Academic literature on the topic 'Polymorphic Forms'

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Journal articles on the topic "Polymorphic Forms"

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G, Nithya, Sudha R, and Charles C. Kanakam. "Polymorphic behavior of an organic compound." Asian Journal of Pharmaceutical and Clinical Research 10, no. 4 (2017): 259. http://dx.doi.org/10.22159/ajpcr.2017.v10i4.16702.

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Objective: Polymorphic crystals were exhibited in many organic compounds. The frequency changes, relative intensities, band contours, and numberof bands were observed in the spectra of different polymorphism which may be due to molecule-molecule interactions in the crystal unit cells. Theshape of a molecule at its site in the unit cell is distorted by molecular interactions.Methods: The identification of a pure crystal form and to quantify a mixture of two forms infrared and Raman spectra of different crystalline formsof the same organic compound can be used. 2’-chloro-4-methoxy-3-nitro benzil
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Kuzmin, V. S., V. V. Chernyshev, and A. I. Luttseva. "X-RAY POWDER DIFFRACTION IN QUALITY CONTROL OF MEDICINES." Bulletin of the Scientific Centre for Expert Evaluation of Medicinal Products 8, no. 3 (2018): 158–61. http://dx.doi.org/10.30895/1991-2919-2018-8-3-158-161.

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X-ray powder diffraction is one of the methods used for detection and analysis of polymorphic forms of pharmaceutical substances. The article elucidates the concept of polymorphism, briefly explains physical characteristics of this phenomenon, conditions of polymorphic transformations and the prevalence of polymorphic forms among drug substances. It should be noted that polymorphism is observed in drug substances belonging to different pharmacologic classes. Polymorphic forms of the same drug substance have different solubility, melting point, resistance to oxidation and to other destructive p
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Takeguchi, Seiya, Arisa Sato, Hironori Hondoh, Mio Aoki, Hidetaka Uehara та Satoru Ueno. "Multiple β Forms of Saturated Monoacid Triacylglycerol Crystals". Molecules 25, № 21 (2020): 5086. http://dx.doi.org/10.3390/molecules25215086.

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We have investigated the polymorphism of triacylglycerol (TAG) crystals as they affect the qualities such as shelf life, mouth feel, and texture of chocolate and other products. Saturated monoacid TAGs, like trilaurin, are considered as models for TAG crystallization; however, there is still debate about the number of their polymorphs that exist. In this study, we characterized a set of novel polymorphs, β forms of saturated monoacid TAGs, which were obtained via different pathways depending on the crystallization history, by polarized light microscopy, X-ray diffraction, and differential scan
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Rajendrakumar, Satyasree, Anuja Surampudi Venkata Sai Durga, Jagadeesh Babu Nanubolu, and Sridhar Balasubramanian. "Two novel polymorphic forms of iron-chelating agent deferiprone." Acta Crystallographica Section C Structural Chemistry 76, no. 2 (2020): 193–200. http://dx.doi.org/10.1107/s2053229620000959.

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Thalassemia is a genetic blood disorder requiring life-long blood transfusions. This process often results in iron overload and can be treated by an iron-chelating agent, like deferiprone (3-hydroxy-1,2-dimethylpyridin-4-one), C7H9NO2, in an oral formulation. The first crystal structure of deferiprone, (Ia), was reported in 1988 [Nelson et al. (1988). Can. J. Chem. 66, 123–131]. In the present study, two novel polymorphic forms, (Ib) and (Ic), of deferiprone were identified concomitantly with polymorph (Ia) during the crystallization experiments. Polymorph (Ia) was redetermined at low temperat
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Hsu, Cheng-Hung, Wen-Ting Ke, and Shan-Yang Lin. "Progressive Steps of Polymorphic Transformation of Gabapentin Polymorphs Studied by Hot-stage FTIR Microspectroscopy." Journal of Pharmacy & Pharmaceutical Sciences 13, no. 1 (2010): 67. http://dx.doi.org/10.18433/j3fs32.

