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Zulfiqar, Maryam, M. Imran Hasan Khan, Salman Shakeel, and Farhat Naz. "POLYHYDRAMNIOS." Professional Medical Journal 25, no. 11 (2018): 1759–65. http://dx.doi.org/10.29309/tpmj/18.4745.
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Background: Polyhydramnios is a condition characterized by excessiveamniotic fluid around the baby. The most widespread causes of severe Polyhydramnios are fetalanomalies often linked with a primary genetic anomaly. However, gestational diabetes, multiplepregnancies and idiopathic factors are commonly related with milder cases. So, we designedthis study to see the association of polyhydramnios and perinatal outcome. Objectives: Tocompare the Perinatal outcomes in patients with explained and unexplained Polyhydramnios.Study Design: Cohort study. Setting: Obstetrics & Gynaecology Department and Diabetesclinic of Postgraduate Medical Institute, Lahore General Hospital. Period: 6 months From Jan2014 to June 2014. Material & Methods: 300 females were included through Non probabilitypurposive sampling. Informed consent and Demographic history was recorded. The patientswere divided into two groups. Those having congenital anomalies and diabetes mellitusdetermined by ultrasonography and laboratory investigations were included in Group ‘I’ andpatients with no detectable cause of polyhydramnios were included in Group ‘II’. All the data wasrecorded in well-defined proforma. Data was entered and analyzed through SPSS 20. Relativerisk was calculated to see any association between perinatal outcomes in both study groups.RR > 1 was considered as statistically significant. Results: The mean age of the patients wasnoted as 29.37±5.37 years. The mean gestational age was noted as 34.82±2.09 weeks. In thisstudy, Macrosomia was observed in 60 (20%) cases whereas Malpresentation was observedin 51 (17%) cases. Malpresentation was observed in 51 patients out of which 14 (27.5%) werefrom explained Polyhydramnios and 37 (72.5%) were from unexplained Polyhydramnios group.Statistically there is significant difference between the study groups i.e. RR=3.181. Macrosomiawas observed in 60 patients out of which 18 (30%) were from explained Polyhydramnios groupand 42 (70%) were from unexplained Polyhydramnios group. Statistically there is significantdifference between the study groups i.e. RR=2.852. Conclusion: It was concluded throughresults of this study that unexplained Polyhydramnios has more risk of developing adverseperinatal outcome.
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TARIQ, SAADIA, SADIA CHEEMA, ADEELA AHMAD, and Naela Tarique. "POLYHYDRAMNIOS." Professional Medical Journal 17, no. 04 (2010): 660–64. http://dx.doi.org/10.29309/tpmj/2010.17.04.3017.
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Polyhydramnios is though an uncommon problem but very distressing for patient. Objectives: To locate the causative factors and neonatal outcome in polyhydramnios. Design: Case series. Setting: Department of Obstetrics and Gynaecology unit 1, Lahore General Hospital, Lahore. Period: From January 2004- December 2005. Subjects and Methods: Total 82 diagnosed cases of polyhydramnios in 3rd trimester were included in this study. Results: According to the results of this study polyhydramnios can occur in primigravida as well asmultigravida. Causative factor are mainly idiopathic after which the most important is fetal defects. Diabetes is also associated finding with polyhydramnios in 26.8% cases. The impact of polyhydramnios on neonatal outcome is that most of the babies were born without any significant effect. There were only 26 babies (31.5%) in which anomalies were present and neural tube defects were common. Conclusions: Idiopathicpolyhydramnio being the most common type. Improved prenatal and antenatal screening and early detection of congenital anomalies may help to minimize the morbidity of the patient.
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Qadir, Maimoona, and Sohail Amir. "POLYHYDRAMNIOS;." Professional Medical Journal 24, no. 12 (2017): 1889–93. http://dx.doi.org/10.29309/tpmj/2017.24.12.606.
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Background: Polyhydramnios is an obstetrical condition associated withsignificant perinatal and maternal morbidity and mortality. Although it is uncommon conditionbut a source of much discomfort to the patient. Objectives: To determine the maternal andfetal outcome of Polyhydramnios. Study Design: Descriptive cross sectional study. Setting:Gynaecology and Obstetrics Department of Khyber Teaching Hospital, Peshawar. Period: 1stJanuary 2016 to 31st December 2016. Methodology: All the cases diagnosed as polyhydramniosaccording to amniotic fluid index in four pockets, in women of any age or parity after 20 weeksgestation were included. Results: Incidence of polyhydramnios was 1.8%.170(61%) caseswere in age range of 31- 40 years and 137(49%) were multigravidas. 162(58%) cases had mildpolyhydramnios. Pre ecclampsia was the commonest maternal condition associated in 42(15%)cases followed by anemia in 39(13.97%) and diabetes in 28(10%) cases. Complications thatoccurred as a result were preterm labor in 33(11.8%), premature rupture of membranes in28(10%) and malpresentation in 22(7.88%) cases. Commonest fetal congenital anomaly wasanencephaly in 36(13%), hydrocephaly in 15(5.3%) and cleft lip and palate in 13(4.6%) cases.Out of 279 feti, 42(15%) were intrauterine deaths and 28(10%) were stillborns. Conclusion:Early diagnosis, timely referral, termination if needed and good management in labor toavoid complications are keys to deal with a polyhydramnios patient. Antenatal care should beemphasized amongst the women and families.
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MOISE, KENNETH J. "Polyhydramnios." Clinical Obstetrics and Gynecology 40, no. 2 (1997): 266–79. http://dx.doi.org/10.1097/00003081-199706000-00004.
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CARDWELL, MICHAEL S. "Polyhydramnios." Obstetrical & Gynecological Survey 42, no. 10 (1987): 612–17. http://dx.doi.org/10.1097/00006254-198710000-00001.
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Atalay, Ayşegül, Tuğba Gül Yılmaz, and Saliha Sağnıç. "Etiology and Perinatal Outcome of Polyhydramnios: An Experience of Tertiary Center." Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 22, no. 1 (2025): 26–30. https://doi.org/10.38136/jgon.1637070.
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Aim: To review our experience in fetuses with prenatally diagnosed with polyhydramniosis Materials and Method: Retrospective study of fetuses prenatally diagnosed with polyhydramniosis between October 2023 and January 2025 in a tertiary referral center. Results: 104 pregnant women were included in the final analysis. When we classify the cases according to etiology of polyhydramnios, 31 (29.8 %) women had pregestational or gestational diabetes, in 8 (7.6 %) infants major structural or significant genetic anomalies were detected prenatally or postnatally, 65 (62.6 %) cases were classified as idiopathic and recent TORCH positivity was not observed in any of the cases 0 (0%). Most cases were delivered at term (81.8%), median gestational week at delivery was 36 (range, 23-41), and the mean standard deviation birthweight was 2996±969 grams. Polyhydramnios was more common in male than in female fetuses (67% vs 33%). Termination of pregnancy was selected in 1 (0.9%) of the cases diagnosed with acrania and performed at 23 weeks of pregnancy with fetocide. There were 2 intrauterine fetal demise at 32 and 35 weeks of gestation diagnosed with Trisomy 18 and cardiac anomaly respectively. 101 (97.1 %) were live born and 29 of 101 live born infants were needed neonatal intensive care unit. Conclusion: Glucose tolerance test, detailed sonography, including fetal echocardiography should be performed in the pregnancies complicated with polyhydramnios. However, it is also reassuring for parents that the vast majority of cases are idiopathic.
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Hill, Lyndon. "Resolving Polyhydramnios." American Journal of Perinatology 5, no. 01 (1988): 61–63. http://dx.doi.org/10.1055/s-2007-999656.
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Denehy, T. R., D. I. Hollander, A. Dembner, and J. L. Breen. "Acute polyhydramnios." International Journal of Gynecology & Obstetrics 28, no. 2 (1989): 181–84. http://dx.doi.org/10.1016/0020-7292(89)90480-3.
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Moss, Heather, William L. Riley, Alicia Mastronardi, Leanne E. Brechtel, Mithil D. Patel, and Callie Reeder. "Prevalence of Large for Gestational Age and Polyhydramnios on Late Third-Trimester Ultrasound and Associated Adverse Pregnancy Outcomes [ID 2683531]." Obstetrics & Gynecology 143, no. 5S (2024): 35S—36S. http://dx.doi.org/10.1097/01.aog.0001013416.72971.24.
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INTRODUCTION: The objective of this study was to evaluate the prevalence of large for gestational age (LGA) and polyhydramnios found on ultrasound performed between 34 and 38 weeks of gestation and investigate the prevalence of gestational diabetes and delivery outcomes in this population. METHODS: A retrospective cross-sectional study (IRB #4869) was performed including chart review of late third-trimester ultrasounds performed on singleton pregnancies between 34 and 38 weeks of gestation from April 2020 to April 2022 at a hospital-owned private practice. Patients were grouped as no LGA (estimated fetal weight >90%) or polyhydramnios (amniotic fluid index ≥25 or maximum vertical pocket ≥8) or LGA and/or polyhydramnios. Differences in cesarean delivery (CD), gestational diabetes diagnosis, and macrosomia between groups were assessed via χ2 and Fisher's exact tests. RESULTS: Of 1,510 pregnancies, 15.0% (227/1,510) were diagnosed with LGA and/or polyhydramnios on late third-trimester ultrasound. The overall prevalence of CD in the group without LGA and/or polyhydramnios was 25.5%, whereas the rate of CD in patients having LGA and/or polyhydramnios was 44.1% (P<.001). The overall prevalence of macrosomia in the group without LGA and/or polyhydramnios was 8.8%, whereas the rate of macrosomia in patients having LGA and/or polyhydramnios was 17.2% (P<.001). The prevalence of diabetes in pregnancy was not significantly different between groups (without LGA and/or polyhydramnios 12.2% versus having LGA and/or polyhydramnios 16.7%; P=.081). CONCLUSION: Patients with LGA and/or polyhydramnios on late third-trimester ultrasound had significantly higher rates of CD and macrosomia. They were not more likely to have a diagnosis of diabetes during pregnancy. Late third-trimester ultrasound findings of LGA and/or polyhydramnios could be useful in detecting undiagnosed and/or missed diabetes. Future work will evaluate the timing of gestational diabetes screening and subsequent testing for diabetes if findings suggest LGA and/or polyhydramnios.
