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Journal articles on the topic 'Point Norfolk, Boston (Mass.)'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2025

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1

Sweet, William V., and Chris Zervas. "Cool-Season Sea Level Anomalies and Storm Surges along the U.S. East Coast: Climatology and Comparison with the 2009/10 El Niño." Monthly Weather Review 139, no. 7 (2011): 2290–99. http://dx.doi.org/10.1175/mwr-d-10-05043.1.

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Abstract Climatologies of sea level anomalies (&gt;0.05 m) and daily-mean storm surges (&gt;0.3 m) are presented for the 1960–2010 cool seasons (October–April) along the East Coast of the United States at Boston, Massachusetts; Atlantic City, New Jersey; Sewells Point (Norfolk), Virginia; and Charleston, South Carolina. The high sea level anomaly and the number of storm surges, among the highest in the last half century during the 2009/10 cool season, are comparable during strong El Niño cool seasons. High numbers of daily storm surges occur in response to numerous East Coast extratrop

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Eyre, Andrew J., Michael B. Stone, and Heidi H. Kimberly. "Point-of-Care Ultrasonography in a Domestic Mass Casualty Incident: The Boston Marathon Experience." Emergency Medicine - Open Journal 2, no. 2 (2016): 32–35. http://dx.doi.org/10.17140/emoj-2-126.

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Catalano, Arielle J., and Anthony J. Broccoli. "Synoptic Characteristics of Surge-Producing Extratropical Cyclones along the Northeast Coast of the United States." Journal of Applied Meteorology and Climatology 57, no. 1 (2018): 171–84. http://dx.doi.org/10.1175/jamc-d-17-0123.1.

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AbstractExtratropical cyclones (ETCs) are responsible for most of the large storm-surge events in the northeastern United States. This study uses the ECMWF atmospheric reanalysis of the twentieth century (ERA-20C) and NOAA tide gauge data to examine the local, regional, and large-scale atmospheric circulation accompanying the 100 largest ETC-driven surge events at three locations along the northeastern coast of the United States: Sewells Point (Norfolk), Virginia; the Battery (New York City), New York; and Boston, Massachusetts. Results from a k-means cluster analysis indicate that the largest

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Demars, B. O. L., D. M. Harper, J. A. Pitt, and R. Slaughter. "Impact of phosphorus control measures on in-river phosphorus retention associated with point source pollution." Hydrology and Earth System Sciences Discussions 2, no. 1 (2005): 37–72. http://dx.doi.org/10.5194/hessd-2-37-2005.

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Abstract. In-river phosphorus retention alters the quantity and timings of phosphorus delivery to downstream aquatic systems. Many intensive studies of in-river phosphorus retention have been carried out but generally on a short time scale (2-4 years). In this paper, monthly water quality data, collected by the Environment Agency of England and Wales over 12 years (1990-2001), were used to model daily phosphorus fluxes and monthly in-river phosphorus retention in the lowland calcareous River Wensum, Norfolk, UK. The effectiveness of phosphorus stripping at two major sewage treatment works was

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Di Benedetto, Laura, Guido Michels, Robert Luben, Kay-Tee Khaw, and Roman Pfister. "Individual and combined impact of lifestyle factors on atrial fibrillation in apparently healthy men and women: The EPIC-Norfolk prospective population study." European Journal of Preventive Cardiology 25, no. 13 (2018): 1374–83. http://dx.doi.org/10.1177/2047487318782379.

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Background Lifestyle factors are important targets for prevention. The cumulative impact of healthy lifestyle on atrial fibrillation in the population has not been quantified. Design Prospective population-based cohort study. Methods Four lifestyle factors (normal weight, currently not smoking, no or moderate alcohol intake, and physically not inactive) were assessed in apparently healthy 21,499 men and women aged 39–79 years participating in the EPIC study in Norfolk, UK. The age and sex-adjusted hazard (95% confidence interval) of hospital admission with a diagnosis of atrial fibrillation du

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Leterme, S. C., and R. D. Pingree. "Structure of phytoplankton (Continuous Plankton Recorder and SeaWiFS) and impact of climate in the Northwest Atlantic Shelves." Ocean Science 3, no. 1 (2007): 105–16. http://dx.doi.org/10.5194/os-3-105-2007.

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Abstract. All marine organisms are affected to some extent by the movement and thermal properties of oceanic currents. However phytoplankton, because of its small size is most directly coupled to the physical environment. The intense hydrodynamic activity observed in the Northwest Atlantic Shelves Province makes this region especially intriguing from the point of view of physical-biological interactions. In the present work, remote sensed data of Sea Surface Height (SSH) anomalies, Sea-surface chlorophyll a concentrations (SeaWiFS), and Sea Surface Temperature (SST) are used to complement the

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Leterme, S. C., and R. D. Pingree. "Structure of phytoplankton (Continuous Plankton Recorder and SeaWiFS) and impact of climate in the Northwest Atlantic Shelves." Ocean Science Discussions 3, no. 5 (2006): 1871–900. http://dx.doi.org/10.5194/osd-3-1871-2006.