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Purpose. The aim of this study was to determine the progressive processes of polymorphic transformation of different gabapentin (GBP) polymorphs by using hot-stage Fourier transform infrared (FTIR) microspectroscopy. Methods. Four polymorphs of GBP were previously prepared and then identified by differential scanning calorimetry (DSC), thermogravimetric (TG) analysis, FTIR microspectroscopy and X-ray powder diffractometry. A novel hot-stage FTIR microspectroscopic technique was used to investigate the progressive steps of polymorphic transformation of each GBP polymorph sealed within two piece
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Akune, Yoko, Risa Hirosawa, Atsushi Koseki, and Shinya Matsumoto. "Role of halogen substituents in a series of polymorphic 2,5-diamino-3,6-dicyanopyrazine derivatives with highly flexible groups." Zeitschrift für Kristallographie - Crystalline Materials 232, no. 5 (2017): 395–405. http://dx.doi.org/10.1515/zkri-2016-2007.

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AbstractThe crystal structures of the ortho-X-benzyl derivatives, where X=F, Cl, Br, I, and Me, of 2,5-bis(N,N-dibenzylamino)-3,6-dicyanopyrazine dyes (C34H24N6X4) were analysed to evaluate the effect of a systematic series of structures on the occurrence of polymorphism. Detailed crystal structure analysis indicated that the thermally stable forms of the polymorphic derivatives (Cl and Br derivatives) were close-packed, whereas those of the non-polymorphic derivatives (F and I derivatives) were stabilised by an intermolecular interaction involving the ortho-substituents. In the thermally meta
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Paczkowska, Magdalena, Gabriela Wiergowska, Andrzej Miklaszewski, et al. "The Analysis of the Physicochemical Properties of Benzocaine Polymorphs." Molecules 23, no. 7 (2018): 1737. http://dx.doi.org/10.3390/molecules23071737.

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The study was a pioneering attempt to assess the influence of the structural polymorphism (forms I, II, III) of benzocaine on its solubility, apparent solubility, and chemical stability, which are vital parameters for preformulation and formulation work. The impact of differences in the solubility of selected polymorphs of benzocaine on their permeability through artificial biological membranes (PAMPA system) was evaluated. The polymorphs of benzocaine were obtained by means of techniques commonly used for the preparation of various pharmaceutical dosage forms: ball milling, micro milling, and
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Ângelo, Marilene, Jennifer Jacon, Olimpia Maria Santos, et al. "Occurrence of polymorphism in famotidine raw materials." Acta Crystallographica Section A Foundations and Advances 70, a1 (2014): C1563. http://dx.doi.org/10.1107/s2053273314084368.

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Polymorphs are compounds with the same chemical composition, however the molecules are arranged in at least two different ways in the solid state. Famotidine is a histamine H2-receptor antagonist inhibitor of gastric secretion and widely used in gastric and duodenal ulcer disease. Two polymorphs are described for famotidine, A and B. The polymorph A is the most thermodynamically stable form and polymorph B is the kinetically favored form being marketed because it presents greater pharmacological activity. The aim of this study was to evaluate the occurrence of famotidine polymorphs in five raw
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So, Hee-Soo, and Shinya Matsumoto. "Three differently coloured polymorphs of 3,6-bis(4-chlorophenyl)-2,5-dipropyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione." Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials 75, no. 3 (2019): 414–22. http://dx.doi.org/10.1107/s2052520619004773.

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In this paper, the conformational polymorphism of a chlorinated diketopyrrolopyrrole (DPP) dye having flexible substituents in a non-hydrogen-bonding system is reported. The propyl-substituted DPP derivative (PR3C) has three polymorphic forms, each showing a different colour (red, orange and yellow). All polymorphs could be obtained concomitantly under various crystallization conditions. The results of the crystal structure analysis indicate that PR3C adopts different conformations in each polymorph. The packing effect caused by the difference in the arrangement of neighbouring molecules was f
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Czernek, Jiří, and Jiří Brus. "Polymorphic Forms of Valinomycin Investigated by NMR Crystallography." International Journal of Molecular Sciences 21, no. 14 (2020): 4907. http://dx.doi.org/10.3390/ijms21144907.

