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Journal articles on the topic 'Polycystic ovary syndrome (PCOS)'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

Sosnova, Elena A. "Polycystic ovary syndrome." V.F.Snegirev Archives of Obstetrics and Gynecology 3, no. 3 (2016): 116–29. http://dx.doi.org/10.18821/2313-8726-2016-3-3-116-129.

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In the clinical lecture the polycystic ovary syndrome (PCOS) is considered as the multiple endocrine disease associated with the disturbed function of ovaries, pancreas, adrenalcortex, the hypothalamus and the pituitarygland. The attention is drawn at the modern look at PCOS as a “diagnosis of exclusion”. There is presented information on basic theories of pathogenesis and differential diagnosis of PCOS from other hyperandrogenic conditions. The ultrasound semiotics of polycystic ovaries is reported in details. There are considered opportunities and perspectives of various modalities of therap

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2

Aydın, Hatice Lamia, Batuhan Sarp Dayan, and Nur Dokuzeylül Güngör. "Polycystic ovary syndrome." Journal of Controversies in Obstetrics & Gynecology and Pediatrics 1, no. 3 (2023): 68–73. http://dx.doi.org/10.51271/jcogp-0015.

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Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting women of reproductive age. It is characterized by a combination of hormonal imbalances, ovarian dysfunction, and metabolic disturbances. PCOS has significant implications for women's health, fertility, and overall well-being. This comprehensive review aims to provide an overview of PCOS, including its etiology, clinical manifestations, diagnosis, and management strategies.

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Chavan, Miss Sanskruti S. "Review On: Polycystic Ovary Syndrome." International Journal for Research in Applied Science and Engineering Technology 13, no. 6 (2025): 1551–54. https://doi.org/10.22214/ijraset.2025.72370.

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A metabolic and reproductive condition affecting the ovaries is PCOD, often known as PCOS. An ovary is a dynamic organ that adapts to its hormonal environment by changing its shape, structure, and appearance. The primary cause of infertility, diabetes, and irregular menstruation is PCOD, also known as PCOS, a disorder in which women of reproductive age have enlarged ovaries that begin releasing an excessive quantity for male reproductive hormones (androgens). menstruation as well as hirsutism. Although the precise etiology of the condition is still unknown, it is thought to be brought on by ch

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Brakta, Soumia, Daria Lizneva, Kateryna Mykhalchenko, et al. "Perspectives on Polycystic Ovary Syndrome: Is Polycystic Ovary Syndrome Research Underfunded?" Journal of Clinical Endocrinology & Metabolism 102, no. 12 (2017): 4421–27. http://dx.doi.org/10.1210/jc.2017-01415.

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Abstract Context Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic abnormality with a worldwide prevalence of 4% to 21%, depending on diagnostic criteria. The National Institutes of Health (NIH) is the largest single funding agency in the world; it invests nearly $30.0 billion annually in biomedical research. Evidence Acquisition Using the NIH Research Portfolio Online Reporting tool, we searched for all grants awarded by the NIH for PCOS and three other disorders with similar degrees of morbidity and similar or lower mortality and prevalence [rheumatoid arthritis (RA), tubercul

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Umar, Mohammad Khan Siddqui Mohammad Fardeen* Thorat Dharmesh Jitendra Quazi Majaz Aejaz Ahmed. "Review Article On Polycystic Ovary Syndrome." International Journal in Pharmaceutical Sciences 2, no. 3 (2024): 147–54. https://doi.org/10.5281/zenodo.10781584.

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PCOS, also known as polycystic ovarian syndrome, is a prevalent infertility condition that impacts a noteworthy segment of the worldwide populations. With a prevalence of 8–13%, depending on the criteria applied and population investigated, it is the most frequent endocrinopathy affecting women of reproductive age and the primary cause of anovulatory infertility in women. Although polycystic ovaries have been described since 1721, Stein and Leventhal were the first to report the condition. Polycystic ovarian disease (PCOD) is the term used to describe the condition when polycystic ovarie

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6

Balen, Adam H. "Polycystic ovary syndrome (PCOS)." Obstetrician & Gynaecologist 19, no. 2 (2017): 119–29. http://dx.doi.org/10.1111/tog.12345.

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7

Dewailly, D., S. Hieronimus, P. Mirakian, and J. N. Hugues. "Polycystic ovary syndrome (PCOS)." Annales d'Endocrinologie 71, no. 1 (2010): 8–13. http://dx.doi.org/10.1016/j.ando.2009.12.003.

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8

Nasr, Ahmed. "Polycystic Ovary Syndrome (PCOS): Unraveling the Enigma." Open Access Journal of Gynecology 3, no. 3 (2018): 1–2. http://dx.doi.org/10.23880/oajg-16000165.

