Log in

Relevant bibliographies by topics / Polymorphism of the gene eNOS C786T / Journal articles

To see the other types of publications on this topic, follow the link: Polymorphism of the gene eNOS C786T.

Journal articles on the topic 'Polymorphism of the gene eNOS C786T'

Author: Grafiati

Published: 3 June 2025

Last updated: 31 July 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Polymorphism of the gene eNOS C786T.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Olesya, V. Romaschenko* Eduard A. Snegin Lyudmila R. Zakirova Elena B. Artyushkova Galina A. Batischeva Natalya A. Bystrova Vladimir Y. Provotorov. "GENE POLYMORPHISM OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN PATIENTS WITH STABLE ANGINA PECTORIS AND ITS SIGNIFICANCE IN THE MANIFESTATION OF GENOPROTECTIVE PROPERTIES OF MELDONIUM." Indo American Journal of Pharmaceutical Sciences 04, no. 10 (2017): 3786–91. https://doi.org/10.5281/zenodo.1020020.

Full text

Abstract:

Introduction: Personalized pharmacotherapy of stable angina pectoris implies an in-depth study of the pharmacogenetic factor when prescribing the recommended drugs in order to increase the effectiveness and safety of their use. The work is devoted to the development of individual approaches to the appointment of meldonium in the complex pharmacotherapy of angina pectoris as a cardiac cytoprotector with endothelioprotective properties, depending on gene polymorphism of endothelial nitric oxide synthase. Research tasks: To study the polymorphism of the endothelial nitric oxide synthase gene eNOS

APA, Harvard, Vancouver, ISO, and other styles

2

Troitskaya, N. I., K. G. Shapovalov, and V. A. Mudrov. "Molecular genetic polymorphisms C786T of the eNOS gene and LYS198ASN of the END1 gene in diabetic foot syndrome." Translational Medicine 9, no. 4 (2022): 13–19. http://dx.doi.org/10.18705/2311-4495-2022-9-4-13-19.

Full text

Abstract:

Background. Diabetic foot syndrome is one of the complications of diabetes mellitus, which could result inthe development of purulent-necrotic lesions of soft tissues or amputation. Nitric oxide and endothelin-1 plays key role in endothelium dysfunction, thus contributing to the pathogenesis. Objective. To evaluate the frequency of genotypes of the C786T polymorphism of the eNOS gene and the LYS198ASN polymorphism of the END1 gene in a group of patients with diabetic foot syndrome and a group of healthy donors living in the Trans-Baikal Territory. Design and methods. In 100 healthy individuals

APA, Harvard, Vancouver, ISO, and other styles

3

Троицкая, Н. И., К. Г. Шаповалов, and В. А. Мудров. "Endothelial fluctuation amplitude of microcirculation in carriers of different polymorphic markers C786T of the eNOS gene and Lys198Asn of the END1 gene with diabetic foot syndrome." Nauchno-prakticheskii zhurnal «Patogenez», no. 2 (May 31, 2022): 38–44. http://dx.doi.org/10.25557/2310-0435.2022.02.38-44.

Full text

Abstract:

Цель работы: изучить амплитуду эндотелиального диапазона колебаний микрокровотока при развитии синдрома диабетической стопы у носителей разных полиморфных маркеров C786T гена eNOS и Lys198Asn гена END1. Материалы и методы: В исследовании приняли участие 198 пациентов с неосложнённым сахарным диабетом и 199 пациентов с синдромом диабетической стопы, у которых оценили распределение генотипов полиморфных маркеров C786T гена eNOS и Lys198Asn гена END1 методом полимеразной цепной реакции. У 30 человек в каждой группе, сопоставимых по распределению полиморфизмов изучаемых генов, исследовали состояни

APA, Harvard, Vancouver, ISO, and other styles

4

ZAKHARYAN, ELENA A., та OLGA YU GRITSKEVICH. "IMPACT OF THE SINGLE-NUCLEOTIDE POLYMORPHISM OF GENES IL1β, EDN1, AND NOS3 GENES ON THE INDIVIDUAL GENETIC PROFILE OF PATIENTS WITH CORONARY HEART DISEASE IN THE REPUBLIC OF CRIMEA". Bulletin of Contemporary Clinical Medicine 16, № 6 (2023): 31–36. http://dx.doi.org/10.20969/vskm.2023.16(6).31-36.

Full text

Abstract:

Abstracts. Introduction. Coronary heart disease prevalence rate grows, which determines the importance of researchers’ inquiries aiming to improve the prevention, diagnosis, and treatment of this pathology. Aim. This study was aimed at identifying the associations of polymorphisms of genes interleukin 1-beta, endothelin-1, and endothelial nitric oxide synthase in patients with coronary heart disease. Materials and Methods. We studied polymorphic markers of endothelin-1 (rs5370), endothelial nitric oxide synthase (rs2070244), and interleukin 1-beta genes (rs1143634 and rs16944) in patients with

APA, Harvard, Vancouver, ISO, and other styles

5

Krotkov, K. O. "GENE POLYMORPHISMS AND CLINICAL, DEMOGRAPHIC, ANTHROPOLOGICAL DATA IN PATIENTS WITH ISCHEMIC HEART DISEASE WHO UNDERWENT CORONARY ARTERY BYPASS GRAFTING UNDER ARTIFICIAL CIRCULATION." Journal of the Grodno State Medical University 22, no. 6 (2025): 544–47. https://doi.org/10.25298/2221-8785-2024-22-6-544-547.

Full text

Abstract:

Objective. To identify the relationship between polymorphisms of the angiotensin type 1 receptor gene (AGT2R1 A1166C) (rs 5186), endothelin-1 gene (LYS198ASN) (rs 5370), endothelial nitric oxide synthase gene NOS3 (C786T) (rs 2070744) and clinical, demographic, anthropological data in patients with coronary heart disease who underwent coronary artery bypass grafting under artificial circulation. Material and methods. All patients (123 people) underwent intraoperative venous blood sampling from a central venous catheter. Then, using the polymerase chain reaction method, there was performed an i

APA, Harvard, Vancouver, ISO, and other styles

6

Krotkov, K. O. "IMPACT OF EXTRACORPOREAL AUTOHEMOMAGNETOTHERAPY ON THE ACID-BASE STATE OF ARTERIAL BLOOD IN THE INTRAOPERATIVE PERIOD DURING MYOCARDIAL REVASCULARIZATION UNDER ARTIFICIAL CIRCULATION." Journal of the Grodno State Medical University 22, no. 5 (2024): 465–69. http://dx.doi.org/10.25298/2221-8785-2024-22-5-465-469.

