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Journal articles on the topic 'Poly (3+ people)'

Author: Grafiati

Published: 25 July 2024

Last updated: 31 July 2025

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1

Garfinkel, Doron. "Poly-de-prescribing to treat polypharmacy: efficacy and safety." Therapeutic Advances in Drug Safety 9, no. 1 (2017): 25–43. http://dx.doi.org/10.1177/2042098617736192.

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Background: The aim of this study was to evaluate efficacy and safety of poly-de-prescribing (PDP) based on the Garfinkel method in older people with polypharmacy. Methods: A longitudinal, prospective, nonrandomized study in Israel was carried out between 2009 and 2016. Comprehensive geriatric assessments were performed at home in people age ⩾66 years consuming ⩾6 prescription drugs. Exclusion criteria were life expectancy <6 months and a seeming unwillingness to cooperate (poor compliance). PDP of ⩾3 prescription drugs was recommended. Follow up was at ⩾3 years. Between April 2015 and Apri

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Zhao, Li, Li Yan Wang, and Guang Qing Gai. "The Glucose-Responsive Nanogel Based on Phenylboronic Acid." Applied Mechanics and Materials 680 (October 2014): 42–45. http://dx.doi.org/10.4028/www.scientific.net/amm.680.42.

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Diabetes mellitus, following cancer and cardiovascular disease, become one of the most serious diseases that threat to human health. The treatment of diabetes is imminent for the health of people. Thus, the developments of efficient insulin administration exhibit great practical significance. The glucose-responsive insulin delivery system (GRIDS) is developing rapidly which is expected to be a promising therapy approach to replace the frequent insulin injection administration. A novel glucose-responsive nanogel was conveniently prepared through one-pot copolymerization of pentaerythritol tetra

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Rambe, Normayanti. "Analysis Of The Need And Demand For Health Services At The Marsabut Lake Health Center, South Tapanuli Regency In The Jkn Era." Science Midwifery 10, no. 3 (2022): 2325–31. http://dx.doi.org/10.35335/midwifery.v10i3.646.

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The phenomenon of people preferring to seek treatment abroad instead of using domestic health services is a big challenge. This challenge can be answered by improving quality in all fields, especially the health sector. So, this is what will help health service providers in setting strategies to meet the needs of the community in the health sector. The purpose of the study was to determine the need, demand, and utility of public health services in the work area of the Marsabut Lake Health Center, South Tapanuli Regency. Types of quantitative research with a cross-sectional approach. The popula

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Al Maududi, Abul A'la, and Suherman Jaksa. "The Effect of Service Quality and Trust on Patient Satisfaction." Dinasti Health and Pharmacy Science 1, no. 4 (2024): 119–30. https://doi.org/10.38035/dhps.v1i4.378.

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The purpose of this study was to determine and analyze: (1) Service quality; (2) Trust; (3) Patient Satisfaction and (4) The effect of service quality performance and trust on patient satisfaction in the eye disease clinic of Santosa Hospital Bandung Central. The research method used in this research is descriptive survey and explanatory survey, the unit of analysis in this study is the Eye Disease Poly of Santosa Hospital Bandung Central with a sample of 50 people. The type of investigation is causality, and the time horizon in this study is cross-sectional.Based on the results of the study,

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YENER, Yeşim, and Fatma Hümeyra YERLİKAYA. "Western diet induces endogen oxidative deoxyribonucleic acid damage and infl ammation in Wistar rats." Revista de Nutrição 31, no. 3 (2018): 263–73. http://dx.doi.org/10.1590/1678-98652018000300001.

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ABSTRACT Objective Nutritional diseases such as metabolic syndrome, cardiovascular disorder, chronic inflammation or even cancer are observed in people who sustain their lifestyle by Western diet due to high calorie intake. The origin of these diseases are the degraded deoxyribonucleic acid structure. In this study, we investigated whether Western diet produced endogenous oxidative deoxyribonucleic acid damage, apoptosis or inflammation. Methods Twenty-eight male Wistar rats, aged 10-12 weeks, were divided into four groups. The rats in control group received the standard diet and the remaining

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Haifeng, Liu, Zhang Fan, Wu Huiming, Wang Qinglai, Zhang Kuixian, and Zeng Xiaoshuai. "Polydatin Alleviates Lipopolysaccharide-Triggered Inflammatory Injury Through Up-Regulating miR-125b in Chondrogenic ATDC5 Cells." Current Topics in Nutraceutical Research 18, no. 1 (2019): 108–14. http://dx.doi.org/10.37290/ctnr2641-452x.18:108-114.

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Osteoarthritis is a bone-joint disease prevalent in older people characterized by joint inflammation. In traditional Chinese medicine, polydatin plays an important anti-inflammatory role. This study analyzed the potential effects and possible internal mechanisms of polydatin on osteoarthritis. First, lipopolysaccharide-induced osteoarthritis injury was established in chondrogenic ATDC5 cells. Lipopolysaccharides significantly stimulated inflammatory injuries in ATDC5 cells as exemplified by a decrease in cell viability and an increase in inflammatory cytokine secretions including interleukin-6

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Sari, Yuli Permata. "Hubungan Program Pengobatan Kanker terhadap Konsep Diri Wanita dengan Carsinoma Mammae." Jurnal Keperawatan Silampari 3, no. 1 (2019): 211–20. http://dx.doi.org/10.31539/jks.v3i1.765.

