Relevant bibliographies by topics / Polymeric micelles Doxorubicin Drug

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Academic literature on the topic 'Polymeric micelles Doxorubicin Drug'

Author: Grafiati
Published: 2 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Polymeric micelles Doxorubicin Drug"

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Wang, Jing, Xueqing Xing, Xiaocui Fang, et al. "Cationic amphiphilic drugs self-assemble to the core–shell interface of PEGylated phospholipid micelles and stabilize micellar structure." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 371, no. 2000 (2013): 20120309. http://dx.doi.org/10.1098/rsta.2012.0309.

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Since polymeric micelles are promising and have potential in drug delivery systems, people have become more interested in studying the compatibility of polymeric carriers and drugs, which might help them to simplify the preparation method and increase the micellar stability. In this article, we report that cationic amphiphilic drugs can be easily encapsulated into PEGylated phospholipid (PEG–PE) micelles by self-assembly method and that they show high encapsulation efficiency, controllable drug release and better micellar stability than empty micelles. The representative drugs are doxorubicin
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Zhang, Yixin, Song Luo, Yan Liang, et al. "Synthesis, characterization, and property of biodegradable PEG-PCL-PLA terpolymers with miktoarm star and triblock architectures as drug carriers." Journal of Biomaterials Applications 32, no. 8 (2018): 1139–52. http://dx.doi.org/10.1177/0885328217751247.

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A series of amphiphilic terpolymers with miktoarm star and triblock architectures of poly(ethylene glycol) (PEG), poly(ε-caprolactone) (PCL) and poly(l-lactide acid) (PLLA) or poly(DL-lactide acid) (PDLLA) terpolymers were synthesized as carriers for drug delivery. The architecture, molecular weight and crystallization behavior of the terpolymers were characterized. Anticancer drug doxorubicin was encapsulated in the micelles to investigate their drug loading properties. The miktoarm star terpolymers exhibited stronger crystallization capability, smaller size and better stability than that of
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Zhang, Hai, Jianqin Yan, Heng Mei, et al. "High-drug-loading capacity of redox-activated biodegradable nanoplatform for active targeted delivery of chemotherapeutic drugs." Regenerative Biomaterials 7, no. 4 (2020): 359–69. http://dx.doi.org/10.1093/rb/rbaa027.

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Abstract Challenges associated with low-drug-loading capacity, lack of active targeting of tumor cells and unspecific drug release of nanocarriers synchronously plague the success of cancer therapy. Herein, we constructed active-targeting, redox-activated polymeric micelles (HPGssML) self-assembled aptamer-decorated, amphiphilic biodegradable poly (benzyl malolactonate-co-ε-caprolactone) copolymer with disulfide linkage and π-conjugated moieties. HPGssML with a homogenous spherical shape and nanosized diameter (∼150 nm) formed a low critical micellar concentration (10−3 mg/mL), suggesting good
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Wen, Weiqiu, Chong Guo, and Jianwei Guo. "Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery." Nanomaterials 11, no. 1 (2021): 188. http://dx.doi.org/10.3390/nano11010188.

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Four-arm star-shaped (denoted as ‘S’) polymer adamantane-[poly(lactic-co-glycolic acid)-b-poly(N,N’-diethylaminoethyl methacrylate) poly(ethylene glycol) monomethyl ether]4 (S-PLGA-D-P) and its linear (denoted as ‘L’) counterpart (L-PLGA-D-P) were synthesized, then their self-assembled micelles were further developed to be platforms for anticancer drug delivery. Two types of polymeric micelles exhibited strong pH-responsiveness and good drug loading capacity (21.6% for S-PLGA-D-P and 22.9% for L-PLGA-D-P). Using doxorubicin (DOX) as the model drug, their DOX-loaded micelles displayed well cont
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Zhou, Xin Xin, Long Jin, Rui Qun Qi, and Teng Ma. "pH-responsive polymeric micelles self-assembled from amphiphilic copolymer modified with lipid used as doxorubicin delivery carriers." Royal Society Open Science 5, no. 3 (2018): 171654. http://dx.doi.org/10.1098/rsos.171654.