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Putri, Mentari Faisal, Haviz Yuad, and Andani Eka Putra. "Comparison Of Lactobacillus Plantarum, Lactobacillus Mucosae And Lactobacillus Farciminis Bacteria Between Polycystic Ovary Syndrome And Non Polycystic Ovary Syndrome Students At Medical Faculty Of Andalas University." Andalas Obstetrics And Gynecology Journal 8, no. 2 (2024): 732–45. http://dx.doi.org/10.25077/aoj.8.2.732-745.2024.

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Background: Polycystic Ovary Syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction, and morphological features of polycystic ovaries. It is associated with insulin resistance and hyperinsulinemia. Gut microbial dysbiosis plays a role in PCOS, which is associated with insulin resistance, hyperandrogenism, chronic inflammation, and metabolic syndrome. PCOS treatment with Probiotics maintains the stability and diversity of the gut microbiome. Objective: To determine the comparison of Lactobacillus plantarum, Lactobacillus mucosae, and Lactobacillus farciminis Bact

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Shailaja, K., Shruthi Ravindranathan, V. T. Jayanii, Aadhira Jinnah, and S. Shirly. "Polycystic Ovary Syndrome." Asian Journal of Pharmaceutical Research and Health Care 15, no. 4 (2023): 307–11. http://dx.doi.org/10.4103/ajprhc.ajprhc_68_23.

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ABSTRACT Polycystic ovary syndrome (PCOS) is a most common but complex, multifunctional, endocrine complaint that occurs substantially in women of reproductive age. It is characterized by irregularity or the absence of ovulation and elevated situations of androgen (hyperandrogenism) and insulin (hyperinsulinemia). It is a chronic condition that can lead to numerous successive and severe conditions such as uterine (endometrial) or ovarian carcinoma, diabetes mellitus, and cardiovascular diseases. The signs and symptoms of polycystic ovary disease may include irregular periods, infertility, weig

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Joham, Anju E., and Alexia S. Peña. "Polycystic Ovary Syndrome in Adolescence." Seminars in Reproductive Medicine 40, no. 01/02 (2022): e1-e8. http://dx.doi.org/10.1055/s-0042-1757138.

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AbstractPolycystic ovary syndrome (PCOS) is a common, complex, and chronic condition that presents many diagnostic and management challenges for managing clinicians. PCOS diagnosis in adolescents presents a particular challenge for treating clinicians due to the overlap of diagnostic features with normal physiological changes during adolescence. Adolescent diagnostic criteria include well-defined menstrual irregularity according to time postmenarche and hyperandrogenism, but does not require the use of pelvic ultrasound. Adolescents with only one criterion should be considered at risk of PCOS

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Groth, Susan W. "Adiponectin and Polycystic Ovary Syndrome." Biological Research For Nursing 12, no. 1 (2010): 62–72. http://dx.doi.org/10.1177/1099800410371824.

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Introduction. Polycystic ovary syndrome (PCOS) has a prevalence of 5—8% in women of reproductive age. Women with PCOS have an increased risk of metabolic syndrome and associated comorbidities. Adiponectin is a circulating protein produced by adipocytes. Circulating levels of adiponectin are inversely related to adipocyte mass. Low levels occur with insulin resistance, type 2 diabetes, metabolic syndrome, and obesity-related cardiovascular disease. This article reviews the literature on the link between adiponectin and PCOS and the potential use of adiponectin as a biomarker for PCOS. Method. D

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ZA, Raudhatun Nuzul, Rahmayani Rahmayani, Rulia Meilina, and Miftahul Jannah. "Efektivitas Penyuluhan Kesehatan Tentang Polycystic Ovary Sindrome (PCOS) Terhadap Pengetahuan Remaja Putri di SMA Negeri 4 Kota Banda Aceh." JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE 9, no. 1 (2023): 489. http://dx.doi.org/10.33143/jhtm.v9i1.2840.

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Polycystic Ovary Syndrome (PCOS) yang menyerang wanita usia subur pada usia remaja dapat menyebabkan gangguan menstruasi, kelebihan berat badan, Terdapat jerawat, Hirsutism, kerontokan rambut dan Penggelapan kulit di area leher. Penelitian ini merupakan penelitian quasi eksperimen, dengan menggunakan one group pretest posttest design, penelitian dilaksanakan pada tanggal 31 Mei s/d 10 Juni 2022, populasi dalam penelitian ini adalah remaja putri yang bersekolah di SMA Negeri 4 Kota Banda Aceh. Teknik pengambilan sampel menggunakan teknik menggunakan proportional random sampling yaitu 76 orang.

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Líška, Dávid, and Jozef Záhumenský. "Conservative possibilities influencing PCOS syndrome – the importance of nutrition." Česká gynekologie 86, no. 5 (2021): 343–48. http://dx.doi.org/10.48095/cccg2021343.