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The purpose of this study was to study the relationship of treatment programs to self-concept in women with mammary carcinoma in the Polyclinic Surgery Clinic of RSUD Dr. Achmad Mochtar Bukittinggi. The design of this study uses descriptive analytic methods. The results of this study were obtained by more than half of respondents who undertook treatment programs at the poly surgical clinic of RSUD Dr. Achmad Mochtar Bukittinggi is 19 people (63.3%) and more than half obtained a low self-concept in women with carsinoma mammaes as many as 16 respondents (53, 3%) in the poly surgical clinic of Dr

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Hidayah, Hanna, Dewi Sodja Laela, Hera Nurnaningsih, and Deru Marah Laut. "Relationship Of Patient Knowledge Level About Wound Care After Molar Extraction 3 With The Success Of Patient Wound Care." Jurnal Terapi Gigi dan Mulut 2, no. 1 (2022): 14–20. http://dx.doi.org/10.34011/jtgm.v2i1.1258.

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Post-extraction of M3 tooth extraction is an effort to speed up the healing process and prevent and reduce pain and swelling. Pasien will be given instructions and education on how to take care of the possible tooth extractions. In-depth knowledge of the treatment of M3 tooth extraction wounds can be known in the instruction after removal. This study aims to determine the relationship between the level of patient knowledge about wound care after the removal of molars 3 with the success of wound care at the Dental and Oral Hospital, Padjadjaran University. This type of research is analytics. Th

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Frumina, S. V., and I. P. Khominich. "Today’s Finance Markets in Conditions of Poly-Crisis and Crisis of Cost of Living." Vestnik of the Plekhanov Russian University of Economics, no. 3 (May 23, 2024): 156–63. http://dx.doi.org/10.21686/2413-2829-2024-3-156-163.

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The article provides characteristics, statistics and factual material on countries connected with the current global economic crisis of the cost of living. The notion of the current poly-crisis was defined as a sum total of old and new risks in their close interaction and their adverse impact on global and national economy and finance markets. The focus was made on tightening of monetary and credit policy of national central banks in 2022–2023 in view of combating inflation, which resulted in more expensive credits, higher profitability of state treasury bonds, bankruptcy of corporations and d

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Duffney, Parker F., Claire E. McCarthy, Aitor Nogales, et al. "Cigarette smoke dampens antiviral signaling in small airway epithelial cells by disrupting TLR3 cleavage." American Journal of Physiology-Lung Cellular and Molecular Physiology 314, no. 3 (2018): L505—L513. http://dx.doi.org/10.1152/ajplung.00406.2017.

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Cigarette smokers and people exposed to second-hand smoke are at an increased risk for pulmonary viral infections, and yet the mechanism responsible for this heightened susceptibility is not understood. To understand the effect of cigarette smoke on susceptibility to viral infection, we used an air-liquid interface culture system and exposed primary human small airway epithelial cells (SAEC) to whole cigarette smoke, followed by treatment with the viral mimetic polyinosinic polycytidylic acid (poly I:C) or influenza A virus (IAV). We found that prior smoke exposure strongly inhibited productio

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Tait, Robert J., Rebecca McKetin, Frances Kay-Lambkin, et al. "A Web-Based Intervention for Users of Amphetamine-Type Stimulants: 3-Month Outcomes of a Randomized Controlled Trial." JMIR Mental Health 1, no. 1 (2014): e1. http://dx.doi.org/10.2196/mental.3278.

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Background Among illicit drugs, the prevalence of amphetamine-type stimulant (ATS) use is second only to cannabis. Currently, there are no approved pharmacotherapies for ATS problems, but some face-to-face psychotherapies are effective. Web-based interventions have proven to be effective for some substance use problems, but none has specifically targeted ATS users. Objective The objective of the study was to evaluate the effectiveness of a Web-based intervention for ATS problems on a free-to-access site compared with a waitlist control group. Methods We used a randomized controlled trial desig

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Atkinson, Irina, Ana Maria Seciu-Grama, Oana Catalina Mocioiu, et al. "Preparation and Biocompatibility of Poly Methyl Methacrylate (PMMA)-Mesoporous Bioactive Glass (MBG) Composite Scaffolds." Gels 7, no. 4 (2021): 180. http://dx.doi.org/10.3390/gels7040180.

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In recent years, the rising number of bone diseases which affect millions of people worldwide has led to an increased demand for materials with restoring and augmentation properties that can be used in therapies for bone pathologies. In this work, PMMA- MBG composite scaffolds containing ceria (0, 1, 3 mol%) were obtained by the phase separation method. The obtained composite scaffolds were characterized by X-ray diffraction, infrared spectroscopy, and scanning electron microscopy. UV–Vis measurement and EDX analysis confirmed the presence of cerium ions in the composite scaffolds. Evaluation

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Kisid, Kristiani, and Endy Bebasari Ardhana Putri. "KEJADIAN COVID-19 BERDASARKAN KARAKTERISTIK PENGUNJUNG POLI ISPA PUSKESMAS PERAMPUAN LOMBOK BARAT." Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram 7, no. 2 (2021): 169–75. http://dx.doi.org/10.33651/jpkik.v7i2.276.

