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1

Gursu, Turkan, Halime Cevik, Güldeniz Aksan Desteli, Birnur Yilmaz, Tevfik Berk Bildaci, and Alper Eraslan. "Diagnostic value of shear wave velocity in polycystic ovarian syndrome." Journal of Ultrasonography 21, no. 87 (November 29, 2021): 277–81. http://dx.doi.org/10.15557/jou.2021.0047.

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Aim: In polycystic ovarian syndrome, the ovaries become stiffer due to chronic anovulation. We aimed to compare tissue elasticity in terms of shear wave velocities measured using acoustic radiation force impulse imaging technique between the ovaries of polycystic ovarian syndrome women and non-polycystic ovarian syndrome women. Material and methods: The study was designed as a retrospective data analysis of women who underwent transvaginal ultrasound and acoustic radiation force impulse imaging in a university hospital between July 2014 and March 2015, for various reasons. There were 32 polycystic ovarian syndrome patients and 32 patients without a diagnosis of polycystic ovarian syndrome. Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, prolactin, antimullerian hormone levels, and menstrual patterns with clinical hyperandrogenism were evaluated. On the menstrual cycle days 2–4, by performing a transvaginal ultrasound scan, the ovarian volumes and antral follicle counts in both ovaries were recorded for each woman. The ultrasound system was converted into the elastography mode, and acoustic radiation force impulse imaging was performed. Shear wave velocity (m/sec) was measured at least 5 times for each ovary, and the mean value was calculated for each polycystic ovarian syndrome and non-polycystic ovarian syndrome woman. Results: Age, body mass index, fasting glucose levels, cycle day 3 follicle stimulating hormone, luteinizing hormone, thyroid stimulating hormone, and prolactin levels were similar between the groups (p >0,05). Antimullerian hormone levels, antral follicle counts, and mean ovarian volumes were statistically different between the groups (p <0,05). Mean shear wave velocity values for both ovaries were 2.12 ± 0.82 (0.78–4.9) m/sec in the polycystic ovarian syndrome group, and 1.18 ± 0.41 (0.77–2.0) m/sec in the non-polycystic ovarian syndrome group, which was statistically significantly different (p = 0.016). Conclusion: In our study, we found significantly higher shear wave velocity levels in polycystic ovarian syndrome women than non-polycystic ovarian syndrome women, which indicates an impact of the condition on shear wave velocity. The increased acoustic frequencies cause a decreased response in time to transition, and motion becomes out of phase; in other words, scattered waves are faster in stiffer ovaries. Our results are thus compatible with the pathophysiology of the disease. Shear wave velocity is a beneficial tool for evaluating ovarian elasticity in polycystic ovarian syndrome patients in whom the levels are found to be significantly higher than non-polycystic ovarian syndrome women. In light of these findings, shear wave velocity is expected to be slower than polycystic ovarian syndrome levels in ovulatory women.
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Jeengar, Pooja, and Madhubala Chauhan. "Association of metabolic syndrome in polycystic ovarian syndrome." New Indian Journal of OBGYN 3, no. 2 (January 2017): 90–94. http://dx.doi.org/10.21276/obgyn.2017.3.2.5.

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3

Alcalay, M., D. Bider, S. Lipitz, S. Mashiach, D. Levran, and J. Dor. "Polycystic ovarian syndrome." Gynecological Endocrinology 9, no. 2 (January 1995): 119–23. http://dx.doi.org/10.3109/09513599509160200.

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4

Madnani, Nina, Kaleem Khan, Phulrenu Chauhan, and Girish Parmar. "Polycystic ovarian syndrome." Indian Journal of Dermatology, Venereology, and Leprology 79, no. 3 (2013): 310. http://dx.doi.org/10.4103/0378-6323.110759.

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5

SHUKAR-UD-DIN, SHAZIA, SADAF AHMED ASIM, SYEDA RABIA, Rumina Tabassum, and Aisha Razzaque. "POLYCYSTIC OVARIAN SYNDROME;." Professional Medical Journal 20, no. 05 (October 15, 2013): 719–25. http://dx.doi.org/10.29309/tpmj/2013.20.05.1208.

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Background: Polycystic ovarian syndrome is a common disease among the women in reproductive age group and morecommon in South Asian women. Clinical presentations include menstrual disorders, subfertility, obesity,hirsutism, acne vulgaris andacanthosis. Objectives: The objective of study was to investigate co relation between acne and polycystic ovaries and its relation tomenstrual irregularity. Methodology: A total of 56women were enrolled in the study from Outpatient Department of Obs&Gynae andDermatology, Dow University Hosptial, Ojha campus by convenient sampling. It was cross sectional study, conducted from July 2012 toNovember 2012.Verbal consent was taken. Sociodemographic information,Anthropometric measurement (height, weight, BMI) andacne severity with affected area, menstrual irregularities were administered on pre designed questionnaire.Pelvic ultrasound forpolycystic ovaries and serum LH, FSH in follicular phase of menstrual cycle (2nd day) advised from Dow Radiology and Dow Labrespectively. Results: A total of56 patients of PCOS were enrolled during five month period. The mean age of patient was 21.1+_SD0.994. Frequency of acne was 32 (57.1%).The mean BMI was 19.66 +_SD 4.54. Face was the commonest area involved in 24 (42.9%).menstrual irregularity was found in 50 (89.4%) women. There was no statistically significant relation seen between acne andoligomenorrhea. (X2 = 0.55 , P = 0.45). It was also determined that there was no co relation seen between the acne and serumtestosterone level calculated by independent sample t test.(P = 0.17) but statistically significant association seen between severity ofacne and serum LH/FSH ratio. (t test =3.28, p= 0.004) Conclusion: Acne was found in 32 (57.1%) women with PCOS. The study resultsrevealed a significant association seen between severity of acne and serum LH/FSH ratio. Relation between acne and serum testosteronelevel was statistically insignificant.
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BUTT, KIRAN, FARAH DEEBA, and HAVAIDA ATTIQUE. "POLYCYSTIC OVARIAN SYNDROME;." Professional Medical Journal 19, no. 06 (November 5, 2012): 786–88. http://dx.doi.org/10.29309/tpmj/2012.19.06.2483.