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Polycystic ovary syndrome (PCOS) is a common pathological condition in women. Conservative treatment is used in the treatment of polycystic ovary syndrome. Conservative treatment options include increased physical activity and diet. The main aim of the article is to discuss the therapeutic treatment of infl uencing PCOS from a nutritional point of view. PCOS is associated with several comorbidities, including infertility, metabolic syndrome, obesity, impaired glucose tolerance, diabetes mellitus II, and increased cardiovascular risk. Several therapeutic diets can be used in the treatment of PC

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Chakravorty, Triya Anushka. "Understanding Polycystic Ovary Syndrome (PCOS):." Physician 8, no. 2 (2023): 1–8. http://dx.doi.org/10.38192/1.8.2.3.

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Polycystic ovary syndrome (PCOS) is the commonest metabolic and endocrine disorder that affects women of reproductive age. It is characterised by irregular menstruation, hyperandrogenism and polycystic ovarian morphology. While significant progress has been made in understanding PCOS, several research questions remain. For instance, there is a need for further investigation into the aetiology of PCOS, including the role of genetic and environmental factors, to aid in earlier diagnosis and treatment. Additionally, while some therapies have been effective in managing the symptoms of PCOS, their

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Pinar, Gul. "The Relationship between Polycystic Ovary Syndrome and Psychological Symptoms." Journal of Clinical Research and Reports 7, no. 1 (2021): 01–09. http://dx.doi.org/10.31579/2642-9756/040.

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Background: Polycystic ovary syndrome (PCOS) is a common metabolic and endocrine disease among women of reproductive-age, which cause prone to psychological symptoms. Aim: The aim of the study is to assess the relationship between PCOS and psychological symptoms. Method: This case control study was conducted in the Gynecology Clinic of a Private University Hospital, Ankara, Turkey in 2016. The study conducted on patients with PCOS who received therapy in Gynecologic Oncology Center of a Private University Hospital in Ankara, Turkey. A total of 80 women with PCOS were administered The Survey Fo

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Yakovlev, Pavel P., and Igor Yu Kogan. "Endometrium and polycystic ovary syndrome." Journal of obstetrics and women's diseases 67, no. 4 (2018): 60–66. http://dx.doi.org/10.17816/jowd67460-66.

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Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. Patients with PCOS present with several endometrial abnormalities possibly explaining some of the adverse endometrium-related outcomes in these women. PCOS is inconsistently associated adverse pregnancy outcomes and an increased risk of endometrial cancer. The purpose of this review is to systematize the available data on endometrial dysfunction associated with PCOS. (For citation: Yakovlev PP, Kogan IYu. Endometrium and polycystic ovary syndrome. Journal of Obstetrics and Women’s Diseases. 201

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18

Hsieh, Yun-Chiao, Po-Kai Yang, and Mei-Jou Chen. "Metabolic Syndrome in Polycystic Ovary Syndrome." Fertility & Reproduction 03, no. 04 (2021): 125–35. http://dx.doi.org/10.1142/s2661318221500158.

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Polycystic ovary syndrome (PCOS) is a common endocrinopathy in women of reproductive age. Although its essential clinical manifestation includes a plethora of symptoms and signs, which largely reflects the underlying hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology, PCOS may also be associated with many metabolic derangements. These metabolic derangements happen to overlap with many of the core constituents of the metabolic syndrome (MBS)—increased insulin resistance, central obesity, and dyslipidemia. The two disorders also display similarly increased risks for certain m

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Djuraev, Jamolbek A., Abdurasul J. Botirov, Azizkhon Z. Shaumarov, et al. "POLYCYSTIC OVARY SYNDROME: A MODERN VIEW ON THE PROBLEM." International Journal of Medical Sciences And Clinical Research 03, no. 02 (2023): 83–87. http://dx.doi.org/10.37547/ijmscr/volume03issue02-16.

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The author of this article presents a modern understanding of the problem of polycystic ovary syndrome (PCOS). PCOS is a multifactorial, genetically determined pathological condition, in the pathogenesis of which an important role belongs to disorders of gonadotropic regulation, hyperandrogenism, insulin resistance, adipose tissue dysfunction and other factors. Obviously, PCOS is a socially significant gynecological pathology of early reproductive age, which requires optimization of the diagnosis and management of such patients from adolescence. In adolescents, PCOS is diagnosed in the presenc

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Gleicher, Norbert, Sarah Darmon, Pasquale Patrizio, and David H. Barad. "Reconsidering the Polycystic Ovary Syndrome (PCOS)." Biomedicines 10, no. 7 (2022): 1505. http://dx.doi.org/10.3390/biomedicines10071505.

