Relevant bibliographies by topics / Poisons

Academic literature on the topic 'Poisons'

Author: Grafiati
Published: 4 June 2021
Last updated: 3 March 2023

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Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Journal articles on the topic "Poisons":

1

B*, Swathy Krishnan, Prakhar Duggal, and Ravinder Kumar Tomar. "Variation in Poison’s Ratio with Change in Grade of Concrete and Type of Steel Reinforcement." International Journal of Recent Technology and Engineering 10, no. 1 (May 30, 2021): 168–72. http://dx.doi.org/10.35940/ijrte.a5825.0510121.

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The structure that are widely used around the gold now days are mainly composite structure. These types of models or structures are used to make long span lower story heights and also to give extra stiffness. The past result shows that most of the collapses of buildings occur when the structure is struck with earthquake or seismic load. The poison’s ratio is one of the most integral part which gives stability for the structure. In this research it is about the change is the poison’s ratio that occurs with the change in percentage of steel and the grade of concrete in a reinforced concrete section. The variation in poisons ratio shows the variation in the stability of the structure. The study of the poisons ratio will help in a better practical design of the structure to prevent or the resist the structure from collapse during earthquake. In this paper we will see the experimental variation of the poisons ratio of column and we will analysis the behavior using software. Poison’s ratio usually deals with the lateral strain and linear strain. This poisons ratio was found out by Simeon poison. It is one of the most important aspects in the design of any kind of structure.
2

Kumari, Meena, Pattu Swarna Latha, and Kalyanasundaram . "Epidemiological and clinical profile of various plant poisons in a tertiary care center in South Tamilnadu, India." International Journal of Research in Medical Sciences 7, no. 9 (August 27, 2019): 3517. http://dx.doi.org/10.18203/2320-6012.ijrms20193939.

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Background: Plant poisoning is a common scenario in a toxicology unit . Some of the plants contain active components used as medicines. However, some of the plant constituents are poisonous with wide variety of clinical manifestations. Authors aimed to study the pattern of various types of plant poisons and clinical presentations and complications of various plant poisons admitted in our toxicological unit.Methods: A total of 87 patients admitted with history of plant poison ingestion, in toxicological unit of Tirunelveli medical college were studied . It was a retrospective observational study and was done over a period of one year.Results: Out of 87 cases studied, 92%were due to consumption with suicidal intention. Plant poisoning ranks second only to pesticide poisoning . among the plant poisons encountered 66.6% were due to Oleander poison, followed by Datura (8%) and Glory lily(5.7%). Common parts of plant consumed by patients include seeds and plant oils . Vomiting and abdominal pain were the commonest presentations. Encephalopathy, dyselectrolytemia and arrhythmias were the notable complications in our study.Conclusions: Early admission and prompt first aid and monitoring at tertiary care center are key to the reduced mortality. The study throws light on various manifestations, toxic parts and complications of plant poisons.
3

Kumar, Sunil, and Swatika Swatika. "CONCEPT OF ANTIDOTES V/S PRATIVISHA IN AYURVEDA - A REVIEW ARTICLE." International Ayurvedic Medical Journal 9, no. 10 (October 15, 2021): 2554–58. http://dx.doi.org/10.46607/iamj4309102021.

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Ayurveda is a traditional system of medicine with historical roots in the Indian subcontinent. It is one of the most technical medical systems in the world with an extended record of scientific experience. Ayurveda tells the way of life and how to live healthily and stay happy. It has eight prime branches of medicine. Agada tantra is one of the specialized divisions of Ayurveda that offer scrupulously thorough information about animate and non-animated poisons and methods of removal of these poisons from the body. It chiefly advocates different antidotes for equip- ment that are poisonous to the human body. There are various ancient books which have relation regarding the Toxicology Agada tantra in which we can get references regarding the above mentioned and treated as such with Antidotes. Antidotes are the substances used to counteract or deactivate the effects of poison. Poison may be by plant, or through animal bites like snake bites etc., agricultural poisons, poisonous metals and minerals etc. There are mainly two types of poison mentioned in Ayurveda, are Sthavar visha and Jangham visha., Common antidote in Ayurveda is Swarna, Ghrita, Godudha and Madhu etc. antidote plays important role in the treatment of poisoning which we can see in the current paper, the main moto of doctor is to save the patient's life. In Ayurveda, our Achar- yas mentioned the different types of poisonous substances and their antidote under Visha Chikitsa references. The concept of Prativisha which is existed since ancient time needs to be supplemented, explained, refurbish and narrate for proper treatment. So, this article aims to collect the references of curative and preventive measures of poisoning. Keywords: Visha, Antidotes, Vagbhatta, Vishavaidyajyotsnika
4

Cole, Leonard A. "The Poison Weapons Taboo: Biology, Culture, and Policy." Politics and the Life Sciences 17, no. 2 (September 1998): 119–32. http://dx.doi.org/10.1017/s0730938400012119.