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Abstract. All marine organisms are affected to some extent by the movement and thermal properties of oceanic currents. However phytoplankton, because of its small size is most directly coupled to the physical environment. The intense hydrodynamic activity observed in the Northwest Atlantic Shelves Province makes this region especially intriguing from the point of view of physical-biological interactions. In the present work, remote sensed data of Sea Surface Height (SSH) anomalies, Sea-surface chlorophyll a concentrations (SeaWiFS), and Sea Surface Temperature (SST) are used to complement the

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Van, Binh Pham, Linh Nguyen Thuy, Hoa Nguyen Thi Thanh, et al. "Comparison of Novel, Bach Mai Boston Tool (BBT) and the Patient-Generated Subjective Global Assessment (PG-SGA) for Oncology Inpatients." Cancer Control 26, no. 1 (2019): 107327481986376. http://dx.doi.org/10.1177/1073274819863767.

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Oncology inpatients are at high risk of malnutrition. Identification of at risk patients by nutrition screening requires a practical and easy to use tool. The aim of this study was to determine the validity of the Bach Mai Boston Tool (BBT) compared to a ‘gold standard’ full nutrition assessment using the Patient-Generated Subjective Global Assessment (PG-SGA). A cross-sectional study was conducted on 270 oncology inpatients from January to December 2016. Cohen’s Kappa, sensitivity, specificity and ROC analyses were performed. 270 inpatients were included in this study with a mean age of 56.3

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So, Sang-Pil, Won Sun Lee, KiHyeok Ku, Young Ho Shin, and Jae Kwang Kim. "Modified musculofascial lengthening technique for submuscular ulnar nerve transposition in cubital tunnel syndrome." PLOS ONE 20, no. 1 (2025): e0318303. https://doi.org/10.1371/journal.pone.0318303.

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Objective Cubital tunnel syndrome is a common peripheral neuropathy of the upper extremity. Anterior transposition of the ulnar nerve is an established surgical treatment option for this condition. This study aimed to introduce a novel musculofascial lengthening technique that uses only a portion of the flexor-pronator muscle mass for submuscular anterior transposition of the ulnar nerve and investigate its clinical outcomes. Methods We evaluated 28 patients (29 cases; 1 patient had bilateral involvement) diagnosed with cubital tunnel syndrome who were treated with surgical decompression and s

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Baggett, Travis P., Melanie W. Racine, Elizabeth Lewis, et al. "Addressing COVID-19 Among People Experiencing Homelessness: Description, Adaptation, and Early Findings of a Multiagency Response in Boston." Public Health Reports 135, no. 4 (2020): 435–41. http://dx.doi.org/10.1177/0033354920936227.

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People experiencing homelessness are at high risk for coronavirus disease 2019 (COVID-19). In March 2020, Boston Health Care for the Homeless Program, in partnership with city and state public health agencies, municipal leaders, and homeless service providers, developed and implemented a citywide COVID-19 care model for this vulnerable population. Components included symptom screening at shelter front doors, expedited testing at pop-up sites, isolation and management venues for symptomatic people under investigation and for people with confirmed disease, quarantine venues for asymptomatic expo

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Cowan, D. A., K. A. Smolenski, R. M. Daniel, and H. W. Morgan. "An extremely thermostable extracellular proteinase from a strain of the archaebacterium Desulfurococcus growing at 88° C." Biochemical Journal 247, no. 1 (1987): 121–33. http://dx.doi.org/10.1042/bj2470121.

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An organism growing at 88 degrees C that closely resembles Desulfurococcus mucosus produced a single extracellular proteinase. We have purified this enzyme and carried out a preliminary characterization. The proteinase, which is a serine-type enzyme, had a molecular mass of 52,000 Da by SDS/polyacrylamide-gel electrophoresis, but only 10,000-13,000 Da by gel-permeation chromatography. Molecular mass values from sucrose-gradient centrifugation were of the same order as those from SDS/polyacrylamide-gel electrophoresis. It had an isoelectric point of 8.7, and was inhibited by di-isopropyl phosph

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Lee-Lewandrowski, Elizabeth, Daniel Corboy, Kent Lewandrowski, Julia Sinclair, Steven McDermot, and Theodore I. Benzer. "Implementation of a Point-of-Care Satellite Laboratory in the Emergency Department of an Academic Medical Center." Archives of Pathology & Laboratory Medicine 127, no. 4 (2003): 456–60. http://dx.doi.org/10.5858/2003-127-0456-ioapsl.

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Abstract Context.—Emergency department (ED) overcrowding has reached crisis proportions in the United States. Many hospitals are seeking to identify process reengineering efforts to reduce crowding and ED patient length of stay (LOS). Objectives.—To investigate the impact of a point-of-care testing (POCT) satellite laboratory in the ED of a large academic medical center. Setting.—The ED of the Massachusetts General Hospital, Boston, Mass. Design and Outcome Measures.—Evaluation of physician satisfaction, turnaround time (TAT), and ED LOS before and after implementation of a POCT laboratory. ED

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Lowry, Kristen C., Judy A. Estroff, and Reza Rahbar. "The Presentation and Management of Fibromatosis Colli." Ear, Nose & Throat Journal 89, no. 9 (2010): E4—E8. http://dx.doi.org/10.1177/014556131008900902.

