Relevant bibliographies by topics / Podophyllum

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Academic literature on the topic 'Podophyllum'

Author: Grafiati
Published: 4 June 2021
Last updated: 27 February 2023

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Journal articles on the topic "Podophyllum"

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Dolezal, James F. "Podophyllum resin and podophyllin." Journal of the American Academy of Dermatology 12, no. 4 (April 1985): 728–30. http://dx.doi.org/10.1016/s0190-9622(85)80174-2.

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Chirumbolo, S., A. Conforti, S. Lussignoli, H. Metelmann, and P. Bellavite. "Effects of Podophyllum peltatum compounds in various preparations and dilutions on human neutrophil functions in vitro." British Homeopathic Journal 86, no. 01 (January 1997): 16–26. http://dx.doi.org/10.1016/s0007-0785(97)80005-1.

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AbstractHuman blood neutrophil granulocytes (neutrophils) treated with Podophyllum peltatum L.-derived compounds exhibited an enhanced oxidative response to subsequent challenge with bacterial formyl peptides. This priming effect was concerned with superoxide anion (O2 −) release (respiratory burst). The phenomenon was observed with a potentized preparation containing, among other things, podophyllum extract (Podophyllum compositum), with Podophyllum 4x (final concentration of active principle about 0.025 μg/ml), whereas enhancement of O2 − release was not caused by homoeopathic Podophyllum 12x or other components of the complex homoeopathic preparation. Purified podophyllotoxin had the same effect at doses of 0.1–10 μg/ml, whereas doses higher than 100 μg/ml of podophyllotoxin inhibited the respiratory burst, so that pure toxin showed a typical bi-phasic dose-response curve. Similar effects were obtained with purified colchicine (1–1000 μg/ml), a microtubule-disrupting agent. No priming by a Podophyllum-derived compound was observed on neutrophils stimulated with 50 ng/ml phorbol ester. Further, both potentized podophyllum-derived compounds and pure podophyllotoxin-inhibited cellular adhesion to the serum-coated surface of culture microplates. These results show that low potencies of a drug extract have specific stimulating effects on the activation of neutrophil metabolism. The same stimulating effects are also caused by low doses of the active principle of the drug, which is an inhibitor when used at high doses.
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Liu, C. L., and B. H. Jiao. "LC Determination of Podophyllum Lignans and Flavonoids in Podophyllum emodi Wall.var.chinesis Sprague." Chromatographia 64, no. 9-10 (September 15, 2006): 603–7. http://dx.doi.org/10.1365/s10337-006-0030-8.

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Duke, James A. "Mayapple Lemonade (Podophyllum peltatum L.)." Maine Naturalist 1, no. 2 (1993): 30. http://dx.doi.org/10.2307/3858222.

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Wegener, Andreas. "Schwermut bei einer Gastritis - Podophyllum." Zeitschrift für Klassische Homöopathie 32, no. 03 (April 2, 2007): 95–97. http://dx.doi.org/10.1055/s-2006-938269.

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Chen, Huan, Mingyang Zhang, Ziping Wang, Lingqi Li, Qiqi Li, and Huai Wang. "The Effect of p53-R249S on the Suppression of Hepatocellular Carcinoma Cells Survival Induced by Podophyllum Derivatives." Anti-Cancer Agents in Medicinal Chemistry 20, no. 7 (July 3, 2020): 865–74. http://dx.doi.org/10.2174/1871520620666200218110047.

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Background: Hepatocellular Carcinoma (HCC), the second leading cause of cancer-related mortality with over half a million new cases diagnosed annually in the world, accounts for nearly 70% of cancer deaths in parts of Asia and Africa. Podophyllum, one of the important members of the lignane class of natural products derived from plants in Podophyllum peltatum L., has been shown to suppress tumor growth in various cancers. However, the effects of Podophyllum compounds on HCC and the mechanisms for its tumor-suppressive function remain unknown. Methods: A molecular docking study was employed to the analysis of the interaction between compounds and their targeted proteins. Cell proliferation was measured by MTT assay. Western blot analysis was used to evaluate protein expression. qRT-PCR was performed to assess RNA expression. Results: Molecular docking analysis was consistent with the beneficial effect of fluorine atom substituent in the 3-position of 2-aminopyridine in our previous study. Also, P-3F and D-3F displayed the most potent cytotoxicities against PLC/PRF/5 with p53-R249S and weakest inhibition of L02 (normal liver cell) growth. However, these derivatives had no effect on the suppression of HepG2 (wild-type p53) and Hep3B (p53-null) proliferation significantly. Further study showed that both compounds increase γ-H2AX expression in PLC/PRF/5 cell, along with repression of the c-Myc activation, purportedly by induction of p53 level and transcriptional activation. Conclusion: The results suggested that podophyllum derivatives containing fluorine atom in the 3-position of 2- aminopyridine could inhibit the growth of HCC harboring p53-R249S by restoring the activity of p53 with decreasing the level of c-Myc.
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Kluska, Magdalena, and Katarzyna Woźniak. "Natural Polyphenols as Modulators of Etoposide Anti-Cancer Activity." International Journal of Molecular Sciences 22, no. 12 (June 20, 2021): 6602. http://dx.doi.org/10.3390/ijms22126602.

