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Journal articles on the topic 'Polycythamia; Hypertension'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Khilendra, Kumar Sahu Ankita Damahe* Antra Sahu Nilesh kumar Devki Markande Chunesh kumar Janvi NilMarkar. "A Review on Novel Approaches for Cure, Diagnosis, Treatment and Future Direction in Polycythemia." International Journal of Scientific Research and Technology 2, no. 2 (2025): 102–10. https://doi.org/10.5281/zenodo.14852627.

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An excess of red blood cells in the body is known as polycythemia. The blood becomes thicker due to the additional cells, which raises the risk of blood clots and other health problems.  There are various causes of polycythemia, and each one has a unique course of treatment. Discover more about polycythemia's causes, symptoms, and available treatments in this article. An rise in hemoglobin or hematocrit levels over the standard values is known as polycythemia. The majority of its causes are linked to the development of hyper viscosity, and the majority of cases are classified as primary o

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Válkova, Z., and M. Vymazal. "Intraokuläre Hypertension bei Polycythaemia vera." Spektrum der Augenheilkunde 8, no. 6 (1994): 284–85. http://dx.doi.org/10.1007/bf03163720.

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3

Coulthard, M. G. "Polycythaemia and hypertension caused by renal artery stenosis." Archives of Disease in Childhood 86, no. 4 (2002): 307–8. http://dx.doi.org/10.1136/adc.86.4.307.

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4

Tachi, Kenneth, Victor Ekem, and Yvonne Dei-Adomakoh. "Delayed diagnosis of polycythaemia vera in an adult female with non-cirrhotic portal hypertension." Ghana Medical Journal 56, no. 1 (2022): 38–41. http://dx.doi.org/10.4314/gmj.v56i1.6.

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Polycythaemia vera (PV) is a rare myeloproliferative neoplasm characterized primarily by erythrocytosis and an in-creased risk of thrombosis. We report a case of PV in a 60-year-old female with diabetes mellitus (DM) and a past history of recurrent abdominal pain and documented oesophageal varices who was followed up for 2 years as a case of non-cirrhotic portal hypertension of unknown cause. PV was only diagnosed after persistent complaints of vaso-motor symptoms and better scrutiny of full blood count results.

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Khandait, Vinod, Sneha S. Bhujle, and Nandita Bagchi. "Acute Myocardial Infarction in a Patient of Polycythaemia Vera." Vidarbha Journal of Internal Medicine 32 (January 31, 2022): 59–62. http://dx.doi.org/10.25259/vjim_8_2021.

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Polycythaemia Vera is the most common form of myeloproliferative neoplasm.The median age of diagnosis is 60 years. Atherosclerosis is the most common cause of myocardial infarction, however other causes too should be looked for in the patients. Here, we present a case of 62 year old female who was a known case of hypertension and Ischemic heart disease on regular medications. She came with complaints of chest pain for the past 2 days. ECG showed NSTEMI with raised cardiac enzymes. She developed left side hemiparesis after admission, and the CT head showed acute infarct in right frontal lobe. S

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Moore-Gillon, J. C., and I. R. Cameron. "Right ventricular hypertrophy and polycythaemia in rats after intermittent exposure to hypoxia." Clinical Science 69, no. 5 (1985): 595–99. http://dx.doi.org/10.1042/cs0690595.

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1. Six groups of 20 male adult rats were maintained in an environmental chamber, each group for a period of 28 days. One group breathed air throughout its experimental period, and a second group breathed a normobaric atmosphere of 12% oxygen. The other four groups were exposed to this hypoxic atmosphere for only a proportion of each 24 h cycle: 2, 4 and 12 h daily, and eight periods of 30 min daily. 2. After 28 days, measurement was made, in each rat, of right ventricule (RV) weight and of red cell mass (RCM) by using 51Cr-labelled rat erythrocytes. 3. In the normoxic control group, RV weight

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Girish, T., M. P. Lamb, T. P. Rollason, and L. J. R. Brown. "An endometrioid tumour of the ovary presenting with hyperandrogenism, secondary polycythaemia and hypertension." BJOG: An International Journal of Obstetrics and Gynaecology 108, no. 3 (2001): 330–32. http://dx.doi.org/10.1111/j.1471-0528.2001.00063.x.

