gene fused to the PMA2 coding region. Restriction and sequencing analysis of 35 chimeras showed that in all cases, the hybrid sequences was obtained as fusions between continuous sequences specific to PMA1 and PMA2, separated by a region of identity. In all but three cases

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Juniar, Eki Rizky, Muhammad Imam Muttaqijn, and Dudung Hadiwijaya. "Job Involvement, Work Facilities, and Work Environment Influence Turnover Intention of Outsourced Employees (PT Angkasa Pura Solusi Integra - Soekarno Hatta Intenational Airport)." Quantitative Economics and Management Studies 5, no. 1 (2024): 181–89. http://dx.doi.org/10.35877/454ri.qems2387.

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This study provides insights into determining the influence of Job Involvement, workplace facilities, and work environment on the Turnover Intention of outsourcing employees at PT. Angkasa Pura Solusi Integra (Soekarno Hatta International Airport). The research employed a quantitative approach with a total of 327 respondents from a population of 1801, which included outsourcing employees such as Avsec, Cleaning Service, Security PMAD, Trolley Collectors, Basket Collectors, and others. Simple random sampling was utilized as the sampling method. The primary data collected in this study involved

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YIN, HONGWEI, XIAOYONG XIAO, XIAOQING WEN, and TIANSHOU ZHOU. "STABILITY OF REGULATORY PROTEIN GRADIENTS INDUCED BY MORPHOGEN DPP IN DROSOPHILA WING DISC." International Journal of Bifurcation and Chaos 23, no. 08 (2013): 1350138. http://dx.doi.org/10.1142/s0218127413501381.

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In the development of Drosophila wing disc, morphogen Dpp, which is a signaling molecule from a local region and disperses into anterior and posterior compartments, builds up a gradient with precise pattern information. Experiments have demonstrated that the key genes (brk, dad, omb and sal) and phosphorylated protein (pMad), which are activated by Dpp signaling molecules and form the gradients of the corresponding proteins of these genes, direct and control the spatial pattern of the wing disc. However, the regulatory network of these genes are in complex and nonlinear interaction with upstre

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Nakatani, Shingo, Takaaki Hato, Yoko Minamoto, and Shigeru Fujita. "Differential Inhibition of Fibrinogen Binding to Agonist-and RGDS Peptide-activated States of GPIIb-IIIa by an anti-GPIIIa Monoclonal Antibody, PMA5." Thrombosis and Haemostasis 76, no. 06 (1996): 1030–37. http://dx.doi.org/10.1055/s-0038-1650703.

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SummaryPlatelet agonists and RGD-containing peptides can convert platelet membrane glycoprotein (GP) Ilb-IIIa from its resting state to an activated state competent to bind soluble fibrinogen. We examined the effects of two anti-GPIIb-IIIa monoclonal antibodies, PMA1 and PMA5, on fibrinogen binding to agonist- and RGD-activated GPIIb-IIIa. PMA1 abolished aggregation of both agonist- and RGDS peptide-activated fixed platelets, and inhibited the binding of 125I-fibrinogen to these platelets almost completely. PMA5 had the same effects on agonist-activated platelets, but had little effect on the

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Ahmed, Mansoor, Faiza Sajjad, Fahim Qazi, Hasan Raza, and Muhammad Mubeen. "Nexus between Public Audit Dimensions and Audit Quality." International Journal of Social Science & Entrepreneurship 4, no. 1 (2024): 57–70. http://dx.doi.org/10.58661/ijsse.v4i1.237.

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This study attempts to examine the dimensions of public audit in the context of audit quality to investigate the association in public sector. SPSS model starts with likert scales consisting of five dimensional structures: trust and confidence, integrity and credibility, independence and impartiality, conflict of interest and professional secrecy & competence and objectivity to measure audit quality. 251 auditors are the respondents of Pakistan Military Accounts Department (PMAD) varying different demographics. The majority of the auditors were satisﬁed with the values and principle set up

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Zivin, Kara, Xiaosong Zhang, Anca Tilea, et al. "Perinatal Psychotherapy Use and Costs Before and After Federally Mandated Health Insurance Coverage." JAMA Network Open 7, no. 8 (2024): e2426802. http://dx.doi.org/10.1001/jamanetworkopen.2024.26802.

