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Relevant bibliographies by topics / Poly-organic phenotypes

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Journal articles

Academic literature on the topic 'Poly-organic phenotypes'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Poly-organic phenotypes"

1

Dytiatkovskyi, V.O. "Personalized genotype markers of the atopic disorders phenotypes in children." Medicni perspektivi 28, no. 2 (2023): 99–105. https://doi.org/10.26641/2307-0404.2023.2.283346.

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The goal of the study was to elucidate the impact of the single nucleotide variants rs11466749 of the thymic stromal lymphopoietin gene, rs_7216389 of the orsomucoid-1-like protein 3 gene, and rs10052957 of the human nuclear glucocorticoid receptor subfamily 3, group C, member 1 gene on the development of the mono-organic phenotype “atopic eczema” or the poly-organic “atopic eczema + allergic rhinitis/allergic rhino-conjunctivitis”. We recruited 101 patients into the main and 105 into control groups aged from 3 to 18 years old. Patients of the main group suffered from a

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Dytiatkovskyi, V. O. "Personalized genotype markers of the atopic disorders phenotypes in children." Medicni perspektivi 28, no. 2 (2023): 99–105. http://dx.doi.org/10.26641/2307-0404.2023.2.283346.

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The goal of the study was to elucidate the impact of the single nucleotide variants rs11466749 of the thymic stromal lymphopoietin gene, rs_7216389 of the orsomucoid-1-like protein 3 gene, and rs10052957 of the human nuclear glucocorticoid receptor subfamily 3, group C, member 1 gene on the development of the mono-organic phenotype “atopic eczema” or the poly-organic “atopic eczema + allergic rhinitis/allergic rhino-conjunctivitis”. We recruited 101 patients into the main and 105 into control groups aged from 3 to 18 years old. Patients of the main group suffered from atopic eczema (58 childre

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Ahn, Johwan, Sarah Schroeder, Michael Beer, et al. "Ecology of the Microbial Community Removing Phosphate from Wastewater under Continuously Aerobic Conditions in a Sequencing Batch Reactor." Applied and Environmental Microbiology 73, no. 7 (2007): 2257–70. http://dx.doi.org/10.1128/aem.02080-06.

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ABSTRACT All activated sludge systems for removing phosphate microbiologically are configured so the biomass is cycled continuously through alternating anaerobic and aerobic zones. This paper describes a novel aerobic process capable of decreasing the amount of phosphate from 10 to 12 mg P liter−1 to less than 0.1 mg P liter−1 (when expressed as phosphorus) over an extended period from two wastewaters with low chemical oxygen demand. One wastewater was synthetic, and the other was a clarified effluent from a conventional activated sludge system. Unlike anaerobic/aerobic enhanced biological pho

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Fujisato, Toshia, and Yoshito Ikada. "New cartilage formation in vivo using chondrocytes seeded on poly(L‐lactide)." Macromolecular Symposia 103, no. 1 (1996): 73–83. http://dx.doi.org/10.1002/masy.19961030109.

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AbstractA chondrocyte‐poly(L‐lactide) (PLLA) composite was employed in an attempt to regenerate cartilage. Rat chondrocytes showed good proliferation on adherent polymer substrates like PLLA and type II collagen production under the in vitro condition. The collagen production became maximal on the 10th day after cultivation. From the in vivo study, seeded chondrocytes spread throughout the scaffold dispersively and a lot of small blood vessels were observed around the matrix when bFGF was coated on the PLLA scaffold. When the chondrocyte‐PLLA composite was transplanted into nude mouse, injecti

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Kim, Hyunbum, Ji Hoon Jeong, Mona Fendereski, et al. "Heparin-Mimicking Polymer-Based In Vitro Platform Recapitulates In Vivo Muscle Atrophy Phenotypes." International Journal of Molecular Sciences 22, no. 5 (2021): 2488. http://dx.doi.org/10.3390/ijms22052488.

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The cell–cell/cell–matrix interactions between myoblasts and their extracellular microenvironment have been shown to play a crucial role in the regulation of in vitro myogenic differentiation and in vivo skeletal muscle regeneration. In this study, by harnessing the heparin-mimicking polymer, poly(sodium-4-styrenesulfonate) (PSS), which has a negatively charged surface, we engineered an in vitro cell culture platform for the purpose of recapitulating in vivo muscle atrophy-like phenotypes. Our initial findings showed that heparin-mimicking moieties inhibited the fusion of mononucleated myoblas

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Rissel, Dagmar, and Edgar Peiter. "Poly(ADP-Ribose) Polymerases in Plants and Their Human Counterparts: Parallels and Peculiarities." International Journal of Molecular Sciences 20, no. 7 (2019): 1638. http://dx.doi.org/10.3390/ijms20071638.