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Objective: The objective of the present study was to determine the changes in the glucose level and lipid profile in patients withpolycystic ovarian syndrome (PCOS). Study Design: Descriptive study. Place and Duration of the study: This study was conducted atInstitute of Molecular Biology and Biotechnology, The University of Lahore from June 2009 to June 2010. Patients and Methods: Total 50patients with PCOS were included and 50 age-matched control subjects were also selected for comparison. Their glucose levels and lipidprofile were assessed using commercial kits. The data thus obtained was subjected to statistical analysis. Results: Significant differences(P<0.05) in fasting blood glucose level and individual parameters of lipid profile were observed in women with PCOS. A higher prevalence ofhypertriglyceridemia, hypercholesterolemia, higher LDL, lower HDL and higher fasting blood glucose levels was explored in PCOS womenthan controls. Conclusions: Abnormal glucose level and lipid profile in PCOS women showed that these women are at an increased risk ofdeveloping diabetes and subsequently cardiovascular diseases.
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7

Yasin, Misbah, and Fouzia Yasmeen. "POLYCYSTIC OVARIAN SYNDROME." Professional Medical Journal 21, no. 01 (December 5, 2018): 179–84. http://dx.doi.org/10.29309/tpmj/2014.21.01.1918.

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Objectives: The objective of this study is to: describe the pattern of disease inpatients with polycystic ovarian syndrome. Data Source: Medline Data Base. Design Of Study:Descriptive case series study. Settings: Gynaecological Outpatient Department of Ghurki trustteaching hospital Lahore. Duration: 6months period, from 8th October 2012 to 7th April 2013.Materials & Methods: Sixty cases of polycystic ovarian syndrome as diagnosed on ultrasoundwere selected. These cases were examined for height, weight, body mass index, hirsutism, acne,acnthosis nigricans, breast examination (galactorrhoea). These cases were investigated forblood sugar (random), Fasting Insulin, pelvic ultrasound, LH, FSH and serum prolactin. Results:The mean age of the patients were 24.93±5.67 years. There were 28 (47%) patients of menstrualdisturbance, 18 (30%) patients of subfertility, 9 (13%) of obesity. There were 13 (21.7%) patients2of BMI level of equal to or less than 25 kg/m and 47 (78.3%) patients of BMI level more than 252kg/m . There were 25 (41.7%) patients of hirsuitim, 14 (23.3%) patients of acne and 17 (28.3%)patients of acanthoris nigricans on physical examination. There were 28 (46.7%) patients of LHlevel of more than 10 IU/L (raised) and 1 (1.7%) patient of more than 350 mU/L prolactin (raised).The mean right ovary volume of the patients was 12.08±3.04 and mean left ovarian volume of thepatients was 11.86±4.83. Conclusions: Hirsutism and cycle disturbances are the major clinicalfeatures of polycystic ovarian syndrome patients. Obesity seems to be more prevalent inpolycystic ovarian syndrome patients. The ratio between LH and FSH as a diagnostic tool waslow in our patients.
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8

Saleem, Shemaila, Fauzia Hanif, and Amanat Ali. "POLYCYSTIC OVARIAN SYNDROME;." Professional Medical Journal 24, no. 06 (June 5, 2017): 834–38. http://dx.doi.org/10.29309/tpmj/2017.24.06.1196.

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Background: Numerous ailments encompassing endometriosis, infertility andpolycystic ovarian syndrome (PCOS) are associated with Vitamin D deficiency. It is due to theexpression of vitamin D receptors in various tissues other than skeleton. Objectives: The currentstudy was conducted to compare the levels of vitamin D with body mass index in women withPCOS and healthy females of Rawalpindi. Study Design: Descriptive cross-sectional study.Period: 6 months. Setting: Research work was done at Railway Hospital (Gynecology andObstetrics Department), Rawalpindi in alliance with Islamic International Medical College,Rawalpindi. Materials and methods: A sample of 50 apparently healthy women and 100cases of polycystic ovarian syndrome in their reproductive age (15-45 years) were selectedafter diagnosis by the clinician. Data was assembled by using a pre-structured questionnaire.Data analysis was carried out using SPSS version 21. Results: Our results show that the bodymass index in patients with polycystic ovarian syndrome (27.094+4.369) was considerably(p-value < 0.05) more in contrast to the healthy controls (20.739+3.452) but no significant(p-value >0.05) difference was observed between vitamin D levels across a range of Bodymass indices among the controls and cases. Conclusion: No significant association betweenBMI and vitamin D status was found in healthy as well as PCO women.
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9

Harding, Emma. "Polycystic Ovarian Syndrome." InnovAiT: Education and inspiration for general practice 3, no. 2 (January 16, 2010): 71–75. http://dx.doi.org/10.1093/innovait/inp124.

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10

Abell, Sue, and John L. Ey. "Polycystic Ovarian Syndrome." Clinical Pediatrics 47, no. 9 (July 14, 2008): 969–70. http://dx.doi.org/10.1177/0009922807303932.

