Relevant bibliographies by topics / Poly-ic

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  1. Journal articles
  2. Dissertations / Theses
  3. Conference papers

Academic literature on the topic 'Poly-ic'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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Journal articles on the topic "Poly-ic"

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Packard, Amy E. B., Jason C. Hedges, Frances R. Bahjat, et al. "Poly-IC Preconditioning Protects against Cerebral and Renal Ischemia-Reperfusion Injury." Journal of Cerebral Blood Flow & Metabolism 32, no. 2 (2011): 242–47. http://dx.doi.org/10.1038/jcbfm.2011.160.

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Preconditioning induces ischemic tolerance, which confers robust protection against ischemic damage. We show marked protection with polyinosinic polycytidylic acid (poly-IC) preconditioning in three models of murine ischemia-reperfusion injury. Poly-IC preconditioning induced protection against ischemia modeled in vitro in brain cortical cells and in vivo in models of brain ischemia and renal ischemia. Further, unlike other Toll-like receptor (TLR) ligands, which generally induce significant inflammatory responses, poly-IC elicits only modest systemic inflammation. Results show that poly-IC is
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Lee, Li-Ting, Sheng-Ping He, and Chih-Feng Huang. "Enhancement of Crystallization Behaviors in Quaternary Composites Containing Biodegradable Polymer by Supramolecular Inclusion Complex." Crystals 10, no. 12 (2020): 1137. http://dx.doi.org/10.3390/cryst10121137.

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Novel multi-component composites composed of the biodegradable polymer poly(ethylene adipate) (PEA), the water-soluble polymer poly(ethylene oxide) (PEO), poly(vinyl acetate) (PVAc), and a supramolecular-like inclusion complex (IC) made by α-cyclodextrin (α-CD) and poly(ε-caprolactone) (PCL) (coded as PCL–CD–IC) are discussed in this work. The PCL–CD–IC was used to increase the crystallization rate of the miscible PEA/PEO/PVAc ternary blend that crystalized slower than neat PEA. Higher resolution SEM and TEM images displayed that PCL–CD–IC did not assemble notably in the quaternary composites.
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Lauterbach, Henning, Barbara Bathke, Stefanie Gilles та ін. "Mouse CD8α+ DCs and human BDCA3+ DCs are major producers of IFN-λ in response to poly IC". Journal of Experimental Medicine 207, № 12 (2010): 2703–17. http://dx.doi.org/10.1084/jem.20092720.

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Polyinosinic:polycytidylic acid (poly IC), a double-stranded RNA, is an effective adjuvant in vivo. IFN-λs (also termed IL-28/29) are potent immunomodulatory and antiviral cytokines. We demonstrate that poly IC injection in vivo induces large amounts of IFN-λ, which depended on hematopoietic cells and the presence of TLR3 (Toll-like receptor 3), IRF3 (IFN regulatory factor 3), IRF7, IFN-I receptor, Fms-related tyrosine kinase 3 ligand (FL), and IRF8 but not on MyD88 (myeloid differentiation factor 88), Rig-like helicases, or lymphocytes. Upon poly IC injection in vivo, the IFN-λ production by
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Luo, Xuelian, Dawei Ling, Ting Li, Chao Wan, Chuyu Zhang та Zishu Pan. "Classical swine fever virus Ernsglycoprotein antagonizes induction of interferon-β by double-stranded RNA". Canadian Journal of Microbiology 55, № 6 (2009): 698–704. http://dx.doi.org/10.1139/w09-013.

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Classical swine fever virus (CSFV) is capable of counteracting innate cellular antiviral responses by inhibiting type I interferon (IFN)-α/β induction. A function associated with CSFV Npro, with respect to the inhibition of IFN-β production, has been clearly elucidated. In this study, we explored the role of CSFV Ernsin IFN-β induction by exogenous double-stranded (ds) RNA. Synthetic dsRNA (poly (IC)) was used as an exogenous stimulus to trigger IFN-β induction. CSFV Ernsinhibited IFN-β promoter-driven luciferase activity induced by poly (IC) in different cell lines, and the inhibitory effect
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Padalko, Elizaveta, Dieter Nuyens, Armando De Palma, et al. "The Interferon Inducer Ampligen [Poly(I)-Poly(C12U)] Markedly Protects Mice against Coxsackie B3 Virus-Induced Myocarditis." Antimicrobial Agents and Chemotherapy 48, no. 1 (2004): 267–74. http://dx.doi.org/10.1128/aac.48.1.267-274.2004.