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Siveregi, Amon, Anne Horak, and Chantal Stewart. "Causes, management and outcomes of polyhydramnios at a secondary level hospital in Cape Town, South Africa." PLOS ONE 20, no. 3 (2025): e0317256. https://doi.org/10.1371/journal.pone.0317256.
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Introduction Polyhydramnios is associated with both maternal and fetal adverse outcomes. Idiopathic polyhydramnios, regardless of its severity category, was considered not to be associated with an increase in adverse outcomes. In contrast, when conditions such as congenital and chromosomal abnormalities or diabetes mellitus are detected, neonatal and maternal adverse outcomes can be up to five times higher. We thus aimed to document the outcomes of patients with mild, moderate and severe polyhydramnios according to whether an underlying cause was found and which management protocol was followed. Methodology We conducted a retrospective cohort study of all patients with polyhydramnios on ultrasound examination at our secondary hospital between January 1, 2018 and December 31, 2020. Hospital folders were reviewed. We recorded demographic data, information on underlying causes, management and outcomes. We summarised categorical variables using count (percentage). We tested the association between categorical variables using the chi-square test. Statistical significance was set at p < 0.05. Results A total of 136 patients with polyhydramnios (80 mild, 42 moderate, and 14 severe) were included. Most cases of polyhydramnios were idiopathic regardless of category [81.2% (65/80), 78% (32/42) and 78% (11/14) in the mild, moderate and severe groups, respectively]. The likelihood of occurrence of the composite adverse outcome, was higher with increasing severity of polyhydramnios, with 6.75%. 19.05%, and 35.71% in the mild, moderate and severe groups, respectively, having the composite adverse outcome (p = 0.01). Elective delivery before 40 weeks’ gestation for polyhydramnios in patients with idiopathic polyhydramnios was associated with a significant reduction in the occurrence of the composite adverse outcome compared to awaiting spontaneous labor (3.77% versus 15.79%, p = 0.036),. Conclusions Adverse outcomes were related to severity of the polyhydramnios and were significantly lower in the mild compared to the moderate and severe groups, with the rate of adverse outcome in the mild group comparable to that of the general population. Early delivery before 40 weeks gestation may be associated with benefit in moderate and severe groups of polyhydramnios.
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Pagan, M., E. F. Magann, N. Rabie, S. C. Steelman, Z. Hu, and S. Ounpraseuth. "Idiopathic Polyhydramnios and Pregnancy Outcome: Systematic Review and Meta-analysis." Obstetrical & Gynecological Survey 78, no. 9 (2023): 515–17. http://dx.doi.org/10.1097/01.ogx.0000979664.42491.de.
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ABSTRACT Amniotic fluid volume (AFV) is examined via ultrasound often several times in pregnancy and can be an indicator of the overall health of a fetus. However, disorders of amniotic fluid can arise without complications for the fetus; excess of amniotic fluid without any accompanying fetal conditions is referred to as idiopathic polyhydramnios. Previous research has shown conflicting results with regard to outcomes related to idiopathic polyhydramnios, with some finding it increases adverse outcomes and others reporting an increase in adverse outcomes only in moderate or severe cases. This study is a systematic review and meta-analysis meant to assess the relationship between idiopathic polyhydramnios and perinatal outcomes for singleton pregnancies. Eligibility criteria included studies that had a control group with normal AFV and defined polyhydramnios as an amniotic fluid index of 24 cm or greater or a single deepest pocket of 8 cm or greater. Similar methods of defining polyhydramnios were considered as long as they were evidence-based. Studies with known causes of polyhydramnios were excluded to ensure cases analyzed for this study were idiopathic. The primary outcome was intrauterine fetal demise, with secondary outcomes of neonatal death, neonatal intensive care unit (NICU) admission, macrosomia, 5-minute Apgar score, malpresentation, and cesarean delivery. Final review and analysis included 12 articles, with a total of 2392 patients with idiopathic polyhydramnios and 160,135 patients with normal AFV. Risk of bias was determined to be low for these studies, although the comparability was not well-defined. Analysis for the primary outcome included 8 of the 12 studies and showed that the risk of intrauterine fetal demise was increased in those with idiopathic polyhydramnios (odds ratio [OR], 7.64; 95% confidence interval [CI], 2.50–23.38). Secondary outcome analysis for neonatal death showed that individuals with polyhydramnios were 8.68 times more likely to experience neonatal death than controls (95% CI, 2.91–25.87). Examining other secondary outcomes, the association between NICU admission and idiopathic polyhydramnios showed that patients with polyhydramnios were more likely to be admitted to the NICU (OR, 1.94; 95% CI, 1.45–2.59). When assessing 5-minute Apgar scores, results showed that individuals with polyhydramnios were more likely to have an Apgar score of less than 7 (OR, 2.21; 95% CI, 1.34–3.62). In addition, rates of cesarean delivery were significantly higher with idiopathic polyhydramnios (OR, 2.31; 95% CI, 1.79–2.99), as was macrosomia (OR, 2.93; 95% CI, 2.39–3.59). Malpresentation was also higher in the polyhydramnios group than in the control group (OR, 2.73; 95% CI, 2.06–3.61). The authors of this meta-analysis conclude that in pregnancies with idiopathic polyhydramnios, there is an elevated risk of both intrauterine fetal demise and neonatal death. In addition, all other negative pregnancy outcomes analyzed were more common in pregnancies affected by idiopathic polyhydramnios. One limitation of this review is the heterogeneity inherent in analyzing many studies with different sample characteristics and different analysis methods. Although efforts were made to reduce bias, there is some inherent bias that cannot be accounted for completely. Further research is needed to fully characterize the clinical implications of the increased risk for adverse pregnancy outcomes shown here. This study also showed an increased risk based on the current clinical threshold for polyhydramnios, but more data are needed on accurate AFV thresholds and the clinical implications stemming from various thresholds.
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Lapaire, Olav, Wolfgang Holzgreve, Rosanna Zanetti-Daellenbach, Moffat Ecker Refecca, Hbsli Irene, and Tercanli Sevgi. "Polyhydramnios: An Update." Donald School Journal of Ultrasound in Obstetrics and Gynecology 1, no. 1 (2007): 73–79. http://dx.doi.org/10.5005/jp-journals-10009-1086.
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Abstract Maternal, fetal or placental pathologies may result in an excessive amount of amniotic fluid (AF) volume. Therefore, the surveillance of the AF volume, predominantly by ultrasound, has become an important instrument for the assessment of fetal well-being. An excessive accumulation of amniotic fluid, as a consequence of a disturbed balance between production, fetal resorption and secretion, is defined as polyhydramnios. Its degree correlates significantly with fetal morbidity and mortality. Therefore, polyhydramnios is an important clinical pattern in perinatal medicine. Approximately 20 percent of the fetuses with severe polyhydramnios show a congenital anomaly, whereas 50 percent of all cases are considered to be idiopathic, mostly with mild patterns. Furthermore, the likelihood of aneuploidy varies from 0.4 to 10 percent. Early detection, provides a correct diagnosis and allows a individual therapy. A referral to a tertiary center is advised in case of severe polyhydramnios and unknown etiology. In this review, current diagnostic as well as therapeutical aspects are discussed.
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Lalchan, Subita, Prakash Sharma, and Sangeeta Devi Gurung. "Prevalence of Congenital Anomalies in Polyhydramnios: A hospital based study from Western Nepal." Nepalese Journal of Radiology 8, no. 1 (2018): 25–29. http://dx.doi.org/10.3126/njr.v8i1.20452.
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Introduction: Polyhydramnios is excessive amount of amniotic fluid in relation to gestational age. It is frequently associated with congenital anomalies of the fetus. The aim of this study was to see the prevalence of congenital anomalies in polyhydramnios.Methods: Singleton pregnant irrespective of gestational age with amniotic fluid index more than 25 were included in the study. Degree of polyhydramnios was graded as mild, moderate and severe. Detail study of fetus was done for possible congenital anomalies. Congenital anomalies were confirmed with post-natal findings.Results: There were 39 pregnant women with amniotic fluid index (AFI) > 25 cm. Prevalence of polyhydramnios was 0.3%. Congenital anomalies were present in 31.6 % of pregnant women with polyhydramnios. In pregnant women with severe polyhydramnios; 66.6 % had congenital anomalies. Central nervous system, gastrointestinal and skeletal anomalies were the frequent anomalies associated with polyhydramnios.Conclusion: Polyhydramnios is associated with increased risk of congenital anomalies hence a detail survey of fetus should be done for possible congenital anomalies.
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Rajgire, Aditi Anil, Kiran Rajendra Borkar, and Amruta Madan Gadge. "A clinical study of fetomaternal outcome in pregnancy with polyhydramnios." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, no. 1 (2016): 145. http://dx.doi.org/10.18203/2320-1770.ijrcog20164648.