Full text

Abstract:

Background. To evaluate changes in acid-base balance in patients with coronary heart disease in the intraoperative period during coronary artery bypass grafting under artificial circulation using extracorporeal autohemomagnetotherapy (EAHMT). To consider the presence of a negative effect of this technique on acid-base balance. To study the possible relationship between the polymorphism of the angiotensin-1 receptor gene (AGTR1 A1166C), endothelin-1 (EDN1 Lys 198 Asn), endothelial nitric oxide synthase (NOS3 C786T) and changes in the studied parameters of acid-base balance. Material and methods

APA, Harvard, Vancouver, ISO, and other styles

7

Колоцей, Л. В. "Association of Endothelial NO-Syntase Gene C786T Polymorphism with the Development of Drug-Induced Long QT Interval Syndrome Caused by Class III Antiarrhythmic Drugs." Рецепт, no. 4 (September 13, 2022): 542–55. http://dx.doi.org/10.34883/pi.2022.25.4.020.

Full text

Abstract:

Цель. Установить взаимосвязь полиморфизма С786T гена эндотелиальной синтазы оксида азота (NOS3) с электрокардиографическими показателями реполяризации желудочков, а также риском развития лекарственно-индуцированного синдрома удлиненного интервала QT (СУИ QT) и неустойчивой полиморфной желудочковой тахикардии (ЖТ) на фоне приема антиаритмических препаратов III класса.Материалы и методы. В исследование включено 92 пациента: из них 75 (основная группа) – с ишемической болезнью сердца (ИБС) и/или артериальной гипертензией (АГ) и нарушениями ритма сердца, принимавших антиаритмические препараты III

APA, Harvard, Vancouver, ISO, and other styles

8

Abolhalaj, Milad, Mahsa M. Amoli, and Parvin Amiri. "eNOS Gene Variant in Patients with Coronary Artery Disease." Journal of Biomarkers 2013 (December 4, 2013): 1–6. http://dx.doi.org/10.1155/2013/403783.

Full text

Abstract:

Subject & Aim. Endothelial nitric oxide synthase (eNOS) is one of the most important candidate genes in CAD. A functional polymorphism within eNOS gene is a 27 bp VNTR on its intron 4 which has been shown to be associated with various diseases. In this study we investigated eNOS VNTR polymorphism in addition to eNOS gene expression profile in patients with CAD. Material and Methods. The study comprised patients with angiographically confirmed CAD (CAD+) and individuals with normal coronary as CAD−. eNOS VNTR polymorphism frequencies were determined in both groups. In addition eNOS gene exp

APA, Harvard, Vancouver, ISO, and other styles

9

Nesen, A. O., P. S. Semenovykh, K. O. Savicheva, V. Y. ,. Galchinska, and V. L. Shkapo. "Features of prooxidant/antioxidant balance disorders in patients with diabetic nephropathy — carriers of different genotypes of G894T polymorphism of eNOS gene." Ukrainian Therapeutical Journal, no. 3 (October 7, 2024): 5–11. http://dx.doi.org/10.30978/utj2024-3-5.

Full text

Abstract:

Objective — to determinate the state of prooxidant‑antioxidant balance in patients with type 2 diabetes mellitus with nephropathy — carriers of different genotypes of G894T (rs 1799983) polymorphism of eNOS gene. Materials and methods. 126 patients with diabetic nephropathy (DN) were examined. The control group included 20 healthy individuals. Patients with type 2 diabetes mellitus (DM) were divided into two groups depending on the eNOS rs 1799983 gene polymorphism: group I — patients with DN and G/G genotype eNOS G894T gene (n=80); group II — patients with DN and G/T and T/T genotypes eNOS G8

APA, Harvard, Vancouver, ISO, and other styles

10

Dosenko, Victor E., Vyacheslav Y. Zagoriy, Nikolay V. Haytovich, Olga A. Gordok, and Alexey A. Moibenko. "Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations." Acta Biochimica Polonica 53, no. 2 (2006): 299–302. http://dx.doi.org/10.18388/abp.2006_3342.

Full text

Abstract:

Investigation of the mechanisms of phenotypic realization of allelic polymorphism of the eNOS gene has shown that the level of eNOS mRNA and activity of this enzyme in platelets depends from genotype. We identified a T(-786)-->C polymorphism in the promoter region, a variable number of tandem repeats (4a/4b) in intron 4 and the G(894)-->T polymorphism in exon 7 of the eNOS gene in isolated human platelets. We measured eNOS mRNA in isolated platelets by reverse transcription-PCR and eNOS enzyme activity by fluorimetric detection system FCANOS-1 using diaminofluorescein diacetate (DAF-2A).

APA, Harvard, Vancouver, ISO, and other styles

11

Nishank, Sudhansu Sekhar. "ENDOTHELIAL NITRIC OXIDE SYNTHASE (ENOS) GENE POLYMORPHISM IS ASSOCIATED WITH AGE ONSET OF MENARCHE IN SICKLE CELL DISEASE FEMALES OF INDIA." Mediterranean Journal of Hematology and Infectious Diseases 5, no. 1 (2013): e2013036. http://dx.doi.org/10.4084/mjhid.2013.036.

Full text

Abstract:

ABSTRACT Background and Objective : Females with sickle cell disease (SCD) often show late onset of menarche. In transgenic sickle cell mouse, deficiency of gene encoding endothelial nitric oxide synthase (eNOS) has been reported to be associated with late onset of menarche. Thus to explore the possible association of eNOS gene polymorphism with age of onset of menarche in SCD females, 3 important eNOS gene polymorphism- eNOS 4a/b, eNOS 894G>T and eNOS-786 T>C and plasma nitrite levels were tested among three groups of females- SCD late menarche, SCD early menarche and control females. M

APA, Harvard, Vancouver, ISO, and other styles

12

Ceylan, Gozde, Nur Gumus, Sule Seckin, Oner Sanli, Selcuk Erdem, and Canan Kucukgergin. "Genetic variants of endothelial nitric oxide synthase (eNOS 4a/b) and susceptibility to renal cell carcinoma in a Turkish population." Genetika 55, no. 2 (2023): 719–28. http://dx.doi.org/10.2298/gensr2302719c.