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We conducted a systematic chart review to identify all in-fants with fibromatosis colli who had been seen at Children's Hospital in Boston from January 1999 through December 2004. We found 7 such cases, which involved 4 boys and 3 girls, aged 1 to 3.5 weeks at presentation. We compiled information on each patient's birth history, presenting signs and symptoms, significant medical history, imaging findings, management, follow-up, and outcome. Six of the 7 patients presented with a neck mass, and the remaining patient presented with neck “fullness.” Five patients developed torticollis at some po

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Zapaishchykova, Anna, Divyanshu Tak, Zezhong Ye, et al. "IMG-06. IMAGING-BASED, TEMPORALIS MUSCLE THICKNESS AS A BIOMARKER IN CHILDREN WITH GLIOMAS." Neuro-Oncology 26, Supplement_4 (2024): 0. http://dx.doi.org/10.1093/neuonc/noae064.343.

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Abstract BACKGROUND Sarcopenia, or lean muscle loss, causes morbidity and early mortality in pediatric cancer patients and survivors. Sarcopenic patients who are also obese have a particularly morbid metabolic condition that cannot be identified by body mass index (BMI) alone. Temporalis muscle thickness (TMT) on T1-weighted MRI provides a direct assessment of lean muscle mass. In this study, we determined how TMT was associated with nutritional and survival outcomes in children with gliomas using an automated deep-learning pipeline that calculates TMT on MRI and provides age-and sex-specific

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Paladin, Nicola. "Modes and Moves of Protest." Review of International American Studies 12, no. 2 (2019): 103–18. http://dx.doi.org/10.31261/rias.7376.

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The role of mass protest has been recurrently central yet controversial in the American culture. Central because American history presents a constellation of significant collective protest movements, very different among them but generally symptomatic of a contrast between the people and the state: from the 1775 Boston Massacre and the 1787 Shays’s Rebellion, to the 1863 Draft Riots, but also considering the 1917 Houston Riot or anti-Vietnam war pacifist protests. Controversial, since despite—or because of—its historical persistence, American mass protest has generated a media bias which label

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Lentjes, Marleen A. H., Ruth H. Keogh, Ailsa A. Welch, et al. "Longitudinal associations between marine omega-3 supplement users and coronary heart disease in a UK population-based cohort." BMJ Open 7, no. 10 (2017): e017471. http://dx.doi.org/10.1136/bmjopen-2017-017471.

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ObjectivesAssess the association between marine omega-3 polyunsaturated fatty acid (n-3 PUFA) intake from supplements, mainly cod liver oil, and coronary heart disease (CHD) mortality.DesignProspective cohort study, with three exposure measurements over 22 years.SettingNorfolk-based European Prospective Investigation into Cancer (EPIC-Norfolk, UK).Participants22 035 men and women from the general population, 39–79 years at recruitment.ExposureSupplement use was assessed in three questionnaires (1993–1998; 2002–2004; 2004–2011). Participants were grouped into non-supplement users (NSU), n-3 PUF

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Offner, G. D., P. Brecher, W. B. Sawlivich, C. E. Costello, and R. F. Troxler. "Characterization and amino acid sequence of a fatty acid-binding protein from human heart." Biochemical Journal 252, no. 1 (1988): 191–98. http://dx.doi.org/10.1042/bj2520191.

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The complete amino acid sequence of a fatty acid-binding protein from human heart was determined by automated Edman degradation of CNBr, BNPS-skatole [3′-bromo-3-methyl-2-(2-nitrobenzenesulphenyl)indolenine], hydroxylamine, Staphylococcus aureus V8 proteinase, tryptic and chymotryptic peptides, and by digestion of the protein with carboxypeptidase A. The sequence of the blocked N-terminal tryptic peptide from citraconylated protein was determined by collisionally induced decomposition mass spectrometry. The protein contains 132 amino acid residues, is enriched with respect to threonine and lys

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Dai, Jun, Yafen Guo, Quan Zhou, Xiang-Jie Duan, Jinhua Shen, and Xueqing Zhang. "The relationship between red cell distribution width, serum calcium ratio, and in-hospital mortality among patients with acute respiratory failure: A retrospective cohort study of the MIMIC-IV database." Medicine 103, no. 15 (2024): e37804. http://dx.doi.org/10.1097/md.0000000000037804.

