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Journal articles on the topic 'Polyherbal Extract'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Lamba, Gagandeep, Nilima Thosar, and Pramod Khobragade. "Evaluation of the Antimicrobial efficacy of a novel polyherbal extract against Streptococcus Mutans: An in-vitro study." International Journal of Ayurvedic Medicine 13, no. 1 (2022): 101–5. http://dx.doi.org/10.47552/ijam.v13i1.2275.

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Aim: The present study was done to assess the antibacterial efficacy of a polyherbal extract against Streptococcus mutans (S. mutans) in-vitro. Materials and methods: In the current study, the ethanolic extracts of Haritaki, Bhibitak, Amalaki, Yashtimadhu, Haridra and Vacha were subjected to microbiological assay. The microbial growth inhibitory potential of the polyherbal extract was determined by using the agar disc diffusion method. Results: Mean zone of inhibition of polyherbal extract mix against S. mutans at 48 hours was 24mm. Minimum Inhibitory Concentration and Minimum Bactericidal Con

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Kota, Chaitanya Sravanthi, Chaitanya Sravanthi Kota, and Chaitanya Sravanthi Kota. "ACTIVITY OF POLYHERBAL EXTRACT AGAINST BACTERIA CAUSING SKIN INFECTIONS IN DIABETIC PATIENTS." Asian Journal of Pharmaceutical and Clinical Research 10, no. 5 (2017): 147. http://dx.doi.org/10.22159/ajpcr.2017.v10i5.17064.

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Objective : - The objective of this study is to evaluate antibacterial activity of Polyherbal extract on few microorganisms causing skin infections in most of the diabetic patients .Methods : - Methanolic Polyherbal extract was prepared from Acacia ferruginia (bark & fruit), Chloroxylon swietenia (bark, leaf, root), Casearia elliptica (bark), Terminalia alata (root, leaf). The preliminary phytochemical analysis was performed to identify the major phytoconstituents in the extract. Polyherbal extract was evaluated for antibacterial activity against bacteria like Staphylococcus aureus, Bacill

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Patil, Rahul N., Rohan R. Tarle, Snehal R. Somvanshi, Hemant V. Raut, Nitin B. Aher, and Prashant V. Vyavhare. "Pharmacological screening of anti-inflammatory potential of polyherbal extract." IP International Journal of Comprehensive and Advanced Pharmacology 9, no. 4 (2024): 270–74. http://dx.doi.org/10.18231/j.ijcaap.2024.039.

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Inflammation is the immune response to harmful stimuli, such as pathogens, damaged cells, toxic compounds, or irradiation and acts by removing injurious stimuli and initiating the healing process. Inflammation is therefore a defense mechanism that is vital to health. Usually, during acute inflammatory responses, cellular and molecular events and interactions efficiently minimize impending injury or infection. Current herbal medicine has been found effective with minimal or no side effect.Polyherbal extract of plants which contains curcumin, withanolides, withanoferins, linoleic acid are the ac

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Mani, Vadivel. "Phytochemical cocktail of Asanadi gana extract in the management of diabetes." Bioinformation 19, no. 3 (2023): 299–306. http://dx.doi.org/10.6026/97320630019299.

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It is of interest to investigate that the phytochemical analysis, in-vitro antioxidant potential and glycosidase inhibitory potential of Asanadi gana a polyherbal formulation. Asanadi gana is a classical Ayurvedic polyherbal formulation, markedly used for alleviation of Prameha and medodosha, which correlates in many ways with obesity, metabolic syndrome, and diabetes mellitus (madhumeha). The phytochemical constituents, total phenolic, total flavonoids, total tannin content, total antioxidant capacity, total reducing power, and free radical scavenging activity of the polyherbal formulation ex

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Jagtap, Pradnya, Yashashri Nimbalkar, Vidya Patil, and Ravindra Y. Patil. "In Vivo Antidiabetic Activities of Polyherbal Extracts against Streptozotocin- Nicotinamide Induced Type 2 Diabetic Mice Model." Tanzania Journal of Science 47, no. 3 (2021): 877–91. http://dx.doi.org/10.4314/tjs.v47i3.1.

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Diabetes mellitus is a chronic metabolic disorder and rapidly increasing cases of diabetes throughout the world are major concerns in both developed and developing countries. Currently available oral antidiabetic medicines have limitations in efficacy and safety, which in conjunction with the emergence of diabetes mellitus as a global epidemic have aided the popularity of alternative therapies to manage the disease safely and more efficiently. Herbal medicines are accepted as alternative therapies for blood sugar control. Gymnema sylvestre, Boerhavia diffusa, Tinospora cordifolia, and Argyreia

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Liyanagamage, Donisha Shani Niharika Keembiya, Susanthi Jayasinghe, Anoja Priyadarshani Attanayake, and Veranja Karunaratne. "Acute and Subchronic Toxicity Profile of a Polyherbal Drug Used in Sri Lankan Traditional Medicine." Evidence-Based Complementary and Alternative Medicine 2020 (July 13, 2020): 1–12. http://dx.doi.org/10.1155/2020/2189189.

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A polyherbal drug composed of leaves of Murraya koenigii L. Spreng, cloves of Allium sativum L., fruits of Garcinia quaesita Pierre, and seeds of Piper nigrum L. is a popular drug which has been used by indigenous practitioners in Sri Lanka for the treatment of diabetes mellitus and dyslipidemia. The acute toxicity assessment was conducted, following a single oral dose of 0.25–2.0 g/kg in healthy rats, and rats were observed up to 14 days. The hot water extract (1.0 g/kg) and the water : acetone extract (0.5, 1.0, and 1.5 g/kg) were administered to Wistar rats for 28 days in the subchronic stu

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Yogi, Bhumika, and Ashutosh Mishra. "HEPATOPROTECTIVE EFFECTS OF POLYHERBAL FORMULATION AGAINST CARBON TETRACHLORIDE-INDUCED HEPATIC INJURY IN ALBINO RATS: A TOXICITY SCREENING APPROACH." Asian Journal of Pharmaceutical and Clinical Research 10, no. 1 (2016): 192. http://dx.doi.org/10.22159/ajpcr.2017.v10i1.14757.