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11

Kelley, Larry S. "Polycystic Ovarian Syndrome." AAOHN Journal 51, no. 1 (January 2003): 23–27. http://dx.doi.org/10.1177/216507990305100107.

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12

Khan, Khurshid A., Sameer Stas, and L. Romayne Kurukulasuriya. "Polycystic Ovarian Syndrome." Journal of the CardioMetabolic Syndrome 1, no. 2 (March 2006): 125–32. http://dx.doi.org/10.1111/j.1559-4564.2006.05675.x.

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13

Ruby, Laura A. "Polycystic Ovarian Syndrome." Journal for Nurse Practitioners 4, no. 9 (October 2008): 697–704. http://dx.doi.org/10.1016/j.nurpra.2008.08.005.

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14

Trikudanathan, Subbulaxmi. "Polycystic Ovarian Syndrome." Medical Clinics of North America 99, no. 1 (January 2015): 221–35. http://dx.doi.org/10.1016/j.mcna.2014.09.003.

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15

Mishra, S., and A. Shrestha. "Polycystic Ovarian Syndrome." Journal of Universal College of Medical Sciences 1, no. 1 (August 10, 2013): 39–41. http://dx.doi.org/10.3126/jucms.v1i1.8423.

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16

Boqun, Xu, Dai Xiaonan, Cui YuGui, Gao Lingling, Dai Xue, Chao Gao, Diao Feiyang, et al. "Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome." International Journal of Endocrinology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/367956.

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Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries.Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and surgical treatment with the signed consent form. The cellular localization of SET protein was observed by immunohistochemistry. The expression levels of SET protein were analyzed by Western Blot.Result. SET protein was expressed predominantly in the theca cells and oocytes of human ovarian follicles in both PCOS ovarian tissues and normal ovarian tissues. The level of SET protein expression in polycystic ovaries was triple higher than that in normal ovaries(P<0.05).Conclusion. SET was overexpressed in polycystic ovaries more than that in normal ovaries. Combined with its localization in theca cells, SET may participate in regulating ovarian androgen biosynthesis and the pathophysiology of hyperandrogenism in PCOS.
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17

Muhammad, Bakhtyar Kamal. "Characteristics and Risk Factors for Polycystic Ovarian Syndrome Among Females." Kurdistan Journal of Applied Research 5, no. 1 (June 30, 2020): 200–209. http://dx.doi.org/10.24017/science.2020.1.14.

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Polycystic ovary syndrome (PCOS) is a major endocrinal syndrome may affect the female at adult ages. In polycystic ovary, the ovarian seen that are enlarged and the investigation may base on ultra-sonographic detection. Polycystic ovarian syndrome always represents a spectrum of syndrome rather than the diseases. Also clinically presented by polycystic on ovarian and generally demonstrated by reversible. 104 female patients were examined, 18 (17.3%) of females were diagnosed with polycystic ovarian syndrome. The mean age was 24.62 ± 7.32 years (ranged from 15 month to 50 years-old). 17 (94.4%) of women were less than 25 years-old p-value=0.03, hormonal abnormality was the most frequent symptoms in relation to polycystic ovarian syndrome 10 (55.5%) and p-value=0.001. 16 (88.9%) of women experienced vaginal discharge p-value=0.09. In conclusion, one from six females is expected to experience polycystic ovarian syndrome. Young females are probably to be at a high risk for developing polycystic ovarian syndrome. Despite uncertain etiology of polycystic ovarian syndrome, marital status, stress or anxiety, doing a regular exercise and pregnancy are all related parameters to the incidence of polycystic ovarian syndrome. Additionally, Cases with high hormonal abnormality and vaginal excretion could be considerable indicators of polycystic ovarian syndrome.
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Muhammad, Bakhtyar Kamal. "Characteristics and Risk Factors for Polycystic Ovarian Syndrome Among Females." Kurdistan Journal of Applied Research 5, no. 1 (June 30, 2020): 200–209. http://dx.doi.org/10.24017/science.2020.14.

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Polycystic ovary syndrome (PCOS) is a major endocrinal syndrome may affect the female at adult ages. In polycystic ovary, the ovarian seen that are enlarged and the investigation may base on ultra-sonographic detection. Polycystic ovarian syndrome always represents a spectrum of syndrome rather than the diseases. Also clinically presented by polycystic on ovarian and generally demonstrated by reversible. 104 female patients were examined, 18 (17.3%) of females were diagnosed with polycystic ovarian syndrome. The mean age was 24.62 ± 7.32 years (ranged from 15 month to 50 years-old). 17 (94.4%) of women were less than 25 years-old p-value=0.03, hormonal abnormality was the most frequent symptoms in relation to polycystic ovarian syndrome 10 (55.5%) and p-value=0.001. 16 (88.9%) of women experienced vaginal discharge p-value=0.09. In conclusion, one from six females is expected to experience polycystic ovarian syndrome. Young females are probably to be at a high risk for developing polycystic ovarian syndrome. Despite uncertain etiology of polycystic ovarian syndrome, marital status, stress or anxiety, doing a regular exercise and pregnancy are all related parameters to the incidence of polycystic ovarian syndrome. Additionally, Cases with high hormonal abnormality and vaginal excretion could be considerable indicators of polycystic ovarian syndrome.
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Siddharth Bharatbhai, Rajpura, and Desai Archish Ishvarbhai. "Metabolic Syndrome among Polycystic Ovarian Syndrome: A Cross Sectional Study." Indian Journal of Obstetrics and Gynecology 7, no. 1 (2019): 65–71. http://dx.doi.org/10.21088/ijog.2321.1636.7119.12.

