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Journal articles on the topic 'Podophyllin'

Author: Grafiati

Published: 12 December 2022

Last updated: 31 July 2025

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1

Dolezal, James F. "Podophyllum resin and podophyllin." Journal of the American Academy of Dermatology 12, no. 4 (1985): 728–30. http://dx.doi.org/10.1016/s0190-9622(85)80174-2.

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2

&NA;. "Podophyllin." Reactions Weekly &NA;, no. 1400 (2012): 34. http://dx.doi.org/10.2165/00128415-201214000-00128.

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3

&NA;. "Podophyllin." Reactions Weekly &NA;, no. 407 (1992): 10. http://dx.doi.org/10.2165/00128415-199204070-00037.

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4

&NA;. "Podophyllin." Reactions Weekly &NA;, no. 929 (2002): 10. http://dx.doi.org/10.2165/00128415-200209290-00035.

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5

&NA;. "Podophyllin." Reactions Weekly &NA;, no. 331 (1990): 10. http://dx.doi.org/10.2165/00128415-199003310-00053.

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6

&NA;. "Podophyllin." Reactions Weekly &NA;, no. 509 (1994): 10. http://dx.doi.org/10.2165/00128415-199405090-00050.

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7

&NA;. "Podophyllin." Reactions Weekly &NA;, no. 1350 (2011): 38. http://dx.doi.org/10.2165/00128415-201113500-00131.

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8

Miller, Robert A. "Podophyllin." International Journal of Dermatology 24, no. 1 (1985): 491–98. http://dx.doi.org/10.1111/j.1365-4362.1985.tb05535.x.

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9

Miller, Robert A. "Podophyllin." International Journal of Dermatology 24, no. 8 (1985): 491–98. http://dx.doi.org/10.1111/j.1365-4362.1985.tb05827.x.

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10

Altaha, Lama. "Evaluation of podophyllin and Trichloroacetic acid for the treatment of genital warts in Iraqi female patients." AL-Kindy College Medical Journal 18, no. 1 (2022): 65–67. http://dx.doi.org/10.47723/kcmj.v18i1.276.

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Background: human paillomavirus infections (genital warts) are the most frequent sexually transmitted viral infections. a wide range of treatment options is available with different efficacy. Objective: To evaluate the efficacy of podophyllin, trichloracetic acid (TCA) in the treatment of genital warts and side effects of them. Subjects and methods: a total of sixty patients with genital warts were randomly selected, 30 in each group, in the Department of Dermatology, medical city for a Duration of 11 months from January 2009 to December 2009 treated with 35 % podophyllin in the tincture of be

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11

Mohammed, Araz. "CRYOTHERAPY VERSUS PODOPHYLLIN IN THE TREATMENT OF GENITAL WARTS IN FEMALES." Journal of Sulaimani Medical College 14, no. 1 (2024): 99–105. https://doi.org/10.17656/jsmc.10455.

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Background Genital warts are a familiar contagious sexually transmitted disease caused by the human papillomavirus. Cryotherapy drives ice crystal formation in the cell, causing the cellular part to hurt and cell death. Podophyllin is an anti-mitotic agent with a direct effect on epithelial cells. Objectives This investigation aimed to evaluate the effectiveness of podophyllin solution versus liquid nitrogen cryotherapy in treating genital warts in females. Patients and methods A randomized clinical trial was conducted on 50 cases of genital warts attending the outpatient dermatology clinic at

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12

Mohanty, K. C. "The Cost Effectiveness of Treatment of Genital Warts with Podophyllotoxin." International Journal of STD & AIDS 5, no. 4 (1994): 253–56. http://dx.doi.org/10.1177/095646249400500405.

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The cost effectiveness of 25% podophyllin resin and 0.5% podophyllotoxin solution in the treatment of genital warts in Genitourinary Medicine Clinic attenders was studied. Although the average treatment cost for a course of podophyllotoxin was more than that for podophyllin resin (£20.75 v. £14.95 respectively) the overall cure rate with podophyllotoxin was 66% as opposed to 34.6% with podophyllin. When the costing of secondary treatment options was considered the cost per patient cured of warts with podophyllin resin was £27.15 compared with £25.73 for podophyllotoxin solution (not significan

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13

&NA;. "Podophyllin poisoning." Reactions Weekly &NA;, no. 325 (1990): 11. http://dx.doi.org/10.2165/00128415-199003250-00052.