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ImportanceInsurance coverage affects health care access for many delivering women diagnosed with perinatal mood and anxiety disorders (PMADs). The Mental Health Parity and Addiction Equity Act (MHPAEA; passed in 2008) and the Patient Protection and Affordable Care Act (ACA; passed in 2010) aimed to improve health care access.ObjectiveTo assess associations between MHPAEA and ACA implementation and psychotherapy use and costs among delivering women overall and with PMADs.Design, Setting, and ParticipantsThis cross-sectional study conducted interrupted time series analyses of private insurance d

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Saeed, A. S. M. Abu, Mst Dilara Pervin, Md Sabuj Ali, Md Ziaul Hassan, Morsheda Akter, and Mst Jebun Susmita Parvin. "Forecasting Monthly Export of Readymade Garments by Removing Seasonal Impact." International Journal of Science and Business 36, no. 1 (2024): 1–8. http://dx.doi.org/10.58970/ijsb.2371.

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Various Bangladeshi authorities release time series data that takes seasonal effects into account. However, no adjusted series is offered. The developed world has completely different conditions since they broadcast seasonally adjusted series. Many seasonal adjustment techniques, such as classical and X-based techniques, are available; however they cannot be used in practice in accordance with Bangladesh's seasonal time series. So here we have executed X-11 and X-12-ARIMA which are known as X-based seasonal adjustment methods and some classical methods like SARIMA and MA to seasonal time serie

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Russell, Shelbi L., Jennie Ruelas Castillo, and William T. Sullivan. "Wolbachia endosymbionts manipulate the self-renewal and differentiation of germline stem cells to reinforce fertility of their fruit fly host." PLOS Biology 21, no. 10 (2023): e3002335. http://dx.doi.org/10.1371/journal.pbio.3002335.

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The alphaproteobacterium Wolbachia pipientis infects arthropod and nematode species worldwide, making it a key target for host biological control. Wolbachia-driven host reproductive manipulations, such as cytoplasmic incompatibility (CI), are credited for catapulting these intracellular bacteria to high frequencies in host populations. Positive, perhaps mutualistic, reproductive manipulations also increase infection frequencies, but are not well understood. Here, we identify molecular and cellular mechanisms by which Wolbachia influences the molecularly distinct processes of germline stem cell

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Hendricks, Emily L., Nicole Linskey, Ireland R. Smith, and Faith L. W. Liebl. "Kismet/CHD7/CHD8 and Amyloid Precursor Protein-like Regulate Synaptic Levels of Rab11 at the Drosophila Neuromuscular Junction." International Journal of Molecular Sciences 25, no. 15 (2024): 8429. http://dx.doi.org/10.3390/ijms25158429.

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The transmembrane protein β-amyloid precursor protein (APP) is central to the pathophysiology of Alzheimer’s disease (AD). The β-amyloid hypothesis posits that aberrant processing of APP forms neurotoxic β-amyloid aggregates, which lead to the cognitive impairments observed in AD. Although numerous additional factors contribute to AD, there is a need to better understand the synaptic function of APP. We have found that Drosophila APP-like (APPL) has both shared and non-shared roles at the synapse with Kismet (Kis), a chromatin helicase binding domain (CHD) protein. Kis is the homolog of CHD7 a

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Bae, Dongryeoul, Keun Seok Seo, Ting Zhang, and Chinling Wang. "Characterization of a Potential Listeria monocytogenes Virulence Factor Associated with Attachment to Fresh Produce." Applied and Environmental Microbiology 79, no. 22 (2013): 6855–61. http://dx.doi.org/10.1128/aem.01006-13.

