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1

Ray, P. "Une pneumonie lobaire moyenne." Annales françaises de médecine d'urgence 1, no. 1 (December 6, 2010): 45–46. http://dx.doi.org/10.1007/s13341-010-0010-5.

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2

DE VUYST E, DE KEUKELEIRE T, LARIDON E, VANDENBROUCKE F, and LACOR P. "Bilaterale lobaire pneumonie bij een hiv-patiënt." Tijdschrift voor Geneeskunde 62, no. 12 (January 1, 2006): 916–17. http://dx.doi.org/10.2143/tvg.62.12.5002496.

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3

Kané, Bourama. "Aspect épidémiologique des Pneumopathies Aigues Communautaires de l'enfant dans le Service de Pediatrie de l'Hôpital du Mali." Mali Santé Publique 10, no. 1 (July 24, 2020): 64–70. http://dx.doi.org/10.53318/msp.v10i1.1665.

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Introduction : La pneumopathie aiguë, dite communautaire, est définie comme une infection respiratoire basse avec atteinte du parenchyme pulmonaire d'évolution aigue. Elle constitue un problème de santé publique dans le monde. La pneumonie constitue l'infection respiratoire la plus grave chez l'enfant. Le but de ce travail est d'étudier les pneumopathies aiguës communautaires cinq ans après l'introduction du vaccin antipneumococcique treize valences dans la vaccination de routine au Mali. Matériel et méthodes : Il s'agissait d'une étude rétrospective portant sur les dossiers médicaux des enfants dmois à 15 ans ayant été hospitalisés du 01 janvier au 31 décembre 2017 au service de pédiatrie de l'Hôpital du Mali pour gène respiratoire, toux, douleur thoracique. Ont été admis aussi les enfants référés par d'autres structures pour pneumopathie confirmées par une radiographie du thorax. Résultats : Nous avons observé une fréquence globale de 9,46%. La moyenne d'âge était de 3 ans avec des extrêmes d'un mois à 15 ans. Le sex ratio était de 1,44. Le motif d'hospitalisation le plus fréquent était la dyspnée (72.2%). La pneumopathie était associée à la malnutrition aigüe sévère chez 18.3% de nos enfants. Le diagnostic était dominé par la pneumonie franche lobaire aigue (PFLA) (57%) suivie de pleuro-pneumopathie (26.9%) et de broncho-pneumopathie (11.8%). L'association ceftriaxone gentamycine a été utilisée chez 95.7% des enfants. La durée moyenne d'hospitalisation était de 9 jours avec des extrêmes de 0 et 21 jours. Nous avons enregistré 60,2% de taux de guérison et 10,8% de taux de mortalité avec 28.1% chez les moins de 5 ans. Des complications ont été observées chez 28% de nos enfants nécessitant un drainage chirurgical. Conclusion : Le vaccin antipneumococcique a peu d'impact sur l'incidence de la pneumonie chez les enfants de moins de 5 ans. La détermination des causes et l'identification les sérotypes sont nécessaires pour réduire efficacement son incidence.
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4

Lazareva, Ya V., G. B. Sokolova, and I. P. Solovieva. "Caseating pneumonia: computed tomography, differentiated therapy." PULMONOLOGIYA, no. 3 (June 28, 2005): 52–58. http://dx.doi.org/10.18093/0869-0189-2005-0-3-52-58.

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We examined 50 patients with caseating pneumonias of various types and size. We selected CT types of caseating pneumonia (acinous, lobar, lobular, peribronchial), their structure and extension. Computed tomography is found to be the optimal radiological method to detect caseating pneumonic TB forms. Chemotherapy modes for caseating pneumonia patients are presented regarding to its CT types.
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5

Kumar, Surinder, Arti Maria, Sanjeev R. Saigal, and Megha Maheshwari. "Mycoplasma pneumoniae as a cause of non-resolving pneumonia in a neonate." Journal of Medical Microbiology 59, no. 6 (June 1, 2010): 731–32. http://dx.doi.org/10.1099/jmm.0.017491-0.

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Mycoplasma pneumoniae is known to be the chief causative organism for community-acquired non-lobar pneumonia in children of 5–15 years of age. M. pneumoniae as an aetiological agent for pneumonia among neonates and infants has rarely been reported. We report here a case of persistent pneumonia due to M. pneumoniae in a 3-week-old neonate.
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6

Tian, Fang, Li-Ping Chen, Gang Yuan, Ai-Min Zhang, Yu Jiang, and Shuang Li. "Differences of TNF-α, IL-6 and Gal-3 in lobar pneumonia and bronchial pneumonia caused by mycoplasma pneumoniae." Technology and Health Care 28, no. 6 (November 17, 2020): 711–19. http://dx.doi.org/10.3233/thc-192011.