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In the present study, a novel pH-responsive amphiphilic copolymer, 1,2-distearoyl- sn -glycero-3-phosphoethanolamine- N -[methoxy(polyethylene glycol)] conjugated poly(β-amino esters) (DSPE- b -PEG- b -PAE- b -PEG- b -DSPE), was designed and successfully synthesized via Michael-type step polymerization. The chemical structure of the pentablock copolymer was confirmed with proton nuclear magnetic resonance ( 1 H-NMR) and Fourier transform infrared (FT-IR) spectroscopy. The copolymer was able to self-assemble into core/shell polymeric micelles in aqueous solution at low concentrations, and its c
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Emami, Jaber, Moloud Kazemi, and Mina Mirian. "Synthesis and in vitro evaluation of self-assembling biocompatible heparin-based targeting polymeric micelles for delivery of doxorubicin to leukemic cells." Research in Pharmaceutical Sciences 20, no. 1 (2025): 142–64. https://doi.org/10.4103/rps.rps_197_24.

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Background and purpose: Biodegradable polymeric micelles have emerged as one of the most promising platforms for targeted drug delivery. In the present study, a polymeric micelle composed of folic acid (FA), heparin (HEP), dexamethasone (DEX), and (FA-PEG-HEP-CA-TOC) was developed for the delivery of doxorubicin (DOX) to leukemic cells. Experimental approach: FA-HEP-DEX was synthesized and characterized by 1H-NMR. DOX-loaded micelles were prepared using a dialysis method. The impact of various processing variables, including polymer-to-drug ratio, dialysis temperature, and solvent type, on the
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Romero, Jocelyn Fernanda, Svenja Herziger, Mariam Cherri, et al. "Dendritic Glycerol-Cholesterol Amphiphiles as Drug Delivery Systems: A Comparison between Monomeric and Polymeric Structures." Pharmaceutics 15, no. 10 (2023): 2452. http://dx.doi.org/10.3390/pharmaceutics15102452.

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The application of micelles as drug delivery systems has gained a great deal of attention as a means to overcome the current several drawbacks present in conventional cancer treatments. In this work, we highlight the comparison of polymeric and monomeric amphiphilic systems with a similar hydrophilic–lipophilic balance (HLB) in terms of their biocompatibility, aggregation behavior in aqueous solution, and potential in solubilizing hydrophobic compounds. The polymeric system consists of non-ionic polymeric amphiphiles synthesized via sequential RAFT polymerization of polyglycerol first-generati
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Jiang, Junting, Junbo Li, Biyu Zhou, et al. "Fabrication of Polymer Micelles with Zwitterionic Shell and Biodegradable Core for Reductively Responsive Release of Doxorubicin." Polymers 11, no. 6 (2019): 1019. http://dx.doi.org/10.3390/polym11061019.

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To achieve a high stability in physiological environment and rapid intracellular drug release, a biodegradable zwitterionic triblock copolymer with a disulfide-linked poly-ε-caprolactone and polycarboxybetaine methacrylate (PCBMA-SS-PCL-SS-PCBMA) was prepared for micellar carrier to delivery doxorubicin (DOX) into tumor cells. PCBMA-SS-PCL-SS-PCBMA was obtained by following steps: i) introducing disulfide bonds through end-group modification of PCL diol with cystamine dihydrochloride; ii) preparing PCL-RAFT macromolecular chain transfer agent by EDC/NHS chemistry; iii) RAFT polymerization of z
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Ramesh, Kalyan, Avnish Kumar Mishra, Jin Kon Kim, Yeon Tae Jeong, Yeong-Soon Gal, and Kwon Taek Lim. "Preparation of Doxorubicin-Loaded Amphiphilic Poly(D,L-Lactide-Co-Glycolide)-b-Poly(N-Acryloylmorpholine) AB2 Miktoarm Star Block Copolymers for Anticancer Drug Delivery." Materials 13, no. 17 (2020): 3713. http://dx.doi.org/10.3390/ma13173713.

