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1

Mathew, Niky. "PCOS (Polycystic Ovarian Syndrome)." International Journal of Science and Research (IJSR) 12, no. 8 (2023): 367–70. http://dx.doi.org/10.21275/sr23801144740.

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2

Gursu, Turkan, Halime Cevik, Güldeniz Aksan Desteli, Birnur Yilmaz, Tevfik Berk Bildaci, and Alper Eraslan. "Diagnostic value of shear wave velocity in polycystic ovarian syndrome." Journal of Ultrasonography 21, no. 87 (2021): 277–81. http://dx.doi.org/10.15557/jou.2021.0047.

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Aim: In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. Material and methods: The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycystic ovarian syndrome patients and 32 patients without a diagnosis of polycystic ovarian syndrome. Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, prolactin, antimullerian hormone levels, and menstrual patterns with clinical hyperandrogenism were evaluated. On the menstrual cycle days 2–4, by performing a transvaginal ultrasound scan, the ovarian volumes and antral follicle counts in both ovaries were recorded for each woman. The ultrasound system was converted into the elastography mode, and acoustic radiation force impulse imaging was performed. Shear wave velocity (m/sec) was measured at least 5 times for each ovary, and the mean value was calculated for each polycystic ovarian syndrome and non-polycystic ovarian syndrome woman. Results: Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, and prolactin levels were similar between the groups (p >0,05). Antimullerian hormone levels, antral follicle counts, and mean ovarian volumes were statistically different between the groups (p <0,05). Mean shear wave velocity values for both ovaries were 2.12 ± 0.82 (0.78–4.9) m/sec in the polycystic ovarian syndrome group, and 1.18 ± 0.41 (0.77–2.0) m/sec in the non-polycystic ovarian syndrome group, which was statistically significantly different (p = 0.016). Conclusion: In our study, we found significantly higher shear wave velocity levels in polycystic ovarian syndrome women than non-polycystic ovarian syndrome women, which indicates an impact of the condition on shear wave velocity. The increased acoustic frequencies cause a decreased response in time to transition, and motion becomes out of phase; in other words, scattered waves are faster in stiffer ovaries. Our results are thus compatible with the pathophysiology of the disease. Shear wave velocity is a beneficial tool for evaluating ovarian elasticity in polycystic ovarian syndrome patients in whom the levels are found to be significantly higher than non-polycystic ovarian syndrome women. In light of these findings, shear wave velocity is expected to be slower than polycystic ovarian syndrome levels in ovulatory women.
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VN, Aanandhi. "Contemplation on Polycystic Ovarian Syndrome." International Journal of Preventive, Curative & Community Medicine 08, no. 3&4 (2022): 17–22. http://dx.doi.org/10.24321/2454.325x.202208.

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4

Psilopatis, Iason, Christos Damaskos, Nikolaos Garmpis, et al. "Ovarian Torsion in Polycystic Ovary Syndrome: A Potential Threat?" Biomedicines 11, no. 9 (2023): 2503. http://dx.doi.org/10.3390/biomedicines11092503.

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Polycystic ovary syndrome (PCOS) constitutes the most prevalent endocrine disorder in women of reproductive age worldwide. Given the increased risk of ovarian torsion in the presence of large ovarian cysts, polycystic ovarian syndrome could be regarded as one of the most significant risk factors for ovarian and/or adnexal torsion in cases of significantly enlarged ovaries. The aim of the present review is to investigate, for the first time, the association between polycystic ovarian syndrome and ovarian torsion. We performed a review of the literature using the MEDLINE and LIVIVO databases in order to find relevant studies. By using the search terms “polycystic ovarian syndrome” and “ovarian torsion”, we were able to identify 14 studies published between 1995 and 2019. The present work constitutes the most up-to-date, comprehensive literature review focusing on the risk of ovarian/adnexal torsion in patients with polycystic ovaries. Ovarian/adnexal torsion seems to be a feared complication in patients with polycystic ovary syndrome. Acute lower abdominal pain in patients with known polycystic ovaries represents the most common symptom, while diagnostic assessment almost always incorporates transvaginal ultrasound and computer tomography or magnetic resonance tomography scans. In case of suspected torsion, emergency laparoscopy with ovarian or adnexal detorsion seems to be the standard therapeutic approach with a view to restitute the interrupted blood supply. In cases of repeated ovarian/adnexal torsions, ovariopexy or ovariectomy/adnexectomy had to be discussed with the patient in the context of risk recurrence minimization.
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Kumari, Rajni, Ranjan Kumar Singh, and Ajay Garg. "“Herbal plants used in the treatment of PCOS-A Comprehensive review”." International Journal of Pharma Professional’s Research (IJPPR) 15, no. 1 (2024): 57–71. http://dx.doi.org/10.48165/ijppronline.10.48165/ijppronline.2024.15105.

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Polycystic ovarian syndrome is a common endocrine metabolic illness marked by polycystic ovaries, persistent anovulation, and hyperandrogenism, resulting in symptoms of monthly irregularity, infertility, and hirsutism. Various medicinal therapies for polycystic ovarian syndrome have been offered. However, the potential adverse effects of long-term therapies, as well as their limited effectiveness, have made complementary and alternative treatments a viable choice. According to recent estimates, the usage of complementary therapies is on the rise. Various plants like Saraca asoka, Moringa olifera, Asparagus racemosus, Cimicifuga racemose etc., proved active in the treatment of polycystic ovarian syndrome. In this review, attempts have been made to summarize the important medicinal plants which are used in the treatment or prevention of polycystic ovarian syndrome. This article will be helpful for the upcoming researchers in their investigation of Polycystic ovarian syndrome.
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6

Malik, Mariam A., and Sura F. Alsaffar. "Assessment of Intestinal Hormones Cholecystokinin and Peptide YY in Iraqi Women with Polycystic Ovarian Syndrome." Journal of the Faculty of Medicine Baghdad 67, no. 1 (2025): 50–55. https://doi.org/10.32007/jfacmedbaghdad2441.