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A dodecadepsipeptide valinomycin (VLM) has been most recently reported to be a potential anti-coronavirus drug that could be efficiently produced on a large scale. It is thus of importance to study solid-phase forms of VLM in order to be able to ensure its polymorphic purity in drug formulations. The previously available solid-state NMR (SSNMR) data are combined with the plane-wave DFT computations in the NMR crystallography framework. Structural/spectroscopical predictions (the PBE functional/GIPAW method) are obtained to characterize four polymorphs of VLM. Interactions which confer a confor
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Dissertations / Theses on the topic "Polymorphic Forms"

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Alvin, Yeoh Chong Yeow. "Nucleation of polymorphic forms." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498979.

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In this PhD project, the solvent effects on polymorphism were studied. This was done using an enantiotropic compound. By working at the transition temperature of the compound, it allowed for the separation of supersaturation effects from that of the solvent. p-Aminobenzoic acid was chosen as the model compound. p-Aminobenzoic acid (PABA) is an enantiotropic compound with a transitior temperature of 24°C. It has two polymorphs, a needle shaped α-form which is stable above the transition temperature and a prismatic shaped β-form stable below the transition temperature.
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Bawa, Yasmin. "Solvent inclusion properties of triamterene crystal forms and solubility differences between roxithromycin polymorphic forms / Yasmin Bawa." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1469.

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Francis, Farzaana. "The photodecomposition of different polymorphic forms of 1,4-dihydropyridine channel blockers." Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/1496.

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1,4-Dihydropyridines (DHPs) are a classification of compounds used as calcium channel blockers in the treatment of various conditions. These compounds readily undergo photodegradation. The degradants produced have no pharmaceutical activity and render the drugs ineffective. DHPs also exhibit polymorphism. Nifedipine and Nimodipine are two such drugs. This study aimed to monitor the photodegradation of these two drugs and to establish the effect of particle size, polymorphism and β-Cyclodextrin (β-CD) on the rate of photodegradation. Different polymorphs (namely the amorphous and stable crystal
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Strydom, Schalk Johannes. "Characterisation and quantification of the polymorphic forms of stavudine / Schalk Johannes Strydom." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1548.

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Du, Plessis Carine. "Characterisation of polymorphic, pseudopolymorphic and amorphous forms of roxithromycin / Carine du Plessis." Thesis, North-West University, 2004. http://hdl.handle.net/10394/661.

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Roxithromycin is a relatively new, semisynthetic, macrolide antibiotic and an ether oxime derivative of erythromycin A, consisting of a 14-membered, macrocyclic, lactone ring. Roxithnrmycin has proven clinical efficacy in upper - and lower respiratory infections, ski - and soft tissue infections, urogenital - and orodental infections. Few literature was available on the physicochemical properties of roxithromycin during this study, whilst no documentation on polymorphism, pseudopolymorphism or amorphism of roxithromycin was found. The aim of this study therefore was to investigate the possibil
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Talhat, Amanda Makhpal. "Polymorphic forms of cocoa butter as a function of origin and processing conditions." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708422.

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Vogel, Reinhard [Verfasser], and Holger [Akademischer Betreuer] Stark. "The bacterial flagellum: modeling the dynamics of the elastic filament and its transition between polymorphic helical forms / Reinhard Vogel. Betreuer: Holger Stark." Berlin : Universitätsbibliothek der Technischen Universität Berlin, 2012. http://d-nb.info/1026483654/34.

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Jasti, Bhaskara Rao. "Characterization of polymorphic forms and in vitro release of etoposide from poly-DL-lactic and poly-DL-lactic-co-glycolic acid micromatrices." Scholarly Commons, 1995. https://scholarlycommons.pacific.edu/uop_etds/2654.