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The Covid-19 pandemic, which began in early 2020, has affected more than 3 million people in Indonesia. All health services are mobilized for p revention and treatment. The Public Health Center of Perampuan in West Lombok is no exception, which carries out a screening program for suspected visitors as visitors. In mid-2021, when a new variant of covid-19 emerged, namely the delta variant, visitors to the Poli ISPA were known to experience an increase in their covid-19 status through the Rapid Diagnostic Test (RDT) antigen. The purpose of this study was to describe the characteristics of poly I

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Sampathi, Bharat R., Anna Sofine, John Alvarez, and Robert Bota. "Capgras syndrome in substance-induced psychosis." Mental Illness 10, no. 2 (2018): 38–39. http://dx.doi.org/10.1108/mi.2018.7807.

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Capgras Syndrome is a subcategory of delusional disorder. People affected by this syndrome believe that a close associate such as a friend or family member has been replaced by an identical imposter. This case report describes a 23-year-old woman with no prior psychiatric history, whom developed Capgras syndrome, via folie a deux, in the setting of poly-substance use. In this patient, a combination of Aripiprazole 10 mg daily and Escitalopram 10 mg daily were effective in resolving symptoms. Clonazepam was utilized for anxiety and Omega-3 fatty acids 1 g for anti-oxidative effects. Further stu

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Lundberg, Camilla Stub, Elisabeth Kvaavik, and Rikke Tokle. "Nye bruksmønstre i et tobakksmarked i endring – kombinert bruk av sigaretter, snus og e-sigaretter blant ungdom." Nordic Studies on Alcohol and Drugs 36, no. 1 (2018): 6–20. http://dx.doi.org/10.1177/1455072518797823.

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Objectives: There is limited research on combined use of cigarettes, snus and e-cigarettes in the Nordic countries. This study will investigate whether this pattern of use occurs among adolescents in Norway. In addition, we will investigate the association between combined use of several tobacco products, e-cigarettes and socio-demographic and psychosocial factors (SPF). Method: A school-based cross-sectional survey of adolescents in the 8th to the 12th grade ( N = 875) in 2014. Information on the use of cigarettes, snus, e-cigarettes and SPF was collected using an electronic questionnaire. Re

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Vallecillo, Gabriel, Alejandra Losada, Alexy Inciarte, et al. "Increasing emergency department admissions for chemsex-related intoxications in Barcelona, Spain, among people living with HIV: an observational study from 2018 to 2020." BMC Public Health 22 (February 18, 2022): 346. https://doi.org/10.1186/s12889-022-12763-3.

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Background Chemsex is a novel phenomenon referring to the use of drugs, including crystal methamphetamine, gammahydroxybutyric acid (GHB)/gamma-butyrolactone (GABA) and mephedrone, to facilitate, enhance, and prolong the sexual experience in men who have sex with men in large cities internationally. There is a growing concern about chemsex and fatal cases among people living with HIV on antiretroviral therapy. This study aimed to describe the clinical characteristics of chemsex-related intoxications. Material and methods An observational study was conducted in people living with HIV who were a

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Liu, Yaohui, Yanming Wang, Cheng-Hao Lee, Chi-Wai Kan, and Xiaoying Lu. "Influence of Electrospinning Parameters on the Morphology of Electrospun Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Fibrous Membranes and Their Application as Potential Air Filtration Materials." Polymers 16, no. 1 (2024): 154. http://dx.doi.org/10.3390/polym16010154.

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A large number of non-degradable materials have severely damaged the ecological environment. Now, people are increasingly pursuing the use of environmentally friendly materials to replace traditional chemical materials. Polyhydroxyalkonates (PHAs) are receiving increasing attention because of the unique biodegradability and biocompatibility they offer. However, the applications of PHAs are still limited due to high production costs and insufficient study. This project examines the optimal electrospinning parameters for the production of PHA-based fibrous membranes for air filtration. A common

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Fitzpatrick, John-Mark, Becky Hackett, Lisa Costelloe, William Hind та Eric J. Downer. "Botanically-Derived Δ9-Tetrahydrocannabinol and Cannabidiol, and Their 1:1 Combination, Modulate Toll-like Receptor 3 and 4 Signalling in Immune Cells from People with Multiple Sclerosis". Molecules 27, № 6 (2022): 1763. http://dx.doi.org/10.3390/molecules27061763.

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The innate immune response to bacterial and viral molecules involves the coordinated production of cytokines, chemokines, and type I interferons (IFNs), which is orchestrated by toll-like receptors (TLRs). TLRs, and their intracellular signalling intermediates, are closely associated with multiple sclerosis (MS) pathogenesis. Recent data from our laboratory reported that the plant-derived cannabinoids, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD), regulate viral and bacterial inflammatory signalling pathways controlled by TLR3 and TLR4 in macrophages. The aim of this study was to assess

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Novozhylova, I. O., and I. V. Bushura. "Risks of recurrence in people with pulmonary tuberculosis." Infusion & Chemotherapy, no. 3 (September 29, 2023): 24–30. http://dx.doi.org/10.32902/2663-0338-2023-3-24-30.

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OBJECTIVE. To assess the risk of relapse in patients with pulmonary tuberculosis (PTB). MATERIALS AND METHODS. 569 people with relapsed PTB (RPTB) were selected from the TB register (e-TB manager programme): 300 with a first case treatment outcome of “completed treatment” and 269 “cured”. The groups were compared according to the course and outcome of treatment of RPTB, clinical characteristics of the first case, medical and social risk factors, and all patients with RPTB were compared with the group of newly diagnosed PTB (NDPTB). Mathematical and conventional statistical methods were u

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Silvestre, Isabel, Maria Marshall, Kathryn Hagen, et al. "Characterization of the therapeutic increases in natural killer (NK) activity of xenotropic murine leukemia virus-related virus (XMRV)-positive chronic fatigue syndrome (CFS) patients effected by poly (I): poly (C12U) (Ampligen) (89.49)." Journal of Immunology 184, no. 1_Supplement (2010): 89.49. http://dx.doi.org/10.4049/jimmunol.184.supp.89.49.