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To investigate the impact of RDW/CA (the ratio of red cell distribution width to calcium) on in-hospital mortality in patients with acute respiratory failure (ARF). This retrospective cohort study analyzed the data of 6981 ARF patients from the Medical Information Mart for Intensive Care (MIMIC-IV) database 2.0. Critically ill participants between 2008 and 2019 at the Beth Israel Deaconess Medical Center in Boston. The primary outcome of interest was in-hospital mortality. A Cox proportional hazards regression model was used to determine whether the RDW/CA ratio independently correlated with i

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Gubergrits, N. B. "Frequency, clinical picture, diagnosis, and differential diagnosis of the pathology of the digestive tract (esophagus, stomach, and bowel) in IgG4-related disease (autoimmune pancreatitis)." Herald of Pancreatic Club 59, no. 2 (2023): 26–34. http://dx.doi.org/10.33149/vkp.2023.02.05.

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Despite the publication of European guidelines for the diagnosis and treatment of IgG4-related disease (IgG4-RD), this problem is very complicated from a practical point of view. There are many publications about autoimmune pancreatitis and liver and biliary tract lesions in IgG4-RD, but the data on the digestive tract lesions are not sufficient. Gastrointestinal manifestations of IgG4-RD are considered to be rare or very rare. IgG4-RD presenting as esophageal lesions is rare condition. Only single clinical cases are available. I. Obiorah et al. reported the highest number of cases of Ig

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Lin, Chien-Wen, Jen-Cheng Wang, Bo-Yan Zhong, et al. "Lie symmetry analysis of the effects of urban infrastructures on residential property values." PLOS ONE 16, no. 8 (2021): e0255233. http://dx.doi.org/10.1371/journal.pone.0255233.

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Due to the complexity of socio-economic-related issues, people thought of housing market as a chaotic nucleus situated at the intersection of neighboring sciences. It has been known that the dependence of house features on the residential property value can be estimated employing the well-established hedonic regression analysis method in teams of location characteristic, neighborhood characteristic and structure characteristic. However, to further assess the roles of urban infrastructures in housing markets, we proposed a new kind of volatility measure for house prices utilizing the Lie symmet

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Chou, Ting-Chao. "Abstract LB_B20: The Unity Theory of One: The dynamic algorithm of mass action law for drug and biosimilar digital evaluation/simulation in molecules, cells, and organs, regardless of units, physical states, and mechanisms." Molecular Cancer Therapeutics 22, no. 12_Supplement (2023): LB_B20. http://dx.doi.org/10.1158/1535-7163.targ-23-lb_b20.

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Abstract Mathematical analysis of mass-action law (MAL) of the intermediate-forming system analysis led to the general median-effect equation (MEE) for action dynamics that determines potency (Dm, median-effect dose, and dynamic order [m, the shape of dose-effect-curve (DEC) where m=1, &gt;1, &lt;1 indicate hyperbolic, sigmoidal and flat sigmoidal, respectively]; the combination index equation (CIE) for interaction that quantifies synergism (CI&lt;1), additive effect (CI=1) and antagonism (CI&gt;1); and the dose-reduction index equation (DRIE) for interaction consequences, wher

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Hingorani, Sunil R. "Abstract IA019: Stromal-epithelial co-evolution and complicity in pancreas cancer." Cancer Research 82, no. 22_Supplement (2022): IA019. http://dx.doi.org/10.1158/1538-7445.panca22-ia019.

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Abstract The robust desmoplasia of PDA is its distinguishing feature and non-malignant components constitute the bulk of the tumor mass. This stromal reaction includes myofibroblasts, inflammatory fibroblasts, endothelial cells, pericytes, and various immune-cell subsets, all embedded within a dense and complex extracellular matrix (ECM). Dominated by non-malignant cells, the mutated epithelium must therefore combat, cooperate with, or coopt the surrounding cells and signaling processes in its microenvironment. It is proposed that an invasive PDA represents the coordinated evolution of maligna

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Nichols, Amy R., Sheryl L. Rifas-Shiman, Karen M. Switkowski, et al. "History of Infertility and Midlife Cardiovascular Health in Female Individuals." JAMA Network Open 7, no. 1 (2024): e2350424. http://dx.doi.org/10.1001/jamanetworkopen.2023.50424.

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ImportanceFertility status is a marker for future health, and infertility has been associated with risk for later cancer and diabetes, but associations with midlife cardiovascular health (CVH) in female individuals remain understudied.ObjectiveTo evaluate the association of infertility history with CVH at midlife (approximately age 50 years) among parous individuals.Design, Setting, and ParticipantsProject Viva is a prospective cohort study of pregnant participants enrolled between 1999 and 2002 who delivered a singleton live birth in the greater Boston, Massachusetts, area. Infertility histor

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Cummins, Katherine A., and Ronny Drapkin. "Abstract A011: Assessing pro-tumorigenicity of the aging microenvironment in a murine ovarian cancer model." Cancer Research 84, no. 22_Supplement (2024): A011. http://dx.doi.org/10.1158/1538-7445.tumbody-a011.

