Academic literature on the topic 'Polychromatic erythrocyte'

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Journal articles on the topic "Polychromatic erythrocyte"

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Bharti, Shalini, and Arvind Kumar. "Genotoxic studies of Arsenic trioxide on polychromatic and normochromatic erythrocytes in bone marrow cells of (Mus musculus) swiss albino mice." PROCEEDINGS OF THE ZOOLOGICAL SOCIETY OF INDIA 24, no. 01 (2025): 77. https://doi.org/10.59467/pzsi.2025.24.77.

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The genotoxic potency of Arsenic trioxide in terms of induction of micronucleated polychromatic erythrocytes (MNPCE) and micronucleated Normochromatic erythrocyte (MNNCE) in bone marrow cells in Swiss albino mice (Mus musculus) has been investigated.For the research experiment, Adult Mus musculus of the same age group were selected for the research experiment and divided into three groups (Control, AA-1 & AA-2. After the completion of the treatment, slides wereprepared according to OECD guidelines. For the assessment of frequency of Mn in polychromatic or normochromatic erythrocytes 800 -
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Naranjo-Vázquez, Eduardo, María Guadalupe Sánchez-Parada, Belinda Claudia Gómez-Meda, et al. "Effect of High-Dose Topical Minoxidil on Erythrocyte Quality in SKH1 Hairless Mice." Animals 10, no. 4 (2020): 731. http://dx.doi.org/10.3390/ani10040731.

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SKH1 hairless mice are widely used in carcinogenesis and dermatology research due to their bare skin, as exposure to different agents is facilitated. Minoxidil is a cosmetic drug that is recognized as a mitogenic agent, and mitogens are suggested to have carcinogenic and mutagenic potential by inducing cell division and increasing the possibility of perpetuating DNA damage. Therefore, we hypothesized that the application of high doses of minoxidil to the skin of hairless mice would increase the number of micronucleated erythrocytes (MNEs) in peripheral blood. The objective of this study was to
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Astuti, Eha Renwi, Hutojo Djajakusuma, Indeswati Diyatri, and Nastiti Faradilla Ramadhani. "The effect of X-ray irradiation to the formation of polychromatic erythrocyte cell micronucleus in Wistar rats (Rattus norvegicus)." Dental Journal (Majalah Kedokteran Gigi) 54, no. 3 (2021): 128. http://dx.doi.org/10.20473/j.djmkg.v54.i3.p128-131.

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Background: Panoramic and cephalometric radiography is very important for diagnosis, treatment plan, and evaluation of orthodontic treatment results. Panoramic and cephalometric radiography are frequently performed at the same time, causing DNA damage and chromosome aberration. Purpose: This study aims to analyse the effect of X-ray exposure in panoramic and cephalometric radiography on micronuclei cell numbers. Methods: Laboratory-based analytical study with 60 healthy-male Wistar rats weighing 200–300 grams divided into 6 treatment groups (n=10). The control group: without radiographic expos
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Rasgele, Pinar Goc, Meral Kekecoglu, and Fulya Dilek Gokalp Muranli. "Induction of Micronuclei in Mice Bone Marrow Cells by Cobalt and Copper Chlorides." Archives of Environmental Protection 39, no. 1 (2013): 75–82. http://dx.doi.org/10.2478/aep-2013-0007.

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Abstract The aim of our research was to investigate the genotoxic effects of cobalt chloride and copper chloride in mouse bone marrow cells using the micronucleus (MN) assay. The three different concentrations of cobalt chloride (11.2, 22.5 and 45 mg kg-1) and copper chloride (1.17, 2.35 and 4.70 mg kg-1) were injected intraperitoneally to mice for 24 and 48 hours. It was observed that both of these heavy metals induced a significant increase in frequency of micronucleated polychromatic erythrocytes (MNPCE) at different concentrations in mice for 24 and 48 hours when compared with the control.
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Motto, Aku Enam, Povi Lawson-Evi, Aboudoulatif Diallo, and Kwashie Eklu-Gadegbeku. "Genotoxicity Assessment and Protective Effect of Anogeissus leiocarpus Roots against Cyclophosphamide-Induced DNA Damage In Vivo." Journal of Toxicology 2021 (November 8, 2021): 1–8. http://dx.doi.org/10.1155/2021/8020240.

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Background. Belonging to the family of Combretaceae, the roots of Anogeissus leiocarpus are traditionally used to treat diabetes, wounds, infections, pain, and gastrointestinal diseases. To our knowledge, no genotoxicity assessment of the plant was reported. Hence, this study was designed to evaluate the potential genotoxic and protective effects of extract of Anogeissus leiocarpus roots using the micronucleus test on mice bone marrow cells in vivo. Methods. Three different concentrations (250, 500, and 1000 mg·kg−1) of hydroalcoholic extract of roots of A. leiocarpus were administered daily f
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Jahan, Sanzida, Tasnim H. Beacon, Wayne Xu, and James R. Davie. "Atypical chromatin structure of immune-related genes expressed in chicken erythrocytes." Biochemistry and Cell Biology 98, no. 2 (2020): 171–77. http://dx.doi.org/10.1139/bcb-2019-0107.

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The major biological role of red blood cells is to carry oxygen to the tissues in the body. However, another role of the erythroid cell is to participate in the immune response. Mature erythrocytes from chickens express Toll-like receptors and several cytokines in response to stimulation of the immune system. We previously reported the application of a biochemical fractionation protocol to isolate highly enriched transcribed DNA from polychromatic erythrocytes from chickens. In conjunction with next-generation DNA, RNA sequencing, chromatin immunoprecipitation-DNA sequencing, and formaldehyde-
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Boriollo, M. F. G., T. A. Silva, M. F. Rodrigues-Netto, et al. "Reduction of doxorubicin-induced genotoxicity by Handroanthus impetiginosus in mouse bone marrow revealed by micronucleus assay." Brazilian Journal of Biology 78, no. 1 (2017): 1–12. http://dx.doi.org/10.1590/1519-6984.18515.