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Abstract Chronic Fatigue Syndrome (CFS) is a debilitating disease of unknown etiology that affects ~17 million people worldwide. Patients suffer persistent viral infections and may develop hematopoietic malignancies. The patients have reduced Natural Killer (NK) cell activities which could contribute to the diseases, and, if restored, potentially reduce symptoms. We characterized the in vitro effects on NK cells of the interferon inducer poly (I): poly (C12U) (Ampligen) which in some CFS patients abates disease symptoms. The 30 CFS patients were infected with the gammaretrovirus xenotropic mur

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Bessarab, Anastasiia, Tetiana Hyrina, Irina Antonenko, and Yana Zoska. "THE ROLE OF MASS COMMUNICATION IN THE SOCIALIZATION OF PEOPLE WITH DISABILITIES IN UKRAINE." Social Communications: Theory and Practice 11, no. 2 (2020): 158–69. http://dx.doi.org/10.51423/2524-0471-2020-11-2-10.

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The purposeof the study is to formulate an overall picture of the role of mass communication in the socialization of people with disabilities through social communication project initiatives in Ukraine.The achievement ofthis goal included the fulfillment of the following tasks: analysis of sources on thistopic; questioning and establishing the primary information and communication needs of persons with disabilities as a media audience through an expert survey.Research methods and techniques. During the researchwhen elaborating the sources on the topic there were used the methods of analysis, s

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Rahmiyati, Ayu Laili, and Raudha Setyanti. "ANALISIS TARIF POLI UMUM BERDASARKAN ABILITY TO PAY (ATP) DAN WILLINGNESS TO PAY (WTP) DI KLINIK PRATAMA MEDICA ZAHRA BANDUNG TAHUN 2022." Prosiding Seminar Sosial Politik, Bisnis, Akuntansi dan Teknik 5 (December 9, 2023): 131. http://dx.doi.org/10.32897/sobat.2023.5.0.3089.

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General poly patient visits in the last 3 months showed a decrease of 27%.Objective This research aims to analyze the willingness and ability to pay for General Polyclinic patients at the Pratama Medica Zahra Clinic. Research methods quantitatively and qualitatively. Data collection is by questionnaire with Google Form, interviews, observation and document review.Research result namely the respondent's ATP (Ability To Pay) of Rp. 114,000,- while most respondents chose the rate set by the clinic as the lowest category rate, namely Rp. 45,000 – Rp. 50,000,- it has been confirmed that almost all

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LI, C., S. Lin, Z. Ouyang, et al. "POS0333 NLRP12 EXACERBATES OSTEOARTHRITIS BY PROMOTING DEGRADATION OF NOD2 IN SYNOVIAL MACROPHAGES." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 412.2–413. http://dx.doi.org/10.1136/annrheumdis-2023-eular.749.

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BackgroundOsteoarthritis is the most common degenerative bone and joint disease. Hypothesis has been widely accepted that osteoarthritis (OA) starts from cartilage injury and loss, while emerging evidences suggest that synovial inflammation precedes cartilage loss during the progression of OA [1]. Activation of macrophages plays a crucial part in synovial inflammation in OA [2]. In our previous researches, we have demonstrated NOD2 as an inhibitor of macrophage activationin vitro. Besides, bioinformatic analysis suggested a potential link between NLRP12 and NOD2.ObjectivesTo investigate the ro

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Wati, Del Fatma, and Yusda Yanti. "GAMBARAN DUKUNGAN KELUARGA TERHADAP PERUBAHAN KONSEP DIRI PASIEN PASCA STROKE DI POLI NEUROLOGI HANAFIAH BATUSANGKAR." Real in Nursing Journal 1, no. 1 (2018): 20. http://dx.doi.org/10.32883/rnj.v1i1.225.

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<p><em>Stroke can affect all aspects of personal, social, physical, psychological, patients in doing something that is usually done before a stroke, so often show attitudes and behavior such as there is no hope and feel isolated. Initial survey of 5 patients after stroke, 2 people treated with other people because their families could not accompany, 3 people felt inferior in the environment because of their physical limitations. The purpose of this study was to describe the family support with changes in self-concept of post-stroke patients. The design of this study uses qualitativ

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Wieshmann, UC, A. Chawira, S. Keller, and G. Baker. "TP3-1 Memory impairment in epilepsy." Journal of Neurology, Neurosurgery & Psychiatry 90, no. 3 (2019): e18.1-e18. http://dx.doi.org/10.1136/jnnp-2019-abn.56.

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ObjectivesMemory impairment is an extremely common complaint in people with epilepsy (PWE). The purpose of our cross sectional study was to identify factors associated with self-reported memory impairment in PWE.Methods514 PWE and 52 controls completed the Liverpool Adverse Event Profile, a 19 item questionnaire which includes items on memory and depression and provided clinical data on age, sex, medication, seizure onset, frequency and severity. For memory impairment, sleep disturbance, depression and seizure type scores were dichotomised into minor deficits (Likert scores 1 and 2), and major

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Renylda, Reta. "KECEMASAN ORANG TUA PADA ANAK DENGAN THALASEMIA DI POLI ANAK RUMAH SAKIT UMUM DAERAH H. ABDUL MANAP KOTA JAMBI TAHUN 2015." Jurnal Ilmiah Universitas Batanghari Jambi 18, no. 1 (2018): 110. http://dx.doi.org/10.33087/jiubj.v18i1.438.