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20

Tanvir, Seema. "Polycystic Ovarian Syndrome: A Syndrome Entailing early Diagnosis and Treatment." International Journal of Nursing & Midwifery Research 05, no. 03 (October 31, 2018): 81–85. http://dx.doi.org/10.24321/2455.9318.201837.

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Di Pietro, Mariana, Natalia Pascuali, Fernanda Parborell, and Dalhia Abramovich. "Ovarian angiogenesis in polycystic ovary syndrome." Reproduction 155, no. 5 (May 2018): R199—R209. http://dx.doi.org/10.1530/rep-17-0597.

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Polycystic ovary syndrome (PCOS) is the most prevalent endocrine pathology among women in reproductive age. Its main symptoms are oligo or amenorrhea, hyperandrogenism and the presence of ovarian cysts. It is also associated with infertility, obesity and insulin resistance. Mainly due to its heterogeneity, PCOS treatments are directed to manage its symptoms and to prevent associated diseases. The correct formation and regression of blood vessels during each ovarian cycle is indispensable for proper follicular development, ovulation and corpus luteum formation. The importance of these processes opened a new and promising field: ovarian angiogenesis. Vascular alterations characterize numerous pathologies, either with increased, decreased or abnormal angiogenesis. In the last years, several anomalies of ovarian angiogenesis have been described in women with PCOS. Therefore, it has been suggested that these alterations may be associated with the decreased – or lack of – ovulation rates and for the formation of cysts in the PCOS ovaries. Restoration of a proper vessel formation in the ovaries may lead to improved follicular development and ovulation in these patients. In the present review, we attempt to summarize the alterations in ovarian angiogenesis that have been described in women with PCOS. We also discuss the therapeutic approaches aimed to correct these alterations and their beneficial effects on the treatment of infertility in PCOS.
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J, Ramzi. "Evaluation of Biochemical Parameters in Polycystic Ovarian Syndrome." Journal of Medical Science And clinical Research 05, no. 03 (March 19, 2017): 19078–83. http://dx.doi.org/10.18535/jmscr/v5i3.124.

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MD, Dr Anupama Singh,. "Study of Cutaneous Manifestations of Polycystic Ovarian Syndrome." Journal of Medical Science And clinical Research 05, no. 04 (April 30, 2017): 21177–82. http://dx.doi.org/10.18535/jmscr/v5i4.228.

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Al Ghazali, Basima Shamkhi, and Sara Monther. "Serum Mannose Level and Its Association in Women with Polycystic Ovarian Syndrome: a Case Control Study of Al-Najaf City / 2020." Kufa Medical Journal 18, no. 1 (May 22, 2022): 1–10. http://dx.doi.org/10.36330/kmj.v18i1.3273.

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Background: Polycystic ovarian syndrome is a common public health issue around the world. Insulin resistance and glucose intolerance play important role in the etiology of polycystic ovarian syndrome and the serum mannose is incorporated in metabolism of glucose. Aim of study: Determination of the association between serum mannose level and polycystic ovarian syndrome. Patients and Methods: A case control study enrolled eighty eight women were divided as forty four women with polycystic ovarian syndrome and forty four women without polycystic ovarian syndrome presented to outpatient clinic at Fertility Center/Al Sader Medical City and outpatient clinic of Al- Zahraa Teaching Hospital in Najaf city-Iraq during the period from 1st of February till 31st of December, 2020. Results: The mean Serum Mannose level of women with polycystic ovarian syndrome 7.37 was significantly higher than mean serum mannose of controls 1.32 (p<0.001). Cutoff serum mannose level of 1.98 had acceptable validity results (90.9% sensitivity, 90.9% specificity, 94% PPV, 90.5% NPV and 90% accuracy). The means of serum level testosterone and luteinizing hormones were significantly higher among women with polycystic ovarian syndrome, while mean follicular stimulating hormone level was significantly lower among women with polycystic ovarian syndrome. Conclusions: The serum mannose level is significantly increased in women with polycystic ovarian syndrome which may indicate its possible role in the pathophysiology of polycystic ovarian syndrome.
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Azizova, M. E. "Polycystic ovary syndrome - modern concepts." Kazan medical journal 96, no. 1 (February 15, 2015): 77–80. http://dx.doi.org/10.17750/kmj2015-077.

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The article reviews current concepts of etiology and pathogenesis of polycystic ovary syndrome. Currently, numerous forms of the syndrome, manifesting by a variety of clinical, morphologic signs and features of endocrine profile, exist. It was revealed that polycystic ovary syndrome is a multifactorial, genetically determined disease. Laboratory diagnosis in females with polycystic ovary syndrome is based on measuring concentrations of hormones. Results of ovarian sonography are of a great importance, allowing to diagnose polycystic ovary syndrome. Another method of instrumental diagnosis is laparoscopy, revealing two-sided growth ovarian hypertrophy and multiple subcapsular cysts. Ovarian capsule looks thickened, smooth, with a marked vascular pattern. Treatment depends on the clinical features and intensity of symptoms, as well as on patient’s interest in pregnancy. The choice of treatment options should be supported by clinical and laboratory data, considering pathogenetic type of the disease. The treatment of polycystic ovary syndrome includes conservative and surgical approaches. The main targets of drug treatment is the cessation of clinical and metabolic symptoms of the disease, decreasing the symptoms of virilescence, restoring the menstrual cycle and ovulation induction. Indication for surgical treatment is non-efficiency of drug treatment in restoring fertility. Thereby, multiple factors determining clinical symptoms and morphologic changes in ovaries, including central mechanisms of pituitary gland gonadotropic function, local ovarian factors, extraovarial endocrine and metabolic disorders, participate in pathogenesis of polycystic ovary syndrome. The early initiation of treatment in patients with polycystic ovary syndrome may preserve the fertility, as well as prevent hyper- and neoplastic diseases of endothelium, and the syndrome’s late complications.
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Gavali, Dr Urmila, Dr Mayuri Pawar, Dr Gautam Aher, and Dr Suhas Shinde. "Clinical Profile of Polycystic Ovarian Syndrome Patients In Tertiary Care Hospital." VIMS Health Science Journal 8, no. 3 (September 25, 2021): 99–103. http://dx.doi.org/10.46858/vimshsj.8303.