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Polyphenols are naturally occurring compounds found in abundance in fruits and vegetables. Their health-promoting properties and their use in the prevention and treatment of many human diseases, including cancer, have been known for years. Many anti-cancer drugs are derived from these natural compounds. Etoposide, which is a semi-synthetic derivative of podophyllotoxin, a non-alkaloid lignan isolated from the dried roots and rhizomes of Podophyllum peltatum or Podophyllum emodi (Berberidaceae), is an example of such a compound. In this review, we present data on the effects of polyphenols on the anti-cancer activity of etoposide in in vitro and in vivo studies.
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Xiao, Jian, Xiao-Wei Cong, Gui-Zhen Yang, Ya-Wen Wang, and Yu Peng. "Stereoselective synthesis of a Podophyllum lignan core by intramolecular reductive nickel-catalysis." Chemical Communications 54, no. 16 (2018): 2040–43. http://dx.doi.org/10.1039/c8cc00001h.

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Zhigunov, O. Yu, and I. E. Anishchenko. "PODOPHYLLUM L. AS A PROMISING RARE SHADE-LOVING CULTURE." Izvestia Ufimskogo Nauchnogo Tsentra RAN, no. 2 (July 20, 2018): 32–35. http://dx.doi.org/10.31040/2222-8349-2018-0-2-32-35.

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Avadhani, Kavitha, Padmamalini Mahendradas, Rohit Shetty, and Bhujang K. Shetty. "Topical Podophyllum-induced Toxic Anterior Uveitis." Ocular Immunology and Inflammation 19, no. 2 (March 23, 2011): 118–20. http://dx.doi.org/10.3109/09273948.2010.551446.

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Dissertations / Theses on the topic "Podophyllum"

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Figgitt, David Paul. "Antifungal effects of podophyllum lignans." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258435.

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Baur, Wendy L. "Study of Podophyllotoxin Biosynthesis in Podophyllum species /." Thesis, This resource online, 1990. http://scholar.lib.vt.edu/theses/available/etd-03122009-040904/.

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Crants, James E. "Pollination and pollen limitation in mayapple (Podophyllum peltatum L.) : a nectarless spring ephemeral /." View online, 2008. http://deepblue.lib.umich.edu/bitstream/2027.42/60727/1/jcrants_1.pdf.

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Heyenga, Gerard. "Tissue culture of Podophyllum hexandrum and production of anticancer ligands." Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235985.

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Silva, Cláudia Gontijo. "Tissue culture and phytochemical studies of Podophyllum, Diphylleia and Passiflora species." Thesis, University of Nottingham, 2000. http://eprints.nottingham.ac.uk/28994/.

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Lignans are the most important secondary metabolites known in Podophyllum hexandrum and Diphylleia cymosa. Tissue cultures studies were carried out in order to preserve and increase these germplasms. Somatic embryogenesis in both species was obtained and confirmed histologically. In D. cymosa, somatic embryos were induced from leaf and petiole-derived callus. The formation of abnormal embryos, with fused cotyledons, was influenced by the growth regulators used. Embryo maturation was confirmed histochemically through the identification of starch granules in the cotyledons. Regeneration was dependent on the culture media. Somatic embryogenesis in P. hexandrum was achieved through embryogenic cell suspension cultures from root-derived callus. Organogenesis via adventitious bud formation led to plant regeneration in liquid medium. Phenotypically normal plants were recovered. The regenerant showed the somatic chromosome number of 2n=2x=12, although some chromosomes were morphologically abnormal. The recalcitrance of P. hexandrum towards Agrobacterium-mediated transformation was demonstrated with different strains of both A. tumefaciens and A. rhizogenes. The presence of cytotoxic lignans in P. hexandrum may have a role in the inactivation of the bacteria. Aryltetralin lactone lignans isolated from rhizomes and roots of P. hexandrum and characterized by spectroscopic methods were used as standards in phytochemical studies of D. cymosa. Enzymic hydrolysis of the lignan glycosides, followed by reverse-phase HPLC, allowed the screening of lignans in leaf tissues, calli and cell suspension cultures. The antitumour lignin, podophyllotoxin was detected in young leaves of cultivated plants and. for the first time, in vitro petiole-derived calli. Flavonoids were investigated in leaf extracts of Passiflora edulis, P. incarnate and their somatic hybrids. Fractionation of the crude extracts of P. incarnata and the somatic hybrid SHI led to the isolation of compounds with skeletal type of C-glycosylflavones. Isoorientin was identified in P. edulis. whilst vitexin was found in P. incarnata by TLC. All the somatic hybrids showed similar consistant flavonoid banding profiles. Isoorientin and vitexin were detected in the somatic hybrids. HPLC of the parental species revealed a distinct pattern of flavonoids. Isoorientin was clearly detected in P. edulis, whereas isovitexin was present in both species. The fingerprint patterns of the HPLC separations of the flavonoids were similar in all the somatic hybrids, probably due to the clonal nature of the plants analysed. They appeared to be more closely related to P. incarnata than to P. edulis. However, they also exhibited flavonoids intermediate between those of the parental species. This is the first report of the biosynthesis of isoorientin and isovitexin in these novel somatic hybrids and could provide information about their inheritance.
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Niederhauser, Eric C. "Seed Dispersal of the Forest Herb Podophyllum peltatum by Multiple Vectors." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1429701798.