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Abstract Over 70% of high-grade serous ovarian cancer (HGSOC) patients are diagnosed after age 55 and the average patient who succumbs to HGSOC is 70 years old. Despite this, the majority of ovarian cancer studies, and cancer studies generally, utilize young mice that are more representative of human children. This approach overlooks age as a variable, despite its status as a top risk factor for cancer. Our preliminary studies reveal tumor burden and disease severity is significantly higher in aged mice compared to young animals. We have developed an epithelial cell line derived from C57BL/6 o

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Dyachenko, L., E. Syvachenko, and T. Syvyk. "Contents of the microflora of the intestine, retention and productivity of broiler chickens in accordance with different types and quantities of the acidifier." 145, no. 2 (December 27, 2018): 14–23. http://dx.doi.org/10.33245/2310-9289-2018-145-2-14-23.

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In two scientific-field experiments with broiler chicken cross-breeding ”Kobb-500", the goal was set to learn the influence of different dosages, forms and types of feeding the acidifier FRA LBB DRY onto the contents of the microflora of intestine, retention and productivity of broiler chickens. The first experiment was done using three groups-analogs of broiler chickens, 46 birds per group. The broiler chickens of the first group were the control group. This group was fed a regular mixed feed. The second and third groups were fed the same mixed feed with an addition of the acidifier of FRA LB

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Grunberg, Nil, Jiani Qian, Joseph Tam, et al. "Abstract A025: Extracellular-vesicles from the peri-prostatic adipose tissue of obese, but not lean, men promote prostate cancer aggressivity." Cancer Research 84, no. 22_Supplement (2024): A025. http://dx.doi.org/10.1158/1538-7445.tumbody-a025.

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Abstract Prostate cancer (PC) affects 1-in-8-men and obesity, termed a global epidemic by the WHO, affects 1-in-3. Obesity is the largest modifiable cancer risk-factor: every five-point increase in body-mass index increases risk of fatal PC by almost 10% and shortens the time to development of treatment-refractory metastatic disease. Further, weight gain is a common side-effect of mainstay androgen-deprivation therapy. The peri-prostatic adipose tissue (PPAT) is an important component of the PC tumor microenvironment (TME). PPAT volume is associated with increased PC lethality/reduced therapy

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Burchard, Paul R., Luis I. Ruffolo, Nicholas A. Ullman, et al. "Abstract PO024: Combination therapy with PXS-5505 improves chemotherapeutic efficacy and reduces myeloid immune suppression in murine cholangiocarcinoma – a novel therapeutic strategy for clinical translation." Clinical Cancer Research 28, no. 17_Supplement (2022): PO024. http://dx.doi.org/10.1158/1557-3265.liverca22-po024.

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Abstract Introduction: Despite growing prevalence, 5-year survival for cholangiocarcinoma remains poor due to an immunosuppressive fibroinflammatory stroma, featuring abundant collagen and cancer-associated fibroblasts. Lysyl oxidases (LOX) consist of 5 secreted enzymes that catalyze collagen cross-linking, resulting in increased tumor stroma density and facilitate immune evasion. Here, we present our findings of pan-LOX inhibition with a novel orally dosed agent (PXS-5505) in a murine model of CCA. Methods: Immunohistochemistry (IHC) analysis was performed on a human tissue macro-array of CCA

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Carpenter, Chris. "Proposed Methods Accelerate Permanent CO2-Storage Process." Journal of Petroleum Technology 76, no. 07 (2024): 105–7. http://dx.doi.org/10.2118/0724-0105-jpt.

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_ This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 215352,“ Accelerating the Permanent CO2 Storage Process: A Safer and Faster Route to Net Zero,” by Shubham Mishra, SPE, Boston Consulting Group. The paper has not been peer reviewed. _ The complete paper proposes two methods of accelerating the solidification (or mineralization) of CO2 in subsurface conditions, thus reducing the time required in the CO2 storage process. It also reviews industry and academic works devoted to the subject. Introduction Two main concerns with CO2 storage in subsurfac

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Rao, Shalini V., Lisa Young, Danya Cheeseman, et al. "Abstract C076: New insights into the role of FOXA1- HNF4 axis in pancreatic cancer." Cancer Research 84, no. 2_Supplement (2024): C076. http://dx.doi.org/10.1158/1538-7445.panca2023-c076.

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Abstract Despite recent advances in the treatment of pancreatic adenocarcinoma (PDAC), the median survival remains &lt;12 months. Patients typically present with late-stage disease and have limited treatment options. Therefore, there is an immediate need for the generation of new and innovative therapeutic targets. Little is known about the role of pioneer factors such as FOXA1 and their interaction partners in a PDAC context. Inspired by literature reports implicating FOXA1 and GATA5/GATA6 in regulating pancreatic cancer resistance and metastasis, our study hypothesised the possibility of

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Sampson, Michael, Allan Clark, Max Bachmann, et al. "Effects of the Norfolk diabetes prevention lifestyle intervention (NDPS) on glycaemic control in screen-detected type 2 diabetes: a randomised controlled trial." BMC Medicine 19, no. 1 (2021). http://dx.doi.org/10.1186/s12916-021-02053-x.