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Abstract Handroanthus impetiginosus has long been used in traditional medicine and various studies have determined the presence of bioactive chemical compounds and potential phytotherapeutics. In this study, the genotoxicity of the lyophilized tincture of H. impetiginosus bark (THI) was evaluated in mouse bone marrow using micronucleus assays. The interaction between THI and genotoxic effects induced by the chemotherapeutic agent, doxorubicin (DXR), was also analyzed. Experimental groups were evaluated 24 to 48 h after treatment with N-nitroso-N-ethylurea (NEU; 50 mg/kg), DXR (5 mg/kg), sodium
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Mojidra, BN, K. Archana, AK Gautam, Y. Verma, BC Lakkad, and Sunil Kumar. "Evaluation of genotoxicity of pan masala employing chromosomal aberration and micronucleus assay in bone marrow cells of the mice." Toxicology and Industrial Health 25, no. 7 (2009): 467–71. http://dx.doi.org/10.1177/0748233709345939.

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Pan masala is commonly consumed in south-east Asian and other oriental countries as an alternate of tobacco chewing and smoking. Genotoxic potential of pan masala (pan masala plain and pan masala with tobacco known as gutkha) was evaluated employing chromosome aberration (CA) and micronucleus (MN) assay in vivo. Animals were exposed to three different doses (0.5%, 1.5% and 3%) of pan masala plain (PMP) and gutkha (PMT) through feed for a period of 6 months and micronucleus and chromosomal aberrations were studied in the bone marrow cells. Induction of mean micronuclei in polychromatic erythroc
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Jagetia, G. C., та P. Venkatesh. "Inhibition of radiation-induced clastogenicity by Aegle marmelos (L.) Correa in mice bone marrow exposed to different doses of γ-radiation". Human & Experimental Toxicology 26, № 2 (2007): 111–24. http://dx.doi.org/10.1177/0960327107071867.

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The frequency of micronucleated polychromatic (MPCE), normochromatic erythrocytes (MNCE), and polychromatic/normochromatic erythrocyte ratio (PCE/NCE), was studied in the bone marrow of mice orally administered with 0, 200, 225, 250, 275 and 300 mg/kg body weight of hydroalcoholic leaf extract of Aegle marmelos (AME). Treatment of mice with AME, once daily for 5 consecutive days, before exposure to 2 Gy resulted in a significant decline in the frequency of MPCE when compared to the non-drug-treated irradiated control. The greatest reduction in MPCE was observed for 250 mg/kg body weight AME, a
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Tugbobo Oladimeji Samuel, Idowu Kayode Solomon, and Apata Dasola Airat. "Effect of dimercaptosuccinic acid against lead-induced clastogenicity and enzyme activity in mice in-vivo." GSC Biological and Pharmaceutical Sciences 26, no. 1 (2024): 167–70. http://dx.doi.org/10.30574/gscbps.2024.26.1.0522.

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Indiscriminate exposure of humans to heavy metal contamination via occupation and enviro nmental pollution has been reported with its attendant health burdens including genetic mutation and cancer. This study examined effect of dimercaptosuccinic acid (DMSA) a metal chelator against lead-induced mutagenicity in mice and resultant effect on proper formation of erythrocyte cells. Lead acetate (2.5 mg/kg b.wt) and DMSA (25 mg/kg b.wt) were fed to the mice via oral gavage for 14 consecutive days. Clastogenic effects were observed in the bone marrow cells using micronucleus assay while activity of
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Book chapters on the topic "Polychromatic erythrocyte"

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Osipov Andreyan N. "Late and Low Dose Radiation Effects in Mammals as a Consequence of the Accidental Radionuclide Release to the Environment." In NATO Science for Peace and Security Series - E: Human and Societal Dynamics. IOS Press, 2010. https://doi.org/10.3233/978-1-60750-645-4-269.

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The results of the experiments modelling a low dose-rate irradiation at radioactive contaminated territories (dose-rate of 61-62.5 cGy/year) showed that gamma-rays irradiation results in statistically significant changes in the DNA strand breaks level, apoptotic cells frequency, and reactive oxygen species production rate in mouse blood system cells starting of doses above 14-20 cGy. No significant increase in the cytogenetic disturbance frequencies was found in mice at doses up to ˜ 60 cGy. The results of biomonitoring studies of bank voles populations showed that voles captured from the radionuclide contaminated territories (dose-rate of 0.012-0.72 mGy/day), as a rule, were characterised by normal hematological and pathology-morphological indices. No significant increase in the DNA breaks level was found in spleen cells and peripheral blood leukocytes or in the percent of bone marrow polychromatic erythrocytes with micronuclei. The data obtained strongly support the non-linear threshold hypothesis of low dose-rate ionizing radiation genotoxic action.
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Conference papers on the topic "Polychromatic erythrocyte"

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"Effect of Mirazid on the Micronuclei Polychromatic Erythrocyte Cells (MNPCEs) In the Bone Marrow Cells of Schistosoma Infected and Non Infected Mice." In 5th International Conference on Food, Agricultural and Biological Sciences. Universal Researchers (UAE), 2016. http://dx.doi.org/10.17758/uruae.ae1216239.

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Reports on the topic "Polychromatic erythrocyte"

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Shore, Karen, and Paul Kirby. In Vivo Test for Chemical Induction of Micronucleated Polychromatic Erythrocytes in Mouse Bone Marrow Cells, Test Article: Ethylenediamine Dinitrate (EDDN). Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada518233.

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