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Children with thalassemia must undergo blood transfusions to sustain life and routinely done in periods of continuous lama.Pengobatan will have an impact on psychosocial problems in the family, especially in the elderly. Parents will face a backlash in any care and treatment such as guilt, anxiety, fear, sadness, economic problems and worry about not getting the proper care and treatment.This research is a quantitative descriptive research that aims to describe the level of anxiety of parents of children with thalassemia in Poly Children's Hospital. H. Abdul Manap Jambi City in 2015. The popul

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Nurmawati, Thatit, Yeni Kartika Sari, and Aprilia Putri Hidayat. "Evaluation of CD4 Number In HIV / AIDS Patients Who Are Running The Antiretrovial Treatment Program." Journal of Agromedicine and Medical Sciences 6, no. 2 (2020): 77. http://dx.doi.org/10.19184/ams.v6i2.16790.

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HIV is a health problem for Indonesia and the world. Enforcement of diagnoses and control efforts continue to be made to reduce the number of HIV / AIDS cases. ARVs are becoming efforts to cure HIV by increasing CD4 cell counts. CD4 cell count is a determinant of ARV therapy. The purpose of this study was to evaluate CD4 cell counts in people with HIV / AIDS who were implementing ARV programs. The study design was observational using secondary data in the form of medical record records. The study population was HIV sufferers who registered to run an HIV / AIDS antiretrovial treatment program a

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DellaCrosse, Meghan, Mollie Pleet, Emma Morton, et al. "“A sense of the bigger picture:” A qualitative analysis of follow-up interviews with people with bipolar disorder who self-reported psilocybin use." PLOS ONE 17, no. 12 (2022): e0279073. http://dx.doi.org/10.1371/journal.pone.0279073.

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Objectives People with bipolar disorder (BD) spend more time depressed than manic/hypomanic, and depression is associated with greater impairments in psychosocial functioning and quality of life than mania/hypomania. Emerging evidence suggests psilocybin, the psychoactive compound in “magic mushrooms,” is a promising treatment for unipolar depression. Clinical trials of psilocybin therapy have excluded people with BD as a precaution against possible adverse effects (e.g., mania). Our study centered the experiences of adults living with BD who consumed psilocybin-containing mushrooms, and aimed

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Sunarti, Sunarti, Imam Sunarno, and Alvino Alvino. "Upaya Penderita Hipertensi untuk Mempertahankan Pola Hidup Sehat." Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 2, no. 2 (2015): 120–24. http://dx.doi.org/10.26699/jnk.v2i2.art.p120-124.

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Healthy lifestyle is a lifestyle with attention to factors - certain factors that affect health, such as diet and exercise. The purpose of this research is to identify how the efforts of patients hypertension to maintain a healthy lifestyle. Methods this research uses descriptive design. The population in this research were all patients with hypertension in Poly UPTD Kesehatan Kecamatan Sukorejo Blitar total of 220 people, the number of samples in this study were 33 respondents and using purposive sampling technique. Data collection is done by giving questionnaires. Time of data collection was

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Sunarti, Sunarti, Imam Sunarno, and Alvino Alvino. "Hypertension Patients Efforts to Maintain Healthy Lifestyles." Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 2, no. 2 (2015): 115–19. http://dx.doi.org/10.26699/jnk.v2i2.art.p115-119.

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Healthy lifestyle is a lifestyle with attention to factors - certain factors that affect health, such as diet and exercise. The purpose of this research is to identify how the efforts of patients hypertension to maintain a healthy lifestyle. Methods this research uses descriptive design. The population in this research were all patients with hypertension in Poly UPTD Kesehatan Kecamatan Sukorejo Blitar total of 220 people, the number of samples in this study were 33 respondents and using purposive sampling technique. Data collection is done by giving questionnaires. Time of data collection was

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Bazarnyi, V. V., M. A. Kopenkin, L. G. Polushina, A. Yu Maximova, E. A. Sementsova, and Yu V. Mandra. "Significance of salivary poly (ADP-ribose)-polymerase in the assessment of age-dependent pathological processes in the oral cavity." Biomeditsinskaya Khimiya 69, no. 2 (2023): 125–32. http://dx.doi.org/10.18097/pbmc20236902125.

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Age-related changes in the oral cavity are accompanied by the development of age-related pathology, such as chronic periodontitis (CP). Although apoptosis plays a certain role in its pathogenesis, this fact, however, has not been evaluated clinically, and the diagnostic information content of biomarkers of apoptosis and aging has not been determined. The aim of the study was to evaluate the content of cleaved poly-(ADP-ribose)-polymerase (cPARP) and caspase-3 (Casp3) in mixed saliva of elderly patients with age-related dental diseases and in mature patients with mild to moderate CP. The study

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Vincent van, Ginneken. "The Expected Pandemic of Mild-Alzheimer (≈Type 3 Diabetes), How to Combat?" Gastroenterology & Hepatology International Journal 4, no. 2 (2019): 1–10. http://dx.doi.org/10.23880/ghij-16000157.