Full text

Abstract:

Nitric oxide (NO), plays a significant part in biological processes. Endothelial nitric oxide synthase (eNOS), the enzyme that catalyzes the generation of NO in endothelium, contains genetic polymorphisms that have been linked to an increased risk of developing cancer. The purpose of this investigation was to ascertain whether there is any connection between renal cell carcinom (RCC) and the eNOS 4a/b gene polymorphism. This study included 94 patients (mean age:54.2?10.5 years) diagnosed with histopathologically confirmed RCC and 188 healthy controls (mean age:56.7?11.1 years). eNOS 4a/b gene

APA, Harvard, Vancouver, ISO, and other styles

13

Milutinović, Aleksandra, and H. Hruškovičova. "The eNOS Gene Polymorphism Does Not Have a Major Impact on Lipid Parameters and Premature Coronary Artery Disease in Slovene Men (Caucasians)." Folia Biologica 51, no. 2 (2005): 47–49. https://doi.org/10.14712/fb2005051020047.

Full text

Abstract:

eNOS affects the NO level in the blood vessel wall, and therefore eNOS might be considered as a candidate gene for CAD. In this cross-sectional case-control association study we tested the hypothesis whether the eNOS 4a/b gene polymorphism is a genetic marker for premature CAD in Slovene men. The eNOS 4a/b gene polymorphism was tested in 403 Slovene men: 215 cases with premature CAD and 188 subjects with no history of CAD. The frequency of 4a/b genotypes did not differ between patients and controls: in CAD patients the frequencies of the 4aa, 4ab, or 4bb genotype were 5.0%, 27.9%, or 67.1%, re

APA, Harvard, Vancouver, ISO, and other styles

14

Nesen, A. O., P. S. Semenovykh, K. O. Savicheva, and V. Y. Galchinska. "The relationship between polymorphic variants of the endothelial NO-synthase gene and the course of diabetic nephropathy in patients with type 2 diabetes mellitus." Ukrainian Therapeutical Journal, no. 4 (December 23, 2023): 33–39. http://dx.doi.org/10.30978/utj2023-4-33.

Full text

Abstract:

Objective — to identify a possible association between the endothelial nitric oxide synthase (eNOS) gene G894T (rs1799983) polymorphism and the markers of renal function and glucose metabolism in patients with type 2 diabetes mellitus (DM2) with diabetic nephropathy (DN). Materials and methods. Examinations 126 patients with diabetic nephropathy (DN). The control group included 20 healthy individuals. Patients with DM2 were divided into two groups depending on the eNOS rs1799983 gene polymorphism: group I — patients with DN and G/G genotype eNOS G894T gene (n=80); group II — patients wit

APA, Harvard, Vancouver, ISO, and other styles

15

Cherniavska, Yuliia I., Valeriy I. Pokhylko, Tetiana K. Znamenska, Olga V. Vorobiova, and Nataliia I. Hasiuk. "EFFECT OF ENOS GENE POLYMORPHISM ON THE COURSE OF EARLY ONSET BACTERIAL INFECTIONS IN PREMATURE INFANTS." Wiadomości Lekarskie 73, no. 6 (2020): 1237–40. http://dx.doi.org/10.36740/wlek202006130.

Full text

Abstract:

The aim of the study was to analyze the associations between 4a/4b polymorphism of the eNOS gene and impaired systemic hemodynamics in premature infants with early neonatal sepsis. Materials and methods: We conducted a prospective cohort study, which included 120 premature babies with early neonatal sepsis, in 57 children the course of the disease was accompanied by arterial hypotension (AH) and in 61 children – not. In children of both groups, genotyping was performed to determine 4a/4b polymorphism of the eNOS gene. Results: It was shown that the heart rate, blood pressure, hourly diuresis,

APA, Harvard, Vancouver, ISO, and other styles

16

Tavana, Zohreh, Azadeh Khalili, Golnaz Namazi, et al. "Prevalence of common polymorphisms of AT-rich interaction domain 1A and endothelial nitric oxide synthase in patients with endometriosis compared to control group." Journal of Endometriosis and Pelvic Pain Disorders 10, no. 1 (2018): 26–31. http://dx.doi.org/10.1177/2284026518764352.

Full text

Abstract:

Introduction: Endometriosis is a common gynecologic disorder defined as ectopic presence of endometrial tissue in extrauterine sites. Endometriosis is associated with infertility and risk of malignancy. Identification of genetic factors responsible for development and malignant transformation of endometriosis can improve therapeutic approaches. In this study, we investigated the association of AT-rich interaction domain 1A ( ARID1A) and endothelial nitric oxide synthase ( eNOS) polymorphisms with endometriosis and staging of the disease. Methods: A total of 100 women with laparoscopy-confirmed

APA, Harvard, Vancouver, ISO, and other styles

17

Duve, K. V. "Prevalence of 4a/4b polymorphic variants of the eNOS gene introne in patients with different types of encephalopathies." Ukrainian Biochemical Journal 95, no. 5 (2023): 76–84. http://dx.doi.org/10.15407/ubj95.05.076.

Full text

Abstract:

Questions related to the disruption of vasoregulatory processes as essential factor in neurological pathology require further study. The leading role in the vasoregulatory mechanisms is played by endothelial NO synthase which gene has 15 allelic variants. Recent data indicated a probable association between eNOS gene polymorphism and cerebrovascular diseases. The aim of the present work was to study the prevalence of the 4a/4b introne polymorphism of the eNOS gene in patients with various types of encephalopathies and to evaluate the influence of a particular genotype of the studied gene on th

APA, Harvard, Vancouver, ISO, and other styles

18

Ziaei, Seyed Amir Mohsen, Mohammad Samzadeh, Seyed Hamid Jamaldini, Mahdi Afshari, Ali Akbar Haghdoost, and Mandana Hasanzad. "Endothelial Nitric Oxide Synthase Glu298Asp Polymorphism as a Risk Factor for Prostate Cancer." International Journal of Biological Markers 28, no. 1 (2013): 43–48. http://dx.doi.org/10.5301/jbm.2012.9585.

