Academic literature on the topic 'Polycystic ovarian syndrome'

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Journal articles on the topic "Polycystic ovarian syndrome"

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Mathew, Niky. "PCOS (Polycystic Ovarian Syndrome)." International Journal of Science and Research (IJSR) 12, no. 8 (2023): 367–70. http://dx.doi.org/10.21275/sr23801144740.

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Gursu, Turkan, Halime Cevik, Güldeniz Aksan Desteli, Birnur Yilmaz, Tevfik Berk Bildaci, and Alper Eraslan. "Diagnostic value of shear wave velocity in polycystic ovarian syndrome." Journal of Ultrasonography 21, no. 87 (2021): 277–81. http://dx.doi.org/10.15557/jou.2021.0047.

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Aim: In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. Material and methods: The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycy
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VN, Aanandhi. "Contemplation on Polycystic Ovarian Syndrome." International Journal of Preventive, Curative & Community Medicine 08, no. 3&4 (2022): 17–22. http://dx.doi.org/10.24321/2454.325x.202208.

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Psilopatis, Iason, Christos Damaskos, Nikolaos Garmpis, et al. "Ovarian Torsion in Polycystic Ovary Syndrome: A Potential Threat?" Biomedicines 11, no. 9 (2023): 2503. http://dx.doi.org/10.3390/biomedicines11092503.

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Polycystic ovary syndrome (PCOS) constitutes the most prevalent endocrine disorder in women of reproductive age worldwide. Given the increased risk of ovarian torsion in the presence of large ovarian cysts, polycystic ovarian syndrome could be regarded as one of the most significant risk factors for ovarian and/or adnexal torsion in cases of significantly enlarged ovaries. The aim of the present review is to investigate, for the first time, the association between polycystic ovarian syndrome and ovarian torsion. We performed a review of the literature using the MEDLINE and LIVIVO databases in
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Kumari, Rajni, Ranjan Kumar Singh, and Ajay Garg. "“Herbal plants used in the treatment of PCOS-A Comprehensive review”." International Journal of Pharma Professional’s Research (IJPPR) 15, no. 1 (2024): 57–71. http://dx.doi.org/10.48165/ijppronline.10.48165/ijppronline.2024.15105.

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Polycystic ovarian syndrome is a common endocrine metabolic illness marked by polycystic ovaries, persistent anovulation, and hyperandrogenism, resulting in symptoms of monthly irregularity, infertility, and hirsutism. Various medicinal therapies for polycystic ovarian syndrome have been offered. However, the potential adverse effects of long-term therapies, as well as their limited effectiveness, have made complementary and alternative treatments a viable choice. According to recent estimates, the usage of complementary therapies is on the rise. Various plants like Saraca asoka, Moringa olife
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Malik, Mariam A., and Sura F. Alsaffar. "Assessment of Intestinal Hormones Cholecystokinin and Peptide YY in Iraqi Women with Polycystic Ovarian Syndrome." Journal of the Faculty of Medicine Baghdad 67, no. 1 (2025): 50–55. https://doi.org/10.32007/jfacmedbaghdad2441.

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Background: Among the most prevalent hormonal, reproductive and metabolic issues impacting women is polycystic ovarian syndrome. Also, insulin resistance raises the chance of developing chronic illnesses in women with polycystic ovarian syndrome, including diabetes mellitus, cardiovascular disease, metabolic syndrome, and potentially endometrial and breast malignancies.Objectives: Measurement of two intestinal hormones (cholecystokinin, peptide YY), luteinising hormone, follicle-stimulating hormone, and Prolactin. Waist and wrist circumference were measured in centimetersMethods: A sample of p
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Jeengar, Pooja, and Madhubala Chauhan. "Association of metabolic syndrome in polycystic ovarian syndrome." New Indian Journal of OBGYN 3, no. 2 (2017): 90–94. http://dx.doi.org/10.21276/obgyn.2017.3.2.5.

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Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "A Pathophysiology, Diagnosis, Differential Diagnosis and Treatment of Poly Cystic Ovarian Disease." Journal of Mental health, Psychiatric and Psychosocial Nursing 3, no. 1 (2024): 14–24. https://doi.org/10.5281/zenodo.14557185.