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ABSTRACT: Background: Polycystic ovarian syndrome (PCOS)is common gynecological endocrinopathy characterized by chronic anovulation and hyperandrogenism affecting 5-10% of women worldwide. It is a heterogenous, multifactorial, complex genetic disorder with uncertain etiology and is one of the most common treatable cause of infertility. AIM: To study the various clinical presentations in polycystic ovarian syndrome. MATERIALS AND METHODS: Present study is cross sectional observational study carried out in tertiary care centre. This study was performed in the Out Patient Department of Obstetrics and Gynecology. RESULTS: The mean age of 41 patients in the study was 23.6 years. Most common presenting symptom in patients is menstrual irregularities (89%) followed by infertility and hirsutism. USG (abdo+pelvis) showing polycystic ovarian syndrome ovaries. Around 39% patients with PCOS developed insulin resistance. KEYWORDS: - Amenorrhea, Infertility, Oligomenorrhea, Polycystic Ovarian Syndrome.
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Gavali, Dr Urmila, Dr Mayuri Pawar, Dr Gautam Aher, and Dr Suhas Shinde. "Clinical Profile of Polycystic Ovarian Syndrome Patients In Tertiary Care Hospital." VIMS Health Science Journal 8, no. 3 (September 25, 2021): 99–103. http://dx.doi.org/10.46858/vimshsj.8303.

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ABSTRACT: Background: Polycystic ovarian syndrome (PCOS)is common gynecological endocrinopathy characterized by chronic anovulation and hyperandrogenism affecting 5-10% of women worldwide. It is a heterogenous, multifactorial, complex genetic disorder with uncertain etiology and is one of the most common treatable cause of infertility. AIM: To study the various clinical presentations in polycystic ovarian syndrome. MATERIALS AND METHODS: Present study is cross sectional observational study carried out in tertiary care centre. This study was performed in the Out Patient Department of Obstetrics and Gynecology. RESULTS: The mean age of 41 patients in the study was 23.6 years. Most common presenting symptom in patients is menstrual irregularities (89%) followed by infertility and hirsutism. USG (abdo+pelvis) showing polycystic ovarian syndrome ovaries. Around 39% patients with PCOS developed insulin resistance. KEYWORDS: - Amenorrhea, Infertility, Oligomenorrhea, Polycystic Ovarian Syndrome.
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MUNSON, BECKY LIEN. "… About polycystic ovarian syndrome." Nursing 32, no. 11 (November 2002): 78. http://dx.doi.org/10.1097/00152193-200211000-00053.

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Edmondson, Emily S. "Understanding Polycystic Ovarian Syndrome." Physician Assistant Clinics 3, no. 3 (July 2018): 353–62. http://dx.doi.org/10.1016/j.cpha.2018.02.004.

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Ságodi, László, Ildikó Schmidt, Ildikó Vámosi, and László Barkai. "Peripubertal ovarian cyst torsion as an early complication of undiagnosed polycystic ovarian syndrome." Orvosi Hetilap 154, no. 3 (January 2013): 113–17. http://dx.doi.org/10.1556/oh.2013.29520.

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The aim of the authors is to present two cases which raise the possibility of an association between polycystic ovarian syndrome/hyperandrogenism and ovarian cyst torsion in peripubertal girls. Androgen excess may cause more frequently ovarian cyst formation in premenarcheal or young adolescents with undiagnosed polycystic ovarian syndrome than in adults. The authors recommend that polycystic ovarian syndrome as wel as late onset congenital adrenal hyperplasia should be considered in peripubertal adolescents with ovarian cyst torsion. In case polycystic ovarian syndrome is confirmed, adequate management according to age and pubertal development of the patients should be commenced. Orv. Hetil., 2013, 154, 113–117.
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Bahadori, Atekeh, Afrouz Khazamipour, and Dariush D.Farhud. "Genetics Poly Cystic Ovary Syndrome." Asian Pacific Journal of Cancer Biology 1, no. 4 (December 28, 2016): 97–105. http://dx.doi.org/10.31557/apjcb.2016.1.4.97-105.