Full text

Abstract:

Background The endothelial form of nitric oxide synthases (eNOS) seems to have an important role in vascular development, maintenance of the vascular tone and tumor growth in human prostate cancer (PC). The purpose of this study was to investigate the association between grade and stage of disease, age of diagnosis, vascular or perineural invasion, pre-diagnostic plasma prostate-specific antigen (PSA) levels, prostate cancer risk and Glu298Asp polymorphism of the eNOS gene. Methods Ninety-five prostate cancer patients and 111 benign prostate hyperplasia subjects were included. The Glu298Asp po

APA, Harvard, Vancouver, ISO, and other styles

19

Li, Hui, Guiqin Shu, and Huihui Gao. "Epithelial nitric oxide synthases (eNOS) 894 G < T polymorphism and diabetic nephropathy susceptibility: A meta-analysis." Pteridines 33, no. 1 (2022): 49–57. http://dx.doi.org/10.1515/pteridines-2022-0042.

Full text

Abstract:

Abstract Objective To investigate the epithelial nitric oxide synthases (eNOS) 894 G < T polymorphism and diabetic nephropathy (DN) susceptibility by pooling the open published data. Methods Studies relevant to eNOS 894 G < T polymorphism and DN susceptibility published in PubMed, EMBASE, Medline, CNKI, and Wanfang databases were systematically screened by using the text words of endothelial nitric oxide synthase, eNOS, NOS-3, G894T, rs179983, polymorphism, diabetic nephropathy, and DN. The correlation between eNOS 894 G < T polymorphism and DN susceptibility was demonstrated by odds

APA, Harvard, Vancouver, ISO, and other styles

20

Jaishankar, Thirunavukkarasu, Meera Shivasekar, and V. M. Vinodhini. "eNOS T786C (rs2070744) Gene Polymorphism and Its Underlying Mechanism Associated with Coronary Heart Disease." Journal of Hunan University Natural Sciences 49, no. 4 (2022): 164–71. http://dx.doi.org/10.55463/issn.1674-2974.49.4.16.

Full text

Abstract:

The study aims to examine plasma nitric oxide concentration and its relationship to T-786C gene polymorphism levels in the development of coronary heart disease in young people. Reduced nitric oxide (NO) bioavailability and endothelial nitric oxide synthase (eNOS) T786C gene polymorphism have been identified as risk factors for the development of coronary heart disease. This cross-sectional study was conducted in SRM Medical College Hospital and Research Centre on 200 angiographically proven CHD subjects attending the Department of Cardiology and medicine and 100 controls from MHC in the age g

APA, Harvard, Vancouver, ISO, and other styles

21

Chernykh, D. V., A. V. Shevchenko, V. F. Prokofev, et al. "On the issue of the presence of VEGF and eNOS gene polymorphisms in non-proliferative diabetic retinopathy." Modern technologies in ophtalmology, no. 1 (March 25, 2022): 150–53. http://dx.doi.org/10.25276/2312-4911-2022-1-150-153.

Full text

Abstract:

Purpose. To analyze the polymorphism of the regulatory regions VEGFand eNOS genes polymorphism and their combinations in patients with type 2 diabetes with and without non-proliferative DR. Material and methods. The study included 200 patients with type 2 diabetes 111 patients with type 2 diabetes without signs of DR and 89 patients with non-proliferative DR. The polymorphism of the regulatory regions of VEGF(rs699947 and rs3025039) and eNOS(rs2070744) genes was studied using restriction fragment length polymorphism analysis and Real-Time PCR by TaqMan probes. Statistical: used by StatSoft Sta

APA, Harvard, Vancouver, ISO, and other styles

22

Chernykh, D. V., A. V. Shevchenko, V. F. Prokofev, et al. "On the issue of the presence of VEGF and eNOS gene polymorphisms in non-proliferative diabetic retinopathy." Modern technologies in ophtalmology, no. 1 (March 25, 2022): 150–53. http://dx.doi.org/10.25276/2312-4911-2022-1-150-153.

Full text

Abstract:

Purpose. To analyze the polymorphism of the regulatory regions VEGFand eNOS genes polymorphism and their combinations in patients with type 2 diabetes with and without non-proliferative DR. Material and methods. The study included 200 patients with type 2 diabetes 111 patients with type 2 diabetes without signs of DR and 89 patients with non-proliferative DR. The polymorphism of the regulatory regions of VEGF(rs699947 and rs3025039) and eNOS(rs2070744) genes was studied using restriction fragment length polymorphism analysis and Real-Time PCR by TaqMan probes. Statistical: used by StatSoft Sta

APA, Harvard, Vancouver, ISO, and other styles

23

Levashova, O. A., N. I. Baranova, and I. G. Zolkornyaev. "Investigation of the correlation of allele polymorphism of renin-angiotensin system genes, nitric oxide synthase and folate cycle with the severity of ischemic stroke." Kazan medical journal 99, no. 3 (2018): 404–8. http://dx.doi.org/10.17816/kmj2018-404.

Full text

Abstract:

Aim. To study the frequency of polymorphic gene variants encoding proteins of renin-angiotensin system [AGT Thr174Met (rs 4762), AGT Met235Thr (rs699), AGTR1 A1166C (rs5186)], endothelial factors [NOS3 C786T (rs2070744)], and folate cycle enzymes [MTHFR C677T (rs1801133)] in patients with various ischemic stroke severity. Methods. 98 patients with ischemic stroke verified by magnetic resonance imaging and computed tomography scan of the brain, were examined. The severity of stroke was assessed by National Institutes of Health Stroke Scale. The allelic variants of genes were typified by polymer

APA, Harvard, Vancouver, ISO, and other styles

24

R., Vasudevan, Ismail P., Jaafar N.I., et al. "Analysis of Human Bradykinin Receptor Gene and Endothelial Nitric Oxide Synthase Gene Polymorphisms in End-Stage Renal Disease Among Malaysians." Balkan Journal of Medical Genetics 17, no. 1 (2014): 37–40. http://dx.doi.org/10.2478/bjmg-2014-0023.

