Academic literature on the topic 'PNA Probes'

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Dissertations / Theses on the topic "PNA Probes"

1

Ly, Danith. "Mechanism of electron transfer in double-stranded DNA and PNA-DNA hybrids, and the development of a fluorescence probe for DNA and RNA detection." Diss., Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/30485.

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2

Park, Hyeyoung. "Kinetic and affinity analysis of hybridization reactions between PNA probes and DNA targets using surface plasmon field-enhanced fluorescence spectroscopy (SPFS)." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=976835673.

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Park, Hyeyoung. "Kinetic and affinity analysis of hybridization reactions between PNA probes and DNA targets using surface plasmon fiel enhanced fluorescence spectroscopy (SPFS)." Waabs GCA-Verl, 2005. http://deposit.ddb.de/cgi-bin/dokserv?id=2760979&prov=M&dok_var=1&dok_ext=htm.

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4

Coover, Robert A. "Development of Irreversible Substrate Competitive Probes for PKA Activity." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3907.

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The current environment for drug discovery and disease treatment relies heavily on genomic analysis, structural biology and chemical biology techniques. With the enormous advances in genomic analysis and structural biology, the use of and desire for targeted therapies has increased. However, as more genomic data for cancer disease state pathology becomes available we must ask increasingly difficult questions and even produce new technologies, such as activity-based probes, to answer these questions. In particular, targeted kinase inhibitors for the treatment of cancer has become a mainstay for
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5

Moon, Gyo Sik. "An Algorithm for the PLA Equivalence Problem." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc278922/.

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The Programmable Logic Array (PLA) has been widely used in the design of VLSI circuits and systems because of its regularity, flexibility, and simplicity. The equivalence problem is typically to verify that the final description of a circuit is functionally equivalent to its initial description. Verifying the functional equivalence of two descriptions is equivalent to proving their logical equivalence. This problem of pure logic is essential to circuit design. The most widely used technique to solve the problem is based on Binary Decision Diagram or BDD, proposed by Bryant in 1986. Unfortunate
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6

Oguz, Alaattin. "The Interplay Between Turkish And Hungarian Nationalism: Ottoman Pan-turkism And Hungarian Turanism (1890-1918)." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12606629/index.pdf.

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This thesis dealt with the issues of the emergence of Pan-Turkism in Ottoman Empire and of Pan-Turanism in Hungary between the years 1890 and 1920. The theoretical discussion and literature review related to the subject exhibited that these two nationalisms were possible only when a state bureaucrats and intellectuals try to save the state from collapse and make discussions on the national issues, or when a state elites and noble classes aim to use national ideology for protecting the state from external threats and providing benefits on behalf of national interest. While former suits to Ottom
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7

Cvitkovic, John Peter. "From All-Atom Molecular Mechanics to Coarse- Grained Lattice Models: Computational Approaches to Problems in Protein Biochemistry." Digital WPI, 2019. https://digitalcommons.wpi.edu/etd-dissertations/524.

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Computational simulations of chemical systems play an ever-increasing role in many areas of biochemical research from rational drug design to probing fundamental physiological processes. Depending on the method, a vast array of properties are able to be predicted. Here we report the design and implementation of two methods for investigating diverse problems in protein biochemistry. In order to better understand protein–metal interactions—most importantly for the difficult to model transition metal ions— empirical force field parameters were developed for Pt(II), cisplatin, and other
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8

Hüsken, Nina [Verfasser], Nils [Gutachter] Metzler-Nolte, and Wolfgang [Gutachter] Schuhmann. "Ferrocene-PNA recognition layers : probe design, interfacial and electron transfer studies and DNA detection strategies / Nina Hüsken ; Gutachter: Nils Metzler-Nolte, Wolfgang Schuhmann ; Fakultät für Chemie und Biochemie." Bochum : Ruhr-Universität Bochum, 2012. http://d-nb.info/122317199X/34.

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Bodén, Ida. "Near infrared and skin impedance spectroscopic in vivo measurements on human skin : development of a diagnostic tool for skin cancer." Doctoral thesis, Umeå universitet, Kirurgi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-50605.

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Every year approximately 2800 Swedes are diagnosed with malignant melanoma, the form of cancer that is most rapidly increasing in incidence in the Western world. The earlier we can identify and diagnose a malignant melanoma, the better is the prognosis. In Sweden, 155 000 benign naevi, harmless skin tumours or moles, are surgically excised each year, many of them because melanoma cannot be dismissed by non-invasive methods. The excisions result in substantial medical costs and cause unrest and suffering of the individual patient. For untrained physicians, it is often difficult to make an accur
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10

Mohnani, Stefan. "Synthetic approaches towards modified peptide nucleic acids (PNAs) for biomimetical nanostructured surfaces." Doctoral thesis, Università degli studi di Trieste, 2011. http://hdl.handle.net/10077/4814.

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2009/2010<br>“There is plenty of room at the bottom”. These were the famous words of Richard P. Feynman in 1959 that led to the birth of nanotechnology and nanoscience. Electronic devices based on inorganic semiconductors have been part of our daily lives for the last 60 years. Their miniaturisation has occurred gradually over the years, however, according to Moore’s law the contemporary microelectronic industry’s “top-down” manufacturing technique will soon reach its limits. Therefore, the recent development and increased knowledge of organic semiconductors has led to a tendency to explore al
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