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Although the threat of chemical and biological warfare has grown, the actual use of poisons as weapons of war or terrorism remains rare. The reason rests in part on a long-standing taboo about poison weapons. This article explores possible biological and cultural explanations for the taboo; surveys the use of poisons by other species, by tribal groups, and by ancient societies; and considers the importance of snakes in developing attitudes about poisons. Reluctance to use poison weapons may have had its origin in the linkage of medicine, poisons, and mysticism common in societies everywhere. Whatever the reasons, however, antipathy to poison weapons is deep-seated, and most nations have embraced the norm that deems these weapons morally repugnant. Policies should be sought that enhance this attitude and therefore make the use of such weapons less likely.
5

Rosso, Ana María. "Antidotes and Counter-Poisons in the Ancient World: Onions (hdw) (Allium cepa L.) in Egypt, the Preferred Antitoxic for Snake Bites." Journal of the American Research Center in Egypt 55 (November 22, 2019): 173–87. http://dx.doi.org/10.5913/jarce.55.2019.a011.

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Modern toxicology focuses on studying adverse effects of poisons and chemical exposures but understanding the toxicity and risks developing antidotes and counter-poisons has taken science a long time. The lack of a proper theory in antiquity to treat poisoned patients didn’t allow for the improvement in diagnosis and treatment. However, in Papyrus Brooklyn 47.2180 dated to the fourth century bc, ancient Egyptians classified local snakes, poisonous symptoms, diagnosis, and simple treatments with drugs and magical incantations, ignoring the effectiveness of remedies and their potential side effects. To solve the problem and protect themselves, people first tried to observe animal behavior and the reactions to different substances ingested. Ancient medicine found certain alexipharmic therapy or antidotes to reverse lethal intoxication based on two axioms: similia similibus, studying the tolerance of a poison and the dose, as with the modern theory of immunity, and contraria contraris, using substances with contrary properties, as in the case of antibiotics. This allowed the development of pharmacology, because “For the Egyptians, poisons are substances that may be offset by antidotes or substances with opposite properties.” An extremely common food, the Egyptian species of onion Allium cepa L., seemed to be the preferred alexipharmic to repel snake venom. Its characteristic smell comes from a volatile and fragrant sulphide gas and, through recent chemical research, scientists have reported its antibiotic properties, since it contains allium, transformed in allicin, the key ingredient responsible for its broad-spectrum and anti-bacterial activity. Useful for all kinds of treatment in the Egyptian pharmacopoeia, its defensive power also became known abroad.
6

Hussain, Gazala, and Vinay R. Kadibagil. "Gruhadhuma in Agada Yogas: a review." Journal of Drug Delivery and Therapeutics 8, no. 6-s (December 15, 2018): 370–72. http://dx.doi.org/10.22270/jddt.v8i6-s.2106.

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Gruhadhuma is an ingredient mentioned in Ayurveda pharmaceutics in a group of drugs termed as panchamrittika. It is an ingredient that is used in various formulations in the treatment of vishas (poisons). Many formulations for the management of various poisons like snake bite, keetavisha (insect poisons), etc. have been explained in Ayurveda treatise that contains it as an ingredient. The agada yogas (formulations for poisonous bites) mentioned for the management of various poisons in bruhatrayee contain ingredients that are both herbal and mineral in origin. Formulations having gruhadhuma have been mentioned for oral administration, as nasya (nasal inhalation), anjana (collyrium), lepa (anointment), etc. A literary search through the treatises of Ayurveda has put a light on the various formulations containing it. Keywords: Agadayogas, Gruhadhuma, poisons, formulations
7

Puu, Yustina Maria Silvia Wonga, and Adrianus A. Janggo. "UJI EFEKTIVITAS BEBERAPA JENIS TANAMAN SEBAGAI PESTISIDA NABATI TERHADAP HAMA GUDANG Callosobrunchus sp." AGRICA 6, no. 1 (July 22, 2020): 33–42. http://dx.doi.org/10.37478/agr.v6i1.424.

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This research aimed to determine the effectiveness of pesticide plant leaves to the growth of warehouse pest (Callosobrunchus sp)and plant extracts that causes the highest mortality of warehouse pests (CallosobrunchusSp). The design used in this study was a Complete Randomized Block Design (CRBD) with the treatments used are PN0 (aquades), PN1 (Leeksextract), PN2 (extracts of Tagetes), PN3 (leaves Lemongrass Extract). Variable observations in this study are the toxins, contact poisons, nerve poison, repellent and antioviposit. The results showed that the extract of leaves of Tagetes, Lemongrass and Scallion effect on the growth of pest warehouse (Callosobrunchus sp) on observations of Toxins, contact poisons, a nerve poison, repellent and antioviposit. Leaves Tagetes extract is the right plant and effective towards mortality of warehouse pest (Callosobruschus Sp) at 80.89% of poisons contact, the nerve at 84,02%, and 85,05% of repellent activity, antioviposit at 97,6%.
8

Chatterjee, Arup K. "Aconite in Victorian Tropical Toxicology." Canadian Journal of Health History 39, no. 2 (September 1, 2022): 281–310. http://dx.doi.org/10.3138/cjhh.2022-554-122021.