Full text

Abstract:

Abstract The aim of this study was to determine the association of the c.894G>T; p.Glu298Asp polymorphism and the variable number tandem repeat (VNTR) polymorphism of the endothelial nitric oxide synthase (eNOS) gene and c.181C>T polymorphism of the bradykinin type 2 receptor gene (B2R) in Malaysian end-stage renal disease (ESRD) subjects. A total of 150 ESRD patients were recruited from the National Kidney Foundation’s (NKF)dialysis centers in Malaysia and compared with 150 normal healthy individuals. Genomic DNA was extracted from buccal cells of all the subjects. The polymerase chain

APA, Harvard, Vancouver, ISO, and other styles

25

Chernova, A. A., S. Yu Nikulina, and Yu A. Tolstokorova. "Association of eNOS (4a/4b) gene polymorphism with the development of arterial hypertension in patients with rheumatoid arthritis." Russian Medical Inquiry 4, no. 8 (2020): 471–74. http://dx.doi.org/10.32364/2587-6821-2020-4-8-471-474.

Full text

Abstract:

Aim: to study a contribution of eNOS (4a/4b) gene polymorphism in the development of arterial hypertension (AH) in patients with rheumatoid arthritis (RA).Patients and Methods: 143 patients with RA were examined, among which a group of patients without AH (n=50) and a group of patients with RA in association with AH (n=93) were selected. Healthy volunteers (n=151) were also divided into 2 groups, comparable in age and gender to the main groups. A range of clinical, laboratory, and instrumental methods were used in this study. We also conducted molecular genetics. Blood samples were taken from

APA, Harvard, Vancouver, ISO, and other styles

26

Malakoutian, Tahereh, Bahareh Madadi, and Ahmad Ebrahimi. "Evaluation of common polymorphisms of eNOS gene and ACE gene in autosomal dominant polycystic kidney disease patients and their association with hypertension and renal failure." Journal of Renal Injury Prevention 10, no. 1 (2019): e04-e04. http://dx.doi.org/10.34172/jrip.2021.04.

Full text

Abstract:

Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is the most hereditary renal disease that leads to end-stage renal disease (ESRD). Objectives: Since there is no available parameter to assess the clinical course of ADPKD and its outcome, yet, the aim of our study was evaluation of the association of common polymorphisms of eNOS and ACE genes with clinical manifestations (kidney failure and hypertension) in ADPKD. Patients and Methods: Seventy-five ADPKD patients and 100 control subjects participated in our study. Around 7.5 cc of whole blood was taken from each participant an

APA, Harvard, Vancouver, ISO, and other styles

27

Lidya, Metri, Elvia Metti, Murniati Muchtar, Yolanda Syahdia, and Rani Intan Permata. "ANALISIS POLIMORFISME GEN (eNOS) DAN ESTRADIOL PADA PENDERITA ENDOMETRIOSIS." Media Penelitian dan Pengembangan Kesehatan 33, no. 4 (2023): 238–44. http://dx.doi.org/10.34011/jmp2k.v33i4.1885.

Full text

Abstract:

Endometriosis is characterized by inflammation and is an estrogen-dependent disease that affects 6-10% of women during their reproductive years and up to 50% of women who received fertility treatment. The purpose of this study was to determine the relationship between endothelial nitric oxide synthase gene polymorphisms (eNOS) and levels of the hormone estradiol. This type of research is an analytic observational study with a comparative cross-sectional study design where the dependent and independent variables are obtained simultaneously. The research was conducted in hospitals types B and C

APA, Harvard, Vancouver, ISO, and other styles

28

Senturk, Nilgun, Nurten Kara, Fatma Aydin, et al. "Association of eNOS gene polymorphism (Glu298Asp) with psoriasis." Journal of Dermatological Science 44, no. 1 (2006): 52–55. http://dx.doi.org/10.1016/j.jdermsci.2006.05.011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Dib, Azza, Hanan Hijazi, Hana Hammoud, and Yasmeen Obeid. "Investigation of the Effect of Two Major eNOS Polymorphisms (4a/b and T786C) on Coronary Artery Disease in North Lebanon." International Research Journal of Multidisciplinary Scope 06, no. 01 (2025): 641–51. https://doi.org/10.47857/irjms.2025.v06i01.02762.

Full text

Abstract:

Endothelial nitric oxide synthase is a crucial gene associated with coronary artery disease, owing to the important functions of nitric oxide in vessel protection and vasodilation. Three “Single Nucleotide Polymorphisms” were found to be significantly associated with CAD: ‘the 4a/b polymorphism in intron 4’, ‘G894T (GLU298ASP) in exon 7’, and ‘the T786C replacement in the flanking region’. This study aimed to explore the relationship between the '4a/b polymorphism of the eNOS gene', the 'T786C polymorphism of the eNOS gene', and 'the combined effect of both 4a/b and T786C' with the risk of CAD

APA, Harvard, Vancouver, ISO, and other styles

30

Khurana, Vini G., Youvraj R. Sohni, Wells I. Mangrum, et al. "Endothelial Nitric Oxide Synthase Gene Polymorphisms Predict Susceptibility to Aneurysmal Subarachnoid Hemorrhage and Cerebral Vasospasm." Journal of Cerebral Blood Flow & Metabolism 24, no. 3 (2004): 291–97. http://dx.doi.org/10.1097/01.wcb.0000110540.96047.c7.

Full text

Abstract:

Rupture of an intracranial aneurysm (subarachnoid hemorrhage) is a potentially devastating condition frequently complicated by delayed cerebral ischemia from sustained contraction of intracranial arteries (cerebral vasospasm). There is mounting evidence linking the formation of intracranial aneurysms and the pathogenesis of post-subarachnoid hemorrhage vasospasm to aberrant bioavailability and action of the vasodilator molecule nitric oxide generated by isoforms of nitric oxide synthase. In humans, the gene encoding the endothelial isoform of nitric oxide synthase (eNOS) is known to be polymor

APA, Harvard, Vancouver, ISO, and other styles

31

Pidruchna, Svitlana, Uliana Zakharchuk, Olga Svan, Bohdan Zablotskyi, and Oleksandr Tokarskyy. "Adipokine levels and T786C polymorphism of eNOS gene promoter correlation in patients with arterial hypertension." Endocrine Regulations 59, no. 1 (2025): 17–23. https://doi.org/10.2478/enr-2025-0003.