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<em>Among women of reproductive age, polycystic ovarian syndrome (PCOS) is the most prevalent hormonal condition. Polycystic ovaries, hyperandrogenism, and irregular menstrual cycles are some of its characteristics. The assessment and management of polycystic ovarian syndrome are explained in this activity, which also briefly goes over the function of the interprofessional team in treating patients with this illness.</em> &nbsp; <strong><em>Objectives</em></strong> &middot;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <em>Narrate</em><em> the epidemiology of polycystic ovarian syndrome.</em
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Boqun, Xu, Dai Xiaonan, Cui YuGui, et al. "Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome." International Journal of Endocrinology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/367956.

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Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries.Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and surgical treatment with the signed consent form. The cellular localization of SET protein was observed b
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Muhammad, Bakhtyar Kamal. "Characteristics and Risk Factors for Polycystic Ovarian Syndrome Among Females." Kurdistan Journal of Applied Research 5, no. 1 (2020): 200–209. http://dx.doi.org/10.24017/science.2020.1.14.

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Polycystic ovary syndrome (PCOS) is a major endocrinal syndrome may affect the female at adult ages. In polycystic ovary, the ovarian seen that are enlarged and the investigation may base on ultra-sonographic detection. Polycystic ovarian syndrome always represents a spectrum of syndrome rather than the diseases. Also clinically presented by polycystic on ovarian and generally demonstrated by reversible. 104 female patients were examined, 18 (17.3%) of females were diagnosed with polycystic ovarian syndrome. The mean age was 24.62 ± 7.32 years (ranged from 15 month to 50 years-old). 17 (94.4%)
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Dissertations / Theses on the topic "Polycystic ovarian syndrome"

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Alzanati, Nadia. "Polycystic ovarian syndrome and adipose tissue : contribution of peripheral androgen synthesis to hyperandrogenism in polycystic ovarian syndrome." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/39390/.

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Background: Polycystic ovarian syndrome (PCOS) is the most common endocrine, reproductive, metabolic and psychological disorder in women of childbearing age, affecting 6-10% of premenopausal women. Hyperandrogenism is the most important biochemical feature of the syndrome, which is responsible for the clinical features of PCOS, and is frequently associated with metabolic disturbance, such as insulin resistance, dyslipidaemia, glucose intolerance and hypertension, regardless of the presence of obesity. In several studies, attention has focused on androgen as the main factor for development of m
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Hudecova, Miriam. "Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-123248.

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Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. The overall risk of developing type 2 diabetes and impaired glucose tolerance (IGT) is three- to sevenfold higher in PCOS women, and the onset of glucose intolerance seems to occur at an earlier age than in healthy controls. Women with PCOS also have several risk factors for cardiovascular dis
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Marsden, Philippa Jane. "Insulin action and ovarian function in polycystic ovary syndrome." Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313272.

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Kilpatrick, Kaylon Ann. "Starvation induces Polycystic Ovarian Syndrome (PCOS) like symptoms in Drosophila melanogaster." Thesis, Mississippi College, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10128977.

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<p> Polycystic Ovarian Syndrome (PCOS) is a metabolic and endocrine disorder that is the most common cause of infertility. PCOS can manifest itself as a long and short term disability and is characterized by insulin resistance (IR), hyperandrogenism, anovulation, hyperinsulinaemia and polycystic ovaries. Our lack of understanding of this disorder and its long term effects has complicated the treatment of the disorder; yet, it is clear that PCOS involves the intricate interaction between genetics, environments and behaviors. To study this disease, scientists have used various animal models. Sin
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Desjardins, G. Clarissa (Gina Clarissa). "Role of the hypothalamic opioid system in estradiol-induced polycystic ovarian syndrome." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=41015.

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The intrahypothalamic distribution of mu, delta and kappa opioid receptor types was examined by in vitro radioautography using the opioid ligands $ sp{125}$I-FK-33 824, $ sp{125}$I-DTLET and $ sp{125}$I-DPDYN, respectively as selective markers. The density and distribution of these receptors in the hypothalamus of normal rats was then compared to that of rats injected with estradiol valerate in order to verify the location of the described increase in $ sp3$H-naloxone binding and to identify the specific opioid receptor type involved. Analysis of opioid receptor changes following long-term exp
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Wang, Qi. "Chemerin and Prohibitin in the Regulation of Ovarian Follicular Development and their Potential Involvement in Polycystic Ovarian Syndrome." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24098.