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ABSTRACTObjective: To investigate the hepatoprotective activity of aqueous methanolic extract of polyherbal formulation and individual extracts of Calotropisprocera, Gymnema sylvestre, and Lawsonia inermis leaves.Methods: The hepatoprotective activity of the formulation and extracts were assessed on the basis of histopathological changes in liver of carbontetrachloride-induced hepatotoxic rats.Results: The result of present studies strongly indicates that the hepatoprotective property of polyherbal formulation as evidenced by less damagedhepatocytes cells.Conclusion: Polyherbal formulation rev

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Arpit, Gawshinde*, Shrotriya Juliyas, Shaikh Azaruddin, Sharma Harshita, Meena Veerendra, and Singare Sajan. "FORMULATION AND EVALUATION OF POLYHERBAL ANTI-AGING CREAM." World Journal of Pharmaceutical Science and Research 4, no. 2 (2025): 1042–48. https://doi.org/10.5281/zenodo.15364822.

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Moringa oleifera family Moringaceae and Ocimum sanctum family Labiatae has been reported to possess antioxidant, antimicrobial, anti-inflammatory, antibacterial and antifungal properties. Moringa oleifera and Ocimum sanctum extracts have been used to treat antimicrobial infections. The aim of this present study is to formulate and evaluate of polyherbal anti-aging cream by combining the extract of Moringa oleifera with Ocimum sanctum to achieve multipurpose skin effects such as anti-aging, fairness, softening and antiseptic effects. The polyherbal anti-aging cream formulations comprising of hy

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Kankara, Sulaiman Sani, Maimuna Ahmad, and Umar Lawal. "ETHNOBOTANICAL SURVEY OF COSMETIC PLANTS USED IN KATSINA STATE, FORMULATION OF NATURAL POLY HERBAL LIGHTENING CREAM USING Curcuma longa AND Curcubita pepo EXTRACTS." FUDMA JOURNAL OF SCIENCES 7, no. 6 (2023): 313–27. http://dx.doi.org/10.33003/fjs-2023-0706-2133.

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This study aimed to conduct an ethnobotanical survey of cosmetic plants in Katsina State and formulate a polyherbal lightening cream using Curcuma longa and Cucurbita pepo extracts. The Research involved two main aspects. A semi-structured interview was used to gather information on the use cosmetic plants.23 plants were identified including: Aloe vera, Calatropis procera, Magnifera indica, Carica papaya,Allium cepa. These plants were found to have various cosmetic benefits such as skin lightening, weight loss, hair treatment, acne treatment. An attempt was made to formulate a safe lightening

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Molla, MR, MM Rahman, F. Akter, and M. Mostofa. "Effects of Nishyinda, black pepper and cinnamon extract as growth promoter in broilers." Bangladesh Veterinarian 29, no. 2 (2013): 69–77. http://dx.doi.org/10.3329/bvet.v29i2.14345.

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An extract of nishyinda (Vitex negundo) leaves, black pepper (Piper nigrum) and cinnamon (Cinnamomum verum) (polyherbal extract) were used as growth promoter in broilers. A total of 20 day-old broiler chicks were purchased and after seven days of acclimatization randomly divided into two equal groups. No vaccination schedule was practised and no antibiotics were added in rations. Group A served as control while group B was supplemented with polyherbal extract 1 mL/litre in drinking water. Weekly body weight gain up to six weeks was measured and blood tests were performed at 21 and 42 days. Pol

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Singh, Mahaveer, Desu Brahma Srinivasa Rao, Varinder Soni, PS Minhas, and S. Amudha. "Development and Evaluation of Polyherbal Gel for Treatment of Diabetic Neuropathy." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 165–68. http://dx.doi.org/10.25258/ijddt.14.1.23.

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Diabetic neuropathy is a prevalent and painful issue of diabetes mellitus, impacting a large number of people with both type 1 and 2 diabetes. Herbal formulations are found to be effective and have fewer side effects. The study aimed to create a topical polyherbal gel using ethanolic extracts and to evaluate polyherbal gel. Ethanolic extract of Curcuma longa rhizomes and Gingko biloba leaves were obtained and used to prepare different formulations of polyherbal gels using Carbopol 940 and other excipients. The developed compositions were assessed using a range of gel evaluation standards, incl

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Laware, Sandip G., and Nitin L. Shirole. "Formulation and Development of Polyherbal Ointment containing Clerodendrum serratum, Solanum xanthocarpum, and Nyctanthes arbortristis Extracts and Assessment of Anti-inflammatory Activity in Carrageenan-Induced Paw Edema Model." INTERNATIONAL JOURNAL OF PHARMACEUTICAL QUALITY ASSURANCE 14, no. 03 (2023): 523–28. http://dx.doi.org/10.25258/ijpqa.14.3.10.

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In this study, our objective was to explore the phytochemical constituents of Clerodendrum serratum (CS), Solanum xanthocarpum (SX), and Nyctanthes arbortristis (NA) and evaluate their anti-inflammatory activity. Subsequently, we aimed to develop a polyherbal ointment formulation incorporating these extracts. The phytochemical screening of the CS extract showed carbohydrates, steroids, terpenoids, flavonoids, saponins, and tannins. Similarly, the SX extract exhibited the presence of all these constituents, along with the additional presence of alkaloids. The NA extract demonstrated the presenc

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Parkhe, Geeta, and Deepak Bharti. "DEVELOPMENT AND EVALUATION OF ANTIDIABETIC POTENTIAL OF POLYHERBAL FORMULATION IN STREPTOZOTOCIN INDUCED ANIMAL MODEL." Journal of Advanced Scientific Research 13, no. 01 (2022): 181–87. http://dx.doi.org/10.55218/jasr.202213120.