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Though likely the most common clinical diagnosis in reproductive medicine, the Polycystic Ovary Syndrome (PCOS) is still only poorly understood. Based on previously published research, and here newly presented supportive evidence, we propose to replace the four current phenotypes of PCOS with only two entities—a hyperandrogenic phenotype (H-PCOS) including current phenotypes A, B, and C, and a hyper-/hypoandrogenic phenotype (HH-PCOS), representing the current phenotype D under the Rotterdam criteria. Reclassifying PCOS in this way likely establishes two distinct genomic entities, H-PCOS, prim

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Szymura, Marta, Marek Jarosław Molenda, Oliwia Brygida Woszczyńska, et al. "Polycystic Ovary Syndrome - treatment update." Quality in Sport 43 (July 12, 2025): 61348. https://doi.org/10.12775/qs.2025.43.61348.

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Introduction: Polycystic Ovary Syndrome (PCOS) is one of the most common endocrine disorders. It gets its name from the characteristic appearance of the ovaries observed in ultrasound imaging. Statistically, PCOS affects about 4-12% of women of reproductive age. PCOS can have a variety of symptoms and courses, and its causes have not been fully understood. Women with PCOS are at a higher risk of developing diabetes, hypertension, hyperlipidemia, and endometrial cancer compared to their healthy peers. The purpose of our work is to discuss the available methods used in the treatment of this synd

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Kandaraki, Eleni, Charikleia Christakou, and Evanthia Diamanti-Kandarakis. "Metabolic syndrome and polycystic ovary syndrome... and vice versa." Arquivos Brasileiros de Endocrinologia & Metabologia 53, no. 2 (2009): 227–37. http://dx.doi.org/10.1590/s0004-27302009000200014.

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The metabolic syndrome (MS) and the polycystic ovary syndrome (PCOS) appear to be interrelated, although they are distinct entities. Women with PCOS appear to be commonly affected by MS, while women with MS may display reproductive or endocrine features of PCOS. These clinical observations appear to be only partly attributable to the association of both syndromes with obesity and imply a reciprocal pathophysiologic relationship between PCOS and MS with potentially significant clinical sequelae. Adult women with MS are at a greater risk of developing cardiovascular disease; women with PCOS also

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Grześk-Kaczyńska, Magdalena, Magdalena Ostrowska, Dominika Pałac, and Szymon Kaczyński. "Polycystic ovary syndrome and pregnancy - review." Journal of Education, Health and Sport 12, no. 6 (2022): 221–28. http://dx.doi.org/10.12775/jehs.2022.12.06.022.

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Introduction and purpose Polycystic Ovary Syndrome(PCOS) is one of the most common endocrinological disorders, and it affects 7-8 % of women globally. It is very heterogenous disease, which pathogenesis is complex and composed of many factors like genetics, hormonal changes, environmental factors and insulin resistance. PCOS has many symptoms, which appearance is dependent on comorbidities like obesity, diabetes mellitus, hypercholesterolemia. Due to complexity of the pathogenesis of PCOS it may have four phenotypes: A,B,C,D. The pregnancy pathologies connected to PCOS are mainly gestational d

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Kim, Jin Ju. "Update on polycystic ovary syndrome." Clinical and Experimental Reproductive Medicine 48, no. 3 (2021): 194–97. http://dx.doi.org/10.5653/cerm.2020.04329.

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Polycystic ovary syndrome (PCOS) is a common disorder in reproductive-age women. In 2018, an international evidence-based guideline announced recommendations spanning a wide range of issues on the assessment and management of PCOS. From the 166 recommendations, the present study reviews those that are of particular clinical relevance for daily practice and introduces other relevant studies that have been published since the global guideline. The 2018 guideline increased the antral follicle count cutoff for the diagnosis of PCOS from 12 to 20 when using a high-frequency probe. Hirsutism was def

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Popova, P. V., I. V. Gorelova, and E. N. Grineva. "Polycystic ovary syndrome and cardiovascular risk." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 24, no. 6 (2019): 654–65. http://dx.doi.org/10.18705/1607-419x-2018-24-6-654-665.

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Polycystic ovary syndrome (PCOS) is a common endocrine disease in women of reproductive age. In addition to hyperandrogenism, impaired ovulation and fertility, PCOS is associated with an increased detection of cardiovascular risk factors such as obesity, insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, arterial hypertension, and obstructive sleep apnea. The initial stages of the atherosclerotic process are also well documented in women with PCOS. However, data from prospective studies on the end points of cardiovascular morbidity and mortality are scarce and controvers

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Kiryushkina, D. A. "From the history of polycystic ovary syndrome." Obstetrics, Gynecology and Reproduction 13, no. 3 (2019): 261–64. http://dx.doi.org/10.17749/2313-7347.2019.13.3.261-264.