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Follicular growth and maturation are tightly regulated processes, which involve the participation of endocrine, autocrineparacrine factors and intracellular molecules. Due to the numerous research efforts, a large number of regulators and their mechanisms of regulation of follicular growth and differentiation have been established. Although the abnormal expression and activities of some of these regulators are believed to be associated with ovarian dysfunction diseases, such as polycystic ovarian syndrome (PCOS), the etiology and pathogenesis of this syndrome are not completely understood. In
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Sprung, Victoria Spencer. "The impact of obesity and fitness on endothelial function in polycystic ovarian syndrome." Thesis, Liverpool John Moores University, 2012. http://researchonline.ljmu.ac.uk/6119/.

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Polycystic ovarian syndrome (PCOS) is a highly prevalent heterogeneous syndrome associated with abdominal obesity, insulin resistance and the metabolic syndrome. This clustering of risk factors could translate into an adverse cardiovascular disease (CVD) risk profile. Endothelial dysfunction, an early barometer of CVD, has been exhibited by women with PCOS; however, it remains unclear whether endothelial dysfunction is independent of CVD risk factors in this population. Exercise training has been found to enhance conduit artery and cutaneous microvessel endothelial function in various populati
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El, Mahdi E. "Studies to investigate a possible association between Polycystic Ovary Syndrome and Epithelial Ovarian Cancer." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1397057/.

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Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders, affecting 5 % to 10 % of women of reproductive age. The Syndrome is associated with Type II diabetes and endometrial carcinoma but an association with epithelial ovarian cancer has also been suggested. The studies described in this thesis were designed to investigate this association at population, cellular and molecular levels. In the first study, a cross sectional questionnaire survey was conducted of 121 women aged between the ages of 20 and 40, with or without PCOS. Analysis of the replies from 52 women with
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Al-Mizyen, Ebtisam S. S. "Unilateral versus bilateral laparoscopic ovarian diathermy in the management of infertile women with clomiphene citrate resistant polycystic ovarian syndrome." Thesis, Queen Mary, University of London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538365.

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Konecki, Angela. "A Retrospective Analysis of the Effect Weight Loss and Metformin use in Polycystic Ovarian Syndrome." The University of Arizona, 2006. http://hdl.handle.net/10150/624469.

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Class of 2006 Abstract<br>Objectives: To determine if Polycystic Ovarian Syndrome (PCOS) patients treated with lifestyle changes and metformin resulted in ovulation after six months of treatment. Methods: A retrospective chart review of initial patient visits at an infertility clinic were obtained. Patients that were given a diagnosis of PCOS were further reviewed for age at initial diagnosis, weight, height, ovarian cysts, lifestyle recommendations (diet, exercise, and vitamin use), metformin recommendations and usage, and if ovulation occurred after six months of treatment. Results: A tota
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Books on the topic "Polycystic ovarian syndrome"

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Diamanti-Kandarakis, Evanthia, John E. Nestler, Dimitrios Panidis, and Renato Pasquali, eds. Insulin Resistance and Polycystic Ovarian Syndrome. Humana Press, 2007. http://dx.doi.org/10.1007/978-1-59745-310-3.

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Hajam, Younis Ahmad, Rajesh Kumar, D. R. Thakur, and Seema Rai. Herbal Medicine Applications for Polycystic Ovarian Syndrome. CRC Press, 2023. http://dx.doi.org/10.1201/9781003344728.

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Payal, A. P. Her-sutism: A comic about polycystic ovarian syndrome. A.P. Payal, 2018.

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Evanthia, Diamanti-Kandarkis, ed. Insulin resistance and polycystic ovarian syndrome: Pathogenesis, evaluation, and treatment. Humana Press, 2007.

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Evanthia, Diamanti-Kandarkis, ed. Insulin resistance and polycystic ovarian syndrome: Pathogenesis, evaluation, and treatment. Humana Press, 2007.

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Samra, J. S. Endocrine and metabolic studies in patients with polycystic ovarian syndrome. University of Birmingham, 1992.

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Futterweit, Walter. A patient's guide to PCOS: Understanding and reversing polycystic ovarian syndrome. Edited by Ryan George. Henry Holt, 2006.

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George, Tolis, Bringer Jacques, and Chrousos George P, eds. Intraovarian regulators and polycystic ovarian syndrome: Recent progress on clinical and therapeutic aspects. New York Academy of Sciences, 1993.

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Parker, James N., and Philip M. Parker. Polycystic ovarian syndrome: A medical dictionary, bibliography, and annotated research guide to Internet references. ICON Health, 2004.