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Background: Polycystic ovarian syndrome is a complicated hereditary disorder which does not have specific reason and 6-10% of women at fertility age are involved. In other word we can say that this syndrome is a familial hereditary syndrome which developed with combination of environmental and genetic factors. Polycystic ovarian syndrome (PCOS) is related to cardiovascular diseases and has psychological and neurological effects on life quality as well as uterine and breast cancers. The main criteria for diagnosis of polycystic ovarian syndrome are chronic anovulation and hyperandogenism and the sub-criteria are insulin resistance, hirsutism and obesity onset at menarche age, anovulation alternatively is associated with increased testosterone level and DHEA-S. The cause of polycystic ovarian syndrome (PCO) is unknown, but it could be the result of complex genetic factors which are evident at puberty onset, also hereditary and non-hereditary factors could be the cause of polycystic ovarian syndrome (PCO) pheno ype. In many women with polycystic ovarian syndrome, the insulin level is high. It seems that high levels of insulin increase androgens production. High levels of androgens can cause acne, supernumerary hair growth, weight gain, and ovulation problem.Conclusion: Early diagnosis and treatment of polycystic ovarian syndrome could help to reduce long-term complications such as diabetes type II, high blood pressure, heart disease and stroke.
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Saroja, Banothu. "Laparoscopic Ovarian Drilling in Clomiphene Citrate Resistant Cases of Polycystic Ovarian Syndrome." Indian Journal of Obstetrics and Gynecology 7, no. 3 (P-2) (2019): 471–74. http://dx.doi.org/10.21088/ijog.2321.1636.7319.17.

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Okanovic, Milana, and Olga Zivanovic. "Valproate, bipolar disorder and polycystic ovarian syndrome." Medical review 69, no. 3-4 (2016): 121–26. http://dx.doi.org/10.2298/mpns1604121o.

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Introduction. Polycystic ovarian syndrome is a syndrome of ovarian dysfunction with the principal features of hyperandrogenism and polycystic ovary morphology. A large number of studies conducted on this topic have suggested a possible role of anticonvulsants, particularly valproate, in the pathogenesis or risk factors associated with polycystic ovarian syndrome. Bipolar treatment guidelines from Canada and the United States of America recommend valproate as the first line strategy in the acute treatment of bipolar disorder. Discussion. Most persons with bipolar disorder require maintenance treatment. Long-term administration of valproate in women with bipolar disorder or epilepsy is believed to result in the increased risk of hyperandro?genism, menstrual abnormalities and polycystic ovaries. Valproate may also increase the risk of infertility and other associated symptoms of polycystic ovarian syndrome. Therefore, particular caution is indicated in the use of valproate in women of reproductive age. Conclusion. The treatment of the female patients with bipolar disorder presents various challenges for the clinician. Every woman of reproductive age needs to know the risk and benefits of her pharmacologic treatment options. Bipolar disorder should be considered chronic disorder, whose development is largely affected by hormonal changes and reproductive cycle in women. These issues should be researched more thoroughly in order to opt for the most appropriate treatment in women with bipolar disorder.
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Manappallil, Robin George, Sivadas Vilakupadath Kokoori, and Nandini Valsala. "Severe Ovarian Hyperstimulation Syndrome despite low dose stimulation in Polycystic Ovarian Syndrome." Asian Journal of Medical Sciences 10, no. 3 (May 1, 2019): 50–53. http://dx.doi.org/10.3126/ajms.v10i3.22728.

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Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic complication of assisted reproduction technology. There is cystic enlargement of the ovaries along with fluid shift from the intravascular compartment to the third space due to increased capillary permeability and ovarian neoangiogenesis. Severe OHSS is uncommon and the condition can be fatal. Low-dose gonadotropin protocols have been introduced to reduce the risk of OHSS in patients with polycystic ovary syndrome (PCOS). The patient being reported had PCOS and developed severe OHSS despite low dose gonadotropin stimulation; which is a rare scenario.
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Sridhar, M., and Chillamherla Susmitha. "Laparoscopic ovarian drilling in clomiphene citrate resistant polycystic ovarian syndrome patients." International Surgery Journal 5, no. 10 (September 25, 2018): 3230. http://dx.doi.org/10.18203/2349-2902.isj20183846.

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Background: Polycystic ovarian disease (PCOD) or polycystic ovarian syndrome (PCOS) is a common endocrine disorder which commonly affects women in their reproductive age, often leading to anovulatory infertility. There has been a resurgence of surgical intervention with the advent of ovarian drilling. This study was performed to assess the surgical management for patients with PCOS resistant to hormonal therapy.Methods: A thorough history and demographic details were taken from all the patients. A detailed clinical examination, along with transvaginal sonography was done. Laparoscopic ovarian drilling was performed on the patients under general anesthesia.Results: Most of the women were in the 3rd decade of their life and majority of the women had attained menarche at 13 years. The chief complaint of the patients was irregular periods experienced by 80%. 44.4% of the patents had normal BMI, while 31.5% were underweight. Most of the patients (6.7%) showed no evidence of hyperandrogenism, while 20% had hirsutism, 11% had acne.Conclusions: Polycystic ovarian syndrome is quite prevalent among the women of reproductive age. The effective treatment for PCOS which are resistant to hormonal therapy is laparoscopic drilling of the ovaries which results in ovarian function.
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Игумнов, Илья, Ilya Igumnov, Михаил Кузьмин, Mikhail Kuzmin, Лариса Сутурина, and Larisa Suturina. "POLYCYSTIC OVARY SYNDROME AND PERIODONTAL STATUS: A LITERATURE REVIEW." Acta biomedica scientifica 2, no. 5 (January 18, 2018): 137–40. http://dx.doi.org/10.12737/article_5a3a0ea8f21cb2.52424909.