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Polycystic ovary syndrome (PCOS) is a gynecological disease manifested in polycystic ovarian morphology, oligo/ anovulation, hyperandrogenism, hirsutism, alopecia, and acne. PCOS affects 5–10 % of women of reproductive age. The first histological description of polycystic ovaries was made by Antonio Vallisneri. Then, Kronid Fedorovich Slavyanskiy, for the first time, described the clinical picture of PCOS, and Sergey Kuzmich Lesnoy proposed ovary wedge resection for surgical treatment. Irving Stein and Michael Leventhal studied the PCOS symptom complex and provided the recommendations on its d

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Patel, Swarup S., and Vincent Bamigboye. "Polycystic ovary syndrome." Morecambe Bay Medical Journal 4, no. 12 (2005): 332–37. http://dx.doi.org/10.48037/mbmj.v4i12.901.

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The term polycystic ovary syndrome (PCOS) is a misnomer as it gives an impression of an ovarian disease with cysts. It is, however, a multisystem disorder with very distressing signs and symptoms and long term consequences on the well being of the patient. Ms Patel and Mr Bamigboye, respectively specialist registrar and consultant in obstetrics and gynaecology, describe this common and complicated condition and its modern management.

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Ibrahim, Gehan, Dima AlNowaiser, Howaida AlAbbasi, et al. "The relationship between lifestyle and the frequency of polycystic ovary syndrome in Saudi female residing in Riyadh." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 1 (2017): 20. http://dx.doi.org/10.18203/2320-1770.ijrcog20175826.

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Background: Polycystic Ovary Disorder (PCOS) is perceived as the most widely recognized endocrinopathy in reproductive women. This study aimed to assess the relationship between the lifestyle and frequency of polycystic ovary syndrome in Saudi Arabia.Methods: This is a case-control study conducted on females at princess Nourah University (PNU), King Fahad Medical City (KFMC) and malls in Riyadh city, Saudi Arabia. The study included females in the reproductive age including 401 controls and 122 PCOS cases.Results: History of pregnancy related disorders was higher among the PCOS women in compar

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С., Б. Чечуга. "POLYCYSTIC OVARY SYNDROME HORMONAL PHARMACOTHERAPY." REPRODUCTIVE ENDOCRINOLOGY, no. 45 (February 28, 2019): 52–56. https://doi.org/10.18370/2309-4117.2019.45.52-56.

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Polycystic ovary syndrome (PCOS) is a diagnosis of exclusion and an important interdisciplinary problem. New recommendations for PCOS management were presented to the world in 2018. These recommendations have been developed by the CREPCOS (Australia), ESHRE, ASRM, and more than 30 other organizations. This document based on evidence-based medicine data and replaces previous recommendations for the PCOS management 2011. This article presents a translation of only one section of recommendations on the PCOS pharmacotherapy. It is also presents the results of the combined oral contraceptive Belara

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Szeliga, Anna, Ewa Rudnicka, Marzena Maciejewska-Jeske, et al. "Neuroendocrine Determinants of Polycystic Ovary Syndrome." International Journal of Environmental Research and Public Health 19, no. 5 (2022): 3089. http://dx.doi.org/10.3390/ijerph19053089.

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Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women and a major cause of anovulatory infertility. A diagnosis of PCOS is established based the presence of two out of three clinical symptoms, which are criteria accepted by the ESHRE/ASRM (European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine). Gonadotropin-releasing hormone (GnRH) is responsible for the release of luteinizing hormone, and follicle stimulating hormone from the pituitary and contributes a leading role in controlling reproductive function in humans. The goal of

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Ojaniemi, Marja, and Michel Pugeat. "An adolescent with polycystic ovary syndrome." European Journal of Endocrinology 155, suppl_1 (2006): S149—S152. http://dx.doi.org/10.1530/eje.1.02270.

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Polycystic ovary syndrome (PCOS) is a common clinical condition that manifests during adolescence with menstrual irregularities, acne, and hirsutism. As these symptoms are frequently observed in healthy teenagers, it can be difficult to recognize PCOS. Establishment of hyperandrogenism, polycystic ovaries, and identifying a metabolic disorder are required for the management of PCOS in a teenager. The underlying defects in PCOS are still unclear; however, insulin resistance and the metabolic syndrome are common in both obese and non-obese PCOS patients, so that the evaluation of glucose toleran

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Wasan Wajdi Ibrahim, Ekhlas Jabbar Kadhim, Nada Saeed Abbas, Saba Ryadh ‎Younis, and Hayder Adnan Fawzi. "Serological markers of autoimmunity ‎in women with polycystic ovary ‎syndrome." International Journal of Research in Pharmaceutical Sciences 10, no. 3 (2019): 1746–50. http://dx.doi.org/10.26452/ijrps.v10i3.1366.