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With the increasing aging of the world population, the share in the population with mild Alzheimer's (m-ADs) - also referred to as type-3 diabetes - is increasing. Rough estimates indicate that by 2050 around 140 million people will suffer from this disease, especially in developed countries but with an increasing morbidity in Low- and Middle-Income countries. m-ADs can be characterized by senile plaques that consist of extracellular amyloid beta (Aβ) deposition while neurofibrillary tangles (NFT) -consisting of hyperphosphorylated tau which are located intracellular in Alzheimer Diseased brai

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Hu, P., B. Ming, X. Wu, and L. Dong. "AB0131 RESPIRATORY TRACT POLY(I:C) STIMULATION ACCELERATES SALIVARY GLAND IMMUNE DYSFUNCTION IN SPONTANEOUS SJOGREN’S SYNDROME ANIMAL MODEL." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1366.1–1367. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3433.

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Background:Sjogren’s syndrome is one of the most common autoimmune diseases, with a prevalence of 0.33% to 0.77% in Chinese people, characterized by focal infiltration of lymphocytes in glands and the production of multiple autoantibodies. Studies have shown that virus infection may play a crucial role in the occurrence and development of this disease.Objectives:It has been shown that airway stimulation with poly(I:C) can mimic respiratory tract viral infection to some extent. Thus, this study was aimed to investigate the dynamic immune responses in salivary gland after respiratory tract poly(

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Bruter, Michael. "Electoral Ergonomics: Three Empirical Examples of the Interface between Electoral Psychology and Design." Societies 9, no. 4 (2019): 82. http://dx.doi.org/10.3390/soc9040082.

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Electoral ergonomics pertains to the interface between electoral psychology and electoral design. It moves beyond traditional models of electoral organisation that often focus on mechanical effects or changes to who actually votes to investigate the ways in which different forms of electoral organisation will switch on and off various electoral psychology buttons (in terms of personality, memory, emotions and identity) so that the very same person’s electoral experience, thinking process, and ultimately electoral behaviour will change based on the design of electoral processes. This article il

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Hidayah, Alfina Okta Nur, Marsudi, and Sri Nastiti Andharini. "Influence of Experiential Marketing on Patient Loyalty Through Patient Satisfaction as Intervening Variable." Business Innovation Management and Entrepreneurship Journal (BIMANTARA) 2, no. 01 (2023): 44–54. http://dx.doi.org/10.22219/bimantara.v2i01.27250.

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This study aimed to analyze and describe the effect of experiential marketing, patient satisfaction, and patient loyalty at As-Syifa Husada Clinic. This research uses quantitative research. The population of this study is people who are currently or have used the services of the As-Syifa Husada Clinic, and the sample is 110 respondents who have used the services of the KIA Poly (Mother & Child Clinic) at least two times. Data collection techniques in this study used a questionnaire distributed to respondents. The analytical method used is path analysis and hypothesis testing using T-test a

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Chong, Kok Chung, Soon Onn Lai, Hui San Thiam, Shee Keat Mah, Woei Jye Lau, and Ahmad Fauzi Ismail. "Performance Evaluation of PDMS or PEBAX-Coated Polyetherimide Membrane for Oxygen/Nitrogen Separation." Sains Malaysiana 50, no. 11 (2021): 3395–404. http://dx.doi.org/10.17576/jsm-2021-5011-23.

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Since the industrial revolution era, the Earth was suffering from serious air pollution. Millions of people are now suffering from indoor air pollution related diseases, especially in the industrialized countries such as China. One method to improve the indoor air quality is by oxygen enhancement. Membrane technology has been a key research over the past decades due to its low energy usage, minimum chemical consumption as well as small setting up layout. In this study, polyetherimide (PEI) membranes coated with polydimethylsiloxane (PDMS) or poly(ether block amide) (PEBAX) at different concent

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Lestari, Heni, Lolita Sary, and Andoko Andoko. "Analisis Faktor Pemungkin Terhadap Rendahnya Pemanfaatan Pelayanan Poli Gigi." MAHESA : Malahayati Health Student Journal 1, no. 1 (2021): 40–52. http://dx.doi.org/10.33024/mahesa.v1i1.3318.

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ABSTRACT : ANALYSIS OF IMPORTANT FACTORS ON THE LOW UTILIZATION OF DENTAL POLICE SERVICES AT PUSKESMAS REBANG TANGKAS WAY KANAN Introduction: Dental polyclinic service is one of the types of services in a public health center that provides dental and oral health services in the form of dental and oral health checks, medication and provision of basic dental and oral health medical measures. The results of the pre-survey in the working area of Puskemas Rebang Tangkas, Way Kanan Regency towards 10 respondents, 7 of whom prefer to seek treatment at a dentist or a dental clinic. Meanwhile, 3 of the

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Menegatto, Marialuisa, Sara Lezzi, Michele Musolino, and Adriano Zamperini. "The Psychological Impact of Per- and Poly-Fluoroalkyl Substances (PFAS) Pollution in the Veneto Region, Italy: A Qualitative Study with Parents." International Journal of Environmental Research and Public Health 19, no. 22 (2022): 14761. http://dx.doi.org/10.3390/ijerph192214761.

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Little is known about the psychosocial impact on people who live in polluted areas, and its consequences for the parental role have been neglected. This study addresses this gap, proposing qualitative research referring to the case of per- and poly-fluoroalkyl substances (PFAS) water pollution in the Veneto Region of Italy. The purpose of this study was to investigate the chronic exposure contamination (CEC) experience of parents. Semi-structured interviews were conducted with 32 parents living in the so-called ‘Red Area’ considered to have had maximum exposure. Grounded theory was used to ana

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A.A.A, Niti Wedayani, Dedianto Hidajat, and Dini Ramdhani. "Pengenalan dan Edukasi Penyakit Kusta (Morbus Hansen) di RSUD Manambae, Sumbawa Besar." Jurnal Gema Ngabdi 4, no. 1 (2022): 85–89. http://dx.doi.org/10.29303/jgn.v4i1.231.