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Background: Amniotic fluid not only provides protection to the fetus from traumatic forces, cord compression, and microbial pathogens, but also plays an integral role in the normal development of the fetal musculoskeletal, pulmonary, and gastrointestinal systems. Polyhydramnios, defined as an excessive amount of amniotic fluid, complicates approximately 0.4-3.3% of all pregnancies. Fetal conditions that are associated with polyhydramnios include major congenital anomalies and both the immunologic and non-immunologic forms of hydrops foetalis. Maternal medical conditions are also known to be associated with polyhydramnios and subsequently alter perinatal outcome. So by diagnosing these cases as early as possible, these maternal complications can be prevented and advise proper prenatal counseling in relevant cases.Methods: This study was conducted in obstetrics and gynaecology department at a tertiary care hospital, over the period of from September 2015 to September 2016. Prospective observational study.Results: Polyhydramnios is commoner in primigravida. Causative factor are mainly idiopathic after which the most important is fetal defects. Diabetes is also associated finding with polyhydramnios in 8.3% cases. The occurrence of fetal congenital abnormality was directly proportional to the gestational age of pregnancy. Incidence of congenital abnormality was found to be 1.25 %. Congenital heart disease and cleft lip and cleft palate (3%) were the commonest congenital abnormality associated with polyhydramnios followed by anencephaly and spina bifida (3.3%).Conclusions: In our study Idiopathic polyhydramnios was found to be the most common cause of polyhydramnios. A careful study must be done for detection of etiological factors in all cases of polyhydramnios, careful screening, prenatal and antenatal counseling will help to improve the foetal outcome as well as to prevent the maternal complication.
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Jalal, Sadaf, Saima Khattak, and Alia Firdus. "Frequency of Polyhydramnios among Patients with Preterm Delivery at Lady Reading Hospital, Peshawar." Pakistan Journal of Medical and Health Sciences 16, no. 8 (2022): 63–65. http://dx.doi.org/10.53350/pjmhs2216863.
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Background: The elevated risk of premature delivery should be discussed with polyhydramnios patients. It is advisable to measure the cervical length to evaluate whether or not it is necessary to administer steroids to encourage foetal lung maturity. Patients should also be made aware of the dangers associated with unstable labour necessitating caesarean delivery, umbilical cord prolapse, abruptio placentae, and postpartum haemorrhage. Aim: To determine the frequency of polyhydramnios among patients with preterm delivery presenting to Lady Reading Hospital Peshawar. Study design: Cross-sectional study. Place and duration of study: Department of Obstetrics & Gynaecology, Lady Reading Hospital Peshawar from 1st November 2019 to 25th April 2020. Methodology: One hundred and eighty one women with preterm delivery, gestation age of 24-36 weeks and age between 18-45 years were included. The obstetrical records of these patients were evaluated for the presence of polyhydramnios using AFI they were classified as mild, moderate, and severe polyhydramnios based on AFI. Results: The mean age was 30.39±3.53 years, mean weight of 68.33±7.52 Kg and mean height of 1.59±.0.07 meters, mean BMI 27.07±3.71 kg/m2, mean gestational age 32.30±1.89 weeks and mean AFI was 18.38±6.85 cm. Polyhydramnios was seen in 17.7% of patients. Mild polyhydramnios was 28.1%, moderate 40.6%, and severe was 31.3%. Conclusion: Preterm labour appeared to be influenced more by the underlying aetiology of polyhydramnios than by the relative excess of amniotic fluid as identified by this investigation Keywords: Preterm delivery, Polyhydramnios, Severity
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Mithra, Prasanna, Nikitha Mathews, Aminath Afaa, Mariyam Hudha, Aishath Thasneem, and Anjali Das. "IJCM_99A: Risk Factors Associated with Polyhydramnios among Pregnant Women in Mangalore: A Case Control Study." Indian Journal of Community Medicine 49, Suppl 1 (2024): S29. http://dx.doi.org/10.4103/ijcm.ijcm_abstract99.
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Background: The amniotic fluid volume is maintained by a balance between production (fetal urine and fetal lung fluid) and resorption (swallowing and intramembranous flow). Any imbalance in this process could lead to either oligohydramnios or polyhydramnios. The incidence of polyhydramnios varies from 1-2%. It is a significant obstetric condition, the etiology of which is still largely unknown. The underlying maternal factors include diabetes mellitus, pregnancy induced hypertension, twin pregnancy, negative Rh factor, cardiac and renal diseases. The study aims to study the risk factors associated with polyhydramnios among the women seeking maternal health care in the study hospitals and to assess the socio-demographic correlates of polyhydramnios among the study population. Methodology: The study was conducted in the Government Lady Goschen Hospital and Kasturba Medical College Attavar, among 66 cases (Pregnant women admitted with polyhydramnios) and 132 controls(age matched pregnant women admitted to the study hospitals during the study period). Odds ratio was calculated, Chi square test was used to compare the groups. Results: Proportion of anemia among our cases was 20% and control was 25.6%. 7.6% of the cases were associated with hypertensive disorders of pregnancy and 0.8% of controls had hypertensive disorders. 12.1% of polyhydramnios cases with Gestational Diabetes Mellitus Conclusion: Majority of the polyhydramnios cases were in the age group 20-29 years. The proportion of Diabetes Mellitus, hypertension, Rh negative pregnancies, malpresentation were higher among polyhydramnios cases. The association was significant for hypertension.
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Apurva, Khatokar. "Polyhydramnios-Maternal and Foetal Outcomes in Pregnancy." International Journal of Medical and Pharmaceutical Research 4, no. 2 (2023): 579–87. https://doi.org/10.5281/zenodo.7898848.
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<strong>Introduction</strong>: Excessive accumulation of liquor amnii causing discomfort to the patient and/or when an imaging help is needed to substantiate the clinical diagnosis of the lie and presentation of the foetus is referred to as polyhydramnios[1]. It develops as a consequence of disturbed equilibrium between production, foetal resorption, and secretion of amniotic fluid[2]. Polyhydramnios is associated with maternal Diabetes Mellitus, increased rate of Caesarean sections due to malpresentations, postpartum haemorrhage, congenital anomalies in new-born, preterm deliveries, increased risk of NICU admissions and still births[3]. Hence our study is prompted to find out maternal and perinatal outcomes in women with polyhydramnios in pregnancy and to improve the maternal and perinatal outcome in polyhydramnios cases. <strong>Aims and Objectives</strong>: To study the risk factors associated with polyhydramnios affecting polyhydramnios in pregnancies >28wks of gestational age, its clinical presentation, mode of delivery and feto-maternal outcomes in polyhydramnios in a tertiary care centre. <strong>Methods</strong>: It was a prospective observational study conducted for 2 years from November 2020 to October 2022 at tertiary care centre. The data retrieved from the medical records on polyhydramnios included demographic data, complications of pregnancy, and maternal and neonatal outcomes. Appropriate Statistical analysis was performed. <strong>Results</strong>: 100 cases of polyhydramnios cases were studied. Majority cases were idiopathic (57%) and had mild polyhydramnios (54%) with AFI of 25-27cm. Most significant risk factor was congenital anomalies (19%). Most common maternal complication was preterm delivery (24%). Other maternal complications were premature rupture of membranes (16%), malpresentations (12%), cord prolapse (4%), cord presentation (4%) and post-partum haemorrhage (2%). 58% cases were delivered by Caesarean section. 19% neonates had various congenital anomalies and 4% babies with major congenital anomalies died. 12% babies were still born due to various causes such as major congenital anomalies in 4 cases, birth asphyxia in 4 cases, abruptio placentae in 2 mothers and cord prolapse intrapartum in 2 cases. Neonatal death rate was 35.29. <strong>Conclusion</strong>: Polyhydramnios has high maternal and neonatal complications, especially congenital anomalies and preterm delivery that increases risk of significant neonatal complications and a higher rate of Caesarean sections.
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Saido, Vaman Abdulazeez, and Jinan Nori Hasan. "The Effect of Amniotic Fluid Changes in Late Pregnancy on Maternal And Fetus Outcomes." Journal of duhok university 25, no. 2 (2022): 210–21. http://dx.doi.org/10.26682/sjuod.2022.25.2.20.
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The amniotic sac contains a protective liquid known as amniotic fluid. Two different types of amniotic fluid changes have been identified. The first is oligohydramnios, and the second is polyhydramnios. This study aimed to examine the effect of amniotic fluid changes on pregnancy outcomes and the fetus. A cross-sectional study was conducted by simple random sampling for, Four hundred fifty women from November 1st, 2021, until February28th 2022, in Duhok hospital for Obstetrics and Gynecology. The study revealed that the greatest rates of polyhydramnios were associated with gestational hypertension (22.7%) and gestational diabetes (19.3%). The most prevalent mode of delivery in all groups was cesarean section. Hypoglycemia had the greats incidence in polyhydramnios at (11.3%). There was a statistically significant association between amniotic fluid volume and baby gender, with males being more prevalent in oligohydramnios (58.7%) and polyhydramnios (57.3%) compared to normal amniotic fluid volume. Moreover, polyhydramnios had more effects on maternal and baby poor outcomes than oligohydramnios. Thyroid disease, diabetes mellitus, and hypertension were the most common types of chronic illnesses in polyhydramnios group compared with oligohydramnios group and normal amniotic fluid group. Apgar score, birth weight, congenital anomalies, hypoglycemia, asphyxia, and respiratory distress syndrome were statistically significant with oligohydramnios, polyhydramnios and normal amniotic fluid volum
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Lerner, Yael, Tzuria Peled, Morag Yehushua, et al. "Labor Induction in Women with Isolated Polyhydramnios at Term: A Multicenter Retrospective Cohort Analysis." Journal of Clinical Medicine 13, no. 5 (2024): 1416. http://dx.doi.org/10.3390/jcm13051416.