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Etoposide has been shown to be effective in the treatment of testicular and small-cell lung cancers, lymphoma, leukemia and Kaposi's sarcoma. Several clinical investigations have suggested that the prolonged maintenance of greater than 1 $\mu$g/ml concentration in plasma would provide better therapeutic response in patients. Thus use of a sustained/controlled release formulation of etoposide was indicated. This investigation focused on the potential for the development of a sustained/controlled release dosage form of etoposide for a 7-15 day delivery using selected polylactic and polylactic-co
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Zerbini, Ana Paula Navarro de Almeida. "Desenvolvimento e avaliação de minicomprimidos contendo atorvastatina cálcica." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/9/9139/tde-07102010-103628/.

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O objetivo do presente trabalho foi desenvolver e avaliar minicomprimidos obtidos a partir de quatro formas polimórficas de atorvastatina cálcica. Inicialmente foi realizada uma caracterização físico-química das amostras (amorfa e formas cristalinas I, VI e VIII), empregando-se os ensaios de dissolução intrínseca e solubilidade através dos métodos do disco rotacional e do equilíbrio, respectivamente. Na sequência, foi realizada a caracterização do estado sólido por difração de raios-x, DSC (differencial scanning calorimetry) e termogravimetria. Foi observado que o polimorfo VIII demonstrou mai
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Chavez, Krystle J. "Crystallization of pseudopolymorphic forms of sodium naproxen in mixed solvent systems." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/29759.

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Thesis (Ph.D)--Chemical Engineering, Georgia Institute of Technology, 2009.<br>Committee Chair: Rousseau, Ronald; Committee Member: Meredith, Carson; Committee Member: Prausnitz, Mark; Committee Member: Teja, Amyn; Committee Member: Wilkinson, Angus. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Books on the topic "Polymorphic Forms"

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Westwood, Margaret Clare. A study on the polymorphic forms of cimetidine. De Montfort University, 1998.

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G, Brittain H., ed. Polymorphism of pharmaceutical solids. 2nd ed. Informa Healthcare, 2009.

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G, Brittain H., ed. Polymorphism in pharmaceutical solids. M. Dekker, 1999.

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Scialpi, Angela, and Alessio Mengoni, eds. La PCR e le sue varianti. Firenze University Press, 2008. http://dx.doi.org/10.36253/978-88-6453-159-5.

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The book "La PCR e le sue varianti" is designed as a reference tool for those whose laboratory activities deal with methods based on nucleic acid amplification. The text provides the theoretical bases of the polymerase chain reaction (PCR) and its variants (e.g. RT-PCR, quantitative PCR, isothermic PCR) in a rapid and concise manner and describes the principal applications used for genetic identification and the study of genetic polymorphism, in the form of a protocol that can be easily consulted by the users.
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Bernstein, Joel. Polymorphism in Molecular Crystals. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780199655441.001.0001.

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First recognized in 1822, polymorphism of crystals is now a widely recognized and observed phenomenon, with both fundamental and commercial ramifications in disciplines and industries that study and utilize solid forms of matter. The purpose of this edition is to summarize and to bring up to date the current knowledge and understanding of polymorphism in molecular crystals, and to concentrate it in one source. The information has been gleaned from a wide variety (~2500) of sources in the open literature; however, because of the increasing commercial importance of the phenomenon, a significant
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Gephart, Werner; Witte, ed. The Sacred and the Law: The Durkheimian Legacy. Klostermann, 2017. http://dx.doi.org/10.5771/9783465142942.

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There is little doubt about the importance of Emile Durkheim’s work and the influence it had on the social sciences. His insights into the realms of normativity in particular remain an inspiring mine of information for theoretical reflection and empirical analyses. While his strengths, as we know nowadays, might not have always laid in systematic arguments, his main concerns have shaped the development of social thought in fundamental ways: the question of changing social bonds and the problem of integration; belief and unbelief in societal values; acceptance and rejection of the law, obligati
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Brittain, H. G. Polymorphism in Pharmaceutical Solids. Taylor & Francis Group, 1999.