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Beginning as a symptomatic reading of Arthur Conan Doyle’s use of a fictional African root poison, the Radix pedis diaboli, in “The Adventure of the Devil’s Foot” (1907), and Indian poisoned darts in The Sign of the Four (1890), this article makes some general comments on the history of colonial tropical toxicology, focusing on the Indian aconite ( Aconitum ferox) and its roots ( Radix aconiti indica). Arguably, Doyle had aconite in his mind while creating the fictional African root poison. Victorian toxicologists, who were deeply interested in Indian poisons, created stereotypes of India as congeries of melancholy and culturally backward, industrially primitive, and morally corrupt societies. Doyle’s fictional poisons were influenced by a normative cultural bias that saw tropical pharmakons like aconite with an Orientalizing gaze. By shifting the geographical focus from Doyle’s “Ubangi country” to nineteenth-century India, I draw attention to a larger spectrum of tropical toxicology. The colonial zeal to taxonomize the properties and utility of tropical pharmakons obsessively revolved around their toxic uses as criminal weapons or accidental killers, while marginalizing the medicinal uses that the plant had been historically put to by ancient Indian physicians.
9

Bansal, Alka, Smita Jain, Ashish Agrawal, Monica Jain, Shivankan Kakkar, and Sneha Arora. "Probabilistic model to predict the outcome in acute suicidal chemical poisoning cases from age and gender of patient and type of chemical poison consumed." Scripta Medica 52, no. 2 (2021): 104–8. http://dx.doi.org/10.5937/scriptamed52-32096.

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Background: Acute chemical poisoning is a significant global health problem. Chemical poisons include agrochemical, household and industrial poison subtypes. The present study used a probabilistic model based on age, gender and type of poison consumed by the patient to predict the outcome in acute suicidal poisoning cases. Material and methods: A prospective observational study was conducted at emergency department of SMS Hospital, Jaipur, India, from January 2019 to February 2020. Patients over 15 years of age with poisoning severity score 2 or above were included in the study. Probabilistic model was used to predict the outcome measured in terms of cure, death and left against medical advice (LAMA) using Minitab 14. Results: Poisoning cases were 0.32 % of all emergency presentations. Out of them, 857 (59.6 %) had consumed chemical poison. Their mean age was 32 years and men to women ratio was 1.22. Agrochemical subtype was most common followed by household and industrial poisoning. Analysis by Probabilistic model showed that person between 30-60 years is more likely to be cured and chances of death and LAMA are highest in age group 60-75. Gender-wise, men have higher possibility for recovery. Besides, a person has highest chances of recovery in case of household poisons; death is most common in industrial poisons and LAMA in agrochemical poisons. Conclusion: The study concluded that in poisoning, patients' basic information like age, gender, type of poison consumed can be used to identify high death probability and LAMA risk patients. It will assist in designing and monitoring the most effective strategies for them.
10

Jaglan, Nisha. "A Review on Conceptual Study Of Concocted Poison: Garavisha." International Research Journal of Ayurveda & Yoga 05, no. 10 (2022): 92–96. http://dx.doi.org/10.47223/irjay.2022.51015.

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Poison causes concern to all living beings by making organism grievously ill, its functioning and leading to death in certain cases. One of the hidden poisons is the concocted poison known as Gara visha. In ayurveda the Gara visha is considered as one of the forms of Kritrimvisha which gets formed by combination of two or more than two poisonous or non-poisonous drugs and affects the whole body by vitiating all the dhatus in the body. We unknowingly consume various combination substances which are harmful to our health. The insect powder, human waste product or some of the agents of Gara visha. This study aims to establish that Gara Visha has significant role in causing toxic symptoms due to its various uses in present society and Ayurveda offers its effective management.
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Journal articles Dissertations / Theses Books

Dissertations / Theses on the topic "Poisons":

1

Ireland, Benjamin. "Amines in Olefin Metathesis: Ligands and Poisons." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34342.

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Olefin metathesis is a powerful tool for assembly of carbon-carbon bonds. Amines and related N-donors are problematic functional groups in Ru-catalyzed olefin metathesis - a well- documented, but poorly understood problem. The first part of this thesis focuses on amine-induced deactivation pathways; two of which are described in depth. Alkylidene abstraction, a previously unknown reaction for nitrogen nucleophiles, was observed for smaller and less Bronsted-basic amines. Deprotonation of the metallacyclobutane intermediate formed during catalysis is prominent for highly Bronsted basic or sterically bulky N-donors. Monosubstituted (and, by extension unsubstituted) metallacyclobutanes are particularly vulnerable to deprotonation. For each pathway, the fate of the alkylidene Ru=CHR functional group proved key in determining the nature of deactivation. Both pathways have been detected during catalysis, as evidenced by formation of diagnostic amine (RCH2NR2’) or substituted propene products. A combination of quantitative NMR and GC-MS analysis was used to identify these species on loss of the Ru-alkylidene functional group. The second part of this thesis focuses on incorporating amines into catalyst design – an under-utilized strategy in the context of Ru-catalyzed olefin metathesis. A modified Grubbs-type catalyst was developed featuring a bulky, relatively non-basic biaryldiamine ligand. Metathesis activity for this catalyst was comparable, and in some cases superior to the most widely-used homogeneous catalysts currently available. Several new, related Ru-benzylidenes were also prepared and fully characterized in conjunction with the mechanistic studies described above. Progress toward development of N-anion-containing metathesis catalysts is also discussed. Synthesis of Ru-hydride complexes originally intended for this purpose allowed for a fundamental study of the coordination chemistry and reductive elimination chemistry of the NPh2– anion.
2