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In the present study, we evaluate the serum level of common autoimmunologic markers in ‎women with polycystic ovary syndrome (PCOS) and study their relationship with ‎hormonal ‎parameters. The study was ‎an observational case-control study, done in a Tertiary referral hospital, the study ‎included ‎50 women with polycystic ovary syndrome and 50 matched control.‎ Serum levels of Antinuclear Antibody (ANA) and anti-double-stranded DNA (dsDNA) were significantly higher in polycystic ovary ‎syndrome women compared to control. Also, luteinizing hormone (LH), follicle stimulating hormone (FSH), and

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Esmaeilzadeh, Seddigheh, Mouloud Agajani Delavar, Mania Amiri, Soraya Khafri, and Nargess Gholizadeh Pasha. "Polycystic ovary syndrome in Iranian adolescents." International Journal of Adolescent Medicine and Health 26, no. 4 (2014): 559–65. http://dx.doi.org/10.1515/ijamh-2013-0335.

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Abstract Objective: Polycystic ovary syndrome (PCOS) is linked with metabolic syndrome, which includes obesity, insulin resistance, dyslipidemia, and endocrine function in patients with PCOS. The aim of this study was to determine the prevalence of adolescent PCOS and characteristics associated with PCOS in adolescents in Babol, Iran. Materials and methods: A cross-sectional study was conducted on 1549 girl high school students aged 16–20 years who were living in Iran. After overnight fasting, blood samples were collected to determine hormones and lipid levels in PCOS patients between the firs

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Vrbikova, Jana, Martin Hill, Bela Bendlova, et al. "Incretin levels in polycystic ovary syndrome." European Journal of Endocrinology 159, no. 2 (2008): 121–27. http://dx.doi.org/10.1530/eje-08-0097.

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ObjectivePolycystic ovary syndrome (PCOS) has been linked to a high risk of type 2 diabetes mellitus. Disturbances in the secretion of the incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) have been observed in states with impaired glucose regulation. This paper considers the secretion of GIP and GLP-1 after oral glucose load in a group of lean, glucose-tolerant PCOS women in comparison with age- and body mass index (BMI)-matched healthy women.DesignCase control.MethodsPCOS (n=21, 25.8±4.1 years, BMI 21.6±1.7 kg/m2) and control healthy wom

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Ruddenklau, Amy, and Rebecca E. Campbell. "Neuroendocrine Impairments of Polycystic Ovary Syndrome." Endocrinology 160, no. 10 (2019): 2230–42. http://dx.doi.org/10.1210/en.2019-00428.

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Abstract Polycystic ovary syndrome (PCOS) is a prevalent and distressing disorder of largely unknown etiology. Although PCOS defined by ovarian dysfunction, accumulating evidence supports a critical role for the brain in the ontogeny and pathophysiology of PCOS. A critical pathological feature of PCOS is impaired gonadal steroid hormone negative feedback to the GnRH neuronal network in the brain that regulates fertility. This impairment is associated with androgen excess, a cardinal feature of PCOS. Impaired steroid hormone feedback to GnRH neurons is thought to drive hyperactivity of the neur

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Kurniawati, Erna Yovi, Noor Pramono, Syarief Thaufik Hidayat, and Endang Mahati. "Polycystic Ovary Syndrome Markers and Mechanism." Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan 15, no. 1 (2024): 37. http://dx.doi.org/10.32502/sm.v15i1.7829.

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Polycystic ovary syndrome (PCOS) is a complex endocrine disorder characterized by hormonal imbalances, metabolic dysregulation, and reproductive abnormalities. This study aims to elucidate the significance of PCOS markers and their mechanisms while outlining the methodology employed. A comprehensive literature review was conducted from 2020 to 2023 using databases like PubMed, ScienceDirect, EMBASE, and Google Scholar. Key search terms included "pathophysiology," "pathogenesis," "PCOS," "marker," and "biomarker," aligned with the PICOT criteria. After removing duplicates, articles underwent a

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Mansi, R. Patil, S. Chaudhari Hitendra, Sunil P. Pawar Dr, et al. "An Overview on Polycystic Ovary Syndrome." Journal of Advanced Research and Reviews in Medical & Medicine 1, no. 2 (2024): 29–41. https://doi.org/10.5281/zenodo.11195395.

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<em>PCOS is an endocrine condition that affects females who are of reproductive age.</em><em> Despite this, the illness is plagued by difficult diagnostic procedures, delayed diagnoses, and inadequate treatment plans. Infertility, insulin resistance, obesity, and cardiovascular disorders are just a few of the health concerns brought on by this syndrome. PCOS is a polygenic, multifactorial, autoimmune, inflammatory, and dysregulated steroid state condition that primarily manifests as a result of poor lifestyle choices. PCOS in the affected females can now be identified thanks to the development

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Dewi, Ni Luh Putu Rustiari. "Pendekatan Terapi Polycystic Ovary Syndrome (PCOS)." Cermin Dunia Kedokteran 47, no. 11 (2020): 703. http://dx.doi.org/10.55175/cdk.v47i11.1201.