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14

Lassus, Allan. "PODOPHYLLIN/PODOPHYLLOTOXIN." Lancet 330, no. 8572 (1987): 1395. http://dx.doi.org/10.1016/s0140-6736(87)91283-9.

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15

Sowmya, PT, AS Paniraj, and Rai KM Lokanatha. "Synthesis, Characterization and Biological Activity of Novel Podophyllotoxin Bearing Pyrimidine Moieties." DER PHARMA CHEMICA 15, no. 6 (2023): 6. https://doi.org/10.4172/0975-413X.15.5.1-6.

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Podophyllotoxin, a naturally occurring aryl tetralin-type lignan obtained from Podophyllin, an ethanolic extract of Podophyllum peltatum L.(syn.P.hexandnum Royle), exhibits marked biological activity as strong antineoplastic drugs and antiviral agents. Chemical transformations performed on podophyllotoxin resulted in analogs which also display potent cytotoxic, antiviral, and immunosuppressive activities. At present, ten novel compounds of podophyllotoxin bearing pyrimidine moieties were synthesized and characterized by 1H and 13C-NMR, elemental analysis, and Mass spectroscopy. All the synthes

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16

Oliveira, Acary Souza Bulle, Leandro Cortoni Calia, Beatriz Hitomi Kiyomoto, Eliane Focaccia Póvoa, Beny Schmidt, and Alberto Alain Gabbai. "Acute necrotizing myopathy and podophyllin toxicity: report of a fatal case." Arquivos de Neuro-Psiquiatria 54, no. 2 (1996): 288–92. http://dx.doi.org/10.1590/s0004-282x1996000200017.

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A 21 year old male ingested podophyllin in a suicide attempt. The disorder was marked by seizures, coma, peripheral neuropathy, renal failure and acute necrotizing myopathy, an unusual finding. The coma and systemic disturbances resolved within three weeks. The myopathy resolved in 7 weeks, demonstrating a high capacity of muscle recuperation. The sensorimotor peripheral neuropathy persisted until the patient's death 9 weeks after the ingestion, due to septicemia. This report confirms the transient central neurotoxicity of podophyllin and persistent peripheral neurotoxicity of podophyllin, and

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17

Hellberg, Dan, Tove Svarrer, Staffan Nilsson, and Jack Valentin. "Self-Treatment of Female External Genital Warts with 0.5% Podophyllotoxin Cream (Condyline®) vs Weekly Applications of 20% Podophyllin Solution." International Journal of STD & AIDS 6, no. 4 (1995): 257–61. http://dx.doi.org/10.1177/095646249500600407.

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Summary: Sixty women with genital warts were randomly allocated to treatment with either weekly application of 20% podophyllin solution or self-treatment with 0.5% podophyllotoxin cream twice daily for three days in weekly intervals. After a maximum of 4 treatment cycles a final assessment was carried out after 3 months. Primary clearance after termination of treatment was 82% for podophyllotoxin and 59% for podophyllin solution. After excluding relapses at the 3-month follow-up, final clearance for podophyllotoxin (71%) was significantly better ( P < 0.05) than that for podophyllin solutio

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18

Srinivasan, Shreya, N. R. Vignesh, G. Sukanya, K. Manoharan, S. Gayathri, and R. N. Raksha. "A study comparing the efficacy of 25% podophyllin resin versus cryotherapy in the treatment of anogenital warts – What is old still holds good!" Indian Journal of Sexually Transmitted Diseases and AIDS 46, no. 1 (2025): 31–36. https://doi.org/10.4103/ijstd.ijstd_54_24.