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ABSTRACTA study to determine the attachment ofL. monocytogenesserotype 4b strain F2365 on vegetables and fruits was conducted. In an initial study, we screened 32 genes encoding surface proteins and lipases of the strain to find highly expressed genes on lettuce leaves. The results showed that transcription levels of LMOf2365_0413, LMOf2365_0498, LMOf2365_0859, LMOf2365_2052, and LMOf2365_2812 were significantly upregulated on lettuce leaves.In silicoanalysis showed that LMOf2365_0859 contains a putative cellulose binding domain. Thus, we hypothesized that this gene may be involved in an attac

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Venkata, Ramalingayya Grandhi, Jayaprakash Tadiparthi, Narender Ganuga, Pradeep Jayarajan, and Ramakrishna Nirogi. "[P2-082]: SUVN-502 (A PURE 5-HT6 ANTAGONIST): PROMISING THERAPEUTIC POTENTIAL FOR PMAD (POST-MENOPAUSE-ASSOCIATED DEMENTIA) AND SMAD (SURGICAL MENOPAUSE-ASSOCIATED DEMENTIA)." Alzheimer's & Dementia 13, no. 7S_Part_13 (2017): P637. http://dx.doi.org/10.1016/j.jalz.2017.06.731.

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Wong, Emily F., Anil K. Saini, Eynav E. Accortt, Melissa S. Wong, Jason H. Moore, and Tiffani J. Bright. "Evaluating Bias-Mitigated Predictive Models of Perinatal Mood and Anxiety Disorders." JAMA Network Open 7, no. 12 (2024): e2438152. https://doi.org/10.1001/jamanetworkopen.2024.38152.

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ImportanceMachine learning for augmented screening of perinatal mood and anxiety disorders (PMADs) requires thorough consideration of clinical biases embedded in electronic health records (EHRs) and rigorous evaluations of model performance.ObjectiveTo mitigate bias in predictive models of PMADs trained on commonly available EHRs.Design, Setting, and ParticipantsThis diagnostic study collected data as part of a quality improvement initiative from 2020 to 2023 at Cedars-Sinai Medical Center in Los Angeles, California. The study inclusion criteria were birthing patients aged 14 to 59 years with

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Ghislain, M., and A. Goffeau. "The pma1 and pma2 H(+)-ATPases from Schizosaccharomyces pombe are functionally interchangeable." Journal of Biological Chemistry 266, no. 27 (1991): 18276–79. http://dx.doi.org/10.1016/s0021-9258(18)55265-0.

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Hato, T., M. Sumida, M. Yasukawa, A. Watanabe, H. Okuda, and Y. Kobayashi. "Induction of platelet Ca2+ influx and mobilization by a monoclonal antibody to CD9 antigen." Blood 75, no. 5 (1990): 1087–91. http://dx.doi.org/10.1182/blood.v75.5.1087.1087.

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Abstract We found that a monoclonal antibody (MoAb) to CD9 antigen, PMA2, induced a rise in cytosolic free calcium concentration ([Ca2+]i) in fura-2-loaded platelets, and we examined whether this response was due to direct action of PMA2 on CD9 antigen. The rise in [Ca2+]i was dependent on the PMA2 concentration, irrespective of the presence or absence of extracellular Ca2+. The role of secreted adenosine diphosphate (ADP) and thromboxane in the [Ca2+]i response to PMA2 was studied using creatine phosphate/creatine phosphokinase (CP/CPK) and aspirin. Combined treatment with CP/CPK and aspirin

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Hato, T., M. Sumida, M. Yasukawa, A. Watanabe, H. Okuda, and Y. Kobayashi. "Induction of platelet Ca2+ influx and mobilization by a monoclonal antibody to CD9 antigen." Blood 75, no. 5 (1990): 1087–91. http://dx.doi.org/10.1182/blood.v75.5.1087.bloodjournal7551087.