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Vitex trifolia L, Vitex parviflora and Terminalia chebula are well-known plants available throughout India and are commonly used for the treatment of various diseases including diabetes mellitus. The antidiabetic activity of the individual plant parts is well known, but the synergistic or combined effects are unclear. The concept of polyherbalism has been highlighted in Sharangdhar Samhita, an Ayurvedic literature dating back to 1300 AD. Polyherbal formulations enhance the therapeutic action and reduce the concentrations of single herbs, thereby reducing adverse events. The aim of the present

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Dr., Bela Nabar*1 Neha Ailani2 Suhas Abhyankar3 Narendra Pendse4 Renu Jaisinghani5 Manju Lalwani Pathak6 Arvind Vartak7. "Evaluation Of Jamun-Based Polyherbal Formulations for Wound Healing By In Vitro Assays." International Journal of Pharmaceutical Sciences 3, no. 5 (2025): 4966–77. https://doi.org/10.5281/zenodo.15554773.

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Herbal formulations are effective in the control of infections, faster wound healing, and lower pain score for the patients. The current study involves four combination of plant extracts containing Jamun fruit extract as the common ingredient. The other plants used were fruits of Lavang, Amla, Hirda, and Beheda. Bark of Neem, Pipal & Betel leaves. The combinations prepared were hot aqueous extracts of Jamun, Lavang, Neem & Pipal. Hot alcoholic extracts of Amla, Beheda, Hirda, Jamun, Lavang & Neem, 50% cold alcoholic extract of Jamun, Amla, Hirda, Beheda, Lavang & cold alcoholic

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Basu, Nabamita, S. Rakesh, Rajesh Khanna Kotrike, Giriraj T. Kulkarni, and P. Veeresh Babu. "Formulation and Evaluation of Topical Poly Herbal Gel Consisting of Natural Antimicrobials for the Activity against Acne Vulgaris." Recent Trends in Pharmaceutical Sciences and Research 5, no. 2 (2023): 29–36. http://dx.doi.org/10.46610/rtpscr.2023.v05i02.005.

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The purpose of this research paper is to find out which effective antibacterial substances are in different herbs and their use in acne vulgaris and hyperpigmentation. Herbal gel with four herbs mainly including Azadiracta indica, Hibiscus rosa sinesis, Piper Betle and Aloe barbadensis was formulated with a base gel. Two formulations were prepared and evaluated for pH, dispersibility, detergency, and zone of inhibition. Preliminary phytochemical evaluations of the extracts were performed according to the standard procedures. Later antimicrobial activity of the individual extracts and polyherba

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Saniya Begum, J. Selvaraj, V. Ranganathan, and N. Babu Prasath. "EFFECT OF STREPTOZOTOCIN AND POLYHERBAL EXTRACT ON BIOCHEMICAL PARAMETERS IN WISTAR RATS." Indian Journal of Veterinary and Animal Sciences Research 53, no. 5 (2025): 89–94. https://doi.org/10.56093/ijvasr.v53i5.162260.

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Gymnema sylvestre, Annona muricata and Ocimum sanctum are well known plants available in India and they are commonly used for the treatment of various diseases including diabetes mellitus. A study was conducted to assess the hypoglycemic effect of a polyherbal extract containing these plants (at two different doses of300 and 600 mg/kg bwt) compared with metformin as a standard hypoglycemic drug at a dose of 100 mg/kg bwt in streptozotocin-induced diabetes in rats. As a part of the study, the effect of the polyherbal extract on the renal and hepatic functions was tested in rats. The serum param

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Patil, Shrutika Arun, and Supriya Panhale. "Preparation and Evaluation of Polyherbal Gel by Using Wheatgrass and Cucumber Extract." International Journal for Research in Applied Science and Engineering Technology 13, no. 5 (2025): 7512–23. https://doi.org/10.22214/ijraset.2025.71902.

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Abstract: The increasing global interest in natural sources of bioactive compounds has significantly spurred research into the phytochemicalprofilesofvariousmedicinalplants.Topicalpreparations,designedforexternaluse,serveasaneffectivemeansfor both skinprotection and treatment, with diverse formulations such as creams, ointments, and gels available. This study aimed to prepare and evaluate a polyherbal topical gel utilizing ethanolic extracts of wheatgrass (Triticum aestivum) leaf and cucumber (Cucumissativus)fruit,bothrenownedfortheirnutritionalandtherapeuticpotential.Theplantmaterialswereauth

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SASIDHARAN, M. "IN VITRO ANALYSIS OF ANTIOXIDANT ACTIVITY IN POLYHERBAL PLANT EXTRACT." YMER Digital 21, no. 05 (2022): 1499–514. http://dx.doi.org/10.37896/ymer21.05/g4.

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Most plants are considered to prevent free radicals associated damages by numerous ways including direct scavenging of free radicals and inhibition of enzymes involved in free radical production. The aim of the present study was to examine the antioxidant activities of the hexane from polyherbal plants of Carica papaya, Punica granatum, Catharanthus roseus and Cympbopogan citratus which is long been known to be a very important source of pharmaceutical. Different concentrations of polyherbal extract was tested for anti-oxidant properties using hydrogen peroxide assay. Similarly, the free radic

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CHAUHAN, AMISHA, and SHIKHA BAGHEL CHAUHAN. "FORMULATION AND EVALUATION OF POLYHERBAL EMULGEL FOR TREATMENT OF ACNE." Current Research in Pharmaceutical Sciences 12, no. 3 (2022): 132–37. http://dx.doi.org/10.24092/crps.2022.120302.