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Abstract Context: Human papillomavirus types 6 and 11 are the most prevalent strains that produce anogenital warts. Both cryotherapy and podophyllin have approved modalities in the treatment of anogenital warts. Aim: The aim of this study was to determine the treatment outcome following cryotherapy compared to podophyllin in the treatment of anogenital warts. Settings and Design: This was an observational study conducted in a tertiary care hospital. Materials and Methods: All patients diagnosed clinically with anogenital warts were recruited after obtaining informed consent and with due consid

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19

Jantaravinid, Jiraporn, Sukhum Jiamton, Chatchawan Srisawat, Bhoom Suktitipat, and Napatara Tirawanchai. "Expression Pattern of Genes in Condyloma Acuminata Treated with Clinacanthus nutans Lindau Cream versus Podophyllin." Evidence-Based Complementary and Alternative Medicine 2021 (September 17, 2021): 1–9. http://dx.doi.org/10.1155/2021/5579520.

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Clinacanthus nutans Lindua (C. nutans), a strong antiviral traditional medicine, can be used to treat condyloma acuminata (CA) caused by the human papillomavirus (HPV). However, its molecular mechanism for CA elimination is unknown. Herein, we conducted a randomized clinical trial to evaluate the effectiveness of C. nutans and its molecular mechanism compared with podophyllin, the gold standard treatment. Using a randomized block design, six patients were treated with C. nutans and podophyllin for four weeks. Efficacy of drugs was assessed by size reduction of the warts and HPV viral load quan

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20

Holdright, Diana R., and Marjan Jahangiri. "Accidental Poisoning with Podophyllin." Human & Experimental Toxicology 9, no. 1 (1990): 55–56. http://dx.doi.org/10.1177/096032719000900113.

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Podophyllin is available without prescription and is commonly used in the topical treatment of warts. We describe a case of accidental ingestion of podophyllin, mistaken for cough linctus, and its resultant toxicity.

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21

McClean, Hugo, and Siobhan Shann. "A cross-sectional survey of treatment choices for anogenital warts." International Journal of STD & AIDS 16, no. 3 (2005): 212–16. http://dx.doi.org/10.1258/0956462053420130.

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This was a cross-sectional survey that collected data relating to management of anogenital warts (AGW) during a single-patient visit only at genitourinary medicine clinics. Single-agent use of cryotherapy, podophyllotoxin and trichloroacetic acid (TCA) were the most common treatment modalities, accounting for over two-thirds of all modalities used. Podophyllin, alone or in combination with other agents, was used for about 20% of first-line treatments. Podophyllin was included in about 15% of all treatment modalities. Guidelines for the management of AGW continue to recommend the use of podophy

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22

Wardropper, Alison, and Paul Woolley. "Treatment of Anogenital Warts in Genitourinary Clinics in England and Wales." International Journal of STD & AIDS 3, no. 6 (1992): 439–41. http://dx.doi.org/10.1177/095646249200300609.

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A questionnaire on the treatment of anogenital warts was sent to 150 consultants in genitourinary medicine, 78 (52%) were returned completed. A wide range of treatments were used; podophyllin was the commonest first line treatment of multiple penile (60.3%), perianal (57.7%) and vulval (61.5%) warts. Cryotherapy was a popular choice for intrameatal warts (65.3%), small numbers of vulval warts (33.3%) and as second line therapy for penile (35.9%) and perianal (33.3%) warts. Vaginal warts were treated with podophyllin (39.7%) or cryotherapy (29.5%). Various combinations of podophyllin, trichloro

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23

GRAY, J. "Podophyllin and mutagenesis." Journal of the European Academy of Dermatology and Venereology 11 (September 1998): S39. http://dx.doi.org/10.1016/s0926-9959(98)94685-2.

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24

Bargman, Howard. "Podophyllin and Pregnancy." International Journal of Dermatology 32, no. 9 (1993): 691. http://dx.doi.org/10.1111/j.1365-4362.1993.tb04033.x.

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25

Ling, Mark. "Podophyllin and Pregnancy." International Journal of Dermatology 32, no. 9 (1993): 691. http://dx.doi.org/10.1111/j.1365-4362.1993.tb04034.x.

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26

Maatouk, Ismaël. "History of Podophyllin." JAMA Dermatology 152, no. 10 (2016): 1105. http://dx.doi.org/10.1001/jamadermatol.2015.6301.

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27

Jiamton, Sukhum, Pattriya Chanyachailert, Yanisorn Nanchaipruek, et al. "Efficacy and Safety of Clinacanthus nutans Lindau Cream vs. Podophyllin for the Treatment of Adults with Condyloma Acuminata." Evidence-Based Complementary and Alternative Medicine 2022 (June 23, 2022): 1–6. http://dx.doi.org/10.1155/2022/1577716.