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Background: Among the most prevalent hormonal, reproductive and metabolic issues impacting women is polycystic ovarian syndrome. Also, insulin resistance raises the chance of developing chronic illnesses in women with polycystic ovarian syndrome, including diabetes mellitus, cardiovascular disease, metabolic syndrome, and potentially endometrial and breast malignancies.Objectives: Measurement of two intestinal hormones (cholecystokinin, peptide YY), luteinising hormone, follicle-stimulating hormone, and Prolactin. Waist and wrist circumference were measured in centimetersMethods: A sample of polycystic ovarian syndrome women who were referred to the Medical City of Baghdad hospital for management of their infertility were recruited in the current study. Sixty polycystic ovarian syndrome patients were split into two groups based on Body Mass Index: thirty obese polycystic ovarian syndrome women and thirty overweight polycystic ovarian syndrome women. In addition, thirty healthy control women were added as a third group, whose average age was between 20 and 35 years. Polycystic ovarian syndrome in women was diagnosed using two of the three diagnostic criteria: polycystic ovaries in ultrasound, oligo or anovulation, and hyperandrogenism. The investigation ran from October 2023 until January 2024. The investigations of the patient were requested, and all data in the study were added.Results: Obese women with polycystic ovarian syndrome had significantly higher levels of waist circumference 102.75 ±1.45, prolactin 20.48 ±1.43, luteinizing hormone 7.85 ±0.56, Follicle-stimulating hormone 8.41 ±0.38, and lower levels of Peptide YY 45.33±16.62, and cholecystokinin 14.37 ±3.64.Conclusion: Low cholecystokinin and Peptide YY in obese polycystic ovarian syndrome women lead to a rise in appetite, intake of food, an increase in waist circumference, and accumulation of fat in the abdomen.
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Jeengar, Pooja, and Madhubala Chauhan. "Association of metabolic syndrome in polycystic ovarian syndrome." New Indian Journal of OBGYN 3, no. 2 (2017): 90–94. http://dx.doi.org/10.21276/obgyn.2017.3.2.5.

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8

Srinivas, G., D.V. Ramanjaneyulu, E. Muralinath, et al. "A Pathophysiology, Diagnosis, Differential Diagnosis and Treatment of Poly Cystic Ovarian Disease." Journal of Mental health, Psychiatric and Psychosocial Nursing 3, no. 1 (2024): 14–24. https://doi.org/10.5281/zenodo.14557185.

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<em>Among women of reproductive age, polycystic ovarian syndrome (PCOS) is the most prevalent hormonal condition. Polycystic ovaries, hyperandrogenism, and irregular menstrual cycles are some of its characteristics. The assessment and management of polycystic ovarian syndrome are explained in this activity, which also briefly goes over the function of the interprofessional team in treating patients with this illness.</em> &nbsp; <strong><em>Objectives</em></strong> &middot;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <em>Narrate</em><em> the epidemiology of polycystic ovarian syndrome.</em> &middot;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <em>Briefly r</em><em>eview the role of functional ovarian hyperandrogenism (FOH) in the pathophysiology of polycystic ovarian syndrome.</em> &middot;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <em>Compile</em><em> the use of the Rotterdam criteria in the evaluation of polycystic ovarian syndrome.</em> &middot;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <em>Summarize </em><em>the importance of collaboration and communication among the interprofessional team to emphasize lifestyle changes </em>
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9

Boqun, Xu, Dai Xiaonan, Cui YuGui, et al. "Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome." International Journal of Endocrinology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/367956.

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Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries.Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and surgical treatment with the signed consent form. The cellular localization of SET protein was observed by immunohistochemistry. The expression levels of SET protein were analyzed by Western Blot.Result. SET protein was expressed predominantly in the theca cells and oocytes of human ovarian follicles in both PCOS ovarian tissues and normal ovarian tissues. The level of SET protein expression in polycystic ovaries was triple higher than that in normal ovaries(P&lt;0.05).Conclusion. SET was overexpressed in polycystic ovaries more than that in normal ovaries. Combined with its localization in theca cells, SET may participate in regulating ovarian androgen biosynthesis and the pathophysiology of hyperandrogenism in PCOS.
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10

Muhammad, Bakhtyar Kamal. "Characteristics and Risk Factors for Polycystic Ovarian Syndrome Among Females." Kurdistan Journal of Applied Research 5, no. 1 (2020): 200–209. http://dx.doi.org/10.24017/science.2020.1.14.

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Polycystic ovary syndrome (PCOS) is a major endocrinal syndrome may affect the female at adult ages. In polycystic ovary, the ovarian seen that are enlarged and the investigation may base on ultra-sonographic detection. Polycystic ovarian syndrome always represents a spectrum of syndrome rather than the diseases. Also clinically presented by polycystic on ovarian and generally demonstrated by reversible. 104 female patients were examined, 18 (17.3%) of females were diagnosed with polycystic ovarian syndrome. The mean age was 24.62 ± 7.32 years (ranged from 15 month to 50 years-old). 17 (94.4%) of women were less than 25 years-old p-value=0.03, hormonal abnormality was the most frequent symptoms in relation to polycystic ovarian syndrome 10 (55.5%) and p-value=0.001. 16 (88.9%) of women experienced vaginal discharge p-value=0.09. In conclusion, one from six females is expected to experience polycystic ovarian syndrome. Young females are probably to be at a high risk for developing polycystic ovarian syndrome. Despite uncertain etiology of polycystic ovarian syndrome, marital status, stress or anxiety, doing a regular exercise and pregnancy are all related parameters to the incidence of polycystic ovarian syndrome. Additionally, Cases with high hormonal abnormality and vaginal excretion could be considerable indicators of polycystic ovarian syndrome.
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11

Muhammad, Bakhtyar Kamal. "Characteristics and Risk Factors for Polycystic Ovarian Syndrome Among Females." Kurdistan Journal of Applied Research 5, no. 1 (2020): 200–209. http://dx.doi.org/10.24017/science.2020.14.

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Polycystic ovary syndrome (PCOS) is a major endocrinal syndrome may affect the female at adult ages. In polycystic ovary, the ovarian seen that are enlarged and the investigation may base on ultra-sonographic detection. Polycystic ovarian syndrome always represents a spectrum of syndrome rather than the diseases. Also clinically presented by polycystic on ovarian and generally demonstrated by reversible. 104 female patients were examined, 18 (17.3%) of females were diagnosed with polycystic ovarian syndrome. The mean age was 24.62 ± 7.32 years (ranged from 15 month to 50 years-old). 17 (94.4%) of women were less than 25 years-old p-value=0.03, hormonal abnormality was the most frequent symptoms in relation to polycystic ovarian syndrome 10 (55.5%) and p-value=0.001. 16 (88.9%) of women experienced vaginal discharge p-value=0.09. In conclusion, one from six females is expected to experience polycystic ovarian syndrome. Young females are probably to be at a high risk for developing polycystic ovarian syndrome. Despite uncertain etiology of polycystic ovarian syndrome, marital status, stress or anxiety, doing a regular exercise and pregnancy are all related parameters to the incidence of polycystic ovarian syndrome. Additionally, Cases with high hormonal abnormality and vaginal excretion could be considerable indicators of polycystic ovarian syndrome.
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12

Alcalay, M., D. Bider, S. Lipitz, S. Mashiach, D. Levran, and J. Dor. "Polycystic ovarian syndrome." Gynecological Endocrinology 9, no. 2 (1995): 119–23. http://dx.doi.org/10.3109/09513599509160200.

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13

Madnani, Nina, Kaleem Khan, Phulrenu Chauhan, and Girish Parmar. "Polycystic ovarian syndrome." Indian Journal of Dermatology, Venereology, and Leprology 79, no. 3 (2013): 310. http://dx.doi.org/10.4103/0378-6323.110759.