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Background: With the increasing popularity of elective induction after 39 + 0 weeks, the question of whether induction of labor (IOL) is safe in women with isolated polyhydramnios has become more relevant. We aimed to evaluate the pregnancy outcomes associated with IOL among women with and without isolated polyhydramnios. Methods: This was a multicenter retrospective cohort that included women who underwent induction of labor at term. The study compared women who underwent IOL due to isolated polyhydramnios to low-risk women who underwent elective IOL due to gestational age only. The main outcome measure was a composite adverse maternal outcome, while the secondary outcomes included maternal and neonatal adverse pregnancy outcomes. Results: During the study period, 1004 women underwent IOL at term and met inclusion and exclusion criteria; 162 had isolated polyhydramnios, and 842 had a normal amount of amniotic fluid. Women who had isolated polyhydramnios had higher rates of the composite adverse maternal outcome (28.7% vs. 20.4%, p = 0.02), prolonged hospital stay, perineal tear grade 3/4, postpartum hemorrhage, and neonatal hypoglycemia. Multivariate analyses revealed that among women with IOL, polyhydramnios was significantly associated with adverse composite maternal outcome [aOR 1.98 (1.27–3.10), p < 0.01]. Conclusions: IOL in women with isolated polyhydramnios at term was associated with worse perinatal outcomes compared to low-risk women who underwent elective IOL. Our findings suggest that the management of women with polyhydramnios cannot be extrapolated from studies of low-risk populations and that clinical decision-making should take into account the individual patient’s risk factors and preferences.
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Pasquini, Lucia, Ilaria Ponziani, Marta Pallottini, et al. "Obstetric and Neonatal Outcomes in Mild Idiopathic Polyhydramnios." Children 9, no. 11 (2022): 1624. http://dx.doi.org/10.3390/children9111624.
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Background: Idiopathic polyhydramnios is a controversial clinical condition, as data on perinatal outcomes are conflicting and vary depending on the severity of the condition. The aim of the present study was to compare obstetric and neonatal outcomes between pregnant women with mild idiopathic polyhydramnios and a control population. Methods: A retrospective cohort study was performed at a single university hospital comparing the obstetrics and neonatal outcomes of pregnancies with mild idiopathic polyhydramnios (n = 109) and control pregnancies (n = 2550). Results: Cesarean section (CS) was significantly increased in the group with polyhydramnios compared to controls (46% vs. 32%, respectively, p = 0.047) due to a higher rate of emergency CS in the polyhydramnios group (p = 0.041) because of abnormal cardiotocography (7.3% vs. 2.9%; p = 0.018) or labor dystocia (8.2% vs. 2.9%; p = 0.006). No statistically significant difference was found in the Apgar score, in the rate of neonatal hypoxia, or in the incidence of macrosomia between groups. In four cases, additional diagnoses of anomalies were made after birth, with a rate of 3.2%, which is comparable to the general population. Conclusion: Besides an increased risk of CS, patients with mild idiopathic polyhydramnios should be reassured regarding maternal and feto-neonatal outcomes. The management of pregnancies with stable mild idiopathic polyhydramnios should not differ from uncomplicated pregnancies, except for the need for increased labor surveillance.
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Tasneem Azhar, Iram Aslam, Nadia Sharif, Uzma Manzoor, Saadia Bano, and Uzair Iqbal. "Polyhydramnios: Heterogeneity in presentation at tertiary care hospital." Professional Medical Journal 32, no. 04 (2025): 455–58. https://doi.org/10.29309/tpmj/2025.32.04.8332.
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Objective: To determine the presentation and outcome of polyhydramnios in pregnancy at a tertiary care hospital. Study Design: Descriptive Cross-sectional study. Setting: Department of Obstetrics and Gynaecology, Independent University Hospital Faisalabad. Period: 1-Jan-2020 to 31-Dec-2022. Methods: All the cases diagnosed as polyhydramnios after confirmation on ultrasonography by measuring single deepest vertical pool were included. Results: The total number of patients included in the study were 80. The patients having age <35 years were 62 (77.5%) while the patients having age > 35 years were 18 (22.5%). 16 patients (20%) were primigravida while 64 patients (80%) were multigravida. The patients with Mild polyhydramnios were52 (65%), moderate polyhydramnios 21 (26.5%) and with severe polyhydramnios 7 (8.7%). The various maternal complications were as preterm labour in 11 patients (13.7%), gestational diabetes mellitus 8 patients (10%), Pre-PROM 7 patients (8.75%), PIH and its complications 3 patient (3.75%) and Placental abruption 2 patients (2.5%). while 49 patients (61.25%) had no complications. Regarding mode of delivery 13 patients (16.3%) were delivered vaginally while 67 patients (83.7%) underwent caesarean section. Fetal outcome was quite good. There were normal alive babies 67 (83.75%), anomalous 9 (11.25%) and 4 babies (5%) were diagnosed as IUD. Conclusion: In the present study, polyhydramnios had diversity in its presentation and maternal versus fetal outcome was associated with degree of polyhydramnios.
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Salloum, Daria, Paweł Jan Stanirowski, Aleksandra Symonides, Paweł Krajewski, Dorota Bomba-Opoń, and Mirosław Wielgoś. "Enlarged Abdominal Lymph Node as a Cause of Polyhydramnios in the Course of Congenital Neonatal Leukaemia: A Case Report and Review of the Literature on Foetal Abdominal Tumours with Coexisting Polyhydramnios." Journal of Clinical Medicine 11, no. 21 (2022): 6598. http://dx.doi.org/10.3390/jcm11216598.
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Polyhydramnios represents a complication found in 0.2–2% of pregnancies, and it is usually diagnosed between 31 and 36 weeks of pregnancy. Although most cases of polyhydramnios are idiopathic, maternal diabetes or foetal malformations constitute frequent causes of the excessive accumulation of the amniotic fluid. Considering the latter, polyhydramnios may rarely be caused by foetal abdominal tumours, with the incidence rate of 2–14 cases per 100,000 live births. Congenital neonatal leukaemia (CNL) is a rare disease with a reported incidence rate of 5–8.6 cases per million live births. In the prenatal period, the ultrasound abnormalities associated with CNL include hepatomegaly and splenomegaly. In this paper, we presented a case of polyhydramnios caused by mechanical pressure on the foetal gastrointestinal tract by an enlarged lymph node in the course of CNL, as well as reviewing the available literature on foetal abdominal tumours with concurrent polyhydramnios.
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Inde, Yusuke, Hidehiko Miyake, Akane Takaya, Shuichi Ono, Miwa Igarashi, and Shunji Suzuki. "A Case of Monochorionic-Diamniotic Twin Pregnancy with Polyhydramnios-Polyhydramnios Sequence." Journal of Nippon Medical School 76, no. 2 (2009): 93–95. http://dx.doi.org/10.1272/jnms.76.93.
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Bas Lando, Maayan, Marnina Urman, Yifat Weiss, et al. "Term Idiopathic Polyhydramnios, and Labor Complications." Journal of Clinical Medicine 12, no. 3 (2023): 981. http://dx.doi.org/10.3390/jcm12030981.
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Background and Aim: Polyhydramnios is associated with an increased risk of various adverse pregnancy outcomes, yet complications during labor have not been sufficiently studied. We assessed the labor and perinatal outcomes of idiopathic polyhydramnios during term labor. Methods: Retrospective cohort study at a tertiary medical center between 2010 and 2014. Women with idiopathic polyhydramnios defined as an amniotic fluid index (AFI) greater than 24 cm or a deep vertical pocket (DVP) > 8 cm (cases) were compared with women with a normal AFI (5–24 cm) (controls). Statistics: Descriptive, means ± SDs, medians + IQR. Comparisons: chi-square, Fisher’s exact test, Mann–Whitney Test, multivariate logistic models. Results: During the study period 11,065 women had ultrasound evaluation completed by a sonographer within two weeks of delivery. After excluding pregnancies complicated by diabetes (pre-gestational or gestational), fetal anomalies, IUFD, multifetal pregnancies, elective cesarean deliveries (CD) or missing data, we included 750 cases and 7000 controls. The degree of polyhydramnios was mild in 559 (75.0%) cases (AFI 24–30 cm or DVP 8–12 cm), moderate in 137 (18.0%) cases (30–35 cm or DVP 12–15 cm) and severe in 54 (7.0%) cases (AFI >35 cm or DVP > 15 cm). Idiopathic polyhydramnios was associated with a higher rate of CD 9.3% vs. 6.2%, p = 0.004; a higher rate of macrosomia 22.8% vs. 7.0%, p < 0.0001; and a higher rate of neonatal respiratory complications 2.0% vs. 0.8%, p = 0.0001. A multivariate regression analysis demonstrated an independent relation between polyhydramnios and higher rates of CD, aOR 1.62 (CI 1.20–2.19 p = 0.002) and composite adverse neonatal outcome aOR 1.28 (CI 1.01–1.63 p = 0.043). Severity of polyhydramnios was significantly associated with higher rates of macrosomia and CD (p for trend <0.01 in both). Conclusions: The term idiopathic polyhydramnios is independently associated with macrosomia, CD and neonatal complications. The severity of polyhydramnios is also associated with macrosomia and CD.
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Mohsin, Iram, Sadaf Aziz, Iram Aziz, Sehrish Azam, and Pareesae Hamayun. "Accuracy of Polyhydramnios for Detection of Fetal Anomalies on Ultrasound." Pakistan Armed Forces Medical Journal 73, no. 3 (2023): 776–79. http://dx.doi.org/10.51253/pafmj.v73i3.8528.
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Objective: To determine the diagnostic accuracy of polyhydramnios for detecting fetal anomalies on ultrasound in singleton pregnancies.
 Study Design: Cross-sectional study.
 Place and Duration of Study: Armed Forces Institute of Radiology and Imaging, Military Hospital, Rawalpindi Pakistan, from Oct 2018 to Apr 2019.
 Methodology: A total of 145 pregnant females coming for antenatal/anomaly scans, aged 18 to 45 years, were included. All scans were obtained with a 3.5-5 MHz curvilinear transducer and obstetric settings of the ultrasound machine. AFI was calculated as the sum of the deepest, unobstructed, vertical length of each pocket of fluid measured in cm in all four quadrants and then added to the others. The radiologist observed fetal structural anomalies.