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Owing to their unique topology and physical properties, micelles based on miktoarm amphiphilic star block copolymers play an important role in the biomedical field for drug delivery. Herein, we developed a series of AB2-type poly(D,L-lactide-co-glycolide)-b-poly(N-acryloyl morpholine) (PLGA-b-PNAM2) miktoarm star block copolymers by reversible addition–fragmentation chain–transfer polymerization and ring-opening copolymerization. The resulting miktoarm star polymers were investigated by 1H NMR spectroscopy and gel permeation chromatography. The critical micellar concentration value of the mice
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Choi, Young, Eun-sook Choi, Kwan Mun, et al. "Dual-responsive Gemini Micelles for Efficient Delivery of Anticancer Therapeutics." Polymers 11, no. 4 (2019): 604. http://dx.doi.org/10.3390/polym11040604.

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Polymeric micelles as drug delivery vehicles are popular owing to several advantages. In this study, a gemini amphiphile (gemini mPEG-Cys-PMT) consisting of hydrophilic poly(ethylene glycol) and hydrophobic poly(methionine) with cystine disulfide spacer was synthesized and its micellar properties for thiol- or reactive oxygen species (ROS)-dependent intracellular drug delivery were described. The cleavage of cystine linkage in a redox environment or the oxidation of methionine units in a ROS environment caused the destabilization of micelles. Such redox- or ROS-triggered micellar destabilizati
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Dissertations / Theses on the topic "Polymeric micelles Doxorubicin Drug"

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Teng, Yue. "Solubilization and release studies of small molecules in polymeric micelles /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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Master, Alyssa M. "EGFR-Targeted Polymeric Micelles For Targeted Pc 4-PDT Of Oropharyngeal Tumors." Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1364833269.

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Pawlish, Gerald Joseph. "TAILORING DRUG-CARRIER INTERACTIONS IN POLY(SIALIC ACID) MICELLES FOR USE AS CANCER THERAPEUTIC CARRIERS." Diss., Temple University Libraries, 2018. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/519673.

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Bioengineering<br>Ph.D.<br>Although great progress has been made, cancer still remains one of the most prevalent maladies plaguing mankind. New treatment methodologies using nanoparticles have come to the forefront by allowing for enhanced delivery of therapeutics to the tumor site. The design of the nanoparticle should allow for long circulation times, tumor-specific targeting and efficient release at the site of action. This requires that both the external shell and internal core of the nanoparticle be carefully selected to meet the maximal criteria of each of these steps. Poly(sialic acid)
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Mishra, Kaushik. "Folate Receptor-Targeted Polymeric Micellar Nanocarriers as Drug Delivery Systems." University of Akron / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=akron1629218263972419.

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Hans, Meredith L. Lowman Anthony M. "Synthesis, characterization, and application of biodegradable polymeric prodrug micelles for long-term drug delivery /." Philadelphia, Pa. : Drexel University, 2006. http://dspace.library.drexel.edu/handle/1860/741.

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Brunato, Silvia. "Biocompatible modular nanovectors for anticancer drug delivery and controlled release." Doctoral thesis, Università degli studi di Padova, 2018. http://hdl.handle.net/11577/3425395.

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The research project of this PhD thesis was focused on the design and development of innovative “smart” nanosystems for a controlled anticancer drug delivery. Smart drug delivery systems have emerged as a strategy to achieve enhanced site-specific drug accumulation and control release within the desired tissue, thus offering the opportunity to reduce systemic side effects caused by an unspecific drug biodistribution. Among the several colloidal systems available, polymeric micelles formed by amphiphilic polyaminoacidic block copolymers are gaining relevance for therapeutic application as the
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Lavrador, Pedro Oliveira. "Development of drug-loaded polymeric nanomicelles for stem cell osteogenic differentiation." Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22832.