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Philhower-Gillen, Jennifer R. "The Role of Animals in Maintaining Forest Herb Diversity in Southeast Ohio." Ohio University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1415100392.

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Shiau, Ya Yun, and 蕭雅云. "Tissue Culture of Podophyllum pleianthum and its Secondary Metabolites." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/74592001240421702529.

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碩士
長庚大學
化工與材料工程研究所
92
The medicinal plant is currently one of the hot research topics. Due to the complicated structures of some medicinal materials, most cancer- resisting substances can not be produced by organic synthesis and must be produced by cell culture . Therefore, the objective of this research is to cultivate the plant tissue cells which can secrete an anticancer composition — podophyllotoxin . The materials used in these experiments include podophyllum pleianthum plants from Yang Ming Shan and the callus and suspension cells of the root , steam and leaf from Sitoul offered by the Development Center of Biotechnology. We disinfect the surface of the explant from Yang Ming Shan, cultivate it on a medium based on B5 basal medium supplemented with 1ppm 2,4-D and 0.1ppm kinetin at dark. Callus can thus be greatly produced. The best induced explant is from leaf and its induced rate can reach 92.5%. HPLC analysis indicates that the podophyllotoxin content of the callus from Yang Ming Shan is higher than that from Sitoul. The callus induced from steam and leaf can produce 0.00367% and 0.00341% (g/g) podophyllotoxin, respectively. Among the suspension cells of the root, steam and leaf from the Development Center of Biotechnology, this study shows that the suspension cells induced from root contain a higher content of podophyllotoxin than those induced from steam and leaf. The content of podophyllotoxin induced from root can reach 0.002% (g/g ).
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Kuo, Han-Jung, and 郭翰蓉. "Cloning and Expression of Dirigent Protein from Podophyllum pleianthum Hance." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/56936677970780375355.

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碩士
國立臺灣大學
生化科技學系
99
Podophyllotoxin is an important precursor of anti-tumor drug. Podophylloum pleianthum Hance, an endemic species in Taiwan, is a nature source of podophyllotoxin. The biosynthesis pathway of podophyllotoxin starts from two molecules of coniferyl alcohol radical coupled directionally forming one molecule of (+)-pinoresinol with the involvement of dirigent protein (DP). The cDNA of dirigent protein was cloned from P. pleianthum Hance total RNA by RT-PCR. The length of the dirigent protein cDNA was 579 base pairs and the predicted molecular weight of the dirigent protein was 22 kDa. The cDNA sequence was aligned with DP of Podophyllum peltatum. The identity was 97%. The identity and similarity of amino acid alignment were 96% and 98% respectively. The dirigent protein could not express functionally in recombinant E. coli system. Nicotiana tabacum hairy root for heterologous expression was taken instead. The fluorescent reporter protein ZsYellow was observed by fluorescent microscope. The dimerization reaction of coniferyl alcohol in vitro was performed. Pinoresinol was first converted and was then transferred to other metabolites.
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Chen, Chin-Yi, and 陳靜怡. "Studies on the Tissue Culture of Podophyllum pleianthum Hance and Its Secondary Metaboltes." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/78935979572208269517.