 Results: Polyhydramnios was present in 15(10.34%) patients. The congenital fetal anomaly on ultrasound was present in 6(4.14%) cases. In polyhydramnios-positive patients, 05(3.4%) had a congenital fetal anomaly, and 10(6.8%) had no congenital fetal anomaly. Among 130 polyhydramnios-negative patients, 01(0.7%) had a congenital fetal anomaly, whereas 129(88.9%) had no congenital fetal anomaly. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of polyhydramnios for detecting fetal anomalies on ultrasound were 83.33%, 91.41%, 29.4%, 99.23% and 92.41%, respectively.
 Conclusion: This study concluded that the diagnostic accuracy of polyhydramnios¸, significantly moderate to severe forms, is relatively high for detecting fetal anomalies on ultrasound.Keywords: Fetal anomalies, Polyhydramnios, Ultrasonography.
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Kattaxodjaeva, Maxmuda Xamdamovna, Lola Sayfullaevna Abdullaeva, and Nodira Jumaevna Suleymanova. "THE VALUE OF PREDICTING POSTPARTUM HEMORRHAGE IN THE SYNDROME OF UTERINE OVERSTRETCHING IN THE PERSONIFICATION OF PREVENTIVE MEASURES." Journal of reproductive health and uro-nephrology research 3, no. 2 (2022): 4. https://doi.org/10.5281/zenodo.6678074.
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The problem of the development of polyhydramnios is relevant in connection with the complications of pregnancy and childbirth, both for the mother and for the fetus. One of the most dangerous complications is hypotonic bleeding in the postpartum period, which leads to an increase in maternal morbidity and mortality. Among the causes of bleeding, polyhydramnios, the frequency of which reaches 1–8% of the total pool of pregnant women, occupies one of the leading positions. The aim of the study was to study the features of the clinic and the morphological structure of the uterine wall in polyhydramnios of varying severity. All this dictates the need to improve ways to prevent hypotonic postpartum bleeding in women with polyhydramnios.<strong> </strong>
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Parmar, Manisha M., and Sandeep M. Parmar. "Study of amniotic fluid index and its pregnancy outcome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 12 (2019): 4727. http://dx.doi.org/10.18203/2320-1770.ijrcog20195309.
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Background: Amniotic fluid is vital to the well-being of the fetus. Severe oligohydramnios and polyhydramnios are associated with increased maternal morbidity and perinatal morbidity and mortality.Methods: This was prospective observational study conducted at tertiary teaching institute from July 2012 to July 2013. Total 200 patients were included in the study. On the basis of amniotic fluid index (AFI), patients were categorized in 3 groups, Normal AFI (8-24 cm), oligohydramnios (AFI <5cm) and polyhydramnios (AFI > = 25 cm). Results were analysed in the form of incidence, mode of delivery and perinatal outcome which includes preterm, low birth weight, still births, NICU admissions and neonatal deaths in all the 3 groups.Results: Out of 200 patients, there was 150 cases of normal AFI, 39 cases of oligohydramnios and 11 cases of polyhydramnios. Incidence of oligohydramnios was 4.1% and polyhydramnios was 1.1%. PIH was the most common etiological factor found in oligohydramnios (30.7%) and in polyhydramnios congenital anomalies (36.3%) followed by idiopathic cause (27.2%) was most common. Incidence of caesarean section was 58.9% in oligohydarmnios and 17.3% in normal AFI group. Incidence of NICU admission was 25.6% in oligohydramnios and 50% in polyhydramnios group in comparison to 9.3% in normal AFI group.Conclusions: Amniotic fluid index is an important part of antepartum fetal surveillance. Abnormalities of AFI are associated with high perinatal morbidity and mortality and maternal morbidity.
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Crimmins, Sarah, Cecilia Mo, Yomna Nassar, Jerome Kopelman, and Ozhan Turan. "Polyhydramnios or Excessive Fetal Growth Are Markers for Abnormal Perinatal Outcome in Euglycemic Pregnancies." American Journal of Perinatology 35, no. 02 (2017): 140–45. http://dx.doi.org/10.1055/s-0037-1606186.
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Objective This study aims to investigate the perinatal outcome of fetuses with polyhydramnios and/or accelerated growth among women with a normal oral glucose challenge test (oGCT). Methods Singleton, nonanomalous pregnancies with an oGCT(< 130 mg/dL) at 24 to 28 weeks, who subsequently demonstrate polyhydramnios (amniotic fluid index > 24 cm or maximum vertical pocket > 8 cm) and/or accelerated growth (abdominal circumference > 95th percentile) on two-third trimester examinations were studied. Maternal demographics, delivery, and neonatal information were recorded. Cases were compared with a reference group (normal oGCT with neither abnormal third-trimester growth nor polyhydramnios). Results A total of 282 pregnancies were in the study group, and 663 were in the reference group. Deliveries in the study group were at a higher risk for birth weight (BW)% > 90%, standard deviation, and postpartum hemorrhage when compared with the reference group (adjusted odds ratio: 2.3–5.6). Pregnancies complicated by both polyhydramnios and accelerated fetal growth were significantly more likely to result in a BW% > 90% (odds ratio [OR]: 18.5; 95% confidence interval [CI]: 8.9–38.6) and PPH (OR: 4.2; 95% CI: 2.4–7.6). Conclusion Pregnancies with normal oGCT that develop polyhydramnios and accelerated growth are at higher risk for maternal and neonatal complications. Isolated polyhydramnios without accelerated growth increases the risk for delivery complications but not neonatal morbidity.
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Gaistruk, N. A., L. G. Dubas, A. N. Gaistruk, A. V. Melnik, and O. L. Liovkina. "Pathogenetic role of vitamin D deficiency and immune-inflammatory disorders in development of fetal distress in pregnant women with chronic hydramnion." Likarska sprava, no. 3-4 (June 30, 2020): 14–20. http://dx.doi.org/10.31640/jvd.3-4.2020(3).
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The role of vitamin D deficiency and immune-inflammatory disorders in the mechanisms of development of fetal distress in pregnant women with chronic polyhydramnios remains unexplored. Objective: to evaluate the role of vitamin D deficiency and associated immune inflammatory disorders in the development of fetal distress in pregnant women with chronic polyhydramnios. Materials and methods. Surveyed 30 women with a physiological course of pregnancy and 90 pregnant women with chronic polyhydramnios. In the serum, the level of the metabolite of vitamin D – 25(OH)D and the cytokines IL-10 and IL-6 were determined by enzyme immunoassay using standard kits. Statistical processing of the obtained results was performed using standard methods using the «MS Excel» and «Statistica SPSS 10.0 for Windows» application package. The results of the research. In pregnant women with chronic polyhydramnios, there is a significant decrease of the metabolite of vitamin D – 25(OH)D level by 21 % in the serum, a decrease of the level of the anti-inflammatory cytokine IL-10 by 26.4 % and an increase of the concentration of pro-inflammatory IL-6 by 17 % compared to women with physiological course of pregnancy. The occurrence of fetal distress against the background of chronic polyhydramnios is accompanied by a intensification of vitamin D deficiency and immune-inflammatory disorders: levels 25(OH)D and IL-10, respectively, by 18.5 % and 17.5 % less, and IL-6 by 13.3 %, than in women with chronic polyhydramnios without fetal distress. The expressiveness of immune disorders in the organism of pregnant women with chronic polyhydramnios is determined by the level of vitamin D in the organism. Thus, in women with a deficiency of 25(OH)D in the serum, a significant decrease in the IL-10 concentration by 47.8 % and a significant increase in the IL-6 level by 34.6 % were recorded in comparison with the indicators in women with vitamin D deficiency. Conclusions. Vitamin D deficiency and associated immune-inflammatory disorders play an important role in the development of fetal distress in pregnant women with chronic polyhydramnios.
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Majid, Faiza, Syeda Khadija, Shehzadi Irum, and Syed Muhammad Yousaf. "Sonographic Association of Polyhydramnios with Adverse Perinatal Outcomes in Diabetic Mothers from 34 to 40 Weeks of Pregnancy." European Journal of Health Sciences 7, no. 6 (2022): 25–33. http://dx.doi.org/10.47672/ejhs.1283.
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Objective: Polyhydramnios carries a high rate of complications during pregnancies and adverse perinatal outcomes. Obstetrical ultrasound screening is the prime tool to rule out any possible adverse outcome that might lead towards worst scenarios outcome such as growth retardation, C-section and preterm delivery. The objective of this study was to determine sonographic association of polyhydramnios with adverse perinatal outcomes in diabetic mothers from 34 to 40 weeks of pregnancy.
 Methodology: A cross sectional analytical study was carried out at the Department of Radiology in Services Hospital Lahore, Pakistan. Duration of study was from March 2017 to November 2017. Patients in 3rd trimester of pregnancy with Polyhydramnios and diabetes were chosen subsequent to fulfilling consideration (inclusion) and rejection (exclusion) criteria. A complete history and investigation were finished. All necessary examination done. Polyhydramnios confirmed by estimating amniotic fluid index. Statistical Software for Social Sciences (SPSS version 24) was used for analysis of all data. Standard and Mean Deviation (SD) remained calculated for continuous variables.
 Findings: The sample size was 101 in this study. While throughout the study period data of 89 patients was collected. Patients were between the age group of 18 to 35 years. Severity of polyhydramnios was classified as mild moderate and severe. Out of 89 babies delivered during study 66 had no complications while 4 were macrosomic, 1 infant suffered from shoulder dystocia, 1 was lager for gestational age, 3 had respiratory distress syndrome and 3 were smaller for gestational age. Hb1AC levels were higher in diabetic patients with the mean value of 6.18%. In this study, we found that polyhydramnios is associated with poor diabetic control. This research shows that polyhydramnios is associated with an increased risk of adverse perinatal outcomes, and there is a significant positive relation with maternal age, diabetes, fetal anomalies, and fetal macrosomia. Pregnant women with GDM showed higher risk of macrosomic newborns. This study demonstrates that the likelihood of an adverse perinatal outcome increases in association with polyhydramnios.