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Skin disease is a persistent inflammatory skin disorder that affects around 70% of teenage females throughout puberty. To counteract this problem, antibiotics are being administered more often, which has resulted in a variety of undesirable side effects. As a result, as a first-line topical therapy, it must target on the herbal formulation. In this study, medicinal plant extracts and oils with high antibacterial activity, such as Curcuma longa and Aloe barbadensis, tea tree oil, and lemongrass oil, were chosen to produce a polyherbal emulgel for the treatment of acne vulgaris. Curcuma longa, A

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Amujoyegbe, O. O., M. Idu, J. M. Agbedahunsi, and G. N. Bazuaye. "In vitro evaluation of antisickling activity of herbal combination of three medicinal plants." Nigerian Journal of Natural Products and Medicine 23 (May 13, 2020): 54–62. http://dx.doi.org/10.4314/njnpm.v23i1.7.

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Sickle cell disorder is a genetic ailment with enormous social and economic burden for patients and caregivers. The most promising management apart from being expensive particularly for poor African people, faces some major incompatibility problems. The patients consequently rely on herbal therapy which could be prepared in single or combination forms to manage the painful episodes and its complications. This present study aimed to formulate polyherbal combination and evaluate three purposively selected plants previously reported for their antisickling activities. The polyherbal products were

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Mussarat, Sakina, Muhammad Adnan, Shaheen Begum, Alamgeer, Riaz Ullah, and Alicja Kowalczyk. "In Vivo Efficacy, Toxicity Assessment, and Elemental Analysis of Traditionally Used Polyherbal Recipe for Diarrhea." Evidence-Based Complementary and Alternative Medicine 2022 (August 22, 2022): 1–11. http://dx.doi.org/10.1155/2022/5977795.

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A polyherbal formulation consisting of Mentha piperita L., Camellia sinensis L. Kuntze, and Elettaria cardamomum (L.) Maton with a ratio of 10 : 5 : 2, respectively, was recommended for curing nausea, vomiting, and diarrhea. Experimental validation is crucial to affirm its therapeutic property leads toward the development of modified antidiarrheal agents. This research aimed to investigate the in vivo antidiarrheal efficacy of traditionally used polyherbal recipe in a castor oil-induced animal model. Moreover, the study also presents the elemental screening and in vivo toxicity of tested polyh

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Balakrishnaiah, P., and T. Satyanarayana. "Preparation and evaluation of polyherbal formulation for its antidiabetic activity against streptozotocin induced diabetes rat model." Pharmaceutical and Biological Evaluations 4, no. 2 (2017): 111. http://dx.doi.org/10.26510/2394-0859.pbe.2017.17.

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Objective: The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus using streptozotocin in normal Albino wistar rats and study the antdiabetic activity of polyherbal formulation by comparison of changes in levels of glucose between normal and diabetic rats.Methods: The effect of methanol extract of poly herbal preparation containing aerial parts of Schrebera swietenoides, roots of Barleria montana and aerial parts of Rotula aquatica was investigated in normal and streptozotocin indu

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Prashant, Purohit, and Kumar Kataria Mahesh. "Formulation and Evaluation of Polyherbal Ointment Using Carica Papaya and Leptadenia Pyrotechnica." International Journal of Current Pharmaceutical Review and Research 16, no. 05 (2024): 22–27. https://doi.org/10.5281/zenodo.12784911.

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AbstractThe foundation of the herbal medication business is the ethnomedical values of plants. In order to create herbalmedications with minimal side effects, India has contributed its expertise in traditional system medicines (Ayurvedaand Siddha). These plants have historically been utilized by tribal communities in India as extracts, powders, orpastes to cure conditions including anti- microbial activity, cough and colds, fever, stomach, kidney, and liverdiseases, pain, inflammation, and wounds. According to WHO data, plant extracts are used to treat more than 80%of the world's population fo

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K, Mekala, Shaheedha SM, and Prakash R. "Impact of Nanoethosomes Loaded with Polyherbal Extracts on the Mechanisms Involved in Wound Healing In-vitro Research." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 03 (2024): 1334–43. http://dx.doi.org/10.25258/ijddt.14.3.12.

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This study focuses on formulating and optimizing Polyherbal Nanoethosomes for controlled drug delivery, utilizing a polyherbal extract comprising Basella alba L., Portulaca oleracea L., Lawsonia inermis L., Trigonella foenum L., and Peristrophe paniculata L. Comprehensive characterization revealed a variety of secondary metabolites within the extract. The primary goal was to create poly herbal extract-entrapped ethosomes that could be integrated into a sustained-release transdermal gel dosage. We prepared nanoethosomes using phosphatidylcholine, ethanol, Tween 80, and SLS, and optimized them u

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Kaur, Navjot, Rahul Kumar Sharma, Baljeet Singh, Navdeep Kaur, and Shailesh Sharma. "A Polyherbal extract treats Streptozotocin induced Diabetes mellitus: Pharmacognostic study, HPLC analysis and in vivo antidiabetic activity." International Journal of Ayurvedic Medicine 15, no. 1 (2024): 160–71. http://dx.doi.org/10.47552/ijam.v15i1.4257.