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OBJECTIVE: To investigate the differences of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and galectin-3 concentrations in lobar pneumonia and bronchopneumonia induced by mycoplasma pneumoniae (MP) in children and to explore these related factors predicting the severity of MP. METHODS: A total of 148 children with mycoplasma pneumoniae pneumonia (MPP) and 32 healthy controls were analyzed from March 2017 to August 2018 in our province. Clinical information was collected from the hospitalized MP patients. The 148 patients with MPP were divided into two groups: lobar pneumonia group and bronchial pneumonia group. The 32 healthy children were considered the control group. The concentrations of TNF-α, IL-6 and Gal-3 were examined in the serum of 148 children patients with MPP and 32 healthy children by double-antibody sandwich enzyme-linked immunosorbent assay (ELISA). RESULTS: The TNF-α, IL-6 and Gal-3 levels were obviously higher in both the lobar pneumonia and bronchial pneumonia groups, compared to those in the control group. Furthermore, these levels were significantly higher in the lobar pneumonia group, compared to the bronchial pneumonia group. After treatment, the levels of TNF-α, IL-6 and Gal-3 totally descended during the recovery period. CONCLUSION: There are differences in serum TNF-α, IL-6 and Gal-3 concentrations in lobar pneumonia and bronchial pneumonia caused by MP in children. In general, the TNF-α, IL-6 and Gal-3 levels were significantly higher in the lobar pneumonia group, when compared to the bronchial pneumonia group. This was because most lobar pneumonia cases are much more serious than bronchial pneumonia. Moreover, it has been proven that TNF-α, IL-6 and Gal-3 may play an important role in the pathogenesis development of MPP. At the same time, these are important issues in diagnosing MPP.
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7

Rani, Mamta, Rajesh K. Gupta, and S. Chhibber. "Protection against Klebsiella pneumoniae induced lobar pneumonia in rats with lipopolysaccharide and related antigens." Canadian Journal of Microbiology 36, no. 12 (December 1, 1990): 885–90. http://dx.doi.org/10.1139/m90-153.

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The immunoprotective role of lipopolysaccharide and related antigens from Klebsiella pneumoniae was studied in a lobar pneumonia model developed in rats. Various antigens were obtained by different chemical treatments of the lipopolysaccharide. All these antigens (purified lipopolysaccharide, reduced lipopolysaccharide, lipopolysaccharide – bovine serum albumin complex, and lipid A – bovine serum albumin complex were tested for pyrogenicity and the Shwartzman reaction. The lipopolysaccharide and the various related antigens were pyrogenic and elicited a positive Shwartzman reaction at high concentrations. However, at low concentrations, the same preparations did not show any side effects. All these antigens, on the other hand, were protective against bacterial challenge in Klebsiella pneumoniae induced lobar pneumonia in rats, as the bacterial colonization of lungs in the immunized animals was significantly lower when compared with the controls. The alveolar macrophages from these animals also showed significantly more uptake of Klebsiella pneumoniae as compared with those obtained from control animals. Key words: lipopolysaccharide, vaccine, pneumonia, protection.
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8

Ji, Chenhui, Min Wang, and Xiaocheng Fan. "Water Extract of Gallnut Reduces the Injury of Alveolar Epithelial Cells Induced by Streptococcus pneumoniae by Up-Regulating miRNA-338-3p." Journal of Biomaterials and Tissue Engineering 11, no. 10 (October 1, 2021): 1969–76. http://dx.doi.org/10.1166/jbt.2021.2775.

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Streptococcus pneumoniae (S. pneumoniae) is the primary pathogen causing pneumonia, in addition to lobar pneumonia, meningitis, bronchitis, and other diseases. Inhibiting the apoptosis and inflammation of alveolar epithelial cells is essential for the treatment of pneumonia caused by S. pneumoniae. Traditional Chinese medicine has the characteristics of multiple components, multiple targets, and few adverse reactions. It is recognized by doctors and patients in the treatment of pneumonia and other diseases. We conducted this study to explore the effect of the water extract of gallnut on alveolar epithelial cells affected by S. pneumoniae. Studies have found that the water extract of gallnut can increase the optical density value, Bcl-2 protein expression, IL-10 content, and miRNA-338-3p levels of alveolar epithelial cells affected by S. pneumoniae. Additionally, it can reduce the rate of cell apoptosis, Bax protein expression, and IL-6 content. Further, its effect is dose-dependent: the higher the concentration of gallnut water extract, the more evident its effect on alveolar epithelial cells. Through nano PCR detection, it was found that overexpression of miRNA-338-3p can increase the activity of alveolar epithelial cells affected by S. pneumoniae and promote cell growth. Knockdown of miRNA-338-3p reduced the impact of the water extract of gallnut on the growth of alveolar epithelial cells and the expression of inflammatory factors affected by S. pneumoniae. Therefore, our findings suggest that the water extract of gallnut could inhibit the apoptosis of alveolar epithelial cells affected by S. pneumoniae by up-regulating the expression of miRNA-338-3p.
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9

Yang, Eun Ae, Mi Hyeon Gang, Sun Young You, Jin Hwan Kim, and Jae Ho Lee. "Clinical Characteristics of Children with Lobar Pneumonia Caused byMycoplasma pneumoniae." Pediatric Allergy and Respiratory Disease 22, no. 3 (2012): 256. http://dx.doi.org/10.7581/pard.2012.22.3.256.