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<p>Polycystic Ovary Syndrome (PCOS) juga dikenal sebagai hyperandrogenic anovulation (HA), merupakan kelainan sistem endokrin yang menyebabkan gangguan kesuburan wanita usia reproduktif. PCOS melibatkan ketidakseimbangan kadar luteinizing hormone (LH) dan follicle-stimulating hormone (FSH), resistensi insulin, dan kelainan metabolisme. Clomiphene citrate masih menjadi pilihan terapi utama untuk menstimulasi ovulasi pada kasus PCOS. Metformin juga menurunkan kadar androgen yang dapat meningkatkan terjadinya ovulasi spontan. Terapi lini kedua adalah gonadotropin dan bedah laparoskopi ovari

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Motta, Alicia Beatriz. "Epigenetic Marks in Polycystic Ovary Syndrome." Current Medicinal Chemistry 27, no. 39 (2020): 6727–43. http://dx.doi.org/10.2174/0929867326666191003154548.

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: Polycystic Ovary Syndrome (PCOS) is a common endocrine and metabolic disorder that affects women in their reproductive age. Recent studies have shown that genes have an important role in the etiology of PCOS. However, the precise way in which these genes are transcriptionally and post-transcriptionally regulated is poorly understood. : The aim of the present review is to provide updated information on miRNAs and DNA methylation as epigenetic marks of PCOS. : The data presented here allow concluding that both microRNAs and DNA methylation can be considered as possible useful biomarkers when c

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Hu, Cong, Bo Pang, Zhanchuan Ma, and Huanfa Yi. "Immunophenotypic Profiles in Polycystic Ovary Syndrome." Mediators of Inflammation 2020 (March 19, 2020): 1–10. http://dx.doi.org/10.1155/2020/5894768.

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Polycystic ovary syndrome (PCOS) a long-known endocrinopathy and one of the most common endocrine-reproductive-metabolic disorders in women, which can lead to infertility. Although the precise etiology remains unclear, PCOS is considered as a complex genetic trait, with a high degree of heterogeneity. Besides, hormones and immune cells, including both innate and adaptive immune cells, are reportedly a cross talk in PCOS. Chronic low-grade inflammation increases autoimmune disease risk. This proinflammatory condition may, in turn, affect vital physiological processes that ultimately cause infer

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Mudasir, Maqbool Dr. Nazia Nasir Dr. Sajjad Mustafa. "POLYCYSTIC IN OVARIAN SYNDROME AND ITS VARIOUS TREATMENT STRATEGIES." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 09 (2018): 8670–78. https://doi.org/10.5281/zenodo.1412698.

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<em>Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder, leading to several health complications, including menstrual dysfunction, infertility, hirsutism, acne, obesity, and metabolic syndrome. Polycystic ovary syndrome (PCOS) is a complex condition characterized by elevated androgen levels, menstrual irregularities, and/or small cysts on one or both ovaries. PCOS affects as many as 10% of reproductive-age women when using the NIH criteria for diagnosis, and up to 18% of reproductive-age women are diagnosed with PCOS as per the Rotterdam criteria. The exact pathophysiology o

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Gihan, M. C., A. A. W. M. Wijerathna, and P. A. C. P. Pathiraja. "Polycystic ovarian syndrome." Sri Lanka Journal of Obstetrics and Gynaecology 46, no. 1 (2024): 11–16. http://dx.doi.org/10.4038/sljog.v46i1.8118.

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The most common hormonal disorder in women at reproductive age is the Polycystic Ovary Syndrome (PCOS) and the complex pathophysiology of PCOS and its substantial health repercussions, which include obesity, cancer, cardiovascular disease, diabetes, and psychological morbidities, have made it a major global health concern for women. The aim of the present review article is to summarize the literature available on PCOS and to identify the pathophysiology, diagnosis criteria and the treatments for the disease.

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Banerjee, Soma, Laura G. Cooney, and Aleksandar K. Stanic. "Immune Dysfunction in Polycystic Ovary Syndrome." ImmunoHorizons 7, no. 5 (2023): 323–32. http://dx.doi.org/10.4049/immunohorizons.2200033.

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Abstract Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-aged individuals with ovaries. It is associated with anovulation and increased risk to fertility and metabolic, cardiovascular, and psychological health. The pathophysiology of PCOS is still inadequately understood, although there is evidence of persistent low-grade inflammation, which correlates with associated visceral obesity. Elevated proinflammatory cytokine markers and altered immune cells have been reported in PCOS and raise the possibility that immune factors contribute to ovulatory dysfunct

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Wang, Yan, Xiaorong Ma, Jiashou Luo, Xiaoyan Wang, and Lu Han. "Expression of Serum PSA, Nesfatin-1, and AMH in Patients with Polycystic Ovary Syndrome." Cellular and Molecular Biology 67, no. 5 (2022): 57–63. http://dx.doi.org/10.14715/cmb/2021.67.5.8.