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Mestrado em Bioquímica Clínica<br>As doenças musculoesqueléticas afetam atualmente uma grande percentagem da população mundial sendo esperado que a sua prevalência venha a aumentar no futuro. De entre as abordagens terapêuticas atualmente aplicadas a nível clínico para as patologias ou danos ósseos, a utilização de terapias celulares baseadas em células estaminais mesenquimais humanas (hMSCs) surge como uma das mais promissoras devido à capacidade de diferenciação das hMSCs em células do tecido esquelético. No entanto, a diferenciação destas células em células osteoprogenitoras tem sido
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Diaz, Mario Alfonso. "High-Frequency Ultrasound Drug Delivery and Cavitation." BYU ScholarsArchive, 2007. https://scholarsarchive.byu.edu/etd/1050.

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The viability of a drug delivery system which encapsulates chemotherapeutic drugs (Doxorubicin) in the hydrophobic core of polymeric micelles and triggers release by ultrasound application was investigated at an applied frequency of 500 kHz. The investigation also included elucidating the mechanism of drug release at 70 kHz, a frequency which had previously been shown to induce drug release. A fluorescence detection chamber was used to measure in vitro drug release from both Pluronic and stabilized micelles and a hydrophone was used to monitor bubble activity during the experiments. A threshol
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Wek, Kristen S. "Development of Polymeric Therapeutic Nanoparticles: Toward Targeted Delivery and Efficient 19F MRI of Solid Tumors." Case Western Reserve University School of Graduate Studies / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=case1491168123379844.

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Alqarni, Ali. "Solubility Ratios, Encapsulation Efficiency, and Size of Beta-sitosterol Loaded Poly(Lactide)-Block-Poly(Ethylene glycol) Polymeric Micelles." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 2019. http://digitalcommons.auctr.edu/cauetds/201.

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β-sitosterol/poly(ethylene glycol)-block-poly(lactic acid) (PLA-b-PEG) complexes were prepared by solution blending in purified water and ethanol. The mixture of water and ethanol is a suitable solvent system for the two components. The complex was studied by using Nuclear Magnetic Resonance (NMR) spectroscopy and Differential Scanning Calorimetry (DSC). β-sitosterol is a drug that may reduce the swelling of benign prostatic hyperplasia (BPH) and diminishing inflammation. However, it is hydrophobic and difficult to deliver in aqueous solution. Since PLA-b-PEG has amphiphilic properties, the co
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Books on the topic "Polymeric micelles Doxorubicin Drug"

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Kesharwani, Prashant, and Khaled Greish. Polymeric Micelles for Drug Delivery. Elsevier Science & Technology, 2022.

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Polymeric Micelles for Drug Delivery. Elsevier, 2022. http://dx.doi.org/10.1016/c2020-0-03290-1.

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Kesharwani, Prashant, and Khaled Greish. Polymeric Micelles for Drug Delivery. Elsevier Science & Technology, 2022.

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Book chapters on the topic "Polymeric micelles Doxorubicin Drug"

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Nishiyama, Nobuhiro. "Polymeric Micelles." In Cancer Drug Delivery Systems Based on the Tumor Microenvironment. Springer Japan, 2019. http://dx.doi.org/10.1007/978-4-431-56880-3_8.

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Wu, Wei, and Xiqun Jiang. "Polymeric Micelles for Drug Delivery." In Biomedical Nanomaterials. Wiley-VCH Verlag GmbH & Co. KGaA, 2016. http://dx.doi.org/10.1002/9783527694396.ch3.

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Paprikar, Anuja, Ankit Soni, Neeraj Kaushal, and Senshang Lin. "Polymeric Micelles for Drug Delivery." In Smart Nanomaterials in Biomedical Applications. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-84262-8_12.

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Vambhurkar, Ganesh, Naitik Jain, Dadi A. Srinivasarao, Paras Famta, Shashi Bala Singh, and Saurabh Srivastava. "Drug Solubilization and Drug Release from Polymeric Micelles." In Polymeric Micelles: Principles, Perspectives and Practices. Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-0361-0_5.