Taylor, Erin N. Bickford Susan. "Specious poisons? reputation, gender, and democratic politics /." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,426.

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Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2006.
Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Political Science." Discipline: Political Science; Department/School: Political Science.
3

Liu, Yan. "Toxic Cures: Poisons and Medicines in Medieval China." Thesis, Harvard University, 2015. http://nrs.harvard.edu/urn-3:HUL.InstRepos:17467528.

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This dissertation explores the medicinal use of poisons in China from the third to the tenth century, which is when the major outlines of Chinese toxicological thought took shape. Challenging a widespread view that contrasts the benign naturalness of Chinese herbal remedies with the dangerous side effects of Western synthetic drugs, my research highlights the centrality of poisons to the practice and theory of medicine in China. Chinese doctors regularly relied on a large number of substances that they recognized as toxic to combat sickness, and identified toxicity as the central pillar for the classification of drugs. I argue that the boundary between poisons and medicines was always hazy in medieval China; it was not the substance itself, but how it was used and experienced that mattered. To examine this crucial yet ignored feature of Chinese medicine, my dissertation develops the following themes. The first is that drugs in medieval China were not fixed entities with unique effects. The effect of a given substance—whether it healed as a medicine, or sickened or killed as a poison, or altered a person in myriad other ways—varied both with usage and with processing. Subsequently, Chinese doctors developed a variety of techniques (the dosage, the drug combination, and the drug preparation) to mitigate the toxicity of a poison while preserving its therapeutic potency. Secondly, I highlight the intimate relation between bodily experience and the understanding of poisons. By studying the alchemical practice of ingesting toxic minerals, I show that the violent bodily effects induced by these substances were often perceived as confirmations of efficacy rather than worrying signs of pathology. My third theme is the circulation of toxicological knowledge across geographical and social domains. I argue that standardized textual knowledge propagated by the state was fluidly transformed in practice, contingent upon the availability of pharmacological ingredients and the needs of local people. Finally, I turn to non-poisons, especially foods, in Chinese pharmacy, and identify a distinctive character of Chinese medicine—the ingestion of mild substances to nourish the body and prolong life. Chinese medicine thus developed through the interaction of two related, but distinct enterprises—the fight against sickness, and the quest for ever-enhanced vitality.
History of Science
4

Malangu, Ntambwe. "Acute poisoning in three African countries: Botswana, South Africa and Uganda." Thesis, University of Limpopo (Medunsa Campus), 2011. http://hdl.handle.net/10386/674.