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Yartseva, M. A. "Pregnancy gestosis and polyhydramnios." Kazan medical journal 69, no. 5 (1988): 391–92. http://dx.doi.org/10.17816/kazmj99575.
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In the available literature, we did not find any works that would reveal the peculiarities of the course of gestosis in pregnant women with polyhydramnios. In addition, it would be interesting to study the incidence of gestosis and its development, taking into account the possible causes of amniotic fluid, to assess the outcome of pregnancy for the mother and fetus when these complications are combined. A total of 161 pregnant women with abundant amniotic fluid were followed up, and 142 of them (88.2%) had gestosis. Pregnant women aged 20 to 30 years comprised the main population (61.3%).
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Panting-Kemp, Andrea, Tuan Nguyen, and Lony Castro. "Substance abuse and polyhydramnios." American Journal of Obstetrics and Gynecology 187, no. 3 (2002): 602–5. http://dx.doi.org/10.1067/mob.2002.124292.
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Moore, Lisa. "263: Diabetes and polyhydramnios." American Journal of Obstetrics and Gynecology 204, no. 1 (2011): S112. http://dx.doi.org/10.1016/j.ajog.2010.10.281.
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Persutte, Wayne H. "Ultrasonographic Identification of Polyhydramnios." Journal of Diagnostic Medical Sonography 8, no. 2 (1992): 79–85. http://dx.doi.org/10.1177/875647939200800205.
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Anderson, Debra F., and J. Job Faber. "Animal model for polyhydramnios." American Journal of Obstetrics and Gynecology 160, no. 2 (1989): 389–90. http://dx.doi.org/10.1016/0002-9378(89)90454-7.
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Islamovna, Zakirova Fotima, Abdullaeva Nigora Erkinovna, and Telmanova Jasmina Farruxovna. "THE CONSEQUENCES OF POLYHYDRAMNIOS FOR THE MOTHER AND FETUS." International Journal of Medical Sciences And Clinical Research 03, no. 04 (2023): 125–28. http://dx.doi.org/10.37547/ijmscr/volume03issue04-20.
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Polyhydramnios is an obstetric pathology, which is characterized by an increase in the volume of amniotic fluid (amniotic fluid) of more than 1500 ml. The purpose of the study was to study the frequency of causes, the course of pregnancy, the outcome of childbirth and the condition of the newborn with polyhydramnios. To achieve this goal, a retrospective analysis of the history of childbirth of 72 women with polyhydramnios who delivered in the obstetric department of the Samara State Medical University clinic in 2022 was carried out. The course of pregnancy in women with polyhydramnios is complicated by: preeclampsia of the first and second half of pregnancy, miscarriage and premature birth. Perinatal outcomes are characterized by: intrauterine retention syndrome, prematurity, malformations of the central nervous system, cerebrovascular accidents and intrauterine infections.
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A Wahab, Syamimi Nadiah, Abdul Hadi Said, and Wan Hasmawati Wan Ismail. "Unravelling the unseen threat of polyhydramnios in patients with gestational diabetes mellitus: A case report." Malaysian Family Physician 18 (December 21, 2023): 70. http://dx.doi.org/10.51866/cr.377.
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Polyhydramnios is defined as an increase in the amount of amniotic fluid during pregnancy. This article presents the case of a 35-year-old G4P3 lady at 28 weeks of gestation with suboptimised gestational diabetes Mellitus (GDM). Routine transabdominal ultrasound showed the presence of polyhydramnios, initially thought to be due to suboptimal glucose control. Further evaluation revealed a congenital diaphragmatic hernia with multiple soft markers. Identifying the underlying causes of polyhydramnios can be challenging in primary care settings, which can be attributed to various factors. Although primary care medical officers may not be required to perform detailed scans, they have a crucial role in identifying gross foetal abnormalities. This study highlights the potential for missed diagnoses in primary care settings and the importance of comprehensive prenatal assessments to ensure early detection and appropriate management of polyhydramnios-related conditions in women with GDM.
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Navakauskienė, Rūta, Sandra Baronaitė, Dalius Matuzevičius, et al. "Comparative Proteomic Assessment of Normal vs. Polyhydramnios Amniotic Fluid Based on Computational Analysis." Biomedicines 10, no. 8 (2022): 1821. http://dx.doi.org/10.3390/biomedicines10081821.
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Mass spectrometry-based proteomics have become a valued tool for conducting comprehensive analyses in amniotic fluid samples with pathologies. Our research interest is the finding and characterization of proteins related to normal vs. polyhydramnios (non-immune hydrops) pregnancy. Proteomic analysis was performed on proteins isolated from fresh amniotic fluid samples. Proteins were fractionated by 2DE using a different pI range (pI 3–11, pI 4–7) and analyzed with MALDI-TOF-MS. Furthermore, by using computational analysis, identified proteins in protein maps specific to normal vs. polyhydramnios pregnancy were compared and the quantities of expressed proteins were evaluated mathematically. Comparative analysis of proteome characteristic for the same polyhydramnios pregnancy fractionated by 2DE in different pI range (3–11 and 4–7) was performed and particular protein groups were evaluated for the quantification of changes within the same protein level. Proteins of normal and polyhydramnios pregnancies were fractionated by 2DE in pI range 3–11 and in pI range 4–7. Mass spectrometry analysis of proteins has revealed that the quantity changes of the main identified proteins in normal vs. polyhydramnios pregnancy could be assigned to immune response and inflammation proteins, cellular signaling and regulation proteins, metabolic proteins, etc. Specifically, we have identified and characterized proteins associated with heart function and circulatory system and proteins associated with abnormalities in prenatal medicine. The following are: serotransferrin, prothrombin, haptoglobin, transthyretin, alpha-1-antitrypsin, zinc-alpha-2-glycprotein, haptoglobin kininogen-1, hemopexin, clusterin, lumican, afamin, gelsolin. By using computational analysis, we demonstrated that some of these proteins increased a few times in pathological pregnancy. Computer assistance analysis of 2DE images suggested that, for the better isolation of the proteins’ isoforms, those levels increased/decreased in normal vs. polyhydramnios pregnancy, and the fractionation of proteins in pI rage 3–11 and 4–7 could be substantial. We analyzed and identified by MS proteins specific for normal and polyhydramnios pregnancies. Identified protein levels increased and/or modification changed in case of non-immune hydrops fetus and in cases of cardiovascular, anemia, growth restriction, and metabolic disorders. Computational analysis for proteomic characterization empower to estimate the quantitative changes of proteins specific for normal vs. polyhydramnios pregnancies.
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M., Vidyasagara, Chandrashekhar T., and Sunil S. Raikar. "Correlation of amniotic fluid index with fetomaternal outcome." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, no. 8 (2021): 3137. http://dx.doi.org/10.18203/2320-1770.ijrcog20212969.
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Background: Amniotic fluid acts like a protective cover around the baby. Advances in ultrasound have increased early detection of abnormal amniotic fluid volumes. Any variation in the amniotic fluid volume warrants antenatal foetal surveillance.Methods: 300 pregnant women between 37 to 40 weeks of gestation were included in the study. A detailed history, examination and ultrasound was done. Pregnant women were divided into 3 groups’ i.e. normal liquor, oligohydramios and polyhydramnios. All the women were closely monitored during labour and puerperium. Follow-up was done till 7 days post-delivery. Maternal and neonatal data were collected.Results: 300 pregnant women were included in the study, out of which 221 had normal amniotic fluid index (AFI), 64 had oligohydramnios and 15 had polyhydramnios. All baseline characteristics were comparable between the groups except body mass index (BMI). Incidence of meconium stained liquor was significantly higher in oligohydramnios compared to normal AFI and polyhydramnios groups (34.4% versus 10.5% versus 13.3%; p=0.0001). Caesarean section rates were significantly higher in polyhydramnios and oligohydramnios compared to normal AFI group (73.3% versus 70.3% versus 19.9%; p=0.0001). Higher cases of low birth weight were recorded in oligohydramnios group compared to normal AFI and polyhydramnios group group (32.8% versus 18.6% versus 13.3%; p=0.011). Neonatal intensive care unit (NICU) admissions were higher in oligohydramnios (35.9%) and polyhydramnios (33.3%) compared to normal AFI group (35.9% versus 33.3% versus 12.7%; p=0.0001).Conclusions: Abnormal liquor volumes are associated with increased caesarean section rates, NICU admissions and neonatal mortality. Careful assessment of pregnant women is imperative for proper counselling and management.
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Qadir, Sidra, Maria Younas, Amina Aftab, Sadiq Jan, Muhammad Aiman Waleed Khan, and Muhammad Adil Hadeed Khan. "Frequency of Ultrasonographically Detectable Fetal Anomalies in Pregnancies Complicated by Polyhydramnios." Pakistan Journal of Medical and Health Sciences 17, no. 6 (2023): 404–6. http://dx.doi.org/10.53350/pjmhs2023176404.