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Murthy, Rayasa S. Ramachandra. "Polymeric Micelles in Targeted Drug Delivery." In Advances in Delivery Science and Technology. Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-11355-5_16.

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Kwon, Glen S. "Polymeric Micelles for Multiple-Drug Delivery." In Nanostructure Science and Technology. Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-2305-8_7.

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Cammas, Sandrine, Yukio Nagasaki, Kazunori Kataoka, Teruo Okano, and Yasuhisa Sakurai. "Functional Polymeric Micelles: Synthesis and Characterization." In Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems. Springer Japan, 1996. http://dx.doi.org/10.1007/978-4-431-65883-2_98.

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Kim, Moon Suk, Hyun Hoon, Gilson Khang, and Hai Bang Lee. "Polymeric Nano Micelles as a Drug Carrier." In NanoScience in Biomedicine. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-49661-8_16.

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Chen, Huabing, Zhishen Ge, and Kazunori Kataoka. "Polymeric Micelles for Cancer-Targeted Drug Delivery." In Bioinspired and Biomimetic Polymer Systems for Drug and Gene Delivery. Wiley-VCH Verlag GmbH & Co. KGaA, 2014. http://dx.doi.org/10.1002/9783527672752.ch4.

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Guliy, Olga I., Alexander S. Fomin, Elena G. Zhnichkova, Sergey V. Kozlov, Sergey A. Staroverov, and Lev A. Dykman. "Polymeric Micelles for Targeted Drug Delivery Systems." In Nanotechnology in the Life Sciences. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-12658-1_18.

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Conference papers on the topic "Polymeric micelles Doxorubicin Drug"

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Sipos, Bence, and Ildikó Csóka. "Investigation of thermosensitive polymeric micelles in scope of nasal drug administration." In VI. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2024. http://dx.doi.org/10.14232/syrptbrs.2024.38.

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HAMANAKA, YOHEI, KOHSUKE GONDA, KOUICHI SHIRAISHI, MASAYUKI YOKOYAMA, MOTOHIRO TAKEDA, and NORIAKI OHUCHI. "IN VIVO REAL-TIME TRACKING OF POLYMERIC MICELLES FOR DRUG DELIVERY SYSTEM VISUALIZATION." In Proceedings of the Tohoku University Global Centre of Excellence Programme. IMPERIAL COLLEGE PRESS, 2012. http://dx.doi.org/10.1142/9781848169067_0070.

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Sipos, Bence, Márk Benei, Ildikó Csóka, and Gábor Katona. "Formulation of sustained release sodium alginate beads loaded with antidiabetic drug containing polymeric micelles." In V. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2023. http://dx.doi.org/10.14232/syrptbrs.2023.51.

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Dulken, Benjamin, Tae Hee Kim, Christopher Mount, Mengyuan Du, Wayne Gombotz, and Suzie Pun. "Abstract 4770: Delivery of doxorubicin to multi-drug resistant murine xenografts via drug-loaded micelles formed from mixtures of amphiphilic triblock copolymers." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4770.

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Lee, Sang Hyo, Jae Min Oh, Jin Soo Son, et al. "Preparation and characterization of polymeric micelles consisting of poly(propylene glycol) and poly(caprolactone) as a drug carrier." In 2010 IEEE 3rd International Nanoelectronics Conference (INEC). IEEE, 2010. http://dx.doi.org/10.1109/inec.2010.5424831.

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Bora, Larisa, Ștefana Avram, Lavinia Lia Vlaia, et al. "Oregano essential oil polymeric micelles-based hydrogel as a dermal drug delivery system: in vitro and in ovo assessment." In V. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2023. http://dx.doi.org/10.14232/syrptbrs.2023.52.

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Thedrattanawong, Chitinart, Chalaisorn Thanapongpibul, Pinunta Nittayacharn, and Norased Nasongkla. "Reduction the Initial-Burst Release of Doxorubicin from Polymeric Depot as a Local Drug Delivery System for Cancer Treatment." In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2018. http://dx.doi.org/10.1109/embc.2018.8513258.

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