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Girish, T., M. P. Lamb, T. P. Rollason, and L. J. R. Brown. "An endometrioid tumour of the ovary presenting with hyperandrogenism, secondary polycythaemia and hypertension." British Journal of Obstetrics and Gynaecology 108, no. 3 (2001): 330–32. http://dx.doi.org/10.1016/s0306-5456(00)00063-2.

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Rao, Raunak, Spoorthy Kulkarni, and Ian B. Wilkinson. "Two Cases of Severe Hypertension in JAK2 Mutation-Positive Myeloproliferative Neoplasms." Case Reports in Vascular Medicine 2020 (November 7, 2020): 1–6. http://dx.doi.org/10.1155/2020/8887423.

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Background. Myeloproliferative neoplasms are a heterogeneous group of disorders resulting from the abnormal proliferation of one or more terminal myeloid cells—established complications include thrombosis and haemorrhagic events; however, there is limited evidence to suggest an association with arterial hypertension. Herein, we report two independent cases of severe hypertension in JAK2 mutation-positive myeloproliferative neoplasms. Case Presentations. Case 1: a 39-year-old male was referred to our specialist hypertension unit with high blood pressure (BP) (200/120 mmHg), erythromelalgia, and

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Janender Baghel, Dhiraj Jhamb, Rajesh Kumar, and Kaushik Chatterjee. "Prevalence of Lifestyle Diseases in Non-Acclimatized Lowlanders at High Altitude in subdivision Darjeeling district of Eastern Himalayan Region, India." Indian Journal of Public Health Research & Development 15, no. 2 (2024): 136–41. http://dx.doi.org/10.37506/1qg0a273.

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Background: Lifestyle diseases including overweight, obesity, hypertension and metabolic syndrome leads toheart diseases, increased risk for insulin resistance, diabetes and stroke. Obesity is one of the lifestyle diseases declared as worldwide epidemic which is a major health burden. The study determine the association of lifestylediseases with Body Mass Indexinnon-acclimatized lowlanders at altitude of 7500 ft above sea level and to estimate effect of altitude on anthropometric and biochemical parameters.Methods: The total of 300 male age between 20-57 years studied. The present retrospectiv

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Jain, Neeraj, Dnyaneshwar Jadhav, Akash Chheda, et al. "Major Neurological Syndromes with COVID-19: Lessons to Learn." SciMedicine Journal 4, no. 1 (2022): 13–24. http://dx.doi.org/10.28991/scimedj-2022-0401-02.

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Objective: Covid-19 is a highly infectious viral disease, and our understanding of the impact of this virus on the nervous system is limited. Therefore, we aimed to do a systematic analysis of the neurological manifestations. Methods: We retrospectively studied the clinical, laboratory, and radiological findings of patients with major neurological syndromes (MNS) in Covid-19 over 6 months. Results: We had 39 patients with major neurological syndromes (MNS). The most common MNS was cerebrovascular disease (CVD) (61.53%), in which ischemic stroke (83.33%), cortical sinus thrombosis (12.50%), and

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Omoniyi, O. S., I. B. Fajolu, A. Adediran, E. O. Temiye, and J. I. Ladele. "Clinical and haematological features of newborns of mothers with hypertensive disorders in pregnancy in Lagos, Nigeria." Nigerian Journal of Paediatrics 47, no. 3 (2020): 252–57. http://dx.doi.org/10.4314/njp.v47i3.10.