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Abstract Background The purpose of this trial was to test if the Norfolk Diabetes Prevention Study (NDPS) lifestyle intervention, recently shown to reduce the incidence of type 2 diabetes in high-risk groups, also improved glycaemic control in people with newly diagnosed screen-detected type 2 diabetes. Methods We screened 12,778 participants at high risk of type 2 diabetes using a fasting plasma glucose and glycosylated haemoglobin (HbA1c). People with screen-detected type 2 diabetes were randomised in a parallel, three-arm, controlled trial with up to 46 months of follow-up, with a control a

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Chandra, Alvin, Michael H. Picard, Shi Huang, et al. "Impact of Vitamin D3 Versus Placebo on Cardiac Structure and Function: A Randomized Clinical Trial." Journal of the American Heart Association, October 26, 2022. http://dx.doi.org/10.1161/jaha.121.025008.

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Background Vitamin D supplementation leads to regression of left ventricular (LV) hypertrophy and improves LV function in animal models. However, limited data exist from prospective human studies. We examined whether vitamin D supplementation improved cardiac structure and function in midlife/older individuals in a large randomized trial. Methods and Results The VITAL (Vitamin D and OmegA‐3 Trial) was a nationwide double‐blind, placebo‐controlled randomized trial that tested the effects of vitamin D3 (2000 IU/d) and n−3 fatty acids (1 g/d) on cardiovascular and cancer risk in 25 871 individual

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Vinik, Aaron, Etta Vinik, Ying-Chuen Lai, et al. "Imbalance in Cardiac Autonomic Nervous System Mediates Fatigue." Medical Research Archives 10, no. 2 (2022). http://dx.doi.org/10.18103/mra.v10i2.2659.

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Aims To explore the impact of the autonomic nervous system function in “disease-free” people for testing and appropriate therapies in different age-groups. Methods Seventy-five disease-free volunteers who participated in a previous study were randomly selected from five age-groups (30-79 years) for a cross/sectional study to assess the impact of fatigue on cardiac/autonomic function by analysis of heart rate variability (HRV) and measures of cognitive and physical fatigue on quality-of-life-fatigue (QOLF) scores. Written informed consent was obtained and protocol approved. To induce fatigue, t

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Baranowski, Bradley, Willem T. Peppler, and Rebecca EK MacPherson. "Acute Exercise Rescues Cortex BDNF Signaling In High Fat Fed Male Mice." FASEB Journal 31, S1 (2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.lb707.

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High fat diet induced obesity and insulin resistance have been directly implicated in the neuropathology of Alzheimer's disease. It is thought that high fat diets induce a reduction in neuronal plasticity through a reduction in the neurotrophin, brain‐derived neurotrophic factor (BDNF). Previous work has demonstrated that acute exercise can reverse high fat diet induced alterations in cortices from obese mice, however the underlying mechanisms remain unknown. The purpose of this study was to determine the effects of a single bout of exercise on BDNF content and signaling in the prefrontal cort

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Dawson-Hughes, Bess, Elsa M. Konieczynski, and Lisa Ceglia. "Obesity may extend the time required to reach a steady-state 25-hydroxyvitamin D level after initiating vitamin D supplementation." JBMR Plus, February 8, 2025. https://doi.org/10.1093/jbmrpl/ziaf030.

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Abstract Obesity is known to influence the circulating 25-hydroxyvitamin D [25(OH)D] level but less is known about whether it influences the time required to reach a stable 25(OH)D level after initiating vitamin D supplementation. This observational study was done to investigate whether body mass index (BMI) modified the time required to reach a steady-state 25(OH)D level in response to vitamin D supplementation. Participants in the Boston STOP IT study who were treated for 12 months with 700 IU of vitamin D3 and 500 mg of calcium daily and had 25(OH)D measures at 0, 6, and 12 months, were inc

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Piper, Melanie. "Blood on Boylston: Digital Memory and the Dramatisation of Recent History in Patriots Day." M/C Journal 20, no. 5 (2017). http://dx.doi.org/10.5204/mcj.1288.

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IntroductionWhen I saw Patriots Day (Berg 2016) at my local multiplex, a family entered the theatre and sat a few rows in front of me. They had a child with them, a boy who was perhaps nine or ten years old. Upon seeing the kid, I had a physical reaction. Not quite a knee-jerk, but more of an uneasy gut punch. ‘Don't you know what this movie is about?’ I wanted to ask his parents; ‘I’ve seen Jeff Bauman’s bones, and that is not something a child should see.’ I had lived through the 2013 Boston Marathon bombing and subsequent manhunt, and the memories were vivid in my mind as I waited for the m

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Bigornia, Sherman, Tammy Scott, Brian Barth, Jose M. Ordovas, and Katherine Tucker. "Associations of Mediterranean-style Diet Adherence with Circulating Sphingolipid Patterns (P18-004-19)." Current Developments in Nutrition 3, Supplement_1 (2019). http://dx.doi.org/10.1093/cdn/nzz039.p18-004-19.