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Humphrey, Katie. Freedom from PCOS: 3 proven steps to naturally overcome polycystic ovarian syndrome and insulin resistance. K. Humphrey, 2010.

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Book chapters on the topic "Polycystic ovarian syndrome"

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Annamalai, Aniyizhai. "Polycystic Ovarian Syndrome." In Medical Management of Psychotropic Side Effects. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-51026-2_46.

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Hernandez, M. Isabel, and Verónica Mericq. "Polycystic Ovarian Syndrome." In Brook's Clinical Pediatric Endocrinology. Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444316728.ch21.

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De Nicola, Ana Luisa Alencar, and Harley De Nicola. "Polycystic Ovarian Syndrome." In Atlas of Imaging in Infertility. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-13893-0_2.

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Pal, Lubna, and Shefali Pathy. "Polycystic ovarian syndrome." In Evidence-based Obstetrics and Gynecology. John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781119072980.ch12.

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Al-Salem, Ahmed H. "Polycystic Ovarian Syndrome." In Pediatric Gynecology. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-49984-6_14.

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Wierman, Margaret E. "Polycystic Ovarian Syndrome." In 2016 Meet-The-Professor: Endocrine Case Management. The Endocrine Society, 2016. http://dx.doi.org/10.1210/mtp5.9781943550043.ch57.

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Christou, Maria A., Gesthimani Mintziori, Dimitrios G. Goulis, and Basil C. Tarlatzis. "Polycystic Ovarian Syndrome." In Amenorrhea. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-22378-5_8.

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Shoupe, Donna. "Polycystic Ovarian Syndrome." In Management of Common Problems in Obstetrics and Gynecology. Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444323030.ch93.

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Shukla, Alpana, and Lindsay Mandel. "Polycystic Ovarian Syndrome." In Obesity Management. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-01039-3_4.

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Dokras, Anuja, and William I. Sivitz. "Polycystic Ovarian Syndrome." In Early Diagnosis and Treatment of Endocrine Disorders. Humana Press, 2003. https://doi.org/10.1007/978-1-59259-378-1_9.

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Conference papers on the topic "Polycystic ovarian syndrome"

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Tasnim, Mayesha, Sejuty Das, Shafee Shadman Tonoy, and T. M. Shahriar Sazzad. "Follicle Detection in Polycystic Ovary Syndrome Using Ovarian Ultrasound Images." In 2025 International Conference on Electrical, Computer and Communication Engineering (ECCE). IEEE, 2025. https://doi.org/10.1109/ecce64574.2025.11013906.

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Thorat, Snehal, Nihar Ranjan, Vaishnavi Gangal, Tejal Jogdand, Sahas Kulat, and S. P. Rao Borde. "Identification of Polycystic Ovarian Syndrome through Clinical Metrics and Ultrasonographic Imaging Analysis." In 2024 IEEE International Conference on Contemporary Computing and Communications (InC4). IEEE, 2024. http://dx.doi.org/10.1109/inc460750.2024.10649348.

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Prathibanandhi, J., and G. S. Annie Grace Vimala. "Diagnosis of Polycystic Ovarian Syndrome with the Implementation of Deep Learning Models." In 2024 Third International Conference on Electrical, Electronics, Information and Communication Technologies (ICEEICT). IEEE, 2024. http://dx.doi.org/10.1109/iceeict61591.2024.10718482.

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Olaolu, Tomilola D., Damilare E. Rotimi, Toluwaloju J. Okuntola, Charles Nwonuma, and Ayotunde P. Olaolu. "Effects of Agnus castus aqueous leaf extract on letrozole-induced polycystic ovarian syndrome in rats." In 2024 International Conference on Science, Engineering and Business for Driving Sustainable Development Goals (SEB4SDG). IEEE, 2024. http://dx.doi.org/10.1109/seb4sdg60871.2024.10630393.

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Cruze, Francis Rudra D., Amina Khatun, Md Faruk Hosen, Mohammad Sarwar Hossain Mollah, Md Nasimul Kader, and Muhammad Shahin Uddin. "Leveraging Machine Learning to Uncover Molecular Pathways and Candidate Drugs in Ovarian Cancer and Polycystic Ovary Syndrome." In 2025 International Conference on Electrical, Computer and Communication Engineering (ECCE). IEEE, 2025. https://doi.org/10.1109/ecce64574.2025.11013839.