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10

Shinozaki, Taro, Kotaro Sasahara, Eri Iwami, Aoi Kuroda, Tatsu Matsuzaki, Takahiro Nakajima, and Takeshi Terashima. "A Case of Influenza B and Mycoplasma pneumoniae Coinfection in an Adult." Case Reports in Infectious Diseases 2018 (November 25, 2018): 1–4. http://dx.doi.org/10.1155/2018/3529358.

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A 19-year-old woman was referred to our hospital because of a persistent fever and cough that lasted for over a week. Influenza B virus infection was diagnosed using the rapid test kit. Initially, the patient was diagnosed with influenza B infection associated with lobar pneumonia and treated with an anti-influenza virus drug and sulbactam/ampicillin. The patient’s fever persisted, and her respiratory condition worsened. On day 5, a computed tomography (CT) scan revealed an extension of the consolidation areas in the left lung and new opacities in the right lung. The antibiotic treatment was changed to meropenem and levofloxacin, and the patient’s physical condition gradually improved. A sputum sample revealed the presence of Mycoplasma pneumoniae-specific DNA. Both influenza B virus and M. pneumoniae infections were confirmed serologically. This was a case of coinfection with influenza B virus and M. pneumoniae in a healthy young woman. The M. pneumoniae pneumonia diagnosis was delayed because the predominant feature observed in the CT scan was dense consolidation. M. pneumoniae should be considered as one of the causative pathogens in influenza coinfection cases with CT scan images presenting dense consolidation.
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11

Chhibber, Sanjay, Sandeep Kaur, and Seema Kumari. "Therapeutic potential of bacteriophage in treating Klebsiella pneumoniae B5055-mediated lobar pneumonia in mice." Journal of Medical Microbiology 57, no. 12 (December 1, 2008): 1508–13. http://dx.doi.org/10.1099/jmm.0.2008/002873-0.

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Klebsiella pneumoniae causes infections in humans especially in immunocompromised patients. About 80 % of nosocomial infections caused by K. pneumoniae are due to multidrug-resistant strains. The emergence of antibiotic-resistant bacterial strains necessitates the exploration of alternative antibacterial therapies, which led our group to study the ability of bacterial viruses (known as bacteriophages or simply phages) to treat mice challenged with K. pneumoniae. Phage SS specific for K. pneumoniae B5055 was isolated and characterized, and its potential as a therapeutic agent was evaluated in an experimental model of K. pneumoniae-mediated lobar pneumonia in mice. Mice were challenged by intranasal (i.n.) inoculation with bacteria (108 c.f.u. ml−1). A single intraperitoneal injection of 1010 p.f.u. ml−1 phage administered immediately after i.n. challenge was sufficient to rescue 100 % of animals from K. pneumoniae-mediated respiratory infections. Administration of the phage preparation 3 h prior to i.n. bacterial challenge provided significant protection in infected mice, while even 6 h delay of phage administration after the induction of infection rendered the phage treatment ineffective. The results of this study therefore suggest that the timing of starting the phage therapy after initiation of infection significantly contributes towards the success of the treatment.
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12

Van der Weide, Hessel, Marian T. Ten Kate, Denise M. C. Vermeulen-de Jongh, Aart Van der Meijden, Rixt A. Wijma, Stefan A. Boers, Mireille Van Westreenen, John P. Hays, Wil H. F. Goessens, and Irma A. J. M. Bakker-Woudenberg. "Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia–Septicemia Model in Rats." Antibiotics 9, no. 3 (March 3, 2020): 109. http://dx.doi.org/10.3390/antibiotics9030109.

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Background: Recent scientific reports on the use of high dose tigecycline monotherapy as a “drug of last resort” warrant further research into the use of this regimen for the treatment of severe multidrug-resistant, Gram-negative bacterial infections. In the current study, the therapeutic efficacy of tigecycline monotherapy was investigated and compared to meropenem monotherapy in a newly developed rat model of fatal lobar pneumonia–septicemia. Methods: A Klebsiella pneumoniae producing extended-spectrum β-lactamase (ESBL) and an isogenic variant producing K. pneumoniae carbapenemase (KPC) were used in the study. Both strains were tested for their in vitro antibiotic susceptibility and used to induce pneumonia–septicemia in rats, which was characterized using disease progression parameters. Therapy with tigecycline or meropenem was initiated at the moment that rats suffered from progressive infection and was administered 12-hourly over 10 days. The pharmacokinetics of meropenem were determined in infected rats. Results: In rats with ESBL pneumonia–septicemia, the minimum dosage of meropenem achieving survival of all rats was 25 mg/kg/day. However, in rats with KPC pneumonia–septicemia, this meropenem dosage was unsuccessful. In contrast, all rats with KPC pneumonia–septicemia were successfully cured by administration of high-dose tigecycline monotherapy of 25 mg/kg/day (i.e., the minimum tigecycline dosage achieving 100% survival of rats with ESBL pneumonia–septicemia in a previous study). Conclusions: The current study supports recent literature recommending high-dose tigecycline as a last resort regimen for the treatment of severe multidrug-resistant bacterial infections. The use of ESBL- and KPC-producing K. pneumoniae strains in the current rat model of pneumonia–septicemia enables further investigation, helping provide supporting data for follow-up clinical trials in patients suffering from severe multidrug-resistant bacterial respiratory infections.
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13

Cherif El Asri, Abad, Ali Akhaddar, Miloudi Gazzaz, Cherkaoui Mandour, Meryem Edderai, Brahim El Mostarchid, and Mohamed Boucetta. "Multiple Brain Abscesses Caused by Streptococcus pneumoniae: Rare Complication of Lobar Pneumonia." Surgical Infections 12, no. 6 (December 2011): 509–10. http://dx.doi.org/10.1089/sur.2011.030.