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Thesis (PhD (Epidemiology)-- University of Limpopo, 2011.
Acute poisoning constitutes one of the main reasons why patients visit emergency departments of hospitals. However, the burden and pattern of acute poisoning in African countries are not well established, hence the need for this study. This study was conducted in order to compare the patterns of acute poisoning in three countries, namely, Botswana, South Africa, and Uganda. Specifically, this study examined the similarities and differences in the patterns of occurrence of acute poisoning based on the sociodemographic characteristics of the victims, the toxic agents involved, and the circumstances of the incidents. The study was based on six papers published on the topic. Papers I and II about Botswana covered a period of 24 months (January 2004 - December 2005) and six months (January - June 2005) respectively. The data from Uganda, as reported in Paper III, covered a six-month period (January-June 2005); while studies in South Africa, Papers IV to VI, covered respectively six (January-June 2005) and 18 months (January 2000-June 2001). A re-analysis of data from Papers II to IV was conducted after recoding age category and the grouping of toxic agents. In total, the six Papers reported data on 1780 patients; 54.8% of them were male. The median age was 24 years in Uganda, but as low as 17 years in Botswana and South Africa. In Botswana and South Africa, acute poisoning incidents occurred mostly in children younger than 12 years old, then decreased among teenagers, and increased again among young adults, before decreasing among patients over 30 years old. On the contrary, in Uganda there was that less than 5% of children younger than 12 years who were victims of poisoning. There was an increase in the prevalence of acute poisoning among teenagers and young adults before a decrease occurred among adults over 30 years old. The overall case fatality rate was 2.1 %, ranging from 1.4% in Uganda, 2.4% in South Africa, to 2.6% in Botswana. With regard to similarities across the three countries, it was found that among teenagers, girls committed more deliberate self-poisoning than boys; while in young adults, men committed more self-poisoning than women. With regard to toxic agents, household products were involved in fatal Page 9 of 136 outcomes in all three countries; while agrichemicals were more involved in deliberate than accidental poisonings; food poisoning affected more females than males. With regard to disparities across the three countries, the age and gender of the victims, the circumstances of the incidents and the types of toxic agents played a significant role. With regard to gender, the majority of the victims were males in Uganda, females in South Africa; while in Botswana, females and males were affected equally. Among teenagers, the toxic agents most involved in the poisoning incidents were pharmaceuticals in Botswana; household chemicals in South Africa; but agrichemicals in Uganda. While the majority of incidents happened by accident in Botswana and South Africa, being respectively 76.7% and 59.1%; in Uganda, 64.5% of acute poisoning cases were deliberate self¬poisoning. Deliberate self-poisoning was responsible for 50% of deaths in Uganda, 30% in South Africa, but no death in Botswana. The majority of deaths occurred among teenagers in South Africa; in Uganda it was among adults over 30years; while in Botswana, the majority of deaths were distributed almost equally amongst children younger than 12years old and young adults. Diverse products were involved in fatal outcomes. In South Africa, pharmaceuticals, particularly drugs of abuse, cocaine and marijuana; as well as carbon monoxide, and organophosphates were involved in fatalities. While, in Botswana, the products involved were paraffin, traditional medicines, pharmaceuticals, food poisoning, plants, and snake envenomation. In contrast, in Uganda, alcohol intoxication, organophosphates, carbon monoxide, and some unspecified household products lead to fatalities. Household chemicals were involved in the deaths of victims in all three countries; but the extent of their involvement differed from country to country. This group of products was responsible of 75% of deaths in Uganda, half of deaths in South Africa, and in a third of deaths in Botswana. Agrichemicals were involved in the deaths of victims in Uganda and South Africa, but not in Botswana. They were involved in a quarter of deaths in Uganda and 10% of deaths in South Africa. Page 10 of 136 Plants and traditional medicines were involved in two-thirds of the deaths only in Botswana; while pharmaceuticals were involved in 40% of fatal outcomes only in South Africa. In conclusion, the contextual factors of each country led to a pattern of acute poisoning that showed some similarities with regard to the distribution of deliberate self-poisoning among females, teenagers, and young adult victims. However, there were disparities relating to the differential access to toxic agents, based on the age and gender of the victims. Moreover, though the case fatality rate was similar across the three countries, the distribution of deaths based on age, gender, circumstances of poisoning and types of toxic agents involved differed among the three countries. These findings suggest that multifaceted interventions should be implemented including policy development, enforcement of the existing legislation, and the establishment of a surveillance mechanism, in-service training of clinicians and revision of treatment guidelines. These interventions should be tailored to meet the specific realities of each country.
5

Fox, Mary Elizabeth. "Mechanisms of action of anticancer DNA topoisomerase II poisons." Thesis, University of Cambridge, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239716.

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Kerry, Mark Anthony. "The design and synthesis of novel topoisomerase I poisons." Thesis, University of Sunderland, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.245780.

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7

Lancaster, Cynthia Sue. "CDC45 function alters cell sensitivity to DNA topoisomerase I poisons." View the abstract Download the full-text PDF version, 2008. http://etd.utmem.edu/ABSTRACTS/2008-007-Lancaster-index.html.

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Thesis (Ph.D)--University of Tennessee Health Science Center, 2008.
Title from title page screen (viewed on July 16, 2007). Research advisor: Mary-Ann Bjornsti, Ph.D. Document formatted into pages (xii, 123 p. : ill.). Vita. Abstract. Includes bibliographical references (p. 118-123).
8

Hobbs, Jeanette Roseanna. "Structural studies on the DNA binding modes of topoisomerase poisons." Thesis, University of Reading, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342117.

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9

Balosso, Jacques. "Mecanismes radiobiologiques des associations concomitantes radiotherapie-poisons de topoisomerase ii." Paris 7, 1997. http://www.theses.fr/1997PA077168.