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Buchanan, David A., and Alan Bryman. ‘Not another survey’. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198796978.003.0001.

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Research methods influence the nature of evidence that is collected, how that evidence is interpreted, styles of theorizing, and modes of reporting. David A. Buchanan and Alan Bryman argue that methods are not neutral. Unconventional methods give us new lenses and perspectives on traditional topics, and open up fresh lines of inquiry. The distinction between conventional and unconventional is blurred, and methodology can be unconventional on a number of dimensions. The roots and consequences of methodological conservatism are explored, and the trend towards ‘polymorphic’ (many forms) research
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Polymorphism of Pharmaceutical Solids, Second Edition (Drugs and the Pharmaceutical Sciences). 2nd ed. Informa Healthcare, 2009.

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Book chapters on the topic "Polymorphic Forms"

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Bernstein, Joel, and Jill MacAlpine. "Pharmaceutical Crystal Forms and Crystal-Form Patents: Novelty and Obviousness1." In Polymorphism in the Pharmaceutical Industry. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527697847.ch16.

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Stahl, P. H., Bertrand Sutter, Arnaud Grandeury, and Michael Mutz. "Alternative Solid Forms: Salts." In Polymorphism in the Pharmaceutical Industry. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527697847.ch2.

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Wouters, Johan, Dario Braga, Fabrizia Grepioni, Luc Aerts, and Luc Quéré. "Alternative Solid Forms: Co-crystals." In Polymorphism in the Pharmaceutical Industry. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527697847.ch3.

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Hilfiker, Rolf, Susan M. De Paul, and Timo Rager. "Analytical Tools to Characterize Solid Forms." In Polymorphism in the Pharmaceutical Industry. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527697847.ch14.

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Braga, Dario, Fabrizia Grepioni, Lucia Maini, and Marco Polito. "Crystal Polymorphism and Multiple Crystal Forms." In Molecular Networks. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-01367-6_7.

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Braga, Dario, Fabrizia Grepioni, Lucia Maini, and Marco Polito. "Crystal Polymorphism and Multiple Crystal Forms." In Molecular Networks. Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/430_2008_7.

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Hilfiker, Rolf, Fritz Blatter, Martin Szelagiewicz, and Markus von Raumer. "Approaches to Solid-Form Screening." In Polymorphism in the Pharmaceutical Industry. Wiley-VCH Verlag GmbH & Co. KGaA, 2018. http://dx.doi.org/10.1002/9783527697847.ch8.

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Kwokal, Ana. "Preparation, Stabilisation and Advantages of Metastable Polymorphs." In Engineering Crystallography: From Molecule to Crystal to Functional Form. Springer Netherlands, 2017. http://dx.doi.org/10.1007/978-94-024-1117-1_14.

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Das, Ankush, Henry DeYoung, Andreia Mordido, and Frank Pfenning. "Nested Session Types." In Programming Languages and Systems. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-72019-3_7.

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AbstractSession types statically describe communication protocols between concurrent message-passing processes. Unfortunately, parametric polymorphism even in its restricted prenex form is not fully understood in the context of session types. In this paper, we present the metatheory of session types extended with prenex polymorphism and, as a result, nested recursive datatypes. Remarkably, we prove that type equality is decidable by exhibiting a reduction to trace equivalence of deterministic first-order grammars. Recognizing the high theoretical complexity of the latter, we also propose a novel type equality algorithm and prove its soundness. We observe that the algorithm is surprisingly efficient and, despite its incompleteness, sufficient for all our examples. We have implemented our ideas by extending the Rast programming language with nested session types. We conclude with several examples illustrating the expressivity of our enhanced type system.
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Massoulié, J. "Polymorphism of Cholinesterase: Possible Insertion of the Various Molecular Forms in Cellular Structures." In Advances in Behavioral Biology. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5194-8_71.