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Introduction: The diagnosis of polyhydramnios is made prenatally by ultrasound examination using a noninvasive qualitative or quantitative approach. Ultrasound is well suited to assess liquor status and assess amniotic fluid volume. It is non- invasive, easily performed test and had no adverse effects on fetus and mother. 3.5 MHz convex ultrasound transducer (probe) is used to perform sonography, with use of Color Doppler whenever necessary. Objectives: To find out the frequency of ultrasonographically detectable fetal anomalies in pregnancies complicated by polyhydramnios. Study design: Cross sectional study Settings: Radiology Department of PAF Hospital Islamabad. Study duration: 6th October 2020 to 5th April 2021 Materials & Methods: A total of 150 women 20 to 40 years old having polyhydramnios during their second or third trimester of pregnancy were included. Patients with multiple gestation and intrauterine fetal death were excluded. They were scanned in detail with ultrasound machine having a convex 3.5 MHz probe for the severity of Amniotic Fluid Index (AFI) and for congenital fetal anomalies. Patients’ demographics and clinical characteristics were recorded. Results: Age range in this study was from 20 to 40 years with mean age of 28.87±4.16 years. Majority of the patients 92 (61.33%) were between 20 to 30 years of age. Mean gravidity was 3.01 ± 0.99. Mean duration since marriage was 5.50 ± 1.22 years. In this study, frequency of ultrasonographically detectable fetal anomalies in pregnancies complicated by polyhydramnios was found to be 38 (25.33%). Conclusion: This study concluded that frequency of ultrasonographically detectable fetal anomalies in pregnancies complicated by Polyhydramnios is quite high. Keywords: polyhydramnios, fetal anomalies, ultrasonography
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Preda, Agnesa, Adela Gabriela Ștefan, Silviu Daniel Preda, et al. "Transient Polyhydramnios during Pregnancy Complicated with Gestational Diabetes Mellitus: Case Report and Systematic Review." Diagnostics 12, no. 6 (2022): 1340. http://dx.doi.org/10.3390/diagnostics12061340.
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Polyhydramnios is an obstetrical condition defined as a pathological increase in the amniotic fluid and is associated with a high risk of maternal-fetal complications. Common causes of polyhydramnios include fetal anatomical and genetic abnormalities, gestational diabetes mellitus, and fetal viral infections. We present the case of a 30-year-old Caucasian woman with transient polyhydramnios associated with gestational diabetes mellitus and obstetric complications. The diagnosis was based on the ultrasound assessment of amniotic fluid volume during a common examination at 26 weeks. Two weeks prior, the patient had been diagnosed with gestational diabetes mellitus. After 4 days, the patient was examined, and the amniotic fluid index returned to normal values. At 38 weeks, the patient presented to the emergency room due to lack of fetal active movement. Ultrasound revealed polyhydramnios, the patient was admitted for severe fetal bradycardia, and fetal extraction through emergency cesarian section was performed. Six weeks after birth, the patient underwent an oral glucose tolerance test with normal values, confirming gestational diabetes mellitus. We performed a systematic review of the literature on polyhydramnios, from January 2016 to April 2022, to analyze all recent published cases and identify the most common etiological causes and important aspects related to maternal-fetal outcomes.
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Qadir, Maimoona. "POLYHYDRAMNIOS; FETOMATERNAL OUTCOME OF POLYHYDRAMNIOS; A CLINICAL STUDY IN A TERTIARY CARE INSTITUTE." PROFESSIONAL MEDICAL JOURNAL 24, no. 12 (2017): 1889–93. http://dx.doi.org/10.17957/tpmj/17.4135.
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Nalini, I. Anand, Nayak Trupti, Gandhi Mona, and B. Kakadiya Mayuri. "A Prospective Study of Incidence, Causes and Management of Polyhydramnios at Tertiary Care Center." International Journal of Pharmaceutical and Clinical Research 16, no. 10 (2024): 1075–80. https://doi.org/10.5281/zenodo.14065328.
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<strong>Introduction:</strong> Polyhydramnios is a condition defined as a pathological increase in the volume of amniotic fluid during pregnancy. Common causes of polyhydramnios include gestational diabetes, congenital gastrointestinal anomalies like cleft palate, tracheoesophageal fistula, duodenal atresia, foetal infections, and others. Diagnosis is made via ultrasound, and the prognosis depends on the cause and severity. Mild forms often remain asymptomatic, while moderate to severe cases can result in complications such as maternal breathlessness, preterm labour, and premature rupture of membranes (PROM), cord prolapse, and postpartum haemorrhage (PPH). <strong>Aim:</strong> This study was conducted to investigate the incidence, causes, and management of polyhydramnios. <strong>Materials and Methods:</strong> We studied 106 clinically suspected cases of polyhydramnios beyond 28 weeks of gestation at M.P. Shah Medical College and G.G. Government Hospital, Jamnagar. All cases underwent ultrasonography for fetal surveillance and amniotic fluid index (AFI) calculation. <strong>Results:</strong> The results of our study revealed that 49.06% of polyhydramnios cases were idiopathic, followed by 24.53% linked to gestational diabetes and 16.98% associated with fetal anomalies. Multiple pregnancies and Rh isoimmunization accounted for 5.66% and 3.77% of cases, respectively. Primigravida patients comprised 59.3% of the study population, indicating a higher prevalence of polyhydramnios in first-time mothers. Management of gestational diabetes was employed in 24.53% of cases, while 7.54% required reductive amniocentesis, and 0.94% were treated with indomethacin. Vaginal delivery was achieved in 79.2% of cases, while cesarean sections accounted for 20.8%, demonstrating that despite complications, the majority of patients could deliver vaginally with proper management. <strong>Conclusion:</strong> In conclusion, most cases of polyhydramnios are idiopathic, with gestational diabetes and fetal anomalies being significant contributors to severe cases. Individualized management, timely screening, and monitoring are essential to ensure optimal outcomes, with delivery at tertiary care centers recommended for better maternal and fetal care.
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Shomaila, Romana Bibi, Shahinda, Salma, Nayyab Qayyum, and Laila Khan. "Frequency of Malpresentation in Patients Presenting with Polyhydramnios during Pregnancy at Tertiary Care Hospital." Journal of Gandhara Medical and Dental Science 10, no. 4 (2023): 49–51. http://dx.doi.org/10.37762/jgmds.10-4.478.
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OBJECTIVES To determine the frequency of malpresentation in pregnant women with polyhydramnios. METHODOLOGY This Cross-Sectional Study was conducted at the Department of Obstetrics and Gynecology of Lady Reading Hospital, Peshawar, from March 2021 to September 2021. A total of 175 pregnant women with polyhydramnios were included in the study. Ultrasound was done to make a diagnosis of malpresentation. RESULTSThe age range of pregnant women in this study was from 18-40 years with a mean age of 31.137±3.67 years, mean gestational age of 34.022±2.78 weeks, mean parity of 2.537±1.69 and mean AFI level was 29.017±2.32 cm. A previous history of malpresentation was seen in 25.7% of patients. Malpresentation was observed in 10.3% of patients. The previous history of malpresentation and polyhydramnios had strong statistical significance with current malpresentation (p<0.01). CONCLUSION With the timely diagnosis of polyhydramnios with documentation on ultrasound by an expert radiologist and clinical examination by a gynaecologist, malpresentation can be reduced significantly by prompt treatment.
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Anshu and Sinha Anupama. "Pregnancy and its Outcome with Special Reference to Oligohydramnios and Polyhydramnios : A Cross-Sectional Study." International Journal of Pharmaceutical and Clinical Research 16, no. 6 (2024): 1940–44. https://doi.org/10.5281/zenodo.12748458.
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<strong>Background: </strong>The importance of amniotic fluid volume as an indicator of fetal wellbeing has made its assessment an important part of antenatal fetal surveillance, also the level of amniotic fluid affect the fetal wellbeing, so the present study was conducted to study the pregnancy and its outcome with special reference to oligohydramnios and polyhydramnios. <strong>Methods: </strong>We studied 200 clinically suspected cases of oligohydramnios and polyhydramnios of more than 28 weeks of gestational age at Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College & Hospital, Bhagalpur, Bihar. All these clinically suspected patients were further examined by ultrasonography for fetal surveillance, AFI calculation and confirmation of amniotic fluid level abnormality. <strong>Result: </strong>The study revealed that predisposing factors and complications associated with oligohydramnios were – post term pregnancies, PROM, PIH, chronic abruption placentae while for polyhydramnios they were preeclampsia, PROM, preterm labour, abruption placentae, malpresentation. There were no maternal high-risk factors seen in oligohydramnios, but polyhydramnios was observed with anemia, Rh factor incompatibility, PIH, gestational diabetes mellitus and multifetal gestation. The proportion of C-section for fetal distress was higher in oligohydramnios. <strong>Conclusion: </strong>We concluded from this study that there were many predisposing factors for both oligohydramnios and polyhydramnios they should be addressed judiciously to reduce their higher proportion. Hence it is essential to evaluate amniotic fluid volume during ante partum fetal surveillance, while maternal examination should look for high risk factors to avoid untoward complications beforehand. Thus, management of women with oligohydramnios and polyhydramnios should be indivisualised with careful monitoring during labour, judicious and active intervention timely gives margin of safety.
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Dubas, L. G. "Biochemical markers and effectivity of the preventive therapy of the fetal distress and preterm delivery in pregnant women with polyhydramnios." Reports of Vinnytsia National Medical University 23, no. 3 (2019): 465–74. http://dx.doi.org/10.31393/reports-vnmedical-2019-23(3)-21.