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Background: Newborns of mothers with hypertensive disorders in pregnancy have an increased risk of preterm delivery, low birth weight, perinatalasphyxia and haematological derangements such as polycythaemia, thrombocytopenia and neutropenia. These morbidities are associated with uteroplacental insufficiency. The haematological derangements however have not been studied in detail in African neonates. Objective: To determine the clinical and haematological features of newborns of hypertensive mothers Methods: Cross-sectional study involving 250 newborns; 125 newborns each of hyperten

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Augustine, Amie-Anne, Jin Hui Ho, and Hwee Ching Tee. "A RARE PRESENTATION OF MEDULLARY THYROID CARCINOMA." Journal of the ASEAN Federation of Endocrine Societies 40, S1 (2025): 103–4. https://doi.org/10.15605/jafes.040.s1.176.

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INTRODUCTION/BACKGROUNDMedullary thyroid carcinoma (MTC) is a rare neuroendocrine tumour arising from the parafollicular C cells of the thyroid gland, accounting for approximately 4% of all thyroid malignancies. We present a case of MTC with an unusual and life-threatening initial manifestation — cardiac tamponade — which led to the diagnosis. CASEA 63-year-old Kadazan male with a medical history of myocardial infarction with non-obstructive coronary arteries (MINOCA) in 2017, intracranial haemorrhage in 2018, polycythaemia rubra vera, dyslipidaemia, hypertension, and type 2 diabetes mellitus,

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Mohan Rao, Preethi, Nishant Ranjan, and Thomas Hugh Jones. "PMON266 The Effect of Testosterone Replacement Therapy on Cardiovascular Safety and Other Adverse Effects – a Randomised Double Blinded Placebo Controlled Trial (STRIDE Study)." Journal of the Endocrine Society 6, Supplement_1 (2022): A704. http://dx.doi.org/10.1210/jendso/bvac150.1451.

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Abstract Background Concerns about testosterone treatment and its safety ranging from cardiovascular risk to prostate cancer risk to polycythaemia and obstructive sleep apnoea has always been controversial especially cardiovascular safety. To tip the balance, there were 3 trials that were published in the recent past which induced more controversy by demonstrating that testosterone therapy increased cardiovascular disease and mortality. Our RCT evaluates the safety of testosterone Undecanoate in patients with type 2 diabetes and hypogonadism. Research design and methods: This is a randomised d

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Fogliatto, Laura, Raquel Breunig, Tito Vanelli Costa, et al. "The Assessment of the European Leukemianet Criteria for Clinicohematologic Resistance and Intolerance to Hydroxyurea in Polycythemia Vera Is Not Easily Applicable in Daily Practice." Blood 124, no. 21 (2014): 5550. http://dx.doi.org/10.1182/blood.v124.21.5550.5550.

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Abstract Background Polycythemia vera (PV) is a subgroup of myeloproliferative neoplasm (MPN) BCL-ABL1 negative. The current therapy of PV should be aimed at preventing vascular complications and avoid increasing the risk of leukemic transformation. The therapy response monitoring is based in the European LeukemiaNet (ELN) unified definition of clinical resistance and intolerance to hydroxycarbamide in polycythaemia vera consensus process, published by Barbui T et al in Br J Haematol 2010;148(6):961-963. Objectives We conducted a study to assess in our clinical practice the aplicability of the

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Mehta, Dipal, Holly Theaker, Donal P. McLornan, et al. "A Real World, Single-Centre Study of Young Adult Patients with Philadelphia Negative Myeloproliferative Neoplasms." Blood 142, Supplement 1 (2023): 6402. http://dx.doi.org/10.1182/blood-2023-189502.

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Classical ‘Philadelphia negative’ myeloproliferative neoplasms (MPNs) are clonal haematopoietic disorders and include essential thrombocythaemia (ET), polycythaemia vera (PV) and myelofibrosis (MF). MPNs have a heterogenous phenotype with an inherent risk of thromboembolic and haemorrhagic complications, and risk of blastic transformation. MPNs are commonly diagnosed in the 6 th decade or later, although up to 20% of patients are diagnosed &lt; 40 years. Current risk stratification and treatment guidance, however, is frequently extrapolated from older cohorts. Here, we present a comprehens

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Pires De Lima, Marta, Maria Eduarda Couto, Jorge Coutinho, Maria Gomes da Silva, and Fernanda Leite. "Januskinase-2 V617F Positive Myeloproliferative Neoplasms and Haemostatic Disorders: Importance of Obesity in Prediction of Thrombotic Events." Blood 132, Supplement 1 (2018): 5466. http://dx.doi.org/10.1182/blood-2018-99-112297.