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14

Sun, Huiming, Wenqing Zhu, Zhengrong Chen, Wei Ji, Chuangli Hao, Zhang Xinxing, Gu Wenjing, and Yuqing Wang. "Community-Acquired Pneumonia Due to Virus and Mycoplasma pneumoniae Infection in Children Younger than 5 Years." Journal of Pediatric Infectious Diseases 14, no. 04 (March 7, 2019): 155–60. http://dx.doi.org/10.1055/s-0039-1683388.

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AbstractThe purpose of this study was to determine the clinical features of viral pathogens and Mycoplasma pneumoniae in children hospitalized with community-acquired pneumonia (CAP). M. pneumoniae infection was diagnosed by both serology and polymerase chain reaction (PCR). Respiratory viruses were detected by direct immunofluorescence or PCR. Medical records of children younger than 5 years diagnosed with 5-day-old CAP were reviewed. Viral pathogens and/or M. pneumoniae were detected in 388 (15.59%) children in the following three groups: viral monoinfection (n = 321), M. pneumoniae with viral coinfection (n = 17), and M. pneumoniae monoinfection (n = 50). M. pneumoniae monoinfection was characterized by older age, fever, higher neutrophil count, and chest X-ray showing lobar consolidation. Wheezing was more common in children with viral infections. Elevated alanine aminotransferase and aspartate aminotransferase were commonly seen in children with Mycoplasma infections. The median symptom duration in children with viral coinfection was shorter than in the other two groups (both p < 0.05). M. pneumoniae and respiratory viruses are important etiologic agents for CAP in children younger than 5 years, with characteristic clinical features. M. pneumoniae and viral coinfection are associated with shorter duration of symptoms before admission.
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15

Yadav, V., S. Sharma, K. Harjai, H. Mohan, and S. Chhibber. "Lipopolysaccharide-mediated protection againstKlebsiella pneumoniae-induced lobar pneumonia: Intranasalvs. intramuscular route of immunization." Folia Microbiologica 50, no. 1 (January 2005): 83–86. http://dx.doi.org/10.1007/bf02931298.

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16

JAFFEY, PAMELA B., PAUL W. ENGLISH, GERALD A. CAMPBELL, SANFORD A. RUBIN, and ABIDA K. HAQUE. "Escherichia Lobar Pneumonia." Southern Medical Journal 89, no. 6 (June 1996): 628–30. http://dx.doi.org/10.1097/00007611-199606000-00017.

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17

Lee, Jae Ho, Eun Ae Yang, Jin Hwan Kim, and Jae Ho Lee. "Environmental and occupational respiratory diseases – 1058. Clinical and diagnostic characteristics of mycoplasma pneumoniae pneumonia in children with lobar pneumonia." World Allergy Organization Journal 6 (2013): P56. http://dx.doi.org/10.1186/1939-4551-6-s1-p56.

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18

Bligh, J., F. X. S. Emmanuel, and M. E. Jones. "Escherichia coli lobar pneumonia." Journal of Infection 21, no. 3 (November 1990): 321–22. http://dx.doi.org/10.1016/0163-4453(90)94221-k.

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19

Singla, Saloni, Kusum Harjai, Om Prakash Katare, and Sanjay Chhibber. "Bacteriophage-Loaded Nanostructured Lipid Carrier: Improved Pharmacokinetics Mediates Effective Resolution ofKlebsiella pneumoniae–Induced Lobar Pneumonia." Journal of Infectious Diseases 212, no. 2 (January 20, 2015): 325–34. http://dx.doi.org/10.1093/infdis/jiv029.

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20

Shan, L. S., Z. J. Wang, N. Chen, X. X. Cai, X. H. Han, L. H. Shu, and Y. X. Shang. "Combined treatment of macrolide antibiotics with glucocorticoid or intravenous immunoglobulin in child Mycoplasma pneumoniae lobar pneumonia." Paediatric Respiratory Reviews 13 (June 2012): S59—S60. http://dx.doi.org/10.1016/s1526-0542(12)70084-2.

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21

Cholongitas, Evangelos, Chrysoula Zouli, Chrysoula Pipili, Konstadinos Katsogridakis, Konstadinos Rellos, and Maria Dasenaki. "Coxiella burnetii and Lobar Pneumonia." Southern Medical Journal 99, no. 11 (November 2006): 1309–10. http://dx.doi.org/10.1097/01.smj.0000247262.11488.7a.