Full text

Abstract:

Abstract Objective. Genetic factors contribute to the development of metabolic syndrome and subsequent arterial hypertension (AH). The study of the T786C polymorphism of the endothelial nitric oxide synthase (eNOS) gene in arterial hypertension is important as its correlation with adipokine imbalance is a novelty area to find associations between hypertension development, obesity, and heredity. The purpose of the current study was to investigate serum adipokines levels, depending on the T786C polymorphism of the eNOS in patients with arterial hypertension. Methods. We examined 86 patients with

APA, Harvard, Vancouver, ISO, and other styles

32

Piccoli, JCE, V. Manfredini, D. Faoro, FM Farias, LC Bodanese, and MR Bogo. "Association between endothelial nitric oxide synthase gene polymorphism (-786T>C) and interleukin-6 in acute coronary syndrome." Human & Experimental Toxicology 33, no. 4 (2013): 396–402. http://dx.doi.org/10.1177/0960327113499046.

Full text

Abstract:

Atherosclerosis is morphologically an inflammatory disease, where endothelial dysfunction plays a key role in all the stages. The nitric oxide (NO) synthase 3 ( NOS3) gene is responsible for the synthesis of endothelial NO synthase (eNOS) in humans and some genetic polymorphisms are considered “polymorphisms associated with risk” for the development of coronary artery diseases, such as acute coronary syndrome. Thus, the present study aimed to evaluate the influence of the -786T>C polymorphism of the eNOS gene on inflammatory and oxidative process. A prospective cohort study of 125 consecuti

APA, Harvard, Vancouver, ISO, and other styles

33

Zaitseva, N. V., A. A. Subbotina, and O. V. Dolgikh. "Markers of bone metabolism and polymorphism of the eNOS gene in the children's population of the Eastern Siberia region with diseases of the musculoskeletal system." YAKUT MEDICAL JOURNAL 82, no. 2 (2023): 118–21. https://doi.org/10.25789/ymj.2023.82.28.

Full text

Abstract:

At present, it seems quite relevant to study genetic predictors of all classes of diseases in children including diseases of the musculoskeletal system. The aim of this study was to examine markers of musculoskeletal diseases associated with specific indicators of bone metabolism and the G894T polymorphism of the eNOS gene in children from Eastern Siberia. Materials and methods. We examined two groups of children aged 3-7 years from Eastern Siberia. The main group was made of 69 children with diseases of the musculoskeletal system. The comparison group included 47 children without such disease

APA, Harvard, Vancouver, ISO, and other styles

34

Imamura, Akiko, Ryotaro Takahashi, Ryuichiro Murakami, et al. "The effects of endothelial nitric oxide synthase gene polymorphisms on endothelial function and metabolic risk factors in healthy subjects: the significance of plasma adiponectin levels." European Journal of Endocrinology 158, no. 2 (2008): 189–95. http://dx.doi.org/10.1530/eje-07-0632.

Full text

Abstract:

ObjectiveGenetic variants of the endothelial nitric oxide synthase (eNOS) gene, Glu298Asp and T–786C, have been reported to be associated with cardiovascular disease. Adiponectin is an adipocyte-derived plasma protein with insulin-sensitizing and vascular protective effects; its levels are typically low in metabolic syndrome. Therefore, eNOS gene polymorphisms may also be associated with specific metabolic profiles, including plasma adiponectin levels and atherogenic lipids.MethodsWe evaluated the functional significance of eNOS gene Glu298Asp and T–786C polymorphisms on endothelial function a

APA, Harvard, Vancouver, ISO, and other styles

35

Petrovič, Mojca Globočnik, Ines Cilenšek, and Daniel Petrovič. "Manganese Superoxide Dismutase Gene Polymorphism (V16A) is Associated with Diabetic Retinopathy in Slovene (Caucasians) Type 2 Diabetes Patients." Disease Markers 24, no. 1 (2008): 59–64. http://dx.doi.org/10.1155/2008/940703.

Full text

Abstract:

Substantial data indicate that oxidative stress is involved in the development of diabetic retinopathy. Two candidate genes that affect the oxidative stress are manganese mitochondrial superoxide dismutase (Mn-SOD) and endothelial nitric oxide synthase (eNOS). The aim of the present study was to examine the role of the V16A polymorphism of the Mn-SOD gene and the 4a/b polymorphism of the eNOS gene in the development of diabetic retinopathy in Caucasians with type 2 diabetes.In this cross sectional case-control study 426 unrelated Slovene subjects (Caucasians) with type 2 diabetes mellitus were

APA, Harvard, Vancouver, ISO, and other styles

36

Kerkeni, Mohsen, Faouzi Addad, Maryline Chauffert, et al. "Hyperhomocysteinemia, Endothelial Nitric Oxide Synthase Polymorphism, and Risk of Coronary Artery Disease." Clinical Chemistry 52, no. 1 (2006): 53–58. http://dx.doi.org/10.1373/clinchem.2005.057950.

Full text

Abstract:

Abstract Background: Hyperhomocysteinemia is an independent, graded risk factor for coronary artery disease (CAD). The G894T variant of endothelial nitric oxide synthase (eNOS) was postulated to be associated with hyperhomocysteinemia and could influence individual susceptibility to CAD. The aims of this study were to investigate (a) the relationship of the eNOS G894T polymorphism with the presence and the severity of CAD and (b) the possible relationship between hyperhomocysteinemia and the eNOS G894T variant for the risk of CAD severity in a Tunisian population. Methods: We used PCR with res

APA, Harvard, Vancouver, ISO, and other styles

37

Zakaria, Iskandar, Arif Faisal, Sri Sutarni, Ahmad Hamim Sadewa, and Imran Imran. "NITRIT OKSIDA DAN VOLUME EDEMA OTAK PADA STROK PERDARAHAN DALAM OTAK DENGAN POLIMORFISME G894T (Nitric Oxide and Cerebral Edema Volume in Intracerebral Hemorrhagic Stroke with G894T Polymorphism)." INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY 22, no. 1 (2018): 87. http://dx.doi.org/10.24293/ijcpml.v22i1.1229.

Full text

Abstract:

Nitric Oxide (NO) is a vasodilator that regulates vascular smooth muscle tone. Low levels of NO can cause vasoconstriction andhemodynamic disturbances. In stroke the levels of NO are increased. Endothelial nitric oxide synthase gene polymorphism (eNOS) isbelieved to reduce levels of NO in blood. NO levels decreased in stroke patients with G894T polymorphisms of eNOS gene. Mortality rateof hemorrhagic stroke are increased in case with increased peri focal edema volume. The mechanism of the increased of peri focal edemavolume completely unknown yet, suspected genetics factor. This study was cond

APA, Harvard, Vancouver, ISO, and other styles

38

Kaur, Kirandeep, Ashok Uppal, and Anupam Kaur. "An exonic G894T variant of endothelial nitric oxide synthase gene as a risk factor for ischemic stroke in North Indians." Acta Neurobiologiae Experimentalis 75, no. 4 (2015): 339–50. http://dx.doi.org/10.55782/ane-2015-2039.