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Abstract Objectives Building evidence suggests that greater adherence to a Mediterranean-style diet (MD) may reduce the risk of cardiovascular disease, type 2 diabetes, and dementia. However, our understanding of the biological mechanisms explaining these associations is limited. Altered sphingolipid metabolism (e.g., increased ceramides, glycosyl- and lactosyl-ceramides, sphingoid bases, and sphingomyelin (SM)) has been implicated in the development of chronic health conditions. We aimed to quantify the impact of MD adherence on circulating patterns of sphingolipid metabolites. Methods Cross-

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Anne, Marie D'Arcy. "'Li anemis meismes: Satan and Synagogue in La Queste del Saint Graal'." September 9, 1997. https://doi.org/10.2307/43630063.

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The identification of the Jewish people with ‘serpens antiquus qui vocatur Diabolus et Satanas’[1] is a cherished theme of medieval polemicists, and a close examination of the Queste del Saint Graal (c<em>.</em> 1220) reveals evidence of such an association on the part of the author. While reference is explicitly made to ‘la grant durté des Gyeus’,[2] a topos of the adversus Judaeos tradition associated with the hardness (duritia) of their hearts, which Christ referred to in Matthew xix.8,[3] the three knights of Arthur’s court who are proved worthy of attaining an open vision of the Grail, Pe

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Prebay, Z., D. Ebbott, M. Li, and P. Chung. "(482) Patients Receiving Urologic Implants Taking Sodium-Glucose Co-Transporter 2 Inhibitors, a Global, Propensity-Score Matched Analysis." Journal of Sexual Medicine 20, Supplement_1 (2023). http://dx.doi.org/10.1093/jsxmed/qdad060.454.

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Abstract Introduction Sodium-glucose co-transporter 2 inhibitors (SGLT2i) prevent the reabsorption of glucose and facilitate its excretion in urine. These medications are a newer treatment for Type 2 Diabetes Mellitus patients and have also been associated with positive cardiorenal effects. Patients taking these medications are at a hypothetical increased risk of urinary tract infections given the mechanism of action. Objective We questioned whether patients taking SGLT2i would be at an increased risk of genitourinary device infection or failure. As these medications are newer and without wide

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Kaplan, Louis. "“War is Over! If You Want It”." M/C Journal 6, no. 1 (2003). http://dx.doi.org/10.5204/mcj.2140.

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According to media conglomerate CNN, John Lennon and Yoko Ono’s peace crusade began in 1971. CNN’s on-line news group Showbiz on June 22, 1997 frames John and Yoko’s campaign for peace: “Former Beatle John Lennon was honoured posthumously Friday for his contributions to world peace at a star-studded ceremony in London for the 22nd Silver Clef awards. Lennon’s song “Imagine” has been a leading anthem for the peace movement”. This is a rather limited selection that overlooks a number of earlier (and more radical) possibilities in the Lennon-Ono musical arsenal. A 1969 article in Newsweek entitle

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Downes, Daniel M. "The Medium Vanishes?" M/C Journal 3, no. 1 (2000). http://dx.doi.org/10.5204/mcj.1829.

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Introduction The recent AOL/Time-Warner merger invites us to re-think the relationships amongst content producers, distributors, and audiences. Worth an estimated $300 billion (US), the largest Internet transaction of all time, the deal is 45 times larger than the AOL/Netscape merger of November 1998 (Ledbetter). Additionally, the Time Warner/EMI merger, which followed hard on the heels of the AOL/Time-Warner deal and is itself worth $28 billion (US), created the largest content rights organisation in the music industry. The joining of the Internet giant (AOL) with what was already the world's

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Gehrmann, Richard. "War, Snipers, and Rage from Enemy at the Gates to American Sniper." M/C Journal 22, no. 1 (2019). http://dx.doi.org/10.5204/mcj.1506.

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The concept of war is inextricably linked to violence, and military action almost always resounds with the emotion and language of rage. Since the War on Terror began in September 2001, post-9/11 expressions of terror and rage have influenced academics to evaluate rage and its meanings (Gildersleeve and Gehrmann). Of course, it has directly influenced the lives of those affected by global conflicts in war-torn regions of the Middle East and North Africa. The populace there has reacted violently to military invasions with a deep sense of rage, while in the affluent West, rage has also infiltrat

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Bruns, Axel. "What's the Story." M/C Journal 2, no. 5 (1999). http://dx.doi.org/10.5204/mcj.1774.

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Practically any good story follows certain narrative conventions in order to hold its readers' attention and leave them with a feeling of satisfaction -- this goes for fictional tales as well as for many news reports (we do tend to call them 'news stories', after all), for idle gossip as well as for academic papers. In the Western tradition of storytelling, it's customary to start with the exposition, build up to major events, and end with some form of narrative closure. Indeed, audience members will feel disturbed if there is no sense of closure at the end -- their desire for closure is a pow

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Burns, Alex. "Doubting the Global War on Terror." M/C Journal 14, no. 1 (2011). http://dx.doi.org/10.5204/mcj.338.