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14

SHUKAR-UD-DIN, SHAZIA, SADAF AHMED ASIM, SYEDA RABIA, Rumina Tabassum, and Aisha Razzaque. "POLYCYSTIC OVARIAN SYNDROME;." Professional Medical Journal 20, no. 05 (2013): 719–25. http://dx.doi.org/10.29309/tpmj/2013.20.05.1208.

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Background: Polycystic ovarian syndrome is a common disease among the women in reproductive age group and morecommon in South Asian women. Clinical presentations include menstrual disorders, subfertility, obesity,hirsutism, acne vulgaris andacanthosis. Objectives: The objective of study was to investigate co relation between acne and polycystic ovaries and its relation tomenstrual irregularity. Methodology: A total of 56women were enrolled in the study from Outpatient Department of Obs&amp;Gynae andDermatology, Dow University Hosptial, Ojha campus by convenient sampling. It was cross sectional study, conducted from July 2012 toNovember 2012.Verbal consent was taken. Sociodemographic information,Anthropometric measurement (height, weight, BMI) andacne severity with affected area, menstrual irregularities were administered on pre designed questionnaire.Pelvic ultrasound forpolycystic ovaries and serum LH, FSH in follicular phase of menstrual cycle (2nd day) advised from Dow Radiology and Dow Labrespectively. Results: A total of56 patients of PCOS were enrolled during five month period. The mean age of patient was 21.1+_SD0.994. Frequency of acne was 32 (57.1%).The mean BMI was 19.66 +_SD 4.54. Face was the commonest area involved in 24 (42.9%).menstrual irregularity was found in 50 (89.4%) women. There was no statistically significant relation seen between acne andoligomenorrhea. (X2 = 0.55 , P = 0.45). It was also determined that there was no co relation seen between the acne and serumtestosterone level calculated by independent sample t test.(P = 0.17) but statistically significant association seen between severity ofacne and serum LH/FSH ratio. (t test =3.28, p= 0.004) Conclusion: Acne was found in 32 (57.1%) women with PCOS. The study resultsrevealed a significant association seen between severity of acne and serum LH/FSH ratio. Relation between acne and serum testosteronelevel was statistically insignificant.
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BUTT, KIRAN, FARAH DEEBA, and HAVAIDA ATTIQUE. "POLYCYSTIC OVARIAN SYNDROME;." Professional Medical Journal 19, no. 06 (2012): 786–88. http://dx.doi.org/10.29309/tpmj/2012.19.06.2483.

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Objective: The objective of the present study was to determine the changes in the glucose level and lipid profile in patients withpolycystic ovarian syndrome (PCOS). Study Design: Descriptive study. Place and Duration of the study: This study was conducted atInstitute of Molecular Biology and Biotechnology, The University of Lahore from June 2009 to June 2010. Patients and Methods: Total 50patients with PCOS were included and 50 age-matched control subjects were also selected for comparison. Their glucose levels and lipidprofile were assessed using commercial kits. The data thus obtained was subjected to statistical analysis. Results: Significant differences(P&lt;0.05) in fasting blood glucose level and individual parameters of lipid profile were observed in women with PCOS. A higher prevalence ofhypertriglyceridemia, hypercholesterolemia, higher LDL, lower HDL and higher fasting blood glucose levels was explored in PCOS womenthan controls. Conclusions: Abnormal glucose level and lipid profile in PCOS women showed that these women are at an increased risk ofdeveloping diabetes and subsequently cardiovascular diseases.
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Yasin, Misbah, and Fouzia Yasmeen. "POLYCYSTIC OVARIAN SYNDROME." Professional Medical Journal 21, no. 01 (2018): 179–84. http://dx.doi.org/10.29309/tpmj/2014.21.01.1918.

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Objectives: The objective of this study is to: describe the pattern of disease inpatients with polycystic ovarian syndrome. Data Source: Medline Data Base. Design Of Study:Descriptive case series study. Settings: Gynaecological Outpatient Department of Ghurki trustteaching hospital Lahore. Duration: 6months period, from 8th October 2012 to 7th April 2013.Materials &amp; Methods: Sixty cases of polycystic ovarian syndrome as diagnosed on ultrasoundwere selected. These cases were examined for height, weight, body mass index, hirsutism, acne,acnthosis nigricans, breast examination (galactorrhoea). These cases were investigated forblood sugar (random), Fasting Insulin, pelvic ultrasound, LH, FSH and serum prolactin. Results:The mean age of the patients were 24.93±5.67 years. There were 28 (47%) patients of menstrualdisturbance, 18 (30%) patients of subfertility, 9 (13%) of obesity. There were 13 (21.7%) patients2of BMI level of equal to or less than 25 kg/m and 47 (78.3%) patients of BMI level more than 252kg/m . There were 25 (41.7%) patients of hirsuitim, 14 (23.3%) patients of acne and 17 (28.3%)patients of acanthoris nigricans on physical examination. There were 28 (46.7%) patients of LHlevel of more than 10 IU/L (raised) and 1 (1.7%) patient of more than 350 mU/L prolactin (raised).The mean right ovary volume of the patients was 12.08±3.04 and mean left ovarian volume of thepatients was 11.86±4.83. Conclusions: Hirsutism and cycle disturbances are the major clinicalfeatures of polycystic ovarian syndrome patients. Obesity seems to be more prevalent inpolycystic ovarian syndrome patients. The ratio between LH and FSH as a diagnostic tool waslow in our patients.
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Saleem, Shemaila, Fauzia Hanif, and Amanat Ali. "POLYCYSTIC OVARIAN SYNDROME;." Professional Medical Journal 24, no. 06 (2017): 834–38. http://dx.doi.org/10.29309/tpmj/2017.24.06.1196.

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Background: Numerous ailments encompassing endometriosis, infertility andpolycystic ovarian syndrome (PCOS) are associated with Vitamin D deficiency. It is due to theexpression of vitamin D receptors in various tissues other than skeleton. Objectives: The currentstudy was conducted to compare the levels of vitamin D with body mass index in women withPCOS and healthy females of Rawalpindi. Study Design: Descriptive cross-sectional study.Period: 6 months. Setting: Research work was done at Railway Hospital (Gynecology andObstetrics Department), Rawalpindi in alliance with Islamic International Medical College,Rawalpindi. Materials and methods: A sample of 50 apparently healthy women and 100cases of polycystic ovarian syndrome in their reproductive age (15-45 years) were selectedafter diagnosis by the clinician. Data was assembled by using a pre-structured questionnaire.Data analysis was carried out using SPSS version 21. Results: Our results show that the bodymass index in patients with polycystic ovarian syndrome (27.094+4.369) was considerably(p-value &lt; 0.05) more in contrast to the healthy controls (20.739+3.452) but no significant(p-value &gt;0.05) difference was observed between vitamin D levels across a range of Bodymass indices among the controls and cases. Conclusion: No significant association betweenBMI and vitamin D status was found in healthy as well as PCO women.
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Harding, Emma. "Polycystic Ovarian Syndrome." InnovAiT: Education and inspiration for general practice 3, no. 2 (2010): 71–75. http://dx.doi.org/10.1093/innovait/inp124.