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The review considers the problem of connection the polycystic ovarian syndrome and periodontal disorders of the fertile women. The authors marked that this problem is not virtually touched upon in Russian science. In the foreign literature this issue is discussed in connection with studying the micro-biome and oxidative stress. The authors refer to some articles showing that the quantity of pathogenic microorganisms responsible for periodontal disorders and the level of specific antibodies in blood serum are increased in women with polycystic ovarian syndrome, especially in the cases of gum inflammation. Also the article gives the data where the results show the wider spreading of periodontal disorders in women with polycystic ovarian syndrome in comparison with the healthy ones where controls were matched by age and BMI. The authors think that studies on oral microbiocenose disorders and tissue quality of periodontium of the fertile women with polycystic ovarian syndrome are quite important. The further studying of connection of polycystic ovarian syndrome and oral mucous membrane inflammation could reveal definite periodontal pathogens, which can influence systematic inflammation processes in polycystic ovarian syndrome.
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Bilal, Muhammad, Syeda Khadija, Nosheen Arshad, and Sana Saleem. "Among The Largest Population Which Age Group is the Most Having Polycystic Ovarian Syndrome." Saudi Journal of Medicine 7, no. 1 (January 17, 2022): 42–44. http://dx.doi.org/10.36348/sjm.2022.v07i01.007.

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Background: Polycystic Ovarian Syndrome (PCO), also called Hyper androgenic anovulation (HA), or Stein-Leventhal syndrome is a very common disorder of ovaries that only occurs in females mainly of reproductive age of 4% to 20% approximately. It is a condition in which multiple cysts, almost 9 to 10 are noted in the ovary, can be on one side or both sides and the volume of the ovary exceeds 10ml. The common representation of PCOS includes obesity, acne, hirsutism, and complications in pregnancy. Objective: To evaluate among the largest population which age group is the most having polycystic ovarian syndrome. Methodology: A literature search was performed with the use of search engines. The search engines that provided the articles for systemic review are Google Scholar, MDPI, PubMed, Medscape, and NCBI. For article searching following keywords were used: Polycystic ovaries, reproductive age changes, and age group. Conclusion: It is concluded that there is a specific age that has Polycystic syndrome ranging from 12-25.
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Ashraf, Nadia ,., Aasma Hanif, Saima Rafique, Maria Ashfaq, and Memoona Faiyaz. "Diagnostic Evaluation of Polycystic Ovarian Disease." Pakistan Journal of Medical and Health Sciences 16, no. 3 (March 26, 2022): 356–58. http://dx.doi.org/10.53350/pjmhs22163356.

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Background: Polycystic ovary syndrome is a heterogeneous endocrine disorder that affects about one in 15 females worldwide. The major endocrine disruption is excessive androgen secretion or activity, and a large proportion of women also have abnormal insulin activity. Many body systems are affected, resulting in several health complications, including menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome. Several biochemical tests play an important role in diagnosing and predicting health consequences of this disease. Aims: To determine the signs and symptoms of polycystic ovarian syndrome in gynaecology outpatient department of Jinnah Hospital Lahore and to describe the clinical presentations, biochemical findings and ultrasound findings in patients with polycystic ovarian syndrome. Design Descriptive case series Setting: Department of Obstetrics & Gynecology, Jinnah Hospital Lahore from 1st March 2018 to 28th February 2019. Methodology: One hundred patients of reproductive age group with signs and symptoms of polycystic ovarian syndrome were included. A detailed history and examination was carried out. Then diagnosis of polycystic ovarian syndrome was confirmed by laboratory tests and ultrasound findings. Results: 72% patients presented with menstrual irregularities.56% patients had BMI> 25kg/m2 .72% patients had hirsutism. Out of total patients 62% patients were married and 38% were unmarried. Among those who were married 24(38.7%) patients presented with primary infertility and 17(27.4%) presented with secondary infertility.44% patients had raised total serum testosterone. Diabetes mellitus was present in 14% of patients. Ultrasound criteria were fulfilled in 77% patients with polycystic ovarian disease. Conclusion: Most common clinical presentations of polycystic ovarian disease were found to be menstrual irregularities, hirsutism and obesity. Hyperinsulinemia and hyperandrogenism was also more commonly found in obese XIV and hirsute women. Also ultrasound is a very useful diagnostic tool for polycystic ovarian disease. Keywords: Polycystic ovarian disease, diagnostic evaluation, health consequences, diabetes mellitus, insulin resistance.
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Nikolayenkov, Igor Pavlovich, Vladimir Vsevolodovich Potin, Marina Anatolyevna Tarasova, Natalya Nikolayevna Tkachenko, Maria Igorevna Yarmolinskaya, Yekaterina Mikhaylovna Timofeyeva, and Yanina Andreyevna Samoylovich. "Ovarian aromatase activity in polycystic ovarian syndrome." Journal of obstetrics and women's diseases 63, no. 1 (December 15, 2014): 10–16. http://dx.doi.org/10.17816/jowd63110-16.

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41 women with polycystic ovary syndrome (PCOS) and 15 healthy women of reproductive age were examined to evaluate ovarian aromatase activity. Aromatase activity was determined by the decrease of estradiol level after peroral intake of aromatase inhibitor letrosol. To examine aromatase activity of antral follicle (∆E2) was divided on the blood level of antimullerian hormone (AMH), which is corresponded to the number of antral follicles. Significant variations of aromatase activity of antral follicles in patients with PCOS were determined: in 34.1 % of women it was within physiological ranges, in 48.8 % of women it was decreased and in 17.1 % of women it was increased. Aromatase activity of antral follicles in patients with PCOS correlated with blood levels of estradiol (r = 0.67), estron (r = 0.27), free testosterone(r = 0.43), androstendion (r = 0.34) and body mass index (r = 0.30). Aromatase activity had reverse correlation with number of antral follicles. Athors suggest that the sensitivity of the ovaries to gonadotropinic stimulation is decreased in patients with PCOS and low aromatase activity.
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Mohammed Saleh, Nishtiman, and Yousif Baha`addin Ahmed. "Prevalence of cardiovascular risk factors among patients with polycystic ovarian syndrome (PCOS) in Erbil city." Diyala Journal of Medicine 21, no. 1 (October 25, 2021): 55–63. http://dx.doi.org/10.26505/djm.21015950308.