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Kanase, Saraswati. "To Compare the Effectivenes of Presribed Low Carbohydrate Diet versus Balanced Diet in the Management of Polycystic Ovarian Syndrome." In World Conference on Gynecology, Obstetrics, and Pediatrics. Eurasia Conferences, 2025. https://doi.org/10.62422/978-81-981865-0-8-003.

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INTRODUCTION : Polycystic ovarian syndrome is a group of conditions with – menstrual irregularities, anovulatory cycles, hyperandrogenism and polycystic ovarian morphology. The possible factors include – Genetic factor and epigenetic factors Polycystic ovary syndrome (pcos) mainly affects women of reproductive age. It affects 8% to 13% of women of reproductive age. The prevalence of pcos in india is 3.7 to 22.5%. Most influential factor in insulin levels is dietary carbohydrates specially processed carbs. The dietary carbohydrates is most important and easily modifiable factor in patients with
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Genola Moore, Moesha Danielle, Kevin Baboolal, and Patrick Hosein. "On the Prediction of Polycystic Ovarian Syndrome." In 2023 IEEE International Conference on Technology Management, Operations and Decisions (ICTMOD). IEEE, 2023. http://dx.doi.org/10.1109/ictmod59086.2023.10438162.

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Madhumitha, J., M. Kalaiyarasi, and S. Sakthiya Ram. "Automated Polycystic Ovarian Syndrome Identification with Follicle Recognition." In 2021 3rd International Conference on Signal Processing and Communication (ICPSC). IEEE, 2021. http://dx.doi.org/10.1109/icspc51351.2021.9451720.

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Tanwar, Akanksha, Anima Jain, and Anamika Chauhan. "Accessible Polycystic Ovarian Syndrome Diagnosis Using Machine Learning." In 2022 3rd International Conference for Emerging Technology (INCET). IEEE, 2022. http://dx.doi.org/10.1109/incet54531.2022.9824049.

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Mehrotra, Palak, Chandan Chakraborty, Biswanath Ghoshdastidar, Sudarshan Ghoshdastidar, and Kakoli Ghoshdastidar. "Automated ovarian follicle recognition for Polycystic Ovary Syndrome." In 2011 IEEE International Conference on Image Information Processing (ICIIP). IEEE, 2011. http://dx.doi.org/10.1109/iciip.2011.6108968.

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Reports on the topic "Polycystic ovarian syndrome"

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Liang, Xingyan, Yu Su, Chunli Lu, and Hongxia Ma. Chinese herbal medicine combined with acupuncture for women with polycystic ovarian syndrome. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.8.0048.

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Yang, Liu, FX Liang, Y. Yuan, et al. Efficacy of progestin-primed ovarian stimulation (PPOS) in patients with polycystic ovary syndrome during IVF/ICSI treatments: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0059.

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Review question / Objective: This systematic review aims to evaluate the efficacy of progestin-primed ovarian stimulation (PPOS) on reproductive outcomes in patients with polycystic ovary syndrome (PCOS) undergoing assisted reproductive techniques. Condition being studied: PCOS is a common endocrine disorder that can cause infertility in women of childbearing age. The PPOS protocol, which involves oral progestins with gonadotropin (Gn), has been shown to be effective and safe in treating patients with PCOS. However, the question of whether PPOS provides a significant benefit over conventional
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zeng, meifang, and Hailing Jiang. Effects of different endometrial preparation protocols on pregnancy outcomes in women with polycystic ovarian syndrome undergoing frozen embryo transfer:A network meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. http://dx.doi.org/10.37766/inplasy2024.5.0001.

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Feng, Jia, Shan Duan, and Waqas Ahmed. Comparison of combined clomiphene and letrozole versus only letrozole for ovulation induction in women with polycystic ovarian syndrome: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.8.0109.

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Glintborg, Dorte, Naja Due Kolster, Pernille Ravn, and Marianne Skovsager Andersen. Prospective risk of type 2 diabetes in normal weight women with polycystic ovary syndrome. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.6.0070.

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Review question / Objective: To investigate the risk for type 2 diabetes (T2D) in normal weight women with PCOS. The following PECOs (Population, Exposure, Comparator and Outcome) were included: Population: Pre- and postmenopausal women. Exposure: PCOS Comparator: Healthy control or background population. Outcome: T2D. Condition being studied: Polycystic ovary syndrome (PCOS) is a common endocrine disorder of reproductive-aged women with a prevalence of 15–20%. Polycystic ovary syndrome (PCOS) is most often defined according to the Rotterdam criteria, which include irregular ovulation, biochem
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