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19

Abell, Sue, and John L. Ey. "Polycystic Ovarian Syndrome." Clinical Pediatrics 47, no. 9 (2008): 969–70. http://dx.doi.org/10.1177/0009922807303932.

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20

Можейко, Л. Ф. "Polycystic Ovarian Syndrome." Рецепт 27, no. 2 (2024): 205–13. http://dx.doi.org/10.34883/pi.2024.27.2.006.

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Актуальность проблемы синдрома поликистозных яичников (СПКЯ) заключается не только в высокой степени распространения этой патологии, но и в ее социальной значимости, что обусловлено частым сочетанием нарушений менструальной функции, метаболических расстройств с проявлениями гиперандрогении (гирсутизм, себорея, акне), ановуляторного бесплодия, которые нередко становятся причиной нарушений психологического статуса и качества жизни. Несмотря на значительные достижения последних десятилетий, единой концепции этиопатогенеза СПКЯ не существует, а вопросы диагностики и лечения этой патологии продолжают оставаться дискутабельными. В подростковом возрасте СПКЯ является диагнозом исключения, поскольку может быть верифицирован после исключения других заболеваний со сходной клинической симптоматикой. В статье представлены основные диагностические критерии синдрома поликистозных яичников у подростков, современные подходы тактики ведения и лечения таких пациентов. The relevance of the problem of polycystic ovary syndrome (PCOS) lies not only in the high degree of prevalence of this pathology, but also in its social significance, which is due to the frequent combination of menstrual dysfunction, metabolic disorders with manifestations of hyperandrogenism (hirsutism, seborrhea, acne), anovulatory infertility, which often cause psychological status disorders. and quality of life. Despite the significant achievements of recent decades, there is no single concept of the etiopathogenesis of PCOS, and the issues of diagnosis and treatment of this pathology continue to be debatable. In adolescence, PCOS is a diagnosis of exclusion, as it can be verified after the exclusion of other diseases with similar clinical symptoms. The article presents the main diagnostic criteria for polycystic ovary syndrome in adolescents, modern approaches to the management and treatment of such patients.
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Gihan, M. C., A. A. W. M. Wijerathna, and P. A. C. P. Pathiraja. "Polycystic ovarian syndrome." Sri Lanka Journal of Obstetrics and Gynaecology 46, no. 1 (2024): 11–16. http://dx.doi.org/10.4038/sljog.v46i1.8118.

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The most common hormonal disorder in women at reproductive age is the Polycystic Ovary Syndrome (PCOS) and the complex pathophysiology of PCOS and its substantial health repercussions, which include obesity, cancer, cardiovascular disease, diabetes, and psychological morbidities, have made it a major global health concern for women. The aim of the present review article is to summarize the literature available on PCOS and to identify the pathophysiology, diagnosis criteria and the treatments for the disease.
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Kelley, Larry S. "Polycystic Ovarian Syndrome." AAOHN Journal 51, no. 1 (2003): 23–27. http://dx.doi.org/10.1177/216507990305100107.

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Khan, Khurshid A., Sameer Stas, and L. Romayne Kurukulasuriya. "Polycystic Ovarian Syndrome." Journal of the CardioMetabolic Syndrome 1, no. 2 (2006): 125–32. http://dx.doi.org/10.1111/j.1559-4564.2006.05675.x.

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24

Ruby, Laura A. "Polycystic Ovarian Syndrome." Journal for Nurse Practitioners 4, no. 9 (2008): 697–704. http://dx.doi.org/10.1016/j.nurpra.2008.08.005.

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Trikudanathan, Subbulaxmi. "Polycystic Ovarian Syndrome." Medical Clinics of North America 99, no. 1 (2015): 221–35. http://dx.doi.org/10.1016/j.mcna.2014.09.003.

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26

Mishra, S., and A. Shrestha. "Polycystic Ovarian Syndrome." Journal of Universal College of Medical Sciences 1, no. 1 (2013): 39–41. http://dx.doi.org/10.3126/jucms.v1i1.8423.

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27

Punam, Raut* Shivprasad Deokar Dr. Kawade Rajendra. "Polycystic Ovarian Syndrome." International Journal of Pharmaceutical Sciences 2, no. 11 (2024): 1211–24. https://doi.org/10.5281/zenodo.14211805.

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The polycystic ovarian disorder (PCOS) is defined as a combination of hyperandrogenism (hirsutism and skin breakouts) and anovulation (oligomenorrhea, barrenness, and ineffective uterine leaking), with or without the presence of polycystic ovaries on ultrasound. It addresses the fundamental endocrine issue in the conceptional age, which affects 6%-15% of women in danger. It is the most generally recognized cause of barrenness due to anovulation and the predominant cause of female fruitlessness. PCOS is discovered in 30%-40% of individuals with essential or auxiliary amenorrhea and 80% of people with oligomenorrhea before the onset of a menstrual problem. PCOS should be diagnosed and treated early in life due to the conceptive, metabolic, and ontological issues that may be associated with it. Medication, food, and lifestyle changes are all possible treatment options. The likelihood of becoming pregnant varies among healthy young couples. In 2010, an estimated 48.5 million couples worldwide were infertile. This study provides a survey of barrenness causes, examinations, treatment modalities, and the role of a medical attendant birthing specialist in managing infertile couples. Barrenness (a condition of sub-richness) can be defined as the failure to become pregnant, the inability to maintain a pregnancy, or the failure to carry a pregnancy to term. Male and female infertility have various causes.
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Al Ghazali, Basima Shamkhi, and Sara Monther. "Serum Mannose Level and Its Association in Women with Polycystic Ovarian Syndrome: a Case Control Study of Al-Najaf City / 2020." Kufa Medical Journal 18, no. 1 (2022): 1–10. http://dx.doi.org/10.36330/kmj.v18i1.3273.

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Background: Polycystic ovarian syndrome is a common public health issue around the world. Insulin resistance and glucose intolerance play important role in the etiology of polycystic ovarian syndrome and the serum mannose is incorporated in metabolism of glucose. Aim of study: Determination of the association between serum mannose level and polycystic ovarian syndrome. Patients and Methods: A case control study enrolled eighty eight women were divided as forty four women with polycystic ovarian syndrome and forty four women without polycystic ovarian syndrome presented to outpatient clinic at Fertility Center/Al Sader Medical City and outpatient clinic of Al- Zahraa Teaching Hospital in Najaf city-Iraq during the period from 1st of February till 31st of December, 2020. Results: The mean Serum Mannose level of women with polycystic ovarian syndrome 7.37 was significantly higher than mean serum mannose of controls 1.32 (p&lt;0.001). Cutoff serum mannose level of 1.98 had acceptable validity results (90.9% sensitivity, 90.9% specificity, 94% PPV, 90.5% NPV and 90% accuracy). The means of serum level testosterone and luteinizing hormones were significantly higher among women with polycystic ovarian syndrome, while mean follicular stimulating hormone level was significantly lower among women with polycystic ovarian syndrome. Conclusions: The serum mannose level is significantly increased in women with polycystic ovarian syndrome which may indicate its possible role in the pathophysiology of polycystic ovarian syndrome.
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Imtiaz, Sadaf, Pashmina Gul, Shizra Shahnawaz, Tabassum Zarrar, Kaneez Kubra, and Sajida Akram. "Frequency of Metabolic Syndrome in Patients with Polycystic Ovarian Syndrome." Life and Science 4, no. 3 (2023): 7. http://dx.doi.org/10.37185/lns.1.1.360.