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Human papillomavirus (HPV) infection causes condyloma acuminata (CA). Podophyllin is the standard treatment. Clinacanthus nutans Lindau (C. nutans), a medicinal plant, has potent anti-inflammatory and antiviral effects. C. nutans cream is widely used in Thailand to treat the herpes simplex virus. We proposed that C. nutans might also induce CA clearance. There are no studies of C. nutans treatment of CA. This randomized controlled trial at Siriraj Hospital, Thailand, was conducted between January 2018 and December 2019. CA samples were obtained from 10 men with at least two CAs 1 centimeter ap

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28

Sowmya, P. T., A. S. Paniraj, K. M. Lokanatha Rai, and Anitha Sudhir. "Synthesis and biological activity of some new podophyllotoxin bearing pyrimidine moiety." INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY 34, no. 03 (2024): 267. http://dx.doi.org/10.59467/ijhc.2024.34.267.

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Podophyllotoxin (PPT), a naturally occurring aryltetralin-type lignan obtained from Podophyllin, an ethanolic extract of Podophyllum peltatum L. (syn. P. hexandnum Royle), exhibits marked biological activity as strong antineoplastic drugs and antiviral agents. Chemical transformations performed on PPT resulted in analogs which also display potent cytotoxic, antiviral, and immunosuppressive activities. In the present research, ten new compounds of PPTs 2a-l bearing pyrimidine moiety were synthesized by the reaction of PPT (1) with 2-methyl sulphonyl pyrimidines in the presence of tetrahydrofura

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29

Usman, N., K. Udayashankar, S. Subramanian, and S. P. Thyagarajan. "Autoimplantation technique in the treatment of anogenital warts: a clinico-immunological study." International Journal of STD & AIDS 7, no. 1 (1996): 55–56. http://dx.doi.org/10.1258/0956462961917078.

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An autoimplantation technique was adopted in the treatment of 50 cases of anogenital warts and was compared with the conventionally used podophyllin regimen in a matched group of 50 patients. They were assessed with 15 untreated subjects in a control group for the rate of clinical cure after 6 weeks, recurrence after 1 year follow up and for humoral and cell mediated immune responses before and after treatment. In the podophyllin group, 70% of patients were cured after 6 weeks while in autoimplantation, only 44% of patients were cured, and none in the control group had natural remission of war

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30

Oriel, J. D. "Podophyllin--the early days." Sexually Transmitted Infections 73, no. 4 (1997): 290. http://dx.doi.org/10.1136/sti.73.4.290.

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31

&NA;. "Cantharidin/petrolatum/podophyllin/salicylic acid." Reactions Weekly &NA;, no. 1212 (2008): 10. http://dx.doi.org/10.2165/00128415-200812120-00030.

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32

Rothenborg, Hans W. "Podophyllin treatment of anogenital warts." Journal of the European Academy of Dermatology and Venereology 4, no. 2 (2006): 188–89. http://dx.doi.org/10.1111/j.1468-3083.1995.tb00327.x.

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33

Maiti, H., and K. R. Haye. "TOPICAL PODOPHYLLIN FOR GENITAL WARTS." Lancet 330, no. 8562 (1987): 795–96. http://dx.doi.org/10.1016/s0140-6736(87)92523-2.

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34

Marcus, Jeffrey, and Charles Camisa. "Podophyllin Therapy for Condyloma Acuminatum." International Journal of Dermatology 29, no. 10 (1990): 693–98. http://dx.doi.org/10.1111/j.1365-4362.1990.tb03770.x.

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35

Leitner, J., F. Hofbauer, and M. Ackerl. "Vergiftung mit Podophyllin-haltiger Warzentinktur." DMW - Deutsche Medizinische Wochenschrift 127, no. 28/29 (2002): 1516–20. http://dx.doi.org/10.1055/s-2002-32755.

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36

O'Mahony, S., C. Keohane, J. Jacobs, D. O'Riordain, and M. Whelton. "Neuropathy due to podophyllin intoxication." Journal of Neurology 237, no. 2 (1990): 110–12. http://dx.doi.org/10.1007/bf00314673.