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Background: Polycystic ovarian syndrome is a common endocrine disorder of women during reproductive age, associated with increased risk of cardiometabolic diseases. Objective: To assess the prevalence of cardiovascular risk factors in patients with the polycystic ovarian syndrome in comparison to age-matched control. Patients and Methods: This cross-sectional studyis conducted in Erbil city fromSeptember 2020 to January 2021. It included 40 cases of polycystic ovarian syndrome and 40 cases of healthy controls. Participants underwent detailed history, physical examination. Laboratory investigations (blood sugar, lipid profile, serum testosterone and serum prolactin) and pelvic ultrasound were done for them. Data analysis was performed by Statistical Package for Social Sciences (SPSS) version 25. Results: Women with the polycystic ovarian syndrome have a higher proportion to obesity, abnormal blood sugar, and dyslipidemia, they have higher rate of menstrual irregularity, hyperandrogenic state and hirsutism, than age-matched control. The risk for hypertension remains the same for both PCOS and the control group. Conclusion: The proportion of obesity, diabetes, and dyslipidemia is higher in Polycystic ovarian syndrome than the control group. Keywords: Polycystic ovarian syndrome, obesity, diabetes mellitus, heart disease
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Galagali, Preeti Manmohan. "Polycystic ovarian syndrome in adolescence." Karnataka Pediatric Journal 35 (January 25, 2021): 95–99. http://dx.doi.org/10.25259/kpj_29_2020.

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Polycystic ovarian syndrome (PCOS) may clinically manifest for the 1st time in adolescence. Hyperandrogenemia and oligo-anovulation are the two essential criteria for the diagnosis of PCOS. PCOS has long-term effects on cardiovascular, endocrinal, reproductive, and metabolic health. Early management of PCOS mitigates its long-term effects on health. Therapeutic lifestyle management and psychological counseling form the main stay of treatment in adolescence. Diagnosis of PCOS in adolescence is revisited and confirmed in adulthood. Management of PCOS is multidisciplinary and requires long-term regular follow-up in adolescence and adulthood.
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Madnani, Nina, Kaleem Khan, Phulrenu Chauhan, and Parmar. "Polycystic ovarian syndrome: A review." Indian Journal of Dermatology, Venereology, and Leprology 80, no. 2 (2014): 154. http://dx.doi.org/10.4103/0378-6323.129399.

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Garg, Ruchika, Kanthi Bansal, Pooja Sharma Dimri, and Apoorva Pallam Reddy. "Decoding Polycystic Ovarian Syndrome (PCOS)." Journal of South Asian Federation of Obstetrics and Gynaecology 13, no. 2 (2021): 147. http://dx.doi.org/10.5005/jsafog-13-2-147.

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44

Sundararajan, Jeyshree Krishnaswamy, Yanyan Li, and Ahmad Hadaegh. "Healthbot for Polycystic Ovarian Syndrome." International Journal of Database Management Systems 13, no. 2 (April 30, 2021): 1–08. http://dx.doi.org/10.5121/ijdms.2021.13201.

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Polycystic ovarian syndrome(PCOS) is one of the predominant hormonal imbalances present in women of reproductive age. It needs to be diagnosed and treated at an earlier stage as it's inter-related to diabetes, high cholesterol levels, and obesity. This paper presents an application specially designed for women to help them keep track of their Body Mass Index, Blood Sugar, and Blood Pressure based on their age. The people diagnosed with PCOS(an endocrine disorder) can use this application to make their life easy since it helps follow certain exercises, diets, and timely reminders for water and medicines. It has features like the period tracker to track the user’s menstrual cycle, find dieticians nearby, links to various PCOS supplements, users can track their moods during different menstrual phases and control their mood swings. Finally, the application has games to add that interactive touch.
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Varughese, Asha K., and Veena Greetta Tauro. "Polycystic Ovarian Syndrome-An Overview." International Journal of Nursing Education and Research 7, no. 4 (2019): 601. http://dx.doi.org/10.5958/2454-2660.2019.00134.0.

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Shah, Disha, and Dr Shruti Bobade. "Polycystic Ovarian Syndrome and Autism." JOURNAL OF PSYCHOSOCIAL RESEARCH 13, no. 2 (January 25, 2019): 435–42. http://dx.doi.org/10.32381/jpr.2018.13.02.18.

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McElveen, Helen. "Clinical audit: polycystic ovarian syndrome." InnovAiT: Education and inspiration for general practice 6, no. 11 (September 27, 2013): 731–34. http://dx.doi.org/10.1177/1755738013495672.

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I., Popescu. "Controversies in polycystic ovarian syndrome." Gineco.eu 13, no. 1 (March 20, 2017): 42–45. http://dx.doi.org/10.18643/gieu.2017.42.

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Zacur, Howard, and Giraud Foster. "Hyperprolactinemia and Polycystic Ovarian Syndrome." Seminars in Reproductive Medicine 10, no. 03 (August 1992): 236–45. http://dx.doi.org/10.1055/s-2007-1018879.

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NAM MENKE, MARIE, and JEROME F. STRAUSS. "Genetics of Polycystic Ovarian Syndrome." Clinical Obstetrics and Gynecology 50, no. 1 (March 2007): 188–204. http://dx.doi.org/10.1097/grf.0b013e3180305f7c.

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