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Objective: To study the frequency of metabolic syndrome in patients with polycystic ovarian syndrome.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the outpatient Department of Gynecology Unit-II from 1st September 2019 to 25th January 2020.Materials and Methods: Females aged 18 to 45 years were diagnosed with polycystic ovarian syndrome using Rotterdam criteria. The diagnosis of metabolic syndrome was made upon the Adult Treatment Panel criteria National Cholesterol Education Program Expert Panel, i.e., the presence of any three features like central obesity, dyslipidemia, hypertension, and elevated fasting blood sugar. All procedures were done by the researcher herself, and all data were recorded on a pre-designed questionnaire. Data was analyzed using SPSS version 25.Results: The average age of the females was 30.98±7.05 years, most of whom were married (96.62%). Out of the total 148 females, 64.83% were diabetic, 29.73% had hypertension, 69.59% had dyslipidemia, and 29% were obese. Out of 148 females with polycystic ovarian syndromes, metabolic syndrome was present in 27.70%. The frequency of metabolic syndrome was significantly higher among obese females compared to normal and overweight with p-value=0.001. However, metabolic syndrome showed no significant association with age, marital status, parity, and duration of polycystic ovarian syndrome (p&gt;0.05).Conclusion: Metabolic syndrome is a prevalent condition in females with polycystic ovarian syndrome and having a high BMI makes it more likely. These findings andsystematic investigation can be used to justify a metabolic syndrome screening policy in polycystic ovarian syndrome for early detection and intervention, as well as a healthy future.
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Gavali, Dr Urmila, Dr Mayuri Pawar, Dr Gautam Aher, and Dr Suhas Shinde. "Clinical Profile of Polycystic Ovarian Syndrome Patients In Tertiary Care Hospital." VIMS Health Science Journal 8, no. 3 (2021): 99–103. http://dx.doi.org/10.46858/vimshsj.8303.

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ABSTRACT:&#x0D; Background: Polycystic ovarian syndrome (PCOS)is common gynecological endocrinopathy characterized by chronic anovulation and hyperandrogenism affecting 5-10% of women worldwide. It is a heterogenous, multifactorial, complex genetic disorder with uncertain etiology and is one of the most common treatable cause of infertility.&#x0D; AIM: To study the various clinical presentations in polycystic ovarian syndrome.&#x0D; MATERIALS AND METHODS: Present study is cross sectional observational study carried out in tertiary care centre. This study was performed in the Out Patient Department of Obstetrics and Gynecology.&#x0D; RESULTS: The mean age of 41 patients in the study was 23.6 years. Most common presenting symptom in patients is menstrual irregularities (89%) followed by infertility and hirsutism. USG (abdo+pelvis) showing polycystic ovarian syndrome ovaries. Around 39% patients with PCOS developed insulin resistance.&#x0D; KEYWORDS: - Amenorrhea, Infertility, Oligomenorrhea, Polycystic Ovarian Syndrome.
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Gavali, Dr Urmila, Dr Mayuri Pawar, Dr Gautam Aher, and Dr Suhas Shinde. "Clinical Profile of Polycystic Ovarian Syndrome Patients In Tertiary Care Hospital." VIMS Health Science Journal 8, no. 3 (2021): 99–103. http://dx.doi.org/10.46858/vimshsj.8303.

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ABSTRACT:&#x0D; Background: Polycystic ovarian syndrome (PCOS)is common gynecological endocrinopathy characterized by chronic anovulation and hyperandrogenism affecting 5-10% of women worldwide. It is a heterogenous, multifactorial, complex genetic disorder with uncertain etiology and is one of the most common treatable cause of infertility.&#x0D; AIM: To study the various clinical presentations in polycystic ovarian syndrome.&#x0D; MATERIALS AND METHODS: Present study is cross sectional observational study carried out in tertiary care centre. This study was performed in the Out Patient Department of Obstetrics and Gynecology.&#x0D; RESULTS: The mean age of 41 patients in the study was 23.6 years. Most common presenting symptom in patients is menstrual irregularities (89%) followed by infertility and hirsutism. USG (abdo+pelvis) showing polycystic ovarian syndrome ovaries. Around 39% patients with PCOS developed insulin resistance.&#x0D; KEYWORDS: - Amenorrhea, Infertility, Oligomenorrhea, Polycystic Ovarian Syndrome.
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Sobia Ali, Hajira Ishaq, Naheed Khattak, et al. "ASSOCIATION OF C-REACTIVE PROTEIN WITH HYPERLIPIDEMIA IN PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME IN KHYBER PAKHTUNKHWA." Journal of Ayub Medical College Abbottabad 34, no. 3 (2022): 546–49. https://doi.org/10.55519/jamc-03-10836.

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Background: It has been unknown whether there exist any relations of C-Reactive Protein (CRP) level with hyperlipidaemia in polycystic ovarian syndromes patients. To determine Association of CRP with Hyperlipidaemia in patients with polycystic ovarian syndrome. Method: This was a cross sectional descriptive study conducted among 50 each polycystic ovarian syndrome and normal women. After taking a written consent from participants predesigned questionnaire was filled including information regarding demography and medical history. A 3 to 5 ml blood was taken from patients and controls and transferred to laboratory for determination of CRP level and lipid profile. The test results were collected, compiled, entered and analyzed using SPSS Version 20 for determination of any kind of association of CRP with Hyperlipidaemia in patients with polycystic ovarian syndrome. Results: The mean age of study participants was 29.72±4.00 for cases and 29.04±3.99 for control. The cases and control were with the same age range, however there was a significant difference p=0.00 in BMI of the cases and control. There was no significant association observed between CRP and lipid profile parameters among polycystic ovarian syndrome patients. Conclusion: There exist no association between increasing CRP level and hyperlipidaemia in polycystic ovarian syndrome patients however CRP and lipid profile parameters showed high values among these patients.
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Nalini Anjaneya Sridhar, Kollati. "Folliculinum in Treatment of Polycystic Ovarian Syndrome." International Journal of Science and Research (IJSR) 11, no. 11 (2022): 1350–51. http://dx.doi.org/10.21275/sr221126173014.