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Abstract Introduction : Myeloproliferative neoplasms (MPN), namely polycythaemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) have been associated with an increased risk of thrombotic and haemorrhagic events, mainly when januskinase-2 (JAK 2) V617F mutation is detected1. This association is higher for thrombotic events (TE) contributing for overall mortality in MPN patients, although the pathophysiological mechanisms remain unclear. Although age and history of thrombosis have been considered the most important factors for thrombosis risk assessment, cardiovascular

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Chaudhary, Rajvi, Neel Vora, Darsh Patel, and Kartikey G Parmar. "CASE STUDY: JAK2 V617F NEGATIVE POLYCYTHAEMIA CAUSING PORTAL VENOUS HYPERTENSION WITHOUT EVIDENT PORTAL VEIN THROMBOSIS." INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH, August 1, 2022, 13–15. http://dx.doi.org/10.36106/ijsr/8506192.

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Polycythaemia is dened as an increase in the haemoglobin above normal. This increase may be real or only apparent because of a decrease in plasma volume (spurious or relative polycythaemia). Often patients with polycythaemia are detected through an incidental nding of elevated haemoglobin or haematocrit level. Patients with polycythaemia may be asymptomatic or experience symptoms related to the increased red cell mass or the underlying disease process that leads to the increased red cell mass. The dominant symptoms from an increased red cell mass are related to hyper viscosity and thrombosis

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van de Sande, Margot J. A., Femke Slaghekke, Arjan B. te Pas, Ruben S. G. M. Witlox, Enrico Lopriore, and Lisanne S. A. Tollenaar. "Increased risk of persistent pulmonary hypertension of the newborn in twin anaemia polycythaemia sequence donors." Fetal Diagnosis and Therapy, November 12, 2024, 1–19. http://dx.doi.org/10.1159/000542493.

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Introduction This study aimed to describe the prevalence and risk factors for respiratory complications in monochorionic twins with twin anaemia polycythaemia sequence (TAPS). Methods All neonates diagnosed with postnatal TAPS at our centre between 2002 and 2023 were included in this retrospective study. The primary outcome was the prevalence of respiratory complications, including respiratory distress syndrome (RDS), bronchopulmonary dysplasia (BPD) and persistent pulmonary hypertension of the newborn (PPHN). Secondary outcomes included need of respiratory support during admission and a risk-

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20

Forsell, S., A. Najeb, H. Habel, T. Jerberg, R. Hofmann, and P. Svensson. "Abnormal hb-levels associate differently with type 1 and type 2 myocardial infarction in patients visiting the emergency department with chest pain." European Heart Journal 42, Supplement_1 (2021). http://dx.doi.org/10.1093/eurheartj/ehab724.1451.

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Abstract Background Previous studies have found an association between myocardial infarction (MI) and abnormal haemoglobin (Hb) but it is unknown whether Hb-levels are associated with type 1 and type 2 MI in unselected patients with chest pain visiting the emergency department (ED). Purpose To investigate the association between abnormal Hb-levels and type 1 and type 2 MI in patientens visiting the ED with chest pain. Methods The study population comprised all consecutive patients visiting four urban ED:s for chest pain between 2013–2016 with available data on Hb. Clinical data from the ED vis

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Balcar, Lorenz, Lina Degenfeld‐Schonburg, Can Hopp, et al. "Non‐Invasive Stratification of Portal Hypertension in Patients With BCR::ABL1‐Negative Myeloproliferative Neoplasms." Liver International 45, no. 6 (2025). https://doi.org/10.1111/liv.70098.