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ABSTRACT Viral replication, as well as an immunopathological component, is assumed to be involved in coxsackie B virus-induced myocarditis. We evaluated the efficacy of the interferon inducer Ampligen on coxsackie B3 virus-induced myocarditis in C3H/HeNHsd mice. The efficacy of Ampligen was compared with that of the interferon inducer poly(inosinic acid)-poly(cytidylic acid) [poly(IC)], alpha interferon 2b (INTRON A), and pegylated alpha interferon 2b (PEG-INTRON-α-2b). Ampligen at 20 mg/kg of body weight/day was able to reduce the severity of virus-induced myocarditis, as assessed by morphome
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Ruggli, Nicolas, Jon-Duri Tratschin, Matthias Schweizer, Kenneth C. McCullough, Martin A. Hofmann, and Artur Summerfield. "Classical Swine Fever Virus Interferes with Cellular Antiviral Defense: Evidence for a Novel Function of Npro." Journal of Virology 77, no. 13 (2003): 7645–54. http://dx.doi.org/10.1128/jvi.77.13.7645-7654.2003.

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ABSTRACT Classical swine fever virus (CSFV) replicates efficiently in cell lines and monocytic cells, including macrophages (MΦ), without causing a cytopathic effect or inducing interferon (IFN) secretion. In the present study, the capacity of CSFV to interfere with cellular antiviral activity was investigated. When the porcine kidney cell line SK-6 was infected with CSFV, there was a 100-fold increased capacity to resist to apoptosis induced by polyinosinic-polycytidylic acid [poly(IC)], a synthetic double-stranded RNA. In MΦ, the virus infection inhibited poly(IC)-induced alpha/beta IFN (typ
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Martins, Karen AO, Sina Bavari, and Andres M. Salazar. "Vaccine adjuvant uses of poly-IC and derivatives." Expert Review of Vaccines 14, no. 3 (2014): 447–59. http://dx.doi.org/10.1586/14760584.2015.966085.

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Longhi, M. Paula, Christine Trumpfheller, Juliana Idoyaga, et al. "Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant." Journal of Experimental Medicine 206, no. 7 (2009): 1589–602. http://dx.doi.org/10.1084/jem.20090247.

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Relative to several other toll-like receptor (TLR) agonists, we found polyinosinic:polycytidylic acid (poly IC) to be the most effective adjuvant for Th1 CD4+ T cell responses to a dendritic cell (DC)–targeted HIV gag protein vaccine in mice. To identify mechanisms for adjuvant action in the intact animal and the polyclonal T cell repertoire, we found poly IC to be the most effective inducer of type I interferon (IFN), which was produced by DEC-205+ DCs, monocytes, and stromal cells. Antibody blocking or deletion of type I IFN receptor showed that IFN was essential for DC maturation and develo
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Stevenson, H. C., G. A. Dekaban, P. J. Miller, C. Benyajati, and M. L. Pearson. "Analysis of human blood monocyte activation at the level of gene expression. Expression of alpha interferon genes during activation of human monocytes by poly IC/LC and muramyl dipeptide." Journal of Experimental Medicine 161, no. 3 (1985): 503–13. http://dx.doi.org/10.1084/jem.161.3.503.

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Human monocytes were activated to secrete alpha interferon (IFN-alpha) by poly IC/LC but not by other monocyte activators, such as muramyl dipeptide (MDP). In contrast, monocytes were activated to secrete fibroblast growth factor (FGF) release by MDP but not by poly IC/LC. The amount of total RNA present in unactivated and activated human monocytes was similar. Using two 32P-labeled cDNA probes (pLM001 and HuIFN-alpha 2) for human IFN-alpha genes in hybridization studies, we analyzed messenger RNA species from this gene family in activated human monocytes. After activation with poly IC/LC, two
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Caskey, Marina, François Lefebvre, Abdelali Filali-Mouhim, et al. "Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans." Journal of Experimental Medicine 208, no. 12 (2011): 2357–66. http://dx.doi.org/10.1084/jem.20111171.