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Insulin resistance and hyperandrogenism are the leading causes of polycystic ovary syndrome (PCOS). Therefore, it has great significance to study the expression levels of PSA, nesfatin-1, and AMH. To provide some reference for clinical diagnosis and treatment of polycystic ovary syndrome (PCOS), the expression levels of PSA, nesfatin-1, and AMH in serum of patients with polycystic ovary syndrome (PCOS) were investigated. The experimental group consisted of 200 patients with polycystic ovary syndrome treated in Shanghai Huashan Hospital from July 2018 to July 2019. The control group consisted o

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Deans. "Polycystic Ovary Syndrome in Adolescence." Medical Sciences 7, no. 10 (2019): 101. http://dx.doi.org/10.3390/medsci7100101.

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Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in females, and is characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology based on ultrasound. Controversy surrounds the optimum diagnosis and management in the adolescent population. Many patients with adult PCOS present with pathognomonic symptoms as adolescents, and there is value in early diagnosis due to the associated long-term metabolic and reproductive health sequalae. A definitive diagnosis does not need to be made prior to implementing treatment in this group of young w

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A.Ali, Hanaa, Majid K. Hussain, and Oda M. Yasser. "Hormonal Profile and Oxidative Stress are Directed by Anthropometric Measures in Polycystic Ovary syndrome." Al-Kufa University Journal for Biology 7, no. 3 (2015): 55–67. http://dx.doi.org/10.36320/ajb/v7.i3.8072.

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V, Babitha, Varun B V, Upendra K, and Supreeth A. "POLYCYSTIC OVARY SYNDROME USING MACHINE LEARNING." International Research Journal of Computer Science 9, no. 8 (2022): 228–34. http://dx.doi.org/10.26562/irjcs.2022.v0908.15.

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One of the most common hormonal conditions in women of reproductive age is polycystic ovarian syndrome (PCOS). Since pcos is frequently linked to obesity, type 2 diabetes mellitus, and high cholesterol levels, early detection and treatment are crucial. By counting the number of follicles in an ovarian ultrasound image and adding clinical, biochemical, and imaging characteristics, pcos can be automatically detected and patients divided into normal and pcos-affected groups. The body mass index (BMI), hormone levels, and other factors are all taken into consideration by the Support Vector Machine

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Bajuk Studen, Katica, and Marija Pfeifer. "Cardiometabolic risk in polycystic ovary syndrome." Endocrine Connections 7, no. 7 (2018): R238—R251. http://dx.doi.org/10.1530/ec-18-0129.

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Polycystic ovary syndrome (PCOS) is a common disorder in women of reproductive age. Besides hyperandrogenism, oligomenorrhea and fertility issues, it is associated with a high prevalence of metabolic disorders and cardiovascular risk factors. Several genetic polymorphisms have been identified for possible associations with cardiometabolic derangements in PCOS. Different PCOS phenotypes differ significantly in their cardiometabolic risk, which worsens with severity of androgen excess. Due to methodological difficulties, longer time-scale data about cardiovascular morbidity and mortality in PCOS

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Carol Gabriela Guerrero Acevedo and Jairo Alejandro Estrada Morales. "Polycystic ovary syndrome." GSC Biological and Pharmaceutical Sciences 31, no. 1 (2025): 163–72. https://doi.org/10.30574/gscbps.2025.31.1.0129.

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Polycystic Ovary Syndrome (PCOS) is a heterogeneous disorder and a frequent cause of consultation in adolescents. The etiology is multifactorial, involving genetic and environmental factors (intrauterine and extrauterine).1 The clinical manifestations are hirsutism, menstrual irregularities, and acne. In addition, metabolic alterations such as hyperinsulinemia, insulin resistance, dyslipidemia and obesity are also associated.2 The objectives of the treatment are to achieve ovulation, normalize menstrual cycles, reduce and if possible, eliminate hirsutism and acne, obtain an acceptable weight l

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Di Pietro, Mariana, Natalia Pascuali, Fernanda Parborell, and Dalhia Abramovich. "Ovarian angiogenesis in polycystic ovary syndrome." Reproduction 155, no. 5 (2018): R199—R209. http://dx.doi.org/10.1530/rep-17-0597.

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Polycystic ovary syndrome (PCOS) is the most prevalent endocrine pathology among women in reproductive age. Its main symptoms are oligo or amenorrhea, hyperandrogenism and the presence of ovarian cysts. It is also associated with infertility, obesity and insulin resistance. Mainly due to its heterogeneity, PCOS treatments are directed to manage its symptoms and to prevent associated diseases. The correct formation and regression of blood vessels during each ovarian cycle is indispensable for proper follicular development, ovulation and corpus luteum formation. The importance of these processes

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