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碩士
國立臺灣大學
農業化學研究所
91
Podophyllum pleianthum Hance has been used for snake bites and healing of wounds in Taiwan. Its secondary metabolite─podophyllotoxin has proven to be an effective anti-tumor agent. Due to slow-growing habit and over-collection, P. pleianthum is listed as an endangered species. The objective of this research is to establish callus and system of suspension cell culture, and to evaluate the content of podophyllotoxin. Leaf, leafstalk, stem (with shoots tip) and root were used as starting material for callus induction. Our results revealed that B5 medium containing 10 mg/L NAA and 0.1 mg/L Kinetin shows good callus induction rate in dark environment. On the other hand, B5 medium containing 15 mg/L NAA and 0.1 mg/L Kinetin shows good callus induction rate in low light condition. Proliferation rate of cells from leaf and stem (with shoots tip) increased 14.2 and 5.4 fold in modified NP medium containing 10 mg/L NAA. The extraction of callus induced from the four different explants was prepared by 3 mL of 80 % methanol under 30 min sonication. It was found that podophyllotoxin can only be detected from the extraction of callus induced from root explant. This metabolite showed a maximum absorption at 205 nm and the retention time at 10.10 min, which was identical to authentic compound of podophyllotoxin. The extraction of cells cultured in a liquid modified NP medium had more complex peaks in HPLC chromatogram than that of callus cultured in a soild B5 medium. These results revealed that some other unknown metabolites were simultaneously produced in the suspension cell culture.
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Books on the topic "Podophyllum"

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Stearn, William T. The Genus Epimedium and Other Herbaceous Berberidaceae (A Botanical Magazine Monograph). Timber Press, Incorporated, 2002.

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Book chapters on the topic "Podophyllum"

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Bährle-Rapp, Marina. "Podophyllum peltatum." In Springer Lexikon Kosmetik und Körperpflege, 434. Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_8064.

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Bowen, I. H., and I. J. Cubbin. "Podophyllum Species." In Adverse Effects of Herbal Drugs 2, 263–73. Berlin, Heidelberg: Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-48906-8_21.

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Khare, C. P. "Podophyllum hexandrum Royle." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1239.

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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott, and R. W. Briddon. "Syngonium podophyllum (Arrowhead plant)." In Encyclopedia of Plant Viruses and Viroids, 2517–18. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_923.

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Chalise, Pratikshya, Yagya Raj Paneru, Hassan Sher, Ikram Ur-Rahman, Wahid Hussain, Arshad Mehmood Abbasi, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Podophyllum hexandrum Royle Berberidaceae." In Ethnobotany of the Himalayas, 1–8. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45597-2_192-1.

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Chalise, Pratikshya, Yagya Raj Paneru, Hassan Sher, Ikram Ur Rahman, Wahid Hussain, Arshad Mehmood Abbasi, Rainer W. Bussmann, and Narel Y. Paniagua-Zambrana. "Podophyllum hexandrum Royle Berberidaceae." In Ethnobotany of the Himalayas, 1561–68. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57408-6_192.

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Khare, C. P. "Podophyllum sikkimensis R. Chatterji & Mukerjee." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_1240.

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Pengelly, Andrew. "Resins and cannabinoids." In The constituents of medicinal plants, 112–22. 3rd ed. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789243079.0007.

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Abstract This chapter provides an overview of resins, which are solid, brittle substances secreted by plants into special ducts, often as a response to damage to the plant by wounding, wind or insect damage. Some major resin and oleo-gum-resin containing plants, such as myrrh, ginger, Capsicum sp. and Podophyllum sp., among others, are presented along with their pharmacological properties. Information on the structures, biosynthesis and medicinal properties of cannabinoids, which are derived from Cannabis sativa, are highlighted.
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Fujii, Yasuo. "Podophyllum spp.: In Vitro Regeneration and the Production of Podophyllotoxins." In Biotechnology in Agriculture and Forestry, 362–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-84071-5_22.

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Watson, Maxine A., Kristin Scott, Jon Griffith, Stephanie Dieter, Cynthia S. Jones, and Sunita Nanda. "The developmental ecology of mycorrhizal associations in mayapple, Podophyllum peltatum, Berberidaceae." In Ecology and Evolutionary Biology of Clonal Plants, 203–20. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-017-1345-0_11.

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Conference papers on the topic "Podophyllum"

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Кузнецова, В. О., and М. П. Китаева. "ALKALOIDS CONTAINED IN PLANTS OF THE GENUS PODOPHYLLUM." In Современные тенденции развития технологий здоровьсбережения. Москва: Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений", 2021. http://dx.doi.org/10.52101/9785870191027_2021_266.

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Oktariza, Lingga Ghufira, Brian Yuliarto, and Suyatman. "Performance of dye sensitized solar cells (DSSC) using Syngonium Podophyllum Schott as natural dye and counter electrode." In 8TH INTERNATIONAL CONFERENCE ON NANOSCIENCE AND NANOTECHNOLOGY 2017 (NANO-SciTech 2017). Author(s), 2018. http://dx.doi.org/10.1063/1.5034553.

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