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Polyhydramnios in pregnant women are one of the most frequent pathologies in obstetrics, which is caused by an increase in the use of ultrasound screening of pregnant women and ranges from 1–3 to 8%. The aim of the study was to evaluate changes in blood biochemical parameters, biophysical profile of the fetus and the health status of newborns in pregnant women with polyhydramnios during the prophylactic therapy of this pathology and to estimate the frequency of polyhydramnios occurrence under the influence of preventive therapy in pregnant women at risk of polyhydramnios. We examined 120 pregnant women at gestational age from 20 to 38 weeks between the ages of 20 and 39 years: 1 group consisted of 30 healthy pregnant women, 2 group — 90 pregnant women with chronic polyhydramnios, which was divided into two subgroups: 40 pregnant women without fetal distress in 1 subgroup and 50 pregnant women with fetal distress in 2 subgroups. 1 subgroup of pregnant women received prophylactic Magnerot, Tivortin, Larnamine, Lymphomyosot and vitamin D3. The 2nd subgroup of pregnant women received traditional treatment according to the clinical protocol of the Ministry of Health of Ukraine №900 dated December 27, 2006, №782 dated December 29, 2005. Prenatal diagnosis was carried out by the method of enzyme-linked immunosorbent assay: the metabolite level of vitamin D-25 OH(D) was determined, anti-inflammatory cytokines IL–10, IL–6, vascular endothelial growth factor VEGF, malonic aldehyde, carbonyl groups of proteins, superoxide dismutase, serum protein content. Conducted ultrasound examination of the fetus and dopplerometry of uterine-placental vessels, cardiotocography of the fetus, evaluated the biophysical profile of the fetus. The significance of the difference between the compared groups was determined using Student's t test. In pregnant women with chronic polyhydramnios, a decrease in endogenous glutathione antioxidant reserves, a decrease in the activity of the superoxide dismutase antioxidant enzyme, an increase in the activity of the pro-oxidant enzyme xanthine oxidase and the presence of cytokine imbalance have been found. It is shown that among all biochemical changes in the body of pregnant women with chronic polyhydramnios, vitamin D deficiency, inflammation and disturbance of angiogenesis play the most important role in the development of fetal distress. Pregnant women at high risk of polyhydramnios who received the proposed preventive therapy for fetal distress, improved fetoplacental blood flow, decreased the percentage of placental dysfunction by 1.8 times, fetal distress — by 1.5 times, premature birth — by 2 times, decreased asphyxia in newborns 1.7 times, the rate of perinatal morbidity in newborns decreased 1.9 times, compared with the group of pregnant women receiving traditional therapy. Thus, the positive effect of preventive therapy of pathology of pregnant women with polyhydramnios was confirmed clinically and biochemically.
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S, V. Mobeentaj, Prathima P., and N. Ananya. "A Prospective Observational study of outcome of pregnancy and perinatal outcome in Amniotic Fluid Index of more than or equal to 18cm Polyhydramnios in Term Pregnancy." International Journal of Pharmaceutical and Clinical Research 16, no. 4 (2024): 800–804. https://doi.org/10.5281/zenodo.11179880.
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<strong>Background: </strong>The amniotic fluid begins to develop from the mother’s plasma through a process called transudation. Its quantity varies over the course of the pregnancy. Throughout the intrauterine life, the amniotic fluid serves a number of purposes. The amniotic fluid index (AFI), the most popular ultrasonography technique for the identification of amniotic fluid, has been proposed in 1987 by J.P. Phelan and colleagues. AFI greater than the 95<sup>th</sup> percentile for gestational age is considered a polyhydramnios. The severity of polyhydramnios is inversely correlated with the probability of congenital malformations and perinatal mortality. Aim of the study is to study the obstetric outcome in pregnancies with polyhydramnios; to determine the maternal and perinatal outcome in pregnancies complicated by polyhydramnios; to determine the possible factors causing polyhydramnios. <strong>Methodology: </strong>This was a Prospective Observational study done in 100 cases over 2 years period in the Department of OBG, Government General Hospital. <strong>Inclusion Criteria: </strong>Singleton pregnancies with gestational age 37 – 40 weeks and AFI >18cm. <strong>Exclusion Criteria: </strong>Multiple gestations, < 18 cm AFI, < 37 or > 40 weeks gestation. <strong>Results: </strong>Idiopathic polyhydramnios was the common type, followed by gestational diabetes and congenital anomalies. PROM was major problem during the labor.No maternal mortality was noted but a 7% perinatal mortlality was noted and the majority of the deaths were due to respiratory distress. <strong>Conclusion: </strong>In all cases with abnormal liquor volume, a thorough history, clinical examination, and relevant investigations should be performed to identify the various etiological factors in order to improve the prognosis for the foetus and prevent any complications for the mother.
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Yang, Hong, Chanyun Xiao, and Jiahui Tu. "The effect of gestational diabetes mellitus on pregnancy outcomes in advanced primiparous women: A retrospective study." Medicine 103, no. 13 (2024): e37570. http://dx.doi.org/10.1097/md.0000000000037570.
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Gestational diabetes mellitus (GDM) could have a variable degree of adverse effects on pregnancy outcomes for both pregnant women and newborns. The purpose of the study was to explore the effect of GDM on pregnancy outcomes in advanced primiparous women. A total of 1076 advanced primiparous women were included between January 2020 and December 2022. All these women were divided into the GDM group (n = 434) and the non-GDM group (n = 642). Variables included baseline characteristics, maternal, and newborn outcomes were collected. The risk of each adverse outcome was analyzed by multivariate logistic regression models. The effect of blood glucose control on pregnancy outcomes was further analyzed among GDM women with good glycaemic control (n = 381) and poor glycaemic control (n = 53). Analysis of baseline characteristics demonstrated a significant difference in prepregnancy body mass index (median, IQR: 22.27 [20.58–24.44] vs 21.17 [19.53–22.86], P < .01) between the GDM group and the non-GDM group. A significantly higher incidence rate of adverse pregnancy outcomes was found in advanced primiparous women with GDM, such as polyhydramniosis, premature birth, low-birth weight, macrosomia, and neonatal intensive care unit admission (all P < .05). Compared with the non-GDM group, the risk of polyhydramniosis was nearly twice as high in the GDM group (adjusted odds ratio: 1.94, 95% confidence interval: 1.01–3.72, P = .04) after adjusted baseline characteristics. Among the GDM group, the women with poor glycaemic control showed a significantly higher incidence rate of polyhydramnios, hypertensive disorders of pregnancy, cesarean delivery, premature birth, low-birth weight, macrosomia, and neonatal intensive care unit admission was significant than the women with good glycaemic control (all P < .05). GDM was an independent risk factor for polyhydramnios in advanced primiparous women. At the same time, good glycaemic control in diabetics advanced primiparous women could reduce adverse pregnancy outcomes.
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Berezowsky, Alexandra, Eran Ashwal, Liran Hiersch, Yariv Yogev, and Amir Aviram. "Transient Isolated Polyhydramnios and Perinatal Outcomes." Ultraschall in der Medizin - European Journal of Ultrasound 40, no. 06 (2018): 749–56. http://dx.doi.org/10.1055/a-0645-1136.
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Abstract Purpose To evaluate labor and perinatal outcomes of transient isolated polyhydramnios. Materials and Methods A retrospective cohort study (2008–2013) at a university-affiliated, tertiary medical center. Eligibility was limited to patients with singleton gestations, no maternal diabetes or known structural/chromosomal anomalies, and no rupture of the membranes prior to delivery, at > 34 weeks of gestation. All women underwent routine sonogram for estimation of fetal weight (sEFW) between 28–34 weeks of gestation, and a second routine sonogram at admission. We compared women diagnosed with polyhydramnios at the time of the sEFW which later resolved, with women who had normal AFI during the sEFW. Results Overall, 44 263 women delivered during this time period, of which 292 (0.7 %) with transient polyhydramnios (study group) and 29 682 with a normal amniotic fluid level (control group) were eligible for analysis. Women with transient polyhydramnios had a higher risk for assisted vaginal delivery (AVD), mainly due to abnormal/intermediate fetal heart rate tracings (aOR 2.3, 95 % CI 1.2–5.5), and a higher risk for cesarean delivery (CD), mostly because of labor dystocia (aOR 2.5, 95 % CI 1.2–5.1 for 1st stage arrest and aOR 3.4, 95 % CI 1.6–7.2) for 2nd stage arrest), suspected macrosomia (aOR 3.2, 95 % CI 1.6–6.6) and malpresentation (aOR 6.6, 95 % CI 2.0–21.1). Conclusion Transient isolated polyhydramnios detected during the sonogram at 28–32 weeks of gestation is an independent risk factor for the need for obstetrical intervention during labor.
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Sami, Aqeela, Jawad Jalil, Muhammad Sarfraz, Jawad ul Hassan, Ruhma Khawar, and Zahra Mumtaz. "Neonatal Outcome of Pregnancies with Oligohydramnios and Polyhydramnios." Pakistan Armed Forces Medical Journal 73, no. 3 (2023): 833–36. http://dx.doi.org/10.51253/pafmj.v73i3.8643.
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Objective: To asses’ factors associated with neonatal outcome of pregnancies with oligohydramnios and polyhydramnios.
 Study Design: Comparative Cross-sectional Study.
 Place and Duration of Study: Department of Pediatrics and Gynecology, Fauji Foundation Hospital, Lahore Pakistan, from Oct 2020 to Sep 2021
 Methodology: A prospective comparative study was conducted on the babies born to mothers diagnosed witholigohydramnios and polyhydramnios during the course of pregnancy. Neonates were evaluated by neonatologist within first 24 hours of birth. The cases were admitted and well babies were handed over to parents. The neonatal outcome parameters were observed in all these babies for first two weeks of life. Those who lost follow up they were excluded from study. Age of mother, gestational age of baby, maternal hypertension and maternal diabetes were associated with presence of complications among these babies.
 Results: Two thousand One hundred and Twenty-nine deliveries took place in given duration. About 322 had either polyhydramnios or oligohydramnios. About 150 cases could be followed completely. Fifty-five (36.7%) showed presence of one or more complications, of which 29(41.4%) cases had oligohydramnios and 26(32.5%) had polyhydramnios. Maternal age and presence of maternal diabetes and maternal hypertension had statistically significant association with complications in neonates (p-value <0.005).
 Conclusion: Complications rate was high among neonates born to mothers with oligohydramnios or polyhydramnios. Advanced maternal age, presence of diabetes mellitus and hypertension were factors association with presence of complications in neonates included in our study.