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22

Versluis, P. J., and R. J. S. Lamers. "Lobar pneumonia: An ultrasound diagnosis." Pediatric Radiology 23, no. 7 (November 1993): 561–62. http://dx.doi.org/10.1007/bf02012153.

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23

Pereira, Thiago Scremin Boscolo, Elizandra Moura Santos, Vanessa Belentani Marques, and Eduardo Martini Romano. "Variação morfológica no padrão lobar e nas fissuras dos pulmões." Medicina (Ribeirao Preto Online) 52, no. 3 (November 7, 2019): 261–65. http://dx.doi.org/10.11606/issn.2176-7262.v52i3p261-265.

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Modelo do estudo: Relato de caso. Importância do problema: Lobos e fissuras acessórias nos pulmões podem induzir a erros de interpretação e diagnóstico, além de favorecer a disseminação de patologias como a pneumonia para lobos adjacentes. Dessa forma, a constatação dessas alterações anatômicas pode colaborar em diagnósticos clínicos e procedimentos cirúrgicos. Comentários: Relatamos um caso raro de modificação anatômica nos lobos e fissuras dos pulmões. O pulmão esquerdo exibia um lobo médio acessório e uma fissura horizontal completa. Por outro lado, o pulmão direito apresentava duas fissuras acessórias incompletas situadas inferiormente na face costal do lobo médio. Além disso, observamos que o hilo do pulmão esquerdo continha dois brônquios lobares (superior e inferior), um brônquio lobar acessório e três artérias pulmonares. O conhecimento das variações anatômicas aqui relatadas é fundamental, pois auxiliam os profissionais da saúde nos diagnósticos e nas decisões terapêuticas e cirúrgicas.
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24

Chang, Chia-Jung, Nan-Chang Chiu, Fu-Yuan Huang, Daniel Tsung-Ning Huang, Lung Chang, Ching-Ying Huang, Yen-Hsin Kung, and Hsin Chi. "Predictive value of Thomsen-Friedenreich antigen activation for Streptococcus pneumoniae infection and severity in pediatric lobar pneumonia." Journal of Microbiology, Immunology and Infection 52, no. 4 (August 2019): 571–77. http://dx.doi.org/10.1016/j.jmii.2017.08.011.

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25

GAO, JIAN, BAOZHU YUE, HAITAO LI, RONG CHEN, CHUNLIAN WU, and MILI XIAO. "Epidemiology and clinical features of segmental/lobar pattern Mycoplasma pneumoniae pneumonia: A ten-year retrospective clinical study." Experimental and Therapeutic Medicine 10, no. 6 (October 19, 2015): 2337–44. http://dx.doi.org/10.3892/etm.2015.2818.

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26

A., Nijs, Vandekerkhof J., Cartuyvels R., Magerman K., Mewis A., Peeters V., and Rummens J. "Streptococcus pneumoniae -Infected Aneurysm Extending from a Persistent Lobar Pneumonia: Case Report and Review of the Literature." European Journal of Clinical Microbiology & Infectious Diseases 21, no. 5 (May 1, 2002): 389–92. http://dx.doi.org/10.1007/s10096-002-0724-2.

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27

Feldman, Charles, Jeremy M. Kallenbach, Howard Levy, Jonathan R. Thorburn, Mark D. Hurwitz, and Hendrik J. Koornhof. "Comparison of Bacteraemic Community-Acquired Lobar Pneumonia due to Streptococcus pneumoniae and Klebsiella pneumoniae in an Intensive Care Unit." Respiration 58, no. 5-6 (1991): 265–70. http://dx.doi.org/10.1159/000195943.

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28

Shah, S., Prabin Adhikari, P. Upadhaya, and P. Shah. "Clinical, Bacteriological and Radiological Study of Community Acquired Pneumonia Cases at Tertiary Medical Center in Kathmandu, Nepal." Nepal Medical College Journal 22, no. 1-2 (July 12, 2020): 1–7. http://dx.doi.org/10.3126/nmcj.v22i1-2.29995.

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Community-acquired pneumonia (CAP) remains a common and serious illness, in spite of the availability of potent new antimicrobials and effective vaccines. Despite Nepal being one of the four developing countries accounting for 40.0% of global acute respiratory infections, studies on CAP are limited and the status of adult pneumonia in our community is unknown. This cross-sectional study reviewed the clinical, bacteriological, radiological profile of 100 cases of adult CAP and followed them during the hospital stay for the outcome. The age group with the highest incidence was 60-79 years with females (55.0%) being more affected than males (45.0%). Risk factors were present in 86.0% of cases, chronic obstructive pulmonary disease (COPD), and smoking was the most common, each present in 43.0% of cases. The most common presenting feature was cough (89.80%) followed by sputum production (78.60%), fever (67.30%), shortness of breath (63.30%), chest pain (38.80%), gastrointestinal symptoms (26.50%), altered sensorium (13.30%), and hemoptysis (13.30%). Only 48.0% of patients had leukocytosis. Klebsiella pneumoniae was the most frequent organism isolated (n=4) followed by Pseudomonas aeruginosa (n=3). Fungi were isolated in 3 cases. Lobar pneumonia was seen in 99.0% of cases with the right lower zone being the most commonly involved zone on chest x-ray. Severe pneumonia with CURB-65 (confusion, blood urea nitrogen, respiratory rate, blood pressure, age>65) Score ≥3 was seen in 15.0% of cases. The mean hospital stay was 7.55 days with 28 cases requiring ICU admission and 5 cases of mortality.
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Zhou, Tong, Ying Liu, Tong-Tong Li, and Zhen-Xiang Yu. "Mucoepidermoid Carcinomas Presented as Lobar Pneumonia." Chinese Medical Journal 131, no. 1 (January 2018): 107–8. http://dx.doi.org/10.4103/0366-6999.221277.