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ABSTRACTBackground & AimsThe course of BCR::ABL1‐negative myeloproliferative neoplasms (MPN) is frequently complicated by thromboembolic events in the splanchnic venous system, resulting in portal hypertension (PH). Therefore, the introduction of spleen stiffness measurement (SSM) might improve the diagnosis of PH. The aim of this study was to evaluate the clinical utility of SSM (performed by using the 100 Hz probe) in non‐invasive stratification of PH in these patients.MethodsWe performed a retrospective, monocentric, cross‐sectional analysis including consecutive patients with BCR::ABL1

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Dunn, Matthew, Joshua Dawe, Beng Eu, Kevin Lee, Timothy Piatkowski, and Mark Stoové. "The health effects of non‐prescribed anabolic–androgenic steroid use: Findings from The Performance and image‐enhancing drugs UseRS' Health (PUSH) audit." Drug and Alcohol Review, July 7, 2024. http://dx.doi.org/10.1111/dar.13899.

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AbstractIntroductionTo ascertain the adverse health outcomes experienced by those using prescribed testosterone and non‐prescribed anabolic–androgenic steroids presenting to general practitioner (GP) clinics.MethodsRetrospective clinical audit from nine GP clinics in major metropolitan areas across three Australian states. Data included demographic and individual characteristics (age, sexuality, body mass index, smoking status and HIV status); performance and image‐enhancing drug use (type, reasons for use, patient‐reported adverse effects); and blood biochemistry measurements (lipid profiles,

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Gunawan, R. Y., and H. Medishita. "C42. Eisenmenger Syndrome, Could Its Pathophysiological Changes Serve as Protective Factors Against Severe COVID-19 Infection?" European Heart Journal Supplements 23, Supplement_F (2021). http://dx.doi.org/10.1093/eurheartjsupp/suab125.041.

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Abstract Background Congenital heart disease (CHD) and pulmonary artery hypertension (PAH) are comorbidities to severe COVID-19 infection. We reported a case of adult congenital heart disease (ACHD) with Eisenmenger Syndrome (ES) who survived COVID-19 without progression to severe infection. Case Description A 39 years old male with history of uncorrected ACHD complained of low-grade fever and cough for 3 days. Initial oxygen saturation was 85%, no tachypnoea, no tachycardia, and blood pressure was normal. SARS-CoV2 RT-PCR results was positive. Thorax CT showed lung fibrosis, minimal GGO, and

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Gunawan, R. Y., and H. Medishita. "C42. Eisenmenger Syndrome, Could Its Pathophysiological Changes Serve as Protective Factors Against Severe COVID-19 Infection?" European Heart Journal Supplements 23, Supplement_F (2021). http://dx.doi.org/10.1093/eurheartjsupp/suab124.041.

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Abstract Background Congenital heart disease (CHD) and pulmonary artery hypertension (PAH) are comorbidities to severe COVID-19 infection. We reported a case of adult congenital heart disease (ACHD) with Eisenmenger Syndrome (ES) who survived COVID-19 without progression to severe infection. Case Description A 39 years old male with history of uncorrected ACHD complained of low-grade fever and cough for 3 days. Initial oxygen saturation was 85%, no tachypnoea, no tachycardia, and blood pressure was normal. SARS-CoV2 RT-PCR results was positive. Thorax CT showed lung fibrosis, minimal GGO, and

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Wouter, Schutyser, Budts Werner, and Verhamme Peter. "Percutaneous embolization of pulmonary arteriovenous malformations in adult patient with Rendu-Osler-Weber: a case report." European Heart Journal - Case Reports, November 3, 2023. http://dx.doi.org/10.1093/ehjcr/ytad533.