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Conference papers on the topic "Polymorphic Forms"

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Herrera, Maria Lidia, Karina Dafne Martinez, Maria Ramos, Roberto Candal, Victor Alonso Garcia Londoño, and Virginia Borroni. "Effects of processing conditions and emulsifiers addition of crystallization kinetics and polymorphism of cupuassu fat and its fractions." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/dcui3885.

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A- A+ The effects of processing conditions and addition of the sucrose esters S-170 and P-170 on crystallization kinetics and polymorphism of cupuassu fat and its fractions obtained at 29, 26, and 24 °C were study by polarized light microscopy, differential scanning calorimetry, and in situ small-angle (SAXS) and wide angle (WAXS) X-ray scattering using synchrotron light. Polymorphic transitions were followed in real time tempering samples with a thermal cycle or crystallizing them isothermally at different cooling rates. Cupuassu fat and stearin fractions obtained at 26 and 24°C crystallized
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Zemlyanukhina, O. A., та E. N. Vasilchenko. "Comparative investigаtion of the physiological and biochemical properties of Beta vulgaris L. haploid lines". У CURRENT STATE, PROBLEMS AND PROSPECTS OF THE DEVELOPMENT OF AGRARIAN SCIENCE. Federal State Budget Scientific Institution “Research Institute of Agriculture of Crimea”, 2020. http://dx.doi.org/10.33952/2542-0720-2020-5-9-10-91.

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The aim of the work was to study the isoenzyme spectra of several lines of haploid regenerants of sugar beet in comparison with the parent forms in order to identify the most interesting ones for further selection. The donor material was the MS-form (malesterile form), haploid lines derived from it, as well as the fertile donor and its haploid lines.It was shown that the spectra of two enzymes − isocitrate dehydrogenase and malic enzyme are polymorphic, and the enzyme 6-phosphogluconate dehydrogenase is monomorphic and cannot be used in further selection.
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Wilhelm, S., and A. Henschen. "ON THE IDENTIFICATION OF POLYMORPHIC SITES IN HUMAN FIBRINOGEN PEPTIDE CHAINS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643327.

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Human fibrinogen has repeatedly been shown to occur in a great number of different molecular forms. Some types of heterogeneity are evident already from variations in solubility properties and in ion-exchange-chromatographic as well as gel-electrophoretic behaviour of the total molecule and of its peptide chain components. The reason for these variations are partly known.Thus, degradation of the C-terminal parts and phosphorylation of two serine residues gives rise to heterogeneity in the Aα-chain. Differences in the sialylation of the carbohydrate side chain causes heterogeneity both in the B
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Kazanceva, S. R., L. Sh Nazarova, V. A. Malievskiy, and T. V. Viktorova. "STUDY OF ASSOCIATIONS OF THE NFKB1-94I/D POLYMORPHOUS LOCUS IN THE GROUP OF PATIENTS WITH RF-NEGATIVE FORM OF JUVENILE ARTHRITIS WITH THE EFFECTIVENESS OF METOREXATE THERAPY." In I International Congress “The Latest Achievements of Medicine, Healthcare, and Health-Saving Technologies”. Kemerovo State University, 2023. http://dx.doi.org/10.21603/-i-ic-45.

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The aim of the study was to analyze the relationship of the polymorphic locus of the immune response mediator gene NFKB1 rs28362491 with the effectiveness of methotrexate therapy in a group of patients with RF-negative polyarticular form of juvenile arthritis (SA). The study involved 67 patients with a diagnosis of RF-negative polyarticular UA living in the Republic of Bashkortostan. Genotyping of all patients by polymorphic locus NFkB1 rs28362491 was carried out using polymerase chain reaction (PCR) in real time.&#x0D; The study of the polymorphic locus NFKB1 -94I/D in a group of patients wit
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Gerasimov, Alexander V., Liana S. Zubaidullina, Aisylu S. Safiullina, Ruslan N. Nagrimanov, Marat A. Ziganshin, and Artur E. Boldyrev. "Stabilization of metastable polymorphic form of glycine by glucose." In ACTUAL PROBLEMS OF ORGANIC CHEMISTRY AND BIOTECHNOLOGY (OCBT2020): Proceedings of the International Scientific Conference. AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0069199.