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Photograph by Gonzalo Echeverria (2010)Declaring War Soon after Al Qaeda’s terrorist attacks on 11 September 2001, the Bush Administration described its new grand strategy: the “Global War on Terror”. This underpinned the subsequent counter-insurgency in Afghanistan and the United States invasion of Iraq in March 2003. Media pundits quickly applied the Global War on Terror label to the Madrid, Bali and London bombings, to convey how Al Qaeda’s terrorism had gone transnational. Meanwhile, international relations scholars debated the extent to which September 11 had changed the international sys

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Seale, Kirsten. "Doubling." M/C Journal 8, no. 3 (2005). http://dx.doi.org/10.5204/mcj.2372.

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   ‘Artists are replicants who have found the secret of their obsolescence.’ (Brian Massumi)   The critical reception to British writer Iain Sinclair’s most recent novel Dining on Stones (or, the Middle Ground) frequently focused on the British writer’s predilection for intertextual quotation and allusion, and more specifically, on his proclivity for integrating material from his own backlist. A survey of Dining on Stones reveals the following textual duplication: an entire short story, “View from My Window”, which was published in 2003; excerpts from a 2002

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Sunderland, Sophie. "Trading the Happy Object: Coffee, Colonialism, and Friendly Feeling." M/C Journal 15, no. 2 (2012). http://dx.doi.org/10.5204/mcj.473.

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In the 1980s, an extremely successful Nescafé Gold Blend coffee advertising campaign dared to posit, albeit subliminally, that a love relationship was inextricably linked to coffee. Over several years, an on-again off-again love affair appeared to unfold onscreen; its ups and downs narrated over shared cups of coffee. Although the association between the relationship and Gold Blend was loose at best, no direct link was required (O’Donohoe 62). The campaign’s success was its reprisal of the cultural myth prevalent in the West that coffee and love, coffee and relationships, indeed coffee and int

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Gillett, James. "The Audience in Media Activism." M/C Journal 3, no. 1 (2000). http://dx.doi.org/10.5204/mcj.1830.

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Introduction Over the past thirty years media activism has expanded dramatically. Like never before, individuals and groups have access to personal computers, publishing software, fax, telecommunications, the Internet, community radio and television that enable them to participate in forms of cultural production previously reserved for an intellectual and political élite. Independently produced media among those who feel excluded from, even oppressed by, the dominant social order provides a means of raising awareness among oppressed or marginalised communities while at the same time challengin

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Molnar, Tamas. "Spectre of the Past, Vision of the Future – Ritual, Reflexivity and the Hope for Renewal in Yann Arthus-Bertrand’s Climate Change Communication Film "Home"." M/C Journal 15, no. 3 (2012). http://dx.doi.org/10.5204/mcj.496.

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About half way through Yann Arthus-Bertrand’s film Home (2009) the narrator describes the fall of the Rapa Nui, the indigenous people of the Easter Islands. The narrator posits that the Rapa Nui culture collapsed due to extensive environmental degradation brought about by large-scale deforestation. The Rapa Nui cut down their massive native forests to clear spaces for agriculture, to heat their dwellings, to build canoes and, most importantly, to move their enormous rock sculptures—the Moai. The disappearance of their forests led to island-wide soil erosion and the gradual disappearance of ara

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Rodan, Debbie. "Casualising the Use of Nonhuman Animals’ Bodies in ‘Meat Porn’ Television Programs and Websites." M/C Journal 27, no. 4 (2024). http://dx.doi.org/10.5204/mcj.3082.

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Introduction Rarely in cooking programs and Internet sites advertising cooked meat are nonhuman animals named as a member of a species or named individually – often they become “absent referents” (C.J. Adams 53). This occurs because the butchered animal becomes meat, and once this happens nonhuman animals are turned into an absent referent (C.J. Adams 51). In the rituals of the BBQ cooking programs and Internet sites nonhuman animals’ body parts are made invisible and commodified for the thrill of the perfect ‘grill’. Such language and visual aesthetics are used to intensify a viewer’s “arousa

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Bruns, Axel. "The Knowledge Adventure." M/C Journal 3, no. 5 (2000). http://dx.doi.org/10.5204/mcj.1873.

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In his recent re-evaluation of McLuhanite theories for the information age, Digital McLuhan, Paul Levinson makes what at first glance appears to be a curious statement: he says that on the Web "the common denominator ... is the written word, as it is and has been with all things having to do with computers -- and will likely continue to be until such time, if ever, that the spoken word replaces the written as the vehicle of computer commands" (38). This, however, seems to directly contradict what any Web user has been able to experience for several years now: Web content has increasingly come

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Maybury, Terrence. "The Literacy Control Complex." M/C Journal 7, no. 2 (2004). http://dx.doi.org/10.5204/mcj.2337.

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Usually, a literature search is a benign phase of the research regime. It was, however, during this phase on my current project where a semi-conscious pique I’d been feeling developed into an obvious rancour. Because I’ve been involved in both electronic production and consumption, and the pedagogy surrounding it, I was interested in how the literate domain was coping with the transformations coming out of the new media communications r/evolution. This concern became clearer with the reading and re-reading of Kathleen Tyner’s book, Literacy in a Digital World: Teaching and Learning in the Age

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