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37

Rothenborg, H. "Podophyllin treatment of anogenital warts." Journal of the European Academy of Dermatology and Venereology 4, no. 2 (1995): 188–89. http://dx.doi.org/10.1016/0926-9959(95)93812-z.

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38

BENNETT, RICHARD G., and WILLIAM J. GRIST. "Nasal Papillomas: Successful Treatment With Podophyllin." Southern Medical Journal 78, no. 2 (1985): 224–25. http://dx.doi.org/10.1097/00007611-198502000-00036.

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39

Gorin, F., D. Kindall, and M. Seyd. "Dorsal radiculopathy resulting from podophyllin toxicity." Neurology 39, no. 4 (1989): 607. http://dx.doi.org/10.1212/wnl.39.4.607.

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40

Reynolds, M., M. Murphy, M. A. Waugh, and C. J. N. Lacey. "An Audit of Treatment of Genital Warts: Opening the Feedback Loop." International Journal of STD & AIDS 4, no. 4 (1993): 226–31. http://dx.doi.org/10.1177/095646249300400410.

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An audit of the treatment of patients (100 men and 90 women) presenting with a first episode of anogenital warts to the Genitourinary Medicine Department at Leeds General Infirmary was performed. Treatment of patients was monitored for a period of 6 months from the time of presentation. The management of patients with genital warts lacked a clearly defined strategy and treatment was unselective and poorly monitored. Excluding patients who defaulted, at follow-up 44 (44%) men and 36 (38%) women still had genital warts at 3 months. Of those patients clear of warts at 3 months, the mean time to r

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41

Singh, Ajeet, Ritul Choudhary, and Satyaki Ganguly. "Podophyllin in dermatology: Revisiting a historical drug." Indian Dermatology Online Journal 13, no. 1 (2022): 167. http://dx.doi.org/10.4103/idoj.idoj_225_21.

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42

Kumar, Manish, Arumugasamy Shanmugham, Sivaprakasam Prabha, Bethou Adhisivam, Parameswaran Narayanan, and Niranjan Biswal. "Permanent Neurological Sequelae Following Accidental Podophyllin Ingestion." Journal of Child Neurology 27, no. 2 (2011): 209–10. http://dx.doi.org/10.1177/0883073811415682.

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43

Sholohov, Galina, and Edsel Ing. "Topical podophyllin as a cause of keratopathy." Canadian Journal of Ophthalmology 47, no. 6 (2012): e47-e48. http://dx.doi.org/10.1016/j.jcjo.2012.04.018.

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44

Givens, Melissa L., and Wilfredo Rivera. "Genital burns from home use of podophyllin." Burns 31, no. 3 (2005): 394–95. http://dx.doi.org/10.1016/j.burns.2004.10.020.

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45

Sundharam, J. A. "Is podophyllin safe for use in pregnancy?" Archives of Dermatology 125, no. 7 (1989): 1000–1001. http://dx.doi.org/10.1001/archderm.125.7.1000.

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46

Sanchez, Miguel. "Treatment of Oral Hairy Leukoplakia With Podophyllin." Archives of Dermatology 128, no. 12 (1992): 1659. http://dx.doi.org/10.1001/archderm.1992.04530010095028.

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47

Sanchez, M. "Treatment of oral hairy leukoplakia with podophyllin." Archives of Dermatology 128, no. 12 (1992): 1659. http://dx.doi.org/10.1001/archderm.128.12.1659.

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48

Sundharam, J. A. "Is Podophyllin Safe for Use in Pregnancy?" Archives of Dermatology 125, no. 7 (1989): 1000. http://dx.doi.org/10.1001/archderm.1989.01670190134022.

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49

&NA;. "Podophyllin should not be used in patch testing,." Reactions Weekly &NA;, no. 485 (1994): 5. http://dx.doi.org/10.2165/00128415-199404850-00016.

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50

&NA;. "Electrodesiccation has greater efficacy than cryotherapy and podophyllin." Inpharma Weekly &NA;, no. 730 (1990): 13. http://dx.doi.org/10.2165/00128413-199007300-00030.

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