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We found that a monoclonal antibody (MoAb) to CD9 antigen, PMA2, induced a rise in cytosolic free calcium concentration ([Ca2+]i) in fura-2-loaded platelets, and we examined whether this response was due to direct action of PMA2 on CD9 antigen. The rise in [Ca2+]i was dependent on the PMA2 concentration, irrespective of the presence or absence of extracellular Ca2+. The role of secreted adenosine diphosphate (ADP) and thromboxane in the [Ca2+]i response to PMA2 was studied using creatine phosphate/creatine phosphokinase (CP/CPK) and aspirin. Combined treatment with CP/CPK and aspirin abolished

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Aspiras, Marcelo B., Karen M. Kazmerzak, Paul E. Kolenbrander, Roderick McNab, Neil Hardegen, and Howard F. Jenkinson. "Expression of Green Fluorescent Protein in Streptococcus gordonii DL1 and Its Use as a Species-Specific Marker in Coadhesion with Streptococcus oralis 34 in Saliva-Conditioned Biofilms In Vitro." Applied and Environmental Microbiology 66, no. 9 (2000): 4074–83. http://dx.doi.org/10.1128/aem.66.9.4074-4083.2000.

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ABSTRACT Streptococcus gordonii is one of the predominant streptococci in the biofilm ecology of the oral cavity. It interacts with other bacteria through receptor-adhesin complexes formed between cognate molecules on the surfaces of the partner cells. To study the spatial organization of S. gordonii DL1 in oral biofilms, we used green fluorescent protein (GFP) as a species-specific marker to identify S. gordonii in a two-species in vitro oral biofilm flowcell system. To drive expression of gfp, we isolated and characterized an endogenous S. gordonii promoter,PhppA, which is situated upstream

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Park, Joo Youn, Jong Wan Kim, Bo Youn Moon, et al. "Characterization of a Novel Two-Component Regulatory System, HptRS, the Regulator for the Hexose Phosphate Transport System in Staphylococcus aureus." Infection and Immunity 83, no. 4 (2015): 1620–28. http://dx.doi.org/10.1128/iai.03109-14.

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Hexose phosphate is an important carbon source within the cytoplasm of host cells. Bacterial pathogens that invade, survive, and multiply within various host epithelial cells exploit hexose phosphates from the host cytoplasm through thehexosephosphatetransport (HPT) system to gain energy and synthesize cellular components. InEscherichia coli, the HPT system consists of a two-component regulatory system (UhpAB) and a phosphate sensor protein (UhpC) that tightly regulate expression of a hexose phosphate transporter (UhpT). Although growing evidence suggests thatStaphylococcus aureusalso can inva

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Vázquez-Carrada, Melissa, Michael Feldbrügge, Dario Rafael Olicón-Hernández, Guadalupe Guerra-Sánchez, and Juan Pablo Pardo. "Functional Analysis of the Plasma Membrane H+-ATPases of Ustilago maydis." Journal of Fungi 8, no. 6 (2022): 550. http://dx.doi.org/10.3390/jof8060550.

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Plasma membrane H+-ATPases of fungi, yeasts, and plants act as proton pumps to generate an electrochemical gradient, which is essential for secondary transport and intracellular pH maintenance. Saccharomyces cerevisiae has two genes (PMA1 and PMA2) encoding H+-ATPases. In contrast, plants have a larger number of genes for H+-ATPases. In Ustilago maydis, a biotrophic basidiomycete that infects corn and teosinte, the presence of two H+-ATPase-encoding genes has been described, one with high identity to the fungal enzymes (pma1, UMAG_02851), and the other similar to the plant H+-ATPases (pma2, UM

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Dorfman, Ruslan, Lillian Glazer, Ulrich Weihe, Mathias F. Wernet, and Ben-Zion Shilo. "Elbow and Noc define a family of zinc finger proteins controlling morphogenesis of specific tracheal branches." Development 129, no. 15 (2002): 3585–96. http://dx.doi.org/10.1242/dev.129.15.3585.