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Di Pietro, Mariana, Natalia Pascuali, Fernanda Parborell, and Dalhia Abramovich. "Ovarian angiogenesis in polycystic ovary syndrome." Reproduction 155, no. 5 (2018): R199—R209. http://dx.doi.org/10.1530/rep-17-0597.

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Polycystic ovary syndrome (PCOS) is the most prevalent endocrine pathology among women in reproductive age. Its main symptoms are oligo or amenorrhea, hyperandrogenism and the presence of ovarian cysts. It is also associated with infertility, obesity and insulin resistance. Mainly due to its heterogeneity, PCOS treatments are directed to manage its symptoms and to prevent associated diseases. The correct formation and regression of blood vessels during each ovarian cycle is indispensable for proper follicular development, ovulation and corpus luteum formation. The importance of these processes opened a new and promising field: ovarian angiogenesis. Vascular alterations characterize numerous pathologies, either with increased, decreased or abnormal angiogenesis. In the last years, several anomalies of ovarian angiogenesis have been described in women with PCOS. Therefore, it has been suggested that these alterations may be associated with the decreased – or lack of – ovulation rates and for the formation of cysts in the PCOS ovaries. Restoration of a proper vessel formation in the ovaries may lead to improved follicular development and ovulation in these patients. In the present review, we attempt to summarize the alterations in ovarian angiogenesis that have been described in women with PCOS. We also discuss the therapeutic approaches aimed to correct these alterations and their beneficial effects on the treatment of infertility in PCOS.
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Umar, Mohammad Khan Siddqui Mohammad Fardeen* Thorat Dharmesh Jitendra Quazi Majaz Aejaz Ahmed. "Review Article On Polycystic Ovary Syndrome." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 147–54. https://doi.org/10.5281/zenodo.10781584.

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PCOS, also known as polycystic ovarian syndrome, is a prevalent infertility condition that impacts a noteworthy segment of the worldwide populations. With a prevalence of 8&ndash;13%, depending on the criteria applied and population investigated, it is the most frequent endocrinopathy affecting women of reproductive age and the primary cause of anovulatory infertility in women. Although polycystic ovaries have been described since 1721, Stein and Leventhal were the first to report the condition. Polycystic ovarian disease (PCOD) is the term used to describe the condition when polycystic ovaries are discovered in healthy women. Formal diagnostic criteria were not proposed or widely used until a PCOS meeting sponsored by the National Institutes of Health (NIH) in the early 1990s. Numerous researchers conducted numerous experiments and attempted to explain the pathophysiology of PCOS.
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Patil, Poonam Sambhaji, and Namit Kudatarkar. "Assessing the therapeutic potential of Banana blossom extract in ameliorating Mifepristone-Induced Polycystic Ovarian Syndrome in Rat Model." International Journal of Ayurvedic Medicine 15, no. 4 (2025): 890–98. https://doi.org/10.47552/ijam.v15i4.5155.

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Background: Polycystic ovarian syndrome (PCOS) is a syndrome defined by ovarian dysfunction which is marked primarily by elevated hormone levels and the presence of polycystic ovaries discovered on ultrasonography. Polycystic ovarian syndrome is an extremely prevalent lifestyle disorder that affects 6 out of 10 women. The management of polycystic ovarian syndrome is largely unclear. This study examines the possible use of Banana Blossom an herbal therapy in a rat model of polycystic ovarian syndrome caused by the medication mifepristone. Methods: For 13 days, female Wistar rats were given 20mg/kg b.w. of mifepristone daily to induce PCOS, which was verified by the sustained estrous cycle. The rats received treatment with Banana Blossom extract orally for 21 days at a dosage of 200, 400 and 800mg/kg b.w. after PCOS induction and standard treatment was metformin. Physical, biochemical parameter and oxidative stress marker was carried out using standard procedure. Result: The PCOS rats reported a significant decline (P˂0.001) in uterine weight, HDL, SOD as well as GSH levels along with a significant rise (P˂0.001) in body weight, periovarian fat, LDL, triglycerides, MDA and glucose level. Banana Blossom extract reversed these effects, with the 800mg/kg b.w. dose providing the most significant improvements in oxidative stress markers and biochemical parameters. Conclusion: After analysing the data, one can conclude that the banana blossom ethanolic extract exhibited an improved therapeutic effect on mifepristone induced polycystic ovarian syndrome in female Wistar rats.
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37

Azizova, M. E. "Polycystic ovary syndrome - modern concepts." Kazan medical journal 96, no. 1 (2015): 77–80. http://dx.doi.org/10.17750/kmj2015-077.

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The article reviews current concepts of etiology and pathogenesis of polycystic ovary syndrome. Currently, numerous forms of the syndrome, manifesting by a variety of clinical, morphologic signs and features of endocrine profile, exist. It was revealed that polycystic ovary syndrome is a multifactorial, genetically determined disease. Laboratory diagnosis in females with polycystic ovary syndrome is based on measuring concentrations of hormones. Results of ovarian sonography are of a great importance, allowing to diagnose polycystic ovary syndrome. Another method of instrumental diagnosis is laparoscopy, revealing two-sided growth ovarian hypertrophy and multiple subcapsular cysts. Ovarian capsule looks thickened, smooth, with a marked vascular pattern. Treatment depends on the clinical features and intensity of symptoms, as well as on patient’s interest in pregnancy. The choice of treatment options should be supported by clinical and laboratory data, considering pathogenetic type of the disease. The treatment of polycystic ovary syndrome includes conservative and surgical approaches. The main targets of drug treatment is the cessation of clinical and metabolic symptoms of the disease, decreasing the symptoms of virilescence, restoring the menstrual cycle and ovulation induction. Indication for surgical treatment is non-efficiency of drug treatment in restoring fertility. Thereby, multiple factors determining clinical symptoms and morphologic changes in ovaries, including central mechanisms of pituitary gland gonadotropic function, local ovarian factors, extraovarial endocrine and metabolic disorders, participate in pathogenesis of polycystic ovary syndrome. The early initiation of treatment in patients with polycystic ovary syndrome may preserve the fertility, as well as prevent hyper- and neoplastic diseases of endothelium, and the syndrome’s late complications.
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Ságodi, László, Ildikó Schmidt, Ildikó Vámosi, and László Barkai. "Peripubertal ovarian cyst torsion as an early complication of undiagnosed polycystic ovarian syndrome." Orvosi Hetilap 154, no. 3 (2013): 113–17. http://dx.doi.org/10.1556/oh.2013.29520.

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The aim of the authors is to present two cases which raise the possibility of an association between polycystic ovarian syndrome/hyperandrogenism and ovarian cyst torsion in peripubertal girls. Androgen excess may cause more frequently ovarian cyst formation in premenarcheal or young adolescents with undiagnosed polycystic ovarian syndrome than in adults. The authors recommend that polycystic ovarian syndrome as wel as late onset congenital adrenal hyperplasia should be considered in peripubertal adolescents with ovarian cyst torsion. In case polycystic ovarian syndrome is confirmed, adequate management according to age and pubertal development of the patients should be commenced. Orv. Hetil., 2013, 154, 113–117.
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Bahadori, Atekeh, Afrouz Khazamipour, and Dariush D.Farhud. "Genetics Poly Cystic Ovary Syndrome." Asian Pacific Journal of Cancer Biology 1, no. 4 (2016): 97–105. http://dx.doi.org/10.31557/apjcb.2016.1.4.97-105.