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The plants used in study have been used traditionally for various purposes skin problems, diabetes, astringent, anti-inflammatory, antioxidant, hepatoprotective activities, anthelmintic, antipyretic, antidysentric, anti-hyperlipidemic, anticancer properties. The present study involves the evaluation of pharmacognostic parameters of the four herbal drugs (Azadirachta indica leaves, Pterocarpus marsupium heartwood, Picrorhiza kurroa rhizomes, and Withania coagulans berries and fruit coat), High performance Liquid chromatography (HPLC) as well as antidiabetic activity of polyherbal extract. The q

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Nayak, Sachin, Kirankumar GD, Vikesh ., Pradyumna B, and Sandeshraj . "FORMULATION AND EVALUATION OF HERBAL TOOTHPASTE." Journal of Biological & Scientific Opinion 12, no. 5 (2024): 54–59. http://dx.doi.org/10.7897/2321-6328.12598.

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The present study is concerned with the formulation and evaluation of herbal toothpaste, which contains various properties like tooth abrasives, tooth whitening, anti-caring, antibacterial, anti-inflammatory, desensitivity, etc. The herbal toothpaste was prepared using mango leaf extract and guava leaf extract as active ingredients, along with various excipients, which include calcium carbonate, sodium chloride, sodium lauryl sulphate, sodium benzoate, glycerine, camphor, honey and distilled water. The toothpaste was prepared by homogeneous mixing of all the excipients and the herbal extract.

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Kangara, K. M. T. D. B., N. W. A. N. Maanisha, D. B. M. Wickramaratne, and H. H. V. K. N. De Silva. "<em>In vitro</em> synergistic evaluation of tyrosinase inhibition and antioxidant activities of <em>Mimosa pudica</em> and <em>Glycyrrhiza glabra</em> plant extracts for the treatment of hyperpigmentation." Pharmaceutical Journal of Sri Lanka 14, no. 1 (2024): 11–18. https://doi.org/10.4038/pjsl.v14i1.98.

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Purpose: This study aimed to evaluate the tyrosinase inhibitory activity of a combination of Mimosa pudica and Glycyrrhiza glabra extracts to explore potential synergistic effects and to assess the antioxidant activity of the individual extracts. The findings support the development of a polyherbal topical formulation for hyperpigmentation treatment. Methods: The ethanolic extract of G. glabra roots was obtained via reflux condensation at 60°C, while the methanolic extracts of M. pudica leaves and seeds were prepared at 50°C. The mushroom tyrosinase inhibition assay and 2,2-diphenyl-1-picrylhy

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Santoso, Joko, and Heru Nurcahyo. "FORMULASI EKTSTRAK POLIHERBAL KOMBINASI EKSTRAK TULANG CEKER AYAM TERHADAP BAKTERI STAPILOCOCUS AUREUS." Jurnal Ilmiah Manuntung 5, no. 2 (2020): 183. http://dx.doi.org/10.51352/jim.v5i2.279.

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The development of traditional plants as herbal medicines continues to be increased, especially in local use. Aloe vera (Aloe vera), bay leaf (Eugenia polyantha) and Turmeric Rhizome (Curcuma domestica Val) have compounds that function as antibacterial. Chicken claw bones play a role in accelerating the growth of skin cells, but it also has the potential as an antibacterial. This combination is expected to increase the work of medicinal ingredients in killing bacteria. The work method begins with the selection of herbal ingredients, dry sorting, wet sorting and slicing. Drying the sample using

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S.R., Somvanshi, Talware P.R., Gaikwad Y.S., Patil R.N., and Vyavhare P.V. "PRECLINICAL EVALUATION OF POLYHERBAL AS AN ANTI- ALZHEIMERS, BY USING IN-VITRO ANTICHOLINESTERASE ENZYME MODEL." International Journal of Advanced Research 12, no. 09 (2024): 1179–91. http://dx.doi.org/10.21474/ijar01/19551.

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Background: Alzheimers disease is a neurodegenerative brain condition that causes mild cognitive impairment and memory loss, eventually leading to dementia. With developments in medicine, there are now more people in the world trying to treat a wider range of illnesses. It has been discovered that traditional herbal treatment works well with little or no adverse effects. Materials & Methods: There are certain chemical components in the polyherbal extract of liquorice, ginger, and hibiscus sabadariffa that have anti-Alzheimers properties. Results & Discussion: The polyherbal extract of

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Rao, NG Raghavendra, Desu Brahma Srinivasa Rao, Parag A. Kulkarni, Dhruv Dev, and G. Santhana Kumar. "Preparation and Evaluation of Polyherbal Periodontal Gel for Treatment of Periodontitis." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 14, no. 01 (2024): 179–82. http://dx.doi.org/10.25258/ijddt.14.1.26.

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Periodontal disease is one of the most important concerns for dentists and patients. The study aimed to create a topical polyherbal gel using ethanolic extract and to evaluate polyherbal gel. Ethanolic extract of Curcuma longa rhizomes, chamomile powder from Matricaria chamomilla, and clove oil were obtained and used to prepare different formulations of polyherbal gels using hydroxypropyl methylcellulose (HPMC) and other excipients. The prepared gel formulations were studied for pH, viscosity and spreadability evaluation. The pH was observed to be in between 6 to 7 and had ideal viscosity and

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A.W., Baitule, M.G. Tawar Dr., and S.D. Pande Dr. "Antiinflammatory Activity of Polyherbal Gel Formulation." International Journal of Current Science Research and Review 06, no. 03 (2023): 1883–86. https://doi.org/10.5281/zenodo.7695515.