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30

Chhibber, Sanjay, and Jaya Bajaj. "Polysaccharide-iron—regulated cell surface protein conjugate vaccine: its role in protection against Klebsiella pneumoniae-induced lobar pneumonia." Vaccine 13, no. 2 (January 1995): 179–84. http://dx.doi.org/10.1016/0264-410x(95)93133-t.

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31

Saklani, Ashish, Ashwani Tomar, Sumala Kapila, Shyam Lal Kaushik, and Anjali Mahajan. "A prospective observational study depicting role of lung ultrasound in pediatric pneumonias." International Journal of Contemporary Pediatrics 8, no. 9 (August 23, 2021): 1566. http://dx.doi.org/10.18203/2349-3291.ijcp20213319.

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Background: Pneumonia is a major cause of morbidity and mortality in children under five years of age. Chest x-ray poses radiation hazard to children and thus an alternative safe imaging modality must be explored for pediatric pneumonias.Methods: This prospective observational study included all children below 18 years of age. Majority of patients were below five years of age. All clinically suspicious patients were subjected to chest x-ray and lung ultrasound (LUS). Chest x-ray was considered as imaging diagnostic standard for pneumonia. Consolidation and dynamic air bronchogram were looked on LUS.Results: A total of 55 patients were included in study with 26 (47.2%) as infants and up to 47 (85.3%) as under five children. Out of 55 cases 32 cases (58.20%) were diagnosed as lobar pneumonia while 23 (41.8%) as bronchopneumonia on chest x-ray. LUS demonstrated high sensitivity and specificity of 90.63% and 100% for lobar pneumonia and 86.96 and 90.63% for bronchopneumonia respectively. Dynamic air bronchogram sign was found in all cases of lobar pneumonia on LUS and with sensitivity of 73.91% in bronchopneumonia.Conclusions: LUS proved itself as highly sensitive and specific modality for detecting consolidation and owing to safe non ionizing nature of ultrasound, it must be considered as an alternative to chest x-ray as an imaging diagnostic tool for pediatric pneumonia.
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32

Storz, Johannes, Xiaoqing Lin, Charles W. Purdy, Vladimir N. Chouljenko, Konstantin G. Kousoulas, Frederick M. Enright, William C. Gilmore, Robert E. Briggs, and Raymond W. Loan. "Coronavirus and Pasteurella Infections in Bovine Shipping Fever Pneumonia and Evans' Criteria for Causation." Journal of Clinical Microbiology 38, no. 9 (2000): 3291–98. http://dx.doi.org/10.1128/jcm.38.9.3291-3298.2000.

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Respiratory tract infections with viruses andPasteurella spp. were determined sequentially among 26 cattle that died during two severe epizootics of shipping fever pneumonia. Nasal swab and serum samples were collected prior to onset of the epizootics, during disease progression, and after death, when necropsies were performed and lung samples were collected. Eighteen normal control cattle also were sampled at the beginning of the epizootics as well as at weekly intervals for 4 weeks. Respiratory bovine coronaviruses (RBCV) were isolated from nasal secretions of 21 and 25 cattle before and after transport. Two and 17 cattle nasally shed Pasteurella spp. before and after transport, respectively. RBCV were isolated at titers of 1 × 103to 1.2 × 107 PFU per g of lung tissue from 18 cattle that died within 7 days of the epizootics, but not from the lungs of the remaining cattle that died on days 9 to 36. Twenty-five of the 26 lung samples were positive for Pasteurella spp., and their CFU ranged between 4.0 × 105 and 2.3 × 109 per g. Acute and subacute exudative, necrotizing lobar pneumonia characterized the lung lesions of these cattle with a majority of pneumonic lung lobes exhibiting fibronecrotic and exudative changes typical of pneumonic pasteurellosis, but other lung lobules had histological changes consisting of bronchiolitis and alveolitis typical of virus-induced changes. These cattle were immunologically naive to both infectious agents at the onset of the epizootics, but those that died after day 7 had rising antibody titers against RBCV andPasteurella haemolytica. In contrast, the 18 clinically normal and RBCV isolation-negative cattle had high hemagglutinin inhibition antibody titers to RBCV from the beginning, while their antibody responses to P. haemolytica antigens were delayed. Evans' criteria for causation were applied to our findings because of the multifactorial nature of shipping fever pneumonia. This analysis identified RBCV as the primary inciting cause in these two epizootics. These viruses were previously not recognized as a causative agent in this complex respiratory tract disease of cattle.
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33

Soleimani Sasani, Mahboubeh, and Fereshteh Eftekhar. "Potential of a Bacteriophage Isolated from Wastewater in Treatment of Lobar Pneumonia Infection Induced by Klebsiella pneumoniae in Mice." Current Microbiology 77, no. 10 (May 25, 2020): 2650–55. http://dx.doi.org/10.1007/s00284-020-02041-z.