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Background: Polycystic ovarian syndrome is a complicated hereditary disorder which does not have specific reason and 6-10% of women at fertility age are involved. In other word we can say that this syndrome is a familial hereditary syndrome which developed with combination of environmental and genetic factors. Polycystic ovarian syndrome (PCOS) is related to cardiovascular diseases and has psychological and neurological effects on life quality as well as uterine and breast cancers. The main criteria for diagnosis of polycystic ovarian syndrome are chronic anovulation and hyperandogenism and the sub-criteria are insulin resistance, hirsutism and obesity onset at menarche age, anovulation alternatively is associated with increased testosterone level and DHEA-S. The cause of polycystic ovarian syndrome (PCO) is unknown, but it could be the result of complex genetic factors which are evident at puberty onset, also hereditary and non-hereditary factors could be the cause of polycystic ovarian syndrome (PCO) pheno ype. In many women with polycystic ovarian syndrome, the insulin level is high. It seems that high levels of insulin increase androgens production. High levels of androgens can cause acne, supernumerary hair growth, weight gain, and ovulation problem.Conclusion: Early diagnosis and treatment of polycystic ovarian syndrome could help to reduce long-term complications such as diabetes type II, high blood pressure, heart disease and stroke.
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40

Hasan, Iman Jaber Hasan. "Study thyroid gland hormones in female with polycystic ovary syndrome: A Review." University of Thi-Qar Journal of agricultural research 13, no. 1 (2024): 9–16. http://dx.doi.org/10.54174/utjagr.v13i1.298.

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One metabolic syndrome is polycystic ovarian syndrome (PCOS) marked by polycystic ovary the hyperandrogenism, and anovulation. PCOS affects 6–10% of women in their reproductive years. It is a common condition. When no other cause can be identified, polycystic ovaries, hyperandrogenism, and/or irregular ovulation are the hallmarks of polycystic ovarian syndrome (PCOS). Since frank (overt) hypothyroidism is linked to insulin resistance, dyslipidemia, weight gain, anovulatory cycles, decreased levels of SHBG, and infertility, it shares several characteristics with the PCOS phenotype. Thyroid disorder screening is part of the recommended baseline screening for women who may be suspected of having PCOS, irregular menses, or infertility.Insulin resistance plays a role in PCOS pathogenesis.
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Varnika, Rastogi, Verma Namrata, Srivastava Akanksha, and Kahar Govind. "Assessment of Metabolic Syndrome in Women with Polycystic Ovarian Syndrome – A Cross-Sectional Study." International Journal of Pharmaceutical and Clinical Research 14, no. 8 (2022): 978–83. https://doi.org/10.5281/zenodo.13363166.

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<strong>Background:</strong>&nbsp;Polycystic ovarian syndrome is a prevalent disorder among women of the reproductory age group. It results in an increased stress level in the body resulting in the rise of inflammatory markers. This leads to infertility, lipid derangement, risk of type 2 diabetes &amp; atherosclerosis. Early screening is required for proper management &amp; preventing the serious sequelae &amp; reduce the disease burden. Thus, this cross-sectional study was undertaken to assess metabolic syndrome in women with the polycystic ovarian syndrome with the controls.&nbsp;<strong>Material &amp; Methods:</strong>&nbsp;This cross-sectional study recruited 100 women in the age range of 15-35 years who visited the Department of Obstetrics and Gynecology in G S Medical College and Hospital, Pilkhuwa, Uttar Pradesh from January 2022 to June 2022. Group, I included healthy women in the age range of 15-35 years having documented features of PCOS (according to Rotterdam criteria, 2003) (n=50) &amp; Group II included controls (n=50). Patients were excluded if they had diabetes, hypertension, cardiovascular disease, or pregnancy. Fasting plasma glucose, Systolic blood pressure, diastolic blood pressure, Waist circumference, Serum triglyceride &amp; HDL cholesterol were recorded (according to NCEP criteria).&nbsp;<strong>Results:</strong>&nbsp;The mean age of the participants in Group I &amp; Group II were 24.54&plusmn;3.42 yrs &amp; 26.23&plusmn;6.71 yrs respectively. Thus, the mean age in Group I was lower than that of Group II but was not statistically significant (p&gt;0.05). Waist circumference, SBP, DBP, fasting blood sugar &amp; serum triglyceride levels were statistically significantly higher in Group I (p&lt;0.05). HDL cholesterol levels were statistically significantly higher in Group II (p&lt;0.05). In Group I, 71% of the patients had obesity, 76% presented with hyperandrogenemia,94% with Oligo/amenorrhea, 15% had primary infertility, 9% had secondary infertility &amp; 65% had polycystic ovaries on ultrasonography.&nbsp;<strong>Conclusion:</strong>&nbsp;A positive association between polycystic ovarian syndrome and metabolic disorders in females has been demonstrated. The metabolic syndrome is common in polycystic ovarian syndrome, among women with hyperinsulinemia and obesity. Regular screening &amp; timely intervention emphasizing the importance of a healthy lifestyle can prevent the development of metabolic disorders &amp; polycystic ovarian syndrome in women. &nbsp; &nbsp; &nbsp;
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Abhilasha and Prof. Charu Vyas. "Awareness Regarding Polycystic Ovarian Syndrome Among Adolescent Girls." International Journal of Scientific Research in Science and Technology 11, no. 2 (2024): 929–35. http://dx.doi.org/10.32628/ijsrst24112153.

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The present study was conducted on “Awareness regarding polycystic ovarian syndrome among adolescent girls” with the objectives to assess awareness level regarding polycystic ovarian syndrome among adolescent girls, and to find out the problems faced by polycystic ovarian syndrome girls. The study was conducted on 100 students of B.B.A, B.A and B.des 1st year from Banasthali Vidyapith. Self-constructed questionnaire tool was used for this study. For analyzing the data following statistical measures were used such as mean, frequency, percentage, and One-Way ANOVA. The result of the study revealed that there is no significant difference in awareness level between B.A, B.B.A and B.des 1st year students. 50% of students come under the below-average category, 30% of students come under the average category, and 20% of students come under the above-average category of awareness about polycystic ovarian syndrome. All students had a low level of awareness regarding polycystic ovarian syndrome so they needed an awareness program to increase knowledge about polycystic ovarian syndrome.
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Siddharth Bharatbhai, Rajpura, and Desai Archish Ishvarbhai. "Metabolic Syndrome among Polycystic Ovarian Syndrome: A Cross Sectional Study." Indian Journal of Obstetrics and Gynecology 7, no. 1 (2019): 65–71. http://dx.doi.org/10.21088/ijog.2321.1636.7119.12.