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Lassen, Soren B., and Paul Blain Levy. "Typed Normal Form Bisimulation for Parametric Polymorphism." In 2008 23rd Annual IEEE Symposium on Logic in Computer Science (LICS 2008). IEEE, 2008. http://dx.doi.org/10.1109/lics.2008.26.

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Nakanishi, Atsushi, Koichiro Akiyama, Shohei Hayashi, Hiroshi Satozono, and Kazuue Fujita. "Imaging identification of pharmaceutical material by using terahertz difference-frequency generation semiconductor source." In Conference on Lasers and Electro-Optics/Pacific Rim. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleopr.2022.p_cm3_01.

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We demonstrated imaging identification of pharmaceutical material using a compact ultra-broadband terahertz semiconductor source. We could obtain THz false-color RGB images from plural frequency information. We demonstrated the ability to distinguish the pharmaceutical materials having different crystal forms by using the THz DFG source. Polymorphism, hydrate forms, and crystallinity of pharmaceutical materials can be distinguished using this method.
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Рудакова, Анжела, Сергей Рудаков та Юрий Чесноков. "Изучение полиморфизма эстеразных изоферментов в семенах картирующей популяции яровой мягкой пшеницы". У VIIth International Scientific Conference “Genetics, Physiology and Plant Breeding”. Institute of Genetics, Physiology and Plant Protection, Republic of Moldova, 2021. http://dx.doi.org/10.53040/gppb7.2021.44.

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Using electrophoresis, in 114 recombinant hybrid lines of the mapping population of spring bread wheat and in 2 parental forms, 7 esterase isoenzymes were found: A1-A7 (Mr 93-138 kDa). According to their esterase composition, all samples were subdivided into 17 zymotypes. Isoforms A4 and A6 are pre-sent in all zymotypes, i.e. are monomorphic. The other 5 isozymes provide a high level of polymorphism in the population. The majority of genotypes belong to the zymotype Gr. 1 (27%), which includes 6 isoforms. Among them there are isoforms A1 and A7, characteristic only for each of the parent forms
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Davi, Caio, André Pastor, Thiego Oliveira, et al. "Computational Intelligence applied to Human Genome Data for the Dengue Severity Prognosis." In XI Simpósio Brasileiro de Bioinformática. Sociedade Brasileira de Computação - SBC, 2019. http://dx.doi.org/10.5753/bsb_estendido.2018.8800.

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Dengue has become one of the most important worldwide arthropodborne diseases around the world. Here, one hundred and two Brazilian dengue virus (DENV) III patients and controls were genotyped for 322 innate immunity gene loci. All biological data (including age, sex and genome background) were analyzed using Machine Learning techniques to discriminate tendency to severe dengue phenotype development. Our current approach produces median values for accuracy greater than 86%, with sensitivity and specificity over 98% and 51%, respectively. Genome data information from 13 key immune polymorphic S
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Tekin, Berna, and Halil Güler. "Hydrothermal synthesis and structural investigation of a new polymorph form of NdBO[sub 3]." In 2ND INTERNATIONAL ADVANCES IN APPLIED PHYSICS AND MATERIALS SCIENCE CONGRESS. AIP, 2012. http://dx.doi.org/10.1063/1.4751627.

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Reports on the topic "Polymorphic Forms"

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Sadka, Avi, Mikeal L. Roose, and Yair Erner. Molecular Genetic Analysis of Citric Acid Accumulation in Citrus Fruit. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7573071.bard.