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34

Koh, Won Jung, and Joungho Han. "Lobar Pneumonia in an Immunocompetent Adult Patient." Tuberculosis and Respiratory Diseases 58, no. 3 (2005): 291. http://dx.doi.org/10.4046/trd.2005.58.3.291.

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35

ÖZLÜ, Sare Gülfem. "Lobar Pneumonia and Glomerulonephritis: An Unusual Association." Nephrology & Renal Therapy 2, no. 2 (December 30, 2016): 1–3. http://dx.doi.org/10.24966/nrt-7313/100009.

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36

COGGON, D. "Lobar pneumonia: an occupational disease in welders." Lancet 344, no. 8914 (July 1994): 41–43. http://dx.doi.org/10.1016/s0140-6736(94)91056-1.

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37

Wang, Sungho, Sangki Lee, Sungmin Sohn, Sungrock Park, Hyejin Shi, Jaewon Choi, and Won-Woo Seo. "Pulmonary Vein Thrombosis Caused by Lobar Pneumonia." Korean Journal of Medicine 91, no. 3 (December 1, 2016): 283–86. http://dx.doi.org/10.3904/kjm.2016.91.3.283.

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38

DiStasio, Marcello, and Karoly Balogh. "Community-acquired lobar pneumonia encountered at autopsy." IDCases 6 (2016): 34–35. http://dx.doi.org/10.1016/j.idcr.2016.09.006.

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39

Mendes Pedro, Diogo, Maria Cunha, and Tiago Marques. "Lobar expression of SARS-CoV-2 pneumonia." BMJ Case Reports 14, no. 6 (June 2021): e242821. http://dx.doi.org/10.1136/bcr-2021-242821.

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40

Nicolini, Antonello, and Cornelius Barlascini. "Lobar flexible fiberoptic lung lavage: therapeutic benefit in severe respiratory failure in pulmonary alveolar proteinosis and influenza A H1N1 pneumonia." Clinics and Practice 1, no. 3 (July 5, 2011): 53. http://dx.doi.org/10.4081/cp.2011.e53.

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Lobar fiberoptic lung lavage is a well-known procedure used in primary pulmonary alveolar proteinosis (PAP); the use of this procedure has increased in the recent years. This procedure has also been used in other pulmonary diseases such as desquamative interstitial pneumonia with good results. We describe a case of extremely severe respiratory failure due to concurrence of PAP and Influenza A H1N1 virus pneumonia which resolved with the help of this procedure. The patient, a 41- year-old woman, needed less mechanical ventilation after undergoing lobar fiberoptic bronchoscopic lavage. Moreover, a rapid and progressive improvement in the computed tomography of the lungs was observed. Flexibile fiberoptic bronchoscopic lobar lavage is a simple, safe procedure used not only in milder disease, but also in particular severe cases in which the physiological derangement of whole lung lavage would not be tolerated by patient or when extra-corporeal membrane oxygenation is not available.
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41

Fretzayas, Andrew, Maria Moustaki, Polyxeni Nicolaidou, Efthimia Alexopoulou, and Konstantinos N. Priftis. "Transient Elevation of the Ipsilateral Hemidiaphragm Associated with Pneumonia." Canadian Respiratory Journal 18, no. 4 (2011): e66-e67. http://dx.doi.org/10.1155/2011/454052.

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Seventeen children with lobar or segmental pneumonia and ispilateral elevation of the diaphragm are described. These children did not differ significantly with respect to clinical and laboratory findings from their counterparts with pneumonia but without elevation of the hemidiaphragm. The elevation was transient and resolved by the time the repeat chest x-ray was taken six to eight weeks later.
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42

Kashgari, Amna, Mohammed Al Otaibi, and Musaed Alharbi. "Lobar pneumonia in pediatric patient with COVID-19." International Journal of Pediatrics and Adolescent Medicine 7, no. 3 (September 2020): 155–56. http://dx.doi.org/10.1016/j.ijpam.2020.07.002.

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43

LUBSEN, N. "The Course of untreated lobar Pneumonia in Holland." Acta Medica Scandinavica 110, no. 6 (April 24, 2009): 465–75. http://dx.doi.org/10.1111/j.0954-6820.1942.tb06833.x.

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44

Li, Chunrong, Xiujuan Wu, Hehe Qi, Yanwei Cheng, Bing Zhang, Hongwei Zhou, Xiaohong Lv, Kangding Liu, and Hong-Liang Zhang. "Reversible splenial lesion syndrome associated with lobar pneumonia." Medicine 95, no. 39 (September 2016): e4798. http://dx.doi.org/10.1097/md.0000000000004798.