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44

Tanvir, Seema. "Polycystic Ovarian Syndrome: A Syndrome Entailing early Diagnosis and Treatment." International Journal of Nursing & Midwifery Research 05, no. 03 (2018): 81–85. http://dx.doi.org/10.24321/2455.9318.201837.

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Okanovic, Milana, and Olga Zivanovic. "Valproate, bipolar disorder and polycystic ovarian syndrome." Medical review 69, no. 3-4 (2016): 121–26. http://dx.doi.org/10.2298/mpns1604121o.

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Introduction. Polycystic ovarian syndrome is a syndrome of ovarian dysfunction with the principal features of hyperandrogenism and polycystic ovary morphology. A large number of studies conducted on this topic have suggested a possible role of anticonvulsants, particularly valproate, in the pathogenesis or risk factors associated with polycystic ovarian syndrome. Bipolar treatment guidelines from Canada and the United States of America recommend valproate as the first line strategy in the acute treatment of bipolar disorder. Discussion. Most persons with bipolar disorder require maintenance treatment. Long-term administration of valproate in women with bipolar disorder or epilepsy is believed to result in the increased risk of hyperandro?genism, menstrual abnormalities and polycystic ovaries. Valproate may also increase the risk of infertility and other associated symptoms of polycystic ovarian syndrome. Therefore, particular caution is indicated in the use of valproate in women of reproductive age. Conclusion. The treatment of the female patients with bipolar disorder presents various challenges for the clinician. Every woman of reproductive age needs to know the risk and benefits of her pharmacologic treatment options. Bipolar disorder should be considered chronic disorder, whose development is largely affected by hormonal changes and reproductive cycle in women. These issues should be researched more thoroughly in order to opt for the most appropriate treatment in women with bipolar disorder.
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Sarwade, Prakash Pralhad, B. Dhanasree, Kavita Narayan Gaisamudre (Sarwade), et al. "Natural Chemical Constituents and Polymer Used in to Reduce PCOS Pain." Journal for Research in Applied Sciences and Biotechnology 4, no. 1 (2025): 88–99. https://doi.org/10.55544/jrasb.4.1.10.

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The complex metabolic and endocrine disorder known as polycystic ovarian syndrome (PCOS) is characterised by anovulation, infertility, obesity, insulin resistance, and polycystic ovaries. Factors that predispose women to polycystic ovarian syndrome encompass dietary and lifestyle decisions, environmental pollutants, genetic predisposition, gut dysbiosis, alterations in neuroendocrine function, and excess adiposity. Hyperinsulinemia, oxidative stress, hyperandrogenism, inadequate folliculogenesis, and irregular menstrual periods are symptoms that may arise from these variables, potentially contributing to an escalation of metabolic syndrome. Pathogenic dysbiosis of the gut microbiota may have a role in the aetiology of polycystic ovarian syndrome (PCOS). Immature oocytes, insulin resistance, hyperandrogenism, inflammation, oxidative stress, and resveratrol are pathological features of PCOS that may be ameliorated by supplementation with natural compounds such as polyphenols, quercetin, resveratrol, flavonoids, vitamin C, gamma-linolenic acid, piperine, and omega-3 fatty acids, along with natural and semi-synthetic polymers. This review encapsulates the current understanding of the efficacy of natural chemical supplementation in the treatment of PCOS.
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47

MUNSON, BECKY LIEN. "… About polycystic ovarian syndrome." Nursing 32, no. 11 (2002): 78. http://dx.doi.org/10.1097/00152193-200211000-00053.

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48

Edmondson, Emily S. "Understanding Polycystic Ovarian Syndrome." Physician Assistant Clinics 3, no. 3 (2018): 353–62. http://dx.doi.org/10.1016/j.cpha.2018.02.004.

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49

M, Najimudeen,, Myo HLA Myint, Anisah, J, Winson, S. M, and Thavamani, R. M. "Polycystic Ovarian Syndrome- Revisited." Scholars International Journal of Obstetrics and Gynecology 6, no. 03 (2023): 84–91. http://dx.doi.org/10.36348/sijog.2023.v06i03.001.

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Polycystic ovarian syndrome (PCOS) is a complex condition. In PCOS the metabolic and endocrine components are affected. The PCOS is an evolving condition and therefore has variable ultrasound presentations. Inappropriate gonadotrophin secretion causes ovarian dysfunction. Increased level of plasma testosterone is a common feature in PCOS. Women with PCOS have abnormalities in the metabolism of androgens and oestrogen. PCOS is a genetically heterogeneous syndrome. The abnormal menstruation patterns in PCOS is attributed to chronic anovulation. Women with PCOS should be assessed for their cardiovascular risk. The lifestyle modifications such as reducing the weight, increasing the exercise and restriction of carbohydrate intake consistently reduce the risk of diabetes. Medical management of PCOS is aimed at the treatment of metabolic derangements, anovulation, hirsutism and menstrual irregularity. The surgical management of PCOS is aimed mainly to improve ovulation. PCOS has many long-term complications. Therefore the patients need regular follow-up with their physicians for early detection and management of any untoward sequelae associated with the syndrome.
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Siddiqui, Tazeen, and Shweta Sawant. "THE EFFECT OF LOWER EXTREMITY CLOSED KINEMATICS CHAIN EXERCISE ON POLYCYSTIC OVARIAN SYNDROME WITH MENORRHEA." International Journal of Advanced Research 12, no. 05 (2024): 430–34. http://dx.doi.org/10.21474/ijar01/18733.

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Aim:This study investigated the effect of lower extremity closed kinematics chain exercise on polycystic ovarian syndrome with menorrhea. Method:A total of 35 subject young women with polycystic ovarian syndrome between the age of 18 to 30 years, were recruited over 6 months and randomly allocated to an intervention group(n=35), participated in this observational experimental study. In this study menorrhea flow were measured at baseline prior to enrolment after 6 months of participation. In an intention-to-treat analysis, we experiment the closed kinematics chain exercise is effective in polycystic ovarian syndrome with menorrhea. Result: Result of this study were analysed in terms effect of lower extremity closed kinematics chain exercise on menorrhea with polycystic ovarian syndrome patient the population of 35 subjects [all females] were served for effect of lower extremity of closed kinematics exercise on patients with menorrhea in polycystic ovarian syndrome in age group of 18 to 30 yrs. Out of 35 patients Pads count are compared between pre and post result and same in result is seen in Menorrhea outcome questionnaire score. The study states that pads count and menorrhea outcome questionnaire score for menorrhea in polycystic ovarian syndrome patient is showed that improve after lower extremities closed kinematics chain exercise. Conclusion: The study concluded that conventional physiotherapy with lower extremity closed kinematics chain exercises are effective in reducing menorrhea in patient with polycystic ovarian syndrome.
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