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The elbow (elB) gene encodes a conserved nuclear protein with a single zinc finger. Expression of ElB is restricted to a specific subset of tracheal cells, namely the dorsal branch and the lateral trunks. Stalled or aberrant migration of these branches is observed in elB mutant embryos. Conversely, ElB misexpression in the trachea gave rise to absence of the visceral branch and an increase in the number of cells forming the dorsal branch. These results imply that the restricted expression of ElB contributes to the specification of distinct branch fates, as reflected in their stereotypic patter

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Tominaga, Hiroshi, Shouichi Kawagishi, Hiroyuki Ashida, Yoshihiro Sawa, and Hideo Ochiai. "Structure and Replication of Cryptic Plasmids, pMA1 and pMA2, from a Unicellular Cyanobacterium,Microcystis aeruginosa." Bioscience, Biotechnology, and Biochemistry 59, no. 7 (1995): 1217–20. http://dx.doi.org/10.1271/bbb.59.1217.

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Ivanova, Yu A., Z. A. Temerdashev, I. A. Kolychev, and N. V. Kiseleva. "Determination of polymeric functional additives in diesel fuel by gel penetration chromatography." Аналитика и контроль 25, no. 1 (2021): 53–62. http://dx.doi.org/10.15826/analitika.2020.25.1.003.

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Current article is devoted to the development of a method for determining polymer functional additives and their molecular weight characteristics in diesel fuel by gel penetration chromatography. The objects of the study were solutions of “C5A”, “Maxoil D”, “Detersol”, polymethymethacrylate “D” (PMAD), “Keropur D ”, Antigel “Difron 3319” and “Superantigel” individual additives as well as the diesel fuel produced by the “Kuban Oil and Gas Company - Ilskiy Oil Refinery”, LLC. The conditions for chromatographic separation and determination of polymeric functional additives were determined conside

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Li, Congwei, Lian Duan, and Xinjian Cheng. "Water-soluble chitosan-g-PMAm (PMAA)-Bodipy probes prepared by RAFT methods for the detection of Fe3+ ion." Carbohydrate Polymers 299 (January 2023): 120183. http://dx.doi.org/10.1016/j.carbpol.2022.120183.

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Viegas, C. A., P. B. Sebastião, A. G. Nunes, and I. Sá-Correia. "Activation of plasma membrane H(+)-ATPase and expression of PMA1 and PMA2 genes in Saccharomyces cerevisiae cells grown at supraoptimal temperatures." Applied and environmental microbiology 61, no. 5 (1995): 1904–9. http://dx.doi.org/10.1128/aem.61.5.1904-1909.1995.

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Gordon, Catharina Yanaga. "PMAC-ESP." Work 2, no. 2 (1992): 31–40. http://dx.doi.org/10.3233/wor-1992-2206.

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Serifoglu, C., O. Gungor, and V. Yilmaz. "PERFORMANCE EVALUATION OF DIFFERENT GROUND FILTERING ALGORITHMS FOR UAV-BASED POINT CLOUDS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B1 (June 3, 2016): 245–51. http://dx.doi.org/10.5194/isprsarchives-xli-b1-245-2016.

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Digital Elevation Model (DEM) generation is one of the leading application areas in geomatics. Since a DEM represents the bare earth surface, the very first step of generating a DEM is to separate the ground and non-ground points, which is called ground filtering. Once the point cloud is filtered, the ground points are interpolated to generate the DEM. LiDAR (Light Detection and Ranging) point clouds have been used in many applications thanks to their success in representing the objects they belong to. Hence, in the literature, various ground filtering algorithms have been reported to filter t

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Serifoglu, C., O. Gungor, and V. Yilmaz. "PERFORMANCE EVALUATION OF DIFFERENT GROUND FILTERING ALGORITHMS FOR UAV-BASED POINT CLOUDS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLI-B1 (June 3, 2016): 245–51. http://dx.doi.org/10.5194/isprs-archives-xli-b1-245-2016.

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Digital Elevation Model (DEM) generation is one of the leading application areas in geomatics. Since a DEM represents the bare earth surface, the very first step of generating a DEM is to separate the ground and non-ground points, which is called ground filtering. Once the point cloud is filtered, the ground points are interpolated to generate the DEM. LiDAR (Light Detection and Ranging) point clouds have been used in many applications thanks to their success in representing the objects they belong to. Hence, in the literature, various ground filtering algorithms have been reported to filter t

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