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Abstract Background Hereditary haemorrhagic telangiectasia, or Rendu-Osler-Weber syndrome, is a rare genetic disorder characterized by the development of telangiectasias and arteriovenous malformations throughout the body. We present a case of percutaneous embolization of pulmonary arteriovenous malformations in an adult patient. Case summary A 26-year-old male patient with polycythaemia of unknown origin and a family history of secundum atrial septal defect underwent cardiac evaluation which revealed clubbing as a sign of peripheral cyanosis. Transthoracic echocardiography showed no intracard

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Fialho, I., M. Passos, J. Lima Lopes, et al. "Clinical and echocardiographic features of platypnea-orthodeoxia syndrome: a single-centre experience." European Heart Journal - Cardiovascular Imaging 23, Supplement_1 (2022). http://dx.doi.org/10.1093/ehjci/jeab289.317.

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Abstract Funding Acknowledgements Type of funding sources: None. Background Platypnea-orthodeoxia syndrome (POS) is an uncommon condition characterized by dyspnoea and hypoxemia in the upright position that improves with recumbency.1 Possible causes are intracardiac shunt, pulmonary arteriovenous shunt, and V/Q mismatch.1,2 Echocardiography is the cornerstone of POS diagnosis, with special focus on atrial septal defect (ASD) morphology and right-to-left shunt confirmation.3 Purpose To evaluate the clinical and echocardiographic features of patients presenting with POS due to a cardiac cause. M

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Lambden, Simon, Andrew S. Cowburn, David Macias, et al. "Endothelial cell regulation of systemic haemodynamics and metabolism acts through the HIF transcription factors." Intensive Care Medicine Experimental 9, no. 1 (2021). http://dx.doi.org/10.1186/s40635-021-00390-y.

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Abstract Background The vascular endothelium has important endocrine and paracrine roles, particularly in the regulation of vascular tone and immune function, and it has been implicated in the pathophysiology of a range of cardiovascular and inflammatory conditions. This study uses a series of transgenic murine models to explore for the first time the role of the hypoxia-inducible factors, HIF-1α and HIF-2α in the pulmonary and systemic circulations as potential regulators of systemic vascular function in normoxic or hypoxic conditions and in response to inflammatory stress. We developed a ser

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Ratish Chandra, G., Shyam Sundar. S, and Praveen Kumar Sindhur. "A STUDY OF POLYCYTHEMIA IN 34-41 WEEK SMALL FOR GESTATIONAL AGE(SGA) /INTRAUTERINE GROWTH RESTRICTED (IUGR) NEONATES." GLOBAL JOURNAL FOR RESEARCH ANALYSIS, March 15, 2023, 128–31. http://dx.doi.org/10.36106/gjra/7110023.

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Background: Polycythemia in neonates is dened by hematocrit value more than or equal to 65% on venous sample. Polycythemia is associated with hyperviscosity syndrome. In clinical setting,as it is not feasible to measure viscosity of blood, hematocrit value is used as a surrogatefor hyperviscosity. There is a need to evaluate the incidence of polycythemia in SGA babies as SGA is the commonest risk factor for PC followed by pregnancy induced hypertension (PIH) and infant of diabetic mother (IDM). Objectives: To estimate the incidence of polycythemia in 34 to 41week SGA/IUGR neonates and its rel

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Ogunsalu, Christopher. "The Physiological Basis Of The Oral Surgical Management Of A Patient With Polycythemia Rubra Vera: A Pathway For The Development Of A Protocol." Journal of Dentistry and Oral Sciences, February 1, 2022. http://dx.doi.org/10.37191/mapsci-2582-3736-4(1)-120.

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Various oral surgical procedures are currently performed under local anaesthesia and conscious sedation as a day surgery procedure. Both oral and intravenous conscious sedation are available as a choice. Oral sedation with Alprazolam and Codeine is very effective for most oral surgical procedures especially the removal of impacted third molars and surgical placement of implants. It is this sedation regimen that comprises the synergistic use of both aprazolam and codeine to effect sedation with amnesia that is the standard procedure at the Faculty of Dentistry of the International Postgraduate

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