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Tsironi, Maria, Panagiotis Andriopoulos, Spiros Fokas, George Nikokiris, Marina Mantzourani, George Assimakopoulos, and Athanassios Aessopos. "Acute Q fever lobar pneumonia: a case report." Journal of Infection 51, no. 3 (October 2005): e89-e91. http://dx.doi.org/10.1016/j.jinf.2004.09.003.

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46

Ashworth, Mark, Gillian Ross, and C. Loehry. "Lobar pneumonia caused by Haemophilus influenzae type b." British Journal of Diseases of the Chest 79 (January 1985): 95–97. http://dx.doi.org/10.1016/0007-0971(85)90012-9.

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47

Newman, B., and E. Yunis. "Lobar emphysema associated with respiratory syncytial virus pneumonia." Pediatric Radiology 25, no. 8 (November 1995): 646–48. http://dx.doi.org/10.1007/bf02011839.

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48

Hovnanians, Ninel, Osama Alsara, Ahmed N. Mahmoud, Nayan Agarwal, Sanaullah Mojaddedi, R. David Anderson, and Mohammad Khalid Mojadidi. "Cardiac Pneumonia: Acute Mitral Regurgitation Causing Lobar Infiltrate." American Journal of Medicine 130, no. 4 (April 2017): e147-e148. http://dx.doi.org/10.1016/j.amjmed.2016.10.032.

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49

Bleyer, Martina, Marius Kunze, Eva Gruber-Dujardin, and Kerstin Mätz-Rensing. "Spontaneous lung pathology in a captive common marmoset colony (Callithrix jacchus)." Primate Biology 4, no. 1 (March 1, 2017): 17–25. http://dx.doi.org/10.5194/pb-4-17-2017.

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Abstract. Data on spontaneous pathology are substantially scarce for common marmosets, compared to other laboratory animals, but is essential for the interpretation of histological findings in the context of toxicological and experimental studies. Especially if common marmosets are used as experimental animals in respiratory research, detailed knowledge on the spectrum, occurrence, and incidence of spontaneous histopathological pulmonary lesions in this non-human primate species is required. In this study, lung tissue of 638 common marmosets from the marmoset colony of the German Primate Center was examined histologically. The analysis revealed a high incidence of predominantly mild and multifocal interstitial pneumonia (32.99 %) of unknown etiology in most cases. Only few marmosets exhibited lobar pneumonia (1.41 %) and bronchopneumonia (0.94), which were mainly caused by bacterial pathogens such as Bordetella bronchiseptica and Klebsiella pneumoniae. Lung immaturity and atelectasis were common histological findings in newborn marmosets. Typical background lesions included anthracosis (8.15 %), hemosiderosis (1.72 %), extramedullary hematopoiesis (11.6 %), mineralization (10.97 %), and inflammatory cell foci (10.34 %). In addition, three cases of pulmonary arteriopathy (0.47 %) and 1 case of foreign-body granuloma (0.16 %) were detected in the marmoset study cohort. The high prevalence of circulatory disturbances (congestion, edema, hemorrhage) and changes in air content (secondary atelectasis, alveolar emphysema) could partly be explained by euthanasia-related artifacts or agonal changes. The present study provides a comprehensive overview of the range and incidence of spontaneous pulmonary histopathology in common marmosets, serving as valuable reference data for the interpretation of lung lesions in toxicological and experimental marmoset studies.
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S., Srinivasa, and Shruthi Patel. "A study on distribution pattern of lower respiratory tract infections in children under 5 years in a tertiary care centre." International Journal of Contemporary Pediatrics 5, no. 2 (February 22, 2018): 456. http://dx.doi.org/10.18203/2349-3291.ijcp20180535.

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Background: Respiratory infections are the leading cause of mortality in children below 5 years in India as well as worldwide. 16% mortality in children below 5 years is attributed to lower respiratory tract infection. Various factors influence the occurrence of the disease like environmental factors, lack of immunization, malnutrition. Present study was conducted to know the distribution pattern of lower respiratory tract infections, common pathogens associated with respiratory infections and risk factors associated with it. Methods: This study was conducted in Department of Pediatrics, KIMS Bangalore for a period of 1 year from January 2016 to December 2016. Total of 172 children admitted to ward and ICU with history suggestive of respiratory infection were included in the study after excluding congenital heart problems, congenital lung problems and immunodeficiency state.Results: In the present study, male predominance (59.3%) was observed. The incidence of respiratory tract infection was 17.5%. The common pathogen isolated was streptococcus pneumoniae. Most common respiratory infections included bronchopneumonia followed by bronchiolitis, croup, and lobar pneumonia. The common symptoms were cough, fever and hurried breathing. Anemia was observed in majority of them. Conclusion: Respiratory infections if timely managed, the mortality associated with it can be reduced. Pneumonia is a major killer disease in children below 5 years in India. Understanding the symptoms and signs and time of referral to tertiary centre not only reduces the mortality but it also reduces morbidity. So, it is important to create awareness among the health care personnel regarding common age of presentation of various types of respiratory infection and warning sign.
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