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Les associations radiotherapie-chimiotherapie concomitante (arcc), constituent l'une des principales modalites de traitements anti-cancereux. Un tres grand nombre d'arcc sont possibles vu la variete des drogues et des schemas d'irradiation disponibles. Aussi, des informations fondamentales sur les interactions de ces therapeutiques aux niveaux cellulaire et tissulaire sont-elles indispensables pour fournir des rationnels aux cliniciens. Ce theme a ete aborde avec deux poisons de topoisomerase ii, la pazelliptine (pze) et l'etoposide (eto), grace a une approche cellulaire. Des cultures cellulaires humaines et murines de 5 lignees differentes ont ete utilisees en croissance ou en inhibition de contact. Les irradiations (rx), de 0 a 10 gy, ont ete faites par des photons gamma ou x. L'elution de l'adn sur filtre permit la quantification des coupures simples ou double brin, le clonage in-vitro la mesure des survies cellulaires, la cytometrie de flux l'etude de la distribution dans le cycle cellulaire, et la representation isobolographique normalisee l'evaluation de la synergie des arcc. L'arcc pze-rx sur les cellules en croissance peut produire un effet supra-additif. Il n'y a pas de modification pharmacocinetique, mais une augmentation du taux des lesions residuelles et une forte cooperation cytocinetique par les redistributions dans le cycle cellulaire. Avec eto-rx sur les cellules en croissance la supra-additivite evolue en fonction du temps selon une courbe biphasique revelant 2 mecanismes de sensibilisation. Le premier est une hypersensibilite durant la phase de reparation des radio-lesions sub-letales, le second une hypersensibilite de la phase g2 post-rx. La pze et le vp16 n'ont aucun effet sur les cellules quiescentes sauf aux tres fortes doses avec la pze. Il n'y a pas d'effet sur la reparation des lesions potentiellement letales. Les sequences ou les deux traitements sont les plus proches dans l'ordre rx drogue produisent les interactions les plus synergiques. C'est resultats sont discutes dans la perspective d'une application clinique. Une conception unifiee des concepts du laboratoire et de la clinique est proposee, basee en particulier sur la terminologie des isobologrammes et sur l'etude des effets tardifs des arcc en clinique.
10

TADDEI, PATRICK. "Pharmacodependance a l'amineptine : bilan du centre anti-poisons de marseille." Aix-Marseille 2, 1993. http://www.theses.fr/1993AIX20086.

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Books on the topic "Poisons":

1

Hyams, Jay. Poisons. Springhouse, Pa: Springhouse Corp., 1986.

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2

Britain, Great. Poisons: The Poisons (Amendment) Rules 1989. London: HMSO, 1989.

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Instruments, Great Britain Statutory. Poisons: The Poisons (Amendment) Rules 1986. London: H.M.S.O, 1986.

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Instruments, Great Britain Statutory. Poisons: The poisons list order, 1986. London: H.M.S.O, 1986.

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Vallée, Arthur. Le poison dans l'histoire et les grandes empoisonneuses. [Québec?: s.n.], 1996.

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Britain, Great. Poisons: Poisons (Amendment) Regulations (Northern Ireland) 1987. [Belfast]: HMSO, 1987.

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Britain, Great. Poisons: Poisons (Amendment) Regulations (Northern Ireland) 1990. [Belfast]: HMSO, 1990.

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Britain, Great. Poisons: Poisons (Amendment) Regulations (Northern Ireland) 1994. Belfast: HMSO, 1994.

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Kolok, Alan S. Modern Poisons. Washington, DC: Island Press/Center for Resource Economics, 2016. http://dx.doi.org/10.5822/978-1-61091-609-7.

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Instruments, Great Britain Statutory. Poisons: The poisons (amendment no. 2) rules, 1986. London: HMSO, 1986.

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Book chapters on the topic "Poisons":

1

George, David J. "Carbon Monoxide." In Poisons, 75–82. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-10.

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George, David J. "Cyanide." In Poisons, 83–88. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-11.

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George, David J. "Ethylene Glycol." In Poisons, 89–96. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-12.

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George, David J. "Nicotine." In Poisons, 97–103. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-13.

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George, David J. "Strychnine." In Poisons, 105–9. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-14.

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George, David J. "Thallium." In Poisons, 111–17. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-15.

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George, David J. "Aspirin." In Poisons, 119–24. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-16.

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George, David J. "Acetaminophen." In Poisons, 125–29. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-17.

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George, David J. "Alcohol." In Poisons, 131–41. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-18.

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George, David J. "Opioids." In Poisons, 143–53. Boca Raton : CRC Press, [2018]: CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-19.

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Conference papers on the topic "Poisons":

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Yasui, Sritana C. "FTIR analysis of food poisons." In Luebeck - DL tentative, edited by Herbert M. Heise, Ernst H. Korte, and Heinz W. Siesler. SPIE, 1992. http://dx.doi.org/10.1117/12.56500.

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SanBing, Wang, Xie Qilin, and He ChaoHui. "Application of the Burnable Poison in the Design of Space Nuclear Reactor." In 2017 25th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/icone25-66393.