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Adjuvants are critical for the success of vaccines. Agonists of microbial pattern recognition receptors (PRRs) are promising new adjuvant candidates. A mechanism through which adjuvants enhance immune responses is to stimulate innate immunity. We studied the innate immune response in humans to synthetic double-stranded RNA (polyinosinic:polycytidylic acid [poly IC] stabilized with poly-l-lysine [poly ICLC]), an agonist for toll-like receptor (TLR) 3, and the cytosolic RNA helicase MDA-5. Transcriptional analysis of blood samples from eight volunteers, after subcutaneous administration of poly
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Dissertations / Theses on the topic "Poly-ic"

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Wu, Jesse 1972. "Towards a poly-phon-ic environment." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/70865.

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Thesis (M. Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 1998.<br>Includes bibliographical references (p. 96-99).<br>This thesis explores an architectural/landscape environment where polyphonic metaphors are the means for exploration and investigation. Polyphonic, as described in musical definitions/ terms, is the style of composition in which two or more distinctly independent but organically related parts sound against one another. This combination produces associations within the piece that relate to various time lengths and musical instruments when particular musica
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Bulsara, Daksha. "The effects of Poly IC and human interferon #alpha# on rat hepatic CYP4A1 and CYP2E1." Thesis, University of Surrey, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334347.

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Gerarduzzi, Casimiro. "Poly IC induced antiviral responses of type I IFNs alter thymopoietic processes in mice : an apoptotic liaison." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97960.

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Type I IFNs modulate the onset of immune responses against viruses through the activation of numerous rapid signaling pathways. Although beneficial on specific infected cells, administered IFNs were shown to decrease thymic cellularity. Herein, we developed a murine model treated with polyinosinic:polycytidylic acid (Poly IC) to dissect the mechanisms and the role of in vivo produced IFNs on the thymus. Treatment induced thymic atrophy, while having no effect on the lymph nodes. However, under chronic conditions, we observed a complete thymic replenishment. These findings should be the result
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Ayari, Cherifa. "Optimisation de l'immunothérapie non spécifique du cancer superficiel de la vessie." Doctoral thesis, Université Laval, 2012. http://hdl.handle.net/20.500.11794/23499.

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Le cancer superficiel de la vessie (CSV) présente un taux élevé de récidive (60%). De ces récidives 10 à 15% progresseront vers un cancer infiltrant beaucoup plus dangereux. La résection transurétrale (RTU) des tumeurs superficielles est souvent suivie d’immunothérapie intravésicale par le BCG (Bacille-Calmette-Guérin) afin de prévenir la récidive et la progression ; cependant ce traitement échoue dans 40% des cas. De plus, la sévérité des effets secondaires empêche plusieurs patients de tolérer un traitement complet. La prédiction de la réponse au BCG et le développement de traitements altern
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Chung, Han-Hsuan, and 鍾瀚璿. "Effect of poly IC and ribavirin against enterovirus 71 infection in human neural cells." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/23258391204891462331.

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碩士<br>國立成功大學<br>醫學檢驗生物技術學系碩博士班<br>96<br>Enterovirus 71 (EV71) is the main causative agent of hand-foot-mouth disease, herpangina and has been associated with severe neurological disease like meningitis, encephalitis resulting in high mortalities. There is no effective antiviral drug could be used to cure the infection of EV71. In this study, we choose the interferon inducer poly IC and ribavirin to evaluate their effects on EV71 infection of human neuron cells. First, we selected two neural cell lines, SK-N-SH and U118MG to set up an in vitro EV71 infection model. We found EV71 infection in bo
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Hsieh, Dong-Ru, and 謝東儒. "A Study on Multi-Gate Poly-Si Junctionless and Junctionless Accumulation Mode FinFETs for Monolithic 3-D IC Applications." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/935yfu.

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博士<br>國立交通大學<br>電子物理系所<br>107<br>In this dissertation, we have successfully fabricated and demonstrated the n-type multi-gate poly-Si junctionless FinFETs (MG JL FinFETs) and the p-type multi-gate poly-Si junctionless accumulation mode FinFETs (MG JAM FinFETs) without the use of advanced lithography tools and ammonia-related plasma treatments by a low thermal-budget approach, namely, novel sidewall image transfer (SIT) technique. This approach has some advantages: 1) the channel thickness (Tch) can be controlled simply by the poly-Si layer thickness; 2) the shape of the fin channel can be cont
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Conference papers on the topic "Poly-ic"

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Zhang, Jianyu, Maofa Gong, Lanbing Li, Yanping Su, and Tao Liu. "Study on Poly Phase Multifunction Energy Metering IC." In 2013 Seventh International Conference on Image and Graphics (ICIG). IEEE, 2013. http://dx.doi.org/10.1109/icig.2013.154.