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  <strong>ABSTRACT: </strong>The present study has been undertaken with the aim to formulate and evaluate the new polyherbal gel formulation containing 0.3 % hydroalcoholic  extract from Trigonellafoenum-graecum and Glycyrrhiza glabra for its topical anti inflammatory activity against carrageenan induced rat paw edema method .The studies were conducted on Wistar rats of either sex (150-180g).The polyherbal gel formulation was designed by using Carbopol 934, Sodium CMC, Trigonellafoenum-graecum, Glycyrrhizaglabra  extract, Ethanol, propylene glycol 400,  methyl paraben, prop

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Deepak, Jain, and Jain Anurekha. "DEVELOPMENT OF POLYHERBAL WITH ANTIOXIDANT ACTIVITY." Asian Journal of Pharmaceutical and Clinical Research 11, no. 8 (2018): 483. http://dx.doi.org/10.22159/ajpcr.2018.v11i8.27791.

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Objective: The objective of this research was to develop a polyherbal formulation (PHF) using four different herbs and to evaluate their phytochemicals, physical constants, and determination of their antioxidant activity by DPPH method.Methods: The PHF authenticated herbs were characterized by studying its morphological and pharmacognostic characters. Phytochemical screening showed the presence of alkaloids, glycosides, carbohydrates, amino acid, tannin, steroids, and flavonoids in the combination extract. Physical parameters such as loss on drying (LOD), pH, ash values, LOD, and extractive va

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Bhat, Vishnu, Ravi Kumar, Azeena ., Farnaaz Baji Siraj, Lamiya Raja, and Sandeep Kumar Jain. "FORMULATION AND EVALUATION OF POLYHERBAL SHAMPOO CONTAINING EXTRACT OF HIBISCUS, HOLY BASIL AND FENUGREEK." International Research Journal of Pharmacy 12, no. 12 (2022): 27–29. http://dx.doi.org/10.7897/2230-8407.1212175.

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Shampoos has primarily been products that are intended to cleanse the hair and scalp. Herbal preparations always functional and have good activity and very minimal or no adverse effects on performance with synthetic. This study intended to prepare/ formulate and evaluate a complete herbal shampoo containing plant materials used only traditionally. The herbal shampoo prepared containing aqueous extracts of petals of Hibiscus (Hibiscus rosa-sinensis), leaves of Holy basil (Ocimum tenuiflorum) and dried leaves of Fenugreek (Trigonella foenum graecum) prepared by decoction method individually. Var

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Nyakayo A., Omutindo. "Polyherbal Extracts and Hormonal Crosstalk in Male and Female Fertility: Advances in Natural Endocrine Modulation." RESEARCH INVENTION JOURNAL OF RESEARCH IN MEDICAL SCIENCES 4, no. 3 (2025): 83–87. https://doi.org/10.59298/rijrms/2025/438387.

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Hormonal balance plays a pivotal role in regulating fertility in both sexes, orchestrated through intricate crosstalk between hypothalamic, pituitary, and gonadal hormones. Dysregulation in this hormonal network underlies many reproductive disorders, including polycystic ovary syndrome (PCOS), hypogonadism, infertility, and irregular menstrual cycles. While conventional hormonal therapies offer targeted intervention, they are often accompanied by side effects and long-term safety concerns. Increasingly, attention is turning to polyherbal extract combinations of multiple medicinal plants known

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P. Manorama, Valmiki Aruna, D. Geetha, and Gangadhara Angajala. "HPLC PROFILING AND ANTIHYPERGLYCEMIC EVALUATION OF PHE (POLYHERBAL EXTRACT) OF SELECTED INDIAN MEDICINAL HERBS IN ALLOXAN DIABETIC RATS." RASAYAN Journal of Chemistry 15, no. 04 (2022): 2576–83. http://dx.doi.org/10.31788/rjc.2022.1546498.

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In the present work antihyperglycemic screening of the polyherbal powder was carried out by oral administration of an aqueous extract of polyherbal powder on alloxan-induced diabetic rats. The polyherbal powder displayed a substantial increase in hypoglycemic efficacy at a dose of 100 mg/kg and 200 mg/kg in both Alloxan-induced diabetic rats and normal rats. The powder also exhibited enhancement in various parameters like the glycogen content of the liver, restoration of pancreatic β-cells, body weight, and carbohydrate metabolizing enzymes. Results obtained showed that the Alloxan diabetic ra

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Bhaskarrao, Pande V., Chandel S. Singh, and Soni Vishal. "Novel Antidiabetic Polyherbal Formulation for Synergistic Therapeutic Effects in Streptozotocin (STZ)-Induced Diabetic Rats." INTERNATIONAL JOURNAL OF DRUG DELIVERY TECHNOLOGY 12, no. 04 (2022): 1612–17. http://dx.doi.org/10.25258/ijddt.12.4.23.

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Worldwide demand for new anti-diabetic drugs from plant sources has increased as diabetes mellitus has become a global epidemic. In the era of herbal medicines, polyherbal formulations offer higher therapeutic efficacy than single plants due to synergistic effects. Therefore, the objective was to develop a novel anti-diabetic polyherbal formulation containing mixtures of three plants: Azadirachta indica leaves, Tinospora cordifolia stem and Ocimum sanctum leaves extracts. The eight different plant formulations (F1 to F8) were formulated while F1 to F3 contained a single plant extract. Hypergly

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Amujoyegbe, O. O., M. Idu, J. M. Agbedahunsi, et al. "Acute and sub-acute toxicity of antisickling polyherbal extract in Wistar albino rats." Nigerian Journal of Natural Products and Medicine 23 (May 13, 2020): 41–53. http://dx.doi.org/10.4314/njnpm.v23i1.6.