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Abstract:
The previous research showed that the application of burnable poison was helpful to improve the criticality safety of space nuclear reactor (SNR). In order to analyze the worth of burnable poison in the SNR’s design, a model of homogeneous reactor had firstly been built based on the design of SAFE400. Comparing its difference with the real design of SAFE400 through criticality calculation, the precise of our model had been verified. Then the influence of the criticality parameters and immersion accident character parameters for this model had been analyzed for the application of the different burnable poisons (such as samarium, europium or gadolinium). The calculation results had shown that the application of the most of the burnable poisons would soften the neutron spectrum and induced a decrement of reactor’s keff in the beginning of life. However, the immersion accident analysis gave out another result that only the reactor using gadolinium could ensure the criticality safety of reactor after it made its initial keff equal with the design value. Meanwhile, compared with the initial design of SAFE400, in one hand, the burn-up results had shown that the decrement of homogeneous reactor’s reactivity using gadolinium as burnable poison was deceased after the 10 years full power operation; in other hand, its neutron spectrum became more softer with the operation time; and what’s more important, the amount of the burnable poison was not decreased with burn-up during its service life-time. These results implied that the application of the burnable poison (especially for gadolinium) could highly ensure the criticality safety and stable operation of SNR.
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Hu, Xinyang. "German Navy: A Choice from Two Poisons." In 2022 3rd International Conference on Mental Health, Education and Human Development (MHEHD 2022). Paris, France: Atlantis Press, 2022. http://dx.doi.org/10.2991/assehr.k.220704.154.

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Sandoval-Segura, Pedro, Vasu Singla, Liam Fowl, Jonas Geiping, Micah Goldblum, David Jacobs, and Tom Goldstein. "Poisons that are learned faster are more effective." In 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW). IEEE, 2022. http://dx.doi.org/10.1109/cvprw56347.2022.00033.

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Awan, Muhammad Qasim, Liangzhi Cao, and Hongchun Wu. "Burnable Poisons Alternative Configurations in AT-FCM PWR Fuel Assembly." In 2017 25th International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/icone25-66444.

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The Fukushima Daiichi Nuclear Power Plant accident in Japan was one of the severest accidents in history of nuclear power plants. This accident changed the prospect of the Nuclear Engineers all around the globe, regarding safety enhancement of nuclear reactors. Since then many aspects of nuclear reactors regarding the improvements of safety features are under investigation and R&D efforts are underway around the world. Use of innovative fuels in present as well as future reactor designs is one of the major potential areas of these ongoing efforts. Fully Ceramic Micro-Encapsulated (FCM) fuel originally developed for use in high temperature gas cooled nuclear reactors, has proven worth for operating in high temperature environment with high burn-up. Due to its additional fission product barrier in the form of strong SiC layer, it is worth using for application as PWR fuel, thus providing potential benefits related to safety and operational aspects of power plant. However, use of FCM fuel in a PWR also has some operational constraints such as the moderator temperature coefficient (MTC) of reactivity has less negative value and even becomes positive when higher concentration of soluble boron is used for the reactivity control. Thus, use of burnable poison material becomes more important to control the access reactivity throughout the cycle length in such a way the quantity of soluble boron to be used is much lower to prevent the positive MTC value or even soluble boron free operation is possible. In present studies a new candidate designs of PWR fuel assembly of 12×12 square array configuration has been used to study the BP material impact on cycle length. Monte Carlo code MVP-BURN is utilized for the analysis to accurately model the double heterogeneity arising due to TRISO type fuel. Two standard materials i.e. Erbia and Gadolinia are used and different configuration including mixing of BP in matrix material, fuel kernel and in QUADRISO form are analyzed and compared with each other. Impact of the residual poison are also analyzed and additional enrichment required to overcome the impact of residual BP material reactivity are calculated. Different configurations support different BP materials. However, it has been found that with an appropriate combination of both materials and configuration, it is possible to minimize the use of soluble boron. Finally, the recommended assembly configuration is analyzed for MTC value during the entire cycle length, showing sustainability of negative values of MTC for the region of interest. With this kind of arrangements, it is possible to use FCM type fuel for present as well as future generations of the PWRs.
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Kadnichanskaya, E. F. "POISONS AND THEIR FORENSIC VALUE IN THE INVESTIGATION OF CRIMES." In XIV International Social Congress. Russian State Social University, 2015. http://dx.doi.org/10.15216/rgsu-xiv-191.

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Ball, Douglas J., Adil G. Mohammed, and William A. Schmidt. "Application of Accelerated Rapid Aging Test (RAT ) Schedules with Poisons: The Effects of Oil Derived Poisons, Thermal Degradation and Catalyst Volume on FTP Emissions." In International Fuels & Lubricants Meeting & Exposition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1997. http://dx.doi.org/10.4271/972846.

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Lafyatis, David S., Rick Petrow, and Chris Bennett. "The Effects of Oil-Derived Poisons on Three-Way Catalyst Performance." In SAE 2002 World Congress & Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2002. http://dx.doi.org/10.4271/2002-01-1093.

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Nadykto, B. A. "New nuclear safe plutonium ceramic compositions with neutron poisons for plutonium storage." In Plutonium futures-The science (Topical conference on Plutonium and actinides). AIP, 2000. http://dx.doi.org/10.1063/1.1292208.

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Beck, D. D., J. W. Sommers, C. L. DiMaggio, D. R. Monroe, and D. A. Frank. "Impact of Oil-Derived Catalyst Poisons on FTP Performance of LEV Catalyst Systems." In International Fuels & Lubricants Meeting & Exposition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1997. http://dx.doi.org/10.4271/972842.