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Wolff, Martin, Sabine Bartel, Susanne Krauss-Etschmann, Heinz Fehrenbach, and Sebastian Reuter. "Poly (IC)-induced exacerbations in a murine smoke model affect DC populations." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa4459.

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Matsudai, Tomoko, Mamoru Terauchi, Makoto Yoshimi, Norio Yasuhara, Yukihiro Ushiku та Akio Nakagawa. "Evaluation of 0.3 μm Poly-Silicon CMOS Circuits for Intelligent Power IC Application". У 1997 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1997. http://dx.doi.org/10.7567/ssdm.1997.c-10-2.

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Qian, Zhongling, Christof Brillert, and Christian Burmer. "Lock-in Phase Mapping of Modulated Reflectance in Dynamically Operating Mixed-Signal IC Devices." In ISTFA 2012. ASM International, 2012. http://dx.doi.org/10.31399/asm.cp.istfa2012p0217.

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Abstract The lock-in phase mapping technique with modulated reflectance is introduced for the first time. With its help, the modulated reflectance mechanisms using thermal laser in operating FETs, particularly in the pinch off region, are clarified. The free carrier absorption mechanism dominates at a high modulation frequency, while thermo-reflectance mechanisms at a low modulation frequency. In the pinch-off region, thermo-reflectance mechanism cannot be neglected due to extremely low free carrier concentration. The modulated reflectance signal was unexpectedly observed at passive poly/oxide
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Ma, Shenglin, Yuliang Yi, Yaquan Tang, and Xiaomei Yu. "Design and Fabrication of Uncooled MEMS Capacitive FPA for IR Imaging." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70128.

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A new structure of MEMS Uncooled capacitive focal plane array (FPA) is presented and its thermo-mechanical behaviors are studied. A surface process with poly-silicon as a sacrificial layer was developed, and in which poly-silicon was dry etched by SF6 in an ICP system of STS. The etching rates of poly-silicon in lateral and vertical can reach 3.8 and 5.6μm/min after the optimization of the process. The process is simple and compatible with most of the IC processes.
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Hardaker, EL, MS Freeman, N. Dale, et al. "A Viral Mimetic, Poly(IC) Enhances the Inflammatory Response Elicited by Tobacco Smoke in Mice." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1503.

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Guo, B., L. Wen, P. Helin, et al. "Above-IC generic poly-SiGe thin film wafer level packaging and MEM device technology: Application to accelerometers." In 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2011. http://dx.doi.org/10.1109/memsys.2011.5734434.

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Hsieh, Don-Ru, Jer-Yi Lin, Po-Yi Kuo, and Tien-Sheng Chao. "Fabrication and characterization of Pi-gate poly-Si junctionless and inversion mode Fin-FETs for 3-D IC applications." In 2016 IEEE Silicon Nanoelectronics Workshop (SNW). IEEE, 2016. http://dx.doi.org/10.1109/snw.2016.7578007.

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Numata, Takanori, Jun Araya, Satoko Nojiri, et al. "Inhibition Of Poly-IC Induced Human Bronchial Epithelial Cell Apoptosis By Insulin-dependent PI3-Kinase/Akt And ERK Signaling Pathways." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4928.

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Wang, Mu-Chun, Zhen-Ying Hsieh, Shuang-Yuan Chen, and Heng-Sheng Huang. "Investigation of Contribution Ratio Between NBTI and HC Effects in PMOSFETs Under Deep-Submicron Process." In 2007 First International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2007. http://dx.doi.org/10.1115/mnc2007-21082.

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Quantifying the contribution of the hot carrier effect (HCE) and the negative bias temperature instability (NBTI) effect in PMOSFET device reliability is an urgent target, especially as the dual poly-gate implantation and the novel oxide growth recipe is derived. At this stage, the PMOS gate-oxide thickness is thinner than before, therefore, the implanted boron or BF2 is possible to penetrate from poly gate to surface channel. Furthermore, the implant source contains the plenty ionized hydrogen. This material is easily to be trapped in the gate oxide or bonded with the surface-channel silicon.
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