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The acid content of the juice sac cells is a major determinant of maturity and fruit quality in citrus. Many citrus varieties accumulate acid in concentrations that exceed market desires, reducing grower income and consumer satisfaction. Pulp acidity is thought to be dependent on two mechanisms: the accumulation of citric acid in the vacuoles of the juice sac cells, and acidification of the vacuole. The major aim of the project was to direct effort toward understanding the mechanism of citric acid accumulation in the fruit. The following objectives were suggested: Measure the activity of enzym
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Kistler, Harold Corby, Talma Katan, and Dani Zamir. Molecular Karyotypes of Pathogeic Strains of Fusarium oxysporum. United States Department of Agriculture, 1995. http://dx.doi.org/10.32747/1995.7604927.bard.

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Genetic diversity of pathogenic strains of the fungus Fusarium oxysporum was determied by analysis of electrophoretic karyotype, as well as by DNA variation detected by Restriction Fragment Length Polymorphisms (RFLPs) and Random Amplified Polymorphic DNAs (RAPDs). The electrophoretic karyotypes for 130 isolates of the fungus pathogenic to tomato, melon, and banana were analyzed. Electrophoretic karyotype variation, reflected in differences in apparent chromosome number and genome size, was observed even among isolates from the same host and sub specific category. Sub specific categories studi
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Lafrancois, Toben, Mark Hove, and Jay Glase. Zebra mussel (Dreissena polymorpha) distribution in Apostle Islands National Lakeshore: SCUBA-based search and removal efforts: 2019–2020. National Park Service, 2022. http://dx.doi.org/10.36967/nrr-2293376.

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Invasive zebra mussels (Dreissena polymorpha) were first observed in situ at Apostle Islands National Lakeshore (APIS) in 2015. This report builds on 2018 SCUBA surveys and Environmental Protection Agency (EPA) veliger sampling to: 1) determine whether shoals on APIS borders act as sentinel sites to corroborate veliger drift hypotheses about invasion pathways, 2) evaluate ongoing hand-removal of zebra mussels from easily identified structures, and 3) continue efforts to assess native unionid mussel populations, particularly where zebra mussels are also present. Standard catch per unit effort s
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Gelb, Jr., Jack, Yoram Weisman, Brian Ladman, and Rosie Meir. Identification of Avian Infectious Brochitis Virus Variant Serotypes and Subtypes by PCR Product Cycle Sequencing for the Rational Selection of Effective Vaccines. United States Department of Agriculture, 2003. http://dx.doi.org/10.32747/2003.7586470.bard.

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Objectives 1. Determine the serotypic identities of 40 recent IBV isolates from commercial chickens raised in the USA and Israel. 2. Sequence all IBV field isolates using PCR product cycle sequencing and analyze their S 1 sequence to detennine their homology to other strains in the Genbank and EMBL databases. 3. Select vaccinal strains with the highest S 1 sequence homology to the field isolates and perform challenge of immunity studies in chickens in laboratory trials to detennine level of protection afforded by the vaccines. Background Infectious bronchitis (IB) is a common, economically imp
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Adill, Anders. Ekologiska trender och prognoser i recipientområdet för Forsmarks kärnkraftverk. Institutionen för akvatiska resurser, Sveriges lantbruksuniversitet, 2023. http://dx.doi.org/10.54612/a.570suuv8lh.

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Forsmarks kärnkraftverk är en av Sveriges största elproducenter och utgörs av tre stycken kokvattenreaktorer. Vid elproduktionen i kärnkraftverket krävs enorma mängder havsvatten för kylning av processerna i reaktorerna. Kylvattnet tas in till kraftverket från Öregrundsgrepen via en kanal från Asphällafjärden. Brackvattnet innehåller levande organismer i form av bland annat alger, vattenvegetation, djurplankton och fisk. De största organismerna, bland annat vegetation och fisk, avskiljs från vattnet via stora bandsilar som sitter i kylvattenintaget till kraftverket. Periodvis kan mängden rensm
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