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Reports on the topic "Poisons":

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Williamson, T. G., and A. Q. Goslen. Metal Poisons for Criticality in Waste Streams. Office of Scientific and Technical Information (OSTI), June 1996. http://dx.doi.org/10.2172/636037.

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Ciccone, V. J., M. B. Carmer, and J. I. Daniels. Evaluation of military field-water quality: Volume 3, Opportunity poisons. Office of Scientific and Technical Information (OSTI), December 1987. http://dx.doi.org/10.2172/6903360.

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Renier, J. A. Development of Improved Burnable Poisons for Commercial Nuclear Power Reactors. Office of Scientific and Technical Information (OSTI), April 2002. http://dx.doi.org/10.2172/814398.

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M. L. Grossbeck J-P.A. Renier Tim Bigelow. Development of Improved Burnable Poisons for Commercial Nuclear Power Reactors. Office of Scientific and Technical Information (OSTI), September 2003. http://dx.doi.org/10.2172/820689.

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Ciccone, V. J., M. B. Carmer, and Jeffrey I. Daniels. Evaluation of Military Field-Water Quality. Volume 3. Opportunity Poisons. Fort Belvoir, VA: Defense Technical Information Center, December 1987. http://dx.doi.org/10.21236/ada241521.

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Apiyo, Eric, Zita Ekeocha, Stephen Robert Byrn, and Kari L. Clase. Improving Pharmacovigilliance Quality Management System in the Pharmacy and Poisions Board of Kenya. Purdue University, December 2021. http://dx.doi.org/10.5703/1288284317444.

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Abstract:
The purpose of this study was to explore ways of improving the pharmacovigilance quality system employed by the Pharmacy and Poisons Board of Kenya. The Pharmacy and Poisons Board of Kenya employs a hybrid system of pharmacovigilance that utilizes an online system of reporting pharmacovigilance incidences and a physical system, where a yellow book is physically filled by the healthcare worker and sent to the Pharmacy and Poisons Board for onward processing. This system, even though it has been relatively effective compared to other systems employed in Africa, has one major flaw. It is a slow and delayed system that captures the data much later after the fact and the agency will always be behind the curve in controlling the adverse incidents and events. This means that the incidences might continue to arise or go out of control. This project attempts to develop a system that would be more proactive in the collection of pharmacovigilance data and more predictive of pharmacovigilance incidences. The pharmacovigilance system should have the capacity to detect and analyze subtle changes in reporting frequencies and in patterns of clinical symptoms and signs that are reported as suspected adverse drug reactions. The method involved carrying out a thorough literature review of the latest trends in pharmacovigilance employed by different regulatory agencies across the world, especially the more stringent regulatory authorities. A review of the system employed by the Pharmacy and Poisons Board of Kenya was also done. Pharmacovigilance data, both primary and secondary, were collected and reviewed. Media reports on adverse drug reactions and poor-quality medicines over the period were also collected and reviewed. An appropriate predictive pharmacovigilance tool was also researched and identified. It was found that the Pharmacy and Poisons Board had a robust system of collecting historical pharmacovigilance data both from the healthcare workers and the general public. However, a more responsive data collection and evaluation system is proposed that will help the agency achieve its pharmacovigilance objectives. On analysis of the data it was found that just above half of all the product complaints, about 55%, involved poor quality medicines; 15% poor performance, 13% presentation, 8% adverse drug reactions, 7% market authorization, 2% expired drugs and 1% adulteration complaints. A regulatory pharmacovigilance prioritization tool was identified, employing a risk impact analysis was proposed for regulatory action.
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Chandler, David, G. Ivan Maldonado, and Trent Primm. Reactivity Accountability Attributed to Reflector Poisons in the High Flux Isotope Reactor. Office of Scientific and Technical Information (OSTI), December 2009. http://dx.doi.org/10.2172/970898.

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Lyman, C. E. Analytical electron microscopy of catalyst promoters, poisons, and active species: Progress report, (July 1986--September 1988). Office of Scientific and Technical Information (OSTI), November 1988. http://dx.doi.org/10.2172/6255945.

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Goodsell, Alison Victoria, Martyn Thomas Swinhoe, Vladimir Henzl, Carlos D. Rael, and David J. Desimone. Differential Die-Away Instrument: Report on Benchmark Measurements and Comparison with Simulation for the Effects of Neutron Poisons. Office of Scientific and Technical Information (OSTI), March 2015. http://dx.doi.org/10.2172/1177167.

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Burton Davis, Gary Jacobs, Wenping Ma, Khalid Azzam, Janet ChakkamadathilMohandas, and Wilson Shafer. Sensitivity of Fischer-Tropsch Synthesis and Water-Gas Shift Catalystes to Poisons form High-Temperature High-Pressure Entrained-Flow (EF) Oxygen-Blown Gasifier Gasification of Coal/Biomass Mixtures. Office of Scientific and Technical Information (OSTI), September 2009. http://dx.doi.org/10.2172/1002145.

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