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Poly(ADP-ribosyl)ation is a rapid and transient post-translational protein modification that was described first in mammalian cells. Activated by the sensing of DNA strand breaks, poly(ADP-ribose)polymerase1 (PARP1) transfers ADP-ribose units onto itself and other target proteins using NAD+ as a substrate. Subsequently, DNA damage responses and other cellular responses are initiated. In plants, poly(ADP-ribose) polymerases (PARPs) have also been implicated in responses to DNA damage. The Arabidopsis genome contains three canonical PARP genes, the nomenclature of which has been uncoordinated in

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Chamera, Katarzyna, Ewa Trojan, Katarzyna Kotarska, et al. "Role of Polyinosinic:Polycytidylic Acid-Induced Maternal Immune Activation and Subsequent Immune Challenge in the Behaviour and Microglial Cell Trajectory in Adult Offspring: A Study of the Neurodevelopmental Model of Schizophrenia." International Journal of Molecular Sciences 22, no. 4 (2021): 1558. http://dx.doi.org/10.3390/ijms22041558.

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Multiple lines of evidence support the pathogenic role of maternal immune activation (MIA) in the occurrence of the schizophrenia-like disturbances in offspring. While in the brain the homeostatic role of neuron-microglia protein systems is well documented, the participation of the CX3CL1-CX3CR1 and CD200-CD200R dyads in the adverse impact of MIA often goes under-recognized. Therefore, in the present study, we examined the effect of MIA induced by polyinosinic:polycytidylic acid (Poly I:C) on the CX3CL1-CX3CR1 and CD200-CD200R axes, microglial trajectory (MhcII, Cd40, iNos, Il-1β, Tnf-α, Il-6,

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Cho, Jang-Cheon, та Stephen J. Giovannoni. "Oceanicola granulosus gen. nov., sp. nov. and Oceanicola batsensis sp. nov., poly-β-hydroxybutyrate-producing marine bacteria in the order ‘Rhodobacterales’". International Journal of Systematic and Evolutionary Microbiology 54, № 4 (2004): 1129–36. http://dx.doi.org/10.1099/ijs.0.03015-0.

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Three Gram-negative, chemoheterotrophic, non-motile, rod-shaped bacterial strains that accumulate poly-β-hydroxybutyrate granules were isolated from the Bermuda Atlantic Time-series Study site by high-throughput culturing methods and characterized by polyphasic approaches. DNA–DNA hybridization, DNA G+C content and phylogenetic analyses based on 16S rRNA gene sequences divided the three isolates into two distinct genospecies that were clearly differentiated by fatty acid profiles, carbon source utilization patterns, antibiotic susceptibility and biochemical characteristics. The strains utilize

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Alghanem, Bandar, Rizwan Ali, Atef Nehdi, et al. "Proteomics Profiling of KAIMRC1 in Comparison to MDA-MB231 and MCF-7." International Journal of Molecular Sciences 21, no. 12 (2020): 4328. http://dx.doi.org/10.3390/ijms21124328.

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Proteomics characterization of KAIMRC1 cell line, a naturally immortalized breast cancer cells, is described in comparison to MCF-7 and MDA-MB-231 breast cancer cells. Quantitative proteomics analysis using the tandem mass tag (TMT)-labeled technique in conjunction with the phosphopeptide enrichment method was used to perform comparative profiling of proteins and phosphoproteins in the three cell lines. In total, 673 proteins and 33 Phosphoproteins were differentially expressed among these cell lines. These proteins are involved in several key cellular pathways that include DNA replication and

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Baum, Emily, Wenming Huang, Catherine Vincent-Delorme, Perrine Brunelle, Adam Antebi, and Hormos Salimi Dafsari. "Novel Genetic and Phenotypic Expansion in Ameliorated PUF60-Related Disorders." International Journal of Molecular Sciences 25, no. 4 (2024): 2053. http://dx.doi.org/10.3390/ijms25042053.

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Heterozygous variants in the Poly(U) Binding Splicing Factor 60kDa gene (PUF60) have been associated with Verheij syndrome, which has the key features of coloboma, short stature, skeletal abnormalities, developmental delay, palatal abnormalities, and congenital heart and kidney defects. Here, we report five novel patients from unrelated families with PUF60-related disorders exhibiting novel genetic and clinical findings with three truncating variants, one splice-site variant with likely reduced protein expression, and one missense variant. Protein modeling of the patient’s missense variant in

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