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Background: Morbus Hansen (Leprosy) is a skin health problem that is still often found in the people of West Nusa Tenggara. Leprosy is caused by various factors, including personal hygiene, water conditions, and nutrition. In addition to being infected by Micobacterium Leprae itself, hygiene factors and initial therapy will determine the success of treatment and the prognosis of the disease which will then affect the health and quality of life of the community. In the research that has been done, it is said that leprosy in Indonesian society, especially Nusa Tenggara, is still very large, even

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Scarborough, Joseph, Daniele Mattei, Cornelia Dorner-Ciossek, et al. "Symptomatic and preventive effects of the novel phosphodiesterase-9 inhibitor BI 409306 in an immune-mediated model of neurodevelopmental disorders." Neuropsychopharmacology 46, no. 8 (2021): 1526–34. http://dx.doi.org/10.1038/s41386-021-01016-3.

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AbstractBI 409306, a phosphodiesterase-9 inhibitor under development for treatment of schizophrenia and attenuated psychosis syndrome (APS), promotes synaptic plasticity and cognition. Here, we explored the effects of BI 409306 treatment in the polyriboinosinic-polyribocytidilic acid (poly[I:C])-based mouse model of maternal immune activation (MIA), which is relevant to schizophrenia and APS. In Study 1, adult offspring received BI 409306 0.2, 0.5, or 1 mg/kg or vehicle to establish an active dose. In Study 2, adult offspring received BI 409306 1 mg/kg and/or risperidone 0.025 mg/kg, risperido

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Serafeim, Adamantios, Michelle J. Holder, Gillian Grafton, et al. "Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells." Blood 101, no. 8 (2003): 3212–19. http://dx.doi.org/10.1182/blood-2002-07-2044.

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Abstract Selective serotonin reuptake inhibitors (SSRIs) are the treatment of choice for clinical depression and a range of anxiety-related disorders. They are well tolerated over extended periods with more than 50 million people worldwide benefiting from their use. Here we show that 3 structurally distinct SSRIs—fluoxetine, paroxetine, and citalopram—act directly on Burkitt lymphoma (BL) cells to trigger rapid and extensive programmed cell death. SSRIs unexpectedly stimulated calcium flux, tyrosine phosphorylation, and down-regulation of the c-myc and nm23 genes in Burkitt lymphoma cells rema

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Eko Saputro and Ersa Tri Fitriasari. "Perlakuan Balita Dengan Manajemen Terpadu Balita Sakit (MTBS) Di Puskesmas Sukadana." J-CEKI : Jurnal Cendekia Ilmiah 1, no. 2 (2022): 85–93. http://dx.doi.org/10.56799/jceki.v1i2.147.

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To provide standard services in Public Health Center takes a commitment from the Head of the Public Health Center and the commitment of the doctors as a motivator for nurses and midwives in addition to being a supervisor and receiving referrals. The continuity of the implementation of IMCI services is to maintain and to improve the quality of IMCI services by remaining consistent in improving the health facilities of the Public Health Center so that people who are far from the Public Helath Center can get the standard IMCI services and continue to innovate in developing utilization by developi

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Ambagtsheer, Rachel C., Renuka Visvanathan, Elsa Dent, Solomon Yu, Timothy J. Schultz, and Justin Beilby. "Commonly Used Screening Instruments to Identify Frailty Among Community-Dwelling Older People in a General Practice (Primary Care) Setting: A Study of Diagnostic Test Accuracy." Journals of Gerontology: Series A 75, no. 6 (2019): 1134–42. http://dx.doi.org/10.1093/gerona/glz260.

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Abstract Background Rapid frailty screening remains problematic in primary care. The diagnostic test accuracy (DTA) of several screening instruments has not been sufficiently established. We evaluated the DTA of several screening instruments against two reference standards: Fried’s Frailty Phenotype [FP] and the Adelaide Frailty Index [AFI]), a self-reported questionnaire. Methods DTA study within three general practices in South Australia. We randomly recruited 243 general practice patients aged 75+ years. Eligible participants were 75+ years, proficient in English and community-dwelling. We

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Kuo, Tsu-Jen, Yen-Hsuan Jean, Po-Chang Shih, et al. "Stellettin B-Induced Oral Cancer Cell Death via Endoplasmic Reticulum Stress–Mitochondrial Apoptotic and Autophagic Signaling Pathway." International Journal of Molecular Sciences 23, no. 15 (2022): 8813. http://dx.doi.org/10.3390/ijms23158813.

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Oral squamous cell carcinoma (OSCC) affects tens of thousands of people worldwide. Despite advances in cancer treatment, the 5-year survival rate of patients with late-stage OSCC is low at 50–60%. Therefore, the development of anti-OSCC therapy is necessary. We evaluated the effects of marine-derived triterpene stellettin B in human OC2 and SCC4 cells. Stellettin B dose-dependently decreased the viability of both cell lines, with a significant reduction in OC2 cells at ≥0.1 µM at 24 and 48 h, and in SCC4 cells at ≥1 µM at 24 and 48 h. Terminal deoxynucleotidyl transferase dUTP nick-end labelin

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Vigani, Barbara, Caterina Valentino, Valeria Cavalloro, et al. "Gellan-Based Composite System as a Potential Tool for the Treatment of Nervous Tissue Injuries: Cross-Linked Electrospun Nanofibers Embedded in a RC-33-Loaded Freeze-Dried Matrix." Pharmaceutics 13, no. 2 (2021): 164. http://dx.doi.org/10.3390/pharmaceutics13020164.