Full text

Abstract:

Nitric oxide (NO) synthesized by endothelial nitric oxide synthase (eNOS) enzyme is a critical regulator of cerebrovascular homeostasis. Genetic variability of G894T and intronic 4ab polymorphism in eNOS could affect the expression and activity of eNOS enzyme, modulating NO levels in endothelium. This results in endothelial dysfunction, which can contribute to the pathogenesis of ischemic stroke. The purpose of the study was to evaluate the association of eNOS genetic polymorphisms (G894T and 4ab) with the occurrence of ischemic stroke through various genetic models. Both polymorphisms were ge

APA, Harvard, Vancouver, ISO, and other styles

39

Gluba, Anna, Maciej Banach, Jacek Rysz, Grzegorz Piotrowski, Wojciech Fendler, and Tadeusz Pietrucha. "Is Polymorphism within eNOS Gene Associated With the Late Onset of Myocardial Infarction? A Pilot Study." Angiology 60, no. 5 (2009): 588–95. http://dx.doi.org/10.1177/0003319709335031.

Full text

Abstract:

Introduction Nitric oxide (NO) produced by endothelial nitric oxide synthase (eNOS) is a potent vasodilator. Several polymorphisms in the eNOS gene have been described, some of them being linked with the increased risk of cardiovascular disease, coronary heart disease (CHD), and coronary spasm. Methods and Results We studied 3 polymorphisms within the gene of eNOS (-786T/C, G10T, and 894 G/T) in patients with their first myocardial infarction (MI) younger than 45 years and in healthy volunteers. We found the relation between the occurrence of eNOS 894G allele and the Gensini score, which descr

APA, Harvard, Vancouver, ISO, and other styles

40

Kobaidze, E. G. "Study of genes involved in angiogenesis and metabolic processes of peripheral blood lymphocytes in patients with chronic endometritis." Perm Medical Journal 38, no. 4 (2021): 25–35. http://dx.doi.org/10.17816/pmj38425-35.

Full text

Abstract:

Objective. To study the polymorphisms of the genes involved in angiogenesis and in metabolic processes, to assess the level of lymphocytes in patients with chronic endometritis and practically healthy women of reproductive period. Materials and methods. 86 patients were examined; DNA regions of the genes eNOS 1799983 (Glu298Asp), PPARA (G2528C), ApoE rs429358 (Cys130Arg), MTHFR (C677T, A1298C) were used as primers; blood lymphocytes (CD3+, CD4+, CD8+, CD19+, CD95+) were assessed. Results. Statistically significant differences in gynecological and chronic somatic pathology were obta

APA, Harvard, Vancouver, ISO, and other styles

41

Tuygun, AK, M. Keser, A. Tuygun, et al. "Effects of Endothelial Nitric Oxide Synthase, Interleukin-6 Gene Polymorphisms and Asymmetric Dimethylarginine Levels on Risk Factors and Lesion Sites in Peripheral Artery Disease." Journal of International Medical Research 37, no. 4 (2009): 1003–10. http://dx.doi.org/10.1177/147323000903700404.

Full text

Abstract:

This study investigated risk factors for atherosclerosis and their relationship with lesion sites. Patients ( n = 160) with peripheral artery disease (PAD) completed a questionnaire regarding risk factors for PAD. Endothelial nitric oxide synthase (eNOS) and interleukin (IL)-6 gene polymorphisms and asymmetric dimethylarginine (ADMA) levels were measured. Patients with coronary artery disease had significantly higher ratios of eNOS T/C and C/C genotypes, which include the C allele, than the T/T genotype. The IL-6 gene polymorphism distribution ratios for patients with over four risk factors we

APA, Harvard, Vancouver, ISO, and other styles

42

Avdic, Aldijana, Naida Lojo-Kadric, Jasmin Ramic, Lejla Pojskic, and Vesna Hadziavdic. "MOLECULAR-GENETIC TYPING OF VNTR POLYMORPHISM eNOS GENE IN HUMAN POPULATION OF TUZLA CANTON." Journal Human Research in Rehabilitation 12, no. 1 (2022): 22–26. http://dx.doi.org/10.21554/hrr.042202.

Full text

Abstract:

The aim of the paper is to present the results of the VNTR gene polymorphism genetic variants molecular typing for endothelial nitric oxide synthase (eNOS) in human population of Tuzla Canton. Based on the analysis of the distribution of eNOS gene genotypes in the total sample of respondents, the highest frequency was recorded for the (b/b) genotype, which was 73.0%. For the heterozygous (a/b) genotype of the eNOS gene, a frequency of 24.0% was determined, and a frequency of 3.0% was recorded for the (a/a) genotype. The research resulted in a database of local and global significance, namely,

APA, Harvard, Vancouver, ISO, and other styles

43

Savicheva, Kateryna, Andrii Nesen, and Polina Semenovykh. "Polymorphism rs1799983 of the eNOS gene in patients with type 2 diabetes mellitus." Ukrainian Scientific Medical Youth Journal 144, no. 1 (2024): 55–60. http://dx.doi.org/10.32345/usmyj.1(144).2024.55-60.

Full text

Abstract:

Nowadays diabetes mellitus is one of the most common non-communicable human diseases after cardiovascular and oncological pathology, leading to disability and death. Establishing the association of the rs1799983 polymorphism of the eNOS gene with the development and progression of diabetes mellitus and further assessment of individual genetic risk is important for the development of a differentiated approach to the prevention and treatment of this pathology and its complications, depending on the hereditary predisposition of a particular patient. The purpose of the study was to determine the p

APA, Harvard, Vancouver, ISO, and other styles

44

H, Musa A., M. Y. Gwarzo, Mansurah A, et al. "Association of Endothelial Nitric Oxide Synthase (eNOS) Gene Polymorphism and Chronic Kidney Disease in Maiduguri, Borno State, Nigeria." EAS Journal of Biotechnology and Genetics 7, no. 02 (2025): 39–49. https://doi.org/10.36349/easjbg.2025.v07i02.004.