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Piper guineense, Gongronema latifolium and Cymbopogon citratus (PGC) serve as an effective polyherbal antisickling extract used in the management of sickle cell disorder. This present study assessed the toxicity effect of the ethanol leaf extract of PGC in rats. The acute oral toxicity test of the polyherbal was evaluated in albino rats using a single-dose based on behavioral changes and mortality. Sub-acute toxicological evaluation of PGC was examined using biochemical, hematological and histopathological methods. Biochemical analysis was carried out using liver markers enzymes, kidney marker

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Bhawar, Sanjay B., Santosh B. Dighe, and Rutuja B. Tambe. "Formulation and Evaluation of Polyherbal Ointment for Wound Healing and Antimicrobial Activity." Journal of Drug Delivery and Therapeutics 9, no. 3-s (2019): 575–82. http://dx.doi.org/10.22270/jddt.v9i3-s.2917.

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Herbal therapy and herbal drugs predominates in traditional medicine as well as in alternative medicine practiced in the developed world. Among the various indications where traditional herbal medicines are used, skin related disorders is ranked top. Thus, the main objective of the present study is to formulate and evaluate a polyherbal ointment for wound healing and antimicrobial activity. Ointments were formulated using hydroalcoholic extracts (soxhlet extraction) of Piper nigrum and Curcuma longa were evaluated for its physicochemical property, wound healing and antimicrobial activity. Oint

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Mapeka, Tsholofelo, Maxleene Sandasi, Alvaro Viljoen, and Sandy van Vuuren. "Optimization of Antioxidant Synergy in a Polyherbal Combination by Experimental Design." Molecules 27, no. 13 (2022): 4196. http://dx.doi.org/10.3390/molecules27134196.

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Culinary herbs and spices are known to be good sources of natural antioxidants. Although the antioxidant effects of individual culinary herbs and spices are widely reported, little is known about their effects when used in combination. The current study was therefore undertaken to compare the antioxidant effects of crude extracts and essential oils of some common culinary herbs and spices in various combinations. The antioxidant interactions of 1:1 combinations of the most active individual extracts and essential oils were investigated as well as the optimization of various ratios using the de

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Nagja, Tripathi, Vimal Kumar, and Acharya Sanjeev. "Anti-Diabetic Activity of a Polyherbal Formulation in Streptozotocin Induced Type 2 Diabetic Rats." Journal of Natural Remedies 16, no. 4 (2017): 148. http://dx.doi.org/10.18311/jnr/2016/15323.

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The aim of the present study was to determine the anti-diabetic activity of a polyherbal formulation in streptozotocin induced type 2 diabetic rats. The hydroalcoholic extracts of Eugenia jambolana, Gymnema sylvestre, Momordica charantia and Andrographis paniculata and sodhana processed extract of Myristica fragrans were prepared. The 2 day old neonatal rats were injected with 90 mg/kg of streptozotocin intraperitoneally to induce type 2 diabetes. After six weeks of streptozotocin injection, polyherbal formulation was daily administered at a dose of 400 mg/kg body weight to diabetic rats for a

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Qaragholi, Zena M., Ahmed Rahmah Abu Raghif, and Enas Jawad Kadhim. "Antiaging Effects of a Poly Herbal Extract in Comparison with Vitamin E on Aging Induced Mice." Pakistan Journal of Medical and Health Sciences 16, no. 4 (2022): 445–48. http://dx.doi.org/10.53350/pjmhs22164445.

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Background: Herbal medicine has been used from antient times to defy aging as cleopatra used several herbs as a drink or topically and pomegranate was a main herb used in her system, it was named the fruit of immortality. Combining three herbs into one preparation is recommended to increase medicinal benefits while reducing toxicity and to obtain a synergistic effect. In this study we have found that a polyherbal (Apium graveolens, Carthamus tinctorius, Punica granatum) extract from Iraqi origin have gave a stronger effect than vitamin E. Aim: The aim of this study was to evaluate the effect o

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Chandra, Shekar B. R., Ramesh Nagarajappa, Richa Jain, S. Suma, K. Mruthunjaya, and Rupesh Thakur. "Evaluating the Antimicrobial Efficacy of an Innovative, Novel Herbal Formulation on Dental Caries and Plaque Microorganisms - A Clinical Research." Biomedical and Pharmacology Journal 12, no. 04 (2019): 1633–45. http://dx.doi.org/10.13005/bpj/1794.

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To develop a novel, innovative herbal formulation that can prevent both dental caries and periodontal diseases simultaneously. This clinical research involved in vitro studies to determine Minimum Inhibitory Concentration (MIC) of combinations of Acacia nilotica, Murraya koenigii Linn Sprengel, Eucalyptus hybrid, and Psidium Guajava on dental caries and plaque bacteria followed by evaluation of phytochemical constituents in these plant extracts. MIC was determined using broth dilution method. Then, an animal experimentation was carried out to determine median lethal dose and adverse drug react

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Dhiya Shoufi Sahaja, Aura Nasyafa, and Nor Latifah. "FORMULASI DAN EVALUASI STABILITAS TIGA SEDIAAN HERBAL CAIR: SIRUP POLIHERBAL, FOOT SANITIZER, DAN FACE SPRAY." Jurnal Riset Multidisiplin Edukasi 2, no. 7 (2025): 9–16. https://doi.org/10.71282/jurmie.v2i7.615.

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This study presents an in-depth review of three journals focusing on the formulation, evaluation, and stability of polyherbal syrup preparations containing extracts of Moringa oleifera (drumstick leaves), Curcuma longa (turmeric rhizome), and Zingiber officinale (ginger rhizome). The polyherbal syrup is known for its strong antioxidant activity, with potential benefits as an immunomodulator and protection against degenerative diseases. The primary study emphasized physical stability testing through accelerated stability studies at 40°C ± 2°C and 75% ± 5% relative humidity for three months, usi

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N., Muthu Lakshmi* Dr. A. Dhinek. "Exploring the Synergistic potential of Polyherbal Extracts in Enhancing Antimicrobial and Antioxidant Activities." International Journal of Pharmaceutical Sciences 3, no. 3 (2025): 1077–84. https://doi.org/10.5281/zenodo.15015101.