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Injuries to the nervous system affect more than one billion people worldwide, and dramatically impact on the patient’s quality of life. The present work aimed to design and develop a gellan gum (GG)-based composite system for the local delivery of the neuroprotective sigma-1 receptor agonist, 1-[3-(1,1′-biphen)-4-yl] butylpiperidine (RC-33), as a potential tool for the treatment of tissue nervous injuries. The system, consisting of cross-linked electrospun nanofibers embedded in a RC-33-loaded freeze-dried matrix, was designed to bridge the lesion gap, control drug delivery and enhance axonal

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Pires, Tomás, Andreia Sofia Oliveira, Ana Clara Marques, et al. "Effects of Non-Conventional Sterilisation Methods on PBO-Reinforced PVA Hydrogels for Cartilage Replacement." Gels 8, no. 10 (2022): 640. http://dx.doi.org/10.3390/gels8100640.

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Articular cartilage (AC) degradation is a recurrent pathology that affects millions of people worldwide. Polyvinyl alcohol (PVA) hydrogels have been widely explored for AC replacement. However, their mechanical performance is generally inadequate, and these materials need to be reinforced. Moreover, to be used in a clinical setting, such materials must undergo effective sterilisation. In this work, a PVA hydrogel reinforced with poly(p-phenylene-2,6-benzobisoxazole) (PBO) nanofibres was submitted to three non-conventional sterilisation methods: microwave (MW), high hydrostatic pressure (HHP),

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Sulistyowati, Dwi, and Rita Benya Adriani. "The Effect of Vasten Puki Yoga on Reduction of Incontinence in the Elderly." Indonesian Journal of Global Health Research 7, no. 2 (2025): 875–82. https://doi.org/10.37287/ijghr.v7i2.5453.

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Urinary incontinence is defined by the international continence society as a condition where uncontrollable urine output is a social or hygienic problem in the elderly and can be objectively proven. This study is looking for a model of gymnastic movements that are suitable for overcoming incontinence in the elderly, in the first year looking for gymnastic movements and getting a Vasten Puki Yoga gymnastics model that can be used as one of the effective interventions to control incontinence, which has been tested on elderly people in 5 elderly homes and get significant results without finding d

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Zhang, Sheng, Michael J. Carper, Xiaoyong Lei, W. Todd Cade, Kevin E. Yarasheski та Sasanka Ramanadham. "Protease inhibitors used in the treatment of HIV+ induce β-cell apoptosis via the mitochondrial pathway and compromise insulin secretion". American Journal of Physiology-Endocrinology and Metabolism 296, № 4 (2009): E925—E935. http://dx.doi.org/10.1152/ajpendo.90445.2008.

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Inclusion of HIV protease inhibitors (PIs) in the treatment of people living with HIV+ has markedly decreased mortality but also increased the incidence of metabolic abnormalities, causes of which are not well understood. Here, we report that insulinopenia is exacerbated when Zucker fa/fa rats are exposed to a PI for 7 wk, suggesting that chronic PI exposure adversely affects pancreatic islet β-cell function. In support of this possibility, we find increased apoptosis, as reflected by TUNEL fluorescence analyses, and reduced insulin-secretory capacity in insulinoma cells and human pancreatic i

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Mahadev, Manohar, Akhilesh Dubey, and Amitha Shetty. "Ultrasonically Fabricated Beta-Carotene Nanoemulsion: Optimization, Characterization and Evaluation of Combinatorial Effect with Quercetin on Streptozotocin-Induced Diabetic Rat Model." Pharmaceutics 15, no. 2 (2023): 574. http://dx.doi.org/10.3390/pharmaceutics15020574.

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Diabetes mellitus (D.M.) is a metabolic disease that has affected over 500 million people globally. Bioactive compounds such as β-carotene and Quercetin have gained research interest for their potential antidiabetic properties, and bioactives have reported superior combinatorial effects in several ailments, including D.M. However, poor oral bioavailability has limited their potential application. Thus, the present study was focused on developing ultrasonically fabricated β-Carotene nanoemulsion (βC-NE) by employing capmul as the oil phase, Gelucire 44/14 as surfactant and Acconon MCM C8 as co-

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Wijaya, Andriana Putri, Ulfa Dwi Arizka, and Ratna Dwi Wulandari. "Cross-sector Collaboration With HIV NGOs At Kedungdoro Primary Health Care." Open Access Health Scientific Journal 6, no. 1 (2025): 96–103. https://doi.org/10.55700/oahsj.v6i1.70.

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Background: Indonesia is the country with the 3rd highest number of new HIV cases in Asia Pacific after India and China. Surabaya is the city with the most HIV cases discovered with 1,260 cases. The indicator of the success of the HIV program is related to the number of people with new HIV who are found and given treatment, namely 43 out of 63 (68.25%) Primary Health Cares, the number of findings is less than the average for Primary Health Cares in Surabaya City, namely 8 PLHIV in 2023. Kedungdoro Health Center is a health center with the highest number of people with new HIV discovered and gi

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