Full text

Abstract:

Chronic kidney disease (CKD) is becoming an important health problem worldwide. Since genetic risk factor is implicated in CKD development, this study aimed at assessing association of eNOS gene polymorphism and chronic kidney disease in Maiduguri. One hundred and forty (140) CKD patients and 70 apparently healthy controls participated in this study. Five milliliters (5ml) of whole blood were taken from each participant and sent to genetic laboratory. DNA was extracted from whole blood samples using GDSBio Blood Genomic DNA extraction kits. Then PCR and Agarose gel electrophoresis was performe

APA, Harvard, Vancouver, ISO, and other styles

45

Seckin, Yuksel, Ali Yigit, Elif Yesilada, et al. "Association of eNOS Gene Polymorphisms G894T and T-786C with Risk of Hepatorenal Syndrome." Gastroenterology Research and Practice 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/2579626.

Full text

Abstract:

Background. There are no studies investigating the relationship between endothelial nitric oxide synthase (eNOS) gene polymorphisms and hepatorenal syndrome (HRS).Aim.The purpose of this study is to elucidate whether eNOS gene polymorphisms (G894T and T-786C) play a role in the development of type-2 HRS.Methods. This study was carried out in a group of 92 patients with cirrhosis (44 patients with type-2 HRS and 48 without HRS) and 50 healthy controls. Polymorphisms were determined by polymerase chain reaction (PCR) and melting curve analysis.Results. We did not find any significant difference

APA, Harvard, Vancouver, ISO, and other styles

46

Demova, Hana, Jana Boleckova, Daniela Rose, et al. "Gene polymorphisms in patients with type 2 diabetes and diabetic nephropathy." Open Life Sciences 7, no. 2 (2012): 210–18. http://dx.doi.org/10.2478/s11535-012-0003-x.

Full text

Abstract:

AbstractA considerable variability in the incidence and prevalence of diabetic nephropathy (DN) coheres with an important contribution of multigenetic predisposition in the development of DN. Some genes, which probably participate in the pathogenesis of diabetic nephropathy, also play a role in the regulation of blood pressure, familial hyperlipidemia, familial hypertension and other diseases of the cardiovascular system. We have examined the association of diabetic nephropathy, nephropathy of non-diabetic origin, hypertension and of type 2 diabetes itself with several genetic polymorphisms (t

APA, Harvard, Vancouver, ISO, and other styles

47

Anisenkova, A., Y. Kovalev, A. Kuchinskii, et al. "Structural features of DNAin women with ischemic heart disease." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 14, no. 1 (2008): 53–58. http://dx.doi.org/10.18705/1607-419x-2008-14-1-53-58.

Full text

Abstract:

Clinical aspects, risk factors, results of selective coronary angiography, features of DNA-polymorphism (I/D polymorphism of gene ACE, isoalleles polymorphism gene APOE, SsTI polymorphism gene АРОСЗ, С677Т polymorphism of gene MTHFR, 4a/4b, G894T and T786C polymorphisms eNOs) in 89 women with a various degree of a coronary obstruction. In patients with sings of coronary artery atherosclerosis, familial history i heart disease was observed in most cases (greater degree on a line of mother). The obtained data show the reliable role of allele T, genotype CT gene MTHFRand gene-gene interaction of

APA, Harvard, Vancouver, ISO, and other styles

48

Cozma, Angela, Adela Sitar Taut, Olga Orasan, et al. "The Relationship Between eNOS (G894T ) Gene Polymorphism and Arterial Stiffness in Patients with Metabolic Syndrome." Revista de Chimie 69, no. 9 (2018): 2351–56. http://dx.doi.org/10.37358/rc.18.9.6532.

Full text

Abstract:

Metabolic syndrome (MS) is a clustering entity characterized by obesity, hypertension, hyperglycemia, dyslipidemia, and insulin resistance. Atherosclerotic lesions may be a complication of MS, arising from endothelial dysfunction and induced by decreased nitric oxide (NO) production. NO is synthesized by nitric oxide synthase (eNOS), encoded by the NOS3 gene, and displays anti-inflammatory, vasodilatory, and antiproliferative effects.We aimed to investigate the relationship between the G894T polymorphism of the eNOS gene and metabolic syndrome (including its components) and the association of

APA, Harvard, Vancouver, ISO, and other styles

49

GIANNOPOULOS, SOTIRIOS, SOFIA MARKOULA, IOANNIS ASPROUDIS, et al. "Endothelial nitric oxide synthase polymorphism (G894T) and nonarteritic anterior ischemic optic neuropathy." Visual Neuroscience 27, no. 5-6 (2010): 183–85. http://dx.doi.org/10.1017/s0952523810000350.

Full text

Abstract:

AbstractNonarteritic anterior ischemic optic neuropathy (NAION) is associated with vascular risk factors and a genetic predisposition for NAION. In this study, we examined the potential association of endothelial nitric oxide synthase (eNOS) G894T polymorphism with NAION. For this, 45 patients (29 men and 16 women) and 193 controls (122 men and 71 women) were enrolled prospectively and genotyped for eNOS genes. Genotypes were determined by polymerase chain reaction and restriction enzyme analysis. The prevalence of eNOS polymorphisms was estimated in NAION patients and controls. Genotype frequ

APA, Harvard, Vancouver, ISO, and other styles

50

Petyunina, Olga V., Mykola P. Kopytsya, Denis P. Babichev, and Alexander E. Berezin. "Short-term clinical outcomes in patients with acute myocardial infarction after successful percutaneous coronary revascularization: the role of promoter polymorphism of the endothelial nitric oxide synthase gene." Biomedical Research and Therapy 6, no. 5 (2019): 3166–79. http://dx.doi.org/10.15419/bmrat.v6i5.543.

Full text

Abstract:

Background: The purpose of this study was to investigate the associations between variants of a promoter polymorphism of the endothelial nitric oxide synthase (eNOS) gene and clinical outcomes in acute ST-segment elevation myocardial infarction (STEMI) patients after a successful primary percutaneous coronary artery intervention (PCI). Methods: 177 patients with acute STEMI, 82 patients with angiographically proven stable coronary artery disease, and healthy volunteers were included in the study. The primary end-point was a combined event (follow-up major adverse cardiac events –MACEs an

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!