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Polyherbal formulations have gained significant interest due to their synergistic effects and therapeutic potential. This study aims to evaluate the phytochemical composition, antioxidant capacity, and antimicrobial activity of a polyherbal extract containing <em>Morinda pubescens, Terminalia catappa, and Tridax procumbens</em>. A qualitative phytochemical screening was performed to detect the presence of bioactive compounds, including flavonoids, phenolics, alkaloids, tannins, and saponins. The antioxidant activity was assessed through established <em>in vitro</em> assays, such as the DPPH (2

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Olabinri, Patience F., Tolulope A. Oyedeji, Tope T. Odunitan, Oluwatosin F. Agunbi-ade, Leonard O. Ehigie, and Adeola F. Ehigie. "Phytochemical Screening, Ftir and Gas Chromatography-Mass Spectroscopy Analysis of Methanol Extract of a Polyherbal Mixture." Pan African Journal of Life Sciences 9, no. 1 (2025): 329–38. https://doi.org/10.36108/pajols/5202/90.0130.

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Background: Secondary metabolites are naturally occurring substances produced by plants that exhibit a variety of biologi-cal functions. This study aimed to identify the phytochemicals and functional groups present in a polyherbal mixture com-posed of Ageratum conyzoides leaves, Xylopia aethiopica fruit, Lepidium meyenii roots, and Hunteria umbellata seeds. Methods: The plant materials were collected, ground together, air-dried, and then pulverized into a fine powder. A total of 500 grams of the polyherbal mixture was soaked using methanol as the solvent. The extract was filtered and then subj

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Bakshi, Vasudha, K. Sharath Kumar, Nazia Begum, and Rahul M. Kakalij. "Neuroprotective Activity of Ethanolic Extract of Polyherbal Formulation on Streptozotocin Induced Alzheimer’s Disease in Mice." INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH 1, no. 01 (2016): 1–7. http://dx.doi.org/10.21477/ijapsr.v1i1.9602.

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Objective: To investigate the effect of Polyherbal Formulation on cholinergic dysfunction in STZ induced Alzheimer‟s disease (AD). Methodoloy: The current study was designed to investigate the protective effect of Polyherbal Formulation (PHF) 200 and 400mg/kg for 21days. Swiss albino mice were injected with STZ (0.5mg/kg) on 14th day of pretreatment with PHF. Behavior pattern was assessed using Morris water maze, Y maze and Open field test. Biochemical estimations, namely brain Acetylcholinesterase (AchE), reduced glutathione (GSH), Catalase, Super oxide dismutase (SOD) and TBARS levels were p

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Paul, Souvik, Tanmoy Dey, Prabin Koirala, Sidhant Tamang, Soumik Bhattacharya, and Rajat Das. "Formulation and evaluation of Polyherbal tablet by using Neem, Tulsi, Turmeric and Ginger extract." Journal of Drug Delivery and Therapeutics 13, no. 7 (2023): 46–51. http://dx.doi.org/10.22270/jddt.v13i7.5895.

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Introduction: Cold and cough is the common disease condition which effects patient of every age. The treatment approach of medicinal herbs has been recognized for many decades and even longer for the treatment and prevention of cold and cough. The aim of the study was to evaluate the safety and efficacy of polyherbal tablet. Polyherbal tablet containing herbs like Neem (Azadirachta indica), Tulsi (Ocimum tenuiflorum), Ginger (Zingiber officinale), Turmeric (Curcuma longa) is used for curing cold and cough. This tablet formulation reduces the healing time for sore throat and boost up the immuni

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Rao, T. J. Mohan, and Margret Chandira. "Study on Antioxidant Activity of Three Ethanolic Extract Polyherbal Formulation." International Journal of Pharma Research and Health Sciences 8, no. 3 (2020): 3155–60. http://dx.doi.org/10.21276/ijprhs.2020.03.01.

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Aslam, Muhammad Shahzad, Muhammad Syarhabil Ahmad, Awang Soh Mamat, Muhammad Zamharir Ahmad, and Faridah Salam. "Antioxidant and Wound Healing Activity of Polyherbal Fractions ofClinacanthus nutansandElephantopus scaber." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–14. http://dx.doi.org/10.1155/2016/4685246.

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Elephantopus scaberandClinacanthus nutansare traditionally used as wound healing herb. The objective of the present study is to develop a new polyherbal formulation, by comparison, the herbal combination ofElephantopus scaberandClinacanthus nutansas an in vitro antioxidant activity with their individual herbal activity followed by fractionation of polyherbal formulation for in vivo wound healing activities and identification of bioactive compounds from their active fractions. Antioxidant activity was performed in vitro by DPPH scavenging antioxidant activity followed by in vivo wound healing a

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Wang, Xin, Yufeng Jin, Can Di, et al. "Supplementation of Silymarin Alone or in Combination with Salvianolic Acids B and Puerarin Regulates Gut Microbiota and Its Metabolism to Improve High-Fat Diet-Induced NAFLD in Mice." Nutrients 16, no. 8 (2024): 1169. http://dx.doi.org/10.3390/nu16081169.

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Silymarin, salvianolic acids B, and puerarin were considered healthy food agents with tremendous potential to ameliorate non-alcoholic fatty liver disease (NAFLD). However, the mechanisms by which they interact with gut microbiota to exert benefits are largely unknown. After 8 weeks of NAFLD modeling, C57BL/6J mice were randomly divided into five groups and fed a normal diet, high-fat diet (HFD), or HFD supplemented with a medium or high dose of Silybum marianum extract contained silymarin or polyherbal extract contained silymarin, salvianolic acids B, and puerarin for 16 weeks, respectively.

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